aminopropionitrile and elastin

aminopropionitrile has been researched along with elastin in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199052 (68.42)18.7374
1990's6 (7.89)18.2507
2000's5 (6.58)29.6817
2010's7 (9.21)24.3611
2020's6 (7.89)2.80

Authors

AuthorsStudies
DeGroot, JE; Harris, ED; Rayton, JK1
Murray, J; Rucker, RB1
Faris, B; Foster, JA; Franzblau, C; Imberman, M; Mecham, R1
Keeley, FW3
Berglund, N; Foster, JA; Huber, S; Lange, G; Mecham, RP; Rich, CB1
Jellinek, H; Joos, A; Kadar, A1
Foster, JA; Franzblau, C; Mecham, R1
Layman, DL; Narayanan, AS; Ross, R; Sandberg, LB1
Nakashima, Y; Sueishi, K1
Faris, B; Foster, JA; Franzblau, C; Jackson, LE; Jones, HV; Martin, BM; Rich, CB1
Hulmes, DJ; Shackleton, DR1
Capdeville, M; Coutard, M; Osborne-Pellegrin, MJ1
Rucker, RB; Tinker, D1
Contri, MB; Fornieri, C; Mori, G; Quaglino, D; Ronchetti, IP1
Contri, MB; Fornieri, CC; Ronchetti, IP1
Mitsuhashi, T; Shimazaki, M1
Blank, J; Burdette, L; Glasgow, JE; Pietra, GG; Weinbaum, G1
Bashey, R; Cox, RH; Jimenez, S1
Roach, MR; Terpin, T1
Berg, RA; Chae, CU; Kerr, JS; Kramer, MJ; Riley, DJ; Yu, SY1
Barone, LM; Chipman, SD; Faris, B; Franzblau, C; Pratt, CA1
Kádár, A1
McCrary, C; Orbison, JL1
Bihari-Varga, M; Biró, T; Lévai, J1
Wolinsky, H1
Layman, DL; Martin, GR; Narayanan, AS1
Harris, ED; O'Dell, BL1
Franzblau, C; Hewitt, NA; Kagan, HM; Salcedo, LL1
Barrow, MV; Miller, EJ; Simpson, CF1
Partridge, SM; Sykes, BC1
Anna, K; Harry, J1
Ledvina, M1
Allen, JR; Lalich, JJ; Paik, WC1
Benditt, EP; Page, RC2
Barrow, MV; Simpson, CF1
Martin, GR; Narayanan, AS; Siegel, RC1
Fyfe, FW; Gillman, T; Oneson, IB1
Faris, B; Franzblau, C; Salcedo, LL1
Martin, GR; Miller, EJ; Pinnell, SR1
Partridge, SM1
Martin, GR; Mecca, CE; Miller, EJ; Piez, KA1
Elsden, DF; O'Dell, BL; Palmer, R; Partridge, SM; Smith, RH; Thomas, J1
Herd, K; Orbison, JL1
Kuhn, C; Starcher, BC1
Langeveld, CH; Moskalewski, S; Scherft, JP1
Baccarani-Contri, M; Bressan, GM; Castellani, I; Fornieri, C; Pasquali-Ronchetti, I; Volpin, D1
Foster, JA; Rich, CB1
Hoidal, JR; Niewoehner, DE1
Bressan, GM; Castellani, I; Fornieri, C; Pasquali-Ronchetti, I; Volpin, D1
Adam, M; Deyl, Z; Macek, K1
Das, RM1
Fukuda, Y; Nakazawa, N; Yamanaka, N1
Harvey, CS; Liu, R; McGowan, SE1
Mańkowska, E; Moskalewski, S; Osiecka-Iwan, A1
BENTLEY, JP; WIRTSCHAFTER, ZT1
Guo, Y; Jeay, S; Palamakumbura, AH; Pischon, N; Sommer, P; Sonenshein, GE; Trackman, PC1
Bollinger, JA; Csiszar, K; Dooley, DM; Fogelgren, B; Fong, SF; Mink, M; Molnar, J; Ujfaludi, Z; Waro, G1
Addad, F; Al Haj Zen, A; Bellon, G; Bouthors, S; Brasselet, C; de Kleijn, D; Durand, E; Garnotel, R; Godeau, G; Gogly, B; Lafont, A; Laurent-Maquin, D; Smeets, MB1
Di Donato, A; Gastaldo, N; Oleggini, R1
Challande, P; Kakou, A; Lacolley, P; Mercier, N; Osborne-Pellegrin, M1
Kim, EC; Kim, Y; Kim, YM1
Hammer, CM; Hofmann-Rummelt, C; Kruse, FE; Krysta, AW; Pasutto, F; Sasaki, T; Schlötzer-Schrehardt, U; Zenkel, M1
Chang, YT; Chen, JY; Chiou, YW; Chou, CH; Lam, CF; Li, YH; Lin, LJ; Shiesh, SC; Tai, HC; Tang, MJ; Tsai, PJ; Tsai, RL; Tsai, WC; Tsai, YS; Wang, MC; Wu, HL; Yeh, ML1
Brinckmann, J; Herold, S; Madurga, A; Mayer, K; Mižíková, I; Morty, RE; Ruiz-Camp, J; Seeger, W; Steenbock, H; Vadász, I1
Chesler, NC; Eickhoff, JC; Eliceiri, KW; Liu, Y; Tian, L; Wang, Z1
Chen, B; Du, J; Jia, L; Li, P; Li, Y; Liu, C; Liu, L; Sun, J; You, B; Zhang, C; Zhang, W1
Chuma, M; Fujino, H; Fukushima, K; Horinouchi, Y; Ikeda, Y; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kohara, Y; Sairyo, E; Sakurada, T; Takechi, K; Tamaki, T; Tsuchiya, K; Yoshizumi, M; Zamami, Y1
Chu, YX; Guo, LL; Jing, ZP; Li, JS; Sun, YD; Tian, P; Wu, MT; Yeung, KK; Zhang, L; Zhang, LW1
Berman, AG; Cavinato, C; Goergen, CJ; Humphrey, JD; Latorre, M; Rego, BV; Tanski, BJ; Weiss, D1
Ding, YC; Jiang, BH; Zhai, ZY; Zhang, JX; Zhang, MX; Zhang, XJ1
Bai, H; Dardik, A; Sun, P; Wei, S; Xing, Y; Zhang, L1
Cai, DP; Chen, SY; Guo, D; Luo, BY; Tian, Q; Wang, HJ; Xie, WB; Xu, ZZ; Yang, Q; Zhou, J; Zhou, RM1
Chen, D; Gao, S; Ge, S; Luo, J; Niu, K; Ren, M; Shao, Y; Wang, X; Wu, Q; Xiao, Q; Yang, M; Yang, Z; Zhang, C; Zhou, X1

Reviews

6 review(s) available for aminopropionitrile and elastin

ArticleYear
Cross-linking amino acids in collagen and elastin.
    The American journal of clinical nutrition, 1978, Volume: 31, Issue:7

    Topics: Amino Acid Sequence; Amino Acids; Aminopropionitrile; Animals; Chemical Phenomena; Chemistry; Collagen; Copper; Desmosine; Elastin; Humans; Hydroxylysine; Lysine; Metabolism, Inborn Errors; Nutrition Disorders; Nutritional Physiological Phenomena; Penicillamine; Protein-Lysine 6-Oxidase; Tropocollagen

1978
Role of selected nutrients in synthesis, accumulation, and chemical modification of connective tissue proteins.
    Physiological reviews, 1985, Volume: 65, Issue:3

    Topics: Aminopropionitrile; Animals; Ascorbic Acid; Collagen; Connective Tissue; Copper; Cross-Linking Reagents; Diet; Dietary Proteins; Drug Interactions; Elastin; Energy Intake; Extracellular Matrix; Flavonoids; Genes; Homocysteine; Lathyrism; Manganese; Monoamine Oxidase Inhibitors; Nutritional Physiological Phenomena; Penicillamine; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Procollagen-Proline Dioxygenase; Protein Biosynthesis; Protein-Lysine 6-Oxidase; Proteins; Proteoglycans; Pyridoxine; Riboflavin; Thiamine; Vitamin A; Vitamin D; Vitamin E; Vitamin K; Vitamins; Zinc

1985
[Pathophysiological mechanism of emphysematous bullae and blebs].
    Kokyu to junkan. Respiration & circulation, 1987, Volume: 35, Issue:10

    Topics: Aminopropionitrile; Animals; Blister; Carrageenan; Collagen; Elastin; Humans; Pulmonary Emphysema

1987
Mesenchymal response of the blood vessel wall. A potential avenue for understanding and treating atherosclerosis.
    Circulation research, 1973, Volume: 32, Issue:5

    Topics: Aminopropionitrile; Androgens; Animals; Arteriosclerosis; Blood Vessels; Cell Differentiation; Cholesterol; Collagen; Cyproterone; Elastin; Estrogens; Glycosaminoglycans; Humans; Hyperlipidemias; Hypertension; Muscle, Smooth; Rabbits; Rats

1973
Lathyrism: a review.
    The Quarterly review of biology, 1974, Volume: 49, Issue:2

    Topics: Abnormalities, Drug-Induced; Amino Acid Oxidoreductases; Aminopropionitrile; Aneurysm; Animals; Aortic Aneurysm; Blood Vessels; Bone and Bones; Bone Diseases; Cleft Palate; Collagen; Connective Tissue; Elastin; Fetus; Heart Defects, Congenital; Humans; Kyphosis; Lathyrism; Lysine; Neurologic Manifestations; Nitriles; Poultry Diseases; Rodent Diseases; Spinal Cord; Spinal Cord Diseases; Stomach; Turkeys

1974
[Oblique bindings in elastin and their developmental changes].
    Ceskoslovenska fysiologie, 1968, Volume: 17, Issue:5

    Topics: Age Factors; Aminopropionitrile; Animals; Arteriosclerosis; Chemical Phenomena; Chemistry, Physical; Elastin; Lathyrism; Leucine; Molecular Weight; Protein Binding

1968

Other Studies

70 other study(ies) available for aminopropionitrile and elastin

ArticleYear
A critical role for copper in aortic elastin structure and synthesis.
    Advances in experimental medicine and biology, 1977, Volume: 79

    Topics: Aminopropionitrile; Animals; Aorta; Ceruloplasmin; Chickens; Copper; Cycloheximide; Dactinomycin; Elastin; Enzyme Activation; Microscopy, Electron, Scanning; Protein-Lysine 6-Oxidase; Swine

1977
A high molecular weight species of soluble elastin-proelastin.
    Advances in experimental medicine and biology, 1977, Volume: 79

    Topics: Amino Acid Sequence; Amino Acids; Aminopropionitrile; Animals; Chickens; Circular Dichroism; Collagen; Elastin; Epitopes; Lathyrism; Microscopy, Electron; Models, Biological; Molecular Weight; Oxidation-Reduction; Protein Precursors; Solubility; Tropoelastin

1977
A convenient method for the identification and estimation of soluble elastin synthesis in vitro.
    Connective tissue research, 1976, Volume: 4, Issue:3

    Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Carbon Radioisotopes; Chick Embryo; Collagen; Elastin; Electrophoresis, Polyacrylamide Gel; Hydroxyproline; Methods; Molecular Weight; Proline; Protein Denaturation; Valine

1976
The anti-proteolytic behavior of lathyrogens.
    Biochimica et biophysica acta, 1979, Nov-01, Volume: 587, Issue:4

    Topics: Acetonitriles; Aminoacetonitrile; Aminopropionitrile; Animals; Benzoylarginine Nitroanilide; Binding, Competitive; Chick Embryo; Chickens; Chymotrypsin; Elastin; Fumarates; Pancreatic Elastase; Protease Inhibitors; Tropoelastin; Trypsin; Trypsin Inhibitors

1979
The synthesis of soluble and insoluble elastin in chicken aorta as a function of development and age. Effect of a high cholesterol diet.
    Canadian journal of biochemistry, 1979, Volume: 57, Issue:11

    Topics: Aging; Aminopropionitrile; Animals; Aorta; Chick Embryo; Chickens; Cholesterol; Cholesterol, Dietary; DNA; Elastin; Female

1979
Influence of beta-amino-propionitrile on elastogenesis in the chick embryo (light and electron microscopic study).
    Paroi arterielle, 1978, Volume: 4, Issue:3

    Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Aortic Rupture; Chick Embryo; Elastic Tissue; Elastin; Phosphotungstic Acid

1978
Proteolysis of tropoelastin.
    Advances in experimental medicine and biology, 1977, Volume: 79

    Topics: Aminopropionitrile; Animals; Chelating Agents; Chickens; Elastin; Endopeptidases; Molecular Weight; Pancreatic Elastase; Protease Inhibitors; Protein Binding; Sulfhydryl Reagents; Tosylarginine Methyl Ester; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Tropoelastin

1977
Detection and estimation of newly synthesized soluble elastin using a hydroxyproline label.
    Advances in experimental medicine and biology, 1977, Volume: 79

    Topics: 2,2'-Dipyridyl; Aminopropionitrile; Animals; Aorta; Chick Embryo; Collagen; Elastin; Hydroxylation; Hydroxyproline; Molecular Weight; Nitrogen; Phenanthrolines; Solubility; Time Factors; Valine

1977
The smooth muscle cell. III. Elastin synthesis in arterial smooth muscle cell culture.
    The Journal of cell biology, 1976, Volume: 68, Issue:3

    Topics: Aminopropionitrile; Cells, Cultured; Desmosine; Elastin; Lysine; Muscle, Smooth; Tropoelastin

1976
Alteration of elastic architecture in the lathyritic rat aorta implies the pathogenesis of aortic dissecting aneurysm.
    The American journal of pathology, 1992, Volume: 140, Issue:4

    Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Body Weight; Elastic Tissue; Elastin; Glycosaminoglycans; Hypertension; Lathyrism; Male; Rats; Rats, Inbred Strains

1992
The effect of beta-aminopropionitrile on elastin gene expression in smooth muscle cell cultures.
    Biochemical and biophysical research communications, 1991, Sep-16, Volume: 179, Issue:2

    Topics: Aminopropionitrile; Animals; Blotting, Northern; Cells, Cultured; Elastin; Gene Expression Regulation; Muscle, Smooth, Vascular; Peptide Fragments; Protein-Lysine 6-Oxidase; Rats; Rats, Inbred Strains; RNA, Messenger; Tropoelastin

1991
An ultrafiltration assay for lysyl oxidase.
    Analytical biochemistry, 1990, Volume: 185, Issue:2

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Chick Embryo; Chickens; Dose-Response Relationship, Drug; Elastin; Protein-Lysine 6-Oxidase; Swine; Tritium; Ultrafiltration; Urea

1990
Spontaneous rupture of the internal elastic lamina in the rat: the manifestation of a genetically determined factor which may be linked to vascular fragility.
    Blood vessels, 1989, Volume: 26, Issue:4

    Topics: Aminopropionitrile; Aneurysm; Animals; Connective Tissue Diseases; Elastic Tissue; Elastin; Female; Hypertension; Longevity; Male; Protein-Lysine 6-Oxidase; Rats; Rats, Inbred BN; Rupture, Spontaneous; Species Specificity; Vascular Diseases

1989
Alterations of elastin fibrogenesis by inhibition of the formation of desmosine crosslinks. Comparison between the effect of beta-aminopropionitrile (beta-APN) and penicillamine.
    Connective tissue research, 1985, Volume: 14, Issue:2

    Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Chickens; Cross-Linking Reagents; Desmosine; Elastin; Glycosaminoglycans; Lathyrism; Microscopy, Electron; Penicillamine; Tropoelastin

1985
Elastin-proteoglycans association revealed by cytochemical methods.
    Connective tissue research, 1985, Volume: 13, Issue:3

    Topics: Aminopropionitrile; Animals; Aorta; Chickens; Elastic Tissue; Elastin; Glycosaminoglycans; Histocytochemistry; Lathyrism; Proteoglycans

1985
Nitrogen-dioxide-induced emphysema in rats. Lack of worsening by beta-aminopropionitrile treatment.
    The American review of respiratory disease, 1988, Volume: 137, Issue:2

    Topics: Aminopropionitrile; Analysis of Variance; Animals; Diet; Disease Models, Animal; Elastin; Germ-Free Life; Lathyrism; Lung; Male; Nitrogen Dioxide; Organ Size; Pulmonary Emphysema; Rats; Rats, Inbred Strains; Time Factors

1988
Effects of chronic beta-aminoproprionitrile treatment on rat carotid artery.
    Blood vessels, 1988, Volume: 25, Issue:2

    Topics: Administration, Oral; Aminopropionitrile; Animals; Blood Pressure; Body Weight; Carotid Arteries; Collagen; Dose-Response Relationship, Drug; Elastin; Rats; Vasoconstriction

1988
A biophysical and histological analysis of factors that lead to aortic rupture in normal and lathyritic turkeys.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:3

    Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Rupture; Brachiocephalic Trunk; Collagen; Elasticity; Elastin; Lathyrism; Male; Poultry Diseases; Turkeys

1987
Damage and repair of lung connective tissue in rats exposed to toxic levels of oxygen.
    The American review of respiratory disease, 1987, Volume: 135, Issue:2

    Topics: Aging; Aminopropionitrile; Animals; Biomechanical Phenomena; Body Weight; Bronchi; Collagen; Connective Tissue; Elastin; Emphysema; Lung; Male; Oxygen; Proteins; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Therapeutic Irrigation; Wound Healing

1987
Processing of soluble elastin in cultured neonatal rat smooth muscle cells.
    The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23

    Topics: Aminopropionitrile; Animals; Animals, Newborn; Aorta; Cells, Cultured; Elastin; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Kinetics; Molecular Weight; Muscle, Smooth, Vascular; Peptide Fragments; Protein Precursors; Rats; Tropoelastin

1985
The ultrastructure of elastic tissue.
    Pathologia Europaea, 1974, Volume: 9, Issue:2

    Topics: Age Factors; Aminopropionitrile; Animals; Aorta; Cattle; Chick Embryo; Collagen; Copper; Elastic Tissue; Elastin; Femoral Artery; Glucosamine; Glycoproteins; Glycosaminoglycans; Histocytochemistry; Humans; Microscopy, Electron; Muscle, Smooth; Myofibrils; Pancreatic Elastase; Polysaccharides; Proteins; Staining and Labeling; Swine

1974
Sulfate metabolism in lathyrism and aging.
    Laboratory investigation; a journal of technical methods and pathology, 1971, Volume: 25, Issue:4

    Topics: Aging; Aminopropionitrile; Animals; Aorta; Brain; Cartilage; Collagen; Elastin; Glycosaminoglycans; Lathyrism; Liver; Male; Rats; Rats, Inbred Strains; Sulfates; Sulfur Isotopes

1971
Changes in the thermal decomposition of aorta, tendon and articular cartilage in experimental lathyrism.
    Gerontologia, 1971, Volume: 17, Issue:3

    Topics: Aminopropionitrile; Animals; Aorta; Cartilage, Articular; Collagen; Elastin; Fumarates; Glycosaminoglycans; Hot Temperature; Lathyrism; Rabbits; Tendons; Tissue Extracts

1971
The production of lysyl oxidase by human fibroblasts in culture.
    Archives of biochemistry and biophysics, 1972, Volume: 149, Issue:1

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Carbon Isotopes; Cartilage; Cells, Cultured; Chickens; Collagen; Culture Media; Ehlers-Danlos Syndrome; Elastin; Fibroblasts; Humans; Lysine; Marfan Syndrome; Procollagen-Proline Dioxygenase; Proline; Skin; Tritium

1972
Copper and amine oxidases in connective tissue metabolism.
    Advances in experimental medicine and biology, 1974, Volume: 48, Issue:0

    Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Benzyl Compounds; Binding Sites; Cattle; Chickens; Chromatography, DEAE-Cellulose; Collagen; Connective Tissue; Copper; Diet; Elastin; Electrophoresis, Disc; Lathyrism; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Swine; Tendons

1974
Catalytic activity of aortic lysyl oxidase in an insoluble enzyme-substrate complex.
    Biochimica et biophysica acta, 1974, Sep-13, Volume: 365, Issue:1

    Topics: Amino Acid Oxidoreductases; Amino Acids; Aminopropionitrile; Animals; Antimetabolites; Aorta; Binding Sites; Borohydrides; Cartilage; Cattle; Chelating Agents; Chick Embryo; Dogs; Elastin; Female; Fetus; Hydrogen-Ion Concentration; Isotope Labeling; Kinetics; Lysine; Pregnancy; Protein Binding; Solubility; Temperature; Time Factors; Tritium

1974
Isolation of a soluble elastin from lathyritic chicks.
    The Biochemical journal, 1972, Volume: 130, Issue:4

    Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Chickens; Elastin; Electrophoresis; Iodine Isotopes; Lathyrism

1972
[Inhibition of elastic fiber formation by beta-aminopropionitrile (electron microscopic study)].
    Morphologiai es igazsagugyi orvosi szemle, 1973, Volume: 13, Issue:2

    Topics: Aminopropionitrile; Animals; Chick Embryo; Elastic Tissue; Elastin; Lathyrism; Microscopy, Electron; Muscle, Smooth

1973
Production of arterial hemosiderosis in rhesus monkeys following the ingestion of -aminopropionitrile.
    Laboratory investigation; a journal of technical methods and pathology, 1971, Volume: 25, Issue:4

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Arteries; Body Weight; Collagen; Disease Models, Animal; Edema; Elastin; Female; Ferrocyanides; Haplorhini; Hemorrhage; Hemosiderosis; Iliac Artery; Lathyrism; Macaca; Male; Sternum; Thoracic Arteries

1971
Diseases of connective and vascular tissues. IV. The molecular basis for lathyrism.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 26, Issue:1

    Topics: Acetaldehyde; Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Carbon Isotopes; Collagen; Collagen Diseases; Cyanides; Elastin; Lathyrism; Lysine; Metabolism, Inborn Errors; Protein Binding; Protein Denaturation; Rats

1972
Caution against the use of lathyrogens.
    Surgery, 1972, Volume: 71, Issue:2

    Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Aneurysm; Animals; Arteriosclerosis; Bone Diseases; Collagen; Elastin; Female; Humans; Joint Diseases; Lathyrism; Paralysis; Pregnancy; Wound Healing

1972
On the inhibition of lysyl oxidase by -aminopropionitrile.
    Biochemical and biophysical research communications, 1972, Jan-31, Volume: 46, Issue:2

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Carbon Isotopes; Cartilage; Chick Embryo; Chromatography, Gel; Collagen; Dialysis; Elastin; Kinetics; Lysine; Protein Binding; Tritium

1972
A combined quantitative chemical, light, and electron microscope study of aortic development in normal and nitrile-treated mice. Possible implications for elucidating nitrile-induced aortic lesions and regarding the genesis of spontaneous arterial lesions
    Annals of the New York Academy of Sciences, 1968, Nov-21, Volume: 149, Issue:2

    Topics: Aminopropionitrile; Animals; Aorta; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Collagen; Depression, Chemical; Elastin; Female; Fetal Diseases; Fetus; Hydroxyproline; Mice; Microscopy, Electron; Nitriles; Pregnancy; Pregnancy, Animal

1968
Studies on the reduction of elastin. Biosynthesis and stability of the aldol condensation product of alpha-aminoadipic acid-delta-semialdehyde.
    Biochimica et biophysica acta, 1969, Volume: 188, Issue:2

    Topics: Adipates; Aldehydes; Amino Acids; Aminopropionitrile; Animals; Aorta; Autoanalysis; Boron Compounds; Carbon Isotopes; Cattle; Chick Embryo; Culture Techniques; Depression, Chemical; Elastin; Hydrogen-Ion Concentration; Ligaments; Lysine; Pancreatic Elastase; Time Factors; Tritium

1969
Desmosine biosynthesis: nature of inhibition by D-penicillamine.
    Science (New York, N.Y.), 1968, Aug-02, Volume: 161, Issue:3840

    Topics: Adipates; Amino Acids; Aminopropionitrile; Animals; Aorta; Chick Embryo; Collagen; Connective Tissue; Depression, Chemical; Elastin; Lathyrism; Lysine; Penicillamine; Peptide Biosynthesis

1968
Elastin, biosynthesis and structure.
    Gerontologia, 1969, Volume: 15, Issue:2

    Topics: Aldehydes; Aminopropionitrile; Animals; Cattle; Chemical Phenomena; Chemistry; Chickens; Copper; Ducks; Elastin; Lysine; Peptide Biosynthesis; Pyridinium Compounds; Rats

1969
The biosynthesis of elastin cross-links. The effect of copper deficiency and a lathyrogen.
    The Journal of biological chemistry, 1965, Volume: 240, Issue:9

    Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Chick Embryo; Copper; Culture Techniques; Cyanides; Deficiency Diseases; Elastic Tissue; Elastin; Lathyrism; Lysine; Penicillamine

1965
Inhibition of the biosynthesis of the cross-links in elastin by a lathyrogen.
    Nature, 1966, Jan-22, Volume: 209, Issue:5021

    Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Cyanides; Elastin; Fumarates; Lysine; Poultry; Pyridines

1966
Lathyrism in the fetal rat. Evidence for impairment of elastin formation.
    Archives of pathology, 1966, Volume: 81, Issue:1

    Topics: Aminopropionitrile; Animals; Congenital Abnormalities; Cyanides; Elastin; Female; Fetal Death; Fetal Diseases; Lathyrism; Pregnancy; Rats

1966
Interaction of the lathyrogen beta-aminopropionitrile (BAPN) with a copper-containing amine oxidase.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:2

    Topics: Aminopropionitrile; Collagen; Connective Tissue; Cyanides; Elastin; Enzymes; Oxidoreductases; Spectrophotometry

1967
The effect of lathyrogens on the evolution of elastase-induced emphysema.
    The American review of respiratory disease, 1980, Volume: 122, Issue:3

    Topics: Aminopropionitrile; Animals; Collagen; Cricetinae; Desmosine; Elastin; Lung; Mesocricetus; Pancreatic Elastase; Penicillamine; Protein-Lysine 6-Oxidase; Pulmonary Emphysema

1980
Influence of beta-aminoproprionitrile (BAPN) on cell growth and elastic fiber formation in cultures of auricular chondrocytes.
    Experientia, 1983, Oct-15, Volume: 39, Issue:10

    Topics: Aminopropionitrile; Animals; Cartilage; Cell Division; Cells, Cultured; Elastin; Rabbits

1983
Elastin fiber-associated glycosaminoglycans in beta-aminopropionitrile-induced lathyrism.
    Experimental and molecular pathology, 1984, Volume: 40, Issue:2

    Topics: Aminopropionitrile; Animals; Aorta; Chickens; Chondroitinases and Chondroitin Lyases; Collagen; Dermatan Sulfate; Elastin; Glycosaminoglycans; Guanidine; Guanidines; Heparitin Sulfate; Hyaluronoglucosaminidase; Lathyrism; Nitrous Acid; Polysaccharide-Lyases

1984
Isolation of soluble elastin-lathyrism.
    Methods in enzymology, 1982, Volume: 82 Pt A

    Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Cartilage; Chickens; Elastin; Lathyrism; Lung; Methods; Swine; Tropoelastin

1982
Lung fibrosis and emphysema: divergent responses to a common injury?
    Science (New York, N.Y.), 1982, Jul-23, Volume: 217, Issue:4557

    Topics: Aminopropionitrile; Animals; Cadmium; Cadmium Chloride; Collagen; Connective Tissue; Cricetinae; Elastin; Female; Intubation, Intratracheal; Lung; Mesocricetus; Pulmonary Emphysema; Pulmonary Fibrosis

1982
Alterations of the connective tissue components induced by beta-aminopropionitrile.
    Experimental and molecular pathology, 1981, Volume: 35, Issue:1

    Topics: Amino Acids; Aminopropionitrile; Animals; Aorta; Chickens; Collagen; Connective Tissue; Elastin; Extracellular Space; Lathyrism; Lung; Skin

1981
3-Hydroxypyridinium cross-links in lathyritic tissues.
    Biochemical and biophysical research communications, 1981, Aug-14, Volume: 101, Issue:3

    Topics: Amino Acids; Aminopropionitrile; Animals; Chemical Phenomena; Chemistry; Collagen; Elastin; Hydrazines; Lathyrism; Male; Oxalates; Penicillamine; Pyridinium Compounds; Rats; Rats, Inbred Strains; Semicarbazides

1981
The effect of beta-aminopropionitrile on lung development in the rat.
    The American journal of pathology, 1980, Volume: 101, Issue:3

    Topics: Aminopropionitrile; Animals; DNA; Elastic Tissue; Elastin; Lung; Male; Organoids; Pulmonary Alveoli; Rats

1980
Interactions of elastin and microfibrils in elastogenesis of human pulmonary fibroblasts in culture.
    Connective tissue research, 1993, Volume: 29, Issue:4

    Topics: Aminopropionitrile; Cell Line; Elastin; Embryo, Mammalian; Extracellular Matrix; Fibroblasts; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Lung; Microscopy, Immunoelectron; Protein-Lysine 6-Oxidase; Resorcinols; Rosaniline Dyes; Staining and Labeling

1993
Effects of heparin and other glycosaminoglycans on elastin production by cultured neonatal rat lung fibroblasts.
    Archives of biochemistry and biophysics, 1993, Volume: 302, Issue:2

    Topics: Aminopropionitrile; Animals; Animals, Newborn; Cells, Cultured; Chondroitin Sulfates; Dermatan Sulfate; Elastin; Extracellular Matrix; Fibroblasts; Glycosaminoglycans; Heparin; Lung; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepharose; Solubility; Tropoelastin

1993
Formation of lamellar bone on the surface of woven bone is not prevented by BAPN.
    Folia histochemica et cytobiologica, 1996, Volume: 34, Issue:2

    Topics: Aminopropionitrile; Animals; Bone and Bones; Bone Development; Collagen; Elastin; Female; Male; Mice; Mice, Inbred Strains

1996
EXTRACTABLE COLLAGEN IN THE NORMAL AND ANEURYSMAL AORTA: STUDIES IN LATHYRISM.
    Archives of pathology, 1965, Volume: 79

    Topics: Aminopropionitrile; Aorta; Aortic Aneurysm; Chemical Phenomena; Chemistry; Collagen; Cyanides; Elastin; Histological Techniques; Lathyrism; Pathology; Rats; Research

1965
The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells.
    The Journal of biological chemistry, 2004, Sep-24, Volume: 279, Issue:39

    Topics: Aminopropionitrile; Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line, Transformed; Collagen; Elastin; Genetic Vectors; Luciferases; Mice; Microscopy, Fluorescence; NF-kappa B; NIH 3T3 Cells; Oligonucleotides, Antisense; Peptides; Phenotype; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Lysine 6-Oxidase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Suramin; Time Factors; Transfection

2004
Drosophila lysyl oxidases Dmloxl-1 and Dmloxl-2 are differentially expressed and the active DmLOXL-1 influences gene expression and development.
    The Journal of biological chemistry, 2005, Jun-17, Volume: 280, Issue:24

    Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Aminopropionitrile; Animals; Animals, Genetically Modified; Blotting, Northern; Catalysis; Cell Differentiation; Cell Line; Cell Membrane; Cell Movement; Cell Nucleus; Chromatin; Chromosome Mapping; Collagen; Cytoplasm; DNA Primers; DNA, Complementary; Down-Regulation; Drosophila melanogaster; Elastin; Euchromatin; Extracellular Matrix; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Genome; Immunohistochemistry; Microscopy, Confocal; Models, Genetic; Molecular Sequence Data; Muscle, Smooth; Polymerase Chain Reaction; Protein Structure, Tertiary; Protein-Lysine 6-Oxidase; Recombinant Proteins; RNA, Messenger; Saliva; Salivary Glands; Sequence Homology, Amino Acid; Transcription, Genetic

2005
Collagen and elastin cross-linking: a mechanism of constrictive remodeling after arterial injury.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:5

    Topics: Aminopropionitrile; Angiography; Animals; Arteries; Atherosclerosis; Catheterization; Collagen; Coronary Restenosis; Elastin; Enzyme Inhibitors; Extracellular Matrix; Femoral Artery; Microscopy, Electron, Transmission; Protein-Lysine 6-Oxidase; Rabbits

2005
Regulation of elastin promoter by lysyl oxidase and growth factors: cross control of lysyl oxidase on TGF-beta1 effects.
    Matrix biology : journal of the International Society for Matrix Biology, 2007, Volume: 26, Issue:6

    Topics: Aminopropionitrile; Binding Sites; Cell Line; Connective Tissue Growth Factor; Elastin; Electrophoretic Mobility Shift Assay; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Luciferases; Mutation; Promoter Regions, Genetic; Protein Binding; Protein-Lysine 6-Oxidase; Recombinant Fusion Proteins; Smad Proteins; Smad3 Protein; Smad4 Protein; Transfection; Transforming Growth Factor beta1; Tropoelastin

2007
Comparison of the effects of semicarbazide and beta-aminopropionitrile on the arterial extracellular matrix in the Brown Norway rat.
    Toxicology and applied pharmacology, 2009, Sep-15, Volume: 239, Issue:3

    Topics: Amine Oxidase (Copper-Containing); Aminopropionitrile; Animals; Aorta, Thoracic; Body Weight; Carotid Arteries; Collagen; Drug Synergism; Elastin; Extracellular Matrix; Male; Pilot Projects; Protein-Lysine 6-Oxidase; Rats; Rats, Inbred BN; Semicarbazides

2009
The human lysyl oxidase-like 2 protein functions as an amine oxidase toward collagen and elastin.
    Molecular biology reports, 2011, Volume: 38, Issue:1

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Cattle; Collagen; Elastin; Escherichia coli; Humans; Oxidoreductases Acting on CH-NH2 Group Donors; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity

2011
LOXL1 deficiency in the lamina cribrosa as candidate susceptibility factor for a pseudoexfoliation-specific risk of glaucoma.
    Ophthalmology, 2012, Volume: 119, Issue:9

    Topics: Aged; Aged, 80 and over; Amino Acid Oxidoreductases; Aminopropionitrile; Astrocytes; Cells, Cultured; Collagen; Disease Progression; Disease Susceptibility; Elastic Tissue; Elastin; Enzyme Inhibitors; Exfoliation Syndrome; Extracellular Matrix; Extracellular Matrix Proteins; Female; Fibrillin-1; Fibrillins; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation, Enzymologic; Glaucoma, Open-Angle; Humans; Male; Microfilament Proteins; Optic Disk; Real-Time Polymerase Chain Reaction; Risk Factors; Tissue Donors; Transforming Growth Factor beta1

2012
Increased aortic stiffness and attenuated lysyl oxidase activity in obesity.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:4

    Topics: Adipocytes; Adipose Tissue; Adult; Aminopropionitrile; Animals; Aorta, Abdominal; Case-Control Studies; Cell Line; Culture Media, Conditioned; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Elastic Modulus; Elastin; Enzyme Inhibitors; Female; Humans; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Middle Aged; Obesity; Oxidative Stress; Protein-Lysine 6-Oxidase; Pulse Wave Analysis; Time Factors; Vascular Stiffness

2013
Collagen and elastin cross-linking is altered during aberrant late lung development associated with hyperoxia.
    American journal of physiology. Lung cellular and molecular physiology, 2015, Jun-01, Volume: 308, Issue:11

    Topics: Aminopropionitrile; Animals; Bronchopulmonary Dysplasia; Collagen; Elastin; Extracellular Matrix; Hyperoxia; Lung; Mice; Protein Processing, Post-Translational; Protein-Lysine 6-Oxidase

2015
Validation of an arterial constitutive model accounting for collagen content and crosslinking.
    Acta biomaterialia, 2016, Volume: 31

    Topics: Aminopropionitrile; Animals; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Elasticity; Elastin; Extracellular Matrix; Hydroxyproline; Hypertension, Pulmonary; Hypoxia; Materials Testing; Mice; Models, Anatomic; Mutation; Pressure; Pulmonary Artery; Stress, Mechanical

2016
Interleukin-3 stimulates matrix metalloproteinase 12 production from macrophages promoting thoracic aortic aneurysm/dissection.
    Clinical science (London, England : 1979), 2018, 03-30, Volume: 132, Issue:6

    Topics: Aminopropionitrile; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cells, Cultured; Cytokine Receptor Common beta Subunit; Dilatation, Pathologic; Disease Models, Animal; Elastin; Extracellular Signal-Regulated MAP Kinases; Interleukin-3; JNK Mitogen-Activated Protein Kinases; Macrophages; Matrix Metalloproteinase 12; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; Transcription Factor AP-1; Up-Regulation

2018
Nitrosonifedipine, a Photodegradation Product of Nifedipine, Suppresses Pharmacologically Induced Aortic Aneurysm Formation.
    Pharmacology, 2018, Volume: 102, Issue:5-6

    Topics: Aminopropionitrile; Angiotensin II; Animals; Antigens, Differentiation; Antioxidants; Aortic Aneurysm; Chemokine CCL2; Cyclophilins; Disease Models, Animal; Elastin; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Male; Matrix Metalloproteinase 2; Mice; Nifedipine; Nitroso Compounds; Oxidative Stress; Photolysis; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1

2018
Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2020, Volume: 60, Issue:6

    Topics: Aminopropionitrile; Animals; Antibodies; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Apoptosis; Disease Models, Animal; Elastin; Interleukin-1beta; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats; Rats, Sprague-Dawley; Survival Rate

2020
Biomechanical consequences of compromised elastic fiber integrity and matrix cross-linking on abdominal aortic aneurysmal enlargement.
    Acta biomaterialia, 2021, 10-15, Volume: 134

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Elastic Tissue; Elastin; Mice; Pancreatic Elastase

2021
Progression and Regression of Abdominal Aortic Aneurysms in Mice.
    Current medical science, 2021, Volume: 41, Issue:5

    Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Abdominal; Collagen; Disease Models, Animal; Disease Progression; Elastin; Extracellular Matrix Proteins; Mice; Mice, Inbred C57BL; Pancreatic Elastase; Protein-Lysine 6-Oxidase; Up-Regulation

2021
Intramural injection of pluronic gel loaded with drugs to alleviate arterial injury.
    Microvascular research, 2022, Volume: 142

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Disease Models, Animal; Elastin; Hyperplasia; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neointima; Poloxamer; Rats; Rats, Sprague-Dawley; Sirolimus

2022
Methamphetamine induces thoracic aortic aneurysm/dissection through C/EBPβ.
    Biochimica et biophysica acta. Molecular basis of disease, 2022, 09-01, Volume: 1868, Issue:9

    Topics: Aminopropionitrile; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; CCAAT-Enhancer-Binding Protein-beta; Elastin; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methamphetamine; Rats; Rats, Sprague-Dawley

2022
Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model.
    Cells, 2022, 10-14, Volume: 11, Issue:20

    Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease Models, Animal; Elastin; Humans; Inflammation; Matrix Metalloproteinase 8; Mice; Mice, Knockout; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1

2022