aminoglutethimide and theophylline

aminoglutethimide has been researched along with theophylline in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's1 (7.14)18.2507
2000's3 (21.43)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chavin, W; Honn, KV1
Butler, MC; Giannina, T; O'Byrne, EM; Sawyer, WK; Steinetz, BG1
Lønning, PE1
Kvinssland, S; Lønning, PE; Ueland, PM1
Jungmann, RA; Leier, DJ1
Bakke, OM; Kvinnsland, S; Lønning, E1
Hori, S; Kizu, J; Terajima, T; Tsuchiya, M; Watanabe, S; Yamakami, J1

Other Studies

14 other study(ies) available for aminoglutethimide and theophylline

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vitro effects of theophylline and aminogluthetimide upon basal and ACTH induced cAMP levels and steroid output by the normal human adrenal gland.
    Acta endocrinologica, 1978, Volume: 88, Issue:2

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Breast Neoplasms; Cyclic AMP; Female; Humans; Hydrocortisone; Middle Aged; Theophylline

1978
Post-implantation termination of pregnancy in rats.
    Contraception, 1976, Volume: 14, Issue:5

    Topics: Abortifacient Agents; Alkaline Phosphatase; Aminoglutethimide; Animals; Cyclofenil; Diethylstilbestrol; Drug Synergism; Embryonic Development; Estradiol; Estradiol Congeners; Estrogen Antagonists; Female; Indomethacin; Organ Size; Pregnancy; Pregnancy, Animal; Progesterone; Prolactin; Prostaglandins; Pyrrolidines; Rats; Theophylline; Uterus

1976
Aminoglutethimide enzyme induction: pharmacological and endocrinological implications.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:4

    Topics: Aminoglutethimide; Antipyrine; Aromatase Inhibitors; Breast Neoplasms; Digitoxin; Drug Interactions; Estrogens; Humans; Theophylline; Warfarin

1990
Aminoglutethimide as an inducer of microsomal enzymes. Part 1: Pharmacological aspects.
    Breast cancer research and treatment, 1986, Volume: 7 Suppl

    Topics: Aminoglutethimide; Antipyrine; Dexamethasone; Digitoxin; Drug Interactions; Enzyme Activation; Humans; Kinetics; Medroxyprogesterone; Medroxyprogesterone Acetate; Microsomes; Theophylline; Warfarin

1986
Adrenocorticotropic hormone and dibutryl adenosine cyclic monophosphate-mediated Ca2+ uptake by rat adrenal glands.
    Biochimica et biophysica acta, 1973, Dec-05, Volume: 329, Issue:2

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Biological Transport; Biological Transport, Active; Bucladesine; Calcium; Calcium Isotopes; Calcium Radioisotopes; Corticosterone; Cycloheximide; Dactinomycin; Female; Hypophysectomy; Inulin; Pituitary Gland; Rats; Spectrophotometry, Atomic; Steroids; Theophylline; Time Factors; Tritium

1973
Effect of aminoglutethimide on antipyrine, theophylline, and digitoxin disposition in breast cancer.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:6

    Topics: Adult; Aged; Aminoglutethimide; Antipyrine; Breast Neoplasms; Chromatography, High Pressure Liquid; Digitoxin; Drug Interactions; Female; Humans; Kinetics; Male; Middle Aged; Theophylline

1984
Anti-inflammatory effect of theophylline in rats and its involvement of the glucocorticoid-glucocorticoid receptor system.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:4

    Topics: Aminoglutethimide; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Glucocorticoids; Hormone Antagonists; Injections, Subcutaneous; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Theophylline

2008