aminopyrine has been researched along with morphinans in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, GM; Mannering, GJ | 1 |
| Correia, MA; Mannering, GJ | 1 |
| Fujita, T; Mannering, GJ | 1 |
| Hildebrandt, AG; Roots, I; Speck, M | 1 |
| Patel, JM; Pawar, SS | 2 |
| Kamataki, T; Kitagawa, H | 1 |
| Bickel, MH; Gigon, PL | 1 |
| Hildebrandt, AG; Roots, I | 1 |
| Wilson, JT | 3 |
| Coon, MJ; Lu, AY; Strobel, HW | 2 |
| Fürst, S; Knoll, J; Mészáros, Z | 1 |
| Gigon, PL; Gillette, JR; Gram, TE | 1 |
| Gillette, JR; Sasame, HA | 1 |
| Cohen, BS; Estabrook, RW | 1 |
| Belfi, KJ; Masters, BS; Nelson, EB; Raj, PP | 1 |
| Gillette, JR; Hamrick, M; Sasame, H; Stripp, B; Zampaglione, N | 1 |
| Orrenius, S | 1 |
| Donahue, JD; Johnson, RK; Jondorf, WR; Mazel, P | 1 |
| Cinti, DL; Moldeus, P; Schenkman, JB | 1 |
| Allen, LM; Creaven, PJ | 1 |
| Stesin, AJ; Takemori, AE; Tulunay, FC | 1 |
| Neal, RA; Roth, JA | 1 |
| Schenkman, JB | 1 |
| Hildebrandt, AG | 1 |
| Davis, DC; Gillette, JR; Gram, TE; Guarino, AM; Reagan, RL; Schroeder, DH | 1 |
| Kupfer, D; Orrenius, S | 1 |
| Culp, HW; Gibson, WR; Marshall, FJ; McMahon, RE; Miller, WM; Mills, J | 1 |
31 other study(ies) available for aminopyrine and morphinans
| Article | Year |
|---|---|
Involvement of a hydrophobic site in the inhibition of the microsomal p-hydroxylation of aniline by alcohols.
Topics: 1-Propanol; Alcohols; Aminopyrine; Aniline Compounds; Animals; Binding Sites; Binding, Competitive; Butanols; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dealkylation; Electron Transport Complex IV; Ethanol; Hexanols; Hydroxylation; In Vitro Techniques; Kinetics; Male; Methadone; Microsomes, Liver; Morphinans; NADP; Naphthalenes; Octanols; Rats; Sulfonic Acids | 1973 |
Reduced diphosphopyridine nucleotide synergism of the reduced triphosphopyridine nucleotide-dependent mixed-function oxidase system of hepatic microsomes. II. Role of the type I drug-binding site of cytochrome P-450.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Codeine; Cyanides; Cytochrome P-450 Enzyme System; Drug Synergism; Female; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Morphinans; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Phospholipases; Proadifen; Protein Binding; Rats | 1973 |
Electron transport components of hepatic microsomes. Solubilization, resolution, and recombination to reconstitute aniline hydroxylase activity.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Chloromercuribenzoates; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Phenobarbital; Rats; Solubility; Structure-Activity Relationship; Vitamin K | 1973 |
The effects of substrates of mixed function oxidase on ethanol oxidation in rat liver microsomes.
Topics: Acetaldehyde; Aminopyrine; Animals; Azides; Catalase; Cytochrome P-450 Enzyme System; Ethanol; Formaldehyde; Heme; Hydrogen Peroxide; Kinetics; Male; Mathematics; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Oxygen Consumption; Rats | 1974 |
Riboflavin and drug metabolism in adult male and female rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Body Weight; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Diet; Electron Transport; Female; In Vitro Techniques; Liver; Male; Microsomes, Liver; Morphinans; NADP; Organ Size; Phenobarbital; Proteins; Rats; Riboflavin Deficiency; Sex Factors; Time Factors | 1974 |
Effects of lipid peroxidation on activities of drug-metabolizing enzymes in liver microsomes of rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Cobalt; Codeine; Edetic Acid; In Vitro Techniques; Iron; Kinetics; Lipid Metabolism; Lipids; Male; Manganese; Microsomes, Liver; Morphinans; Peroxides; Phenanthrolines; Proadifen; Rats | 1973 |
Drug metabolism by hepatic microsomes from phenobarbital-treated or starved male and female rats in the presence of inhibitors.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Liver; Male; Methylation; Microsomes, Liver; Morphinans; Niacinamide; Organ Size; Phenobarbital; Proadifen; Rats; Starvation | 1971 |
Active centers of microsomal cytochrome P-450 determined with metyrapone by mutural depletion system kinetics.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Catalysis; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Morphinans; Morphine; Oxidoreductases, N-Demethylating; Phenobarbital; Protein Binding; Rats | 1973 |
Decreased hepatic microsomal drug metabolism after the injection of a mixture containing somatotropin, corticotropin and prolactin.
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Cattle; Depression, Chemical; Formaldehyde; Growth Hormone; Hexobarbital; Hot Temperature; Liver; Male; Morphinans; Prolactin; Rats; Sheep; Time Factors | 1968 |
Identification of somatotropin as the hormone in a mixture of somatotropin, adrenocorticotropic hormone and prolactin which decreased liver drug metabolism in the rat.
Topics: Adrenocorticotropic Hormone; Albumins; Aminopyrine; Animals; Formaldehyde; Growth Hormone; Hexobarbital; Liver; Male; Microsomes; Morphinans; Prolactin; Rats | 1969 |
Further observations on hepatic drug metabolism in rats treated with a mixture of somatotropin, corticotropin and prolactin.
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Growth Hormone; Hexobarbital; Liver; Male; Microsomes, Liver; Morphinans; Neoplasm Transplantation; Phenobarbital; Pituitary Neoplasms; Prolactin; Rats | 1969 |
Properties of a solubilized form of the cytochrome P-450-containing mixed-function oxidase of liver microsomes.
Topics: Alkanes; Aminopyrine; Animals; Benzphetamine; Cyclohexanes; Cytochromes; Electron Transport Complex IV; Fatty Acids; Hexobarbital; Lipid Metabolism; Microsomes, Liver; Morphinans; Phosphatidylcholines; Rabbits; Rats; Solubility; Triolein | 1970 |
The pharmacology of 1,6-dimethyl-3-carbethoxy-4-oxo-6,7,8,9-tetrahydrohomopyrimidazol-methylsulphate (MZ-144), a new, potent, non-narcotic analgesic. II. Toxicity and analgetic effect of MZ-144 compared to narcotic and non-narcotic analgesics.
Topics: Aminopyrine; Amobarbital; Analgesics; Animals; Aspirin; Blood; Cats; Codeine; Diazepam; Dogs; Drug Antagonism; Drug Synergism; Glutethimide; Guinea Pigs; Haplorhini; Methods; Mice; Morphinans; Morphine; Naphthalenes; Pain; Phenacetin; Pyrimidinones; Rabbits; Rats; Synaptic Transmission | 1971 |
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates | 1969 |
Studies on the relationship between the effects of various substances on absorption spectrum of cytochrome P-450 and the reduction of p-nitrobenzoate by mouse liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Monoxide; Cytochromes; Ethylamines; Hexobarbital; Imidazoles; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Spectrophotometry | 1969 |
Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation.
Topics: Aminopyrine; Animals; Appetite Depressants; Benzphetamine; Cytochromes; Depression, Chemical; Ethers; Fatty Acids; Formaldehyde; Hexobarbital; Lipid Metabolism; Liver; Microsomes; Mixed Function Oxygenases; Morphinans; NADP; Oxidoreductases; Phenethylamines; Phenobarbital; Propylamines; Rabbits; Spectrophotometry | 1969 |
Microsomal electron transport reactions. II. The use of reduced triphosphopyridine nucleotide and-or reduced diphosphopyridine nucleotide for the oxidative N-demethylation of aminopyrine and other drug substrates.
Topics: Aminopyrine; Animals; Codeine; Dealkylation; Electron Transport; Fasting; Formaldehyde; Kinetics; Male; Methylation; Microsomes; Microsomes, Liver; Morphinans; NAD; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Rabbits | 1971 |
Oxidative drug metabolism in human liver microsomes.
Topics: Adolescent; Adult; Aminopyrine; Aniline Compounds; Benzphetamine; Biotransformation; Chlorpromazine; Codeine; Cytochromes; Dealkylation; Dextropropoxyphene; Female; Humans; Immunodiffusion; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Morphinans; NADP; Oxidoreductases; Spectrophotometry | 1971 |
Studies of the stoichiometric relationships between the oxidation of drugs and the oxidation of reduced pyridine nucleotides by liver microsomal enzymes.
Topics: Adenine Nucleotides; Aminopyrine; Cytochromes; Hexobarbital; Imipramine; Microsomes, Liver; Morphinans; NADP; Nucleotides; Oxidation-Reduction; Pharmaceutical Preparations; Pyridines | 1971 |
Molecular aspects of drug metabolism.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Drug Interactions; Electron Transport; Fats; Hexobarbital; Hydroxylation; Lipids; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Pharmaceutical Preparations; Rats; Solubility; Spectrophotometry; Steroids; Testosterone; Triamcinolone | 1971 |
Factors involved in the inhibition of drug metabolism by (-)-emetine.
Topics: Aminopyrine; Aniline Compounds; Animals; Azo Compounds; Carbon Monoxide; Cytochromes; Dealkylation; Emetine; Female; In Vitro Techniques; Kinetics; Mercaptopurine; Metabolism; Microsomes, Liver; Morphinans; NADP; Nitrogen; Nucleosides; Oxidoreductases; Rats; Ribonucleosides; Tetrazolium Salts | 1971 |
Kinetic parameters of drug-metabolizing enzymes in Ca 2+ -sedimented microsomes from rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Calcium; Cell Fractionation; Centrifugation, Density Gradient; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Dealkylation; Hexobarbital; Kinetics; Male; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Rats; Spectrophotometry; Sucrose; Ultracentrifugation | 1972 |
In vitro activation of isophosphamide (NSC-109724), a new oxazaphosphorine, by rat liver microsomes.
Topics: Alkylating Agents; Alkylation; Aminopyrine; Aniline Compounds; Animals; Cyclic P-Oxides; Cyclophosphamide; Dealkylation; DNA; Enzyme Activation; Ethylamines; Kinetics; Liver; Male; Microsomes, Liver; Morphinans; NADP; Oxazines; Oxidoreductases; Phenobarbital; Phosphoranes; Proadifen; Proteins; Rats; RNA | 1972 |
A single-dose suppression test in morphine-dependent mice.
Topics: Aminopyrine; Analgesics; Animals; Behavior, Animal; Humans; Isonipecotic Acids; Levorphanol; Male; Methadone; Mice; Morphinans; Morphine; Morphine Dependence; Motor Activity; Nalorphine; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome | 1974 |
Effect of sex and age on hepatic N-demethylation and hydroxylation reactions in phenobarbital induced rats.
Topics: Acetanilides; Age Factors; Aminopyrine; Aniline Compounds; Animals; Enzyme Induction; Female; Liver; Male; Methyltransferases; Mixed Function Oxygenases; Morphinans; Morphine; Phenobarbital; Rats; Sex Factors | 1973 |
Spectral studies of the binding of O,O-diethyl p-nitrophenylphosphorothionate (parathion) to cytochrome P-450.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Binding Sites; Cytochromes; Hexobarbital; Male; Microsomes, Liver; Morphinans; Parathion; Phenobarbital; Protein Binding; Rabbits; Spectrophotometry | 1972 |
Rate-limiting steps in drug metabolism.
Topics: Aminopyrine; Aniline Compounds; Chemical Phenomena; Chemistry, Physical; Cytochromes; Microsomes, Liver; Morphinans; Oxidoreductases; Pharmaceutical Preparations | 1971 |
The binding of metyrapone to cytochrome P-450 and its inhibitory action on liver microsomal mixed-function oxidase reactions.
Topics: Acetanilides; Aminopyrine; Animals; Binding Sites; Codeine; Cytochromes; Hexobarbital; Metyrapone; Microsomes, Liver; Morphinans; Nitrophenols; Oxidation-Reduction; Rats; Spectrum Analysis | 1971 |
The effect of starvation on the kinetics of drug oxidation by hepatic microsomal enzymes from male and female rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Kinetics; Liver; Male; Microscopy, Electron; Microsomes, Liver; Morphinans; Oxidation-Reduction; Proteins; Rats; Sex Factors; Sleep; Starvation | 1970 |
Interaction of drugs, steroids and fatty acids with liver-microsomal cytochrome P-450.
Topics: Aminopyrine; Animals; Chemical Phenomena; Chemistry; Cytochromes; Fatty Acids; Hexobarbital; Male; Microsomes, Liver; Morphinans; Oxidation-Reduction; Oxygenases; Protein Binding; Rats; Spectrophotometry; Steroids; Testosterone; Triamcinolone Acetonide | 1970 |
Demethylation studies. VI. The inhibition of hepatic microsomal oxygenation by 2,4-dichloro(6-phenylphenoxy)ethylamine and related compounds.
Topics: Aminopyrine; Amitriptyline; Animals; Butylamines; Carbamates; Carbon Isotopes; Dextropropoxyphene; Dogs; Ethylamines; Hexobarbital; Imipramine; In Vitro Techniques; Liver; Male; Mice; Microsomes; Morphinans; Naphthalenes; Nitriles; Phenethylamines; Phenobarbital; Propylamines; Rats | 1969 |