aminoglutethimide and mitotane

aminoglutethimide has been researched along with mitotane in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199018 (62.07)18.7374
1990's7 (24.14)18.2507
2000's2 (6.90)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Kishi, DT1
Bricaire, H; Ghnassia, JP; Luton, JP1
Auzeby, A; Bogdan, A; Dommergues, JP; Touitou, Y1
deAsis, DN; Samaan, NA1
Scott, RD1
Bruderman, I; Griffel, WB; Gutman, A; Myers, B; Shapiro, MS1
Garnett, WR; May, CA1
Carey, RM; Hartmann, WH; Orth, DN1
Schein, PS1
Raith, L1
Aida, M; Miura, K1
Plager, JE1
Agostino, A; Altomonte, G; Jacobelli, A1
Elias, AN; Gwinup, G1
Bergstrand, CG; Nilsson, KO1
Krieger, DT1
Bricaire, H; Luton, JP1
Averill, KT; Moore, RN; Penney, DP1
Crapo, L; Miller, JW1
Freeman, DA1
Dluhy, RG; Solomon, CG1
Kasperlik-Załuska, AA; Makowska, AM; Migdalska, BM; Zgliczyński, S1
Engelhardt, D1
Nishikawa, T; Saito, J1
Corley, PA1
Ito, N; Morishita, K; Okumura, H; Takahashi, N1
Leal-Cerro, A; León Justel, A; Mangas, MA; Soto Moreno, A; Webb, S1

Reviews

11 review(s) available for aminoglutethimide and mitotane

ArticleYear
Current therapeutic concepts--Cushing's syndrome.
    Journal of the American Pharmaceutical Association, 1975, Volume: 15, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Circadian Rhythm; Cushing Syndrome; Diagnosis, Differential; Face; Feedback; Humans; Hydrocortisone; Hyperglycemia; Mitotane; Muscular Diseases; Obesity; Paraneoplastic Endocrine Syndromes; Prognosis

1975
Treatment of adrenocortical carcinoma: a case report and review of the literature.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Kinetics; Mitotane; Steroids

1986
Chemotherapeutic management of the hormone-secreting endocrine malignancies.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Antineoplastic; Antineoplastic Agents; Butanones; Carcinoid Tumor; Diazoxide; Humans; Hypoglycemia; Insulin Antagonists; Kidney Tubules; Metyrapone; Mitotane; Neoplasm Metastasis; Pheochromocytoma; Pyrimidines; Pyrroles; Pyrrolidines; Ribonucleosides; Serotonin Antagonists; Streptozocin

1972
[Agents inhibiting steroid biosynthesis--aminoglutethimide and o,p'-DDD].
    Nihon rinsho. Japanese journal of clinical medicine, 1974, Nov-10, Volume: 32, Issue:11

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Animals; Chemical Phenomena; Chemistry; Child; Cushing Syndrome; Dogs; Humans; Hypertension; Mice; Mitochondria; Mitotane; Species Specificity; Thyroid Hormones

1974
Effects of some clinically encountered drugs on steroid synthesis and degradation.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:6

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Drug Interactions; Ethanol; Fetus; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hydroxycholecalciferols; Liver; Metyrapone; Mitotane; Phenobarbital; Phenytoin; Rifampin; Spironolactone; Steroids

1980
Treatment of Cushing's disease in children.
    Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:1

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Child; Cushing Syndrome; Cyproheptadine; Dihydrotestosterone; Female; Humans; Metyrapone; Mitotane; Pituitary Gland; Valproic Acid

1982
Pathophysiology and treatment of Cushing's disease.
    Progress in clinical and biological research, 1982, Volume: 87

    Topics: Adrenal Glands; Adrenalectomy; Aminoglutethimide; Cushing Syndrome; Delayed-Action Preparations; Humans; Hypothalamus; Metyrapone; Mitotane; Pituitary Gland

1982
The medical treatment of Cushing's syndrome.
    Endocrine reviews, 1993, Volume: 14, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Animals; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dogs; Horses; Humans; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Octreotide; Palliative Care; Pituitary Gland; Radiography; Valproic Acid

1993
Steroid biosynthesis inhibitors in Cushing's syndrome.
    The Clinical investigator, 1994, Volume: 72, Issue:7

    Topics: Adrenal Cortex Hormones; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane

1994
[Clinical usefulness of pharmacological treatment of Cushing's syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1994, Volume: 52, Issue:3

    Topics: Administration, Oral; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Humans; Ketoconazole; Metyrapone; Mitotane

1994
[The medical management of Cushing's syndrome].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2009, Volume: 56, Issue:4

    Topics: Adrenal Cortex; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Combined Modality Therapy; Cushing Syndrome; Dopamine Agonists; Glucocorticoids; Humans; Hydrocortisone; Hypophysectomy; Imidazoles; Mitotane; Pituitary Gland, Anterior; Rosiglitazone; Somatostatin; Thiazolidinediones

2009

Other Studies

18 other study(ies) available for aminoglutethimide and mitotane

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[Medical treatment and Cushing's disease].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, Jun-23, Volume: 53, Issue:24

    Topics: Aminoglutethimide; Bromocriptine; Cushing Syndrome; Cyproheptadine; Humans; Mitotane

1977
Glucocorticoid and mineralocorticoid pathways in two adrenocortical carcinomas: comparison of the effects of o,p'-dichlorodiphenyldichloroethane, aminoglutethimide and 2-p-aminophenyl-2-phenylethylamine in vitro.
    The Journal of endocrinology, 1979, Volume: 82, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adult; Aminoglutethimide; Aniline Compounds; Child; Cortodoxone; Desoxycorticosterone; Female; Glucocorticoids; Humans; In Vitro Techniques; Male; Mineralocorticoids; Mitotane; Phenethylamines; Steroid Hydroxylases

1979
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism.
    Archives of internal medicine, 1978, Volume: 138, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Androstenedione; Cushing Syndrome; Dexamethasone; Estrogens; Feminization; Humans; Hyperparathyroidism; Male; Metyrapone; Mitotane; Paraneoplastic Endocrine Syndromes; Parathyroid Hormone; Testosterone

1978
Treatment of an adrenal cortical carcinoma with a combination of o,p'-DDD and aminoglutethimide.
    Postgraduate medical journal, 1975, Volume: 51, Issue:591

    Topics: 11-Hydroxycorticosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aminoglutethimide; Cushing Syndrome; Dexamethasone; Drug Combinations; Humans; Hydrocortisone; Lymphatic Metastasis; Male; Mitotane; Nephrectomy; Steroids

1975
Cushing's syndrome associated with a bronchial adenoma. Possible periodic hormonogenesis.
    Israel journal of medical sciences, 1975, Volume: 11, Issue:9

    Topics: Adenoma; Adrenalectomy; Adult; Aminoglutethimide; Bronchial Neoplasms; Cushing Syndrome; Dexamethasone; Humans; Male; Mitotane; Paraneoplastic Endocrine Syndromes

1975
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Female; Hormones, Ectopic; Humans; Hydrocortisone; Melanoma; Metyrapone; Middle Aged; Mitotane; Neoplasm Metastasis; Palliative Care

1973
[Medical therapy of hyperadrenalism].
    Minerva medica, 1973, Mar-14, Volume: 64, Issue:14

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Humans; Metyrapone; Mitotane

1973
Carcinoma of the adrenal cortex: clinical description, diagnosis, and treatment.
    International advances in surgical oncology, 1984, Volume: 7

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Antineoplastic Agents; Combined Modality Therapy; Diagnosis, Differential; Humans; Metyrapone; Mitotane; Prognosis; Radiotherapy Dosage

1984
[Treatment of glycoactive hypercorticism].
    La Clinica terapeutica, 1984, Nov-30, Volume: 111, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Combined Modality Therapy; Cushing Syndrome; Drug Therapy, Combination; Humans; Hypophysectomy; Mitotane; Pituitary Irradiation

1984
[Cushing's syndrome. Medical treatment of adrenal hypercorticism].
    Hormone research, 1980, Volume: 13, Issue:4-5

    Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Androstanols; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dihydrotestosterone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Metyrapone; Mitotane; Nitriles

1980
Fine structural and biochemical effects of aminoglutethimide and o,p'-DDD on rat adrenocortical carcinoma 494 and adrenals.
    The Anatomical record, 1980, Volume: 198, Issue:1

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aminoglutethimide; Animals; Cholesterol; Corticosterone; Male; Mitochondria; Mitotane; Neoplasms, Experimental; Rats

1980
Adrenal carcinoma.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Diagnosis, Differential; Humans; Metyrapone; Mitotane; Neoplasm Metastasis

1994
Paraneoplastic endocrine syndromes.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Acromegaly; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Calcitonin; Cushing Syndrome; Diazoxide; Diphosphonates; Estrogens; Fluid Therapy; Hemangiopericytoma; Humans; Hypercalcemia; Hyperthyroidism; Hypoglycemia; Inappropriate ADH Syndrome; Ketoconazole; Mifepristone; Mineralocorticoids; Mitotane; Octreotide; Osteomalacia; Pamidronate; Paraneoplastic Endocrine Syndromes; Phosphorus; Plicamycin; Propylthiouracil; Saline Solution, Hypertonic; Somatostatin; Thyroid Neoplasms

1994
Adrenocortical carcinoma. A clinical study and treatment results of 52 patients.
    Cancer, 1995, May-15, Volume: 75, Issue:10

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adrenocortical Hyperfunction; Adult; Aged; Aminoglutethimide; Chemotherapy, Adjuvant; Cushing Syndrome; Female; Follow-Up Studies; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hydrocortisone; Male; Middle Aged; Mitotane; Neoplasm Staging; Survival Rate; Testosterone; Treatment Outcome

1995
Acquired immune deficiency syndrome: the glucocorticoid solution.
    Medical hypotheses, 1996, Volume: 47, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adrenocorticotropic Hormone; Aminoglutethimide; CD8-Positive T-Lymphocytes; Corticotropin-Releasing Hormone; Glucocorticoids; HIV; HIV Envelope Protein gp120; Humans; Hydrocortisone; Interleukin-1; Lymphocyte Activation; Metyrapone; Mitotane; Models, Biological; Receptors, Pituitary Hormone; T-Lymphocytes

1996
Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis.
    Toxicology, 2001, Aug-28, Volume: 165, Issue:2-3

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aminoglutethimide; Animals; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Dogs; Female; Ketoconazole; Metyrapone; Miconazole; Mitotane; Toxicity Tests

2001