aminoglutethimide has been researched along with rogletimide in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 15 (78.95) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jarman, M; Laughton, CA; McCague, R; McKenna, R; Neidle, S; Rowlands, MG | 1 |
| Foster, AB; Griggs, LJ; Jarman, M; Leung, CS; Rowlands, MG; Wilman, DE | 1 |
| Foster, AB; Jarman, M; Leung, CS; Plevey, RG; Rowlands, MG; Sampson, P; Taylor, GN | 1 |
| Dowsett, M; Jacobs, S; Jones, AL; Lønning, PE; MacNeill, FA; Powles, TJ | 1 |
| McCague, R; Rowlands, MG | 1 |
| McCague, R; Niessen, WM; Poon, GK; Tjaden, UR; van Bakergem, E; van der Greef, J; van der Hoeven, RA | 1 |
| Dowsett, M; Mehta, A; Newton, CJ | 1 |
| Griggs, LJ; Jarman, M; Lewis, IA; McCague, R; Poon, GK | 1 |
| Coombes, RC; Dowsett, M; Griggs, LJ; Haynes, BP; Jarman, M; Jones, A; Lønning, PE; Mehta, A; Powles, T; Stein, R | 1 |
| Coombes, RC; Dowsett, M; Haynes, B; Jarman, M; Jones, A; Lonning, P; MacNeill, F; Mehta, A; Newton, C; Powles, TJ | 1 |
| Dowsett, M; Lønning, PE; Powles, TJ | 1 |
| Dowsett, M | 1 |
| Honjo, H; Inoue, S; Kitawaki, J; Okada, H; Tamura, T; Urabe, M; Yamamoto, T | 1 |
| Goss, PE; Griggs, LJ; Jarman, M; Seago, A | 1 |
| Aboul-Enein, HY; Ogbunude, PO | 1 |
| Etienne, MC; Milano, G; Oster, W | 1 |
| Buzdar, AU; Roseman, BJ; Singletary, SE | 1 |
| Bonneterre, J; Feutrie, ML | 1 |
| Hefnawy, MM | 1 |
4 review(s) available for aminoglutethimide and rogletimide
| Article | Year |
|---|---|
Postmenopausal estrogen synthesis and metabolism: alterations caused by aromatase inhibitors used for the treatment of breast cancer.
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Fadrozole; Female; Humans; Imidazoles; Menopause; Nitriles | 1990 |
Clinical development of aromatase inhibitors for the treatment of breast and prostate cancer.
Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Estrogen Antagonists; Fadrozole; Humans; Imidazoles; Nitriles | 1990 |
Use of aromatase inhibitors in postmenopausal women with advanced breast cancer.
Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles | 1997 |
[Aromatase inhibitors].
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles | 1999 |
1 trial(s) available for aminoglutethimide and rogletimide
| Article | Year |
|---|---|
Endocrine, pharmacokinetic and clinical studies of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione ('pyridoglutethimide') in postmenopausal breast cancer patients.
Topics: Aged; Aminoglutethimide; Antineoplastic Agents; Aromatase Inhibitors; Biological Availability; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Female; Hormones; Humans; Menopause; Middle Aged | 1991 |
14 other study(ies) available for aminoglutethimide and rogletimide
| Article | Year |
|---|---|
Crystallographic and molecular modeling studies on 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione and its butyl analogue, inhibitors of mammalian aromatase. Comparison with natural substrates: prediction of enantioselectivity for N-alkyl derivatives.
Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Chemical Phenomena; Chemistry; Crystallography; Humans; Models, Molecular; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship | 1990 |
Analogues of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents.
Topics: Alkylation; Aminoglutethimide; Antineoplastic Agents; Aromatase Inhibitors; Chromatography, High Pressure Liquid; Mathematics; Structure-Activity Relationship | 1987 |
Analogues of aminoglutethimide: selective inhibition of aromatase.
Topics: Aminoglutethimide; Animals; Aromatase Inhibitors; Humans; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Oxidoreductases; Rats; Testosterone | 1985 |
The influence of aminoglutethimide and its analogue rogletimide on peripheral aromatisation in breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Estrogens; Female; Humans; Hydrocortisone; Middle Aged | 1992 |
Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (rogletimide) and discovery of potent 5-alkyl derivatives.
Topics: Aminoglutethimide; Aromatase Inhibitors; Humans; Molecular Conformation; Structure-Activity Relationship | 1992 |
On-line continuous-flow dialysis thermospray tandem mass spectrometry for quantitative screening of drugs in plasma: rogletimide.
Topics: Aminoglutethimide; Chromatography, Liquid; Dialysis; Humans; Mass Spectrometry | 1992 |
The effect of the aromatase inhibitor, rogletimide (pyridoglutethimide), on guinea pig adrenal cell steroidogenesis and placental microsomal aromatase activity: comparison with aminoglutethimide and CGS 16949A.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Aromatase; Aromatase Inhibitors; Fadrozole; Female; Guinea Pigs; Hydrocortisone; Imidazoles; In Vitro Techniques; Kinetics; Male; Microsomes; Nitriles; Placenta; Pregnancy; Steroids | 1991 |
Characterisation of metabolites of 3-ethyl-3-(4-pyridyl)-piperidine-2,6-dione, a potential breast cancer drug.
Topics: Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Chromatography, High Pressure Liquid; Female; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Reference Standards | 1991 |
Pharmacokinetics and pharmacodynamics of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione in patients with postmenopausal breast cancer.
Topics: Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Estradiol; Estrogens, Conjugated (USP); Estrone; Female; Humans; Middle Aged; Time Factors | 1991 |
Selective aromatase inhibition by pyridoglutethimide, an analogue of aminoglutethimide.
Topics: Aminoglutethimide; Aromatase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Placenta; Steroid Hydroxylases; Tumor Cells, Cultured | 1990 |
Pyridoglutethimide [3-ethyl-3-(4-pyridyl)-piperidine-2,6-dione], an analogue of aminoglutethimide. Metabolism and pharmacokinetics.
Topics: Aminoglutethimide; Animals; Antineoplastic Agents; Chromatography, Thin Layer; Female; Half-Life; Humans; Kinetics; Male; Mass Spectrometry; Rabbits; Rats; Rats, Inbred Strains | 1986 |
In vitro inhibition of aromatase by the enantiomers of aminoglutethimide and analogs.
Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Female; Glutethimide; In Vitro Techniques; Microsomes; Ovary; Rats; Stereoisomerism | 1994 |
Development and validation of a chiral high-performance liquid chromatography assay for rogletimide and rogletimide-N-oxide isomers in plasma.
Topics: Aminoglutethimide; Antineoplastic Agents; Aromatase Inhibitors; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Humans; Oxides; Reproducibility of Results; Stereoisomerism | 1996 |
Stereoselective determination of pyridoglutethimide enantiomers in serum with a chiral cellulose-based high-performance liquid chromatographic column using solid phase extraction and UV detection.
Topics: Aminoglutethimide; Animals; Calibration; Cattle; Cellulose; Chromatography, High Pressure Liquid; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism | 2003 |