aminopenicillanic acid has been researched along with glycine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Fong, GW; Johnson, RN; Kho, BT; Martin, DT | 1 |
| Galunsky, B; Kasche, V | 1 |
| Svedas, VK; Youshko, MI | 1 |
| Alonso, J; Fernández-Lafuente, R; Fernández-Lorente, G; García-López, JL; Guisan, JM; Hernández-Jústiz, O; Mateo, C; Moreno, MA; Terreni, M | 1 |
| Diender, MB; Heijnen, JJ; Ras, C; Straathof, AJ; van der Does, T | 1 |
| de Vroom, E; Sheldon, RA; Svedas, VK; van Langen, LM; van Rantwijk, F; Youshko, MI | 1 |
| Fernandez-Lafuente, R; Giordano, RC; Giordano, RL; Gonçalves, LR; Guisan, JM; Sousa, R | 1 |
| Fernandez-Lafuente, R; Giordano, RC; Giordano, RL; Gonçalves, LR; Guisan, JM | 1 |
| Alkema, WB; de Vries, E; Floris, R; Janssen, DB | 1 |
| Gabor, EM; Janssen, DB | 1 |
| Liu, RJ; Xu, XM; Zhang, YW | 1 |
12 other study(ies) available for aminopenicillanic acid and glycine
| Article | Year |
|---|---|
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Determination of degradation products and impurities of amoxicillin capsules using ternary gradient elution high-performance liquid chromatography.
Topics: Amoxicillin; Capsules; Chromatography, High Pressure Liquid; Glycine; Penicillanic Acid; Spectrophotometry, Ultraviolet | 1984 |
Ionic strength and pH effects in the kinetically controlled synthesis of benzylpenicillin by nucleophilic deacylation of free and immobilized phenyl-acetyl-penicillin amidase with 6-aminopenicillanic acid.
Topics: Amidohydrolases; Enzymes, Immobilized; Glycine; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Penicillanic Acid; Penicillin Amidase; Penicillin G; Phenylacetates | 1982 |
Kinetics of ampicillin synthesis catalyzed by penicillin acylase from E. coli in homogeneous and heterogeneous systems. Quantitative characterization of nucleophile reactivity and mathematical modeling of the process.
Topics: Ampicillin; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Models, Theoretical; Penicillanic Acid; Penicillin Amidase; Temperature | 2000 |
Biotransformations catalyzed by multimeric enzymes: stabilization of tetrameric ampicillin acylase permits the optimization of ampicillin synthesis under dissociation conditions.
Topics: Acetobacter; Ampicillin; Bioreactors; Catalysis; Enzyme Stability; Enzymes, Immobilized; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Methanol; Molecular Structure; Penicillanic Acid; Penicillin Amidase; Phosphates; Protein Structure, Quaternary; Temperature | 2001 |
Equilibrium modeling of extractive enzymatic hydrolysis of penicillin G with concomitant 6-aminopenicillanic acid crystallization.
Topics: Acetates; Catalysis; Chromatography, High Pressure Liquid; Computer Simulation; Crystallization; Escherichia coli; Fermentation; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Models, Chemical; Penicillanic Acid; Penicillin Amidase; Penicillin G; Potassium; Reproducibility of Results; Sensitivity and Specificity; Water | 2002 |
Penicillin acylase-catalyzed ampicillin synthesis using a pH gradient: a new approach to optimization.
Topics: Ampicillin; Catalysis; Cell Line; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Models, Chemical; Penicillanic Acid; Penicillin Amidase; Protons; Quality Control; Sensitivity and Specificity | 2002 |
Enzymatic synthesis of amoxicillin: avoiding limitations of the mechanistic approach for reaction kinetics.
Topics: Amoxicillin; Bioreactors; Computer Simulation; Enzymes, Immobilized; Gels; Glycine; Kinetics; Models, Chemical; Neural Networks, Computer; Penicillanic Acid; Penicillin Amidase; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Sepharose | 2002 |
Inhibitory effects in the side reactions occurring during the enzymic synthesis of amoxicillin: p-hydroxyphenylglycine methyl ester and amoxicillin hydrolysis.
Topics: Amoxicillin; Enzyme Inhibitors; Enzymes, Immobilized; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Methanol; Models, Theoretical; Penicillanic Acid; Penicillin Amidase | 2003 |
Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics.
Topics: Acylation; Anti-Bacterial Agents; Binding Sites; Binding, Competitive; Catalysis; Cephalosporins; Deuterium; Escherichia coli; Glycine; Hydrolysis; Kinetics; Penicillanic Acid; Penicillin Amidase; Phenylacetates; Protons; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
Increasing the synthetic performance of penicillin acylase PAS2 by structure-inspired semi-random mutagenesis.
Topics: beta-Lactams; Catalysis; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Escherichia coli; Genetic Techniques; Glycine; Hydrolysis; Kinetics; Models, Chemical; Mutagenesis; Mutation; Penicillanic Acid; Penicillin Amidase; Plasmids; Protein Conformation; Protein Engineering; Time Factors | 2004 |
One-pot, two-step enzymatic synthesis of amoxicillin by complexing with Zn2+.
Topics: Amoxicillin; Biotechnology; Glycine; Kluyvera; Penicillanic Acid; Penicillin Amidase; Penicillin G; Technology, Pharmaceutical; Zinc | 2010 |