Page last updated: 2024-08-17

aminopyrine and mercaptopurine

aminopyrine has been researched along with mercaptopurine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Donahue, JD; Johnson, RK; Jondorf, WR; Mazel, P1
Beck, FJ; Whitehouse, MW1
Bresnick, E; Grogan, DE; Lane, M; Smith, FE; Stone, K1
Dietrich, FM; Komarek, A1
Kadokawa, T; Nakamura, H; Nakamura, K; Nakatsuji, K1
BRESNICK, E; YANG, HY1

Other Studies

8 other study(ies) available for aminopyrine and mercaptopurine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Factors involved in the inhibition of drug metabolism by (-)-emetine.
    Biochemical pharmacology, 1971, Volume: 20, Issue:5

    Topics: Aminopyrine; Aniline Compounds; Animals; Azo Compounds; Carbon Monoxide; Cytochromes; Dealkylation; Emetine; Female; In Vitro Techniques; Kinetics; Mercaptopurine; Metabolism; Microsomes, Liver; Morphinans; NADP; Nitrogen; Nucleosides; Oxidoreductases; Rats; Ribonucleosides; Tetrazolium Salts

1971
Impaired drug metabolism in rats associated with acute inflammation: a possible assay for anti-injury agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:1

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Biological Assay; Cyclophosphamide; Dexamethasone; Disease Models, Animal; Drug Evaluation, Preclinical; Freund's Adjuvant; Hexobarbital; Humans; Hydroxylation; Inflammation; Irritants; Male; Mercaptopurine; Microsomes, Liver; Rats; Rats, Inbred Lew; Sleep; Time Factors

1974
Interaction of flavins and chloramphenicol with microsomal enzyme systems.
    Biochemical pharmacology, 1972, Dec-01, Volume: 21, Issue:23

    Topics: Acetanilides; Aminopyrine; Animals; Anisoles; Chloramphenicol; Dealkylation; Drug Interactions; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Formaldehyde; Hexobarbital; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mercaptopurine; Mice; Microsomes, Liver; Nitro Compounds; Organ Size; Proteins; Sleep; Time Factors

1972
Chemical prevention of experimental allergic encephalomyelitis in rats: a quantitative evaluation of steroids and various non-steroid drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:2

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Bis-Trimethylammonium Compounds; Cortisone; Cyclophosphamide; Dexamethasone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Flumethasone; Freund's Adjuvant; Glucocorticoids; Guanethidine; Guinea Pigs; Hydrocortisone; Lethal Dose 50; Male; Mercaptopurine; Paramethasone; Phenylbutazone; Prednisolone; Prednisone; Rats; Sodium Salicylate; Spinal Cord

1971
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capillary Permeability; Carrageenan; Croton Oil; Depression, Chemical; Edema; Exudates and Transudates; Female; Guinea Pigs; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Mice; Phenylbutazone; Phenytoin; Pregnanes; Protein Denaturation; Rabbits; Radiation-Protective Agents; Rats; Sulfones; Yeast, Dried

1970
THE INFLUENCE OF PHENOBARBITAL ADMINISTRATION UPON THE "SOLUBLE" NADP-REQUIRING ENZYMES IN LIVER.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Aminopyrine; Benzopyrenes; Citrates; Diphenhydramine; Ethionine; Fluorouracil; Gluconates; Hexosephosphates; Isocitrate Dehydrogenase; Liver; Mercaptopurine; Methylcholanthrene; NADP; Oxidoreductases; Pharmacology; Phenobarbital; Phenylalanine; Rats; Research; Uracil

1964