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aminoimidazole carboxamide and palmitic acid

aminoimidazole carboxamide has been researched along with palmitic acid in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.00)18.2507
2000's12 (40.00)29.6817
2010's15 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hardie, DG; Kurth, EJ; Merrill, GF; Winder, WW1
Blázquez, C; Carling, D; de Ceballos, ML; Guzmán, M; Woods, A1
Dagher, Z; Ido, Y; Ruderman, N; Tornheim, K2
Raney, MA; Todd, MK; Turcotte, LP; Yee, AJ1
Ceddia, RB; Fediuc, S; Gaidhu, MP1
Kang, YJ; Kim, JE; Kim, JY; Kim, YW; Lee, IK; Park, SY1
Cooksey, RC; Landaker, E; McClain, D; Park, J; Patti, ME; Ruddock, MW; Stein, A1
Chen, ZP; Dzamko, N; Jørgensen, SB; Kemp, BE; Lynch, GS; Macaulay, SL; Michell, BJ; Oakhill, JS; Ryall, JG; Schertzer, JD; Steel, R; Steinberg, GR; Watt, MJ; Wee, S1
Chabowski, A; Dyck, DJ; Junkin, KA; Mullen, KL; Thrush, AB1
Downs, SM; Klinger, J; Mosey, JL1
Chen, L; Coselli, JS; Hou, X; LeMaire, SA; Li, XN; Shen, YH; Song, J; Wang, XL; Zhang, C; Zhang, L; Zhang, Y1
Armstrong, HE; Jaswal, JS; Keung, W; Lopaschuk, DG; Lopaschuk, GD; Ussher, JR; Wagg, CS1
Abbott, MJ; Edelman, AM; Turcotte, LP1
Bala, M; Buechler, C; Kopp, A; Neumeier, M; Schäffler, A; Sporrer, D; Stögbauer, F; Wanninger, J; Weber, M; Weigert, J; Wurm, S1
Brickey, WJ; Gris, D; Huang, MT; Jha, S; Lei, Y; Ting, JP; Wen, H; Zhang, L1
Bonen, A; Gurd, BJ; Holloway, GP; Yoshida, Y1
Holst, JJ; Kappe, C; Patrone, C; Sjöholm, A; Zhang, Q1
Dong, H; Huang, L; Lin, L; Lin, N; Lu, J; Tan, J; Wang, Q; Zheng, F1
Barroso, E; Coll, T; Gómez-Foix, AM; Palomer, X; Salmerón, E; Salvadó, L; Vázquez-Carrera, M1
Brüne, B; Kemmerer, M; Namgaladze, D; von Knethen, A1
Jackson, KC; Schuh, RA; Spangenburg, EE1
Jehle, AW; Kampe, K; Mundel, P; Orellana, JM; Sieber, J1
Huang, F; Kou, J; Li, J; Liu, B; Liu, K; Qi, L; Sun, Y; Wang, M; Xiao, N1
Hong, SW; Lee, J; Lee, WY; Oh, KW; Park, CY; Park, SE; Park, SW; Rhee, EJ1
Fu, L; Liu, X; Niu, Y; Wang, T; Yuan, H1
Adrian, L; Böhm, M; Heeren, J; Laufs, U; Lenski, M; Tödter, K1
Kar, B; Roy, P; Sharma, AK; Varshney, R; Verma, P1
Hosaka, T; Ishida, H; Kitahara, A; Kondo, T; Morita, N; Murashima, T; Onuma, H; Sumitani, Y; Takahashi, K; Tanaka, T1
Battson, ML; Cox-York, KA; Gentile, CL; Lee, DM; Sevits, KJ; Wei, Y1

Other Studies

30 other study(ies) available for aminoimidazole carboxamide and palmitic acid

ArticleYear
AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Acetyl-CoA Carboxylase; Adenine Nucleotides; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cattle; Enzyme Activation; Erythrocytes; Glucose; Hindlimb; Insulin; Kinetics; Male; Malonyl Coenzyme A; Multienzyme Complexes; Muscle, Skeletal; Palmitic Acid; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Ribonucleosides; Ribonucleotides; Serum Albumin, Bovine

1997
The AMP-activated protein kinase is involved in the regulation of ketone body production by astrocytes.
    Journal of neurochemistry, 1999, Volume: 73, Issue:4

    Topics: Aminoimidazole Carboxamide; Animals; Animals, Newborn; Astrocytes; Carnitine O-Palmitoyltransferase; Cells, Cultured; Cerebral Cortex; Cholesterol; Cyclic AMP-Dependent Protein Kinases; Homeostasis; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Ketone Bodies; Male; Microdialysis; Palmitic Acid; Rats; Rats, Wistar; Ribonucleotides

1999
The effect of AMP-activated protein kinase and its activator AICAR on the metabolism of human umbilical vein endothelial cells.
    Biochemical and biophysical research communications, 1999, Volume: 265, Issue:1

    Topics: Acetyl-CoA Carboxylase; Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Glucose; Glycolysis; Humans; Hypoglycemic Agents; Kinetics; Multienzyme Complexes; Palmitic Acid; Protein Serine-Threonine Kinases; Ribonucleotides; Umbilical Veins

1999
Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells.
    Circulation research, 2001, Jun-22, Volume: 88, Issue:12

    Topics: 3-O-Methylglucose; Acetyl-CoA Carboxylase; Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Caprylates; Carnitine; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Energy Metabolism; Enzyme Activation; Fatty Acids; Glucose; Glycolysis; Humans; Intracellular Fluid; Malonyl Coenzyme A; Multienzyme Complexes; Oxidation-Reduction; Palmitic Acid; Protein Serine-Threonine Kinases; Ribonucleotides; Tritium; Umbilical Veins

2001
AMPK activation is not critical in the regulation of muscle FA uptake and oxidation during low-intensity muscle contraction.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:3

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Electric Stimulation; Enzyme Activation; Fatty Acids; Glucose; Hypoglycemic Agents; Lactic Acid; Male; Malonyl Coenzyme A; Multienzyme Complexes; Muscle Contraction; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Ribonucleotides

2005
Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells.
    Journal of lipid research, 2006, Volume: 47, Issue:2

    Topics: Acetyl-CoA Carboxylase; Adenosine Monophosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carbon Dioxide; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Multienzyme Complexes; Muscle Fibers, Skeletal; Oxidation-Reduction; Palmitic Acid; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Ribonucleotides

2006
AMP-activated protein kinase activation by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) inhibits palmitate-induced endothelial cell apoptosis through reactive oxygen species suppression.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:3

    Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Apoptosis; Cattle; Cells, Cultured; Endothelial Cells; Enzyme Activation; Guanosine Diphosphate; Ion Channels; Mitochondrial Proteins; p38 Mitogen-Activated Protein Kinases; Palmitic Acid; Reactive Oxygen Species; Ribonucleotides; Uncoupling Protein 2

2008
Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.
    Journal of biochemistry, 2008, Volume: 144, Issue:5

    Topics: Aminoimidazole Carboxamide; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme Activation; Enzyme Inhibitors; Epoxy Compounds; Extracellular Signal-Regulated MAP Kinases; Fatty Acids; Fatty Acids, Nonesterified; Forkhead Transcription Factors; Glycogen Synthase Kinase 3; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Liver; Liver Neoplasms; Mice; Mice, Knockout; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Palmitic Acid; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Receptor, Insulin; Ribonucleotides; Signal Transduction; Triazenes

2008
AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.
    The Journal of physiology, 2008, Dec-01, Volume: 586, Issue:23

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Immunoblotting; Malonyl Coenzyme A; Mice; Mice, Inbred Strains; Mice, Transgenic; Motor Activity; Muscle Contraction; Muscle, Skeletal; Oxidation-Reduction; Palmitic Acid; Phosphorylation; Ribonucleotides; Signal Transduction; Sterol Esterase

2008
Resistin acutely impairs insulin-stimulated glucose transport in rodent muscle in the presence, but not absence, of palmitate.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:4

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biological Transport; Ceramides; Enzyme Activators; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Female; Fumonisins; Glucose; In Vitro Techniques; Insulin; Muscle, Skeletal; Palmitic Acid; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resistin; Ribonucleotides; Time Factors

2009
Fatty acid oxidation and meiotic resumption in mouse oocytes.
    Molecular reproduction and development, 2009, Volume: 76, Issue:9

    Topics: 4-Butyrolactone; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Cerulenin; Cumulus Cells; Epoxy Compounds; Fatty Acids; Female; Malonyl Coenzyme A; Meiosis; Mice; Mice, Inbred C57BL; Oocytes; Oxidation-Reduction; Palmitic Acid; Ribonucleotides

2009
Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin.
    Diabetes, 2009, Volume: 58, Issue:10

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Aorta; Apolipoproteins E; DNA Primers; Endothelium, Vascular; Fatty Acids; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Male; Mice; Mice, Knockout; Palmitic Acid; Plasmids; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotides; RNA, Messenger; RNA, Small Interfering; Thioredoxins; Up-Regulation

2009
Role of the atypical protein kinase Czeta in regulation of 5'-AMP-activated protein kinase in cardiac and skeletal muscle.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biguanides; Cells, Cultured; Muscle Fibers, Skeletal; Muscle, Skeletal; Myocardium; Myocytes, Cardiac; Palmitic Acid; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Ribonucleotides

2009
CaMKK is an upstream signal of AMP-activated protein kinase in regulation of substrate metabolism in contracting skeletal muscle.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:6

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Caffeine; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Kinase; CD36 Antigens; Energy Metabolism; Enzyme Activation; Enzyme Activators; Glucose; Glucose Transporter Type 4; Hindlimb; Male; Muscle Contraction; Muscle, Skeletal; Naphthalimides; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Perfusion; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Wistar; Ribonucleotides

2009
Adiponectin downregulates galectin-3 whose cellular form is elevated whereas its soluble form is reduced in type 2 diabetic monocytes.
    FEBS letters, 2009, Nov-19, Volume: 583, Issue:22

    Topics: Adiponectin; Adult; Aged; Aged, 80 and over; Aminoimidazole Carboxamide; Body Mass Index; Cells, Cultured; Cholesterol; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Galectin 3; Humans; Immunoblotting; Male; Metformin; Middle Aged; Monocytes; Oleic Acid; Palmitic Acid; Pyrazoles; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotides; Solubility; Time Factors

2009
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.
    Nature immunology, 2011, Volume: 12, Issue:5

    Topics: Aminoimidazole Carboxamide; Animals; Autophagy; Carrier Proteins; Caspase 1; Dietary Fats; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Inflammasomes; Insulin Resistance; Interleukin-1beta; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; NLR Family, Pyrin Domain-Containing 3 Protein; Oligopeptides; Palmitic Acid; Reactive Oxygen Species; Ribonucleotides; Signal Transduction

2011
In mammalian muscle, SIRT3 is present in mitochondria and not in the nucleus; and SIRT3 is upregulated by chronic muscle contraction in an adenosine monophosphate-activated protein kinase-independent manner.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:5

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blotting, Western; Carnitine O-Palmitoyltransferase; Cell Nucleus; Citrate (si)-Synthase; Electric Stimulation; Enoyl-CoA Hydratase; Female; Mitochondria, Muscle; Muscle Contraction; Palmitic Acid; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Ribonucleotides; RNA-Binding Proteins; Sirtuin 1; Transcription Factors; Up-Regulation

2012
Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells.
    Journal of gastroenterology, 2013, Volume: 48, Issue:3

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Animals; Apoptosis; Caspase 3; Cytoprotection; Enteroendocrine Cells; Glucagon-Like Peptide 1; Hypoglycemic Agents; MAP Kinase Kinase 4; Metformin; Mice; Palmitic Acid; Phosphorylation; Protein Kinases; Ribonucleotides; Tumor Cells, Cultured

2013
Palmitate causes endoplasmic reticulum stress and apoptosis in human mesenchymal stem cells: prevention by AMPK activator.
    Endocrinology, 2012, Volume: 153, Issue:11

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Apoptosis; Cells, Cultured; Endoplasmic Reticulum Stress; Humans; Hypoglycemic Agents; Mesenchymal Stem Cells; p38 Mitogen-Activated Protein Kinases; Palmitic Acid; Phosphorylation; Ribonucleotides

2012
Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.
    Diabetologia, 2013, Volume: 56, Issue:6

    Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biphenyl Compounds; Cell Line; Cell Nucleus; Chromatography, High Pressure Liquid; Endoplasmic Reticulum; Humans; Inflammation; Insulin Resistance; Lipids; Mice; Muscle Cells; Muscle, Skeletal; NF-kappa B; Oleic Acid; Palmitic Acid; Pyrones; Ribonucleotides; Signal Transduction; Thiophenes

2013
AICAR inhibits PPARγ during monocyte differentiation to attenuate inflammatory responses to atherogenic lipids.
    Cardiovascular research, 2013, Jun-01, Volume: 98, Issue:3

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Atherosclerosis; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Enzyme Activation; Enzyme Activators; Gene Expression Regulation; Humans; Inflammation; Interleukin-4; JNK Mitogen-Activated Protein Kinases; Lipoproteins, LDL; Macrophages; Monocytes; Palmitic Acid; Phenotype; PPAR gamma; Ribonucleotides; RNA Interference; RNA, Messenger; Transfection

2013
AICAR inhibits oxygen consumption by intact skeletal muscle cells in culture.
    Journal of physiology and biochemistry, 2013, Volume: 69, Issue:4

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Line; Fatty Acids; Glucose; Mice; Mitochondria, Muscle; Muscle Fibers, Skeletal; Oxidation-Reduction; Oxygen; Oxygen Consumption; Palmitic Acid; Phosphorylation; Ribonucleotides

2013
Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2.
    American journal of physiology. Renal physiology, 2014, Feb-15, Volume: 306, Issue:4

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carnitine O-Palmitoyltransferase; Cells, Cultured; Fatty Acids; Lipid Metabolism; Mice; Palmitic Acid; Podocytes; Ribonucleotides

2014
Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1.
    Pharmacological research, 2014, Volume: 89

    Topics: Adipokines; Adipose Tissue; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Aorta; Culture Media, Conditioned; Diet; Fructose; Metformin; NF-kappa B; Palmitic Acid; Rats; Resveratrol; Ribonucleotides; Sirtuin 1; Sodium Salicylate; Stilbenes; Vasodilation

2014
AMP-activated protein kinase suppresses the expression of LXR/SREBP-1 signaling-induced ANGPTL8 in HepG2 cells.
    Molecular and cellular endocrinology, 2015, Oct-15, Volume: 414

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angiopoietins; Hep G2 Cells; Hepatocytes; Humans; Hydrocarbons, Fluorinated; Liver X Receptors; Orphan Nuclear Receptors; Palmitic Acid; Phosphorylation; PPAR alpha; Ribonucleotides; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Sulfonamides; Tunicamycin

2015
AMP-activated protein kinase-mediated expression of heat shock protein beta 1 enhanced insulin sensitivity in the skeletal muscle.
    FEBS letters, 2017, Volume: 591, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Line; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Gene Expression Regulation; Glucose; Histone Deacetylases; HSP27 Heat-Shock Proteins; Insulin; Insulin Resistance; Mice, Inbred C57BL; Muscle, Skeletal; Palmitic Acid; Phenotype; Proteomics; Ribonucleotides; Tandem Mass Spectrometry

2017
AMPK Prevents Palmitic Acid-Induced Apoptosis and Lipid Accumulation in Cardiomyocytes.
    Lipids, 2017, Volume: 52, Issue:9

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Cardiomegaly; Cell Line; Cells, Cultured; Fatty Acids; Lipid Metabolism; Mice, Inbred C57BL; Myocytes, Cardiac; Palmitic Acid; Phosphorylation; Rats, Sprague-Dawley; Ribonucleotides

2017
Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis.
    The FEBS journal, 2017, Volume: 284, Issue:24

    Topics: Aminoimidazole Carboxamide; Animals; Bacterial Proteins; Calorimetry, Differential Scanning; Cell Division; Glucose; Hydroxymethyl and Formyl Transferases; Inosine Monophosphate; Mice; Multienzyme Complexes; Mutation; NIH 3T3 Cells; Nucleotide Deaminases; Palmitic Acid; Protein Conformation; Protein Domains; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staphylococcus lugdunensis; Wound Healing

2017
Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK.
    Journal of diabetes research, 2018, Volume: 2018

    Topics: 3T3-L1 Cells; Adenylate Kinase; Adipocytes; Aminoimidazole Carboxamide; Animals; Chemokine CCL2; Inflammation; Metformin; Mice; NF-kappa B; Palmitic Acid; Phosphorylation; Ribonucleotides; Signal Transduction; Triglycerides

2018
Monounsaturated fatty acids protect against palmitate-induced lipoapoptosis in human umbilical vein endothelial cells.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Apoptosis; Cardiovascular Diseases; Cell Survival; Dietary Fats; Endothelium, Vascular; Fatty Acids, Monounsaturated; Human Umbilical Vein Endothelial Cells; Humans; Palmitic Acid; Pyrazoles; Pyrimidines; Ribonucleotides

2019