aminopyrine has been researched along with cyclosporine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Beckurts, KT; Lauterburg, BH | 1 |
| Grevel, J; Kahan, BD; Napoli, KL; Serino, F; Strobel, HW | 2 |
| Bastien, MC; Demers, C; Gascon-Barré, M; Provencher, SJ; Villeneuve, JP | 1 |
| AlbertÃ, JJ; Morales-Ibanez, O; Sentellas, S; Zanuy, M | 1 |
8 other study(ies) available for aminopyrine and cyclosporine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Effect of cyclosporine A on the demethylation of aminopyrine in rats in vivo.
Topics: Aminopyrine; Animals; Carbon Dioxide; Cyclosporine; Dealkylation; Female; Liver Function Tests; Prednisolone; Rats; Rats, Sprague-Dawley | 1995 |
Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity.
Topics: Aminopyrine; Animals; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Induction; Free Radical Scavengers; Ketoconazole; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley | 1994 |
Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition.
Topics: Aminopyrine; Animals; Carbon Tetrachloride; Catalase; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Erythromycin; Free Radicals; Ketoconazole; Lipid Peroxidation; Male; Proadifen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 1993 |
Effect of cyclosporine A on cytochrome P-450-mediated drug metabolism in the partially hepatectomized rat.
Topics: Aminopyrine; Animals; Biotransformation; Blotting, Northern; Caffeine; Carbon Radioisotopes; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Activation; Erythromycin; Hepatectomy; Isoenzymes; Liver Regeneration; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity | 1999 |
GSSG/GSH ratios in cryopreserved rat and human hepatocytes as a biomarker for drug induced oxidative stress.
Topics: Aminopyrine; Animals; Biomarkers; Cells, Cultured; Cryopreservation; Cyclosporine; Flutamide; Glutathione; Glutathione Disulfide; Hepatocytes; Humans; Male; Oxidative Stress; Rats, Sprague-Dawley; Tolmetin | 2014 |