Page last updated: 2024-08-21

aminophylline and methotrexate

aminophylline has been researched along with methotrexate in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (9.09)	18.2507
2000's	4 (36.36)	29.6817
2010's	3 (27.27)	24.3611
2020's	3 (27.27)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bernini, JC; Chappell, WB; Fort, DW; Griener, JC; Kamen, BA; Kane, BJ	1
Cociglio, M; Hansel, S; Hillaire-Buys, D; Margueritte, G; Peyriere, H; Poiree, M	1
Jaksic, W; Lewis, I; Pozza, C; Veljkovic, D	1
Crews, KR; Daw, NC; Inaba, H; Khan, RB; Laningham, FH; Pui, CH	1
Kuhn, AK; Rubin, MF	1
Chan, CH; Kao, WY; Liao, PF; Peng, TR	1
Haque, AU; Jabbar, N; Mirza, S; Razi, W; Sadiq, H; Ullah, R	1

Reviews

1 review(s) available for aminophylline and methotrexate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for aminophylline and methotrexate

Article	Year
Aminophylline for methotrexate-induced neurotoxicity. Lancet (London, England), 1995, Mar-04, Volume: 345, Issue:8949 Topics: Adenosine; Adolescent; Aminophylline; Central Nervous System Diseases; Child; Child, Preschool; Female; Humans; Infusions, Parenteral; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma	1995

Other Studies

9 other study(ies) available for aminophylline and methotrexate

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Reversal of neurologic disturbances related to high-dose methotrexate by aminophylline. Medical and pediatric oncology, 2001, Volume: 36, Issue:6 Topics: Aminophylline; Antimetabolites, Antineoplastic; Child; Humans; Male; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency	2001
Methotrexate-induced leukoencephalopathy reversed by aminophylline and high-dose folinic acid. Acta haematologica, 2004, Volume: 111, Issue:4 Topics: Adult; Aminophylline; Brain Diseases; Female; Humans; Leucovorin; Magnetic Resonance Imaging; Methotrexate; Neurotoxicity Syndromes; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome	2004
Clinical and radiological characteristics of methotrexate-induced acute encephalopathy in pediatric patients with cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:1 Topics: Acute Disease; Adolescent; Aminophylline; Antimetabolites, Antineoplastic; Bone Neoplasms; Brain; Child; Diffusion Magnetic Resonance Imaging; Female; Histiocytoma, Malignant Fibrous; Humans; Injections, Intravenous; Injections, Spinal; Leukemia; Male; Metabolic Clearance Rate; Methotrexate; Neurotoxicity Syndromes; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies	2008
Management of methotrexate-induced neurotoxicity with aminophylline plus dextromethorphan in a pediatric patient with pineoblastoma. Pediatric blood & cancer, 2020, Volume: 67, Issue:12 Topics: Adolescent; Aminophylline; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Bronchodilator Agents; Cisplatin; Cyclophosphamide; Dextromethorphan; Disease Management; Drug Therapy, Combination; Etoposide; Excitatory Amino Acid Antagonists; Female; Humans; Methotrexate; Neurotoxicity Syndromes; Pineal Gland; Pinealoma; Prognosis	2020
High-Dose Aminophylline for Methotrexate-Induced Neurotoxicity in a Patient With Brain Metastasis. American journal of therapeutics, 2021, 01-20, Volume: 28, Issue:6 Topics: Aminophylline; Brain; Brain Neoplasms; Humans; Methotrexate; Neurotoxicity Syndromes	2021
Safety and Efficacy of Aminophylline in Intrathecal Methotrexate-related Neurological Toxicity in Large Pediatric Oncology Centre. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2021, Volume: 30, Issue:4 Topics: Aminophylline; Child; Humans; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies	2021