Compounds > aminopterin
Page last updated: 2024-09-05

aminopterin and allopurinol

aminopterin has been researched along with allopurinol in 7 studies

Compound Research Comparison

Studies
(aminopterin)		Trials
(aminopterin)		Recent Studies (post-2010)
(aminopterin)		Studies
(allopurinol)		Trials
(allopurinol)		Recent Studies (post-2010) (allopurinol)
1,3897310915,0967433,363

Protein Interaction Comparison

ProteinTaxonomyaminopterin (IC50)allopurinol (IC50)
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase Rattus norvegicus (Norway rat)3.3765
Xanthine dehydrogenase/oxidaseHomo sapiens (human)3.1861
Xanthine dehydrogenase/oxidaseBos taurus (cattle)5.0758
Histamine H3 receptorCavia porcellus (domestic guinea pig)8.69

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Meany, JE; Pilot, TF; Robinson, K1
Tashima, CK1
Dempski, R; Hille, R; Xia, M1
AKASHI, A; HANO, K; IWATA, H1

Other Studies

7 other study(ies) available for aminopterin and allopurinol

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Time dependent inhibition of xanthine oxidase in irradiated solutions of folic acid, aminopterin and methotrexate.
    Physiological chemistry and physics and medical NMR, 1990, Volume: 22, Issue:2

    Topics: Aminopterin; Folic Acid; Kinetics; Methotrexate; Photolysis; Spectrophotometry; Time Factors; Ultraviolet Rays; Xanthine Oxidase

1990
Leukemia, drugs and ACTH.
    The New England journal of medicine, 1970, Mar-19, Volume: 282, Issue:12

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Allopurinol; Aminopterin; Busulfan; Humans; Leukemia, Myeloid; Mercaptopurine; Myeloproliferative Disorders; Pituitary-Adrenal System

1970
The reductive half-reaction of xanthine oxidase. Reaction with aldehyde substrates and identification of the catalytically labile oxygen.
    The Journal of biological chemistry, 1999, Feb-05, Volume: 274, Issue:6

    Topics: Aminopterin; Animals; Benzaldehydes; Binding Sites; Catalysis; Cattle; Gentisates; Hydroxybenzoates; Kinetics; Milk; Oxidation-Reduction; Oxygen; Substrate Specificity; Xanthine Oxidase

1999
Influences of anticancer agents on the activities of liver catalase, uricase, and xanthine oxidase in normal and tumor-bearing mice.
    Gan, 1963, Volume: 54

    Topics: Aminopterin; Animals; Antineoplastic Agents; Azaguanine; Carboxylic Acids; Carcinoma, Ehrlich Tumor; Catalase; Cyclopentanes; Liver; Mercaptopurine; Methotrexate; Mice; N-Glycosyl Hydrolases; Neoplasms; Oxidoreductases; Thiotepa; Urate Oxidase; Xanthine Oxidase

1963