aminopentol has been researched along with sphingosine in 5 studies
| Studies (aminopentol) | Trials (aminopentol) | Recent Studies (post-2010) (aminopentol) | Studies (sphingosine) | Trials (sphingosine) | Recent Studies (post-2010) (sphingosine) |
|---|---|---|---|---|---|
| 14 | 0 | 3 | 8,325 | 117 | 3,459 |
| Protein | Taxonomy | aminopentol (IC50) | sphingosine (IC50) |
|---|---|---|---|
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | 6.3125 | |
| cAMP-dependent protein kinase catalytic subunit alpha | Rattus norvegicus (Norway rat) | 0.098 | |
| Sphingosine kinase 2 | Homo sapiens (human) | 1.56 | |
| Sphingosine kinase 1 | Homo sapiens (human) | 3.86 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dombrink-Kurtzman, MA; Kawasaki, T; Kozutsumi, Y; Merrill, AH; Roberts, PC; Schmelz, EM | 1 |
| Humpf, HU; Liotta, DC; Menaldino, DS; Meredith, FI; Merrill, AH; Schmelz, EM; Vales, TR; Vesper, H; Wang, E | 1 |
| Abel, S; Gelderblom, WC; Shephard, GS; Snyman, SD; Swanevelder, S; van der Westhuizen, L | 1 |
| Meredith, FI; Merrill, AH; Riley, RT; Wang, E | 1 |
| Allegood, J; Desai, K; Hartl, M; Humpf, HU; Liotta, DC; Merrill, AH; Peng, Q; Schmelz, EM; Sullards, MC; Wang, E | 1 |
1 review(s) available for aminopentol and sphingosine
| Article | Year |
|---|---|
Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis.
Topics: Animals; Apoptosis; Carboxylic Acids; Carcinogens; Carcinoma, Hepatocellular; Cells, Cultured; Enzyme Inhibitors; Fumonisins; Glycosphingolipids; Humans; Liver Neoplasms; Oxidoreductases; Sphingolipids; Sphingosine; Zea mays | 2002 |
4 other study(ies) available for aminopentol and sphingosine
| Article | Year |
|---|---|
Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases.
Topics: Antifungal Agents; Apoptosis; Carboxylic Acids; Carcinogens, Environmental; Cell Count; Cell Survival; DNA Fragmentation; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Food Contamination; Fumonisins; HT29 Cells; Humans; Mycotoxins; Sphingolipids; Sphingosine; Zea mays | 1998 |
Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor.
Topics: Acylation; Carboxylic Acids; Fumonisins; Humans; Hydrolysis; Kinetics; Mycotoxins; Oxidoreductases; Palmitic Acid; Pancreatitis-Associated Proteins; Sphingosine | 1998 |
Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds.
Topics: Alternaria; Animals; Carboxylic Acids; Carcinogens, Environmental; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fumonisins; L-Lactate Dehydrogenase; Liver; Male; Mycotoxins; Oxidoreductases; Protein Kinase C; Rats; Rats, Inbred F344; Sphingolipids; Sphingosine; Structure-Activity Relationship | 1998 |
Fumonisin B1 consumption by rats causes reversible, dose-dependent increases in urinary sphinganine and sphingosine.
Topics: Animals; Carboxylic Acids; Diet; Dose-Response Relationship, Drug; Fumonisins; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Sphingosine; Time Factors | 1999 |