aminoglutethimide and danazol

aminoglutethimide has been researched along with danazol in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199019 (51.35)18.7374
1990's7 (18.92)18.2507
2000's4 (10.81)29.6817
2010's7 (18.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ashley, SE; Coombes, RC; Ellin, CL; Hardy, JR; Judson, IR; Powles, TJ; Sinnett, HD1
Büchner, T; Hiddemann, W; Koenigsmann, M; Wörmann, B; Zühlsdorf, M1
Fekete, S; Gráf, F; Raposa, T; Várkonyi, J1
Stein, RS1
Büchner, T; Hiddemann, W; Van de Loo, J; Volkenandt, M1
Carlström, K; Pousette, A; Rannevik, G; Sköldefors, H; Theve, NO; Wilking, N1
Büchner, T; Göhde, W; Hiddemann, W; Wörmann, B1
Benz, C; Hollander, C; Miller, B1
Coombes, RC; Easton, D; Goss, PE; Singh, D; Wilkinson, JR; Williams, JC1
Dowsett, M; Jeffcoate, SL; Murray, RM; Pitt, P2
Lutz, D1
Grisold, W; Lutz, D; Mamoli, B; Mokrusa, W; Weber, R1
Achterrath, W; Balleisen, L; Büchner, T; Hiddemann, W; Preusser, P; Urbanitz, D1
Ashley, S; Coombes, RC; Ford, HT; Gazet, JC; Nash, AG; Neville, AM; Powles, TJ1
Ingle, JN1
Carlström, K; Döberl, A; Pousette, A; Rannevik, G; Wilking, N1
Coombes, RC; Dowsett, M; Harris, AL; Jeffcoate, SL; McGarrick, GE; Smith, IE1
Coombes, RC; Dady, P; Ford, HT; Gazet, JC; McCready, VR; Parsons, C; Powles, TJ1
Coombes, RC; Gordon, C; Powles, TJ1
Coombes, RC; Ford, HT; Gazet, JC; Henk, M; Nash, AG; Neville, AM; Powles, TJ; Ratcliffe, WA; Rees, LH1
Stalfelt, AM1
Haase, D; Hehlmann, R; Hild, F; Lengfelder, E; Simon, M1
Dengler, R; Emmerich, B; Walther, JU1
Busch, R; Dengler, R; Eger, G; Emmerich, B; Münstermann, U; Plewan, A1
Diehl, V; Dimski, T; Lathan, B; Pantke, B; Schinköthe, T; Staib, P; Voliotis, D; Wiedenmann, S1
Goetz, M; Heussel, H; Hiddemann, W; Schiel, X; Steinmetz, T; Weiss, M1
Haferlach, C; Haferlach, T; Schnittger, S; Weisser, M1
Aul, C; Balleisen, L; Beelen, D; Berdel, WE; Braess, J; Büchner, T; Eimermacher, H; Gale, RP; Giagounidis, A; Görlich, D; Grüneisen, A; Haferlach, C; Haferlach, T; Hehlmann, R; Heinecke, A; Hiddemann, W; Kern, W; Köpcke, W; Krug, U; Lengfelder, E; Ludwig, WD; Maschmeyer, G; Müller-Tidow, C; Rasche, H; Reichle, A; Sauerland, MC; Schliemann, C; Schnittger, S; Serve, H; Spiekermann, K; Staib, P; Stelljes, M; Thiel, E; Wörmann, BJ1

Reviews

1 review(s) available for aminoglutethimide and danazol

ArticleYear
Advances in the therapy of acute nonlymphocytic leukemia.
    The American journal of the medical sciences, 1989, Volume: 297, Issue:1

    Topics: Aminoglutethimide; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Danazol; Humans; Leukemia, Myeloid, Acute; Tamoxifen

1989

Trials

8 trial(s) available for aminoglutethimide and danazol

ArticleYear
Antagonism of aminoglutethimide and danazol in the suppression of serum free oestradiol in breast cancer patients.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:9

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Estradiol; Female; Humans; Middle Aged; Pregnadienes; Sex Hormone-Binding Globulin

1985
Treatment of disseminated breast cancer with tamoxifen, aminoglutethimide, hydrocortisone, and danazol, used in combination or sequentially.
    Lancet (London, England), 1984, Jun-23, Volume: 1, Issue:8391

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Danazol; Female; Humans; Hydrocortisone; Menopause; Receptors, Estrogen; Tamoxifen

1984
Additive hormonal therapy in women with advanced breast cancer.
    Cancer, 1984, Feb-01, Volume: 53, Issue:3 Suppl

    Topics: Aminoglutethimide; Androgens; Breast Neoplasms; Clinical Trials as Topic; Danazol; Drug Therapy, Combination; Estrogens; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Hypophysectomy; Medroxyprogesterone; Medroxyprogesterone Acetate; Menopause; Random Allocation; Tamoxifen

1984
Clinical trial of multiple endocrine therapy for metastatic and locally advanced breast cancer with tamoxifen-aminoglutethimide-danazol compared to tamoxifen used alone.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aminoglutethimide; Breast Neoplasms; Clinical Trials as Topic; Danazol; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Pregnadienes; Probability; Random Allocation; Tamoxifen

1982
Quality of life during induction treatment of acute myeloid leukaemia. A comparison of three intensive chemotherapy regimens using three instruments for quality of life assessment.
    Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Danazol; Female; Humans; Interviews as Topic; Karnofsky Performance Status; Leukemia, Myeloid; Longitudinal Studies; Male; Methods; Middle Aged; Prospective Studies; Quality of Life; Randomized Controlled Trials as Topic; Surveys and Questionnaires; Tamoxifen

1994
Prognosis in adult AML is precisely predicted by the DISC-assay using the chemosensitivity-index Ci.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Adult; Aminoglutethimide; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cell Survival; Cytarabine; Danazol; Drug Screening Assays, Antitumor; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Predictive Value of Tests; Prognosis; Prospective Studies; Regression Analysis; Remission Induction; Survival Analysis; Tamoxifen; Vidarabine

1999
Elevation of soluble tumor necrosis factor receptor II in non-febrile patients with acute myeloid leukemia.
    European journal of medical research, 2002, Nov-25, Volume: 7, Issue:11

    Topics: Adult; Aged; Aminoglutethimide; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Danazol; Etanercept; Female; Fever; Humans; Immunoglobulin G; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Neutropenia; Prospective Studies; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Tamoxifen

2002
Increasing intensity of therapies assigned at diagnosis does not improve survival of adults with acute myeloid leukemia.
    Leukemia, 2016, Volume: 30, Issue:6

    Topics: Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Danazol; Disease-Free Survival; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Stem Cell Transplantation; Survival Rate; Tamoxifen; Transplantation, Autologous; Treatment Outcome; Young Adult

2016

Other Studies

28 other study(ies) available for aminoglutethimide and danazol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Combination of tamoxifen, aminoglutethimide, danazol and medroxyprogesterone acetate in advanced breast cancer.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:7

    Topics: Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Female; Humans; Medroxyprogesterone; Middle Aged; Neoplasm Metastasis; Tamoxifen

1990
Changing response of clonogenic myeloid leukemia blasts to granulocyte-macrophage colony-stimulating factor (GM-CSF) during anti-leukemic therapy--a case report on the basis of a clinical phase II trial.
    Leukemia research, 1990, Volume: 14, Issue:4

    Topics: Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colony-Stimulating Factors; Danazol; DNA, Neoplasm; Drug Evaluation; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Tamoxifen

1990
Cytochemical maturation index for the prognostication of adult acute nonlymphocytic leukaemia.
    Folia haematologica (Leipzig, Germany : 1928), 1989, Volume: 116, Issue:1

    Topics: Adult; Age Factors; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Cell Differentiation; Cell Survival; Danazol; Esterases; Humans; Leukemia, Myeloid, Acute; Middle Aged; Peroxidases; Prognosis; Remission Induction; Tamoxifen

1989
Acute leukaemia during pregnancy.
    Lancet (London, England), 1987, Dec-26, Volume: 2, Issue:8574

    Topics: Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Danazol; Female; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Tamoxifen

1987
Endocrine treatment of breast cancer: effects upon intratumoral estrone sulfate metabolism and peripheral steroid levels.
    Breast cancer research and treatment, 1986, Volume: 7 Suppl

    Topics: Aminoglutethimide; Breast Neoplasms; Danazol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Administration Schedule; Estrogens; Estrone; Female; Humans; Pregnadienes; Sex Hormone-Binding Globulin; Tamoxifen

1986
DNA aneuploidies in adult patients with acute myeloid leukemia. Incidence and relation to patient characteristics and morphologic subtypes.
    Cancer, 1986, Jun-01, Volume: 57, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Aminoglutethimide; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Danazol; Flow Cytometry; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Leukocyte Count; Middle Aged; Preleukemia; Tamoxifen

1986
Endocrine-responsive pancreatic carcinoma: steroid binding and cytotoxicity studies in human tumor cell lines.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Aminoglutethimide; Animals; Azasteroids; Breast Neoplasms; Cell Cycle; Cell Line; Danazol; Dexamethasone; Dihydrotestosterone; Estradiol; Flutamide; Humans; Pancreatic Neoplasms; Progesterone; Rats; Receptors, Androgen; Receptors, Estrogen; Tamoxifen

1986
Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Dihydrotestosterone; Female; Humans; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Ovariectomy; Rats; Tamoxifen

1986
Biochemical basis for the antagonism between aminoglutethimide and danazol in the endocrine treatment of breast cancer.
    Annals of clinical biochemistry, 1986, Volume: 23 ( Pt 3)

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Estradiol; Female; Humans; Immunoassay; Sex Hormone-Binding Globulin

1986
[Various induction therapies in older patients with acute myeloid leukemias].
    Wiener klinische Wochenschrift, 1985, Feb-01, Volume: 97, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Danazol; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Tamoxifen

1985
[Acute myelomonocytic and monoblastic leukemia with polyradicular symptoms].
    Wiener klinische Wochenschrift, 1985, Aug-30, Volume: 97, Issue:16

    Topics: Abducens Nerve; Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebral Hemorrhage; Cerebrospinal Fluid; Cranial Nerve Diseases; Cytarabine; Danazol; Demyelinating Diseases; Facial Paralysis; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Meningism; Methotrexate; Middle Aged; Spinal Nerve Roots; Tamoxifen

1985
[AMSA/etoposide (VP 16-213). A phase I/II study in refractory acute myeloid leukemia].
    Onkologie, 1985, Volume: 8, Issue:3

    Topics: Aminoacridines; Aminoglutethimide; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Danazol; Drug Evaluation; Drug Resistance; Etoposide; Humans; Leukemia, Myeloid, Acute; Tamoxifen

1985
Inhibition of steroid sulfatase activity by danazol.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 123

    Topics: Aminoglutethimide; Breast Neoplasms; Carcinoma; Culture Techniques; Danazol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estrogen Antagonists; Estrone; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Pregnadienes; Tamoxifen

1984
Prognostic significance of serum prolactin levels in advanced breast cancer.
    British journal of cancer, 1983, Volume: 47, Issue:6

    Topics: Aminoglutethimide; Breast Neoplasms; Danazol; Drug Therapy, Combination; Female; Humans; Menopause; Prognosis; Prolactin; Tamoxifen

1983
Assessment of response of bone metastases to systemic treatment in patients with breast cancer.
    Cancer, 1983, Aug-15, Volume: 52, Issue:4

    Topics: Alkaline Phosphatase; Aminoglutethimide; Antineoplastic Agents; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Calcium; Creatinine; Danazol; Doxorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyproline; Radiography; Tamoxifen; Time Factors; Vincristine

1983
Tamoxifen, aminoglutethimide and danazol: effect of therapy on hormones in post-menopausal patients with breast cancer.
    British journal of cancer, 1982, Volume: 46, Issue:1

    Topics: Aminoglutethimide; Androgens; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Drug Therapy, Combination; Estradiol; Female; Gonadotropins, Pituitary; Hormones; Humans; Menopause; Pregnadienes; Tamoxifen

1982
[Complete remission in acute promyelocytic leukemia. The advantages of all-trans-retinoic acid compared to conventional chemotherapy].
    Deutsche medizinische Wochenschrift (1946), 1994, Aug-26, Volume: 119, Issue:34-35

    Topics: Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Danazol; Drug Evaluation; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Tamoxifen; Time Factors; Tretinoin

1994
Trisomy 21 as the sole clonal aberration in a patient with acute myelomonocytic leukemia with abnormal bone marrow eosinophils and extramedullary involvement.
    Annals of hematology, 1994, Volume: 68, Issue:2

    Topics: Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Danazol; Down Syndrome; Eosinophils; Humans; Leukemia, Myelomonocytic, Acute; Male; Tamoxifen

1994
Urinary excretion of proteolyzed alpha1-antitrypsin: specificity, quantitation, and relation to therapy response in patients with acute myeloid leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:2

    Topics: Adult; Aged; alpha 1-Antitrypsin; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blast Crisis; Bleomycin; Bone Marrow; Cyclophosphamide; Dacarbazine; Danazol; Disease-Free Survival; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nimustine; Peptide Fragments; Prednisone; Probability; Procarbazine; Prognosis; Proteinuria; Recurrence; Remission Induction; Reproducibility of Results; Tamoxifen; Time Factors; Vincristine

1995
Advanced age and high initial WBC influence the outcome of inv(3) (q21q26)/t(3;3) (q21;q26) positive AML.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:11

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 3; Cohort Studies; Cytarabine; Danazol; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Karyotyping; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Analysis; Tamoxifen; Translocation, Genetic

2007