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aminoimidazole carboxamide and glycogen

aminoimidazole carboxamide has been researched along with glycogen in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.17)18.7374
1990's3 (6.25)18.2507
2000's30 (62.50)29.6817
2010's13 (27.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dietzler, DN; Leckie, MP; Porter, SE; Tieber, VL1
Pasque, MK; Wechsler, AS1
Leighton, B; Radda, GK; Young, ME1
Erion, MD; Gruber, HE; Van den Berghe, G; Vincent, MF1
Holmes, BF; Kurth-Kraczek, EJ; Winder, WW1
Hardie, DG; Hellsten, Y; Jørgensen, SB; Richter, EA; Wojtaszewski, JF1
Chibalin, AV; Fernström, M; Fiedler, M; Galuska, D; Ryder, JW; Song, XM; Wallberg-Henriksson, H; Zierath, JR1
Aschenbach, WG; Fujii, N; Goodyear, LJ; Hirshman, MF; Howlett, KF; Sakamoto, K1
Hansen, BF; Olsen, GS1
Carling, D; Fryer, LG; Halse, R; McCormack, JG; Yeaman, SJ1
Barton, ER; Birnbaum, MJ; Mu, J1
Allard, MF; Brownsey, RW; Longnus, SL; Parsons, HL; Wambolt, RB1
Goodyear, LJ; Musi, N1
Tabata, I; Terada, S1
Andreelli, F; Birk, JB; Frøsig, C; Jørgensen, SB; Richter, EA; Schjerling, P; Vaulont, S; Viollet, B; Wojtaszewski, JF1
Lehrman, MA; Shang, J1
Burcelin, R; Knauf, C; Perrin, C1
Andreelli, F; Birk, JB; Hansen, BF; Hardie, DG; Jørgensen, SB; Nielsen, JN; Olsen, GS; Richter, EA; Schjerling, P; Vaulont, S; Viollet, B; Wojtaszewski, JF1
Al-Khalili, L; Forsgren, M; Kannisto, K; Krook, A; Lönnqvist, F; Zierath, JR1
Andreelli, F; Birk, JB; Hellsten, Y; Jørgensen, SB; Neufer, PD; Pilegaard, H; Richter, EA; Schjerling, P; Vaulont, S; Viollet, B; Wojtaszewski, JF1
Camacho, RC; Donahue, EP; James, FD; Lacy, DB; Wasserman, DH1
Fujii, N; Goodyear, LJ; Hirshman, MF; Peter, LE; Pomerleau, JM; Yu, H1
Alford, FP; Chen, ZP; Christopher, M; Kemp, B; Rantzau, C; Snow, R1
Ceddia, RB; Fediuc, S; Gaidhu, MP1
Ebihara, K; Fushiki, T; Hayashi, T; Hosoda, K; Inoue, G; Masuzaki, H; Miyamoto, L; Nakano, M; Nakao, K; Ogawa, Y; Tanaka, S; Toyoda, T; Yonemitsu, S1
Litherland, GJ; Morris, NJ; Walker, M; Yeaman, SJ1
Alquier, T; Kahn, BB; Kawashima, J; Tsuji, Y1
Bonen, A; Febbraio, M; Glatz, JF; Habets, DD; Han, XX; Luiken, JJ1
Baar, K; Babraj, JA; Cuthbertson, DJ; Green, KA; Hardie, DG; Leese, GP; Mustard, KJ; Rennie, MJ; Sutherland, C; Thomason-Hughes, M; Towler, MC; Wackerhage, H1
Alford, FP; Christopher, M; Rantzau, C1
Kemp, BE; Lee-Young, RS; Linden, KC; Manimmanakorn, A; McConell, GK; Wadley, GD1
Albers, P; Glatz, JF; Jeppesen, J; Kiens, B; Luiken, JJ1
Blair, DR; Cartee, GD; Funai, K; Schweitzer, GG1
Bøtker, HE; Jessen, N; Kristiansen, SB; Lund, S; Løfgren, B; Nielsen, TT; Nielsen-Kudsk, JE; Schmitz, O; Solskov, L1
Birk, JB; Jensen, TE; Jeppesen, J; Jørgensen, SB; Maarbjerg, SJ; Richter, EA; Rose, AJ; Schjerling, P; Treebak, JT; Wojtaszewski, JF1
Fisslthaler, B; Fleming, I; Kehl, F; Lange, M; Lotz, C; Pociej, J; Redel, A; Roewer, N; Smul, TM; Stumpner, J1
Biensø, RS; Fentz, J; Jeppesen, J; Kiens, B; Knudsen, JG; Leick, L; Pilegaard, H; Wojtaszewski, JF1
Canny, BJ; Clarke, IJ; Henry, BA; Laker, RC; McConell, GK; Wadley, GD1
Hunter, RW; Sakamoto, K; Treebak, JT; Wojtaszewski, JF1
Andres, AM; Hui, ST; Ratliff, EP; Sachithanantham, S1
Catus, SL; Gibbs, ME; Hutchinson, DS; Merlin, J; Summers, RJ1
Birk, JB; Friedrichsen, M; Mortensen, B; Pehmøller, C; Wojtaszewski, JF1
Bikopoulos, G; Ceddia, RB; Curi, R; Hung, S; Patterson, JD; Pistor, KE; Vitzel, KF1
Foretz, M; Hallén, S; Kviklyte, S; Lai, YC; Lantier, L; Rider, MH; Vertommen, D; Viollet, B1
Albuquerque, GG; Anhê, GF; Bordin, S; Caperuto, LC; Gomes, PR; Lellis-Santos, C; Nachbar, RT; Nogueira, TC; Pantaleão, LC; Rodrigues, SC; Torres-Leal, FL1
Chen, G; Lao, M; Li, Z; Liang, L; Qiu, Q; Shi, M; Wang, C; Wang, J; Xiao, Y; Xu, H; Yang, X; Ye, Y; Yu, Y; Zhang, H1
Anzueto, DG; Blanco, CL; DeFronzo, RA; Gastaldelli, A; Javors, MA; Liang, H; McCurnin, DC; Musi, N; Seidner, SR; Winter, LA1
Al-Hasani, H; Chadt, A; de Wendt, C; Jørgensen, NO; Kido, K; Kjøbsted, R; Larsen, JK; Wojtaszewski, JFP1

Reviews

4 review(s) available for aminoimidazole carboxamide and glycogen

ArticleYear
Metabolic intervention to affect myocardial recovery following ischemia.
    Annals of surgery, 1984, Volume: 200, Issue:1

    Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; Animals; Citric Acid Cycle; Coronary Circulation; Coronary Disease; Fructosediphosphates; Glucose; Glycogen; Heart; Humans; Inosine; Myocardium; Oxidative Phosphorylation; Ribonucleosides; Ribose

1984
Selective suppression of AMP-activated protein kinase in skeletal muscle: update on 'lazy mice'.
    Biochemical Society transactions, 2003, Volume: 31, Issue:Pt 1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Enzyme Inhibitors; Glycogen; Glycogen Synthase; Hypertrophy; Hypoxia; Mice; Multienzyme Complexes; Muscle, Skeletal; Mutation; Phenotype; Physical Conditioning, Animal; Protein Serine-Threonine Kinases; Ribonucleotides; Time Factors; Transcription, Genetic

2003
AMP-activated protein kinase and muscle glucose uptake.
    Acta physiologica Scandinavica, 2003, Volume: 178, Issue:4

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Exercise; Glucose; Glycogen; Humans; Hypoglycemic Agents; Insulin; Metformin; Multienzyme Complexes; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Nutritional Status; Protein Serine-Threonine Kinases; Rats; Ribonucleotides

2003
Exercise-induced AMPK activity in skeletal muscle: role in glucose uptake and insulin sensitivity.
    Molecular and cellular endocrinology, 2013, Feb-25, Volume: 366, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biological Transport; Energy Metabolism; Exercise; Glucose; Glycogen; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Muscle, Skeletal; Oxidation-Reduction; Ribonucleotides; Signal Transduction

2013

Trials

1 trial(s) available for aminoimidazole carboxamide and glycogen

ArticleYear
5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men.
    Diabetes, 2007, Volume: 56, Issue:8

    Topics: Adult; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biopsy; Blood Glucose; Deoxyglucose; Glycogen; Health; Hormones; Humans; Insulin; Isoenzymes; Lactic Acid; Male; Multienzyme Complexes; Muscle, Skeletal; Protein Serine-Threonine Kinases; Ribonucleosides; Time Factors

2007

Other Studies

43 other study(ies) available for aminoimidazole carboxamide and glycogen

ArticleYear
Regulation of the basal and cyclic AMP-stimulated rates of glycogen synthesis in Escherichia coli by an intermediate of purine biosynthesis.
    Biochemical and biophysical research communications, 1981, Apr-30, Volume: 99, Issue:4

    Topics: Aminoimidazole Carboxamide; Azaserine; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cyclic AMP; Escherichia coli; Glycine; Glycogen; Ligases; Purines; Ribonucleotides

1981
Activation of glycogen phosphorylase and glycogenolysis in rat skeletal muscle by AICAR--an activator of AMP-activated protein kinase.
    FEBS letters, 1996, Mar-11, Volume: 382, Issue:1-2

    Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Enzyme Activation; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Male; Multienzyme Complexes; Muscle, Skeletal; Phosphorylases; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Ribonucleotides

1996
Hypoglycaemic effect of AICAriboside in mice.
    Diabetologia, 1996, Volume: 39, Issue:10

    Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; Animals; Blood Glucose; Fasting; Glucose; Glycogen; Hypoglycemic Agents; Lactates; Liver; Male; Mice; Mice, Inbred Strains; Muscle, Skeletal; Phosphates; Rats; Ribonucleotides

1996
Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:5

    Topics: Aminoimidazole Carboxamide; Animals; Blood Glucose; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Activators; Glucose Transporter Type 4; Glycogen; Hexokinase; Hypoglycemic Agents; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Ribonucleotides

1999
Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle.
    Diabetes, 2002, Volume: 51, Issue:2

    Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animal Feed; Animals; Deoxyglucose; Glycogen; Glycogen Synthase; Isoenzymes; Male; Motor Activity; Multienzyme Complexes; Muscle, Skeletal; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Ribonucleosides; Ribonucleotides; Swimming

2002
5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice.
    Diabetologia, 2002, Volume: 45, Issue:1

    Topics: Aminoimidazole Carboxamide; Animals; Biological Transport; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Glucose Tolerance Test; Glycogen; Homeostasis; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Resistance; Liver; Liver Glycogen; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; Obesity; Ribonucleotides

2002
Effect of AICAR treatment on glycogen metabolism in skeletal muscle.
    Diabetes, 2002, Volume: 51, Issue:3

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Enzyme Activation; Glucose; Glycogen; Glycogen Phosphorylase; Glycogen Synthase; Isoenzymes; Kinetics; Lactic Acid; Male; Multienzyme Complexes; Muscle, Skeletal; Phosphorylation; Protein Serine-Threonine Kinases; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ribonucleotides

2002
AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 283, Issue:5

    Topics: Adenylate Kinase; Amino Acid Sequence; Aminoimidazole Carboxamide; Animals; Enzyme Activation; Fatty Acids, Nonesterified; Glycogen; Hypoglycemic Agents; Insulin Resistance; Male; Molecular Sequence Data; Muscle, Skeletal; Palmitates; Rats; Rats, Wistar; Ribonucleotides

2002
Regulation of glycogen synthase by glucose and glycogen: a possible role for AMP-activated protein kinase.
    Diabetes, 2003, Volume: 52, Issue:1

    Topics: Amides; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cells, Cultured; Enzyme Activation; Glucose; Glycogen; Glycogen Phosphorylase; Glycogen Synthase; Humans; Hydrogen Peroxide; Indoles; Isoenzymes; Multienzyme Complexes; Myoblasts; Protein Serine-Threonine Kinases; Ribonucleotides

2003
5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside (AICAR) stimulates myocardial glycogenolysis by allosteric mechanisms.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:4

    Topics: Adenylate Kinase; Allosteric Regulation; Aminoimidazole Carboxamide; Animals; Enzyme Activation; Glycogen; Glycogen Phosphorylase; Glycogen Synthase; Heart; Male; Myocardium; Rats; Rats, Sprague-Dawley; Ribonucleotides; Stereoisomerism; Time Factors

2003
Effects of acute bouts of running and swimming exercise on PGC-1alpha protein expression in rat epitrochlearis and soleus muscle.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 286, Issue:2

    Topics: Aging; Aminoimidazole Carboxamide; Animals; Caffeine; Forelimb; Glycogen; Male; Muscle, Skeletal; Protein Isoforms; Rats; Rats, Sprague-Dawley; Ribonucleotides; Running; Swimming; Time Factors; Transcription Factors

2004
Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.
    The Journal of biological chemistry, 2004, Jan-09, Volume: 279, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Deoxyglucose; Dose-Response Relationship, Drug; Female; Glucose; Glucose Tolerance Test; Glycogen; Immunoblotting; Insulin; Male; Mice; Mice, Knockout; Models, Genetic; Multienzyme Complexes; Muscle, Skeletal; Muscles; Precipitin Tests; Protein Isoforms; Protein Serine-Threonine Kinases; Ribonucleotides; Time Factors

2004
Activation of glycogen phosphorylase with 5-aminoimidazole-4-carboxamide riboside (AICAR). Assessment of glycogen as a precursor of mannosyl residues in glycoconjugates.
    The Journal of biological chemistry, 2004, Mar-26, Volume: 279, Issue:13

    Topics: Amides; Aminoimidazole Carboxamide; Binding Sites; Caffeine; Catalysis; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP; Cyclic GMP; Enzyme Activation; Fibroblasts; Glycogen; Glycogen Phosphorylase; Humans; Hypoglycemic Agents; Indoles; Lipid Metabolism; Mannose; Metformin; Oligosaccharides; Phosphorylation; Protein Binding; Ribonucleotides; Skin; Time Factors

2004
Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, controls muscle glycogen synthesis.
    Endocrinology, 2004, Volume: 145, Issue:9

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Fasting; Glucose; Glycogen; Hyperinsulinism; Hypoglycemic Agents; Hypothalamus; Injections, Intraventricular; Insulin; Male; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Muscle, Skeletal; Phosphorylation; Protein Serine-Threonine Kinases; Ribonucleosides

2004
The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading.
    Diabetes, 2004, Volume: 53, Issue:12

    Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Glucose; Glycogen; Glycogen Synthase; Glycogen Synthase Kinases; Hindlimb; Male; Mice; Muscle, Skeletal; Phosphorylation; Rats; Rats, Wistar; Ribonucleotides

2004
Enhanced insulin-stimulated glycogen synthesis in response to insulin, metformin or rosiglitazone is associated with increased mRNA expression of GLUT4 and peroxisomal proliferator activator receptor gamma co-activator 1.
    Diabetologia, 2005, Volume: 48, Issue:6

    Topics: Adult; Aminoimidazole Carboxamide; Biopsy; Cells, Cultured; Female; Glucose; Glucose Transporter Type 4; Glycogen; Humans; Insulin; Male; Metformin; Middle Aged; Monosaccharide Transport Proteins; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Reference Values; Ribonucleotides; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription Factors

2005
Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9

    Topics: Acetyl-CoA Carboxylase; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Female; Gene Expression Regulation; Glycogen; Hexokinase; Inosine Monophosphate; Ion Channels; Male; Mice; Mice, Knockout; Mitochondrial Proteins; Multienzyme Complexes; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Protein Kinases; Protein Serine-Threonine Kinases; Ribonucleotides; RNA, Messenger; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Uncoupling Protein 3

2005
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside renders glucose output by the liver of the dog insensitive to a pharmacological increment in insulin.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 289, Issue:6

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Arteries; Blood Glucose; Dogs; Female; Glucose; Glucose Clamp Technique; Glycogen; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Kinetics; Liver; Male; Multienzyme Complexes; Phosphorylation; Protein Serine-Threonine Kinases; Ribonucleotides

2005
Muscle-specific overexpression of wild type and R225Q mutant AMP-activated protein kinase gamma3-subunit differentially regulates glycogen accumulation.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:3

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Deoxyglucose; Female; Gene Expression; Glucose; Glycogen; Glycogen Phosphorylase; Glycogen Synthase; Hypoglycemic Agents; Insulin; Isoenzymes; Male; Mice; Mice, Transgenic; Multienzyme Complexes; Muscle, Skeletal; Mutation; Myocardium; Phenformin; Protein Kinases; Protein Serine-Threonine Kinases; Ribonucleotides

2006
Impact of in vivo fatty acid oxidation blockade on glucose turnover and muscle glucose metabolism during low-dose AICAR infusion.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:5

    Topics: Acetyl-CoA Carboxylase; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Epoxy Compounds; Fatty Acids; Glucagon; Glucose; Glucosephosphate Dehydrogenase; Glycogen; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Multienzyme Complexes; Muscle, Skeletal; Oxidation-Reduction; Propionates; Protein Serine-Threonine Kinases; Ribonucleotides; Serine

2006
Inhibition of insulin-stimulated glycogen synthesis by 5-aminoimidasole-4-carboxamide-1-beta-d-ribofuranoside-induced adenosine 5'-monophosphate-activated protein kinase activation: interactions with Akt, glycogen synthase kinase 3-3alpha/beta, and glycog
    Endocrinology, 2006, Volume: 147, Issue:11

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Glycogen; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Insulin; Lactic Acid; Male; Multienzyme Complexes; Muscle, Skeletal; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Ribonucleotides

2006
Effect of acute activation of 5'-AMP-activated protein kinase on glycogen regulation in isolated rat skeletal muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:3

    Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Glycogen; Glycogen Phosphorylase; Glycogen Synthase; Glycolysis; In Vitro Techniques; Insulin; Lactic Acid; Male; Multienzyme Complexes; Muscle Contraction; Muscle, Skeletal; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Ribonucleosides; Ribonucleotides; Time Factors

2007
Role of glycogen content in insulin resistance in human muscle cells.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Glycogen; Glycogen Synthase; Glycogen Synthase Kinase 3; Humans; Insulin; Insulin Resistance; Myoblasts, Skeletal; Phosphorylation; Protein Kinases; Protein Transport; Proto-Oncogene Proteins c-akt; Ribonucleotides; Signal Transduction; Time Factors

2007
Role of hypothalamic adenosine 5'-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia.
    Endocrinology, 2007, Volume: 148, Issue:3

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Brain Chemistry; Deoxyglucose; Eating; Glucose; Glycogen; Hypoglycemia; Hypothalamus; Male; Multienzyme Complexes; Neurosecretory Systems; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Recurrence; Ribonucleotides

2007
A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:6

    Topics: Aminoimidazole Carboxamide; Animals; Blood Glucose; CD36 Antigens; Diglycerides; Esterification; Fatty Acid Transport Proteins; Fatty Acids; Glycogen; Hindlimb; Insulin; Mice; Mice, Knockout; Mitochondrial Proteins; Muscle, Skeletal; Oxidation-Reduction; Palmitates; Phospholipids; Ribonucleotides; Triglycerides

2007
Contrasting effects of exercise, AICAR, and increased fatty acid supply on in vivo and skeletal muscle glucose metabolism.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 104, Issue:2

    Topics: Aminoimidazole Carboxamide; Animals; Blood Glucose; Dogs; Energy Metabolism; Fat Emulsions, Intravenous; Fatty Acids; Glucose; Glucose-6-Phosphate; Glycerol; Glycogen; Hypoglycemic Agents; Infusions, Parenteral; Lactic Acid; Liver; Male; Muscle Contraction; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Physical Exertion; Ribonucleotides; Time Factors

2008
Differential attenuation of AMPK activation during acute exercise following exercise training or AICAR treatment.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:5

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Animals; Body Weight; Eating; Enzyme Activators; Glucose; Glycogen; Male; Muscle, Skeletal; Phosphorylation; Physical Exertion; Protein Kinases; Rats; Rats, Sprague-Dawley; Ribonucleotides; Signal Transduction; Time Factors

2008
Contractions but not AICAR increase FABPpm content in rat muscle sarcolemma.
    Molecular and cellular biochemistry, 2009, Volume: 326, Issue:1-2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; CD36 Antigens; Fatty Acid-Binding Proteins; Glucose Transporter Type 4; Glycogen; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Contraction; Muscle, Skeletal; Phosphorylation; Rats; Ribonucleotides; Sarcolemma

2009
A myosin II ATPase inhibitor reduces force production, glucose transport, and phosphorylation of AMPK and TBC1D1 in electrically stimulated rat skeletal muscle.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 296, Issue:5

    Topics: 3-O-Methylglucose; Adenosine Triphosphate; Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Electric Stimulation; Enzyme Inhibitors; Glycogen; Glycogen Synthase Kinase 3; Hypoglycemic Agents; Immunoblotting; In Vitro Techniques; Male; Muscle Contraction; Muscle, Skeletal; Myosins; Phosphocreatine; Phosphorylation; Proteins; Rats; Rats, Wistar; Ribonucleotides; Sulfonamides; Toluene

2009
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases myocardial glucose uptake during reperfusion and induces late pre-conditioning: potential role of AMP-activated protein kinase.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 105, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Glucose; Glucose Transporter Type 4; Glycogen; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Physical Exertion; Protective Agents; Random Allocation; Rats; Rats, Wistar; Ribonucleotides; Ventricular Pressure

2009
Genetic impairment of AMPKalpha2 signaling does not reduce muscle glucose uptake during treadmill exercise in mice.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:4

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Catheterization; Female; Glucose; Glucose Transporter Type 4; Glycogen; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Muscle, Skeletal; Phosphocreatine; Phosphorylation; Physical Conditioning, Animal; Ribonucleotides; Signal Transduction

2009
Activation of adenosine-monophosphate-activated protein kinase abolishes desflurane-induced preconditioning against myocardial infarction in vivo.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anesthetics, Inhalation; Animals; Body Temperature; Cardiotonic Agents; Desflurane; Electrocardiography; Enzyme Activation; Glycogen; Hemodynamics; Hypoglycemic Agents; Immunoprecipitation; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Myocardial Infarction; Myocardium; Rabbits; Ribonucleotides

2011
PGC-1{alpha} is required for AICAR-induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 299, Issue:3

    Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Blood Glucose; Blotting, Western; CD36 Antigens; Electron Transport Complex IV; Enzyme Activation; Female; Glucose Transporter Type 4; Glycogen; Male; Mice; Mice, Knockout; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotides; RNA, Messenger; Trans-Activators; Transcription Factors

2010
Central infusion of leptin does not increase AMPK signaling in skeletal muscle of sheep.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 300, Issue:2

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animal Structures; Animals; Blood Glucose; Body Weight; Catecholamines; Eating; Fatty Acids, Nonesterified; Female; Glycerol; Glycogen; Growth Hormone; Hydrocortisone; Hypoglycemic Agents; Infusions, Intra-Arterial; Infusions, Intraventricular; Insulin; Leptin; Liver; Muscle, Skeletal; Ovariectomy; Phosphorylation; Protein Subunits; Ribonucleotides; Sheep; Signal Transduction; Subcutaneous Fat

2011
Molecular mechanism by which AMP-activated protein kinase activation promotes glycogen accumulation in muscle.
    Diabetes, 2011, Volume: 60, Issue:3

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Blotting, Western; Glycogen; Glycogen Synthase; Mice; Mice, Transgenic; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphorylation; Ribonucleotides; Signal Transduction

2011
Diminished AMPK signaling response to fasting in thioredoxin-interacting protein knockout mice.
    FEBS letters, 2011, Apr-20, Volume: 585, Issue:8

    Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blotting, Western; Carrier Proteins; Enzyme Activation; Fasting; Glucose; Glucose Transporter Type 1; Glycogen; Hypoglycemic Agents; Insulin; Mice; Mice, Knockout; Muscle, Skeletal; Myocardium; Phosphorylation; Pyruvate Dehydrogenase Complex; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotides; Serine; Signal Transduction; Thioredoxins

2011
α₂-Adrenoceptors activate noradrenaline-mediated glycogen turnover in chick astrocytes.
    Journal of neurochemistry, 2011, Volume: 117, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Aminoimidazole Carboxamide; Animals; Astrocytes; Biotransformation; Cells, Cultured; Chick Embryo; Glucose; Glycogen; Glycogen Synthase Kinase 3; Hypoglycemic Agents; Kinetics; Norepinephrine; Oncogene Protein v-akt; Phosphorylation; Prosencephalon; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotides; Yohimbine

2011
Chronic treatment with the AMP-kinase activator AICAR increases glycogen storage and fatty acid oxidation in skeletal muscles but does not reduce hyperglucagonemia and hyperglycemia in insulin deficient rats.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adenylate Kinase; Adiposity; Aminoimidazole Carboxamide; Animals; Blood Glucose; Epididymis; Fatty Acids; Glucagon; Glycogen; Glycogen Synthase; Glycogen Synthase Kinase 3; Hyperglycemia; Insulin; Male; Muscle, Skeletal; Oxidation-Reduction; Palmitates; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Ribonucleotides; Triglycerides

2013
A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators.
    The Biochemical journal, 2014, Jun-15, Volume: 460, Issue:3

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Biphenyl Compounds; Enzyme Activation; Fatty Acids; Glucose; Glycogen; Male; Mice; Muscle Contraction; Muscle, Skeletal; Pyrones; Rats; Ribonucleotides; Thiophenes

2014
Selective regulation of hepatic lipid metabolism by the AMP-activated protein kinase pathway in late-pregnant rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Nov-01, Volume: 307, Issue:9

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Female; Gene Expression Regulation; Gluconeogenesis; Glycogen; Lipid Metabolism; Liver; Malate Dehydrogenase; Pregnancy; Rats; Rats, Wistar; Ribonucleotides; Signal Transduction; Triglycerides

2014
Glycogen Metabolism and Rheumatoid Arthritis: The Role of Glycogen Synthase 1 in Regulation of Synovial Inflammation
    Frontiers in immunology, 2018, Volume: 9

    Topics: Adult; Aged; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Arthritis, Rheumatoid; Biomarkers; Carbohydrate Metabolism; Cell Movement; Cell Proliferation; Cytokines; Female; Gene Expression; Gene Knockdown Techniques; Glycogen; Glycogen Synthase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Inflammation Mediators; Male; Middle Aged; Ribonucleotides; Synovial Membrane; Synoviocytes

2018
Effects of intravenous AICAR (5-aminoimidazole-4-carboximide riboside) administration on insulin signaling and resistance in premature baboons, Papio sp.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Administration, Intravenous; Aminoimidazole Carboxamide; Animals; Animals, Newborn; Fatty Acids, Nonesterified; Female; Glycogen; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Papio; Random Allocation; Ribonucleotides; RNA, Messenger

2018
TBC1D4 Is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction.
    Diabetes, 2019, Volume: 68, Issue:9

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Glucose; Glycogen; GTPase-Activating Proteins; Insulin; Insulin Resistance; Mice; Mice, Knockout; Muscle Contraction; Muscle, Skeletal; Phosphorylation; Ribonucleotides; Signal Transduction

2019