Page last updated: 2024-08-17

aminopyrine and dimethylnitrosamine

aminopyrine has been researched along with dimethylnitrosamine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199032 (88.89)18.7374
1990's3 (8.33)18.2507
2000's1 (2.78)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LaBar, J; Sander, J2
Sander, J; Walz, G1
Rao, GS1
Ishiwata, H; Ohno, Y; Omori, Y; Takahashi, A; Tanimura, A1
Eisenbrand, G; Kann, J; Klein, R; Preussmann, R; Spiegelhalder, B1
Burns, JJ; Conney, AH; Dashman, T; Kamm, JJ1
Mirvish, SS1
Gangolli, SD; Heading, CE; Lake, BG; Lloyd, AG; Phillips, JC1
Nakanishi, S; Nishiguchi, K; Serasinghe, P; Yamazaki, H1
Ermilov, VB; Il'nitskiĭ, AP; Iurchenko, VA; Zhukova, GF1
Eisenbrand, G; Schlemmer, KH1
Kosaka, H; Nakajima, T; Uozumi, M2
Archer, MC; Milligan, JR; Swann, PF; Zucker, PF1
Bartsch, H; Hietanen, E; Kobljakov, V1
Furman, MA; Mikhaĭlenko, VM1
Preussmann, R; Spiegelhalder, B2
Osin'kovskaia, ND; Rubenchik, BL2
Ziebarth, D1
Boĭm, TM; Rubenchik, BL; Tsapenko, VF1
Gombar, CT; Magee, PN; Strahan, GD; Zubroff, J1
Kasuya, Y; Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A1
Casciano, DA; Olson, MJ; Pounds, JG1
Adatia, MR; Osborn, JC; Rao, GS1
Neale, S; Solt, AK1
Bex, C; Cottrell, RC; Gangolli, SD; Lake, BG; Phillips, JC1
Kimura, T; Kusumoto, T; Nakajima, T; Nakamura, A; Uozumi, M1
Kasuya, Y; Kawanishi, T; Ohno, Y; Omori, Y; Onoda, K; Sunouchi, M; Takahashi, A1
Brambilla, G; Cavanna, M; Pala, M; Parodi, S; Taningher, M1
Hasegawa, MM; Inui, N; Nishi, Y; Taketomi, M; Tanimura, A; Yamamoto, M1
Deriagina, VP; Golubkina, NA; Khotimchenko, SA; Mamaeva, EM; Sokolov, AB; Vlaskina, SG; Zhukova, GF1
Artemov, KV; Galenko, PM; Glavin, AA; Kilkichko, AA; Oleinick, IO; Rubenchik, BL1
Doenhoff, MJ; Mostafa, MH; O'Connor, PJ; Rafferty, JA; Saeed, HM1

Reviews

1 review(s) available for aminopyrine and dimethylnitrosamine

ArticleYear
Blocking the formation of N-nitroso compounds with ascorbic acid in vitro and in vivo.
    Annals of the New York Academy of Sciences, 1975, Sep-30, Volume: 258

    Topics: Adenoma; Amines; Aminopyrine; Animals; Ascorbic Acid; Dimethylnitrosamine; Female; Liver; Lung Neoplasms; Mice; Morpholines; Neoplasms, Experimental; Nitrites; Nitrosamines; Nitroso Compounds; Pregnancy; Rats; Urea

1975

Other Studies

35 other study(ies) available for aminopyrine and dimethylnitrosamine

ArticleYear
Carcinogenic N-nitro-dimethylamine from the reaction of the analgesic amidopyrine and nitrite extracted from foodstuffs.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1975, Nov-25, Volume: 84, Issue:3

    Topics: Aminopyrine; Digestion; Dimethylnitrosamine; Food; Food Preservatives; Food-Processing Industry; Gastric Juice; Germany, West; Humans; Hydrogen-Ion Concentration; Legislation, Drug; Liver Neoplasms; Meat; Nitrites; Nitrosamines; Vegetables

1975
Screening for nitrosodimethylamine in human urine and experiments on the formation of this carcinogen from the analgesic amidopyrine in bacterial model systems.
    IARC scientific publications, 1976, Issue:14

    Topics: Aminopyrine; Ascorbic Acid; Bacteria; Dimethylnitrosamine; Escherichia coli; Glucose; Humans; Hydrogen-Ion Concentration; Models, Biological; Nitrites; Nitrosamines; Urea

1976
Nitrosation of drugs by human salivary nitrite.
    Archives of oral biology, 1978, Volume: 23, Issue:8

    Topics: Adult; Aminopyrine; Dimethylnitrosamine; Female; Humans; Male; Nitrites; Nitrosamines; Oxytetracycline; Saliva

1978
Drug-nitrite interactions: species and sex differences in the formation of dimethylnitrosamine and its effects on the hepatic enzyme activities.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1979, Issue:2

    Topics: Aminopyrine; Animals; Dimethylnitrosamine; Female; Gastric Mucosa; Guinea Pigs; Hexobarbital; Liver; Male; Nitrites; Nitrosamines; Rats; Sex Factors; Sleep; Species Specificity; Time Factors

1979
Carcinogenic N-nitrosodimethylamine as a contamination in drugs containing 4-dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one (amidopyrine, aminophenazone).
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:6

    Topics: Aminopyrine; Chemical Phenomena; Chemistry; Dimethylnitrosamine; Drug Contamination; Nitrogen Oxides

1979
Experiments on the detection of the carcinogenic N-nitroso-dimethylamine in the urine of rats after oral administration of the analgesic amidopyrine and nitrite.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:7

    Topics: Aminopyrine; Animals; Dimethylnitrosamine; Female; Nitrites; Nitrosamines; Rats

1976
Effect of ascorbic acid on amine-nitrite toxicity.
    Annals of the New York Academy of Sciences, 1975, Sep-30, Volume: 258

    Topics: Alanine Transaminase; Aminopyrine; Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Liver; Liver Diseases; Necrosis; Nitrites; Nitrosamines; Rats

1975
Studies on the metabolism of dimethylnitrosamine in the rat. II. The effects of phenobarbitone and 20-methylcholanthrene on the in vitro and in vivo metabolism and acute toxicity of dimethylnitrosamine in young and mature rats.
    Food and cosmetics toxicology, 1975, Volume: 13, Issue:6

    Topics: Age Factors; Aminopyrine; Aniline Hydroxylase; Animals; Carbon Dioxide; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ethylmorphine-N-Demethylase; Female; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Sex Factors

1975
Differential localization of microsomal mixed function oxidase activity in periportal and perivenous hepatocytes isolated from rat liver.
    The International journal of biochemistry, 1990, Volume: 22, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Coumarins; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Male; Microsomes, Liver; NADH Dehydrogenase; Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Inbred Strains

1990
[Assessment of the degree of carcinogenicity of small doses of nitrites].
    Voprosy onkologii, 1989, Volume: 35, Issue:7

    Topics: Aminopyrine; Animals; Carcinogens; Dimethylnitrosamine; Female; Food; Gastric Juice; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Morpholines; Nitrites; Nitrosamines; Sodium Nitrite; Water Supply

1989
Nitrosation of bromhexine and aminophenazone in gastric juice after high nitrate loading in the diet. An ex-vivo/in-vitro study in humans.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:9

    Topics: Aminopyrine; Bromhexine; Carcinogenicity Tests; Chromatography, Gas; Diet; Dimethylnitrosamine; Gastric Juice; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Nitrates; Nitrites; Nitrosamines; Saliva

1988
Induction of SOS functions in Escherichia coli and biosynthesis of nitrosamine in rabbits by nitrogen dioxide.
    Environmental health perspectives, 1987, Volume: 73

    Topics: Aminopyrine; Animals; Biotransformation; Cystamine; Dimethylnitrosamine; DNA Repair; Escherichia coli; Kinetics; Mutation; Nitrogen Dioxide; Nitrosamines; Operon; Plasmids; Rabbits; SOS Response, Genetics

1987
Absence of urinary N-nitrosodimethylamine in fasting humans following alcohol consumption.
    IARC scientific publications, 1987, Issue:84

    Topics: Adult; Alcohol Drinking; Aminopyrine; Biotransformation; Dimethylnitrosamine; Fasting; Humans; Male; Nitrates

1987
Role of different cytochrome P-450 isozymes in the demethylation of various substrates.
    General pharmacology, 1986, Volume: 17, Issue:5

    Topics: 1,2-Dimethylhydrazine; Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Dimethylhydrazines; Dimethylnitrosamine; In Vitro Techniques; Isoenzymes; Male; Metyrapone; Microsomes, Liver; Oxidoreductases, N-Demethylating; Proadifen; Rats; Substrate Specificity

1986
[Damage to the liver DNA of rats during the endogenous synthesis of N-nitrosodimethylamine].
    Eksperimental'naia onkologiia, 1986, Volume: 8, Issue:1

    Topics: Alkylation; Aminopyrine; Animals; Dimethylamines; Dimethylnitrosamine; DNA; DNA, Single-Stranded; Dose-Response Relationship, Drug; Liver; Male; Rats; Sodium Nitrite; Time Factors

1986
In vivo nitrosation of amidopyrine in humans: use of 'ethanol effect' for biological monitoring of N-nitrosodimethylamine in urine.
    Carcinogenesis, 1985, Volume: 6, Issue:4

    Topics: Aminopyrine; Dimethylnitrosamine; Ethanol; Humans; Nitrates; Nitrites; Saliva

1985
[Transplacental effect of sodium nitrite on rat lung cells with their subsequent culture in the medium with precursors of N-nitrosodimethylamine].
    Eksperimental'naia onkologiia, 1985, Volume: 7, Issue:2

    Topics: Aminopyrine; Animals; Ascorbic Acid; Cell Survival; Culture Media; Dimethylnitrosamine; Drug Synergism; Female; Fetus; In Vitro Techniques; Lung; Maternal-Fetal Exchange; Mitosis; Nitrites; Phenobarbital; Pregnancy; Pregnancy, Animal; Rats; Sodium Nitrite; Vitamin E

1985
[Formation of volatile carcinogenic N-nitroso compounds from drugs under simulated human gastric conditions].
    Archiv fur Geschwulstforschung, 1985, Volume: 55, Issue:5

    Topics: Aminopyrine; Amitriptyline; Clomiphene; Diethylamines; Diethylnitrosamine; Dimethylnitrosamine; Disulfiram; Doxycycline; Humans; Models, Biological; Nitroso Compounds; Oxytetracycline; Pharmaceutical Preparations; Probenecid; Stomach

1985
Measurement of nitrosodimethylamine by capillary gas chromatography-mass spectrometry with the 15N-labelled compound as an internal standard.
    International archives of occupational and environmental health, 1984, Volume: 54, Issue:3

    Topics: Aminopyrine; Animals; Dimethylnitrosamine; Gas Chromatography-Mass Spectrometry; Nitrogen Dioxide; Rabbits; Sulfur Oxides

1984
[Possibility of N-dimethylnitrosamine formation after parenteral administration of amidopyrine and nitrite to rats].
    Eksperimental'naia onkologiia, 1984, Volume: 6, Issue:3

    Topics: Aminopyrine; Animals; Ascorbic Acid; Dimethylnitrosamine; Injections, Intraperitoneal; Injections, Intravenous; Liver; Male; Necrosis; Nitrites; Phenobarbital; Rats

1984
[Biological characteristics of rat lung cells cultured in a medium with N-nitrosodimethylamine precursors].
    Eksperimental'naia onkologiia, 1984, Volume: 6, Issue:6

    Topics: Aminopyrine; Animals; Cell Division; Cells, Cultured; Dimethylnitrosamine; DNA; Lung; Mitotic Index; Rats; Sodium Nitrite

1984
In-vivo formation of N-nitrosodimethylamine in humans after amidopyrine intake.
    IARC scientific publications, 1984, Issue:57

    Topics: Aminopyrine; Dimethylnitrosamine; Humans; Nitrates; Nitrites; Saliva

1984
Measurement of 7-methylguanine as an estimate of the amount of dimethylnitrosamine formed following administration of aminopyrine and nitrite to rats.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Aminopyrine; Animals; Carbon Radioisotopes; Dimethylamines; Dimethylnitrosamine; DNA; Guanine; Kinetics; Liver; Male; Nitrites; Rats; Rats, Inbred Strains; Sodium Nitrite

1983
New method for quantitative measurement of N-nitrosodimethylamine formation in the whole mouse.
    Archives of toxicology, 1983, Volume: 54, Issue:4

    Topics: Aminopyrine; Animals; Chromatography, Gas; Dimethylnitrosamine; Dose-Response Relationship, Drug; Half-Life; Male; Mice; Pyrazoles; Sodium Nitrite

1983
Potentiation of dimethylnitrosamine genotoxicity in rat hepatocytes isolated following ethanol treatment in vivo.
    Chemico-biological interactions, 1984, Volume: 50, Issue:3

    Topics: Aminopyrine; Aniline Compounds; Animals; Dealkylation; Dimethylnitrosamine; DNA Repair; Drug Synergism; Ethanol; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Microsomes, Liver; Mutagens; Rats; Rats, Inbred F344

1984
Drug-nitrite interactions in human saliva: effects of food constituents on carcinogenic N-nitrosamine formation.
    Journal of dental research, 1982, Volume: 61, Issue:6

    Topics: Adult; Aminopyrine; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Female; Food; Humans; Male; Nitrites; Oxytetracycline; Saliva

1982
The effect of ascorbic acid on the amine-nitrite and nitrosamine mutagenicity in bacteria injected into mice.
    Chemico-biological interactions, 1981, Volume: 35, Issue:2

    Topics: Amines; Aminopyrine; Animals; Ascorbic Acid; Dimethylnitrosamine; Escherichia coli; Female; Mice; Mutagenicity Tests; Mutagens; Nitrites; Nitrosamines

1981
Inhibition of dimethylnitrosamine metabolism by some heterocyclic compounds and by substrates and inhibitors of monoamine oxidase in the rat.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Aminopyrine; Animals; Biogenic Amines; Biotransformation; Dimethylnitrosamine; Heterocyclic Compounds; Liver; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1982
Formation of N-nitrosodimethylamine by NOx exposure in rats and rabbit pretreated with aminopyrine.
    IARC scientific publications, 1982, Issue:41

    Topics: Aminopyrine; Animals; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Male; Nitrogen Dioxide; Rabbits; Rats; Rats, Inbred Strains

1982
Studies on nitrosamine formation by the interaction between drugs and nitrite. II. Hepatotoxicity by the simultaneous administration of several drugs and nitrite.
    The Journal of toxicological sciences, 1981, Volume: 6, Issue:4

    Topics: Aminopyrine; Animals; Antioxidants; Ascorbic Acid; Dimethylnitrosamine; Drug Interactions; Liver; Male; Nitrites; Nitrosamines; Rats; Rats, Inbred Strains

1981
Detection by alkaline elution of rat liver DNA damage induced by simultaneous subacute administration of nitrite and aminopyrine.
    Journal of toxicology and environmental health, 1980, Volume: 6, Issue:1

    Topics: Aminopyrine; Animals; Dimethylnitrosamine; DNA; Drug Interactions; Liver; Male; Nitrites; Rats

1980
Induction of 8-azaguanine-resistant mutation and neoplastic transformation of hamster embryonic cells by coadministration of sodium nitrite and aminopyrine.
    Journal of cancer research and clinical oncology, 1980, Volume: 97, Issue:2

    Topics: Abnormalities, Drug-Induced; Aminopyrine; Animals; Azaguanine; Cells, Cultured; Cricetinae; Dimethylnitrosamine; Female; In Vitro Techniques; Maternal-Fetal Exchange; Mutation; Neoplasms; Nitrites; Pregnancy; Sodium Nitrite

1980
[Effects of selenium on endogenous synthesis of N-nitrosamines and toxicity of nitrites in rats].
    Voprosy pitaniia, 1994, Issue:4

    Topics: Aminopyrine; Animal Feed; Animals; Biochemical Phenomena; Biochemistry; Dimethylnitrosamine; Male; Nitrites; Nitrosamines; Rats; Rats, Wistar; Selenium; Selenomethionine; Sodium Nitrite

1994
Gaseous nitrogen dioxide increases the endogenous synthesis of carcinogenic N-nitrosodimethylamine in animals.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1995, Volume: 14, Issue:2

    Topics: Administration, Inhalation; Administration, Oral; Alanine Transaminase; Aminopyrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Carcinogens; Dimethylnitrosamine; DNA Damage; Drug Combinations; Glutathione Transferase; Liver; Male; Mice; Mice, Inbred C57BL; Mutagens; Nitrogen Dioxide; Rats; Sodium Nitrite

1995
Evidence for the presence of active cytochrome P450 systems in Schistosoma mansoni and Schistosoma haematobium adult worms.
    FEBS letters, 2002, May-22, Volume: 519, Issue:1-3

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Cricetinae; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Activation; Ethylmorphine; Female; Formaldehyde; Immunoblotting; Male; Mice; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxazines; Rats; Schistosoma haematobium; Schistosoma mansoni; Substrate Specificity

2002