aminoglutethimide and medroxyprogesterone acetate

aminoglutethimide has been researched along with medroxyprogesterone acetate in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199024 (58.54)18.7374
1990's12 (29.27)18.2507
2000's1 (2.44)29.6817
2010's4 (9.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Abe, K1
Clavel, M1
Focan, C1
Namer, M1
Bezwoda, WR1
Biakhov, MIu; Meshcheriakova, NG; Vasiuta, NIu; Voznyĭ, EK1
Bye, A; Cranny, A; Daly, PA; Feely, J; Halpenny, O1
Berger, U; Coombes, RC; McClelland, RA; Miller, LS; Powles, TJ1
Di Lauro, L; Lazzaro, B; Lopez, M; Papaldo, P1
Samonigg, H1
Enomoto, K; Fukutomi, T; Ikeda, T; Ishibiki, K; Isobe, Y; Kikuyama, S; Kubota, T; Nakamura, A; Nishiumi, T; Shimada, A1
Amalfitano, TG; Chumas, JC; Mann, WJ; Mazella, J; Stone, ML; Sun, B; Tseng, JK; Tseng, L; Wallach, RC1
Kvinssland, S; Lønning, PE; Ueland, PM1
Blossey, HC; Kleeberg, U; Nagel, GA; Wander, HE1
Manni, A1
Jonat, W; Maass, H1
Blossey, HC; Essers, U; Kleeberg, UR; Nagel, GA; Wander, HE1
Petru, E; Schmähl, D1
Kvinnsland, S; Lönning, PE; Lundgren, S; Wiedemann, G1
Canney, PA; Griffiths, T; Latief, TN; Mould, JJ; Priestman, TJ; Spooner, D1
Blijham, GH; Mellink, WA; Meulenberg, PM; Van Deijk, WA1
Cremer, P; Kruse, B; Kuhn, W; Nagel, GA; Seidel, D; Teichmann, AT; Wander, HE; Wieland, H1
Kaiser, R; Schulz, KD1
Blossey, HC; Nagel, GA; Wander, HE1
Ingle, JN1
Battelli, T; Ginnetti, A; Guistini, L; Manocchi, P; Mattioli, R1
Carlström, K; Döberl, A; Pousette, A; Rannevik, G; Wilking, N1
Kauppila, A1
Garbrecht, M; Kleeberg, UR; Müllerleile, U; Pompecki, R; Treidler, J1
Blossey, HC; Kleeberg, U; Köbberling, J; Nagel, GA; Wander, HE1
Evans, CA; Kennedy, TG1
Espié, M2
Ayme, Y; Carton, M; Daban, A; Delozier, T; Fargeot, P; Ferri, L; Fumoleau, P; Garcia-Giralt, E; Gorins, A; Omodei Zorini, C1
Ahern, J; Iveson, TJ; Smith, IE1
Ayme, Y; Carton, M; Daban, A; Delozier, T; Fargeot, P; Fumoleau, P; Garcia-Giralt, E; Gorins, A; Guerin, D; Guerin, R1

Reviews

6 review(s) available for aminoglutethimide and medroxyprogesterone acetate

ArticleYear
[Hormone therapy of neoplasms].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Mar-10, Volume: 80, Issue:3

    Topics: Adenoma, Islet Cell; Aminoglutethimide; Breast Neoplasms; Female; Fluoxymesterone; Humans; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Pancreatic Neoplasms; Prostatic Neoplasms; Tamoxifen

1991
Management of breast cancer with bone metastases.
    Bone, 1991, Volume: 12 Suppl 1

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Estrogens; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Neoplasms, Hormone-Dependent; Palliative Care; Survival Rate

1991
[Adjuvant hormone therapy of primary breast cancer. Review of the literature].
    Revue medicale de Liege, 1991, Volume: 46, Issue:5

    Topics: Amenorrhea; Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Delayed-Action Preparations; Female; Gonadotropin-Releasing Hormone; Hormones; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Tamoxifen

1991
Tamoxifen therapy of metastatic breast cancer.
    The Journal of laboratory and clinical medicine, 1987, Volume: 109, Issue:3

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Female; Humans; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Neoplasm Metastasis; Random Allocation; Tamoxifen

1987
Progestin therapy of endometrial, breast and ovarian carcinoma. A review of clinical observations.
    Acta obstetricia et gynecologica Scandinavica, 1984, Volume: 63, Issue:5

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bromocriptine; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Forecasting; Humans; Hydroxyprogesterones; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Neoplasm Recurrence, Local; Ovarian Neoplasms; Progestins; Receptors, Steroid; Uterine Neoplasms

1984
[Hormonal therapy of breast cancer].
    Bulletin du cancer, 1994, Volume: 81, Issue:10 Suppl

    Topics: Aminoglutethimide; Breast Neoplasms; Female; Gonadotropin-Releasing Hormone; Humans; Medroxyprogesterone Acetate; Ovariectomy; Tamoxifen

1994

Trials

7 trial(s) available for aminoglutethimide and medroxyprogesterone acetate

ArticleYear
Treatment of stage D2 prostatic cancer refractory to or relapsed following castration plus oestrogens. Comparison of aminoglutethimide plus hydrocortisone with medroxyprogesterone acetate plus hydrocortisone.
    British journal of urology, 1990, Volume: 66, Issue:2

    Topics: Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Diethylstilbestrol; Humans; Hydrocortisone; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Neoplasm Staging; Orchiectomy; Postoperative Period; Prostatic Neoplasms; Randomized Controlled Trials as Topic

1990
Tamoxifen therapy of metastatic breast cancer.
    The Journal of laboratory and clinical medicine, 1987, Volume: 109, Issue:3

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Female; Humans; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Neoplasm Metastasis; Random Allocation; Tamoxifen

1987
[Aminoglutethimide plus high-dose medroxyprogesterone acetate versus aminoglutethimide plus cortisone in therapy of metastasizing breast cancer. An AIO phase III study].
    Onkologie, 1987, Volume: 10, Issue:5

    Topics: Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cortisone; Drug Therapy, Combination; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Neoplasm Metastasis; Random Allocation

1987
Randomized trial comparing aminoglutethimide with high-dose medroxyprogesterone acetate in therapy for advanced breast carcinoma.
    Journal of the National Cancer Institute, 1988, Sep-21, Volume: 80, Issue:14

    Topics: Aminoglutethimide; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Random Allocation; Tamoxifen; Time Factors

1988
Additive hormonal therapy in women with advanced breast cancer.
    Cancer, 1984, Feb-01, Volume: 53, Issue:3 Suppl

    Topics: Aminoglutethimide; Androgens; Breast Neoplasms; Clinical Trials as Topic; Danazol; Drug Therapy, Combination; Estrogens; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Hypophysectomy; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Random Allocation; Tamoxifen

1984
[2d and 3d line hormonal therapy in postmenopausal metastatic breast tumor. Comparison of medroxyprogesterone acetate and aminoglutethimide in tamoxifen-resistant patients].
    La Clinica terapeutica, 1994, Volume: 145, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Breast Neoplasms; Drug Resistance; Female; Humans; Lymphatic Metastasis; Medroxyprogesterone Acetate; Menopause; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Tamoxifen; Time Factors

1994
Second and third line hormonotherapy in advanced post-menopausal breast cancer: a multicenter randomized trial comparing medroxyprogesterone acetate with aminoglutethimide in patients who have become resistant to tamoxifen.
    Breast cancer research and treatment, 1992, Volume: 24, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Breast Neoplasms; Drug Resistance; Female; Humans; Medroxyprogesterone Acetate; Menopause; Middle Aged; Prospective Studies; Tamoxifen; Time Factors; Treatment Outcome

1992

Other Studies

29 other study(ies) available for aminoglutethimide and medroxyprogesterone acetate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Reflexions on hormone therapy of cancer of the breast].
    Bulletin du cancer, 1991, Volume: 78, Issue:11 Suppl

    Topics: Aminoglutethimide; Androgens; Breast Neoplasms; Estrogens; Female; Humans; Medroxyprogesterone Acetate; Menopause; Neoplasm Metastasis; Ovariectomy; Tamoxifen

1991
[Hormonal control of disseminated breast cancer].
    Sovetskaia meditsina, 1990, Issue:6

    Topics: Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Delayed-Action Preparations; Estrogen Antagonists; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Middle Aged; Neoplasm Metastasis; Tamoxifen

1990
Influence of aminoglutethimide on plasma levels of medroxyprogesterone acetate.
    Medical oncology and tumor pharmacotherapy, 1990, Volume: 7, Issue:4

    Topics: Adult; Aged; Aminoglutethimide; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Administration Schedule; Drug Interactions; Drug Resistance; Female; Humans; Hydrocortisone; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Survival Rate

1990
Immunocytochemical assay for estrogen receptor in patients with breast cancer: relationship to a biochemical assay and to outcome of therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8

    Topics: Aminoglutethimide; Antibodies, Monoclonal; Breast Neoplasms; Combined Modality Therapy; Dextrans; Female; Histocytochemistry; Humans; Immunoenzyme Techniques; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Prognosis; Receptors, Estrogen; Staining and Labeling; Tamoxifen

1986
Hormonal treatment of disseminated male breast cancer.
    Oncology, 1985, Volume: 42, Issue:6

    Topics: Adult; Aminoglutethimide; Androgen Antagonists; Antineoplastic Agents; Breast Neoplasms; Castration; Cyproterone; Cyproterone Acetate; Estrogens; Hormones; Humans; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Neoplasm Recurrence, Local; Tamoxifen; Time Factors

1985
[Value of hormone therapy in metastasizing breast cancer].
    Wiener medizinische Wochenschrift (1946), 1985, Dec-31, Volume: 135, Issue:23-24

    Topics: Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Neoplasm Metastasis; Ovariectomy; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

1985
Experimental combined hormone therapy on human breast carcinomas serially transplanted into nude mice.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:1

    Topics: Adult; Aminoglutethimide; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Estradiol; Female; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Organ Size; Tamoxifen; Transplantation, Heterologous; Uterus

1986
Endocrine aspects of human uterine sarcoma: a preliminary study.
    American journal of obstetrics and gynecology, 1986, Volume: 155, Issue:1

    Topics: Adult; Aged; Aminoglutethimide; Animals; Aromatase; Aromatase Inhibitors; Cells, Cultured; Estradiol; Female; Humans; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Mice; Mice, Nude; Middle Aged; Nandrolone; Neoplasm Transplantation; Progesterone; Receptors, Estrogen; Receptors, Progesterone; Sarcoma; Uterine Neoplasms

1986
Aminoglutethimide as an inducer of microsomal enzymes. Part 1: Pharmacological aspects.
    Breast cancer research and treatment, 1986, Volume: 7 Suppl

    Topics: Aminoglutethimide; Antipyrine; Dexamethasone; Digitoxin; Drug Interactions; Enzyme Activation; Humans; Kinetics; Medroxyprogesterone; Medroxyprogesterone Acetate; Microsomes; Theophylline; Warfarin

1986
Aminoglutethimide and medroxyprogesterone acetate in the treatment of patients with advanced breast cancer. A phase II study of the Association of Medical Oncology of the German Cancer Society (AIO).
    Cancer, 1986, Nov-01, Volume: 58, Issue:9

    Topics: Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Drug Evaluation; Drug Synergism; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Middle Aged; Neoplasm Metastasis; Pain

1986
[Endocrine therapy of breast cancer].
    Zentralblatt fur Gynakologie, 1987, Volume: 109, Issue:10

    Topics: Aminoglutethimide; Antibodies, Monoclonal; Breast Neoplasms; Combined Modality Therapy; Female; Hormones; Humans; Lymphatic Metastasis; Medroxyprogesterone; Medroxyprogesterone Acetate; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

1987
On the role of additive hormone monotherapy with tamoxifen, medroxyprogesterone acetate and aminoglutethimide, in advanced breast cancer.
    Klinische Wochenschrift, 1987, Oct-15, Volume: 65, Issue:20

    Topics: Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Tamoxifen

1987
[Which hormone therapy should be used in advanced breast carcinoma in males?].
    Deutsche medizinische Wochenschrift (1946), 1988, Sep-02, Volume: 113, Issue:35

    Topics: Adenocarcinoma; Aged; Aminoglutethimide; Axilla; Breast Neoplasms; Dexamethasone; Drug Evaluation; Humans; Lymphatic Metastasis; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Tamoxifen; Testolactone; Testosterone Congeners

1988
Influence of aminoglutethimide on plasma levels of medroxyprogesterone acetate: its correlation with serum cortisol.
    Cancer treatment reports, 1985, Volume: 69, Issue:1

    Topics: Aminoglutethimide; Breast Neoplasms; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Neoplasm Metastasis; Pilot Projects

1985
[Changes in serum lipoproteins under hormonal therapy of breast carcinoma and other endocrine-dependent tumors].
    Onkologie, 1985, Volume: 8, Issue:2

    Topics: Aminoglutethimide; Breast Neoplasms; Cholesterol; Cortisone; Drug Therapy, Combination; Female; Humans; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Triglycerides

1985
[Current status of drug treatment of endometrial carcinoma].
    Der Gynakologe, 1983, Volume: 16, Issue:2

    Topics: Aminoglutethimide; Antineoplastic Agents; Estrogen Antagonists; Female; Humans; Immunotherapy; Medroxyprogesterone; Medroxyprogesterone Acetate; Palliative Care; Patient Care Planning; Uterine Neoplasms

1983
[Medroxyprogesterone acetate (MAP) and aminoglutethimide (AG) in metastatic breast carcinoma. Preliminary report on a phase II study of the German Cancer Society's Internal Medicine Oncology Task Force].
    Onkologie, 1982, Volume: 5 Suppl

    Topics: Adult; Aged; Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Delayed-Action Preparations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Neoplasm Metastasis

1982
[Medical treatment of the breast].
    Minerva medica, 1984, Feb-18, Volume: 75, Issue:6

    Topics: Adrenal Cortex Hormones; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Castration; Estrogen Antagonists; Female; Gonadal Steroid Hormones; Humans; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Time Factors

1984
Inhibition of steroid sulfatase activity by danazol.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 123

    Topics: Aminoglutethimide; Breast Neoplasms; Carcinoma; Culture Techniques; Danazol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estrogen Antagonists; Estrone; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Pregnadienes; Tamoxifen

1984
[Prognostic value of serum CEA and therapy-induced nonspecific CEA levels in metastasizing breast carcinoma].
    Onkologie, 1984, Volume: 7, Issue:6

    Topics: Adult; Aged; Alkaline Phosphatase; Aminoglutethimide; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoembryonic Antigen; Female; Hormones; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Neoplasm Metastasis; Prognosis

1984
[Medroxyprogesterone acetate as glucocorticoid in combination with aminoglutethimide in the treatment of metastatic breast cancer].
    Onkologie, 1982, Volume: 5 Suppl

    Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Medroxyprogesterone; Medroxyprogesterone Acetate

1982
Blastocyst implantation in ovariectomized, adrenalectomized hamsters treated with inhibitors of steroidogenesis during the pre-implantation period.
    Steroids, 1980, Volume: 36, Issue:1

    Topics: Adrenalectomy; Aminoglutethimide; Animals; Blastocyst; Castration; Cricetinae; Cyanoketone; Embryo Implantation; Embryonic Development; Estradiol; Estrone; Female; Medroxyprogesterone; Medroxyprogesterone Acetate; Mesocricetus; Ovary; Pregnancy; Progesterone; Prostaglandins; Uterus

1980
Megestrol acetate in advanced breast carcinoma.
    Oncology, 1994, Volume: 51 Suppl 1

    Topics: Aminoglutethimide; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Cross-Over Studies; Female; Humans; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Postmenopause; Prospective Studies; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome

1994
Response to third-line endocrine treatment for advanced breast cancer.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Medroxyprogesterone Acetate; Middle Aged; Neoplasm Staging; Retrospective Studies; Treatment Outcome

1993