Page last updated: 2024-09-05

aminopterin and 5-deazaaminopterin

aminopterin has been researched along with 5-deazaaminopterin in 5 studies

Compound Research Comparison

Studies
(aminopterin)
Trials
(aminopterin)
Recent Studies (post-2010)
(aminopterin)
Studies
(5-deazaaminopterin)
Trials
(5-deazaaminopterin)
Recent Studies (post-2010) (5-deazaaminopterin)
1,38973109500

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Montgomery, JA; Otter, GM; Piper, JR; Schmid, FA; Sirotnak, FM1
Chou, TC; Huang, JT; Otter, GM; Sirotnak, FM; Su, TL; Watanabe, KA1
Burchenal, JH; Fox, JJ; Huang, JT; Su, TL; Watanabe, KA1
Montgomery, JA; Morrison, JF; Stone, SR1
Colwell, WT; DeGraw, JI; Johnson, CA; Piper, JR; Sirotnak, FM; Smith, RL; Waud, WR1

Other Studies

5 other study(ies) available for aminopterin and 5-deazaaminopterin

ArticleYear
Structural design, biochemical properties, and evidence for improved therapeutic activity of 5-alkyl derivatives of 5-deazaaminopterin and 5-deazamethotrexate compared to methotrexate in murine tumor models.
    Cancer research, 1988, Oct-15, Volume: 48, Issue:20

    Topics: Adenocarcinoma; Alkylation; Aminopterin; Animals; Drug Compounding; Epithelium; Intestine, Small; Kinetics; Mammary Neoplasms, Experimental; Methotrexate; Mice; Sarcoma 180; Structure-Activity Relationship

1988
Chemical synthesis and biological activities of 5-deazaaminopterin analogues bearing substituent(s) at the 5- and/or 7-position(s).
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:6

    Topics: Aminopterin; Antineoplastic Agents; Humans; Methotrexate; Structure-Activity Relationship; Tumor Cells, Cultured

1988
Synthesis and biological activities of 5-deaza analogues of aminopterin and folic acid.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:5

    Topics: Aminopterin; Animals; Folic Acid; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Spectrophotometry, Ultraviolet

1986
Inhibition of dihydrofolate reductase from bacterial and vertebrate sources by folate, aminopterin, methotrexate and their 5-deaza analogues.
    Biochemical pharmacology, 1984, Jan-15, Volume: 33, Issue:2

    Topics: Aminopterin; Animals; Chickens; Escherichia coli; Folic Acid; Folic Acid Antagonists; Kinetics; Liver; Methotrexate; Protein Binding; Structure-Activity Relationship

1984
Analogues of methotrexate in rheumatoid arthritis. 2. Effects of 5-deazaaminopterin, 5,10-dideazaaminopterin, and analogues on type II collagen-induced arthritis in mice.
    Journal of medicinal chemistry, 1997, Jan-31, Volume: 40, Issue:3

    Topics: Aminopterin; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Survival; Collagen; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methotrexate; Mice; Mice, Inbred DBA; Molecular Structure; Tumor Cells, Cultured

1997