aminoglutethimide and fluorouracil

aminoglutethimide has been researched along with fluorouracil in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199010 (47.62)18.7374
1990's1 (4.76)18.2507
2000's5 (23.81)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Barnes, SG; Bartholomew, MJ; Dixon, RH; Givant, EM; Harvey, HA; Lipton, A; Nadjafi, C; Santen, RJ; Stryker, JA; Walker, BK1
Boogerd, W; Bruning, PF; Kröger, R; Somers, R; van der Sande, JJ1
Bartholomew, M; Boucher, A; Caplan, R; Gordon, R; Harvey, H; Lipton, A; Manni, A; Santen, R; Simmonds, M; White-Hershey, D1
Boucher, AE; Drago, J; Gordon, R; Harvey, H; Lipton, A; Manni, A; Rohner, T; Santen, RJ; Simmonds, M; Wettlaufer, J1
Dabag, S; Rieche, K; Scharlau, L1
Clarysse, A; Ferrazzi, E; Heuson, JC; Julien, JP; Paridaens, R; Rotmensz, N; Van der Wijst, JB1
Graziottin, A; Marchetti, M; Onnis, A; Velasco, M1
Mattheiem, W; Mouridsen, HT; Palshof, T; Paridaens, RJ; Rotmensz, N; Sylvester, RJ1
Holland, JF; Perlow, LS1
Bezwoda, WR; Browde, S; Derman, DP; Goss, G; Lange, M1
Costanza, ME1
Branković-Magić, MV; Mitrovic, LB; Nesković-Konstantinović, ZB; Nikolić-Vukosavljević, DB; Spuzić, I1
Dietze, O; Filipits, M; Gnant, MF; Greil, R; Grill, R; Huynh, A; Jakesz, R; Kwasny, W; Lax, S; Lehnert, M; Rudas, M; Schippinger, W; Singer, C; Stierer, M; Stiglbauer, W1

Reviews

2 review(s) available for aminoglutethimide and fluorouracil

ArticleYear
Introduction to chemotherapy and antineoplastic pharmacology in breast cancer.
    European journal of gynaecological oncology, 1982, Volume: 3, Issue:1

    Topics: Aminoglutethimide; Androgens; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Estrogen Antagonists; Estrogens; Female; Fluorouracil; Glucocorticoids; Humans; Male; Methotrexate; Palliative Care; Progestins; Receptors, Estrogen; Receptors, Progesterone

1982
Chemotherapy of breast cancer.
    Medical oncology and tumor pharmacotherapy, 1984, Volume: 1, Issue:3

    Topics: Adrenalectomy; Alkylating Agents; Aminoglutethimide; Androgens; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Estrogens; Female; Fluorouracil; Humans; Immunotherapy; Methotrexate; Naphthacenes; Pituitary Hormone-Releasing Hormones; Progestins; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Vinca Alkaloids

1984

Trials

7 trial(s) available for aminoglutethimide and fluorouracil

ArticleYear
FAM chemotherapy +/- aminoglutethimide in the treatment of pancreatic carcinoma.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1990, Volume: 16, Issue:1

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Drug Evaluation; Fluorouracil; Humans; Hydrocortisone; Mitomycin; Mitomycins; Pancreatic Neoplasms; Prospective Studies; Random Allocation; Survival Rate

1990
Androgen priming and chemotherapy in advanced prostate cancer: evaluation of determinants of clinical outcome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:9

    Topics: Acid Phosphatase; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Fluorouracil; Fluoxymesterone; Follow-Up Studies; Humans; Hydrocortisone; Male; Prostatic Neoplasms; Random Allocation; Testosterone; Time Factors

1988
Androgen depletion and repletion as a means of potentiating the effect of cytotoxic chemotherapy in advanced prostate cancer.
    Journal of steroid biochemistry, 1987, Volume: 27, Issue:1-3

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Synergism; Fluorouracil; Fluoxymesterone; Humans; Hydrocortisone; Male; Methotrexate; Orchiectomy; Prostatic Neoplasms; Random Allocation; Spinal Cord Compression

1987
Aminoglutethimide and estrogenic stimulation before chemotherapy for treatment of advanced breast cancer. Preliminary results of a phase II study conducted by the E.O.R.T.C. Breast Cancer Cooperative Group.
    Journal of steroid biochemistry, 1985, Volume: 23, Issue:6B

    Topics: Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Evaluation; Estrogens; Ethinyl Estradiol; Fluorouracil; Humans; Hydrocortisone; Middle Aged; Prognosis; Time Factors

1985
Currently active protocols in the EORTC Breast Cancer Cooperative Group.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1984, Volume: 91

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Receptors, Estrogen; Tamoxifen

1984
Content of epidermal growth factor receptor in metastatic breast cancer: its role in endocrine sensitivity prediction.
    Neoplasma, 2000, Volume: 47, Issue:2

    Topics: Adult; Aminoglutethimide; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; ErbB Receptors; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Ovariectomy; Predictive Value of Tests; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tamoxifen; Treatment Outcome

2000
Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Mar-15, Volume: 14, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclin D1; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Goserelin; Humans; Methotrexate; Middle Aged; Prognosis; Receptors, Cytoplasmic and Nuclear; Recurrence; Tamoxifen; Treatment Outcome

2008

Other Studies

12 other study(ies) available for aminoglutethimide and fluorouracil

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effective systemic therapy for spinal epidural metastases from breast carcinoma.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:1

    Topics: Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Epidural Neoplasms; Female; Fluorouracil; Humans; Hydrocortisone; Methotrexate; Middle Aged; Radiography

1989
[Combination of aminoglutethimide and polychemotherapy for the treatment of predominant bone metastasis in breast cancer].
    Deutsche medizinische Wochenschrift (1946), 1986, Nov-07, Volume: 111, Issue:45

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Vinblastine; Vincristine

1986
Treatment of advanced breast cancer with aminoglutethimide--response after previous tamoxifen treatment.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Sep-08, Volume: 66, Issue:10

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Fluoxymesterone; Humans; Menopause; Methotrexate; Tamoxifen; Time Factors

1984
The medical management of breast cancer.
    Clinical obstetrics and gynecology, 1982, Volume: 25, Issue:2

    Topics: Adjuvants, Pharmaceutic; Adult; Aminoglutethimide; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hypophysectomy; Melphalan; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Receptors, Estrogen; Tamoxifen

1982