Compounds > aminoglutethimide

aminoglutethimide and lovastatin

aminoglutethimide has been researched along with lovastatin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Hammond, JM; Kao, LC; Spicer, LJ; Strauss, JF1
Collins, DC; Hou, JW; Schleicher, RL1
Reimers, TJ; Ullmann, MB1
Getz, GS; Larsen, AL; Schreiber, JR; Wyne, KL1
de Greef, WJ; Jansen, H1
Cascio, C; Guarneri, P; Guarneri, R; Papadopoulos, V; Pavasant, P; Piccoli, F1

Other Studies

11 other study(ies) available for aminoglutethimide and lovastatin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
2-hydroxyestradiol enhanced progesterone production by porcine granulosa cells: dependence on de novo cholesterol synthesis and stimulation of cholesterol side-chain cleavage activity and cytochrome P450scc messenger ribonucleic acid levels.
    Endocrinology, 1990, Volume: 127, Issue:6

    Topics: Aminoglutethimide; Animals; Cells, Cultured; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Epinephrine; Estradiol; Estrogens, Catechol; Female; Follicle Stimulating Hormone; Granulosa Cells; Kinetics; Lovastatin; Luteinizing Hormone; Progesterone; RNA, Messenger; Swine

1990
Sources of cholesterol for testosterone biosynthesis in murine Leydig cells.
    Endocrinology, 1990, Volume: 127, Issue:5

    Topics: Aminoglutethimide; Animals; Cholesterol; Cholesterol, HDL; Hydroxymethylglutaryl CoA Reductases; Intracellular Membranes; Leydig Cells; Lovastatin; Male; Mice; Mice, Inbred C57BL; Sterols; Testosterone

1990
Progesterone production by binucleate trophoblastic cells of cows.
    Journal of reproduction and fertility. Supplement, 1989, Volume: 37

    Topics: Aminoglutethimide; Animals; Calcimycin; Calcium; Calmodulin; Cattle; Cells, Cultured; Cholesterol, HDL; Cholesterol, LDL; Female; Lovastatin; Pregnancy; Pregnancy, Animal; Progesterone; Sterols; Trifluoperazine; Trophoblasts

1989
Rat granulosa cell apolipoprotein E secretion. Regulation by cell cholesterol.
    The Journal of biological chemistry, 1989, Oct-05, Volume: 264, Issue:28

    Topics: Aminoglutethimide; Animals; Apolipoproteins E; Cells, Cultured; Cholera Toxin; Cholesterol; Female; Granulosa Cells; Kinetics; Lovastatin; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate

1989
L-type lipase activity in ovaries of superovulated rats. Relation to cholesterol homeostasis.
    Molecular and cellular endocrinology, 1988, Volume: 57, Issue:1-2

    Topics: Aminoglutethimide; Animals; Cholesterol; Female; Homeostasis; Lipase; Lipids; Lovastatin; Ovary; Ovulation; Rats; Simvastatin; Superovulation

1988
Neurosteroidogenesis in rat retinas.
    Journal of neurochemistry, 1994, Volume: 63, Issue:1

    Topics: Aminoglutethimide; Animals; Central Nervous System; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, High Pressure Liquid; Cyclic AMP; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Immunohistochemistry; Lovastatin; Male; Neurotransmitter Agents; Pregnenolone; Progesterone; Rats; Rats, Wistar; Retina; Steroids; Time Factors

1994