Compounds > amiloride
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amiloride and thiophenes

amiloride has been researched along with thiophenes in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's6 (54.55)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bridges, AJ; Lee, A; Littlefield, BA; Schwartz, CE; Towle, MJ1
Sasaki, T; Satoh, M; Shimura, S; Shirato, K; Takishima, T; Yamada, K1
Bridges, AJ; Lee, A; Littlefield, BA; Maduakor, EC; Schwartz, CE; Towle, MJ1
Alonso, DF; Bal de Kier Joffé, E; Davel, L; Farías, EF; Ladeda, V; Puricelli, L1
Evans, DM; Sloan-Stakleff, K1
Arroyo de Prada, N; Graeff, H; Luther, T; Magdolen, U; Magdolen, V; Muehlenweg, B; Reuning, U; Schmitt, M; Sperl, S; Wilhelm, OG1
Maekawa, M; Murayama, T; Nomura, Y1
Butler, C; Dorwin, S; Giranda, VL; Hulkower, KI; Klinghofer, V; McGonigal, T; Nienaber, V; Richardson, P; Rockway, T; Sarthy, A; Smith, R; Stewart, K; Weitzberg, M; Wendt, M; Zhao, X1
Avila, MY; Civan, MM; Seidler, RW; Stone, RA1
El Fahime, E; Lafreniere, JF; Mills, P; Tremblay, JP1
Ali, Q; Hussain, T1

Reviews

1 review(s) available for amiloride and thiophenes

ArticleYear
Natural and synthetic inhibitors of the tumor-associated serine protease urokinase-type plasminogen activator.
    Advances in experimental medicine and biology, 2000, Volume: 477

    Topics: Amidines; Amiloride; Animals; Benzamidines; Guanidines; Mice; Mice, Knockout; Models, Biological; Molecular Structure; Neoplasm Invasiveness; Neoplasm Proteins; Phenotype; Plasminogen Activator Inhibitor 1; Plasminogen Activator Inhibitor 2; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Serine Proteinase Inhibitors; Serpins; Structure-Activity Relationship; Thiophenes; Urokinase-Type Plasminogen Activator

2000

Other Studies

10 other study(ies) available for amiloride and thiophenes

ArticleYear
The synthesis of three 4-substituted benzo[b]thiophene-2-carboxamidines as potent and selective inhibitors of urokinase.
    Bioorganic & medicinal chemistry, 1993, Volume: 1, Issue:6

    Topics: Amidines; Amiloride; Drug Evaluation, Preclinical; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship; Thiophenes; Urokinase-Type Plasminogen Activator

1993
An expectorant, stepronin, reduces airway secretion in vitro.
    Respiration; international review of thoracic diseases, 1994, Volume: 61, Issue:1

    Topics: Amiloride; Animals; Cats; Culture Techniques; Dogs; Dose-Response Relationship, Drug; Epithelium; Expectorants; Female; Glycine; Indomethacin; Isoproterenol; Male; Membrane Potentials; Mucus; Structure-Activity Relationship; Sulfides; Thiophenes; Trachea

1994
Inhibition of urokinase by 4-substituted benzo[b]thiophene-2-carboxamidines: an important new class of selective synthetic urokinase inhibitor.
    Cancer research, 1993, Jun-01, Volume: 53, Issue:11

    Topics: Amidines; Amiloride; Cell Movement; Chymotrypsin; Fibrinolysin; Humans; Kallikreins; Pancreatic Elastase; Thiophenes; Thrombin; Tissue Plasminogen Activator; Trypsin Inhibitors; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1993
Effects of synthetic urokinase inhibitors on local invasion and metastasis in a murine mammary tumor model.
    Breast cancer research and treatment, 1996, Volume: 40, Issue:3

    Topics: Amidines; Amiloride; Animals; Antineoplastic Agents; Cell Division; Diuretics; Enzyme Inhibitors; Female; Fibrinolysis; Fibronectins; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Thiophenes; Triamterene; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1996
Suppression of the invasive capacity of human breast cancer cells by inhibition of urokinase plasminogen activator via amiloride and B428.
    The American surgeon, 2000, Volume: 66, Issue:5

    Topics: Amidines; Amiloride; Breast Neoplasms; Cell Division; Humans; Neoplasm Invasiveness; Serine Proteinase Inhibitors; Thiophenes; Tumor Cells, Cultured

2000
Involvement of noradrenaline transporters in S-nitrosocysteine-stimulated noradrenaline release from rat brain slices: existence of functional Na(+)-independent transporter activity.
    Neurochemistry international, 2001, Volume: 38, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Amiloride; Animals; Biological Transport; Brain; Carrier Proteins; Central Nervous System Stimulants; Cerebral Cortex; Cysteine; Desipramine; Diethylamines; Hippocampus; In Vitro Techniques; Male; Nitroso Compounds; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Ouabain; Potassium Chloride; Rats; Rats, Wistar; Reserpine; S-Nitrosothiols; Sodium; Symporters; Thiophenes; Tritium

2001
Species specificity of amidine-based urokinase inhibitors.
    Biochemistry, 2001, Aug-07, Volume: 40, Issue:31

    Topics: Amidines; Amiloride; Amino Acid Sequence; Animals; Antineoplastic Agents; Binding Sites; Blood Proteins; Carcinoma, Lewis Lung; Crystallography, X-Ray; Humans; Mice; Molecular Sequence Data; Naphthalenes; Sequence Alignment; Sequence Homology, Amino Acid; Serine Proteinase Inhibitors; Species Specificity; Thiophenes; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

2001
Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:6

    Topics: Administration, Topical; Amiloride; Animals; Antihypertensive Agents; Aqueous Humor; Bumetanide; Diuretics; Electrophysiology; Female; Intraocular Pressure; Male; Mice; Sodium-Hydrogen Exchangers; Sulfonamides; Thiophenes

2002
Growth factors improve the in vivo migration of human skeletal myoblasts by modulating their endogenous proteolytic activity.
    Transplantation, 2004, Jun-15, Volume: 77, Issue:11

    Topics: Amiloride; Cell Membrane; Cell Movement; Cells, Cultured; Fibroblast Growth Factor 2; Humans; Insulin-Like Growth Factor I; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Muscle, Skeletal; Myoblasts; Peptide Hydrolases; Phenylalanine; Plasminogen Activator Inhibitor 1; Protease Inhibitors; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Serine Proteinase Inhibitors; Thiophenes; Tissue Distribution; Transcription Factors; Urokinase-Type Plasminogen Activator

2004
AT2 receptor non-peptide agonist C21 promotes natriuresis in obese Zucker rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:6

    Topics: Amiloride; Angiotensin II Type 1 Receptor Blockers; Animals; Bendroflumethiazide; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Sodium Channels; Imidazoles; Male; Natriuresis; Natriuretic Agents; Obesity; Pyridines; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Sodium; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Sulfonamides; Thiophenes; Urination

2012