aminoglutethimide and androstenedione

aminoglutethimide has been researched along with androstenedione in 121 studies

Research

Studies (121)

Timeframe	Studies, this research(%)	All Research%
pre-1990	62 (51.24)	18.7374
1990's	47 (38.84)	18.2507
2000's	11 (9.09)	29.6817
2010's	1 (0.83)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cole, PA; Robinson, CH	1
Bartz, U; Bayer, H; Grün, G; Hartmann, RW; Mitrenga, M; Sergejew, T	1
Bayer, H; Grün, G; Hartmann, RW	1
Barmade, MA; Murumkar, PR; Tamboli, RS; Yadav, MR	1
Harvey, H; Lipton, A; Samojlik, E; Santen, RJ; Veldhuis, J; Wells, SA	1
Audi, L; Collu, R; Ducharme, JR; Jéquier, JC; Laurin, P; Morera, AM; Saez, J	1
Samojlik, E; Santen, RJ	2
Harvey, H; Kendall, J; Lipton, A; Ruby, EB; Samojlik, E; Santen, RJ; Wells, SA	1
Davis, B; Ruby, E; Samojlik, E; Santen, RJ; Santner, S; Veldhuis, J	1
Beyer, C; Larsson, K; Morali, G	1
Brown, PW; Lawrence, W; Newsome, HH; Terz, JJ	1
deAsis, DN; Samaan, NA	1
Dilley, WG; Haagensen, DE; Harvey, H; Lipton, A; Ruby, EJ; Santen, RJ; Wells, SA	1
Samojlik, E; Santen, RJ; Wells, SA	1
Ahrén, K; Bauminger, S; Collins, WP; Lieberman, ME; Lindner, HR; Tsafriri, A	1
Beyer, C; Larsson, K; Moralí, G; Naftolin, F	1
Ahrén, K; Dekel, N; Hillensjö, T	1
Ahmadi, M; Nazareth, W; Nicholls, PJ; Smith, HJ; Whomsley, R	1
Bogart, MH; Lance, VA	1
Borja, J; Pérez, N	1
Hisamatsu, K; Nomura, Y; Tashiro, H	1
Dowsett, M; Ekse, D; Jacobs, S; Johannessen, DC; Jones, A; Lønning, PE; McNeil, F; Powles, TJ	1
Cantwell, BM; Dowsett, M; Harris, AL; Mehta, A	1
Dowsett, M; Griggs, L; Haynes, B; Jacobs, S; Lønning, PE	1
Bellora, MG; Bergamino, T; Ciancio, A; Ferrero, A; Sismondi, P; Zola, P	1
Anderson, ED; Anderson, TJ; Chetty, U; Forrest, AP; Hawkins, RA; Leonard, RC	1
Chen, SA; Pompon, D; Zhou, DJ	2
Dowsett, M; Lønning, PE; Powles, TJ	1
Distler, W; von Matthiessen, H	1
Santen, RJ	1
Dowsett, M	2
Briatico, G; di Salle, E; Giudici, D; Ornati, G	1
Jarman, M; Laughton, CA; McCague, R; McKenna, R; Neidle, S; Rowlands, MG	1
Dauvois, S; Labrie, F	1
Bhatnagar, AS; Häusler, A; Krähenbühl, C; Monnet, G; Schenkel, L	1
Anderson, ED; Chetty, U; Forrest, AP; Hawkins, RA; Levack, PA	1
Miller, WR	1
Bonfrer, JM; Bruning, PF; de Jong-Bakker, M; Hart, AA; Moolenaar, AJ; Nooijen, WJ; van der Linden, E	1
Manni, A; Santen, RJ	1
Armstrong, DT; Glasier, MA; Khalil, MW; Lang, T; Morley, P	1
Cantwell, BM; Dowsett, M; Harris, AL; Hill, M; Jeffcoate, SL; Smith, IE; Stuart-Harris, R	1
Cantwell, BM; Dowsett, M; Farndon, J; Harris, AL; Needham, G; Sainsbury, JR; Wilson, R	1
Alexieva-Figusch, J; de Jong, FH; Klign, JG; Lamberts, WJ; van Gilse, HA	1
D'Souza, A; Donaldson, A; Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE; Stuart-Harris, R	1
Payne, AH; Rani, CS	1
Brodie, AM; Santen, RJ	1
Dowsett, M; Jeffcoate, SL; Malone, P; Ponder, BA; Shearer, RJ	1
Ayub, M; Levell, MJ	1
Okada, H; Urabe, M; Yamamoto, T	1
Miller, WR; O'Neill, J	1
Griswold, T; Johnson, DC	1
Feil, PD; Leszczynski, D; Manni, A; Santen, RJ; Santner, SJ; Tilson-Mallet, N; Wright, C	1
Daly, MJ; Dyas, J; Nicholls, PJ; Pourgholami, MH; Smith, HJ	1
Ahmann, FR; Crawford, ED; Kreis, W; Levasseur, Y	1
Brodie, AM; Coombes, RC; Dowsett, M; Goss, P; Wing, LY	1
Coombes, RC; Easton, D; Goss, PE; Singh, D; Wilkinson, JR; Williams, JC	1
Donahoe, PK; Hutson, JM; MacLaughlin, DT	1
Brodie, AM; Garrett, WM; Wing, LY	1
Dowsett, M; Jeffcoate, SL; Santen, RJ; Santner, SJ; Smith, IE	1
Siiteri, PK; Thompson, EA	1
Gower, DB	1
Carballeira, A; Durnhofer, F; Fishman, LM	1
Jeffries, CD; Wilkins, J	1
Gower, DB; Lessof, MH; Lyne, C	1
Abul-Hajj, YJ	2
Dowsett, M; Harris, AL; Jeffcoate, SL; McKinna, JA; Morgan, M; Smith, IE	1
Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE	2
Dowsett, M; Harris, AL; Jeffcoate, S; Smith, IE	1
Chilvers, CE; Dowsett, M; Easton, D; Jeffcoate, SL; Miller, J; Pocock, RD; Ponder, BA; Shearer, RJ	1
Smith, IE; Stuart-Harris, RC	1
Powles, TJ	1
Feil, PD; Santen, RJ; Santner, SJ; Tilson-Mallett, N	1
Osawa, Y; Rosen, H; Santen, RJ; Santner, SJ	1
Badder, EM; Lerman, S; Santen, R	1
Brodie, AM	2
Covey, DF; Etre, LA; MacIndoe, JH; Woods, GR	1
Rabe, D; Rabe, T; Runnebaum, B	1
Falvo, RE; Irwin, G; Samojlik, E; Santen, RJ; Worgul, TJ	1
Check, WA	1
Murray, R; Pitt, P	1
Auzéby, A; Bogdan, A; Touitou, Y	1
Aboul-Enein, HY; Ogbunude, PO	1
Casebolt, TL; Eto, I; Grubbs, CJ; Kelloff, GJ; Lubet, RA; Steele, VE	1
Cam, LL; Chen, S; Korzekwa, KR; Laughton, CA; Zhou, D	1
Bhatnagar, AS; King, EJ; Purba, HS; Richert, P	1
Dowsett, M; Jacobs, S; Lønning, PE; MacNeill, FA; Powles, TJ	1
Kanno, H; Kim, T; Kitawaki, J; Noguchi, T; Okada, H; Yamamoto, T	1
Höffken, K	1
Ekse, D; Lønning, PE	1
Düerkop, J; Hartmann, RW; Njar, VC	1
Boyle, T; Dukes, M; Edwards, PN; Large, M; Smith, IK	1
Frost, VJ; Helle, SI; Holly, JM; Lønning, PE; van der Stappen, JW	1
Anker, G; Geisler, J; Johannessen, DC; Lønning, PE	1
Durgam, VR; Tekmal, RR	1
Buzdar, AU; Roseman, BJ; Singletary, SE	1
Rubens, RD	1
Anderson, ED; Anderson, TJ; Cameron, DA; Chetty, U; Forrest, AP; Hawkins, RA; Leonard, RC; Levack, P	1
Campbell, DR; Kurzer, MS	1
Anker, GB; Johannessen, DC; Lien, EA; Lonning, PE; Refsum, H; Ueland, PM	1
Ahmadi, M; Delgado, PO; Nicholls, PJ; Perez, SF; Simons, C; Smith, HJ; Vinh, TK; Walters, HM	1
Blijham, GH; de Jong, PC	1
Bonneterre, J; Feutrie, ML	1
Harvey, HA; Santen, RJ	1
Ohmori, K; Ohta, A; Sugawara, S; Yamada, K	1
Bonneterre, J; Mauriac, L	1
Auvray, P; Bichat, F; Genne, P	1
de Crémoux, P	1
Blanco, JG; Bocco, JL; Flury, A; Genti-Raimondi, S; Gil, RR; Meragelman, TL	1
Cernich, J; Jacobson, JD; Moore, WV; Popovic, J	1
King, HR; Lee, PS; Pankhurst, NW	1
Ioannidis, JP; Mauri, D; Pavlidis, N; Polyzos, NP	1
Fox, J; Hamad, A; Kluk, M; Park, M; Turner, JE	1
Dutta, U; Pant, K	1
Menon, KM; Palaniappan, M	1
Bond, CS; Dick, IM; Ingley, E; Payne, EJ; Prince, RL; Wilson, SG	1

Reviews

24 review(s) available for aminoglutethimide and androstenedione

Article	Year
Mechanism and inhibition of cytochrome P-450 aromatase. Journal of medicinal chemistry, 1990, Volume: 33, Issue:11 Topics: Affinity Labels; Aromatase; Aromatase Inhibitors; Binding, Competitive; Humans; Molecular Structure; Photochemistry	1990
Developing steroidal aromatase inhibitors-an effective armament to win the battle against breast cancer. European journal of medicinal chemistry, 2015, Nov-13, Volume: 105 Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Female; Humans; Models, Molecular; Molecular Structure	2015
Kinetic, hormonal and clinical studies with aminoglutethimide in breast cancer. Cancer, 1977, Volume: 39, Issue:6 Suppl Topics: Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dexamethasone; Drug Therapy, Combination; Estradiol; Estrone; Female; Humans; Hydrocortisone; Menopause; Neoplasm Metastasis; Neoplasm Recurrence, Local; Thyrotropin; Thyroxine	1977
Aromatase inhibitors: clinical pharmacology and therapeutic implications in breast cancer. The Journal of international medical research, 1992, Volume: 20, Issue:4 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Letrozole; Nitriles; Triazoles	1992
Postmenopausal estrogen synthesis and metabolism: alterations caused by aromatase inhibitors used for the treatment of breast cancer. Journal of steroid biochemistry, 1990, Volume: 35, Issue:3-4 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Fadrozole; Female; Humans; Imidazoles; Menopause; Nitriles	1990
Recent progress in development of aromatase inhibitors. The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Humans; Imidazoles; Nitriles	1990
Clinical development of aromatase inhibitors for the treatment of breast and prostate cancer. The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Estrogen Antagonists; Fadrozole; Humans; Imidazoles; Nitriles	1990
Aromatase inhibitors in the treatment of advanced breast cancer. Cancer treatment reviews, 1989, Volume: 16, Issue:2 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Neoplasms, Hormone-Dependent; Nitriles	1989
Clinical use of aromatase inhibitors in the treatment of breast cancer. Cancer treatment and research, 1988, Volume: 39 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Estrogens; Female; Humans	1988
Aromatase in breast cancer and the role of aminoglutethimide and other aromatase inhibitors. Critical reviews in oncology/hematology, 1986, Volume: 5, Issue:4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Aminoglutethimide; Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Middle Aged; Rats; Tamoxifen	1986
Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways. Annals of the New York Academy of Sciences, 1986, Volume: 464 Topics: 17-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aminoglutethimide; Androstenedione; Animals; Aromatase; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Sulfatases; Testolactone	1986
Modifiers of steroid-hormone metabolism: a review of their chemistry, biochemistry and clinical applications. Journal of steroid biochemistry, 1974, Volume: 5, Issue:5 Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aminoglutethimide; Androgens; Androstenedione; Animals; Cholesterol; Dexamethasone; Estrogens; Estrone; Glutethimide; Hormones; Humans; Hydrocortisone; Methane; Metyrapone; Microscopy, Electron; Pharmacology; Phenols; Pregnenolone; Pyridines; Steroid Hydroxylases; Steroids; Time Factors	1974
Aminoglutethimide in the treatment of advanced breast cancer. Cancer treatment reviews, 1984, Volume: 11, Issue:3 Topics: Adrenalectomy; Aged; Aminoglutethimide; Androstenedione; Breast Neoplasms; Clinical Trials as Topic; Dehydroepiandrosterone; Drug Therapy, Combination; Estradiol; Estrone; Female; Glucocorticoids; Humans; Hydrocortisone; Hypophysectomy; Menopause; Middle Aged; Neoplasm Metastasis; Tamoxifen	1984
Aromatase, its inhibitors and their use in breast cancer treatment. Pharmacology & therapeutics, 1993, Volume: 60, Issue:3 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Half-Life; Humans; Neoplasms, Hormone-Dependent; Pargyline	1993
Experience with aromatase inhibitors in the treatment of advanced breast cancer. Cancer treatment reviews, 1993, Volume: 19 Suppl B Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Forecasting; Humans	1993
Use of aromatase inhibitors in postmenopausal women with advanced breast cancer. Journal of surgical oncology, 1997, Volume: 66, Issue:3 Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles	1997
New aromatase inhibitors for the treatment of advanced breast cancer in postmenopausal women. The Netherlands journal of medicine, 1999, Volume: 55, Issue:2 Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Triazoles	1999
[Aromatase inhibitors]. Bulletin du cancer, 1999, Volume: 86, Issue:10 Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles	1999
Use of aromatase inhibitors in breast carcinoma. Endocrine-related cancer, 1999, Volume: 6, Issue:1 Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Drug Interactions; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Tamoxifen; Triazoles	1999
[Preclinical evaluation of aromatase inhibitors antitumor activity]. Bulletin du cancer, 2000, Volume: 87 Spec No Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Models, Animal; Nitriles; Rats; Structure-Activity Relationship; Triazoles	2000
[Aromatase inhibitors: pharmacological aspects]. Bulletin du cancer, 2000, Volume: 87 Spec No Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles	2000
Use of aromatase inhibitors in children with short stature. Pediatric endocrinology reviews : PER, 2004, Volume: 2, Issue:1 Topics: Adult; Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Body Height; Child; Estrogens; Female; Growth Disorders; Humans; Letrozole; Male; Musculoskeletal System; Nitriles; Triazoles	2004
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis. Journal of the National Cancer Institute, 2006, Sep-20, Volume: 98, Issue:18 Topics: Adult; Aged; Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles	2006
Aromatase inhibitors: past, present and future in breast cancer therapy. Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:2 Topics: Aminoglutethimide; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles	2008

Trials

10 trial(s) available for aminoglutethimide and androstenedione

Article	Year
Influence of aminoglutethimide on plasma oestrogen levels in breast cancer patients on 4-hydroxyandrostenedione treatment. Breast cancer research and treatment, 1992, Volume: 23, Issue:1-2 Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Middle Aged; Pilot Projects	1992
Primary systemic therapy for operable breast cancer. British journal of cancer, 1991, Volume: 63, Issue:4 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Buserelin; Combined Modality Therapy; Female; Goserelin; Humans; Lymphatic Metastasis; Middle Aged; Ovariectomy; Tamoxifen	1991
Low dose aminoglutethimide without hydrocortisone for the treatment of advanced postmenopausal breast cancer. European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Aminoglutethimide; Androstenedione; Breast Neoplasms; Drug Evaluation; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Menopause; Middle Aged; Receptors, Estrogen	1989
Aromatase in breast cancer and the role of aminoglutethimide and other aromatase inhibitors. Critical reviews in oncology/hematology, 1986, Volume: 5, Issue:4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Aminoglutethimide; Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Middle Aged; Rats; Tamoxifen	1986
Hydrocortisone alone vs hydrocortisone plus aminoglutethimide: a comparison of the endocrine effects in postmenopausal breast cancer. European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:4 Topics: Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Estradiol; Estrone; Female; Humans; Hydrocortisone; Menopause; Middle Aged; Time Factors	1984
Aminoglutethimide in the treatment of advanced breast cancer. Cancer treatment reviews, 1984, Volume: 11, Issue:3 Topics: Adrenalectomy; Aged; Aminoglutethimide; Androstenedione; Breast Neoplasms; Clinical Trials as Topic; Dehydroepiandrosterone; Drug Therapy, Combination; Estradiol; Estrone; Female; Glucocorticoids; Humans; Hydrocortisone; Hypophysectomy; Menopause; Middle Aged; Neoplasm Metastasis; Tamoxifen	1984
The role of aromatase inhibitors in breast cancer. Seminars in oncology, 1983, Volume: 10, Issue:4 Suppl 4 Topics: Aged; Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrone; Female; Humans; Menopause; Middle Aged; Oxidoreductases; Prognosis	1983
Aromatase inhibition with 4-OHAndrostenedione after prior aromatase inhibition with aminoglutethimide in women with advanced breast cancer. Breast cancer research and treatment, 1995, Volume: 35, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Humans; Middle Aged; Neoplasm Staging; Ovariectomy; Postmenopause	1995
Treatment with formestane alone and in combination with aminoglutethimide in heavily pretreated breast cancer patients: clinical and endocrine effects. European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Middle Aged	1996
Primary systemic therapy for operable breast cancer--10-year survival data after chemotherapy and hormone therapy. British journal of cancer, 1997, Volume: 76, Issue:8 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Goserelin; Humans; Hydrocortisone; Lymphatic Metastasis; Middle Aged; Neoplasms, Hormone-Dependent; Ovariectomy; Prednisone; Preoperative Care; Tamoxifen; Treatment Outcome; Vincristine	1997

Other Studies

89 other study(ies) available for aminoglutethimide and androstenedione

Article	Year
Pyridyl-substituted tetrahydrocyclopropa[a]naphthalenes: highly active and selective inhibitors of P450 arom. Journal of medicinal chemistry, 1995, Jun-09, Volume: 38, Issue:12 Topics: Adrenal Glands; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cattle; Female; Humans; Liver; Male; Mammary Neoplasms, Experimental; Naphthalenes; Ovary; Placenta; Pyridines; Rats; Testis	1995
Aromatase inhibitors. Syntheses and structure-activity studies of novel pyridyl-substituted indanones, indans, and tetralins. Journal of medicinal chemistry, 1994, Apr-29, Volume: 37, Issue:9 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Cattle; Female; Humans; Indans; Mammary Neoplasms, Experimental; Microsomes; Molecular Structure; Organ Size; Placenta; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Testosterone; Tetrahydronaphthalenes; Uterus	1994
Mechanism of action of aminoglutethimide in breast cancer. Lancet (London, England), 1979, Jan-06, Volume: 1, Issue:8106 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Breast Neoplasms; Estradiol; Estrogen Antagonists; Estrone; Female; Humans; Menopause; Middle Aged; Neoplasm Metastasis; Testosterone	1979
Further studies on the relationship of adrenal and gonadal steroids in pubertal development in female rats. Hormone research, 1979, Volume: 10, Issue:2-3 Topics: Adrenal Glands; Adrenalectomy; Age Factors; Aminoglutethimide; Androstenedione; Animals; Corticosterone; Dehydroepiandrosterone; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Rats; Sexual Maturation	1979
Adrenal suppression with aminoglutethimide. III. Comparison of plasma delta 4- and delta 5-steroids in postmenopausal women treated for breast carcinoma. The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:4 Topics: 17-alpha-Hydroxypregnenolone; Aminoglutethimide; Androgens; Androstenedione; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydroxyprogesterones; Menopause; Progesterone; Progestins	1978
Aminoglutethimide inhibits extraglandular estrogen production in postmenopausal women with breast carcinoma. The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:6 Topics: Adult; Aminoglutethimide; Androstenedione; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Menopause; Metabolic Clearance Rate; Middle Aged	1978
Inhibition of testosterone-induced sexual behavior in the castrated male rat by aromatase blockers. Hormones and behavior, 1977, Volume: 9, Issue:3 Topics: Aminoglutethimide; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Castration; Copulation; Dihydrotestosterone; Estradiol; Male; Oxidoreductases; Rats; Sexual Behavior, Animal; Testosterone	1977
Medical adrenalectomy and plasma steroids in advanced breast carcinoma. Surgery, 1978, Volume: 83, Issue:1 Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Aminoglutethimide; Androstenedione; Breast Neoplasms; Depression, Chemical; Dexamethasone; Estradiol; Estrone; Female; Humans; Hydrocortisone	1978
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism. Archives of internal medicine, 1978, Volume: 138, Issue:2 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Androstenedione; Cushing Syndrome; Dexamethasone; Estrogens; Feminization; Humans; Hyperparathyroidism; Male; Metyrapone; Mitotane; Paraneoplastic Endocrine Syndromes; Parathyroid Hormone; Testosterone	1978
Medical adrenalectomy with aminoglutethimide: clinical studies in postmenopausal patients with metastatic breast carcinoma. Annals of surgery, 1978, Volume: 187, Issue:5 Topics: Adrenal Cortex; Adrenalectomy; Aldosterone; Aminoglutethimide; Androstenedione; Bone Neoplasms; Breast Neoplasms; Drug Evaluation; Estrogens; Female; Follow-Up Studies; Humans; Hypophysectomy; Lung Neoplasms; Menopause; Middle Aged; Neoplasm Metastasis; Prolactin; Radiography; Remission, Spontaneous; Thyrotropin; Thyroxine; Time Factors	1978
Adrenal suppression with aminoglutethimide. II. Differential effects of aminoglutethimide on plasma androstenedione and estrogen levels. The Journal of clinical endocrinology and metabolism, 1977, Volume: 45, Issue:3 Topics: Adrenal Glands; Aminoglutethimide; Androstenedione; Breast Neoplasms; Castration; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Male; Menopause	1977
Oocytic meiosis in cultured rat follicles during inhibition of steroidogenesis. Acta endocrinologica, 1976, Volume: 83, Issue:1 Topics: Aminoglutethimide; Androstenedione; Animals; Culture Media; Culture Techniques; Cyanoketone; Depression, Chemical; Estradiol; Female; Luteinizing Hormone; Meiosis; Oocytes; Ovarian Follicle; Ovum; Progesterone; Prostaglandins E; Radioimmunoassay; Rats; Secretory Rate	1976
Effect of some antiestrogens and aromatase inhibitors on androgen induced sexual behavior in castrated male rats. Hormones and behavior, 1976, Volume: 7, Issue:3 Topics: Aminoglutethimide; Androstenedione; Animals; Castration; Clomiphene; Drug Interactions; Ejaculation; Ethamoxytriphetol; Male; Metyrapone; Rats; Sexual Behavior, Animal; Tamoxifen; Testosterone; Time Factors	1976
Effects of gonadotrophins on the cumulus oophorus of isolated rat Graafian follicles. Acta physiologica Scandinavica, 1976, Volume: 96, Issue:4 Topics: Aminoglutethimide; Androstenedione; Animals; Cyanoketone; Drug Interactions; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Hyaluronoglucosaminidase; Luteinizing Hormone; Oocytes; Ovarian Follicle; Ovum; Progesterone; Prolactin; Rats	1976
Some 1-, and 3-substituted 3-(4'-aminophenyl)pyrrolidine-2,5-diones as selective inhibitors of aromatase. Journal of enzyme inhibition, 1992, Volume: 6, Issue:4 Topics: Adrenal Glands; Aminoglutethimide; Androstenedione; Aniline Compounds; Animals; Aromatase Inhibitors; Cattle; Humans; Microsomes, Liver; Placenta; Rats; Structure-Activity Relationship; Succinimides; Testosterone	1992
Disruption of ovarian development in alligator embryos treated with an aromatase inhibitor. General and comparative endocrinology, 1992, Volume: 86, Issue:1 Topics: Alligators and Crocodiles; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Cyproterone; Cyproterone Acetate; Estradiol; Fadrozole; Female; Imidazoles; Male; Nitriles; Ovary; Tamoxifen; Testis	1992
[Aminoglutethimide and aminoglutethimide+tamoxifen treatment for advanced breast cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:12 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Estrone; Female; Humans; Middle Aged; Survival Rate; Tamoxifen	1992
Low-dose aminoglutethimide in postmenopausal breast cancer: effects on adrenal and thyroid hormone secretion. European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:7 Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Aminoglutethimide; Androstenedione; Breast Neoplasms; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Menopause; Middle Aged; Thyroxine; Triiodothyronine	1991
Measurement of aromatisation by a urine technique suitable for the evaluation of aromatase inhibitors in vivo. Journal of enzyme inhibition, 1991, Volume: 4, Issue:4 Topics: Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Estrone; Female; Humans	1991
[The use of aminoglutethimide in the treatment of metastatic breast cancer]. Minerva ginecologica, 1991, Volume: 43, Issue:12 Topics: Adrenal Glands; Age Factors; Aminoglutethimide; Androstenedione; Breast Neoplasms; Female; Humans; Menopause; Neoplasm Metastasis	1991
Structure-function studies of human aromatase by site-directed mutagenesis: kinetic properties of mutants Pro-308----Phe, Tyr-361----Phe, Tyr-361----Leu, and Phe-406----Arg. Proceedings of the National Academy of Sciences of the United States of America, 1991, Jan-15, Volume: 88, Issue:2 Topics: Amino Acid Sequence; Aminoglutethimide; Androstenedione; Animals; Arginine; Aromatase; Base Sequence; Cell Line; Humans; Kinetics; Leucine; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Oligonucleotide Probes; Phenylalanine; Proline; Substrate Specificity; Testosterone; Transfection; Tyrosine	1991
Endocrine and clinical aspects of new compounds for treatment of hormone-related cancer in gynecology. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1990, Volume: 118 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Buserelin; Female; Goserelin; Humans; Neoplasms, Hormone-Dependent; Tamoxifen	1990
Stable expression of human aromatase complementary DNA in mammalian cells: a useful system for aromatase inhibitor screening. Cancer research, 1990, Nov-01, Volume: 50, Issue:21 Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Base Sequence; Blotting, Southern; Cricetinae; Cricetulus; DNA; Female; Gene Expression; Humans; Kinetics; Molecular Sequence Data; Ovary; Placenta; Plasmids; Polymerase Chain Reaction; Pregnancy; Transfection; Tumor Cells, Cultured	1990
Novel irreversible aromatase inhibitors. Annals of the New York Academy of Sciences, 1990, Volume: 595 Topics: Aminoglutethimide; Androstadienes; Androstenedione; Animals; Aromatase Inhibitors; Female; Gonadotropins, Equine; Humans; In Vitro Techniques; Kinetics; Microsomes; Ovary; Pargyline; Placenta; Rats; Rats, Inbred Strains	1990
Crystallographic and molecular modeling studies on 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione and its butyl analogue, inhibitors of mammalian aromatase. Comparison with natural substrates: prediction of enantioselectivity for N-alkyl derivatives. Journal of medicinal chemistry, 1990, Volume: 33, Issue:9 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Chemical Phenomena; Chemistry; Crystallography; Humans; Models, Molecular; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship	1990
Androstenedione and androst-5-ene-3 beta,17 beta-diol stimulate DMBA-induced rat mammary tumors--role of aromatase. Breast cancer research and treatment, 1989, Volume: 13, Issue:1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Androstenediol; Androstenediols; Androstenedione; Animals; Aromatase; Female; Flutamide; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Inbred Strains; Silicone Elastomers	1989
An in vitro method to determine the selective inhibition of estrogen biosynthesis by aromatase inhibitors. Journal of steroid biochemistry, 1989, Volume: 33, Issue:1 Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Cricetinae; Estrogen Antagonists; Estrogens; Estrus; Fadrozole; Female; Imidazoles; Kinetics; Luteinizing Hormone; Mesocricetus; Nitriles; Ovary; Progesterone; Testolactone; Testosterone	1989
Response to endocrine manipulation and oestrogen receptor concentration in large operable primary breast cancer. British journal of cancer, 1989, Volume: 60, Issue:2 Topics: Aminoglutethimide; Androstenedione; Breast Neoplasms; Buserelin; Female; Goserelin; Humans; Menopause; Receptors, Estrogen; Tamoxifen	1989
Formation of 4-oestrene-3,17-dione (19-norandrostenedione) by porcine granulosa cells in vitro is inhibited by the aromatase inhibitor 4-hydroxyandrostenedione and the cytochrome P-450 inhibitors aminoglutethimide phosphate and ketoconazole. The Journal of endocrinology, 1989, Volume: 120, Issue:2 Topics: Aminoglutethimide; Androstenedione; Animals; Cells, Cultured; Female; Granulosa Cells; Ketoconazole; Swine	1989
A comparison of the endocrine effects of low dose aminoglutethimide with and without hydrocortisone in postmenopausal breast cancer patients. British journal of cancer, 1985, Volume: 52, Issue:4 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression, Chemical; Drug Combinations; Estradiol; Estrone; Female; Humans; Hydrocortisone; Menopause; Middle Aged; Time Factors	1985
Endocrine effects of low dose aminoglutethimide with hydrocortisone--an optimal hormone suppressive regimen. Breast cancer research and treatment, 1986, Volume: 7 Suppl Topics: Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Menopause	1986
Endocrine effects of aminoglutethimide plus hydrocortisone versus effects of high dose of hydrocortisone alone in postmenopausal metastatic breast cancer. European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:9 Topics: Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Hormones; Humans; Hydrocortisone; Middle Aged; Sex Hormone-Binding Globulin; Thyrotropin; Thyroxine	1987
Endocrine effects of low dose aminoglutethimide as an aromatase inhibitor in the treatment of breast cancer. Clinical endocrinology, 1985, Volume: 22, Issue:2 Topics: Adrenocorticotropic Hormone; Aged; Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Depression, Chemical; Drug Therapy, Combination; Estradiol; Estrone; Female; Humans; Hydrocortisone; Menopause; Middle Aged; Oxidoreductases; Testosterone	1985
Adenosine 3',5'-monophosphate-mediated induction of 17 alpha-hydroxylase and C 17-20 lyase activities in cultured mouse Leydig cells is enhanced by inhibition of steroid biosynthesis. Endocrinology, 1986, Volume: 118, Issue:3 Topics: Aldehyde-Lyases; Aminoglutethimide; Androstenedione; Animals; Cyclic AMP; Cytochrome P-450 Enzyme System; Enzyme Induction; Estradiol; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; Mice; Microsomes; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Testosterone	1986
The effects of aminoglutethimide and hydrocortisone, alone and combined, on androgen levels in post-orchiectomy prostatic cancer patients. British journal of cancer, 1988, Volume: 57, Issue:2 Topics: Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Humans; Hydrocortisone; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Testosterone; Time Factors	1988
Structure-activity relationships of the inhibition of human placental aromatase by imidazole drugs including ketoconazole. Journal of steroid biochemistry, 1988, Volume: 31, Issue:1 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Humans; Imidazoles; Ketoconazole; Microsomes; Placenta; Structure-Activity Relationship	1988
[The inhibitory effect of miconazole on aromatase activity for androstenedione in human placental and ovarian preparations]. Nihon Naibunpi Gakkai zasshi, 1987, Nov-20, Volume: 63, Issue:11 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Female; Humans; In Vitro Techniques; Miconazole; Ovary; Placenta; Pregnancy; Testolactone	1987
Mammary steroidogenesis: therapeutic implications. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1987, Volume: 14, Issue:4 Topics: 17-Hydroxysteroid Dehydrogenases; Adipose Tissue; Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; In Vitro Techniques	1987
Relationship between in vivo and in vitro 17 alpha-hydroxylase and C17,20-lyase activity in ovaries of immature hypophysectomized rats treated chronically with human chorionic gonadotropin. Journal of steroid biochemistry, 1986, Volume: 24, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Aminoglutethimide; Androstenedione; Animals; Chorionic Gonadotropin; Cycloheximide; Dactinomycin; Female; Hydroxyprogesterones; Hypophysectomy; In Vitro Techniques; Microsomes; Mitochondria; Ovary; Rats; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases	1986
Inhibition of aromatase activity in the rat by aminoglutethimide and related compounds. Journal of steroid biochemistry, 1987, Volume: 26, Issue:3 Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Estradiol; Female; Ovary; Rats; Rats, Inbred Strains; Testosterone	1987
Adrenal steroid levels in castrated men with prostatic carcinoma treated with aminoglutethimide plus hydrocortisone. Cancer research, 1987, Sep-01, Volume: 47, Issue:17 Topics: Aminoglutethimide; Androgens; Androstenedione; Drug Therapy, Combination; Humans; Hydrocortisone; Male; Orchiectomy; Prostatic Neoplasms; Testosterone	1987
Aromatase inhibitors and the treatment of breast cancer. Journal of steroid biochemistry, 1986, Volume: 24, Issue:1 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Female; Humans; Kinetics; Luteinizing Hormone; Macaca mulatta; Mammary Neoplasms, Experimental; Menopause; Middle Aged; Neoplasms, Hormone-Dependent; Ovary; Rats; Tamoxifen	1986
Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response. Cancer research, 1986, Volume: 46, Issue:9 Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Dihydrotestosterone; Female; Humans; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Ovariectomy; Rats; Tamoxifen	1986
Steroid modulation of Mullerian duct regression in the chick embryo. General and comparative endocrinology, 1985, Volume: 57, Issue:1 Topics: Aminoglutethimide; Androstenedione; Animals; Anti-Mullerian Hormone; Chick Embryo; Drug Interactions; Estrogen Antagonists; Estrogens; Female; Glycoproteins; Growth Inhibitors; Male; Mullerian Ducts; Norethindrone; Pyrrolidines; Tamoxifen; Testicular Hormones; Thiophenes	1985
Effects of aromatase inhibitors, aminoglutethimide, and 4-hydroxyandrostenedione on cyclic rats and rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors. Cancer research, 1985, Volume: 45, Issue:6 Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Estradiol; Estrus; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Oxidoreductases; Pregnancy; Rats; Rats, Inbred Strains	1985
Effective inhibition by low dose aminoglutethimide of peripheral aromatization in postmenopausal breast cancer patients. British journal of cancer, 1985, Volume: 52, Issue:1 Topics: Aged; Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estrone; Female; Humans; Middle Aged; Oxidoreductases	1985
The involvement of human placental microsomal cytochrome P-450 in aromatization. The Journal of biological chemistry, 1974, Sep-10, Volume: 249, Issue:17 Topics: Aminoglutethimide; Androstenedione; Animals; Binding Sites; Binding, Competitive; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Female; Humans; Kinetics; Metyrapone; Microsomes; Microsomes, Liver; Nandrolone; Placenta; Pregnancy; Proadifen; Protein Binding; Rabbits; Receptors, Cell Surface; Spectrophotometry; Spectrophotometry, Ultraviolet; Steroids; Swine; Tritium	1974
Effects of aminoglutethimide, metyrapone, and ascorbic acid on testicular metabolism of cholesterol. Metabolism: clinical and experimental, 1974, Volume: 23, Issue:12 Topics: Aminoglutethimide; Androstanes; Androstenedione; Animals; Ascorbic Acid; Carbon Radioisotopes; Cell-Free System; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Female; Hydroxyprogesterones; Hydroxysteroids; Male; Metyrapone; Mitochondria; Pregnenolone; Progesterone; Rats; Testis; Testosterone; Tritium	1974
Effect of exogenous steroids and inhibitors of steroidogenesis on endotoxin shock. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 142, Issue:2 Topics: Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Androstenedione; Animals; Butanones; Corticosterone; Desoxycorticosterone; Endotoxins; Hydrocortisone; Hydroxyprogesterones; Lethal Dose 50; Male; Metyrapone; Mice; Mice, Inbred ICR; Pregnenes; Pregnenolone; Progesterone; Shock, Septic	1973
Proceedings: Effects of aminoglutethimide and SU 10'603 on the biosynthesis of C19 steroids. The Journal of endocrinology, 1974, Volume: 61, Issue:1 Topics: Aminoglutethimide; Androstenedione; Animals; Carbon Radioisotopes; Cholesterol; In Vitro Techniques; Male; Mixed Function Oxygenases; Naphthalenes; Pregnenolone; Progesterone; Pyridines; Rats; Steroids; Swine; Testis; Testosterone	1974
Comparative studies of aromatase inhibitors in relation to the significance of estrogen synthesis in human mammary tumors. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aminoglutethimide; Androgens; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cyanoketone; Dehydroepiandrosterone; Estrogens; Female; Humans; Kinetics; Oxidoreductases; Receptors, Estrogen	1982
Endocrine and therapeutic effects of aminoglutethimide in premenopausal patients with breast cancer. The Journal of clinical endocrinology and metabolism, 1982, Volume: 55, Issue:4 Topics: Adult; Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Estradiol; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Menopause; Menstruation; Middle Aged	1982
Endocrine effects of low dose aminoglutethimide alone in advanced postmenopausal breast cancer. British journal of cancer, 1983, Volume: 47, Issue:5 Topics: 17-alpha-Hydroxyprogesterone; Adult; Aged; Aminoglutethimide; Androstenedione; Breast Neoplasms; Cosyntropin; Dehydroepiandrosterone; Drug Administration Schedule; Drug Therapy, Combination; Estrone; Female; Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Menopause; Middle Aged	1983
Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy. The Journal of clinical endocrinology and metabolism, 1984, Volume: 58, Issue:1 Topics: Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hormones; Humans; Hydrocortisone; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Prolactin	1984
Response to aminoglutethimide and cortisone acetate in advanced prostatic cancer. British journal of cancer, 1984, Volume: 50, Issue:6 Topics: Adenocarcinoma; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Cortisone; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Male; Middle Aged; Prostatic Neoplasms; Sleep Stages; Testosterone	1984
Potency of the effect of D-stereoisomer of aminoglutethimide on adrenal and extraadrenal steroidogenesis. The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:3 Topics: Adrenal Glands; Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Stereoisomerism	1980
Biological significance of aromatase activity in human breast tumors. The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:6 Topics: Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrone; Female; Humans; Oxidoreductases; Receptors, Estrogen; Receptors, Progesterone; Testolactone	1983
Additive effects of aminoglutethimide, testololactone, and 4-hydroxyandrostenedione as inhibitors of aromatase. Journal of steroid biochemistry, 1984, Volume: 20, Issue:6A Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy; Substrate Specificity; Testolactone; Testosterone Congeners	1984
Aminoglutethimide stimulates extra adrenal delta-4-androstenedione production. The Journal of surgical research, 1983, Volume: 34, Issue:4 Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Aminoglutethimide; Androstenedione; Animals; Castration; Dogs; Female; Hydrocortisone; Hydroxyprogesterones	1983
Overview of recent development of aromatase inhibitors. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aminoglutethimide; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; In Vitro Techniques; Macaca mulatta; Male; Oxidoreductases; Pregnancy; Rats	1982
Comparative studies of aromatase inhibitors in cultured human breast cancer cells. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Female; Humans; Oxidoreductases; Pargyline; Receptors, Estrogen; Receptors, Progesterone; Testolactone; Testosterone	1982
New aromatase assay and its application for inhibitory studies of aminoglutethimide on microsomes of human term placenta. Journal of steroid biochemistry, 1982, Volume: 17, Issue:3 Topics: Aminoglutethimide; Androstenedione; Aromatase; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy	1982
Evidence that brain aromatization regulates LH secretion in the male dog. The American journal of physiology, 1981, Volume: 241, Issue:3 Topics: Aminoglutethimide; Androgens; Androstenedione; Animals; Aromatase; Brain; Dihydrotestosterone; Dogs; Estradiol; Estrogens; Estrone; Feedback; Hydrocortisone; Kinetics; Luteinizing Hormone; Male; Oxidoreductases; Testosterone	1981
Medical adrenalectomy may replace surgery for advanced breast cancer. JAMA, 1980, Jul-04, Volume: 244, Issue:1 Topics: Adipose Tissue; Adrenal Glands; Adrenalectomy; Aminoglutethimide; Androstenedione; Breast Neoplasms; Cholesterol; Estradiol; Estrogen Antagonists; Female; Humans; Pregnenolone	1980
Inhibition of androgen aromatization in human breast cancer. Journal of steroid biochemistry, 1980, Volume: 13, Issue:12 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Estradiol; Estrone; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy	1980
An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione. The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:5 Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Aged; Aldehyde-Lyases; Aminoglutethimide; Androstenedione; Carcinoma; Child; Cytochrome P-450 Enzyme System; Female; Humans; Hyperaldosteronism; Male; Metyrapone; Middle Aged; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase	1995
In vitro inhibition of aromatase by the enantiomers of aminoglutethimide and analogs. Chirality, 1994, Volume: 6, Issue:8 Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Female; Glutethimide; In Vitro Techniques; Microsomes; Ovary; Rats; Stereoisomerism	1994
Chemopreventive effects of the aromatase inhibitors vorozole (R-83842) and 4-hydroxyandrostenedione in the methylnitrosourea (MNU)-induced mammary tumor model in Sprague-Dawley rats. Carcinogenesis, 1994, Volume: 15, Issue:12 Topics: Adenocarcinoma; Aminoglutethimide; Androstenedione; Animals; Anticarcinogenic Agents; Aromatase Inhibitors; Drug Screening Assays, Antitumor; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazoles	1994
Mutagenesis study at a postulated hydrophobic region near the active site of aromatase cytochrome P450. The Journal of biological chemistry, 1994, Jul-29, Volume: 269, Issue:30 Topics: Amino Acid Sequence; Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Computer Simulation; DNA Mutational Analysis; Dose-Response Relationship, Drug; Fadrozole; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship	1994
Effect of aromatase inhibitors on estrogen 2-hydroxylase in rat liver. The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:2-3 Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Fadrozole; Female; Ketoconazole; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Substrate Specificity	1994
Combined treatment with 4-hydroxyandrostenedione and aminoglutethimide: effects on aromatase inhibition and oestrogen suppression. British journal of cancer, 1994, Volume: 69, Issue:6 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Estrogens; Female; Humans; Middle Aged; Postmenopause; Radioisotope Dilution Technique	1994
Growth suppression of MCF-7 human breast cancer cells by aromatase inhibitors: a new system for aromatase inhibitor screening. The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6 Topics: Aminoglutethimide; Androstenedione; Androstenols; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Fadrozole; Female; Humans; Kinetics; Tumor Cells, Cultured	1993
A sensitive assay for measurement of plasma estrone sulphate in patients on treatment with aromatase inhibitors. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrone; Female; Humans; Hydrolysis; Menopause; Radioimmunoassay; Sensitivity and Specificity	1995
Novel 19-(cyclopropylamino)-androst-4-en-3,17-dione: a mechanism-based inhibitor of aromatase. Journal of enzyme inhibition, 1996, Volume: 10, Issue:1 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Cyclopropanes; Enzyme Inhibitors; Enzyme Stability; Estradiol; Humans; Kinetics; Magnetic Resonance Spectroscopy; Microsomes; Molecular Structure; NADP; Placenta; Steroids; Testosterone	1996
The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033)--a potent, selective aromatase inhibitor. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:4 Topics: Adrenal Glands; Aminoglutethimide; Anastrozole; Androstenedione; Animals; Aromatase Inhibitors; Cortodoxone; Enzyme Inhibitors; Fadrozole; Female; Hormones; Humans; Macaca nemestrina; Male; Metyrapone; Nitriles; Organ Size; Potassium; Prostate; Rats; Rats, Wistar; Seminal Vesicles; Sodium; Triazoles; Uterus	1996
Effects of treatment with megestrol acetate, aminoglutethimide, or formestane on insulin-like growth factor (IGF) I and II, IGF-binding proteins (IGFBPs), and IGFBP-3 protease status in patients with advanced breast cancer. The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:6 Topics: Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Endopeptidases; Female; Humans; Insulin-Like Growth Factor Binding Proteins; Megestrol Acetate; Middle Aged; Radioimmunoassay; Somatomedins	1996
Aromatase inhibitors come of age. Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:7 Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Nitriles; Triazoles	1997
A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene. Cancer letters, 1997, Sep-16, Volume: 118, Issue:1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Analysis of Variance; Anastrozole; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Fadrozole; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Ovariectomy; Postmenopause; Triazoles; Tumor Cells, Cultured	1997
Aromatase inhibitors for breast cancer--further progress. European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:7 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Megestrol Acetate	1997
Flavonoid inhibition of aromatase enzyme activity in human preadipocytes. The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:3 Topics: Adipocytes; Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Kinetics; Molecular Structure	1993
Influence of aromatase inhibitors on plasma total homocysteine in postmenopausal breast cancer patients. Clinical chemistry, 1999, Volume: 45, Issue:2 Topics: Aminoglutethimide; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Creatinine; Enzyme Inhibitors; Estrogen Antagonists; Homocysteine; Humans; Postmenopause; Vitamins	1999
1-[(Benzofuran-2-yl)phenylmethyl]-triazoles and -tetrazoles - potent competitive inhibitors of aromatase. Bioorganic & medicinal chemistry letters, 1999, Jul-19, Volume: 9, Issue:14 Topics: Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Benzofurans; Enzyme Inhibitors; Female; Humans; Inhibitory Concentration 50; Ketones; Placenta; Pregnancy; Structure-Activity Relationship; Tetrazoles; Triazoles	1999
Effect of 3,6-dimethylpyrazine-2-thiol on androstenedione-induced increase of uterine weight in female rats. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:12 Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Organ Size; Pregnancy; Pyrazines; Rats; Rats, Wistar; Testosterone; Uterus	1999
[Aromatase inhibitors]. Bulletin du cancer, 2000, Volume: 87 Spec No Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Tamoxifen	2000
Aromatase inhibition by an 11,13-dihydroderivative of a sesquiterpene lactone. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3 Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Cell Line; Cell Survival; Choriocarcinoma; Dose-Response Relationship, Drug; Female; Humans; Hypertrophy; Lactones; Mice; Microsomes; Mitochondria; Organ Size; Placenta; Sesquiterpenes; Spectrum Analysis; Structure-Activity Relationship; Uterine Diseases; Uterine Neoplasms	2001
Effects of aromatase inhibitors on in vitro steroidogenesis by Atlantic salmon (Salmo salar) gonadal and brain tissue. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2006, Volume: 145, Issue:2 Topics: Aminoglutethimide; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Brain; Estradiol; Fadrozole; Female; Miconazole; Ovarian Follicle; Salmo salar; Testosterone	2006
The effects of aromatase inhibitors and selective estrogen receptor modulators on eye development in the zebrafish (Danio rerio). Current eye research, 2007, Volume: 32, Issue:10 Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Clomiphene; Embryo, Nonmammalian; Embryonic Development; Estrogens; Eye; Retina; Selective Estrogen Receptor Modulators; Tamoxifen; Zebrafish	2007
Regulation of sterol regulatory element-binding transcription factor 1a by human chorionic gonadotropin and insulin in cultured rat theca-interstitial cells. Biology of reproduction, 2009, Volume: 81, Issue:2 Topics: Aminoglutethimide; AMP-Activated Protein Kinases; Analysis of Variance; Androgens; Androstenedione; Animals; Cells, Cultured; Cholesterol; Chorionic Gonadotropin; Female; Gene Expression Regulation; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Insulin; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Phosphoinositide-3 Kinase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Sprague-Dawley; Steroid 17-alpha-Hydroxylase; Sterol Regulatory Element Binding Protein 1; Theca Cells	2009
In vitro kinetic properties of the Thr201Met variant of human aromatase gene CYP19A1: functional responses to substrate and product inhibition and enzyme inhibitors. The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:8 Topics: Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Cell Line; Humans; Kinetics; Protein Structure, Secondary; Structure-Activity Relationship	2009