aminoglutethimide has been researched along with fadrozole in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.89) | 18.7374 |
| 1990's | 20 (55.56) | 18.2507 |
| 2000's | 8 (22.22) | 29.6817 |
| 2010's | 2 (5.56) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Bhatnager, A; Browne, LJ; Gude, C; Rodriguez, H; Steele, RE | 1 |
| Cole, PA; Robinson, CH | 1 |
| Bartz, U; Bayer, H; Grün, G; Hartmann, RW; Mitrenga, M; Sergejew, T | 1 |
| Belluti, F; Bisi, A; Cavalli, A; Gobbi, S; Hartmann, RW; Palusczak, A; Palzer, M; Rampa, A; Recanatini, M; Valenti, P | 1 |
| Muftuoglu, Y; Mustata, G | 1 |
| Egbuta, C; Ghosh, D; Lo, J | 1 |
| Chen, JZ; Khan, MZI; Nazli, A; Uzair, M | 1 |
| Bogart, MH; Lance, VA | 1 |
| Borja, J; Pérez, N | 1 |
| Dowsett, M; Mehta, A; Newton, CJ | 1 |
| Dowsett, M; Lønning, PE; Powles, TJ | 1 |
| Santen, RJ | 1 |
| Dowsett, M | 1 |
| Bhatnagar, AS; Häusler, A; Krähenbühl, C; Monnet, G; Schenkel, L | 1 |
| Miller, WR | 1 |
| Bhatnagar, AS; Borer, C; Häusler, A; Monnet, G | 1 |
| Bhatnagar, AS; Matter, A; Schieweck, K | 1 |
| Nicholls, PJ; Shaw, MA; Smith, HJ | 1 |
| Manni, A | 1 |
| Cam, LL; Chen, S; Korzekwa, KR; Laughton, CA; Zhou, D | 1 |
| Bhatnagar, AS; King, EJ; Purba, HS; Richert, P | 1 |
| Cherkaoui, S; Faupel, M; Francotte, E | 1 |
| Kanno, H; Kim, T; Kitawaki, J; Noguchi, T; Okada, H; Yamamoto, T | 1 |
| Höffken, K | 1 |
| Grün, GL; Hartmann, RW; Ledergerber, D; Sergejew, T; Wächter, GA | 1 |
| Boyle, T; Dukes, M; Edwards, PN; Large, M; Smith, IK | 1 |
| Ahmed, S; Davis, PJ; Owen, CP | 1 |
| Durgam, VR; Tekmal, RR | 1 |
| Smith, IE | 1 |
| Auvray, P; Bichat, F; Genne, P | 1 |
| de Crémoux, P | 1 |
| Buzdar, AU | 1 |
| King, HR; Lee, PS; Pankhurst, NW | 1 |
| Giesy, JP; Hecker, M; Higley, EB; Jones, PD; Murphy, MB; Newsted, JL; Wu, R | 1 |
| Ioannidis, JP; Mauri, D; Pavlidis, N; Polyzos, NP | 1 |
| Dutta, U; Pant, K | 1 |
17 review(s) available for aminoglutethimide and fadrozole
| Article | Year |
|---|---|
Mechanism and inhibition of cytochrome P-450 aromatase.
Topics: Affinity Labels; Aromatase; Aromatase Inhibitors; Binding, Competitive; Humans; Molecular Structure; Photochemistry | 1990 |
Recent Progress in the Discovery of Next Generation Inhibitors of Aromatase from the Structure-Function Perspective.
Topics: Aromatase; Aromatase Inhibitors; Catalytic Domain; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2016 |
An overview on Estrogen receptors signaling and its ligands in breast cancer.
Topics: Breast Neoplasms; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Ligands; Male; Receptors, Estrogen | 2022 |
Aromatase inhibitors: clinical pharmacology and therapeutic implications in breast cancer.
Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Letrozole; Nitriles; Triazoles | 1992 |
Postmenopausal estrogen synthesis and metabolism: alterations caused by aromatase inhibitors used for the treatment of breast cancer.
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Fadrozole; Female; Humans; Imidazoles; Menopause; Nitriles | 1990 |
Recent progress in development of aromatase inhibitors.
Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Humans; Imidazoles; Nitriles | 1990 |
Clinical development of aromatase inhibitors for the treatment of breast and prostate cancer.
Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Estrogen Antagonists; Fadrozole; Humans; Imidazoles; Nitriles | 1990 |
Aromatase inhibitors in the treatment of advanced breast cancer.
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Neoplasms, Hormone-Dependent; Nitriles | 1989 |
Aminoglutethimide and ketoconazole: historical perspectives and future prospects.
Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Ketoconazole; Male; Nitriles; Prostatic Neoplasms | 1988 |
Clinical use of aromatase inhibitors in the treatment of breast cancers.
Topics: Aminoglutethimide; Animals; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Letrozole; Nitriles; Rats; Triazoles | 1993 |
Experience with aromatase inhibitors in the treatment of advanced breast cancer.
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Forecasting; Humans | 1993 |
Aromatase inhibitors: a dose-response effect?
Topics: Aminoglutethimide; Anastrozole; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrogens; Fadrozole; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 1999 |
[Preclinical evaluation of aromatase inhibitors antitumor activity].
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Models, Animal; Nitriles; Rats; Structure-Activity Relationship; Triazoles | 2000 |
[Aromatase inhibitors: pharmacological aspects].
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles | 2000 |
A summary of second-line randomized studies of aromatase inhibitors.
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Drug Tolerance; Enzyme Inhibitors; Estrogen Receptor Modulators; Fadrozole; Female; Humans; Letrozole; Megestrol Acetate; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2001 |
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis.
Topics: Adult; Aged; Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles | 2006 |
Aromatase inhibitors: past, present and future in breast cancer therapy.
Topics: Aminoglutethimide; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles | 2008 |
19 other study(ies) available for aminoglutethimide and fadrozole
| Article | Year |
|---|---|
Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease.
Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Chemical Phenomena; Chemistry; Estrogen Antagonists; Fadrozole; Female; Humans; Imidazoles; Nitriles; Rats; Structure-Activity Relationship | 1991 |
Pyridyl-substituted tetrahydrocyclopropa[a]naphthalenes: highly active and selective inhibitors of P450 arom.
Topics: Adrenal Glands; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cattle; Female; Humans; Liver; Male; Mammary Neoplasms, Experimental; Naphthalenes; Ovary; Placenta; Pyridines; Rats; Testis | 1995 |
A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase.
Topics: Aromatase Inhibitors; Chromones; Drug Design; Enzyme Inhibitors; Humans; In Vitro Techniques; Male; Microsomes; Models, Molecular; Placenta; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Testis; Xanthenes; Xanthones | 2001 |
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Simulation; Drug Design; Female; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship | 2010 |
Disruption of ovarian development in alligator embryos treated with an aromatase inhibitor.
Topics: Alligators and Crocodiles; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Cyproterone; Cyproterone Acetate; Estradiol; Fadrozole; Female; Imidazoles; Male; Nitriles; Ovary; Tamoxifen; Testis | 1992 |
The effect of the aromatase inhibitor, rogletimide (pyridoglutethimide), on guinea pig adrenal cell steroidogenesis and placental microsomal aromatase activity: comparison with aminoglutethimide and CGS 16949A.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Aromatase; Aromatase Inhibitors; Fadrozole; Female; Guinea Pigs; Hydrocortisone; Imidazoles; In Vitro Techniques; Kinetics; Male; Microsomes; Nitriles; Placenta; Pregnancy; Steroids | 1991 |
An in vitro method to determine the selective inhibition of estrogen biosynthesis by aromatase inhibitors.
Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Cricetinae; Estrogen Antagonists; Estrogens; Estrus; Fadrozole; Female; Imidazoles; Kinetics; Luteinizing Hormone; Mesocricetus; Nitriles; Ovary; Progesterone; Testolactone; Testosterone | 1989 |
Evidence that corticosterone is not an obligatory intermediate in aldosterone biosynthesis in the rat adrenal.
Topics: Adrenal Glands; Aldosterone; Aminoglutethimide; Animals; Aromatase Inhibitors; Corticosterone; Cosyntropin; Delayed-Action Preparations; Desoxycorticosterone; Fadrozole; Imidazoles; In Vitro Techniques; Male; Nitriles; Rats; Rats, Inbred Strains | 1989 |
CGS 16949A, a new nonsteroidal aromatase inhibitor: effects on hormone-dependent and -independent tumors in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Animals; Aromatase Inhibitors; Body Weight; Cell Line; Drug Screening Assays, Antitumor; Fadrozole; Female; Imidazoles; Mammary Neoplasms, Experimental; Nitriles; Rats; Tamoxifen | 1988 |
Mutagenesis study at a postulated hydrophobic region near the active site of aromatase cytochrome P450.
Topics: Amino Acid Sequence; Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Computer Simulation; DNA Mutational Analysis; Dose-Response Relationship, Drug; Fadrozole; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1994 |
Effect of aromatase inhibitors on estrogen 2-hydroxylase in rat liver.
Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Fadrozole; Female; Ketoconazole; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Substrate Specificity | 1994 |
Separation of the enantiomers of some racemic nonsteroidal aromatase inhibitors and barbiturates by capillary electrophoresis.
Topics: Aminoglutethimide; Aromatase Inhibitors; Barbiturates; Cyclodextrins; Electrophoresis; Fadrozole; Glutethimide; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 1993 |
Growth suppression of MCF-7 human breast cancer cells by aromatase inhibitors: a new system for aromatase inhibitor screening.
Topics: Aminoglutethimide; Androstenedione; Androstenols; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Fadrozole; Female; Humans; Kinetics; Tumor Cells, Cultured | 1993 |
Tetrahydronaphthalenes: influence of heterocyclic substituents on inhibition of steroid enzymes P450 arom and P450 17.
Topics: Aminoglutethimide; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Fadrozole; Female; Humans; Indicators and Reagents; Kinetics; Male; Molecular Structure; Naphthalenes; Placenta; Rats; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Testis; Thromboxane-A Synthase | 1996 |
The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033)--a potent, selective aromatase inhibitor.
Topics: Adrenal Glands; Aminoglutethimide; Anastrozole; Androstenedione; Animals; Aromatase Inhibitors; Cortodoxone; Enzyme Inhibitors; Fadrozole; Female; Hormones; Humans; Macaca nemestrina; Male; Metyrapone; Nitriles; Organ Size; Potassium; Prostate; Rats; Rats, Wistar; Seminal Vesicles; Sodium; Triazoles; Uterus | 1996 |
Molecular modelling study of the binding of inhibitors of aromatase to the cytochrome P-450 heme.
Topics: Aminoglutethimide; Aromatase; Aromatase Inhibitors; Binding Sites; Computer Simulation; Fadrozole; Heme; Ligands; Models, Molecular; Molecular Structure; Pyridines; Stereoisomerism; Steroids; Structure-Activity Relationship | 1996 |
A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Analysis of Variance; Anastrozole; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Fadrozole; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Ovariectomy; Postmenopause; Triazoles; Tumor Cells, Cultured | 1997 |
Effects of aromatase inhibitors on in vitro steroidogenesis by Atlantic salmon (Salmo salar) gonadal and brain tissue.
Topics: Aminoglutethimide; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Brain; Estradiol; Fadrozole; Female; Miconazole; Ovarian Follicle; Salmo salar; Testosterone | 2006 |
Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production.
Topics: Adrenal Cortex; Adrenocortical Carcinoma; Aminoglutethimide; Antifungal Agents; Aromatase Inhibitors; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Endocrine Disruptors; Enzyme-Linked Immunosorbent Assay; Estradiol; Fadrozole; Fungicides, Industrial; Gonadal Steroid Hormones; Humans; Imidazoles; Ketoconazole; Oxazoles; Progesterone; Testosterone | 2006 |