aminoglutethimide and methotrexate

aminoglutethimide has been researched along with methotrexate in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Boogerd, W; Bruning, PF; Kröger, R; Somers, R; van der Sande, JJ1
Boucher, AE; Drago, J; Gordon, R; Harvey, H; Lipton, A; Manni, A; Rohner, T; Santen, RJ; Simmonds, M; Wettlaufer, J1
Dabag, S; Rieche, K; Scharlau, L1
Grisold, W; Lutz, D; Mamoli, B; Mokrusa, W; Weber, R1
Graziottin, A; Marchetti, M; Onnis, A; Velasco, M1
Mattheiem, W; Mouridsen, HT; Palshof, T; Paridaens, RJ; Rotmensz, N; Sylvester, RJ1
Holland, JF; Perlow, LS1
Bezwoda, WR; Browde, S; Derman, DP; Goss, G; Lange, M1
Costanza, ME1
Branković-Magić, MV; Mitrovic, LB; Nesković-Konstantinović, ZB; Nikolić-Vukosavljević, DB; Spuzić, I1
Dietze, O; Filipits, M; Gnant, MF; Greil, R; Grill, R; Huynh, A; Jakesz, R; Kwasny, W; Lax, S; Lehnert, M; Rudas, M; Schippinger, W; Singer, C; Stierer, M; Stiglbauer, W1

Reviews

2 review(s) available for aminoglutethimide and methotrexate

ArticleYear
Introduction to chemotherapy and antineoplastic pharmacology in breast cancer.
    European journal of gynaecological oncology, 1982, Volume: 3, Issue:1

    Topics: Aminoglutethimide; Androgens; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Estrogen Antagonists; Estrogens; Female; Fluorouracil; Glucocorticoids; Humans; Male; Methotrexate; Palliative Care; Progestins; Receptors, Estrogen; Receptors, Progesterone

1982
Chemotherapy of breast cancer.
    Medical oncology and tumor pharmacotherapy, 1984, Volume: 1, Issue:3

    Topics: Adrenalectomy; Alkylating Agents; Aminoglutethimide; Androgens; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Estrogens; Female; Fluorouracil; Humans; Immunotherapy; Methotrexate; Naphthacenes; Pituitary Hormone-Releasing Hormones; Progestins; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Vinca Alkaloids

1984

Trials

4 trial(s) available for aminoglutethimide and methotrexate

ArticleYear
Androgen depletion and repletion as a means of potentiating the effect of cytotoxic chemotherapy in advanced prostate cancer.
    Journal of steroid biochemistry, 1987, Volume: 27, Issue:1-3

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Synergism; Fluorouracil; Fluoxymesterone; Humans; Hydrocortisone; Male; Methotrexate; Orchiectomy; Prostatic Neoplasms; Random Allocation; Spinal Cord Compression

1987
Currently active protocols in the EORTC Breast Cancer Cooperative Group.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1984, Volume: 91

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Receptors, Estrogen; Tamoxifen

1984
Content of epidermal growth factor receptor in metastatic breast cancer: its role in endocrine sensitivity prediction.
    Neoplasma, 2000, Volume: 47, Issue:2

    Topics: Adult; Aminoglutethimide; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; ErbB Receptors; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Ovariectomy; Predictive Value of Tests; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tamoxifen; Treatment Outcome

2000
Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Mar-15, Volume: 14, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclin D1; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Goserelin; Humans; Methotrexate; Middle Aged; Prognosis; Receptors, Cytoplasmic and Nuclear; Recurrence; Tamoxifen; Treatment Outcome

2008

Other Studies

12 other study(ies) available for aminoglutethimide and methotrexate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effective systemic therapy for spinal epidural metastases from breast carcinoma.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:1

    Topics: Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Epidural Neoplasms; Female; Fluorouracil; Humans; Hydrocortisone; Methotrexate; Middle Aged; Radiography

1989
[Combination of aminoglutethimide and polychemotherapy for the treatment of predominant bone metastasis in breast cancer].
    Deutsche medizinische Wochenschrift (1946), 1986, Nov-07, Volume: 111, Issue:45

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Vinblastine; Vincristine

1986
[Acute myelomonocytic and monoblastic leukemia with polyradicular symptoms].
    Wiener klinische Wochenschrift, 1985, Aug-30, Volume: 97, Issue:16

    Topics: Abducens Nerve; Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebral Hemorrhage; Cerebrospinal Fluid; Cranial Nerve Diseases; Cytarabine; Danazol; Demyelinating Diseases; Facial Paralysis; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Meningism; Methotrexate; Middle Aged; Spinal Nerve Roots; Tamoxifen

1985
Treatment of advanced breast cancer with aminoglutethimide--response after previous tamoxifen treatment.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Sep-08, Volume: 66, Issue:10

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Fluoxymesterone; Humans; Menopause; Methotrexate; Tamoxifen; Time Factors

1984
The medical management of breast cancer.
    Clinical obstetrics and gynecology, 1982, Volume: 25, Issue:2

    Topics: Adjuvants, Pharmaceutic; Adult; Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hypophysectomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Receptors, Estrogen; Tamoxifen

1982