aminoimidazole carboxamide has been researched along with thiophenes in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 24 (77.42) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Eglen, RM; Flippin, LA; Kim, EJ; Lazar, DA; Leung, E; Seran, CS; Walsh, LK; Wong, EH | 1 |
| Richardt, G; Schreieck, J | 1 |
| Guigas, B; Hue, L; Musi, N; Reyna, SM; Sakamoto, K; Taleux, N; Viollet, B | 1 |
| Barres, R; Glund, S; Long, YC; Treebak, JT; Viollet, B; Wojtaszewski, JF; Zierath, JR | 1 |
| Alzamora, R; Gong, F; Hallows, KR; Li, H; Neumann, D; Pastor-Soler, NM; Smolak, C | 1 |
| Akifusa, S; Fujimoto, A; Hirofuji, T; Kamio, N; Nonaka, K; Yamashita, Y | 1 |
| Carpentier, S; Courtoy, PJ; Gueuning, MA; Horman, S; Hue, L; Hussain, N; Miranda, L; Ozkan, Y; Platek, A; Rider, MH; Sid, B; Vertommen, D | 1 |
| Baudot, R; Cren-Olivé, C; Feidt, C; Fratta, C; Lazartigues, A; Thomas, M; Wiest, L | 1 |
| Fleming, RM; Hrafnsdóttir, S; Magnúsdóttir, M; Paglia, G; Palsson, BØ; Thiele, I; Thorlacius, S | 1 |
| Beullens, M; Bultot, L; Foretz, M; Guigas, B; Guinovart, JJ; Hue, L; Hussain, N; Maisin, L; Rider, MH; Sakamoto, K; Vertommen, D; Viollet, B; Von Wilamowitz-Moellendorff, A | 1 |
| Austin, RL; Benziane, B; Björnholm, M; Chibalin, AV; Kotova, O; Pirkmajer, S; Viollet, B; Zierath, JR | 1 |
| Durante, W; Liu, XM; Peyton, KJ; Yates, B; Yu, Y | 1 |
| Barroso, E; Coll, T; Gómez-Foix, AM; Palomer, X; Salmerón, E; Salvadó, L; Vázquez-Carrera, M | 1 |
| Bertrand, L; Bultot, L; Deak, M; Ducommun, S; Ford, RJ; Kemp, BE; Sakamoto, K; Steinberg, GR | 1 |
| Carroll, JL; Kang, D; Kim, D; Kim, I; Martin, EA | 1 |
| Foretz, M; Hallén, S; Kviklyte, S; Lai, YC; Lantier, L; Rider, MH; Vertommen, D; Viollet, B | 1 |
| Altman, MD; Bachman, E; Bouthillette, M; Chan, G; Childers, KK; Haidle, AM; Marshall, CG; Mathur, A; Mo, JR; Rosenstein, C; Rush, T; Tempest, P; Xu, L; Young, JR; Zabierek, AA | 1 |
| Calderon, PB; Dejeans, N; Glorieux, C; Najimi, M; Renard, P; Rommelaere, G; Sid, B; Valenzuela, M; Verrax, J | 1 |
| Blagih, J; Coelho, PP; Griss, T; Jones, RG; Vincent, EE; Viollet, B | 1 |
| Chung, FF; Hii, LW; Ho, GF; Leong, CO; Malik, RA; Ng, CH; See, MH; Soo, JS; Taib, NA; Tan, BS; Tan, SH; Teh, YC; Teo, SH; Yip, CH | 1 |
| Abate, M; Levine, JS; Lieberthal, W; Lusco, M; Tang, M | 1 |
| Ma, A; Wang, J; Zhao, M; Zhu, H | 1 |
| Bizjak, M; Dolinar, K; Malavašič, P; Pavlin, M; Pirkmajer, S; Pohar, J | 1 |
| Boudaba, N; Foretz, M; Huet, C; Marion, A; Pierre, R; Viollet, B | 1 |
| Dohmen, M; Krieg, S; Lüscher, B; Vervoorts, J | 1 |
| Berggreen, C; Degerman, E; Ekelund, M; Göransson, O; Holm, C; Kopietz, F; Larsson, S; Sakamoto, K; Säll, J | 1 |
| Miyamoto, L | 1 |
| Dai, J; Peng, XW; Zhang, L; Zhou, HH | 1 |
| Chen, H; Leung, SWS; Vanhoutte, PM | 1 |
| Jiang, Y; Jin, R; Li, J; Li, Y; Shi, L; Yang, L; Zhong, D | 1 |
| Alghamdi, F; Alshuweishi, Y; Bijland, S; Degerman, E; Göransson, O; Kopietz, F; Sakamoto, K; Salt, IP | 1 |
4 review(s) available for aminoimidazole carboxamide and thiophenes
| Article | Year |
|---|---|
Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biphenyl Compounds; Enzyme Activators; Glucose; Homeostasis; Humans; Molecular Structure; Phosphorylation; Pyrones; Ribonucleosides; Thiophenes | 2009 |
[AMPK as a Metabolic Intersection between Diet and Physical Exercise].
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biphenyl Compounds; Diet; Drug Discovery; Eating; Exercise; Exercise Therapy; Humans; Hypoglycemic Agents; Isoenzymes; Metabolic Diseases; Metformin; Molecular Targeted Therapy; Muscle Contraction; Pyrones; Ribonucleosides; Thiophenes | 2018 |
[Advances on the anti-inflammatory and protective effect of AMPK activators].
Topics: Adiponectin; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Enzyme Activation; Inflammation; Metformin; Pyrones; Thiophenes | 2019 |
AMPK: Potential Therapeutic Target for Alzheimer's Disease.
Topics: Alzheimer Disease; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Autophagy; Biphenyl Compounds; Clinical Trials as Topic; Gene Expression Regulation; Humans; Insulin Resistance; Mitochondria; Neuroprotective Agents; Oxidative Stress; Phosphorylation; Pyrones; Ribonucleotides; tau Proteins; Thiophenes | 2020 |
27 other study(ies) available for aminoimidazole carboxamide and thiophenes
| Article | Year |
|---|---|
Enhancement of adenosine A1 receptor functions by benzoylthiophenes in guinea pig tissues in vitro.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Electric Stimulation; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Male; Muscle Contraction; Myocardial Contraction; Peptides; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Receptors, Purinergic P1; Ribonucleosides; Thienopyridines; Thiophenes; Wasp Venoms | 1995 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Enzyme Activation; Hypoglycemic Agents; Interleukin-6; Ionomycin; Ionophores; Mice; Mice, Transgenic; Muscle, Skeletal; Organ Culture Techniques; Protein Subunits; Pyrones; Ribonucleotides; Thiophenes | 2009 |
AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Bucladesine; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Epididymis; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Macaca mulatta; Male; Mice; Phosphorylation; Protein Transport; Pyrones; Rats; Rats, Sprague-Dawley; Ribonucleotides; RNA Interference; RNA, Small Interfering; Thiophenes; Transfection; Vacuolar Proton-Translocating ATPases | 2009 |
Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.
Topics: Adiponectin; Aminoimidazole Carboxamide; Androstadienes; Animals; Biphenyl Compounds; Cells, Cultured; Deoxyglucose; Intracellular Signaling Peptides and Proteins; Macrophages; Mice; Nitric Oxide; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Pyrones; Reactive Oxygen Species; Ribonucleotides; Sirolimus; Structure-Activity Relationship; Thiophenes; TOR Serine-Threonine Kinases; Wortmannin | 2010 |
AMP-activated protein kinase induces actin cytoskeleton reorganization in epithelial cells.
Topics: Actin Depolymerizing Factors; Actins; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cell Line; Cytoskeleton; Dogs; Epithelial Cells; Naphthalimides; Osmotic Pressure; Paxillin; Phosphorylation; Pyrones; rho-Associated Kinases; Ribonucleotides; Saline Solution, Hypertonic; Thiophenes | 2010 |
Multiresidue method for the determination of 13 pesticides in three environmental matrices: water, sediments and fish muscle.
Topics: Acetamides; Aminoimidazole Carboxamide; Animals; Benzimidazoles; Carbamates; Chemical Fractionation; Chromatography, Liquid; Environmental Monitoring; Fishes; Geologic Sediments; Hydantoins; Isoxazoles; Methacrylates; Muscles; Naphthalenes; Niacinamide; Oxazolidinones; Pesticide Residues; Pesticides; Phenylurea Compounds; Propionates; Pyrimidines; Quinoxalines; Reproducibility of Results; Solid Phase Extraction; Strobilurins; Sulfonylurea Compounds; Tandem Mass Spectrometry; Thiophenes; Water Pollutants, Chemical | 2011 |
Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS).
Topics: Aminoimidazole Carboxamide; Biphenyl Compounds; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Mass Spectrometry; Metabolomics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines; Pyrimidines; Pyrones; Reproducibility of Results; Ribonucleotides; Thiophenes | 2012 |
AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase.
Topics: Amino Acid Sequence; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apraxia, Ideomotor; Biphenyl Compounds; Cells, Cultured; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Activators; Glycogen Synthase; Hepatocytes; Humans; Liver; Male; Mice; Mice, Knockout; Phosphorylation; Protein Processing, Post-Translational; Pyrones; Rats; Rats, Wistar; Ribonucleotides; Thiophenes | 2012 |
Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Blotting, Western; Carboxylic Ester Hydrolases; Cell Hypoxia; Cells, Cultured; Enzyme Activation; Methylation; Mice; Mice, Knockout; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphorylation; Protein Kinase C; Protein Subunits; Pyrones; Rats; Ribonucleotides; RNA Interference; Sodium-Potassium-Exchanging ATPase; Thiophenes | 2012 |
Activation of AMP-activated protein kinase inhibits the proliferation of human endothelial cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biphenyl Compounds; Cell Cycle Proteins; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclin A; Enzyme Activation; G1 Phase; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide Synthase Type III; Phosphorylation; Pyrones; Resting Phase, Cell Cycle; Retinoblastoma Protein; Ribonucleotides; Thiophenes | 2012 |
Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biphenyl Compounds; Cell Line; Cell Nucleus; Chromatography, High Pressure Liquid; Endoplasmic Reticulum; Humans; Inflammation; Insulin Resistance; Lipids; Mice; Muscle Cells; Muscle, Skeletal; NF-kappa B; Oleic Acid; Palmitic Acid; Pyrones; Ribonucleotides; Signal Transduction; Thiophenes | 2013 |
Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662.
Topics: Allosteric Regulation; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Cell Line; Cells, Cultured; Enzyme Activators; Glucose; Hepatocytes; Hypoglycemic Agents; Lipogenesis; Mice; Mice, Inbred C57BL; Mice, Knockout; Myoblasts; Phosphorylation; Protein Processing, Post-Translational; Protein Subunits; Pyrones; Recombinant Proteins; Ribonucleotides; Signal Transduction; Thiophenes | 2014 |
Effects of modulators of AMP-activated protein kinase on TASK-1/3 and intracellular Ca(2+) concentration in rat carotid body glomus cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Calcium; Carotid Body; Enzyme Activators; Enzyme Inhibitors; Hypoxia; Intracellular Space; Membrane Potentials; Nerve Tissue Proteins; Patch-Clamp Techniques; PC12 Cells; Phosphorylation; Potassium Channels, Tandem Pore Domain; Pyrones; Rats; Rats, Sprague-Dawley; Ribonucleotides; Thiophenes | 2014 |
A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators.
Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Biphenyl Compounds; Enzyme Activation; Fatty Acids; Glucose; Glycogen; Male; Mice; Muscle Contraction; Muscle, Skeletal; Pyrones; Rats; Ribonucleotides; Thiophenes | 2014 |
Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms.
Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Disease Models, Animal; Enzyme Activation; Humans; Janus Kinase 2; Leukemia, Myeloid, Acute; Microsomes; Models, Biological; Molecular Structure; Protein Kinase Inhibitors; Rats; Thiophenes | 2014 |
AICAR induces Nrf2 activation by an AMPK-independent mechanism in hepatocarcinoma cells.
Topics: Active Transport, Cell Nucleus; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biphenyl Compounds; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Liver Neoplasms; NF-E2-Related Factor 2; Phosphorylation; Pyrones; Ribonucleosides; Thiophenes | 2014 |
Differential effects of AMPK agonists on cell growth and metabolism.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biphenyl Compounds; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Glucose; HCT116 Cells; HEK293 Cells; Humans; Hypoglycemic Agents; Lactic Acid; Metformin; Mice; Neoplasms; Phenformin; Pyrones; Ribonucleotides; Sodium Salicylate; Thiophenes | 2015 |
Metformin synergizes 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) combination therapy through impairing intracellular ATP production and DNA repair in breast cancer stem cells.
Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cyclophosphamide; DNA Damage; DNA Repair; Drug Combinations; Drug Synergism; Embryonic Stem Cells; Epirubicin; Female; Fibroblasts; Fluorouracil; Glucose; Humans; Hypoglycemic Agents; Lactic Acid; Lung; Metformin; Neoplastic Stem Cells; Pyrones; Ribonucleotides; Thiophenes | 2015 |
Preconditioning mice with activators of AMPK ameliorates ischemic acute kidney injury in vivo.
Topics: Acute Kidney Injury; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Biphenyl Compounds; Ischemia; Ischemic Preconditioning; Kidney; Mice; Protective Agents; Pyrones; Ribonucleotides; Thiophenes | 2016 |
AMPK activation reduces the number of atheromata macrophages in ApoE deficient mice.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Antigens, Ly; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Biphenyl Compounds; Cell Line; Cell Migration Inhibition; Chemotaxis; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Genetic Predisposition to Disease; Humans; Macrophages; Metformin; Mice, Knockout; Phenotype; Pyrones; Receptors, CCR2; Ribonucleotides; Signal Transduction; Thiophenes | 2017 |
Combined treatment with Metformin and 2-deoxy glucose induces detachment of viable MDA-MB-231 breast cancer cells in vitro.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biphenyl Compounds; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Enzyme Activation; Female; Humans; Metformin; Pyrones; Ribonucleotides; Thiophenes | 2017 |
AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Cells, Cultured; Down-Regulation; Enzyme Activation; Fatty Acids; Fatty Liver; Gene Expression Regulation; Hepatocytes; Humans; Lipogenesis; Liver; Male; Metformin; Mice, Knockout; Oxidation-Reduction; Protein Serine-Threonine Kinases; Pyrones; Ribonucleotides; Small Molecule Libraries; Thiophenes | 2018 |
Studying the Role of AMPK in Autophagy.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Autophagy; Biomarkers; Biphenyl Compounds; Cell Line, Tumor; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Fibroblasts; Fluorescent Antibody Technique; Humans; Immunoblotting; Macrolides; Mice; NIH 3T3 Cells; Pyrones; Ribonucleotides; Thiophenes | 2018 |
AMPK activation by A-769662 and 991 does not affect catecholamine-induced lipolysis in human adipocytes.
Topics: Adenylate Kinase; Adipocytes; Adipose Tissue; Aminoimidazole Carboxamide; Animals; Biphenyl Compounds; Catecholamines; Female; Humans; Lipolysis; Male; Mice; Phosphorylation; Pyrones; Rats; Rats, Sprague-Dawley; Ribonucleotides; Sterol Esterase; Thiophenes | 2018 |
Acute activation of endothelial AMPK surprisingly inhibits endothelium-dependent hyperpolarization-like relaxations in rat mesenteric arteries.
Topics: Acetylcholine; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Bradykinin; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Mice, Inbred C57BL; Pyrones; Rats, Sprague-Dawley; Ribonucleotides; Swine; Thiophenes; Vasodilation | 2019 |
A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner.
Topics: 3T3-L1 Cells; Adenylate Kinase; Adipocytes; Allosteric Site; Amino Acid Substitution; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cells, Cultured; Enzyme Activation; Female; Gene Knock-In Techniques; Glucose; Humans; Insulin; Male; Mice; Mice, Inbred C57BL; Mutation, Missense; Phosphorylation; Protein Processing, Post-Translational; Pyrones; Rats; Rats, Sprague-Dawley; Ribonucleotides; Thiophenes | 2021 |