aminoglutethimide and metyrapone

aminoglutethimide has been researched along with metyrapone in 113 studies

Research

Studies (113)

Timeframe	Studies, this research(%)	All Research%
pre-1990	74 (65.49)	18.7374
1990's	22 (19.47)	18.2507
2000's	14 (12.39)	29.6817
2010's	2 (1.77)	24.3611
2020's	1 (0.88)	2.80

Authors

Authors	Studies
Berger, ML; Hahner, S; Hammerschmidt, F; Peric-Simov, B; Schirbel, A; Zolle, IM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Beinhert, H; Jefcoate, CR; Orme-Johnson, WH	1
Simpson, ER; Williams-Smith, DL	1
Cammack, R; Williams-Smith, DL	1
Beierwaltes, WH; Gill, SP; Ice, RD; Mosley, ST; Sarkar, SD; Seabold, JE; Wieland, DM	1
Burke, CW; Burley, DM; Child, DF; Fraser, TR; Rees, LH	1
Dupont, W; Leboulenger, F; Vaillant, R; Vaudry, H	1
Levine, LS; New, MI; Peterson, RE; Saenger, P	1
Benaim, M; Cook, D; Evered, DC; Hall, R; Hunter, P; Ross, WM	1
Critselis, AN; Levenson, SM; Rettura, G; Seifter, E	1
Koelmeyer, TD; Woods, WP	1
Hollifield, JW; Island, DP; Liddle, GW; Sennett, JA; Slaton, PE; Wilson, HM; Yarbro, L	1
Clifton-Bligh, P; McElduff, A; Posen, S	1
Lanthier, A; Patwardhan, VV	1
deAsis, DN; Samaan, NA	1
Beyer, C; Larsson, K; Moralí, G; Naftolin, F	1
Rothschild, AJ; Schatzberg, AF	1
Chouinard, G; Dhar, V; Ghadirian, AM; Keller, R; Murphy, BE	1
Murphy, BE	1
Allolio, B; Jaursch-Hancke, C; Kaulen, D; Reincke, M; Winkelmann, W	1
Rawashdeh, N; Ray, D; Rose, JC; Turner, CS	1
Plotsky, PM; Sawchenko, PE	1
Darbeida, H; Durand, P; Naaman, E	1
Numazawa, M; Satoh, S	1
Kairaluoma, M; Pasanen, M; Pelkonen, O; Sotaniemi, EA; Taskinen, T	1
Adamson, U; Sjöberg, HE; Thorén, M	1
Colby, HD; Eacho, PI	1
Carey, RM; Hartmann, WH; Orth, DN	1
Gillette, PN; Kappas, A; Rifkind, AB; Song, CS	1
Müller, J	1
DeLuca, HF; Ghazarian, JG; Jefcoate, CR; Knutson, JC; Orme-Johnson, WH	1
Davis, TK; Sloane, NH	1
Gaunt, R; Gisoldi, E; Herkner, J; Howie, N; Renzi, AA	1
Liddle, GW; Temple, TE	1
Earll, JM; Forsham, PH; Smilo, RP	1
Brough, AJ; Cash, R; Petrini, MA	1
Bates, RW; Garrison, MM	1
Brun, J; Queneau, P; Revol, A	1
Liddle, GW; Orth, DN	1
Melby, JC	1
Bartová, A; Birmingham, MK; Tibagong, M	1
Gregorová, I; Horký, K; Kuchel, O; Stárka, L	1
Callard, IP; Daugherty, DR	1
Malendowicz, LK	2
Schein, PS	1
Raith, L	2
Birkhimer, ML; Parkes, DG; Sherwood, OD	1
Belchetz, PE; Bloom, SR; Brown, CL; Makin, HL; Mason, AS; Ratcliffe, JG; Trafford, DJ	1
Parvez, H; Parvez, S	1
Siiteri, PK; Thompson, EA	1
Caselitz, J; Saeger, W	1
Cook, DB; Hall, R; Hunter, PR; Ross, W	1
Gower, DB	1
Carballeira, A; Durnhofer, F; Fishman, LM	1
Jeffries, CD; Wilkins, J	1
Harding, BW; Wilson, LD	1
Daniels, VG; Hardy, RN; Malinowska, KW	1
Siegenthaler, W; Werning, C	1
Bernard, EA; Wassermann, GF	1
McIntosh, EN; Salhanick, HA	1
Plager, JE	1
Findling, JW; Gogel, EL; Rosenblum, ML; Salber, PR; Tyrrell, JB	1
Kinouchi, T; Shimizu, N	1
Huston, TM; Tojo, H	1
Kimura, T; Klimek, J; Schaap, AP	1
Lehoux, JG; Preiss, B	1
Elias, AN; Gwinup, G	1
Morris, B; Morris, R	1
Bergstrand, CG; Nilsson, KO	1
Akana, SF; Dallman, MF; Shinsako, J	1
Margolis, S; Schwartz, MA	1
Krieger, DT	1
Curtis, JC; Marsaw, B; Mathew, JK; Mrotek, JJ	1
Bricaire, H; Luton, JP	1
Delarue, C; Jegou, S; Leboulenger, F; Leroux, P; Netchitailo, P; Tonon, MC; Vaudry, H	1
Darbeida, H; Durand, P; Picard-Hagen, N	1
Crapo, L; Miller, JW	1
Freeman, DA	1
Auzéby, A; Bogdan, A; Touitou, Y	1
Chouinard, G; Dhar, V; Engelsmann, F; Filipini, D; Ghadirian, AM; Keller, R; Murphy, BE	1
Miura, K	1
Engelhardt, D	1
Engelhardt, D; Weber, MM	1
Nishikawa, T; Saito, J	1
Khalil, MW; Killinger, DW; Strutt, B; Vachon, D	1
Jefcoate, CR; McNamara, BC; Yamazaki, T	1
Levine, BS; Matamoros, RA	1
Corley, PA	1
Abrahamsen, GC; Carr, KD	1
Boyle, T; Dukes, M; Edwards, PN; Large, M; Smith, IK	1
Loscertales, M; Rose, SP; Sandi, C	1
Dhar, V; Ghadirian, AM; Murphy, BE	1
Allolio, B; Beuschlein, F; Fassnacht, M; Mora, P; Reincke, M; Vay, S	1
Comi, RJ; Gorden, P	1
Douglas, AJ; Johnstone, HA; Landgraf, R; Neumann, ID; Russell, JA; Seckl, JR; Wigger, A	1
Boyd, RL; Cole, TJ; Godfrey, DI; Purton, JF	1
Allolio, B; Beuschlein, F; Fassnacht, M; Hahner, S; Klink, A; Reincke, M	1
Ito, N; Morishita, K; Okumura, H; Takahashi, N	1
Anguiano, B; Valverde, C	1
Johansson, MK; Lund, BO; Sanderson, JT	1
Bland, ST; Deak, T; Der-Avakian, A; Maier, SF; Nguyen, KT; Schmid, MJ; Spencer, RL; Watkins, LR; Will, MJ	1
Giesy, JP; Gracia, T; Hecker, M; Higley, EB; Hilscherova, K; Jones, PD; Newsted, JL; Sanderson, JT; Wu, RS; Yu, RM; Zhang, X	1
Nishikawa, T; Omura, M; Saito, J	1
Gillis, D; Hannon, TS; Hirsch, HJ; Koplewitz, BZ; Rösler, A	1
Coleman, VH; Kling, MA; Schulkin, J	1
Forest, M; Nicolino, M; Vong, CH	1
Behuliak, M; Bencze, M; Vavřínová, A; Zicha, J	1

Reviews

18 review(s) available for aminoglutethimide and metyrapone

Article	Year
Inhibitors of adrenal steroid biosynthesis. Annual review of pharmacology, 1970, Volume: 10 Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Animals; Dichlorodiphenyldichloroethane; Dogs; Heparin; Heparinoids; Humans; Hydrocortisone; Hypertension; Metyrapone; Phenethylamines; Pituitary-Adrenal System; Pyridines; Sodium; Stress, Physiological	1970
Chemotherapeutic management of the hormone-secreting endocrine malignancies. Cancer, 1972, Volume: 30, Issue:6 Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Antineoplastic; Antineoplastic Agents; Butanones; Carcinoid Tumor; Diazoxide; Humans; Hypoglycemia; Insulin Antagonists; Kidney Tubules; Metyrapone; Mitotane; Neoplasm Metastasis; Pheochromocytoma; Pyrimidines; Pyrroles; Pyrrolidines; Ribonucleosides; Serotonin Antagonists; Streptozocin	1972
Modifiers of steroid-hormone metabolism: a review of their chemistry, biochemistry and clinical applications. Journal of steroid biochemistry, 1974, Volume: 5, Issue:5 Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aminoglutethimide; Androgens; Androstenedione; Animals; Cholesterol; Dexamethasone; Estrogens; Estrone; Glutethimide; Hormones; Humans; Hydrocortisone; Methane; Metyrapone; Microscopy, Electron; Pharmacology; Phenols; Pregnenolone; Pyridines; Steroid Hydroxylases; Steroids; Time Factors	1974
Adrenal function and macromolecular transport across rat intestine. Nutrition reviews, 1974, Volume: 32, Issue:6 Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Age Factors; Aminoglutethimide; Animals; Animals, Newborn; Corticosterone; Cortisone; Female; Immunoglobulins; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Intubation, Gastrointestinal; Macromolecular Substances; Metyrapone; Permeability; Povidone	1974
[Pharmacological mechanism of modern diuretics. Aldosterone antagonists]. Nihon rinsho. Japanese journal of clinical medicine, 1984, Volume: 42, Issue:9 Topics: Aldosterone; Aminoglutethimide; Angiotensin-Converting Enzyme Inhibitors; Diuretics; Humans; Kidney Tubules, Distal; Metyrapone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone	1984
Effects of some clinically encountered drugs on steroid synthesis and degradation. Metabolism: clinical and experimental, 1980, Volume: 29, Issue:6 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Drug Interactions; Ethanol; Fetus; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hydroxycholecalciferols; Liver; Metyrapone; Mitotane; Phenobarbital; Phenytoin; Rifampin; Spironolactone; Steroids	1980
Treatment of Cushing's disease in children. Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:1 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Child; Cushing Syndrome; Cyproheptadine; Dihydrotestosterone; Female; Humans; Metyrapone; Mitotane; Pituitary Gland; Valproic Acid	1982
Pathophysiology and treatment of Cushing's disease. Progress in clinical and biological research, 1982, Volume: 87 Topics: Adrenal Glands; Adrenalectomy; Aminoglutethimide; Cushing Syndrome; Delayed-Action Preparations; Humans; Hypothalamus; Metyrapone; Mitotane; Pituitary Gland	1982
The medical treatment of Cushing's syndrome. Endocrine reviews, 1993, Volume: 14, Issue:4 Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Animals; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dogs; Horses; Humans; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Octreotide; Palliative Care; Pituitary Gland; Radiography; Valproic Acid	1993
[Non-invasive therapy of Cushing's syndrome]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1994, Sep-10, Volume: 83, Issue:9 Topics: Aminoglutethimide; Betamethasone; Bromocriptine; Clinical Trials as Topic; Cushing Syndrome; Cyproheptadine; Follow-Up Studies; Humans; Metyrapone	1994
Steroid biosynthesis inhibitors in Cushing's syndrome. The Clinical investigator, 1994, Volume: 72, Issue:7 Topics: Adrenal Cortex Hormones; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane	1994
Therapy of Cushing's syndrome with steroid biosynthesis inhibitors. The Journal of steroid biochemistry and molecular biology, 1994, Volume: 49, Issue:4-6 Topics: 3-Hydroxysteroid Dehydrogenases; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate; Humans; Ketoconazole; Metyrapone; Steroids	1994
[Clinical usefulness of pharmacological treatment of Cushing's syndrome]. Nihon rinsho. Japanese journal of clinical medicine, 1994, Volume: 52, Issue:3 Topics: Administration, Oral; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Humans; Ketoconazole; Metyrapone; Mitotane	1994
Long-term medical treatment of ectopic ACTH syndrome. Southern medical journal, 1998, Volume: 91, Issue:11 Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenocortical Hyperfunction; Aminoglutethimide; Antineoplastic Agents, Hormonal; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Metyrapone; Middle Aged; Recurrence	1998
Stress-free T-cell development: glucocorticoids are not obligatory. Immunology today, 2000, Volume: 21, Issue:12 Topics: Aminoglutethimide; Animals; Cell Differentiation; Clonal Deletion; DNA, Antisense; Glucocorticoids; Hematopoiesis; Hormone Antagonists; Humans; Immunologic Deficiency Syndromes; Lymphocyte Activation; Metyrapone; Mice; Mice, Knockout; Mice, Transgenic; Mifepristone; Models, Biological; Receptors, Glucocorticoid; Stress, Physiological; T-Lymphocyte Subsets; Thymus Gland	2000
New mechanisms of adrenostatic compounds in a human adrenocortical cancer cell line. European journal of clinical investigation, 2000, Volume: 30 Suppl 3 Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Cell Division; Cholesterol Side-Chain Cleavage Enzyme; Etomidate; Humans; Hydrocortisone; Metyrapone; Receptors, Corticotropin; Receptors, Glucocorticoid; RNA, Messenger; Steroids; Tumor Cells, Cultured	2000
[Medical treatment for Cushing's syndrome]. Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:1 Topics: Aminoglutethimide; Aromatase Inhibitors; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Steroid 11-beta-Hydroxylase	2008
Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus? Depression and anxiety, 2009, Volume: 26, Issue:7 Topics: Adrenal Glands; Aminoglutethimide; Anti-Inflammatory Agents; Corticotropin-Releasing Hormone; Depressive Disorder, Major; Double-Blind Method; Glucocorticoids; Humans; Hydrocortisone; Hypothalamus; Ketoconazole; Metyrapone; Mifepristone; Severity of Illness Index	2009

Trials

6 trial(s) available for aminoglutethimide and metyrapone

Article	Year
Are there unknown mineralocorticoids in low-renin essential hypertension? Mayo Clinic proceedings, 1977, Volume: 52, Issue:5 Topics: Aminoglutethimide; Blood Pressure; Clinical Trials as Topic; Humans; Hyperaldosteronism; Hypertension; Metyrapone; Mineralocorticoids; Posture; Renin	1977
Response to steroid suppression in major depression resistant to antidepressant therapy. Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:2 Topics: Adult; Aminoglutethimide; Antidepressive Agents; Dehydroepiandrosterone; Depressive Disorder; Dexamethasone; Dose-Response Relationship, Drug; Female; Hospitalization; Humans; Hydrocortisone; Ketoconazole; Male; Metyrapone; Middle Aged; Psychiatric Status Rating Scales	1991
Treatment of major depression with steroid suppressive drugs. The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:2 Topics: Adrenocortical Hyperfunction; Adult; Aged; Aminoglutethimide; Cushing Syndrome; Depressive Disorder; Female; Humans; Male; Metyrapone	1991
Aminoglutethimide and metyrapone in the management of Cushing's syndrome. Acta endocrinologica, 1985, Volume: 109, Issue:4 Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Clinical Trials as Topic; Cushing Syndrome; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Male; Metyrapone; Middle Aged; Retrospective Studies	1985
Effect of aminoglutethimide on urinary steroid excretion in patients with congenital adrenal hyperplasia due to incomplete 21-hydroxylase deficiency. Metabolism: clinical and experimental, 1972, Volume: 21, Issue:4 Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Androsterone; Aniline Compounds; Anticonvulsants; Chemistry, Clinical; Clinical Trials as Topic; Dehydroepiandrosterone; Depression, Chemical; Dexamethasone; Etiocholanolone; Female; Humans; Metabolism, Inborn Errors; Metyrapone; Mixed Function Oxygenases; Pregnanetriol; Pyridones	1972
Neuroendocrine responses to inhibitors of steroid biosynthesis in patients with major depression resistant to antidepressant therapy. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:3 Topics: Adult; Aminoglutethimide; Analysis of Variance; Androgen Antagonists; Antidepressive Agents; Dehydroepiandrosterone Sulfate; Depressive Disorder; Dexamethasone; Drug Resistance; Enzyme Inhibitors; Female; Hormone Antagonists; Humans; Hydrocortisone; Ketoconazole; Male; Metyrapone; Middle Aged; Steroids; Treatment Outcome	1998

Other Studies

89 other study(ies) available for aminoglutethimide and metyrapone

Article	Year
New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Adrenal Cortex; Animals; Binding Sites; Etomidate; Humans; Hydroxylation; Iodine Radioisotopes; Kinetics; Male; Molecular Structure; Rats; Rats, Wistar; Stereoisomerism; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Cytochrome P-450 of bovine adrenal mitochondria. Ligand binding to two forms resolved by EPR spectroscopy. The Journal of biological chemistry, 1976, Jun-25, Volume: 251, Issue:12 Topics: Adrenal Cortex; Adrenal Glands; Aminoglutethimide; Animals; Binding Sites; Cattle; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Ligands; Metyrapone; Mitochondria; Protein Binding; Protein Conformation; Steroids	1976
Electron paramagnetic resonance spectra of mitochondrial and microsomal cytochrome P-450 from the rat adrenal. Biochimica et biophysica acta, 1976, Oct-13, Volume: 449, Issue:1 Topics: Adrenal Glands; Aminoglutethimide; Animals; Calcium; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Female; Hydrogen-Ion Concentration; Isocitrates; Metyrapone; Microsomes; Mitochondria; Pregnenolone; Rats; Succinates	1976
Oxidation-reduction potentials of cytochromes P-450 and ferredoxin in the bovine adrenal. Their modification by substrates and inhibitors. Biochimica et biophysica acta, 1977, Oct-25, Volume: 499, Issue:3 Topics: Adrenal Glands; Aminoglutethimide; Animals; Cattle; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Ferredoxins; Hydrogen-Ion Concentration; Hydroxycholesterols; Metyrapone; Microsomes; Mitochondria; Oxidation-Reduction; Potentiometry; Protein Binding	1977
Localization of radiolabeled enzyme inhibitors in the adrenal gland. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1976, Volume: 17, Issue:11 Topics: Adrenal Gland Diseases; Adrenal Glands; Aminoglutethimide; Aniline Compounds; Animals; Butanones; Dogs; Enzyme Inhibitors; Female; Iodine Radioisotopes; Metyrapone; Naphthalenes; Phenethylamines; Pyridines; Radionuclide Imaging; Rats; Tetrahydronaphthalenes; Tritium	1976
Drug controlled of Cushing's syndrome. Combined aminoglutethimide and metyrapone therapy. Acta endocrinologica, 1976, Volume: 82, Issue:2 Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Dexamethasone; Drug Evaluation; Drug Therapy, Combination; Female; Fludrocortisone; Humans; Hydrocortisone; Male; Metyrapone; Time Factors	1976
Regulation of the aldosterone secretion in the frog Rana esculenta L. General and comparative endocrinology, 1976, Volume: 29, Issue:1 Topics: Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Blood Pressure; Corticosterone; Female; Hypophysectomy; Kidney; Male; Metyrapone; Pituitary Gland; Rana esculenta	1976
Evidence for an unidentified ACTH-induced steroid hormone causing hypertension. The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:6 Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone; Aminoglutethimide; Dexamethasone; Diuresis; Drug Interactions; Hormones; Humans; Hyperaldosteronism; Hypertension; Male; Metyrapone; Renin; Steroids	1976
Treatment of Cushing's disease with adrenal blocking drugs and megavoltage therapy to the pituitary. Clinical radiology, 1979, Volume: 30, Issue:2 Topics: Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Aminoglutethimide; Cushing Syndrome; Female; Humans; Hydrocortisone; Male; Metyrapone; Middle Aged; Pituitary Irradiation; Radiotherapy, High-Energy; Time Factors	1979
Effect of metyrapone and aminoglutethimide on the murine sarcoma (MuSV-M) and breast adenocarcinoma (C3HBA). Journal of surgical oncology, 1979, Volume: 12, Issue:3 Topics: Adenocarcinoma; Aminoglutethimide; Animals; Female; Male; Mammary Neoplasms, Experimental; Metyrapone; Rats; Sarcoma Viruses, Murine; Sarcoma, Experimental	1979
Carcinoma of the lung presenting as Cushing's syndrome. The New Zealand medical journal, 1977, Jan-12, Volume: 85, Issue:579 Topics: Aminoglutethimide; Carcinoma, Bronchogenic; Cortisone; Cushing Syndrome; Cyclophosphamide; Diagnosis, Differential; Female; Humans; Lung Neoplasms; Metyrapone; Middle Aged; Spironolactone	1977
Metastatic medullary carcinoma of the thyroid complicated by Cushing's syndrome. The Medical journal of Australia, 1979, Mar-10, Volume: 1, Issue:5 Topics: Adult; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dexamethasone; Drug Therapy, Combination; Humans; Male; Metyrapone; Neoplasm Metastasis; Thyroid Neoplasms	1979
Effects of inhibitors of steroid biosynthesis on prostaglandin formation in rabbit ovarian follicles. Prostaglandins, 1979, Volume: 18, Issue:6 Topics: Aminoglutethimide; Androstenols; Animals; Estradiol; Female; Luteinizing Hormone; Metyrapone; Ovarian Follicle; Pregnenolone; Progesterone; Prostaglandins E; Prostaglandins F; Rabbits; Spiro Compounds; Testosterone	1979
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism. Archives of internal medicine, 1978, Volume: 138, Issue:2 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Androstenedione; Cushing Syndrome; Dexamethasone; Estrogens; Feminization; Humans; Hyperparathyroidism; Male; Metyrapone; Mitotane; Paraneoplastic Endocrine Syndromes; Parathyroid Hormone; Testosterone	1978
Effect of some antiestrogens and aromatase inhibitors on androgen induced sexual behavior in castrated male rats. Hormones and behavior, 1976, Volume: 7, Issue:3 Topics: Aminoglutethimide; Androstenedione; Animals; Castration; Clomiphene; Drug Interactions; Ejaculation; Ethamoxytriphetol; Male; Metyrapone; Rats; Sexual Behavior, Animal; Tamoxifen; Testosterone; Time Factors	1976
Theoretical basis for response to steroid suppression in major depression. Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:2 Topics: Aminoglutethimide; Depressive Disorder; Dopamine; Humans; Hydrocortisone; Ketoconazole; Metyrapone	1992
[Adrenostatic treatment of ACTH-dependent Cushing syndrome using metyrapone and aminoglutethimide]. Deutsche medizinische Wochenschrift (1946), 1987, Oct-02, Volume: 112, Issue:40 Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aminoglutethimide; Cushing Syndrome; Female; Humans; Hydrocortisone; Male; Metyrapone; Middle Aged	1987
Evidence that cortisol inhibits basal adrenocorticotropin secretion in the sheep fetus by 0.70 gestation. Endocrinology, 1988, Volume: 123, Issue:3 Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Carbon Dioxide; Female; Fetal Blood; Fetus; Gestational Age; Hydrocortisone; Metyrapone; Oxygen; Partial Pressure; Pregnancy; Reference Values; Sheep	1988
Hypophysial-portal plasma levels, median eminence content, and immunohistochemical staining of corticotropin-releasing factor, arginine vasopressin, and oxytocin after pharmacological adrenalectomy. Endocrinology, 1987, Volume: 120, Issue:4 Topics: Adrenal Cortex Hormones; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Arginine Vasopressin; Corticotropin-Releasing Hormone; Fluorescent Antibody Technique; Histocytochemistry; Male; Median Eminence; Metyrapone; Oxytocin; Pituitary Gland; Portal System; Rats; Rats, Inbred Strains	1987
Glucocorticoid induction of the maturation of ovine fetal adrenocortical cells. Biochemical and biophysical research communications, 1987, Jun-30, Volume: 145, Issue:3 Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Bucladesine; Cells, Cultured; Colforsin; Cosyntropin; Cyclic AMP; Fetus; Kinetics; Metyrapone; Sheep	1987
Kinetic studies of inhibition of estradiol 2- and 16 alpha-hydroxylases in rat liver microsomes with various cytochrome P-450 inhibitors. Journal of steroid biochemistry, 1988, Volume: 29, Issue:2 Topics: Aminoglutethimide; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P450 Family 2; Hydroxylation; Kinetics; Male; Metyrapone; Microsomes, Liver; Proadifen; Rats; Rats, Inbred Strains; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases	1988
Inhibitor panel studies of human hepatic and placental cytochrome P-450-associated monooxygenase activities. Pharmacology & toxicology, 1988, Volume: 62, Issue:5 Topics: Aminoglutethimide; Animals; Benzoflavones; Cimetidine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Debrisoquin; Enzyme Inhibitors; Female; Furans; Humans; Isoenzymes; Liver; Male; Metyrapone; Oxidoreductases; Placenta; Pregnancy; Rats; Rats, Inbred Strains	1988
Mitochondrial steroid metabolism in the inner and outer zones of the guinea-pig adrenal cortex. Journal of steroid biochemistry, 1985, Volume: 23, Issue:4 Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aminoglutethimide; Animals; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Guinea Pigs; In Vitro Techniques; Male; Metyrapone; Mitochondria; Pregnenolone	1985
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis. The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:3 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Female; Hormones, Ectopic; Humans; Hydrocortisone; Melanoma; Metyrapone; Middle Aged; Mitotane; Neoplasm Metastasis; Palliative Care	1973
Drug stimulation of -aminolevulinic acid synthetase and cytochrome P-450 in vivo in chick embryo liver. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:2 Topics: 5-Aminolevulinate Synthetase; Age Factors; Aminoglutethimide; Aminopyrine N-Demethylase; Animals; Anticonvulsants; Central Nervous System Stimulants; Chick Embryo; Cycloheximide; Cytochrome P-450 Enzyme System; Dichlorodiphenyldichloroethane; Dose-Response Relationship, Drug; Enzyme Induction; Hypnotics and Sedatives; Liver; Metyrapone; Proadifen; Stimulation, Chemical; Time Factors; Tranquilizing Agents	1973
Regulation of aldosterone biosynthesis. Monographs on endocrinology, 1971, Volume: 5 Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Cations, Divalent; Cations, Monovalent; Central Nervous System; Cyclic AMP; Heparin; Humans; Hypertension, Renal; Hypophysectomy; Hypopituitarism; Metyrapone; NADP; Nephrectomy; Ouabain; Potassium; Progestins; Serotonin; Sodium	1971
Mitochondrial cytochrome p450. A component of chick kidney 25-hydrocholecalciferol-1alpha-hydroxylase. The Journal of biological chemistry, 1974, May-25, Volume: 249, Issue:10 Topics: Adrenal Glands; Aminoglutethimide; Animals; Antimycin A; Binding, Competitive; Carbon Monoxide; Cattle; Chickens; Cytochrome P-450 Enzyme System; Electron Transport Complex IV; Ferredoxins; Hydroxycholecalciferols; Kidney; Kinetics; Male; Metyrapone; Microsomes; Mitochondria; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Spectrophotometry; Steroid Hydroxylases; Tritium	1974
Hydroxymethylation of the benzene ring. Microsomal hydroxymethylation of benzo(alpha)pyrene to 6-hydroxymethylbenzo(alpha)pyrene. Archives of biochemistry and biophysics, 1974, Volume: 163, Issue:1 Topics: Aminoglutethimide; Animals; Benzopyrenes; Butanones; Carbon Monoxide; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Drug Stability; Female; Imidazoles; Methanol; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Temperature; Time Factors; Transferases; Tritium; Ultrasonics	1974
Sodium retention after adrenal enucleation: drug and salt appetite studies. Endocrinology, 1968, Volume: 83, Issue:5 Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Aminoglutethimide; Animals; Appetite; Body Weight; Depression, Chemical; Diuretics; Drinking; Heparinoids; Hydrochlorothiazide; Male; Methandrostenolone; Metyrapone; Mineralocorticoid Receptor Antagonists; Natriuresis; Potassium; Rats; Regeneration; Sodium; Sodium Chloride; Spironolactone; Water-Electrolyte Balance	1968
Suppression of tumorous adrenal hyperfunction by aminoglutethimide. Metabolism: clinical and experimental, 1967, Volume: 16, Issue:4 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Animals; Anticoagulants; Carcinoma; Cushing Syndrome; Female; Humans; Hydrocortisone; Metyrapone; Middle Aged; Pituitary-Adrenal Function Tests; Secretory Rate	1967
Ovarian dysfunction associated with an anticonvulsant drug. JAMA, 1969, May-19, Volume: 208, Issue:7 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Endocrine System Diseases; Female; Humans; Hypertrophy; Metyrapone; Ovary; Pituitary-Adrenal Function Tests; Pyridones; Thyroid Function Tests; Thyroid Gland; Virilism	1969
Delay of hormonally induced diabetes by amino-glutethimide and metyrapone in partially pancreatectomized rats bearing transplantable pituitary tumors. Concomitant failure to prevent splanchnomegaly. Endocrinology, 1970, Volume: 86, Issue:1 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Corticosterone; Diabetes Mellitus; Estradiol; Glycosuria; Growth Hormone; Heart; Insulin; Islets of Langerhans; Kidney; Liver; Metyrapone; Neoplasm Transplantation; Organ Size; Pituitary Neoplasms; Prolactin; Pyridones; Rats; Thymus Gland	1970
[Broncho-pulmonary cancer with true or degraded hypercorticism]. La Presse medicale, 1969, Nov-29, Volume: 77, Issue:51 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Bronchial Neoplasms; Cushing Syndrome; Glucocorticoids; Humans; Hyperpituitarism; Lung Neoplasms; Metyrapone	1969
Results of treatment in 108 patients with Cushing's syndrome. The New England journal of medicine, 1971, Jul-29, Volume: 285, Issue:5 Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Aged; Aminoglutethimide; Carcinoma; Child; Child, Preschool; Cushing Syndrome; Dichlorodiphenyldichloroethane; Female; Hormones, Ectopic; Humans; Hydrocortisone; Hypophysectomy; Infant; Male; Metyrapone; Middle Aged; Pituitary Irradiation; Remission, Spontaneous	1971
Therapeutic possibilities in Cushing's syndrome. The New England journal of medicine, 1971, Jul-29, Volume: 285, Issue:5 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Hormones, Ectopic; Humans; Hydrocortisone; Metyrapone; Pituitary Irradiation; Remission, Spontaneous	1971
Steroid-mediated stimulation of aerobic glycolysis by intact mouse adrenal glands in vitro. Endocrinology, 1971, Volume: 89, Issue:5 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aerobiosis; Aminoglutethimide; Analysis of Variance; Animals; Carbon Isotopes; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Fluorescence; Glycolysis; Hydroxyprogesterones; In Vitro Techniques; Lactates; Male; Metyrapone; Mice; Pregnanes; Progesterone; Pyruvates; Spectrophotometry; Ultraviolet Rays	1971
Plasma corticosterone levels in the male iguanid lizard Sceloporus cyanogenys under various physiological conditions. General and comparative endocrinology, 1972, Volume: 19, Issue:1 Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Body Weight; Chromatography, Thin Layer; Corticosterone; Hydroxysteroid Dehydrogenases; Hypophysectomy; Hypothalamus; Ketones; Lizards; Male; Metyrapone; Organ Size; Protein Binding; Seasons; Stereotaxic Techniques; Testis; Tritium	1972
Comparative studies on the effects of aminoglutethimide, metopirone, ACTH and hydrocortisone on the adrenal cortex of adult male rats. I. Karyometric studies. Virchows Archiv. B, Cell pathology, 1972, Volume: 11, Issue:1 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Cell Nucleus; Corticosterone; Hydrocortisone; Hypertrophy; Karyometry; Male; Metyrapone; Organ Size; Pyridones; Rats	1972
Comparative studies on the effects of aminoglutethimide, metopirone, ACTH and hydrocortisone on the adrenal cortex of adult male rats. II. Histological and histochemical studies. Endokrinologie, 1973, Volume: 61, Issue:1 Topics: Acid Phosphatase; Adenosine Triphosphatases; Adrenal Glands; Adrenocorticotropic Hormone; Alkaline Phosphatase; Aminoglutethimide; Animals; Atrophy; Esterases; Histocytochemistry; Hydrocortisone; Hypertrophy; Lipids; Male; Metyrapone; Nucleotidases; Rats; Succinate Dehydrogenase	1973
[Medical therapy of hyperadrenalism]. Minerva medica, 1973, Mar-14, Volume: 64, Issue:14 Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Humans; Metyrapone; Mitotane	1973
The gonadotropin-primed rat: a model for testing agents that influence steroid biosynthesis. Endocrinology, 1973, Volume: 93, Issue:3 Topics: Adrenal Glands; Aminoglutethimide; Animals; Binding, Competitive; Castration; Chorionic Gonadotropin; Ergot Alkaloids; Estrogens, Conjugated (USP); Female; Luteinizing Hormone; Metyrapone; Organ Size; Ovary; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Progesterone; Prostaglandins; Radioimmunoassay; Rats	1973
ACTH, glucagon and gastrin production by a pancreatic islet cell carcinoma and its treatment. Clinical endocrinology, 1973, Volume: 2, Issue:4 Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Gastrins; Glucagon; Hormones, Ectopic; Humans; Male; Metyrapone; Microscopy, Electron; Neoplasm Metastasis; Radioimmunoassay; Streptozocin	1973
Accumulation and metabolism of 3H-epinephrine by the rat heart during variable states of adrenocortical function. Hormone research, 1974, Volume: 5, Issue:5 Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Catechols; Epinephrine; Heart; Hydrocortisone; Hypophysectomy; Male; Mandelic Acids; Methyl Ethers; Metyrapone; Myocardium; Pituitary Gland; Rats; Tritium; Vanilmandelic Acid	1974
The involvement of human placental microsomal cytochrome P-450 in aromatization. The Journal of biological chemistry, 1974, Sep-10, Volume: 249, Issue:17 Topics: Aminoglutethimide; Androstenedione; Animals; Binding Sites; Binding, Competitive; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Female; Humans; Kinetics; Metyrapone; Microsomes; Microsomes, Liver; Nandrolone; Placenta; Pregnancy; Proadifen; Protein Binding; Rabbits; Receptors, Cell Surface; Spectrophotometry; Spectrophotometry, Ultraviolet; Steroids; Swine; Tritium	1974
[Ultrastructure of the corticotrophic cells of the pituitary gland in rat following administration of steroidogenesis-inhibitors and methylprednisolone (author's transl)]. Virchows Archiv. A, Pathological anatomy and histology, 1974, Volume: 364, Issue:2 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Endoplasmic Reticulum; Glycyrrhiza; Golgi Apparatus; Injections, Intraperitoneal; Male; Methylprednisolone; Metyrapone; Microscopy, Electron; Pituitary Gland; Plants, Medicinal; Rats; Ribosomes; Succinates; Terpenes; Time Factors	1974
Treatment of Cushing's disease with adrenal blocking drugs and megavoltage therapy to the pituitary. Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:12 Pt 1 Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Female; Humans; Hydrocortisone; Male; Metyrapone; Middle Aged; Pituitary Irradiation; Pruritus; Psoriasis; Radiotherapy, High-Energy	1974
Effects of aminoglutethimide, metyrapone, and ascorbic acid on testicular metabolism of cholesterol. Metabolism: clinical and experimental, 1974, Volume: 23, Issue:12 Topics: Aminoglutethimide; Androstanes; Androstenedione; Animals; Ascorbic Acid; Carbon Radioisotopes; Cell-Free System; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Female; Hydroxyprogesterones; Hydroxysteroids; Male; Metyrapone; Mitochondria; Pregnenolone; Progesterone; Rats; Testis; Testosterone; Tritium	1974
Effect of exogenous steroids and inhibitors of steroidogenesis on endotoxin shock. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 142, Issue:2 Topics: Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Androstenedione; Animals; Butanones; Corticosterone; Desoxycorticosterone; Endotoxins; Hydrocortisone; Hydroxyprogesterones; Lethal Dose 50; Male; Metyrapone; Mice; Mice, Inbred ICR; Pregnenes; Pregnenolone; Progesterone; Shock, Septic	1973
Oxidation of 20 -hydroxycholesterol by adrenal cortex mitochondria. The Journal of biological chemistry, 1973, Jan-10, Volume: 248, Issue:1 Topics: Adrenal Glands; Aminoglutethimide; Animals; Antimycin A; Cattle; Cholesterol; Chromatography, Paper; Cyanides; Malates; Metyrapone; Mitochondria; Oxygen Consumption; Pregnenolone; Spectrophotometry; Succinates; Tritium	1973
The effect of adrenalectomy or pharmacological inhibition of adrenocortical function on macromolecule uptake by the new-born rat intestine. The Journal of physiology, 1973, Volume: 229, Issue:3 Topics: Adrenal Glands; Adrenalectomy; Aminoglutethimide; Animals; Animals, Newborn; Corticosterone; Hydrocortisone; Intestinal Absorption; Metyrapone; Organ Size; Povidone; Rats	1973
[Therapy of secondary hyperaldosteronism]. Minerva medica, 1973, Mar-14, Volume: 64, Issue:14 Topics: Aminoglutethimide; Butanones; Heparin; Humans; Hyperaldosteronism; Metyrapone; Mineralocorticoid Receptor Antagonists; Spironolactone; Triamterene; Triparanol	1973
[Drug therapy of adrenal gland hyperfunction]. Deutsche medizinische Wochenschrift (1946), 1972, Mar-24, Volume: 97, Issue:12 Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aminoglutethimide; Antimetabolites; Diagnosis, Differential; Dichlorodiphenyldichloroethane; Female; Glucocorticoids; Humans; Hydrocortisone; Metyrapone	1972
The influence of corticoids on the phenylethanolamine-N-methyl transferase activity in the adrenal glands of Gallus domesticus. General and comparative endocrinology, 1971, Volume: 17, Issue:1 Topics: Adrenal Glands; Adrenal Medulla; Aminoglutethimide; Analysis of Variance; Aniline Compounds; Animals; Chick Embryo; Chickens; Corticosterone; Dexamethasone; Epinephrine; Ethanol; Female; Male; Methyltransferases; Metyrapone; Norepinephrine; Stimulation, Chemical; Transferases	1971
The effect of steroid hydroxylase inhibitors on the rate of reduction of adrenal mitochondrial cytochrome P-450. Biochemical and biophysical research communications, 1969, Aug-15, Volume: 36, Issue:4 Topics: Adrenal Glands; Aminoglutethimide; Aniline Compounds; Animals; Butanones; Cattle; Cytochromes; Depression, Chemical; Kinetics; Malates; Metyrapone; Mitochondria; Mixed Function Oxygenases; Spectrophotometry; Steroids; Stimulation, Chemical	1969
Carcinoma of the adrenal cortex: clinical description, diagnosis, and treatment. International advances in surgical oncology, 1984, Volume: 7 Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Antineoplastic Agents; Combined Modality Therapy; Diagnosis, Differential; Humans; Metyrapone; Mitotane; Prognosis; Radiotherapy Dosage	1984
Cushing's disease in a patient with a 'nonfunctioning' pituitary tumor. Spontaneous development and remission. Archives of internal medicine, 1983, Volume: 143, Issue:5 Topics: Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Female; Humans; Metyrapone; Pituitary Function Tests; Pituitary Neoplasms	1983
Effects of steroid blockers on LH-induced ovulation in the domestic fowl, Gallus domesticus. Journal of reproduction and fertility, 1981, Volume: 61, Issue:2 Topics: Aminoglutethimide; Animals; Azacosterol; Chickens; Female; Gonadotropins, Equine; Luteinizing Hormone; Metyrapone; Ovulation; Ovulation Induction; Progesterone; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride	1981
Inhibition of lipid peroxidation by paraquat: site of inhibition in the cytochrome P-450-dependent steroid hydroxylase system from bovine adrenal cortex mitochondria. Biochemical and biophysical research communications, 1982, Jul-30, Volume: 107, Issue:2 Topics: Aminoglutethimide; Animals; Butanones; Cattle; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Lipid Peroxides; Metyrapone; Mitochondria; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Paraquat	1982
Regulation of hamster adrenal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. Endocrinology, 1980, Volume: 107, Issue:1 Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cholesterol; Cholesterol Esters; Cholesterol, Dietary; Circadian Rhythm; Cricetinae; Hydroxymethylglutaryl CoA Reductases; Kinetics; Male; Metyrapone; Mevalonic Acid; Subcellular Fractions	1980
The effect of exogenous steroids and steroid inhibitors on IgG transmissions in young rats. Biology of the neonate, 1980, Volume: 38, Issue:3-4 Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Corticosterone; Cortisone; Desoxycorticosterone; Hydrocortisone; Immunoglobulin G; Intestine, Small; Maternal Deprivation; Metyrapone; Rats; Succinates	1980
Relationships among adrenal weight, corticosterone, and stimulated adrenocorticotropin levels in rats. Endocrinology, 1983, Volume: 113, Issue:6 Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Corticosterone; Cyanoketone; Ether; Male; Metyrapone; Organ Size; Rats; Rats, Inbred Strains	1983
Effects of drugs and sterols on cholesterol 7 alpha-hydroxylase activity in rat liver microsomes. Journal of lipid research, 1983, Volume: 24, Issue:1 Topics: Aminoglutethimide; Animals; Ascorbic Acid; Bile Acids and Salts; Cholesterol 7-alpha-Hydroxylase; Cimetidine; Kinetics; Male; Metyrapone; Microsomes, Liver; Proadifen; Rats; Rats, Inbred Strains; Steroid Hydroxylases; Sterols	1983
An improved method for the extraction of corticosterone from cell homogenates and subcellular fractions of the rat adrenal cortex. Steroids, 1981, Volume: 37, Issue:5 Topics: Adrenal Cortex; Aminoglutethimide; Animals; Corticosterone; Ethanol; Imidazoles; Male; Metyrapone; Rats; Sodium Cyanide; Solvents; Subcellular Fractions	1981
[Cushing's syndrome. Medical treatment of adrenal hypercorticism]. Hormone research, 1980, Volume: 13, Issue:4-5 Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Androstanols; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dihydrotestosterone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Metyrapone; Mitotane; Nitriles	1980
In vitro study of frog (Rana ridibunda Pallas) interrenal function by use of a simplified perifusion system. IV. Influence of metyrapone and aminoglutethimide upon aldosterone production. General and comparative endocrinology, 1980, Volume: 42, Issue:4 Topics: Adrenal Glands; Aldosterone; Aminoglutethimide; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Interrenal Gland; Kinetics; Male; Metyrapone; Perfusion; Radioimmunoassay; Rana ridibunda	1980
Glucocorticoids enhance the cholesterol side-chain cleavage activity of ovine adrenocortical mitochondria. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:1 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adrenodoxin; Aminoglutethimide; Animals; Calcium Chloride; Cells, Cultured; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Ferredoxin-NADP Reductase; Glucocorticoids; Hydroxycholesterols; Metyrapone; Mitochondria; Pregnenolone; RNA, Messenger; Sheep; Steroids	1995
Adrenal carcinoma. Current therapy in endocrinology and metabolism, 1994, Volume: 5 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Diagnosis, Differential; Humans; Metyrapone; Mitotane; Neoplasm Metastasis	1994
An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione. The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:5 Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Aged; Aldehyde-Lyases; Aminoglutethimide; Androstenedione; Carcinoma; Child; Cytochrome P-450 Enzyme System; Female; Humans; Hyperaldosteronism; Male; Metyrapone; Middle Aged; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase	1995
The psychotropic effects of inhibitors of steroid biosynthesis in depressed patients refractory to treatment. Biological psychiatry, 1995, Mar-15, Volume: 37, Issue:6 Topics: Adrenal Cortex Hormones; Adult; Aminoglutethimide; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ketoconazole; Male; Metyrapone; Middle Aged; Personality Inventory; Psychotic Disorders	1995
Effect of dexamethasone and cytochrome P450 inhibitors on the formation of 7 alpha-hydroxydehydroepiandrosterone by human adipose stromal cells. The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:5-6 Topics: Adipose Tissue; Aminoglutethimide; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Dexamethasone; Humans; Ketoconazole; Metyrapone; Mifepristone; Stromal Cells	1994
Competition for electron transfer between cytochromes P450scc and P45011 beta in rat adrenal mitochondria. Molecular and cellular endocrinology, 1993, Volume: 95, Issue:1-2 Topics: Adrenal Cortex; Adrenodoxin; Aminoglutethimide; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cosyntropin; Desoxycorticosterone; Electron Transport; Female; Ferredoxin-NADP Reductase; Isocitrates; Isoenzymes; Metyrapone; Mitochondria; NADP; Oxidation-Reduction; Pregnenolone; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase; Succinates; Succinic Acid	1993
Stress response and drug metabolism in mice. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1996, Volume: 30, Issue:2 Topics: Adrenalectomy; Aminoglutethimide; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Corticosterone; Enzyme Inhibitors; Injections, Intraperitoneal; Liver; Male; Metyrapone; Mice; Saline Solution, Hypertonic; Stress, Physiological	1996
Acquired immune deficiency syndrome: the glucocorticoid solution. Medical hypotheses, 1996, Volume: 47, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Adrenocorticotropic Hormone; Aminoglutethimide; CD8-Positive T-Lymphocytes; Corticotropin-Releasing Hormone; Glucocorticoids; HIV; HIV Envelope Protein gp120; Humans; Hydrocortisone; Interleukin-1; Lymphocyte Activation; Metyrapone; Mitotane; Models, Biological; Receptors, Pituitary Hormone; T-Lymphocytes	1996
Effects of corticosteroid synthesis inhibitors on the sensitization of reward by food restriction. Brain research, 1996, Jul-08, Volume: 726, Issue:1-2 Topics: Adrenal Glands; Aminoglutethimide; Animals; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Electric Stimulation; Enzyme Inhibitors; Evaluation Studies as Topic; Food Deprivation; Hypothalamic Area, Lateral; Male; Metyrapone; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation	1996
The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033)--a potent, selective aromatase inhibitor. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:4 Topics: Adrenal Glands; Aminoglutethimide; Anastrozole; Androstenedione; Animals; Aromatase Inhibitors; Cortodoxone; Enzyme Inhibitors; Fadrozole; Female; Hormones; Humans; Macaca nemestrina; Male; Metyrapone; Nitriles; Organ Size; Potassium; Prostate; Rats; Rats, Wistar; Seminal Vesicles; Sodium; Triazoles; Uterus	1996
The corticosteroid synthesis inhibitors metyrapone and aminoglutethimide impair long-term memory for a passive avoidance task in day-old chicks. Brain research, 1997, Sep-26, Volume: 769, Issue:2 Topics: Adrenal Cortex Hormones; Aminoglutethimide; Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Female; Male; Memory; Metyrapone	1997
Aminoglutethimide suppresses adrenocorticotropin receptor expression in the NCI-h295 adrenocortical tumor cell line. The Journal of endocrinology, 1998, Volume: 159, Issue:1 Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Analysis of Variance; Cell Division; Cholesterol Side-Chain Cleavage Enzyme; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Humans; Hydrocortisone; Metyrapone; Receptors, Corticotropin; RNA, Messenger; Steroid 11-beta-Hydroxylase; Tumor Cells, Cultured	1998
Attenuation of hypothalamic-pituitary-adrenal axis stress responses in late pregnancy: changes in feedforward and feedback mechanisms. Journal of neuroendocrinology, 2000, Volume: 12, Issue:8 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Analysis of Variance; Animals; Area Under Curve; Corticosterone; Corticotropin-Releasing Hormone; Feedback; Female; Glycyrrhetinic Acid; Hippocampus; Hydroxysteroid Dehydrogenases; Hypothalamo-Hypophyseal System; Metyrapone; Paraventricular Hypothalamic Nucleus; Pituitary Gland, Anterior; Pituitary-Adrenal System; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Stress, Physiological; Vasopressins	2000
Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis. Toxicology, 2001, Aug-28, Volume: 165, Issue:2-3 Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aminoglutethimide; Animals; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Dogs; Female; Ketoconazole; Metyrapone; Miconazole; Mitotane; Toxicity Tests	2001
Cold-induced increment in rat adrenal gland type II deiodinase is corticosterone dependent. Endocrine, 2001, Volume: 15, Issue:1 Topics: Adrenal Glands; Aminoglutethimide; Animals; Binding, Competitive; Cholesterol Side-Chain Cleavage Enzyme; Cold Temperature; Corticosterone; Enzyme Inhibitors; Iodide Peroxidase; Iodine Radioisotopes; Male; Metyrapone; Organ Size; Rats; Rats, Wistar; Steroid 11-beta-Hydroxylase	2001
Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:2 Topics: Adrenal Cortex Neoplasms; Aminoglutethimide; Carcinoma; Chromatography, High Pressure Liquid; Colforsin; Cytochrome P-450 Enzyme Inhibitors; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Drug Combinations; Environmental Pollutants; Enzyme Inhibitors; Hydrocortisone; Ketoconazole; Metyrapone; Tumor Cells, Cultured	2002
Surgical and pharmacological suppression of glucocorticoids prevents the enhancement of morphine conditioned place preference by uncontrollable stress in rats. Psychopharmacology, 2005, Volume: 179, Issue:2 Topics: Adrenalectomy; Aminoglutethimide; Animals; Behavior, Animal; Conditioning, Operant; Electroshock; Glucocorticoids; Hormone Antagonists; Hydrocortisone; Male; Metyrapone; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Stress, Psychological	2005
The H295R system for evaluation of endocrine-disrupting effects. Ecotoxicology and environmental safety, 2006, Volume: 65, Issue:3 Topics: Aminoglutethimide; Biological Assay; Cell Line, Tumor; Colforsin; Drug Interactions; Endocrine Disruptors; Estradiol; Gene Expression Profiling; Gene Expression Regulation; Humans; Ketoconazole; Metyrapone; Progesterone; Testosterone	2006
Prolonged remission of severe Cushing syndrome without adrenalectomy in an infant with McCune-Albright syndrome. The Journal of pediatrics, 2008, Volume: 152, Issue:6 Topics: Adrenalectomy; Adrenergic Agents; Aminoglutethimide; Child; Cushing Syndrome; Enzyme Inhibitors; Female; Fibrous Dysplasia, Polyostotic; Follow-Up Studies; Humans; Infant; Metyrapone; Remission Induction; Severity of Illness Index; Time Factors	2008
Ketoconazole treatment for Cushing syndrome in McCune-Albright syndrome. The Journal of pediatrics, 2009, Volume: 154, Issue:3 Topics: Adrenergic Agents; Adrenocorticotropic Hormone; Aminoglutethimide; Antifungal Agents; Chemical and Drug Induced Liver Injury; Cushing Syndrome; Enzyme Inhibitors; Female; Fibrous Dysplasia, Polyostotic; Humans; Hydrocortisone; Infant; Ketoconazole; Liver Function Tests; Metyrapone; Remission Induction	2009
Pharmacological suppression of endogenous glucocorticoid synthesis attenuated blood pressure and heart rate response to acute restraint in Wistar rats. Physiological research, 2020, 07-16, Volume: 69, Issue:3 Topics: Adrenalectomy; Aminoglutethimide; Animals; Antimetabolites; Aromatase Inhibitors; Blood Pressure; Disease Models, Animal; Glucocorticoids; Heart Rate; Male; Metyrapone; Rats; Rats, Wistar; Restraint, Physical; Vascular Resistance	2020