aminopyrine has been researched along with formaldehyde in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (87.76) | 18.7374 |
| 1990's | 3 (6.12) | 18.2507 |
| 2000's | 2 (4.08) | 29.6817 |
| 2010's | 1 (2.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Cinti, DL; Denk, H; Keyes, SR; Moldeus, PW; Schenkman, JB; Schulz, RA | 1 |
| Harada, T; Inoki, R; Kaya, H; Takahashi, H | 1 |
| Matsubara, T; Tochino, Y; Touchi, A | 1 |
| Matsubara, T; Touchi, A | 1 |
| Grant, L; Powis, G | 1 |
| Jensen, DE; Stelman, GJ; Williams, AW | 1 |
| Cederbaum, AI; Dicker, E | 2 |
| Bhatt, HS; Combes, B; Lober, SB | 1 |
| Black, KA; Coffman, BL; Dannan, GA; Green, MD; Guengerich, FP; Tephly, TR | 1 |
| Antoni, F; Bánhegyi, G; Garzó, T; Mandl, J | 1 |
| Klinger, W | 2 |
| Hildebrandt, AG; Roots, I; Speck, M | 1 |
| Gillette, JR; Kato, R | 1 |
| Wilson, JT | 2 |
| Heni, N; Remmer, H | 1 |
| Anspach, K; Mörsdorf, K | 1 |
| Dallner, G; Ernster, L; Orrenius, S | 1 |
| Fouts, JR; Gram, TE; Wilson, JT | 1 |
| Coon, MJ; Lu, AY; Strobel, HW | 1 |
| Cohen, BS; Estabrook, RW | 3 |
| Hálek, J; Jezdinský, J | 1 |
| Carpenter, MP | 1 |
| Bresnick, E; Grogan, DE; Lane, M; Smith, FE; Stone, K | 1 |
| Furkert, K | 1 |
| Magistretti, MJ; Massarani, E; Nardi, D | 2 |
| Kamataki, T; Kitagawa, H | 1 |
| Usui, Y | 1 |
| Himuro, I; Sato, N; Shioya, A | 1 |
| Imamura, H; Maruyama, Y; Nakanishi, M | 1 |
| Pardo, EG; Rodgiguez, R | 1 |
| Ernst, L; Meier, W; Mühle, H; Renker, H | 1 |
| Fuller, GC; Lal, H; Olshan, AM | 1 |
| Soyka, LF | 1 |
| Creighton, JM; Marks, GS | 1 |
| Naruse, S; Ohkubo, T; Shibata, M; Takahashi, H | 1 |
| Gescher, A; Raymont, C | 1 |
| Kulkarni, AP; Yang, X | 1 |
| Chen, JH; Ding, H; Kong, R; Li, QX; Peng, RX; Wang, H; Yu, JP; Zhang, YH | 1 |
| Doenhoff, MJ; Mostafa, MH; O'Connor, PJ; Rafferty, JA; Saeed, HM | 1 |
| Cechinel-Filho, V; Corrêa, R; de Campos, F; de Souza, MM; Nunes, RJ; Yunes, RA | 1 |
| AWE, W; BUERHOP, R; STOY-GEILICH, E | 1 |
| CHEMNITIUS, KH; KLEE, H; REIHL, G | 1 |
1 review(s) available for aminopyrine and formaldehyde
| Article | Year |
|---|---|
[Otologic agents. 13].
Topics: Adrenal Cortex Hormones; Aminopyrine; Anesthetics, Local; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Antipyrine; Benzocaine; Chloramphenicol; Disinfectants; Ear Diseases; Formaldehyde; Humans; Hydrocortisone; Lidocaine; Neomycin; Nitrofurazone; Prednisolone; Procaine; Tetracaine; Toluene | 1967 |
48 other study(ies) available for aminopyrine and formaldehyde
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Hepatic organelle interaction. IV. Mechanism of succinate enhancement of formaldehyde accumulation from endoplasmic reticulum N-dealkylations.
Topics: Aldehyde Oxidoreductases; Aminopyrine; Animals; Antimycin A; Cyanides; Endoplasmic Reticulum; Formaldehyde; Liver; Male; Microsomes, Liver; Mitochondria, Liver; NAD; Oligomycins; Rats; Rotenone; Semicarbazides; Succinates | 1976 |
A test for analgesics as an indicator of locomotor activity in writhing mice.
Topics: Acetates; Aminopyrine; Analgesics; Animals; Drug Interactions; Formaldehyde; Male; Mice; Morphine; Motor Activity; Narcotics; Pain; Time Factors | 1979 |
Hepatic aminopyrine N-demethylase system: further studies of assay procedure.
Topics: Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Formaldehyde; Liver; Male; Methods; Microsomes, Liver; Morphine; Oxidoreductases, N-Demethylating; Rats; Semicarbazides; Time Factors | 1977 |
Hepatic aminopyrine N-demethylase system: effect of cyanide on microsomal N-demethylase activity.
Topics: Aminopyrine; Animals; Cyanides; Cytochrome P-450 Enzyme System; Depression, Chemical; Formaldehyde; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats | 1977 |
The effect of inhibitors of alcohol metabolism upon the changes in the hepatic microsomal metabolism of foreign compounds produced by the acute administration of some alcohols to the rat.
Topics: Alcohol Oxidoreductases; Alcohols; Aminopyrine; Aniline Compounds; Animals; Anti-Bacterial Agents; Disulfiram; Formaldehyde; Male; Microsomes, Liver; Oximes; Pyrazoles; Rats; Time Factors | 1976 |
Microsomally-mediated denitrosation of nitrosoguanidinium compounds.
Topics: Aminopyrine; Animals; Cimetidine; Cricetinae; Formaldehyde; Guanidines; Methylnitronitrosoguanidine; Microsomes, Liver; NADP; Nitrates; Nitrites; Nitrosation; Nitrosoguanidines; Rats | 1990 |
Inhibition of CO2 production from aminopyrine or methanol by cyanamide or crotonaldehyde and the role of mitochondrial aldehyde dehydrogenase in formaldehyde oxidation.
Topics: Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Aldehydes; Aminopyrine; Animals; Carbon Dioxide; Cyanamide; Cyanides; Formaldehyde; Glyoxylates; Hydrogen Peroxide; Male; Methanol; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1986 |
Effect of glutathione depletion on aminopyrine and formaldehyde metabolism.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Breath Tests; Buthionine Sulfoximine; Formaldehyde; Formates; Glutathione; Ketones; Male; Maleates; Methionine Sulfoximine; Microsomes, Liver; Rats; Rats, Inbred Strains | 1988 |
Effect of suicide substrate on the metabolism of steroids and xenobiotics and on cytochrome P-450 apoproteins.
Topics: Aminopyrine; Animals; Apoproteins; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Formaldehyde; Formates; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains; Testosterone | 1986 |
Interrelationship between aminopyrine oxidation and gluconeogenesis in hepatocytes prepared from fructose-pretreated mice.
Topics: Aminopyrine; Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Formaldehyde; Fructose; Gluconeogenesis; Hexobarbital; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Oxidation-Reduction; Phenobarbital | 1987 |
Amidopyrine-N-demethylation by lung 9000 x g supernatant of newborn and adult rats.
Topics: Aminopyrine; Animals; Animals, Newborn; Biotransformation; Formaldehyde; Glucosephosphate Dehydrogenase; Hydroxylation; Liver; Lung; Methylation; NADP; Rats | 1973 |
The effects of substrates of mixed function oxidase on ethanol oxidation in rat liver microsomes.
Topics: Acetaldehyde; Aminopyrine; Animals; Azides; Catalase; Cytochrome P-450 Enzyme System; Ethanol; Formaldehyde; Heme; Hydrogen Peroxide; Kinetics; Male; Mathematics; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Oxygen Consumption; Rats | 1974 |
Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminopyrine; Aniline Compounds; Animals; Castration; Diabetes Mellitus, Experimental; Epinephrine; Female; Formaldehyde; Hexobarbital; Hypoxia; In Vitro Techniques; Liver; Male; Microsomes; Mixed Function Oxygenases; Morphine; Rats; Sex; Thyroxine; Zoxazolamine | 1965 |
Decreased hepatic microsomal drug metabolism after the injection of a mixture containing somatotropin, corticotropin and prolactin.
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Cattle; Depression, Chemical; Formaldehyde; Growth Hormone; Hexobarbital; Hot Temperature; Liver; Male; Morphinans; Prolactin; Rats; Sheep; Time Factors | 1968 |
Identification of somatotropin as the hormone in a mixture of somatotropin, adrenocorticotropic hormone and prolactin which decreased liver drug metabolism in the rat.
Topics: Adrenocorticotropic Hormone; Albumins; Aminopyrine; Animals; Formaldehyde; Growth Hormone; Hexobarbital; Liver; Male; Microsomes; Morphinans; Prolactin; Rats | 1969 |
[Effect of carbon tetrachloride on endoplasmic enzymes in rat liver].
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cholinesterases; Cytochromes; Endoplasmic Reticulum; Formaldehyde; Glucose-6-Phosphatase; Hexobarbital; Male; Membranes; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Protein Binding; Rabbits; Rats; Spectrophotometry | 1971 |
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Dextrans; Dimethyl Sulfoxide; Disease Models, Animal; Edema; Flufenamic Acid; Formaldehyde; Granuloma; Indomethacin; Inflammation; Kaolin; Male; Mefenamic Acid; Ovalbumin; Oxyphenbutazone; Phenylbutazone; Prednisolone; Rats; Sodium Salicylate; Trypsin | 1971 |
Inhibition of the TPNH-linked lipid peroxidation of liver microsomes by drugs undergoing oxidative demethylation.
Topics: Adenine Nucleotides; Aldehydes; Aminopyrine; Animals; Ascorbic Acid; Codeine; Formaldehyde; In Vitro Techniques; Iron; Lipid Metabolism; Liver; Microsomes; NADP; Peroxides; Rats | 1964 |
Some characteristics of hepatic microsomal systems which metabolize aminopyrine in the rat and rabbit.
Topics: Aminopyrine; Animals; Antipyrine; Chromatography, Thin Layer; Formaldehyde; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Microsomes; NADP; Oxygen; Phenobarbital; Rabbits; Rats | 1968 |
Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation.
Topics: Aminopyrine; Animals; Appetite Depressants; Benzphetamine; Cytochromes; Depression, Chemical; Ethers; Fatty Acids; Formaldehyde; Hexobarbital; Lipid Metabolism; Liver; Microsomes; Mixed Function Oxygenases; Morphinans; NADP; Oxidoreductases; Phenethylamines; Phenobarbital; Propylamines; Rabbits; Spectrophotometry | 1969 |
Microsomal electron transport reactions. I. Interaction of reduced triphosphopyridine nucleotide during the oxidative demethylation of aminopyrine and cytochrome b 5 reduction.
Topics: Aminopyrine; Animals; Cytochromes; Dealkylation; Electron Transport; Fasting; Fluorometry; Formaldehyde; Isocitrate Dehydrogenase; Kinetics; Male; Methylation; Microsomes, Liver; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Rabbits; Spectrophotometry; Ultraviolet Rays | 1971 |
Microsomal electron transport reactions. II. The use of reduced triphosphopyridine nucleotide and-or reduced diphosphopyridine nucleotide for the oxidative N-demethylation of aminopyrine and other drug substrates.
Topics: Aminopyrine; Animals; Codeine; Dealkylation; Electron Transport; Fasting; Formaldehyde; Kinetics; Male; Methylation; Microsomes; Microsomes, Liver; Morphinans; NAD; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Rabbits | 1971 |
Microsomal electron transport reactions. 3. Cooperative interactions between reduced diphosphopyridine nucleotide and reduced triphosphopyridine nucleotide linked reactions.
Topics: Aminopyrine; Animals; Cytochromes; Electron Transport; Fasting; Fluorometry; Formaldehyde; Isocitrate Dehydrogenase; Male; Microsomes, Liver; Models, Biological; NAD; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Rabbits; Spectrophotometry | 1971 |
The effects of some analgesics and neuroleptics upon the reflexive and affective components of the formaldehyde- and bradykinin-induced nociceptive reactions in rats.
Topics: Aminopyrine; Analgesics; Animals; Behavior, Animal; Bradykinin; Chlorpromazine; Dose-Response Relationship, Drug; Emotions; Formaldehyde; Methotrimeprazine; Morphine; Pain; Rats; Rats, Inbred Strains; Reflex | 1974 |
Vitamin E and microsomal drug hydroxylations.
Topics: Aminopyrine; Aniline Compounds; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Cobalt; Codeine; Cytochromes; Dactinomycin; Drug Synergism; Edetic Acid; Female; Formaldehyde; Hydroxylation; Kinetics; Male; Manganese; Microsomes, Liver; Rats; Sex Factors; Subcellular Fractions; Vitamin E | 1972 |
Interaction of flavins and chloramphenicol with microsomal enzyme systems.
Topics: Acetanilides; Aminopyrine; Animals; Anisoles; Chloramphenicol; Dealkylation; Drug Interactions; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Formaldehyde; Hexobarbital; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mercaptopurine; Mice; Microsomes, Liver; Nitro Compounds; Organ Size; Proteins; Sleep; Time Factors | 1972 |
Activity course of amidopyrine-N-demethylation by 9000 x g-liver supernatant of weanling and adult rats of both sexes after administration of carbon tetrachloride.
Topics: Age Factors; Aminopyrine; Animals; Carbon Tetrachloride Poisoning; Centrifugation, Density Gradient; Female; Formaldehyde; Kinetics; Male; Microsomes, Liver; Monoamine Oxidase; Rats; Sex Factors; Time Factors | 1973 |
4-phenylglioxylidenamino-antipyrine with antiphlogistic and analgesic activity.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Antiviral Agents; Chick Embryo; Depression, Chemical; Edema; Formaldehyde; Mice; Mycobacterium tuberculosis; Phenylbutazone; Rats; Vaccinia virus | 1969 |
Studies on drug metabolism. XII. Activity of liver microsomal drug-metabolizing enzymes in human liver.
Topics: Adult; Aged; Aminopyrine; Aniline Compounds; Animals; Antipyrine; Female; Formaldehyde; Haplorhini; Humans; Male; Microsomes, Liver; Middle Aged; Phenols; Postmortem Changes; Rats | 1971 |
[Pharmacological action of anti-inflammatory drugs in inflammation in the early stage].
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Depression, Chemical; Dextrans; Edema; Formaldehyde; Inflammation; Peptide Hydrolases; Rats; Time Factors | 1971 |
A photoelectric method for estimating inflammatory intensity in mice and its application to the anti-inflammatory evaluation of glucuronic acid derivatives.
Topics: Acetates; Aminopyrine; Animals; Calcium Chloride; Coloring Agents; Dermatitis; Dextrans; Drug Synergism; Formaldehyde; Glucuronates; Histamine; Hydrocortisone; Inflammation; Male; Methods; Mice; Passive Cutaneous Anaphylaxis; Salicylates; Serum Albumin, Bovine; Spectrophotometry; Tripelennamine | 1967 |
4(beta-benzoylvinyl)-antipyrine derivatives after antiphlogistic and analgesic activity.
Topics: Acetophenones; Aminopyrine; Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Anticonvulsants; Antipyrine; Antitussive Agents; Coronary Vessels; Edema; Formaldehyde; Mice; Muscle Relaxants, Central; Muscle, Smooth; Phenylbutazone; Propiophenones; Pyrazoles; Rabbits; Rats; Vasodilator Agents | 1969 |
Pharmacological investigations of 2-amino-3-ethoxy-carbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Bradykinin; Carrageenan; Depression, Chemical; Dextrans; Edema; Exudates and Transudates; Formaldehyde; Granuloma; Guinea Pigs; Hydrocortisone; Male; Mefenamic Acid; Mice; Oxyphenbutazone; Peritonitis; Permeability; Phenylbutazone; Polysaccharides, Bacterial; Pyridines; Rabbits; Radiation-Protective Agents; Rats; Serotonin Antagonists; Wound Healing | 1970 |
Drug reversal of pain induced functional impairment.
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Biological Assay; Codeine; Dextropropoxyphene; Dogs; Electrophysiology; Female; Formaldehyde; Hindlimb; Injections, Intra-Articular; Male; Movement Disorders; Pain; Statistics as Topic; Transducers | 1968 |
[Basically substituted 4-acylaminophenazones: synthesis and pharmacological effect].
Topics: Albumins; Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Chemistry, Pharmaceutical; Edema; Formaldehyde; Methods; Mice; Potentiometry; Pyrazoles; Rats; Serotonin Antagonists | 1968 |
The stimulatory effect of phenobarbital on the N-demethylation of P-chloro-N-methylaniline.
Topics: Aminopyrine; Aniline Compounds; Animals; Enzyme Induction; Female; Formaldehyde; Liver; Male; Methods; Methylation; Microsomes; Phenobarbital; Rats | 1969 |
Determinants of hepatic aminopyrine demethylase activity.
Topics: Age Factors; Aminopyrine; Animals; Animals, Newborn; Body Weight; Deficiency Diseases; Female; Formaldehyde; Hexosephosphates; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Male; Microsomes; Nutritional Physiological Phenomena; Organ Size; Oxidoreductases; Rats; Sex Factors; Testosterone; Time Factors | 1969 |
Drug-induced porphytin biosynthesis. I. The effect of porphyria-inducing drugs on N-demethylase activity of chick embryo liver.
Topics: Amides; Aminopyrine; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Formaldehyde; In Vitro Techniques; Liver; Microsomes; Oxidoreductases; Phenobarbital; Porphyrias; Porphyrins; Pyridines | 1969 |
Effect of ethanol and metabolic substrates on the oxidation of aminopyrine, formaldehyde and formate by isolated hepatocytes.
Topics: Aminopyrine; Animals; Carbon Dioxide; Cells, Cultured; Ethanol; Formaldehyde; Formates; Fructose; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol; Xylitol | 1983 |
[Formalin-induced minor tremor response as an indicator of pain].
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Formaldehyde; Guinea Pigs; Hydrocortisone; Indomethacin; Levallorphan; Male; Morphine; Pain; Pyridinolcarbamate; Tremor | 1984 |
Studies of the metabolism of N-methyl containing anti-tumour agents: 14CO2 breath analysis after administration of 14C-labelled N-methyl drugs, formaldehyde and formate in mice.
Topics: Altretamine; Aminopyrine; Animals; Antineoplastic Agents; Biotransformation; Caffeine; Carbon Dioxide; Formaldehyde; Formates; Male; Mice; Mice, Inbred CBA; Procarbazine | 1981 |
N-dealkylation of aminopyrine catalyzed by soybean lipoxygenase in the presence of hydrogen peroxide.
Topics: Aminopyrine; Dealkylation; Formaldehyde; Free Radicals; Glycine max; Hydrogen Peroxide; Lipoxygenase; Substrate Specificity | 1998 |
Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro.
Topics: Adrenal Glands; Aminopyrine; Benzphetamine; Cytochrome P-450 Enzyme System; Erythromycin; Fetus; Formaldehyde; Humans; Microsomes, Liver; Mitochondria; Troleandomycin | 1999 |
Evidence for the presence of active cytochrome P450 systems in Schistosoma mansoni and Schistosoma haematobium adult worms.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Cricetinae; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Activation; Ethylmorphine; Female; Formaldehyde; Immunoblotting; Male; Mice; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxazines; Rats; Schistosoma haematobium; Schistosoma mansoni; Substrate Specificity | 2002 |
Studies on new cyclic imides obtained from aminophenazone with analgesic properties. Potent effects of a 3,4-dichloromaleimide derivative.
Topics: Acetic Acid; Aminopyrine; Analgesics, Non-Narcotic; Animals; Capsaicin; Formaldehyde; Imides; Indicators and Reagents; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peritonitis; Reaction Time; Structure-Activity Relationship | 2002 |
[The influence of oxidizing agents on 4-dimethylamino-1-phenyl-2,3-dimethylpyrazole-5-one (pyramidon). Part 3. The splitting-off of formaldehyde from 4-dimethylamino-, from 4-amino-, or from 4-hydroxy-1-phenyl-2,3-dimethylpyrazolones].
Topics: Aminopyrine; Formaldehyde; Leadership; Oxidants | 1960 |
[Serum protein changes in formalin-arthritic rats under the action of antirheumatic agents].
Topics: Aminopyrine; Animals; Antirheumatic Agents; Arthritis, Experimental; Blood Proteins; Formaldehyde; Phenylbutazone; Rats | 1961 |