aminoglutethimide and desoxycorticosterone

aminoglutethimide has been researched along with desoxycorticosterone in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199017 (77.27)18.7374
1990's3 (13.64)18.2507
2000's1 (4.55)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berger, ML; Hahner, S; Hammerschmidt, F; Peric-Simov, B; Schirbel, A; Zolle, IM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Simpson, ER; Williams-Smith, DL1
Cammack, R; Williams-Smith, DL1
Sawhney, RS; Sharma, RK1
Dunn, AJ; Leibmann, S1
Aguilera, G; Catt, KJ1
Auzeby, A; Bogdan, A; Dommergues, JP; Touitou, Y1
Island, DP; Liddle, GW; McKenna, TJ; Nicholson, WE1
Bhatnagar, AS; Borer, C; Häusler, A; Monnet, G1
Ghersi-Egea, JF; Minn, A; Siest, G; Walther, B1
Ikeda, M; Katagiri, M; Koshida, H; Miyamori, I; Nagai, K; Suhara, K; Takeda, R1
Camacho, AM; Hagen, AA; Trouy, RL; Wilroy, RS1
Johnston, GG; Krisle, JR; Troop, RC1
Bartová, A; Birmingham, MK; Tibagong, M1
Diedrichsen, G; Lommer, D1
Dawson, K; Genest, J; Kuchel, O; Mancheno-Rico, E; Nowaczynski, W; Sasaki, C; Seth, KK1
Jeffries, CD; Wilkins, J1
Morris, B; Morris, R1
De Villiers, EP; Swart, AC; Swart, P; Todres, PC; van der Merwe, KJ1
Jefcoate, CR; McNamara, BC; Yamazaki, T1
Crabbe, JC; Keith, LD; Roberts, AJ1

Other Studies

22 other study(ies) available for aminoglutethimide and desoxycorticosterone

ArticleYear
New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Adrenal Cortex; Animals; Binding Sites; Etomidate; Humans; Hydroxylation; Iodine Radioisotopes; Kinetics; Male; Molecular Structure; Rats; Rats, Wistar; Stereoisomerism; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Electron paramagnetic resonance spectra of mitochondrial and microsomal cytochrome P-450 from the rat adrenal.
    Biochimica et biophysica acta, 1976, Oct-13, Volume: 449, Issue:1

    Topics: Adrenal Glands; Aminoglutethimide; Animals; Calcium; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Female; Hydrogen-Ion Concentration; Isocitrates; Metyrapone; Microsomes; Mitochondria; Pregnenolone; Rats; Succinates

1976
Oxidation-reduction potentials of cytochromes P-450 and ferredoxin in the bovine adrenal. Their modification by substrates and inhibitors.
    Biochimica et biophysica acta, 1977, Oct-25, Volume: 499, Issue:3

    Topics: Adrenal Glands; Aminoglutethimide; Animals; Cattle; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Ferredoxins; Hydrogen-Ion Concentration; Hydroxycholesterols; Metyrapone; Microsomes; Mitochondria; Oxidation-Reduction; Potentiometry; Protein Binding

1977
Metabolic regulation of steroidogenesis in isolated adrenal cell. Investigation of the adrenocorticotropic hormone, guanosine 3',5'-monophosphate, and adenosine 3',5'-monophosphate control step.
    Biochemistry, 1978, Jan-24, Volume: 17, Issue:2

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cholesterol; Corticosterone; Cycloheximide; Desoxycorticosterone; Hydroxycholesterols; In Vitro Techniques; Male; Mitochondria; NADP; Nucleotides, Cyclic; Rats

1978
The amnestic effect of protein synthesis inhibitors is not due to the inhibition of adrenal corticosteroidogenesis.
    Behavioral biology, 1977, Volume: 19, Issue:3

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Amnesia; Animals; Anisomycin; Avoidance Learning; Corticosterone; Cycloheximide; Desoxycorticosterone; Dexamethasone; Humans; Male; Mice; Nerve Tissue Proteins; Retention, Psychology; Time Factors

1977
Loci of action of regulators of aldosterone biosynthesis in isolated glomerulosa cells.
    Endocrinology, 1979, Volume: 104, Issue:4

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Corticosterone; Desoxycorticosterone; Dogs; In Vitro Techniques; Potassium; Progesterone; Rats; Spironolactone

1979
Glucocorticoid and mineralocorticoid pathways in two adrenocortical carcinomas: comparison of the effects of o,p'-dichlorodiphenyldichloroethane, aminoglutethimide and 2-p-aminophenyl-2-phenylethylamine in vitro.
    The Journal of endocrinology, 1979, Volume: 82, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adult; Aminoglutethimide; Aniline Compounds; Child; Cortodoxone; Desoxycorticosterone; Female; Glucocorticoids; Humans; In Vitro Techniques; Male; Mineralocorticoids; Mitotane; Phenethylamines; Steroid Hydroxylases

1979
Angiotensin stimulates both early and late steps in aldosterone biosynthesis in isolated bovine glomerulosa cells.
    Journal of steroid biochemistry, 1978, Volume: 9, Issue:10

    Topics: Adrenal Cortex; Aldosterone; Aminoglutethimide; Angiotensins; Animals; Cattle; Corticosterone; Desoxycorticosterone; Hydrocortisone; Kinetics; Pregnenolone

1978
Evidence that corticosterone is not an obligatory intermediate in aldosterone biosynthesis in the rat adrenal.
    Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6

    Topics: Adrenal Glands; Aldosterone; Aminoglutethimide; Animals; Aromatase Inhibitors; Corticosterone; Cosyntropin; Delayed-Action Preparations; Desoxycorticosterone; Fadrozole; Imidazoles; In Vitro Techniques; Male; Nitriles; Rats; Rats, Inbred Strains

1989
Brain mitochondrial cytochrome P-450scc: spectral and catalytic properties.
    Archives of biochemistry and biophysics, 1987, May-01, Volume: 254, Issue:2

    Topics: Aminoglutethimide; Animals; Brain; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Desoxycorticosterone; Male; Mitochondria; NADP; Oxidation-Reduction; Oxidoreductases; Pregnenolone; Rats; Rats, Inbred Strains; Spectrophotometry

1987
Effect of ketoconazole (an imidazole antimycotic agent) and other inhibitors of steroidogenesis on cytochrome P450-catalyzed reactions.
    Journal of steroid biochemistry, 1986, Volume: 24, Issue:1

    Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Aminoglutethimide; Animals; Cattle; Cholesterol; Corticosterone; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Electron Transport; In Vitro Techniques; Ketoconazole; Mitochondria; Pregnenolone; Steroids

1986
Inhibition of adrenal cortical secretion by amino-glutethimide in dogs.
    Endocrinology, 1968, Volume: 83, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Chromatography, Paper; Corticosterone; Dehydroepiandrosterone; Depression, Chemical; Desoxycorticosterone; Dogs; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Pyridones; Veins

1968
Inhibition of adrenal steroidogenesis by glutethimide.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 129, Issue:1

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Body Weight; Cholesterol; Corticosterone; Desoxycorticosterone; Female; Glutethimide; Hydroxyprogesterones; In Vitro Techniques; Methods; Organ Size; Pregnenolone; Rats

1968
Steroid-mediated stimulation of aerobic glycolysis by intact mouse adrenal glands in vitro.
    Endocrinology, 1971, Volume: 89, Issue:5

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aerobiosis; Aminoglutethimide; Analysis of Variance; Animals; Carbon Isotopes; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Fluorescence; Glycolysis; Hydroxyprogesterones; In Vitro Techniques; Lactates; Male; Metyrapone; Mice; Pregnanes; Progesterone; Pyruvates; Spectrophotometry; Ultraviolet Rays

1971
In-vitro corticosteroid synthesis in rat adrenals. II. Evidence for (an) alternative pathway(s) of synthesis.
    Acta endocrinologica. Supplementum, 1973, Volume: 173

    Topics: Acetates; Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Animals; Carbon Isotopes; Cholesterol; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Rats; Triparanol; Tritium

1973
A dissociated effect of amino-glutethimide on the mineralocorticoid secretion in man.
    Metabolism: clinical and experimental, 1973, Volume: 22, Issue:2

    Topics: Adult; Aldosterone; Aminoglutethimide; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Potassium; Pregnanediol; Pregnanetriol; Progesterone; Secretory Rate; Sodium; Tritium

1973
Effect of exogenous steroids and inhibitors of steroidogenesis on endotoxin shock.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 142, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Androstenedione; Animals; Butanones; Corticosterone; Desoxycorticosterone; Endotoxins; Hydrocortisone; Hydroxyprogesterones; Lethal Dose 50; Male; Metyrapone; Mice; Mice, Inbred ICR; Pregnenes; Pregnenolone; Progesterone; Shock, Septic

1973
The effect of exogenous steroids and steroid inhibitors on IgG transmissions in young rats.
    Biology of the neonate, 1980, Volume: 38, Issue:3-4

    Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Corticosterone; Cortisone; Desoxycorticosterone; Hydrocortisone; Immunoglobulin G; Intestine, Small; Maternal Deprivation; Metyrapone; Rats; Succinates

1980
The interaction of biogenic amines with adrenal cytochrome P450-dependent enzymes.
    Biochemical Society transactions, 1993, Volume: 21, Issue:4

    Topics: Adrenal Cortex; Aminoglutethimide; Animals; Biogenic Amines; Cattle; Cell Line; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Isoenzymes; Metanephrine; Microsomes; Pregnenolone; Progesterone; Sheep; Transfection

1993
Competition for electron transfer between cytochromes P450scc and P45011 beta in rat adrenal mitochondria.
    Molecular and cellular endocrinology, 1993, Volume: 95, Issue:1-2

    Topics: Adrenal Cortex; Adrenodoxin; Aminoglutethimide; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cosyntropin; Desoxycorticosterone; Electron Transport; Female; Ferredoxin-NADP Reductase; Isocitrates; Isoenzymes; Metyrapone; Mitochondria; NADP; Oxidation-Reduction; Pregnenolone; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase; Succinates; Succinic Acid

1993
Type I corticosteroid receptors modulate PTZ-induced convulsions of withdrawal seizure prone mice.
    Brain research, 1993, Oct-29, Volume: 626, Issue:1-2

    Topics: Aminoglutethimide; Animals; Desoxycorticosterone; Dexamethasone; Disease Susceptibility; Ethanol; Male; Mice; Pentylenetetrazole; Reaction Time; Receptors, Steroid; Seizures; Substance Withdrawal Syndrome

1993