Page last updated: 2024-08-21

aminophylline and proxyphylline

aminophylline has been researched along with proxyphylline in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199021 (55.26)18.7374
1990's12 (31.58)18.2507
2000's5 (13.16)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Katano, Y; Nakagawa, Y; Nakazawa, M; Takeda, K; Tsukada, T1
Apichartpichean, R; Hasegawa, T; Muraoka, I; Nabeshima, T; Nadai, M; Takagi, K1
Brandis, M; Burghard, R; Gordjani, N; Gundert-Remy, U; Leititis, JU; Püschel, CH1
Doelker, E; Gander, B; Gurny, R; Peppas, NA1
Aasen, AJ; Rasmussen, KE; Ruud-Christensen, M; Salvesen, B1
Hartmann, V; Jörres, R; Magnussen, H1
Jörres, R; Litt, M; Magnussen, H; Reuss, G; Stutz, P1
Kalla, M; Reinhardt, D; Richter, O1
Svedmyr, K1
Bjerve, KS; Selvig, K1
Holzmann, S; Kukovetz, WR; Pöch, G1
Mirsching, G1
Mosbech, H; Paulsen, H; Søborg, M1
Aasen, AJ; Ruud-Christensen, M; Selvig, K1
Eggs, B; Follath, F; Wenk, M1
Bogaert, MG1
Madsen, L; Rasmussen, FV; Waldorff, S1
Garcia, I; Segura, J; Tarrus, E1
Allonen, H; Kanto, J; Kulmala, T; Mäntylä, R; Tala, E1
Bracher, P; Brändli, O1
Selvig, K1
Leeuwin, RS; Ottenhof, M; Ufkes, JG; Zeegers, A; Zuidema, J1
Förster, OB; Geisler, LS; Rohner, HG; Thiel, H1
Graham, NB; McNeill, ME4
Badiger, MV; Graham, NB; McNeill, ME1
Khare, AR; Peppas, NA1
Bourret, E; Brossard, C; Duclos, R1
Peppas, NA; Scott, RA1
Lowman, AM; Peppas, NA1
Bourret, E; Brossard, C; Duclos, R; Ratsimbazafy, V1
Blanco, M; Valverde, I1
Coello, J; Iturriaga, H; Maspoch, S; Porcel, M1
Brazel, CS; Wu, L2
Górska, D; Korzycka, L1

Trials

7 trial(s) available for aminophylline and proxyphylline

ArticleYear
Bronchodilator effect of theophylline preparations and aerosol fenoterol in stable asthma.
    Chest, 1986, Volume: 90, Issue:5

    Topics: Airway Resistance; Aminophylline; Asthma; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Dyphylline; Fenoterol; Forced Expiratory Volume; Humans; Theophylline

1986
[Comparison of the bronchodilator and protective effect of methylxanthines].
    Deutsche medizinische Wochenschrift (1946), 1986, Jan-03, Volume: 111, Issue:1

    Topics: Adolescent; Adult; Aminophylline; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Dyphylline; Ethylenediamines; Female; Humans; Male; Middle Aged; Random Allocation; Theophylline; Xanthines

1986
[Pharmacokinetics and pharmacodynamics of proxyphylline in asthmatic children].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1985, Volume: 133, Issue:8

    Topics: Administration, Oral; Adolescent; Aminophylline; Asthma; Bronchial Provocation Tests; Child; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Injections, Intravenous; Kinetics; Lung Volume Measurements; Male; Metabolic Clearance Rate; Theophylline

1985
[Asthma therapy. Clinical trial of 2 proxyphylline/ephedrine combinations with immediate and long-term effect].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1983, Oct-31, Volume: 59, Issue:30

    Topics: Adult; Aminophylline; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Ephedrine; Female; Humans; Male; Middle Aged; Theophylline

1983
Controlled-release theophylline and proxyphylline in asthmatics: a comparative study.
    Pharmatherapeutica, 1984, Volume: 3, Issue:9

    Topics: Adult; Aged; Aminophylline; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Forced Expiratory Volume; Humans; Middle Aged; Random Allocation; Theophylline

1984
Interaction between proxyphylline and salbutamol.
    International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:8

    Topics: Adolescent; Adult; Albuterol; Aminophylline; Animals; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Guinea Pigs; Humans; Male; Middle Aged; Random Allocation; Theophylline

1981
[Pharmacokinetic and clinical effectiveness of rectally administered theophylline].
    Respiration; international review of thoracic diseases, 1982, Volume: 43, Issue:6

    Topics: Adult; Aged; Aminophylline; Blood Pressure; Double-Blind Method; Drug Combinations; Dyphylline; Humans; Lung; Lung Diseases, Obstructive; Middle Aged; Pulse; Theophylline

1982

Other Studies

31 other study(ies) available for aminophylline and proxyphylline

ArticleYear
Effects of aminophylline, proxyphylline and a proxyphylline-Melilotus extract-rutin mixture (theoesberiven) on the heart and the coronary circulation.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:5

    Topics: Adenosine; Aminophylline; Animals; Blood Volume; Cardiac Output; Coronary Circulation; Coumarins; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Oxygen; Oxygen Consumption; Plant Extracts; Rutin; Stimulation, Chemical; Theophylline

1977
Pharmacokinetic characteristics of N7-substituted theophylline derivatives and their interaction with quinolone in rats.
    Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:10

    Topics: Aminophylline; Animals; Blood Proteins; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Drug Interactions; Dyphylline; Enoxacin; Kidney Tubules; Male; Protein Binding; Quinolones; Rats; Rats, Inbred Strains; Theophylline

1991
Acute intoxication with theophylline, proxyphylline and diprophylline in a 3-month-old infant after rectal application: pharmacokinetic data under hemoperfusion.
    Acta paediatrica Scandinavica, 1990, Volume: 79, Issue:1

    Topics: Administration, Rectal; Aminophylline; Drug Combinations; Dyphylline; Hemoperfusion; Humans; Infant; Male; Theophylline

1990
Effect of polymeric network structure on drug release from cross-linked poly(vinyl alcohol) micromatrices.
    Pharmaceutical research, 1989, Volume: 6, Issue:7

    Topics: Aminophylline; Chemistry, Pharmaceutical; Cross-Linking Reagents; Delayed-Action Preparations; Diffusion; Glutaral; Pharmaceutical Preparations; Polyvinyl Alcohol; Sulfuric Acids; Theophylline

1989
High-performance liquid chromatographic determination of (R)-and (S)-proxyphylline in human plasma.
    Journal of chromatography, 1989, Jul-21, Volume: 491, Issue:2

    Topics: Aminophylline; Camphor; Chromatography, High Pressure Liquid; Humans; Solvents; Stereoisomerism; Theophylline

1989
beta 2-Adrenoceptor stimulants and theophylline in asthma therapy.
    European journal of respiratory diseases. Supplement, 1981, Volume: 116

    Topics: Administration, Oral; Adrenergic beta-Agonists; Aerosols; Albuterol; Aminophylline; Asthma; Bronchodilator Agents; Drug Therapy, Combination; Ephedrine; Heart Rate; Humans; Respiration; Theophylline

1981
Inhibition of human lung cyclic nucleotide phosphodiesterases by proxyphylline, theophylline and their metabolites.
    Acta pharmacologica et toxicologica, 1982, Volume: 51, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Aminophylline; Cytosol; Humans; In Vitro Techniques; Kinetics; Lung; Theophylline

1982
Overadditive synergism between theophylline, diprophylline and proxyphylline in tracheal smooth muscle relaxation.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:10

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Airway Resistance; Aminophylline; Animals; Cattle; Drug Synergism; Dyphylline; Guinea Pigs; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Theophylline; Trachea

1983
Optical resolution, absolute configuration, and activity of the enantiomers of proxyphylline.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:10

    Topics: Aminophylline; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Conformation; Optical Rotation; Stereoisomerism; Structure-Activity Relationship; Theophylline

1983
Simultaneous determination of diprophylline, proxyphylline and theophylline in serum by reversed-phase high-performance liquid chromatography.
    Journal of chromatography, 1983, Sep-09, Volume: 276, Issue:2

    Topics: Adult; Aminophylline; Chromatography, High Pressure Liquid; Dyphylline; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Specimen Handling; Theophylline

1983
Non-linear kinetics of theophylline.
    European journal of respiratory diseases, 1984, Volume: 65, Issue:1

    Topics: Aminophylline; Humans; Kinetics; Theophylline

1984
Pharmacokinetics and bronchodilatory effect of proxyphylline and theophylline.
    European journal of respiratory diseases, 1984, Volume: 65, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Airway Obstruction; Aminophylline; Asthma; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Infusions, Parenteral; Kinetics; Male; Theophylline

1984
Human metabolism of 7-substituted theophyllines: N3-demethylation and lack of oxidation of proxyphylline.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:5

    Topics: Aminophylline; Animals; Biotransformation; Dealkylation; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Oxidation-Reduction; Theophylline; Xanthine Oxidase

1981
Pharmacokinetics of proxyphylline in adults after intravenous and oral administration.
    European journal of clinical pharmacology, 1981, Volume: 19, Issue:2

    Topics: Administration, Oral; Adult; Aminophylline; Biological Availability; Female; Humans; Injections, Intravenous; Kinetics; Male; Theophylline

1981
Efficacy of theophylline and its N-7-substituted derivatives in experimentally induced bronchial asthma in the guinea-pig.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 253, Issue:2

    Topics: Aminophylline; Animals; Asthma; Dyphylline; Female; Guinea Pigs; In Vitro Techniques; Theophylline; Xanthines

1981
[Effectiveness of proxyphylline in chronic obstructive pulmonary disease (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Jun-20, Volume: 105, Issue:25

    Topics: Adult; Aged; Aminophylline; Bronchospirometry; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Plethysmography, Whole Body; Theophylline; Time Factors; Tremor

1980
Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels. 2. Dispersion in an initially dry slab.
    Journal of biomaterials science. Polymer edition, 1993, Volume: 5, Issue:1-2

    Topics: Albuterol; Aminophylline; Aspirin; Biocompatible Materials; Diffusion; Dinoprostone; Drug Carriers; Kinetics; Lithium Chloride; Mathematics; Models, Theoretical; Polyethylene Glycols; Solubility; Surface Properties; Theophylline

1993
Porogens in the preparation of microporous hydrogels based on poly(ethylene oxides).
    Biomaterials, 1993, Volume: 14, Issue:14

    Topics: Aminophylline; Biocompatible Materials; Calorimetry, Differential Scanning; Delayed-Action Preparations; Diffusion; Gels; Magnetic Resonance Spectroscopy; Molecular Weight; Polyethylene Glycols; Polyurethanes; Porosity; Spectrophotometry, Ultraviolet; Theophylline; Vitamin B 12

1993
Release behavior of bioactive agents from pH-sensitive hydrogels.
    Journal of biomaterials science. Polymer edition, 1993, Volume: 4, Issue:3

    Topics: Acrylic Resins; Aminophylline; Biocompatible Materials; Diffusion; Drug Carriers; Drug Delivery Systems; Gels; Hydrogen-Ion Concentration; Methacrylates; Osmolar Concentration; Oxprenolol; Polyhydroxyethyl Methacrylate; Polymers; Theophylline

1993
Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels. 1. Polymer composition.
    Journal of biomaterials science. Polymer edition, 1993, Volume: 4, Issue:3

    Topics: Aminophylline; Biocompatible Materials; Caffeine; Diffusion; Drug Carriers; Drug Delivery Systems; Gels; Models, Chemical; Morphine; Polyethylene Glycols; Polyurethanes; Solubility; Theophylline; Water

1993
Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels: 3. Device geometry.
    Journal of biomaterials science. Polymer edition, 1996, Volume: 7, Issue:11

    Topics: Aminophylline; Asthma; Cross-Linking Reagents; Diffusion; Drug Delivery Systems; Gels; Half-Life; Mathematics; Particle Size; Polyethylene Glycols; Solubility; Surface Properties; Theophylline; Urethane; Water

1996
Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels. 4. Extended constant rate release from partly-coated spheres.
    Journal of biomaterials science. Polymer edition, 1996, Volume: 7, Issue:11

    Topics: Aminophylline; Asthma; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Gels; Hydrogen-Ion Concentration; Osmolar Concentration; Particle Size; Polyethylene Glycols; Rubber; Solubility; Surface Properties; Temperature; Theophylline; Water

1996
Rheology of polyol behenates and drug release from matrix monolithic capsules.
    International journal of pharmaceutics, 1999, May-25, Volume: 182, Issue:2

    Topics: Aminophylline; Capsules; Fatty Acids; Particle Size; Polymers; Solubility; Suspensions; Theophylline; Viscosity

1999
Highly crosslinked, PEG-containing copolymers for sustained solute delivery.
    Biomaterials, 1999, Volume: 20, Issue:15

    Topics: Acrylates; Aminophylline; Biocompatible Materials; Drug Carriers; Kinetics; Polyethylene Glycols; Structure-Activity Relationship; Theophylline

1999
Solute transport analysis in pH-responsive, complexing hydrogels of poly(methacrylic acid-g-ethylene glycol).
    Journal of biomaterials science. Polymer edition, 1999, Volume: 10, Issue:9

    Topics: Aminophylline; Biocompatible Materials; Delayed-Action Preparations; Dextrans; Diffusion; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Hydrogels; Hydrogen-Ion Concentration; In Vitro Techniques; Materials Testing; Molecular Weight; Polyethylene Glycols; Polymethacrylic Acids; Solutions; Theophylline; Vitamin B 12

1999
Rheological behavior of drug suspensions in Gelucire mixtures and proxyphylline release from matrix hard gelatin capsules.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 1999, Volume: 48, Issue:3

    Topics: Aminophylline; Capsules; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion; Excipients; Fats; Gelatin; Lipids; Oils; Rheology; Surface Properties; Suspensions; Theophylline; Viscosity

1999
Application of micellar electrokinetic chromatography to the quality control of a pharmaceutical preparation containing three bronchodilators.
    Electrophoresis, 2002, Volume: 23, Issue:4

    Topics: Aminophylline; Bronchodilator Agents; Chromatography, Micellar Electrokinetic Capillary; Drug Combinations; Drug Compounding; Dyphylline; Linear Models; Methods; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Theophylline

2002
Kinetic-spectrophotometric determination of theophylline, dyphylline, and proxyphylline by use of partial least-squares regression.
    Analytical and bioanalytical chemistry, 2002, Volume: 374, Issue:1

    Topics: Aminophylline; Bronchodilator Agents; Chromatography, High Pressure Liquid; Dyphylline; Hydrogen-Ion Concentration; Kinetics; Least-Squares Analysis; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Theophylline

2002
Surface crosslinking for delayed release of proxyphylline from PHEMA hydrogels.
    International journal of pharmaceutics, 2008, Feb-12, Volume: 349, Issue:1-2

    Topics: Aminophylline; Bronchodilator Agents; Chemistry, Pharmaceutical; Cross-Linking Reagents; Delayed-Action Preparations; Hydrogels; Molecular Weight; Polyhydroxyethyl Methacrylate; Solutions; Surface Properties; Theophylline; Water

2008
Modifying the release of proxyphylline from PVA hydrogels using surface crosslinking.
    International journal of pharmaceutics, 2008, Feb-12, Volume: 349, Issue:1-2

    Topics: Absorption; Aminophylline; Cross-Linking Reagents; Delayed-Action Preparations; Excipients; Glutaral; Hydrogels; Kinetics; Microscopy, Confocal; Spectrophotometry, Ultraviolet; Theophylline

2008
Synthesis, pharmacological activity and nitric oxide generation by nitrate derivatives of theophylline.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:5

    Topics: Aminophylline; Animals; Blood Pressure; Dyphylline; Hypertension; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR; Theophylline

2008