aminoimidazole carboxamide has been researched along with purine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (58.62) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 5 (17.24) | 29.6817 |
| 2010's | 4 (13.79) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Holmes, EW; Meade, JC; Thomas, CB | 1 |
| Downs, SM | 1 |
| Cascante, M; Curto, R; Voit, EO | 1 |
| Allen, S; Downs, DM; Zilles, JL | 1 |
| BUCHANAN, JM; SCHULMAN, MP | 1 |
| CONZELMAN, GM; MANDEL, HG; SMITH, PK | 1 |
| BUCHANAN, JM; WILLIAMS, WJ | 1 |
| BUCHANAN, JM; KORN, ED | 1 |
| NOGUCHI, T | 1 |
| MANDEL, HG; SMITH, PK; WAY, JL | 1 |
| BUCHANAN, JM; ERWIN, MJ; FLAKS, JG | 2 |
| BEAU-THOME, F; HEDEGAARD, J; ROCHE, J | 2 |
| LAJTHA, LG; NOYES, WD; OLIVER, R | 1 |
| CITTADINI, D; HEDEGAARD, J; LEGAL, ML; LEGAL, Y; ROCHE, J | 1 |
| KURAMITSU, HK; MOYED, HS; UDAKA, S | 1 |
| GOTS, JS | 1 |
| BEN-ISHAI, R; BERGMANN, ED; VOLCANI, B | 1 |
| BEN-ISHAI, R; BERGMANN, ED; VOLCANI, BE | 1 |
| Alarcón, GS; Baggott, JE; Lee, JY; Morgan, SL; Oster, RA | 1 |
| Ownby, K; White, RH; Xu, H | 1 |
| Beckers, A; Brusselmans, K; Deboel, L; Derua, R; Organe, S; Swinnen, JV; Timmermans, L; Vanderhoydonc, F; Verhoeven, G; Waelkens, E | 1 |
| Coulpier, F; Daignan-Fornier, B; Lemoine, S; Pinson, B; Sagot, I; Vaur, S | 1 |
| Boutchueng-Djidjou, M; Collard-Simard, G; Faure, RL; Fortier, S; Hébert, SS; Kelly, I; Landry, CR | 1 |
| Becerra, A; Lazcano, A; Vázquez-Salazar, A | 1 |
| Chen, X; Gotoh, N; Horike, SI; Igarashi, K; Kato, K; Kita, K; Kohno, S; Meguro-Horike, M; Mukaida, N; Murayama, T; Nakata, A; Nishi, K; Nishimura, T; Saitoh, K; Sasaki, S; Soga, T; Takahashi, C; Tojo, A; Yano, S | 1 |
| Asakawa, T; Choi, JH; Hirai, H; Ikeuchi, K; Inai, M; Kan, T; Kawagishi, H; Matsuzaki, N; Motohashi, R; Takemura, H; Taniguchi, Y; Wu, J | 1 |
| Boeckx, C; Burkhalter, MD; Dutto, I; Gerhards, J; Herrera, A; Junza, A; Lüders, J; Philipp, M; Pons, S; Škopová, V; Smak, JA; Souckova, O; Stracker, TH; Yanes, O; Zikánová, M | 1 |
1 trial(s) available for aminoimidazole carboxamide and purine
| Article | Year |
|---|---|
The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis.
Topics: Adenosine; Aminoimidazole Carboxamide; Arthritis, Rheumatoid; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Purines; Pyridoxine; Ribonucleotides; Treatment Outcome; Vitamin B 12 | 2004 |
28 other study(ies) available for aminoimidazole carboxamide and purine
| Article | Year |
|---|---|
Aminoimidazole carboxamide ribonucleoside toxicity: a model for study of pyrimidine starvation.
Topics: Aminoimidazole Carboxamide; Animals; Cell Division; Cell Line; Cricetinae; Cricetulus; Fibroblasts; Imidazoles; Lung; Models, Biological; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Ribonucleosides | 1981 |
Involvement of purine nucleotide synthetic pathways in gonadotropin-induced meiotic maturation in mouse cumulus cell-enclosed oocytes.
Topics: Aminoimidazole Carboxamide; Animals; Azaserine; Chromatography, High Pressure Liquid; Cyclic AMP; Follicle Stimulating Hormone; Hypoxanthine; Meiosis; Mice; Mice, Inbred C57BL; Oocytes; Oogenesis; Purines; Ribonucleosides; Signal Transduction | 1997 |
Analysis of abnormalities in purine metabolism leading to gout and to neurological dysfunctions in man.
Topics: Adenylosuccinate Lyase; Aminoimidazole Carboxamide; AMP Deaminase; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Models, Biological; Models, Chemical; Purines; Ribonucleotides; Ribose-Phosphate Pyrophosphokinase; Uric Acid | 1998 |
Metabolic flux in both the purine mononucleotide and histidine biosynthetic pathways can influence synthesis of the hydroxymethyl pyrimidine moiety of thiamine in Salmonella enterica.
Topics: Aminoimidazole Carboxamide; Bacterial Proteins; Gene Expression Regulation, Bacterial; Histidine; Point Mutation; Purines; Pyrimidines; Ribonucleotides; Salmonella enterica; Suppression, Genetic; Thiamine; Thiamine Pyrophosphate | 2002 |
Biosynthesis of the purines. II. Metabolism of 4-amino-5-imidazolecarboxamide in pigeon liver.
Topics: Aminoimidazole Carboxamide; Animals; Columbidae; Liver; Purines; Xanthines | 1952 |
The incorporation of radiocarbon from 4-amino-5-imidazolecarboxamide into the purines of tumor-bearing mice.
Topics: Aminoimidazole Carboxamide; Animals; Imidazoles; Mice; Neoplasms; Purines | 1953 |
Biosynthesis of the purines. IV. The metabolism of 4-amino-5-imidazolecarboxamide in yeast.
Topics: Aminoimidazole Carboxamide; Imidazoles; Purines; Yeasts | 1953 |
Biosynthesis of the purines. VI. Purification of liver nucleoside phosphorylase and demonstration of nucleoside synthesis from 4-amino-5-imidazolecarboxamide, adenine, and 2, 6-diaminopurine.
Topics: Adenine; Aminoimidazole Carboxamide; DNA; Liver; Pentosyltransferases; Purines; RNA | 1955 |
Studies on the biosynthesis of nucleic acids. I. On the rôle of 4-aminoimidazole-5-carboxamide as a precursor of polynucleotide purines.
Topics: Aminoimidazole Carboxamide; Imidazoles; Nucleic Acids; Nucleotides; Polynucleotides; Purines | 1956 |
The effect of 4-amino-5-imidazolecarboxamide on the incorporation of purines into liver nucleic acids of the mouse.
Topics: Aminoimidazole Carboxamide; Animals; Imidazoles; Liver; Mice; Nucleic Acids; Purines | 1957 |
Biosynthesis of the purines. XVI. The synthesis of adenosine 5'-phosphate and 5-amino-4-imidazolecarboxamide ribotide by a nucleotide pyrophosphorylase.
Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; Nucleosides; Nucleotides; Phosphorylases; Purines; Pyrophosphatases | 1957 |
Biosynthesis of the purines. XVIII. 5-Amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase and inosinicase.
Topics: Aminoimidazole Carboxamide; Enzymes; Hydroxymethyl and Formyl Transferases; Liver; Nucleotide Deaminases; Phosphates; Purines; Transferases | 1957 |
[Effect of histidine and its metabolites on biosynthesis of purines by Escherichia coli B. II. Effect of histidine on formation of 5(4)-amino-4(5)-imidazolecarboxamide in presence of sulfadiazine].
Topics: Aminoimidazole Carboxamide; Escherichia coli; Histidine; Metabolic Networks and Pathways; Purines; Sulfadiazine | 1958 |
[Influence of histidine and its metabolites on the biosynthesis of purines by Escherichia coli B. III. Mode of action of histidine in biosynthesis of 5(4)-amino-4(5)-imidazolecarboxamide].
Topics: Aminoimidazole Carboxamide; Escherichia coli; Histidine; Imidazoles; Purines | 1958 |
On the utilization of 5-amino-4-imidazole carboxamide (AICA) for purine synthesis by bone marrow cells in vitro.
Topics: Aminoimidazole Carboxamide; Bone Marrow; Bone Marrow Cells; Imidazoles; In Vitro Techniques; Purines | 1959 |
[INFLUENCE OF HISTIDINE AND ITS METABOLITES ON THE BIOSYNTHESIS OF PURINES IN ESCHERICHIA COLI B. VI. INCORPORATION OF THE IMIDE NITROGEN OF FORMIMINOGLUTAMIC AND -ASPARTIC ACIDS INTO 5-AMINO-4-IMIDAZOLECARBOXAMIDE RIBOTIDE].
Topics: Aminoimidazole Carboxamide; Aspartic Acid; Escherichia coli; Glutamates; Histidine; Imidazoles; Imides; Metabolism; Nitrogen; Pharmacology; Purines; Research; Ribonucleotides | 1963 |
INDUCTION OF INOSINE 5'-PHOSPHATE DEHYDROGENASE AND XANTHOSINE 5'-PHOSPHATE AMINASE BY RIBOSYL-4-AMINO-5-IMIDAZOLECARBOXAMIDE IN PURINE-REQUIRING MUTANTS OF ESCHERICHIA COLI B.
Topics: Adenine Nucleotides; Aminoimidazole Carboxamide; Carbon Isotopes; Chromatography; Escherichia coli; Guanine Nucleotides; Imidazoles; Inosine; Kinetics; Ligases; Metabolism; Oxidoreductases; Phosphates; Purines; Research; Ribonucleosides; Xanthines | 1964 |
The accumulation of 4-amino-5-imidazolecarboxamide by a purine-requiring mutant of Escherichia coli.
Topics: Aminoimidazole Carboxamide; Escherichia coli; Imidazoles; Purines | 1950 |
4-Amino-imidazole-5-carboxamide, precursor of the purines in E. coli.
Topics: Aminoimidazole Carboxamide; Escherichia coli; Imidazoles; Purines | 1951 |
Role of 4-aminoimidazole-5-carboxamide in purine synthesis by Escherichia coli.
Topics: Aminoimidazole Carboxamide; Escherichia coli; Imidazoles; Metabolic Networks and Pathways; Purines; Vitamin A; Vitamins | 1952 |
A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase. A new enzyme in purine biosynthesis.
Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; Enzyme Stability; Genes, Archaeal; Hydrogen-Ion Concentration; Methanococcaceae; Purines; Ribonucleotides; Temperature | 2005 |
Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.
Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA, Neoplasm; Drug Synergism; Enzyme Activation; Humans; Lipids; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase; Protein Serine-Threonine Kinases; Purines; Ribonucleosides; Ribonucleotides; RNA Interference | 2006 |
Metabolic intermediates selectively stimulate transcription factor interaction and modulate phosphate and purine pathways.
Topics: Aminoimidazole Carboxamide; Cell Nucleus; DNA-Binding Proteins; Gene Expression Regulation; Homeodomain Proteins; Homeostasis; Phosphates; Promoter Regions, Genetic; Protein Binding; Protein Transport; Purines; Regulon; Ribonucleotides; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators; Transcription Factors; Up-Regulation | 2009 |
The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biosynthetic Pathways; Cell Membrane; Computational Biology; Endocytosis; Endosomes; Female; Gene Knockdown Techniques; Golgi Apparatus; HEK293 Cells; Humans; Hydro-Lyases; Insulin; Intracellular Signaling Peptides and Proteins; Kinetics; Liver; Mass Spectrometry; Nucleotide Deaminases; Phosphorylation; Proteomics; Purines; Rats, Sprague-Dawley; Receptor, Insulin; Ribonucleotides; Signal Transduction; Sus scrofa | 2015 |
Evolutionary convergence in the biosyntheses of the imidazole moieties of histidine and purines.
Topics: Adenine; Adenosine Triphosphate; Amino Acid Motifs; Aminoimidazole Carboxamide; Biological Evolution; Catalysis; Computational Biology; Escherichia coli; Glycosides; Histidine; Imidazoles; Molecular Conformation; Pentose Phosphate Pathway; Phylogeny; Purines; Ribonucleotides; Ribose | 2018 |
Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
Topics: Aminohydrolases; Aminoimidazole Carboxamide; beta Catenin; Carcinogenesis; Cell Line; Cell Line, Tumor; Drug Resistance, Neoplasm; Folic Acid; Gefitinib; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lung Neoplasms; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multifunctional Enzymes; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Purines; Ribonucleotides | 2019 |
A Fairy Chemical, Imidazole-4-carboxamide, is Produced on a Novel Purine Metabolic Pathway in Rice.
Topics: Aminoimidazole Carboxamide; Arabidopsis; Gene Expression Profiling; Metabolic Networks and Pathways; Oryza; Purines | 2019 |
Pathway-specific effects of ADSL deficiency on neurodevelopment.
Topics: Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Animals; Autism Spectrum Disorder; Autistic Disorder; Cell Cycle; Cell Cycle Proteins; Cell Line; Chickens; Ciliopathies; DNA Damage; Humans; Microcephaly; Microtubule-Associated Proteins; Neurogenesis; Phenotype; Phosphoproteins; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribonucleotides; Zebrafish | 2022 |