aminoglutethimide has been researched along with flutamide in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (40.00) | 18.7374 |
| 1990's | 5 (20.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 7 (28.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Béland, L; Bélanger, A; Cusan, L; Dupont, A; Labrie, F; Lachance, R; Lacourcière, Y | 1 |
| Dauvois, S; Labrie, F | 1 |
| Bélanger, A; Caron, S; Labrie, F; Lacoste, D | 1 |
| Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Emond, J; Labrie, F; Lacourciere, Y; Pinault, S; Turina, E | 1 |
| Gangnerau, MN; Picon, R | 1 |
| Fair, WR; Sogani, PC | 1 |
| Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F | 1 |
| Belanger, A; Caron, S; Labrie, F; Lacoste, D; St-Arnaud, R | 1 |
| Benz, C; Hollander, C; Miller, B | 1 |
| Jacobi, GH; Wenderoth, UK | 1 |
| Soloway, MS | 1 |
| Cooper, M; Figg, WD; Headlee, D; Linehan, WM; Myers, CE; Sartor, O; Steinberg, S; Thibault, A; Tompkins, A; Weinberger, M | 1 |
| Kelly, WK; Nanus, D; Scher, HI; Zhang, ZF | 1 |
| Chuzel, F; Clark, AM; Saez, JM; Sanchez, P | 1 |
| Brawley, O; Dawson, N; Figg, WD; Lush, RM; Middleman, MN; Reed, E; Sartor, O; Senderowicz, A; Steinberg, SH; Tompkins, A | 1 |
| Aisaki, KI; Hatori, M; Igarashi, K; Kanno, J; Miki, Y; Nakamura, Y; Sasano, H; Sawai, T; Suzuki, T; Uzuki, M | 1 |
| Centurión, D; Cobos-Puc, LE; González-Hernández, A; Maassenvandenbrink, A; Muñoz-Islas, E; Ramírez-Rosas, MB; Sánchez-López, A; Villalón, CM | 1 |
3 review(s) available for aminoglutethimide and flutamide
| Article | Year |
|---|---|
Treatment of advanced prostatic cancer.
Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors | 1987 |
New forms and future perspectives in endocrine treatment of prostatic carcinoma.
Topics: Aminoglutethimide; Androgen Antagonists; Cyproterone; Cyproterone Acetate; Estrogen Antagonists; Flutamide; Hormones; Humans; Male; Pituitary Hormone-Releasing Hormones; Prolactin; Prostatic Neoplasms | 1984 |
Hormone and antihormone withdrawal: implications for the management of androgen-independent prostate cancer.
Topics: Aminoglutethimide; Androgen Antagonists; Clinical Trials as Topic; Flutamide; Humans; Male; Neoplasm Recurrence, Local; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms | 1996 |
1 trial(s) available for aminoglutethimide and flutamide
| Article | Year |
|---|---|
Treatment of advanced prostatic cancer.
Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors | 1987 |
22 other study(ies) available for aminoglutethimide and flutamide
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Complete response to combination therapy with an LHRH agonist and flutamide in metastatic male breast cancer: a case report.
Topics: Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Female; Flutamide; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Male | 1990 |
Androstenedione and androst-5-ene-3 beta,17 beta-diol stimulate DMBA-induced rat mammary tumors--role of aromatase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Androstenediol; Androstenediols; Androstenedione; Animals; Aromatase; Female; Flutamide; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Inbred Strains; Silicone Elastomers | 1989 |
Effect of 3-week treatment with [D-Trp6, des-Gly-NH10(2)]LHRH ethylamide, aminoglutethimide, ketoconazole or flutamide alone or in combination on testicular, serum, adrenal and prostatic steroid levels in the dog.
Topics: Adrenal Glands; Aminoglutethimide; Androgens; Animals; Dogs; Flutamide; Gonadotropin-Releasing Hormone; Ketoconazole; Male; Prostate; Testis; Triptorelin Pamoate | 1989 |
Anti-hormone treatment for prostate cancer relapsing after treatment with flutamide and castration. Addition of aminoglutethimide and low dose hydrocortisone to combination therapy.
Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Flutamide; Humans; Hydrocortisone; Male; Neoplasm Recurrence, Local; Orchiectomy; Prostatic Neoplasms | 1989 |
Onset of steroidogenesis and differentiation of functional LH receptors in rat fetal testicular cultures.
Topics: Aminoglutethimide; Animals; Binding, Competitive; Bucladesine; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Flutamide; Gestational Age; Luteinizing Hormone; Male; Organ Culture Techniques; Progesterone; Rats; Rats, Inbred Strains; Receptors, LH; Testis; Testosterone | 1987 |
Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate.
Topics: Aged; Aminoglutethimide; Androstane-3,17-diol; Androstanols; Androsterone; Anilides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flutamide; Glucuronates; Humans; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms | 1987 |
The rise in testicular androgens during the first days of treatment with an LHRH agonist in the dog can be blocked by aminoglutethimide or ketoconazole.
Topics: Aldehyde-Lyases; Aminoglutethimide; Androgens; Animals; Cytochrome P-450 Enzyme Inhibitors; Dogs; Estradiol; Flutamide; Gonadotropin-Releasing Hormone; Ketoconazole; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Testis; Testosterone; Triptorelin Pamoate | 1988 |
Endocrine-responsive pancreatic carcinoma: steroid binding and cytotoxicity studies in human tumor cell lines.
Topics: Aminoglutethimide; Animals; Azasteroids; Breast Neoplasms; Cell Cycle; Cell Line; Danazol; Dexamethasone; Dihydrotestosterone; Estradiol; Flutamide; Humans; Pancreatic Neoplasms; Progesterone; Rats; Receptors, Androgen; Receptors, Estrogen; Tamoxifen | 1986 |
Newer methods of hormonal therapy for prostate cancer.
Topics: Adenocarcinoma; Aminoglutethimide; Androgen Antagonists; Bone Neoplasms; Buserelin; Flutamide; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Male; Megestrol; Megestrol Acetate; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms | 1984 |
Surprising activity of flutamide withdrawal, when combined with aminoglutethimide, in treatment of "hormone-refractory" prostate cancer.
Topics: Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Flutamide; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms; Time Factors; Treatment Outcome | 1994 |
Regulation by gonadotropins of the messenger ribonucleic acid for P450 side-chain cleavage, P450(17) alpha-hydroxylase/C17,20-lyase, and 3 beta-hydroxysteroid dehydrogenase in cultured pig Leydig cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Aminoglutethimide; Animals; Aromatase Inhibitors; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Flutamide; Gene Expression Regulation, Enzymologic; Gonadotropins; Kinetics; Leydig Cells; Luteinizing Hormone; Male; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Swine; Testosterone | 1996 |
Flutamide withdrawal and concomitant initiation of aminoglutethimide in patients with hormone refractory prostate cancer.
Topics: Aged; Aminoglutethimide; Androgen Antagonists; Antineoplastic Agents, Hormonal; Drug Resistance, Neoplasm; Flutamide; Humans; Male; Middle Aged; Prostatic Neoplasms | 1996 |
Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: a possible androgenic bone protective effects induced by exemestane.
Topics: Alkaline Phosphatase; Aminoglutethimide; Androstadienes; Aromatase Inhibitors; Base Sequence; Cell Line; Cell Proliferation; DNA Primers; Estradiol; Flutamide; Gene Expression; Humans; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteoclasts; Osteoporosis; Receptors, Androgen; RNA, Messenger; Testosterone; Testosterone Congeners | 2007 |
Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery.
Topics: 4-Aminopyridine; Adenine; Aminoglutethimide; Androgen Receptor Antagonists; Animals; Aromatase Inhibitors; Barium Compounds; Basilar Artery; Calcium Channel Blockers; Calcium Channels; Chlorides; Cycloheximide; Dactinomycin; Dogs; Enzyme Inhibitors; Flutamide; In Vitro Techniques; Male; Nifedipine; Nucleic Acid Synthesis Inhibitors; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Protein Synthesis Inhibitors; Quinoxalines; Testosterone; Vasodilation; Vasodilator Agents | 2011 |