amiloride has been researched along with pyrazines in 485 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 470 (96.91) | 18.7374 |
| 1990's | 8 (1.65) | 18.2507 |
| 2000's | 3 (0.62) | 29.6817 |
| 2010's | 4 (0.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benos, DJ; Cala, PM; Mandel, LJ; Simon, SA | 1 |
| Cuthbert, AW | 3 |
| Aickin, CC; Thomas, RC | 1 |
| Cuthbert, A; Cuthbert, AW | 1 |
| Kanto, J; Lammintausta, R; Mäntylä, R | 2 |
| Hulter, HN; Licht, JH; Sebastian, A | 1 |
| Arruda, JA; Kurtzman, NA; Mehta, PK; Sodhi, B | 1 |
| Husted, RF; Steinmetz, PR | 1 |
| Cuthbert, AW; Edwardson, JM | 2 |
| Mikkelsen, E; Pedersen, OL | 2 |
| Kristensen, P | 1 |
| Beauwens, R; Crabbé, J; Noé, G | 1 |
| Balaban, RS; Benos, DJ; Mandel, LJ | 2 |
| Brodsky, WA; Wilczewski, T | 1 |
| Meng, K | 2 |
| Knauf, H; Simon, B; Wais, U | 1 |
| Frizzell, RA; Gottlieb, GP; Schultz, SG; Turnheim, K | 1 |
| Emilio, MG; Menano, HP | 1 |
| Cuthbert, AW; Shum, WK | 5 |
| Goodman, DB; Lien, EL; Rasmussen, H | 1 |
| Knauf, H; Schollmeyer, P; Steinhardt, HJ | 1 |
| Lumholtz, IB | 1 |
| Benos, DJ; Mandel, LJ | 1 |
| Candia, OA | 1 |
| Arnow, J; Bowman, RH; Weiner, IM | 1 |
| Tomlinson, RW; Wood, AW | 1 |
| Bonaduce, D; D'Ascia, C; Ferrara, N; Petretta, M; Rengo, F; Saccá, L; Trimarco, B | 1 |
| Aceves, J; Cuthbert, AW; Edwardson, JM | 2 |
| Aceves, J; Cuthbert, AW | 1 |
| Nielsen, R | 3 |
| Lederballe Pedersen, O | 1 |
| Salvatore, C; Schena, FP; Vox, E | 1 |
| Castenfors, H | 2 |
| Amadeo, A; Currò, F; de Pasquale, C | 1 |
| Boddy, K; Brown, JJ; Davies, DL; Fraser, R; Kremer, D; Lever, AF; Morton, JJ; Robertson, JI | 2 |
| Overlack, A; Stumpe, KO | 1 |
| Evsikov, EM; Kharchenko, VI; Sidorenko, BA | 1 |
| Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE; Shelton, J | 1 |
| Eisalo, A; Kohvakka, A; Manninen, V | 1 |
| Simpson, FO; Waal-Manning, HJ | 1 |
| Berg, KJ | 1 |
| Festen, CM; Slegers, JF | 1 |
| de Sousa, RC; Li, JH | 2 |
| Bochner, F; McLaran, CJ; Whiting, GF | 1 |
| Gunther, RA; Rabinowitz, L; Sarason, RL | 1 |
| Devane, J; Ryan, MP | 4 |
| Counihan, TB; Dunne, A; Ryan, MF; Ryan, MP | 1 |
| Ambrosioni, E; Magnani, B; Melandri, G; Pasetti, L; Tartagni, F | 1 |
| Boulpaep, EL; O'Neil, RG | 1 |
| Bergis, K | 1 |
| Costa, R; Helou, CM; Leãg, MI; Magaldi, JB; Rocha, AD | 1 |
| Khoyi, MA; Pousti, A | 1 |
| Aroldi, A; Brancaccio, D; Cantaluppi, A; Cecchettin, M; Galmozzi, C; Graziani, G; Mioni, G; Ponticelli, C; Surian, M | 1 |
| Bernardi, P; Bobba, P; Croce, L; Dalla Torre, M; Di Benedetto, A; Galassi, A; Lombardo, M; Masacci, E; Montemartini, C; Mussari, A; Ricciardi, S; Santucci, F | 1 |
| Frömter, E; Gebler, B | 1 |
| Horne, WC; Simons, ER | 1 |
| Biggers, JD; Borland, RM; Powers, RD | 1 |
| Dewailly, P; Heim, J; Jaillard, J | 1 |
| Contini, C; Garberoglio, B; Giusti, C; Pauletti, M; Strata, G | 1 |
| Katz, U | 1 |
| Banks, RO; Kleinman, LI | 1 |
| Frizzell, RA; Schultz, SG; Turnheim, K | 2 |
| Cuthbert, AW; Fanelli, GM | 1 |
| Chappin, JJ; Henquet, JW; Hintzen, AH; Slagboom, G | 1 |
| Brodsky, WA; Durham, J; Ehrenspeck, G | 1 |
| Frizzell, RA; Turnheim, K | 1 |
| Burkinshaw, L; Davidson, C; Morgan, DB | 1 |
| Taub, M | 1 |
| McSorley, P; Mohamed, F; Warren, DJ | 1 |
| Cereijido, M; Rabito, CA; Rotunno, CA | 1 |
| Dawson, DC; Thompson, SM | 1 |
| Segre, G; Tilser, I | 1 |
| Alberti, E; Alessi, A; Antognetti, R; Baraldini, L; Bastagli, L; Bellomo, G; Bernardi, P; Buscarini, L; Camarri, E; Camerini, F; Cazzin, R; Dal Canton, A; De Piccoli, B; Del Favero, A; Fontana, G; Forattini, C; Furlanello, F; Giorgi-Pierfranceschi, D; Lechi, A; Lenzi, S; Malamani, V; Migone, L; Nava, S; Pallumeri, E; Passeri, M; Pecoraro, F; Perin, S; Piccolo, E; Scardi, S; Scarpioni, L; Vergara, G | 1 |
| Antcliff, AC; Beevers, DG; Hamilton, M; Pearce, VR | 1 |
| Benvenuti, C; Sanguigni, D | 1 |
| Corvol, P; Milliez, P; Thibonnier, M | 1 |
| Baumann, JC; Braun, HD | 1 |
| Brailovsky, D | 1 |
| Agabiti-Rosei, E; Alicandri, C; Ambrosioni, E; Magnani, B; Miele, N; Muiesan, G | 1 |
| Essig, A; Hong, CD | 1 |
| Hjelt, K; Rask-Madsen, J | 1 |
| Biber, TU; Mullen, TL | 1 |
| Bentivoglio, M; Boschetti, E; Dottorini, M; Grassi, V; Losito, A; Muiesan, G | 1 |
| Hoshi, T; Sudou, K | 1 |
| Bielecki, A; Piwowarska, W | 1 |
| Greenwald, LE; Kirschner, LB | 1 |
| Juhos, E; Radó, JP; Sawinsky, I | 1 |
| Barratt, LJ | 1 |
| Helman, SI; O'Neil, R | 1 |
| Juhos, E; Radó, JP | 1 |
| Burge, PS; Montuschi, E | 1 |
| Wong, PY; Yeung, CH | 1 |
| Gee, JD | 1 |
| Danĕková, H; Dzúrik, R; Fedelesová, V; Hlavatá, E | 1 |
| Vorburger, C | 1 |
| Adornato, E; Tassone, F | 1 |
| Albiez, G; Knauf, H; Lübcke, R; Wais, U | 1 |
| Bianchi Porre, G; Lazzaroni, M; Petrillo, M | 1 |
| Bergström, J | 1 |
| Cleres-Kaiser, I | 1 |
| Cohen, L; Kitzes, R; Rosenfeld, J | 1 |
| Sitprija, V; Stianrapapongs, P | 1 |
| Banach, S; Greco, J; Seller, RH; Seth, R | 1 |
| Jounela, A; Pyörälä, K | 1 |
| Danĕková, H; Dzúrik, R; Hlavatá, E | 1 |
| Rasmussen, K | 1 |
| Greeff, K; Köhler, E | 1 |
| Plant, C; Venanzi, CA; Venanzi, TJ | 1 |
| Bertrand, WS; Morrison, AR; Ross, WR | 1 |
| Beyer, KH; Gelarden, RT; Vesell, ES | 1 |
| Chen, MC; Cragoe, EJ; Daniel, EE; Gaspar, V; Kwan, CY; Ohta, A; Shi, AG; Wang, ZL | 1 |
| Giles, RE; Halterman, TJ; Howe, BB; Johnston, PA; Kau, ST; Leszczynska, K; Li, JH; Schwartz, JA; Yochim, CL; Zuzack, JS | 1 |
| Johnston, PA; Kau, ST | 1 |
| Abramcheck, FJ; Helman, SI; Van Driessche, W | 1 |
| DeSimone, JA; Ferrell, F | 1 |
| Wingo, CS | 1 |
| Eaton, DC; Hamilton, KL | 1 |
| Hill, JA; Marchese, AC; Strauss, HC; Xie, PD | 1 |
| Barros, F; Cragoe, EJ; Dethmers, JK; Kaczorowski, GJ; Trumble, MJ | 1 |
| Cragoe, EJ; Li, JH; Lindemann, B | 1 |
| Lindsay, RM; Spence, JD; Wong, DG | 1 |
| Besterman, JM; Cragoe, EJ; Cuatrecasas, P; LeVine, H; May, WS | 1 |
| Czech, MP; Davis, RJ | 1 |
| Adelberg, EA; Cragoe, EJ; Haggerty, JG; Slayman, CW | 1 |
| Alpern, RJ; Howlin, KJ; Rector, FC | 1 |
| Mochizuki-Oda, N; Oosawa, F | 1 |
| Bastie, MJ; Creach, Y; Dufresne, M; Hollande, E; Ribet, A; Vaysse, N | 1 |
| Günther, T; Vormann, J | 1 |
| Bour, TC; Hill, DL | 1 |
| Beyer, KH; Gelarden, RT | 1 |
| Blaine, EH; Bock, MG; Cragoe, EJ; Smith, RL | 1 |
| Brachfeld, J; Itskovitz, H; Lunn, JA; Maxwell, MH; Moser, M; Zawada, ET | 1 |
| Larochelle, P; Logan, AG | 1 |
| Alon, U; Chan, JC | 2 |
| Cortright, RN; DeLisle, RC; Douglas, JG; Hopfer, U; Will, PC | 1 |
| Cortright, RN; Groseclose, RG; Hopfer, U; Will, PC | 1 |
| Batlle, DC; Gaviria, M; Grupp, M; von Riotte, AB | 1 |
| Dzúrik, R; Dzúriková, V; Krechnáková, A; Szalayová, V | 1 |
| Arnold, WS; Dewell, WM; Maddox, RW | 1 |
| Knauf, H; Mutschler, E; Reuter, K | 2 |
| Bühring, KU; Leopold, G; Pabst, J; Simane, Z; Ungethüm, W | 1 |
| Anderson, L; Cragoe, EJ; Schellenberg, GD; Swanson, PD | 1 |
| Bertoni-Freddari, C; Giuli, C; Muzzioli, M; Pieri, C | 1 |
| Brand, JG; Silver, WL; Teeter, JH | 1 |
| Bennett, WM; Houghton, DC; Porter, GA; Purnell, J | 1 |
| Ferrara, LA; Gagliardi, R; Mancini, M; Scillitani, A; Strazzullo, P | 1 |
| Midelfart, A; Ratkje, SK | 1 |
| Fabre, J; Pinon, JF | 1 |
| Breckenridge, AM; Dollery, CT; George, CF | 1 |
| De Santo, NG; Doerken, U; Ebel, H; Ehrich, J | 1 |
| Nash, DT | 1 |
| Alberti, KG; Aynsley-Green, A | 2 |
| Fülgraff, G; Gulden, WD; Rudroff, WD | 1 |
| Beevers, DG; Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Kremer, D; Lever, AF; Robertson, JI | 1 |
| Ilett, KF; Lockett, MF | 1 |
| Cuthbert, AW; Maetz, J | 1 |
| Singer, MA | 1 |
| Degaute, JP; Demanet, JC; Fichefet, JP; Hubert, C; Paduart, P | 1 |
| Ensor, DM | 1 |
| Gerbaux, A; Hiltgen, M; Renais, J; Scebat, L | 1 |
| Lüderitz, B; Steinbeck, G; Tiedemann, W | 1 |
| Brummer, P | 1 |
| Martínez, AM; Martínez, JR | 1 |
| Greenwald, L; Kerstetter, TH; Kirschner, LB | 1 |
| Carrasquer, G; Dinno, MA; Fravert, DG; Olson, AK; Schwartz, M | 1 |
| Hintzen, AH | 1 |
| Bertrand, ME; Warembourg, H | 1 |
| Chapelle, M; Chiche, P | 1 |
| Demanet, JC; Hubert, C; Sevens-Rocmans, C | 1 |
| Sanna, GP | 1 |
| Bianchi Porro, G; Petrillo, M | 1 |
| Kennedy, RD; MacFarlane, JP | 1 |
| Bertrand, ME; Ginestet, A; Warembourg, H | 1 |
| Cox, JR; Porthouse, A | 1 |
| Handler, JS; Orloff, J; Preston, AS | 1 |
| Cuthbert, AW; Wong, PY | 3 |
| Ellison, AC; Maren, TH | 1 |
| Bancons, J; Dubarry, JJ; Quinton, A | 1 |
| Blatrix, C | 1 |
| Aceves, J; Cereijido, M | 1 |
| Brown, JJ; Davies, DL; Fraser, R; Kremer, D; Lever, AF; Robertson, JI | 1 |
| Davidson, C; Gillebrand, IM | 1 |
| Hohenegger, M | 2 |
| Falase, AO; Salako, LA | 1 |
| Naidoo, DN; Seedat, YK | 1 |
| Layton, WM; Storch, TG | 1 |
| Goulding, A; Irvine, RO; Jukes, C | 1 |
| Schulz, I; Wizemann, V | 1 |
| Bechtler, H; Taugner, R | 1 |
| Smith, AJ; Smith, RN | 1 |
| Kaiser, I | 1 |
| Carrasquer, G; Olson, AK; Wilczewski, TW | 1 |
| Carrasquer, G; Fravert, DG; Olson, AK | 1 |
| Gutsche, U; Hegel, U; Lange, S; Veit, C | 2 |
| Bain, WH; Hocking, MA | 1 |
| Burg, MB; Orloff, J; Stoner, LC | 1 |
| Herrera, FC | 1 |
| Schluz, I; Wizemann, V | 1 |
| Croxson, MS; John, MB; Neutze, JM | 1 |
| Antcliff, AC; Beevers, DG; Hamilton, M; Harpur, JE | 2 |
| Meyer, P; Milliez, P | 1 |
| Baer, JE; Goldman, WJ; Mattis, PA; Scott, W; Skeggs, HR | 1 |
| Hohenegger, M; Marktl, W; Selzer, H | 1 |
| Savoie, LL | 1 |
| Blascheck, JA; Gardell, C; Kovács, K | 1 |
| Covelli, I; Frati, L; Mozzi, R; Rossi, R | 1 |
| Grayson, MF; Smith, AJ; Smith, RN | 1 |
| Frelin, C; Lazdunski, M; Vigne, P | 3 |
| Furuya, W; Grinstein, S | 1 |
| Benos, DJ; Sapirstein, VS | 2 |
| Furuya, W; Gelfand, EW; Goetz, JD; Grinstein, S; Rothstein, A | 1 |
| Doucet, A; Mernissi, GE | 1 |
| Palmer, LG | 1 |
| Cassel, D; Cragoe, EJ; Glaser, L; Shaikewitz, T; Zhuang, Y | 1 |
| Charney, AN; Kurtin, P | 1 |
| Cragoe, EJ; Labelle, EF; Woodard, PL | 1 |
| Costa, CJ; Cragoe, EJ; Kirschner, LB | 1 |
| Alles, WP; Binder, HJ; Sandle, GI; Wills, NK | 1 |
| Audinot, M; Borsotto, M; Cragoe, EJ; Frelin, C; Lazdunski, M; Vigne, P | 1 |
| Benos, DJ; Olans, L; Sariban-Sohraby, S | 1 |
| Al-Bazzaz, FJ; Zevin, R | 1 |
| Garty, H | 1 |
| Franz, IW | 1 |
| Kakác, B; Matousová, O; Peterková, M | 1 |
| Albertazzi, A; Cappelli, P; Del Rosso, G; Di Paolo, B; Di Vito, R; Palmieri, PF; Spisni, C | 1 |
| Jaffey, L; Martin, A | 1 |
| Auvinen, J; Gordin, A; Saraste, K; Seppälä, T; Tarkiainen, A | 1 |
| Cornell, JC | 1 |
| Fehlmann, M; Freychet, P; Koch, KS; Leffert, HL; Samson, M | 2 |
| Bonting, SL; De Pont, JJ; Fleuren-Jakobs, AM; Kuijpers, GA; Rodrigues de Miranda, JF; Van Nooy, IG | 1 |
| Besterman, JM; Cragoe, EJ; Cuatrecasas, P; Tyrey, SJ | 1 |
| Banderali, G; Carnovali, M; Crespi, E; Missaglia, A; Ponti, GB | 1 |
| Hilewitz, H; Rogel, S; Weinstein, M | 1 |
| Baskerville, FB; Howell, JR; Huf, EG | 1 |
| Saier, MH; Taub, M | 1 |
| Molski, TF; Naccache, PH; Sha'afi, RI | 1 |
| Labelle, EF; Lee, SO | 2 |
| Cortright, RN; DeLisle, RC; Hopfer, U; Will, PC | 1 |
| McQuillan, J; Ralph, RK; Smart, J; Wojcik, SJ | 1 |
| Hopfer, U; Legris, GJ; Will, PC | 1 |
| Van Driessche, W; Wills, NK; Zeiske, W | 1 |
| Cremaschi, D; Meyer, G | 1 |
| Chambard, JC; Franchi, A; Paris, S; Pouysségur, J; Van Obberghen-Schilling, E | 1 |
| Auberger, P; Le Cam, A; Samson, M | 1 |
| Bentley, PJ; McGahan, MC | 1 |
| Hillyard, SD; Van Driessche, W; Zeiske, W | 1 |
| Cahn, F; Coutermarsh, BA; Lubin, M | 1 |
| Briggman, JV; Jenkins, MQ; Patton, CJ; Spicer, SS | 1 |
| Bacaner, MB; Ilani, A; Lichtstein, D | 1 |
| Bessonov, BI; Butsuk, SV | 1 |
| Hardie, DG; Holland, R; Woodgett, JR | 1 |
| Paris, S; Pouysségur, J | 1 |
| Cassel, D; Glaser, L; Rothenberg, P; Schlesinger, P | 1 |
| Mandel, LJ; Soltoff, SP | 1 |
| Burckhardt, G; Sabolić, I | 1 |
| Briggman, JV; Cragoe, EJ; Graves, JS; Spicer, SS | 1 |
| Frehland, E; Hoshiko, T; Machlup, S | 1 |
| Edelman, IS; Garty, H | 1 |
| Eaton, DC; LaBelle, EF | 1 |
| Griffing, GT; Melby, JC | 1 |
| Natochin, IuV; Reznik, LV | 1 |
| Ives, HE; Warnock, DG; Yee, VJ | 1 |
| Li, JH; Lindemann, B | 1 |
| Cragoe, EJ; Frelin, C; Lazdunski, M; Vigne, P | 2 |
| LaBelle, EF | 1 |
| Cameron, IL; Cragoe, EJ; Lum, JB | 1 |
| Cragoe, E; Franchi, A; L'Allemain, G; Pouysségur, J | 1 |
| Arias, IM; Forgac, M | 1 |
| Bessonov, BI; Klyshta, MD; Korkushko, AO; Kryshtal', OA | 1 |
| Frelin, C; Lazdunski, M; Sauvaigo, S; Vigne, P | 1 |
| Besterman, JM; Cuatrecasas, P | 1 |
| Korkushko, AO; Kryshtal', OA | 1 |
| Goetz, JD; Grinstein, S; Rothstein, A | 2 |
| Harvey, BJ; Kernan, RP | 2 |
| Kremer, D | 1 |
| Albanesi, FM; Cantarelli, EL; da Cunha, GP; Wajngarten, M | 1 |
| Cepelák, V; Mayer, O; Suchová, H | 1 |
| Bolzano, K; Krempler, F; Sandhofer, F | 1 |
| Cumming, AM; Fraser, R; Leckie, B; Mason, P; Millar, JA; Robertson, JI | 1 |
| Lehtonen, A; Lindroos, M | 1 |
| Dean, S; Spencer-Mills, L | 1 |
| Aboulafia, J; Lacaz-Vieira, F; Sanioto, SM | 1 |
| Thomas, JP; Thomson, WH | 1 |
| Aylett, MJ | 1 |
| Hutchinson, CE; Jong, M; Matthews, K; Zalin, AM | 1 |
| Altschuld, RA; Brierley, GP; Hohl, CM; Lamka, KG | 1 |
| Borland, C; Davison, W; Millson, D; Murphy, P | 1 |
| Eastell, R; Edmonds, CJ | 1 |
| Javaheri, S; Weyne, J | 1 |
| Barr, J; Chan, L; Maronde, RF; Spencer, CA; Vlachakis, ND | 1 |
| Cabili, S; Ophir, J; Ophir, O | 1 |
| Giunta, S; Groppa, G; Pieri, C | 1 |
| Brdová, L; Strec, V; Valusková, H | 1 |
| Cameron, IL; Hunter, KE | 2 |
| Currie, WJ; Isitt, VL; VandenBurg, MJ; Young, JH | 1 |
| Arr, SM; Wight, L; Woollard, ML; Young, JH | 1 |
| Floreani, M; Luciani, S | 1 |
| Bertoni-Freddari, C; Giuli, C; Lustyik, G; Pieri, C | 1 |
| Ryan, MP | 1 |
| Alon, U; Chan, JC; Costanzo, LS | 1 |
| Carretero, OA; Diaz, MA; Scicli, AG | 1 |
| Lockhead, E; Maes, FW; Schiffman, SS | 1 |
| Carlson, J; Cragoe, E; Dorey, F; Koeffler, HP | 1 |
| Cragoe, EJ; Kaczorowski, GJ; Siegl, PK; Trumble, MJ | 1 |
| Benos, DJ; Hyde, BA; Latorre, R | 1 |
| Godal, T; Heikkilä, R; Iversen, JG | 1 |
| Benos, DJ; Reyes, J; Shoemaker, DG | 1 |
| Dige-Petersen, H; Giese, J; Ibsen, H; Leth, A; Nielsen, MD; Rasmussen, S; Svendsen, UG | 1 |
| Browne, R; Hill, K; Leppla, D; Pak, CY | 1 |
| Betz, AL | 1 |
| Bijman, J; Cook, DI; van Os, CH | 1 |
| Altschuld, RA; Brierley, GP; Cragoe, EJ; Jurkowitz, MS | 1 |
| Carney, DH; LaBelle, EF; Stiernberg, J | 1 |
| Obel, AO | 1 |
| Schneider, H | 1 |
| Deetjen, P; Lang, F; Messner, G; Oberleithner, H; Wang, W | 1 |
| Ferrara, LA; Galletti, F; Siani, A; Strazzullo, P | 1 |
| Bentivoglio, M; Corea, L; Verdecchia, P | 1 |
| Galli, F; Piazza, V; Salvadeo, A; Segagni, S; Villa, G | 1 |
| Agrawal, N; Akdamar, K; Ertan, A; McMahon, FG; Ryan, JR | 1 |
| DeSimone, JA; Heck, GL; Mierson, S | 1 |
| LaBelle, EF; Rex, KA; Sordahl, LA | 1 |
| Edmonds, CJ; Mackenzie, J | 1 |
| Cooper, WD; Currie, WJ; Vandenburg, MJ | 1 |
| Stokes, JB | 1 |
| Curtis, LN; Misch, DW | 1 |
| Casale, A; Comolli, R; Mariotti, D | 1 |
| Coates, PE; Thiessen, JJ; Yip, MS | 1 |
| Morse, BM; Stern, RS; Strykers, PH | 1 |
| Costanzo, LS | 1 |
| Andersson, PO; H-Andersen, H; Hagman, A; Henning, R | 1 |
| Gordon, LG | 1 |
| Knauf, H; Steim, H | 1 |
| Crabbé, J | 1 |
| LaBelle, EF; Valentine, ME | 1 |
| Chao, J; Margolius, HS | 1 |
| Eggena, P; Gibas, A | 1 |
| Odlind, B | 1 |
| Hulter, HN; Ilnicki, LP; Licht, JH; Sebastian, A | 1 |
| Villereal, ML | 2 |
| Higgins, JT; Thurman, CL | 1 |
| Bertoni-Freddari, C; Giuli, C; Giunta, S; Muzzioli, M; Pieri, C | 1 |
| Gould, BA; Hornung, RS; Kieso, H; Raftery, EB | 2 |
| Arr, S; Parry, EE; Tait, D | 1 |
| Cameron, IL; Pool, TB; Smith, NK; Sparks, RL | 1 |
| Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND | 1 |
| Hoshi, T; Kawahara, K; Sakai, T | 1 |
| Khorunzhaia, LV; Merzon, KA; Tsoĭ, AN | 1 |
| Mor, R; Pitlik, S; Rosenfeld, JB | 1 |
| Brown, JL; Chrysant, SG; Hagstrom, D | 1 |
| Dubinsky, WP; Frizzell, RA | 1 |
| Cragoe, E; O'Donnell, ME; Villereal, ML | 1 |
| Frederiksen, O | 1 |
| Anderson, L; Schellenberg, GD; Swanson, PD | 1 |
| Cantley, L; Housman, D; Levenson, R | 1 |
| Benos, DJ; Mandel, LJ; Simon, SA | 1 |
| Benos, DJ; Watthey, JW | 1 |
| Hayashi, H; Takada, M | 1 |
| Drayer, JI; Hoefnagels, WH; Kloppenborg, PW; Smals, AG | 1 |
| Kurtzman, NA | 1 |
| Affrime, MB; Gould, A; Lowenthal, DT; Mazzella, J; Onesti, G; Shirk, J; Walker, F | 1 |
| van Soeren, F | 1 |
| Burns, DG; Pittaway, D | 1 |
| Pittaway, D | 1 |
| Boquist, L | 1 |
| Andersson, PO; Henning, R; Karlberg, BE; Lins, LE; Nilsson, OR; Odar-Cederlöf, I; Tolagen, K | 1 |
| Gillies, A; Morgan, TO; Myers, JB; Waga, S | 1 |
| Hwang, IK; Moncloa, F; Muccilli, AC | 1 |
| Baron, JH; Gribble, RJ; Holdstock, DJ; Lewis, SI; Murgatroyd, RE; Reed, PI; Vincent-Brown, A | 1 |
| Huikko, M; Varjoranta, K; Viherkoski, M | 1 |
| Leary, WP; Reyes, AJ | 1 |
| Nordlie, KE; Søiland, C | 1 |
| Ballo, M; Cospite, M; Ferrara, F; Lo Presti, T; Meli, F; Milio, G; Raimondi, F | 1 |
| Olesen, OV; Thomsen, K | 1 |
| Benos, DJ | 1 |
| El Mahadi Bella, M; El Zein, O; Khalil, SI | 1 |
| Campbell, N; Fernandez, PG; Galway, AB; Gill, V; Granter-Button, S; Kim, BK; MacDonald, J; Sharma, JN; Snedden, W | 1 |
| Aurecchia, SA; Cole, AG; Griffing, GT; Komanicky, P; Melby, JC; Sindler, BH | 1 |
| McInnes, GT | 1 |
| Bindslev, N; Cuthbert, AW; Edwardson, JM; Skadhauge, E | 1 |
| Davis, CW; Finn, AL | 1 |
| Aurecchia, SA; Griffing, GT; Komanicky, P; Melby, JC; Sindler, BH | 1 |
| Cameron, IL; Cragoe, EJ; Hunter, KE | 1 |
| Grimshaw, JJ; Jaffé, G; Vallé-Jones, JC; Warnock, JM | 1 |
| Bjaeldager, P; Garsdal, P; Kampmann, JP; Svendsen, TL | 1 |
| Konishi, T; Salt, AN | 1 |
| Estep, JA; Marin, MG; Zorn, JP | 1 |
| Salonen, JT; Ylitalo, P | 1 |
| Fehlmann, M; Heiser, W; Koch, KS; Lad, PJ; Leffert, HL; Skelly, H | 1 |
| O'Donnell, ME; Villereal, ML | 1 |
| Cobb, MH; Scott, WN | 1 |
| Lee, WM; Tsang, AY; Wong, PY | 1 |
| Della Marchina, MM; Renzi, G; Serofilli, S | 1 |
| Boehringer, K; Meier, A; Mordasini, R; Riesen, W; Schiffl, H; Weidmann, P | 1 |
| Buch, J; Egeblad, H; Hansen, PB; Kjaergård, H; Steiness, E; Waldorff, S | 1 |
| Cuthbert, AW; Edwardson, JM; Ellory, JC; Fanestil, DD | 1 |
| Akhtar-Khavari, F; Khoyi, MA; Rezaei, E | 1 |
| Anderson, PO; Colvin, CL; Macfie, HL | 1 |
| Perry, SF; Randall, DJ | 1 |
| Edmonds, CJ | 1 |
| Aroldi, A; Colussi, G; D'Angelo, A; Fabris, A; Graziani, G; Mandressi, A; Maschio, G; Minetti, L; Pagano, F; Ponticelli, C; Rocco, F; Surian, M; Tasca, A; Tessitore, N; Trinchieri, A | 1 |
| Ambrosioni, E; Bassein, L; Lusa, AM; Magnani, B; Tartagni, F | 1 |
| Besseghir, K; Rennick, B | 1 |
| Enenkel, W; Nobis, H; Pollak, H; Prachar, H | 1 |
| Graves, JS; Krall, AR; Pressley, TA | 1 |
| Aronson, PS; Kinsella, JL | 1 |
| Ceccarelli, S; Charney, AN; Costenbader, CL; Donowitz, M; Wallach, J | 1 |
| Jensen, HA; Olsen, ME | 1 |
| Grasl, M; Luger, A; Turnheim, K | 1 |
| Barrera, E; Barrera, LA; Creparula, R; Gotlieb, D; Pertzov, G; Prigollini, D; Yeyati, NL | 1 |
| Tarssanen, L | 1 |
| Albanesi Filho, FM; Brandão, AP; Oigman, W | 1 |
| Arruda, JA; Dytko, G; Kurtzman, NA; Mola, R; Subbarayudu, K | 1 |
| George, CF | 1 |
| Danĕková, H; Dzúrik, R; Fedelesová, V | 1 |
| Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE | 1 |
| Glynn, RD; Hulter, HN; Ilnicki, LP; Licht, JH; Sebastian, A | 1 |
| Pedersen, TR | 1 |
| Ahokas, JT; Emmerson, BT; Hall, GR; Ravenscroft, PJ; Tobert, JA | 1 |
| Frewin, DB; Penhall, RK | 1 |
| Alcazar, JM; Diaz, VP; Jarillo, MD; Millet, VG; Rodicio, JL; Ruilope, L | 1 |
| Rosenfeld, JB | 1 |
| Lye, MD; Wan, HH | 1 |
| Okrasinski, H | 1 |
| Feuerstein, G; Hemmendinger, R; Lichtenberg, D; Zilberman, Y | 1 |
| Dearborn, DG; Hopfer, U; Lebowitz, JL; Taylor, A; Will, PC | 1 |
| Luger, A; Turnheim, K | 1 |
| Huikko, M; Rossi, M; Tarssanen, L | 1 |
| Dytko, G; Kinter, LB; Smith, PL | 1 |
| Ellis-Davies, GC; Kaplan, JH; Kleyman, TR | 1 |
| Ache, BW; Bobkov, YV | 1 |
| Bilodeau, MT; Bock, MG; Cato, MJ; Chang, RK; Cook, SP; Di Marco, CN; Dipardo, RM; Hartman, GD; Jovanovska, A; Kane, SA; Kuduk, SD; Leitl, M; Spencer, RH; Urban, MO | 1 |
| Kichko, TI; Reeh, PW | 1 |
| Beckmann, N; Blé, FX; Cannet, C; Collingwood, S; Danahay, H | 1 |
| Alijevic, O; Boillat, A; Kellenberger, S | 1 |
| Abraham, WM; Baettig, U; Collingwood, SP; Coote, KJ; Czarnecki, S; Danahay, H; Ethell, B; Faller, T; Gosling, M; Groot-Kormelink, PJ; Harris, J; Lock, R; Paisley, D; Poll, CT; Sabater, J; Schumacher, A; Smith, NJ; Sugar, R; Tweed, M; Vyas, M; Watson, H; Williams, G; Young, A | 1 |
| Fischer, MJM; Namer, B; Reeh, PW; Schwarz, MG | 1 |
3 review(s) available for amiloride and pyrazines
| Article | Year |
|---|---|
[Importance of the continuity of anti-hypertension treatment in prevention of ischemic cardiovascular diseases: preliminary note. Controlled study of hypertensive patients treated with amiloride associated with hydrochlorothiazide and chlorthalidone].
Topics: Adult; Aged; Amiloride; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines | 1978 |
"Short-circuit" renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Amiloride; Animals; Bicarbonates; Chlorides; Digoxin; Hypokalemia; Lithium; Phosphates; Pyrazines; Rats | 1980 |
Amiloride: a molecular probe of sodium transport in tissues and cells.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Calcium; Depression, Chemical; Diuretics; Dose-Response Relationship, Drug; Epithelium; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Potassium; Pyrazines; Skin; Sodium; Turtles; Urinary Bladder | 1982 |
70 trial(s) available for amiloride and pyrazines
| Article | Year |
|---|---|
Urinary electrolyte profiles after amiloride, hydrochlorthiazide and the combination.
Topics: Adolescent; Adult; Amiloride; Chlorides; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Male; Placebos; Potassium; Pyrazines; Sodium; Urination | 1978 |
Beta-blockers and uric-acid excretion.
Topics: Amiloride; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol; Uric Acid | 1978 |
[Treatment of mild to moderate essential arterial hypertension with timolol alone and in combination with hydrochlorothiazide + amiloride. A multicenter, double-blind, cross-over study].
Topics: Amiloride; Clinical Trials as Topic; Creatinine; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Placebos; Potassium; Propanolamines; Pyrazines; Timolol | 1977 |
[Effects of a potassium-sparing diuretic in cardiac edema and ascitic cirrhosis].
Topics: Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Edema; Female; Heart Diseases; Humans; Hydrochlorothiazide; Liver Cirrhosis; Male; Middle Aged; Pyrazines | 1977 |
Long term effect of timolol and hydrochlorothiazide, or hydrochlorothiazide and amiloride, in essential hypertension.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propanolamines; Pulse; Pyrazines; Time Factors; Timolol | 1977 |
Amiloride in the treatment of primary hyperaldosteronism and essential hypertension.
Topics: Adult; Amiloride; Blood Pressure; Clinical Trials as Topic; Electrolytes; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Pyrazines | 1978 |
[Antihypertensive effect of a fixed beta-receptor blockader-diuretic combination during a single daily administration].
Topics: Adult; Amiloride; Clinical Trials as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Placebos; Propanolamines; Pyrazines; Timolol | 1978 |
[Therapeutic use of amiloride and its combinations with hydrochlorothiazide and furosemide in chronic circulatory insufficiency].
Topics: Adult; Aged; Amiloride; Cardiovascular Diseases; Chronic Disease; Clinical Trials as Topic; Diuresis; Drug Combinations; Drug Evaluation; Drug Synergism; Female; Furosemide; Humans; Hydrochlorothiazide; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Time Factors | 1978 |
The relative potency of amiloride and spironolactone in bendrofluazide-treated hypertensive patients [proceedings].
Topics: Amiloride; Bendroflumethiazide; Clinical Trials as Topic; Humans; Hypertension; Pyrazines; Spironolactone | 1978 |
Maintenance of potassium balance during diuretic therapy.
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Potassium; Potassium Chloride; Pyrazines; Spironolactone; Triamterene | 1979 |
Individual factors influencing the response to a beta-adrenergic blocking agent given alone and in combination with a diuretic on arterial hypertension.
Topics: Adult; Aging; Amiloride; Body Weight; Clinical Trials as Topic; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Time Factors; Timolol | 1979 |
One year follow-up of hyperuricaemic hypertensive patients treated with tienilic acid or a diuretic with or without uric acid-lowering drugs.
Topics: Alkaline Phosphatase; Amiloride; Aspartate Aminotransferases; Bilirubin; Blood Pressure; Clinical Trials as Topic; Cyclopenthiazide; Diuretics; Female; Follow-Up Studies; Glycolates; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Pyrazines; Sodium Chloride Symporter Inhibitors; Ticrynafen; Uric Acid | 1979 |
The effects of potassium supplements, spironolactone of amiloride on the potassium status of patients with heart failure.
Topics: Adult; Aged; Amiloride; Female; Furosemide; Heart Failure; Humans; Male; Middle Aged; Potassium; Potassium Deficiency; Pyrazines; Spironolactone | 1978 |
Renin-aldosterone system and urinary electrolytes after amiloride, hydrochlorothiazide and the combination.
Topics: Adolescent; Adult; Aldosterone; Amiloride; Drug Combinations; Electrolytes; Female; Humans; Hydrochlorothiazide; Male; Pyrazines; Renin; Time Factors | 1978 |
[Potassium-saving saluretic treatment of hypertension and edematous heart decompensation with Moduretik].
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Edema, Cardiac; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines | 1976 |
The use of timolol maleate alone and with diuretic in the treatment of essential hypertension.
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Placebos; Potassium; Propanolamines; Pyrazines; Timolol | 1976 |
Evaluation of the effect of timolol alone and in combination with hydrochlorothiazide and amiloride in the treatment of mild to moderate arterial hypertension: a double-blind, controlled study.
Topics: Adult; Amiloride; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol | 1976 |
[The anti-hypertensive effect of timolol maleate (blocadren) in gradated combination with a diuretic].
Topics: Amiloride; Benzothiadiazines; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Sodium Chloride Symporter Inhibitors; Timolol | 1976 |
[Letter: Ascrtogenicliver cirrhosis. Effect of amiloride on water-electrolytemetabolsim].
Topics: Amiloride; Ascites; Chlorides; Clinical Trials as Topic; Furosemide; Humans; Hydrochlorothiazide; Hypokalemia; Hyponatremia; Liver Cirrhosis; Pyrazines; Water-Electrolyte Balance | 1975 |
The effect of hydrochlorothiazide and amiloride administered together on muscle electrolytes in normal subjects.
Topics: Adult; Amiloride; Biopsy; Chlorides; Clinical Trials as Topic; Drug Interactions; Humans; Hydrochlorothiazide; Magnesium; Muscles; Potassium; Pyrazines; Sodium; Water-Electrolyte Balance | 1975 |
[Treatment of cardiac and hepatic edemas using the potassium-sparing diuretic Moduretic].
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Edema; Female; Heart Diseases; Humans; Hydrochlorothiazide; Liver Diseases; Male; Middle Aged; Pyrazines | 1975 |
[Effect of combined treatment with hydrochlorothiazide and amiloride on serum and urinary potassium].
Topics: Amiloride; Clinical Trials as Topic; Drug Therapy, Combination; Heart Failure; Humans; Hydrochlorothiazide; Hypokalemia; Potassium; Pyrazines | 1975 |
Effects of triamterene and amiloride on urinary sediment in hypertensive patients taking hydrochlorothiazide.
Topics: Amiloride; Clinical Trials as Topic; Crystallization; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kidney Calculi; Male; Middle Aged; Nephritis, Interstitial; Pyrazines; Random Allocation; Triamterene | 1985 |
Blood pressure lowering and potassium conservation by triamterene-hydrochlorothiazide and amiloride-hydrochlorothiazide in hypertension.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Triamterene | 1985 |
Hydrochlorothiazide-amiloride versus hydrochlorothiazide alone for essential hypertension: effects on blood pressure and serum potassium level.
Topics: Adolescent; Adult; Age Factors; Aged; Amiloride; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pulse; Pyrazines; Random Allocation | 1985 |
[Esmaloride--a new potassium neutral diuretic combination. Clinical pharmacologic properties].
Topics: Aldosterone; Amiloride; Blood Glucose; Blood Pressure; Body Weight; Creatinine; Drug Combinations; Female; Heart Rate; Humans; Hypertension; Male; Potassium; Pyrazines; Trichlormethiazide; Triglycerides; Uric Acid; Water-Electrolyte Balance | 1985 |
Cross-over study of muzolimine and hydrochlorothiazide-amiloride in hypertensive patients.
Topics: Adult; Amiloride; Blood Pressure; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Muzolimine; Potassium; Pyrazines; Pyrazoles | 1985 |
Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia.
Topics: Adult; Aged; Amiloride; Blood Pressure; Body Weight; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Pyrazines; Sodium; Spironolactone; Time Factors; Urea | 1973 |
[Effect of amiloride on potassium loss induced by hydrochlorothiazide].
Topics: Amiloride; Chlorides; Diuresis; Drug Interactions; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Hypokalemia; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Statistics as Topic | 1974 |
The effects of amiloride during diuretic therapy in elderly subjects.
Topics: Administration, Oral; Aged; Amiloride; Calcium; Clinical Trials as Topic; Diuretics; Drug Combinations; Edema; Female; Humans; Hydrochlorothiazide; Hypokalemia; Male; Potassium; Pyrazines; Sodium; Urea; Uric Acid | 1972 |
[Treatment of cardiac edema with a new diuretic (combination of amiloride hydrochlorate and hydrochlorothiazide)].
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Diuretics; Drug Combinations; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Sodium | 1974 |
Amiloride hydrochloride combined with hydrochlorothiazide in the control of hypertension and plasma potassium levels.
Topics: Alanine Transaminase; Amiloride; Aspartate Aminotransferases; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Pyrazines; Urea; Uric Acid | 1972 |
[Treatment of the hypertensive patient. Value of Amiloride during saldiuretic treatment].
Topics: Adult; Amiloride; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Kidney Function Tests; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Spironolactone; Water-Electrolyte Balance | 1972 |
A controlled study of the antihypertensive effect of carteolol, a new beta-adrenergic receptor blocking drug, in combination with hydrochlorothiazide and amiloride.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Carteolol; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines | 1981 |
The therapeutic use of a new potassium-sparing diuretic, amiloride, and a converting enzyme inhibitor, MK-421, in preventing hypokalemia associated with primary and secondary hyperaldosteronism.
Topics: Adult; Aged; Aldosterone; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Dipeptides; Diuretics; Electrolytes; Enalapril; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypokalemia; Male; Middle Aged; Pyrazines; Renin | 1983 |
[Treatment of cardiac failure with diuretics. A double-blind study comparing a fixed combination of hydrochlorothiazide/amiloride and furosemide plus potassium substitution].
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Middle Aged; Potassium; Pyrazines | 1983 |
[Treatment of arterial hypertension with a combination of hydrochlorothiazide and hydrochloride amiloride].
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Sodium | 1983 |
[Report on the clinical evaluation of the antihypertensive effects of Urandil A VUFB].
Topics: Adult; Aged; Amiloride; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Isoindoles; Male; Middle Aged; Pyrazines | 1984 |
[A combination of methyldopa, hydrochlorothiazide and amiloride in the treatment of essential hypertension].
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Posture; Pulse; Pyrazines; Urea; Uric Acid | 1984 |
Timolol and a hydrochlorothiazide-amiloride combination in the treatment of essential hypertension in young and middle-aged patients: a comparative study with once-daily administration.
Topics: Adult; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Timolol | 1984 |
Hydrochlorothiazide in combination with potassium-sparing agents in the treatment of hypertension.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Random Allocation; Triamterene | 1984 |
Comparison of thiazides and amiloride in treatment of moderate hypertension.
Topics: Adult; Aged; Amiloride; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Metoprolol; Middle Aged; Potassium; Pyrazines | 1983 |
Comparison of a fixed ratio combination of hydrochlorothiazide, amiloride and timolol ('Moducren') given once versus twice daily in mild to moderate hypertension.
Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Administration Schedule; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Time Factors; Timolol | 1984 |
Efficacy and tolerance of a fixed ratio combination of hydrochlorothiazide, amiloride and timolol, taken before or after food, in the treatment of hypertension.
Topics: Adult; Aged; Amiloride; Drug Combinations; Female; Food; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Timolol | 1984 |
Effects of amiloride on plasma and total body potassium, blood pressure, and the renin-angiotensin-aldosterone system in thiazide-treated hypertensive patients.
Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Renin-Angiotensin System | 1983 |
A comparison of timolol plus hydrochlorothiazide plus amiloride and methyldopa in essential hypertension in Black Africans.
Topics: Adult; Amiloride; Antihypertensive Agents; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Kenya; Male; Methyldopa; Middle Aged; Pyrazines; Random Allocation; Timolol | 1983 |
Long term treatment with tienilic acid or thiazides: comparison of antihypertensive and metabolic effects.
Topics: Adult; Amiloride; Blood Pressure; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Liver Function Tests; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Ticrynafen; Uric Acid | 1983 |
Potassium sparing by amiloride during thiazide therapy in hypertension.
Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines | 1984 |
A general practice study of timolol/hydrochlorothiazide/amiloride ('Moducren'), a new therapy for hypertension, and the doctor's influence on management.
Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Combinations; Family Practice; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Propanolamines; Pyrazines; Timolol | 1983 |
Response of thiazide-induced hypokalemia to amiloride.
Topics: Aldosterone; Amiloride; Bicarbonates; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Potassium; Pyrazines | 1983 |
The antihypertensive and biochemical effects of hydrochlorothiazide/amiloride (Moduretic) versus chlorthalidone.
Topics: Adult; Aged; Amiloride; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Pyrazines | 1980 |
Combination of timolol maleate, hydrochlorothiazide and amiloride hydrochloride in the treatment of hypertension: A multicentre trial.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Maleates; Middle Aged; Placebos; Potassium; Propanolamines; Pyrazines; Timolol; Urate Oxidase | 1980 |
Evaluation of a fixed combination of timolol maleate, hydrochlorothiazide and amiloride hydrochloride in the treatment of hypertension: A long-term multicentre trial.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Diastole; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Potassium; Propanolamines; Pulse; Pyrazines; Systole; Time Factors; Timolol; Uric Acid | 1980 |
Timolol and hydrochlorothiazide-amiloride in primary hypertension.
Topics: Adult; Amiloride; Blood Pressure; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Renin; Timolol | 1980 |
Effect of tienilic acid and amiloride in healthy volunteers and in hypertensives with normal renal function.
Topics: Adolescent; Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Electrolytes; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Middle Aged; Pyrazines; Ticrynafen; Uric Acid | 1980 |
Multiclinic evaluation of the antihypertensive effect of a methyldopa, hydrochlorothiazine, and amiloride combination.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Pyrazines; Random Allocation; Time Factors | 1980 |
The influence of amiloride on the therapeutic and metabolic effects of carbenoxolone in patients with gastric ulcer. A double-blind controlled trial.
Topics: Adult; Amiloride; Blood Pressure; Body Weight; Carbenoxolone; Clinical Trials as Topic; Double-Blind Method; Female; Glycyrrhetinic Acid; Humans; Male; Middle Aged; Pyrazines; Random Allocation; Stomach Ulcer | 1980 |
Multiclinic comparison of amiloride, hydrochlorothiazide, and hydrochlorothiazide plus amiloride in essential hypertension. Multicenter Diuretic Cooperative Study Group.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines | 1981 |
The effect of amiloride/hydrochlorothiazide combination vs furosemide plus potassium supplementation in the treatment of oedema of cardiac origin.
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Edema, Cardiac; Female; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium Chloride; Pyrazines | 1981 |
Antihypertensive and metabolic effects of a combination of hydrochlorothiazide and amiloride.
Topics: Adult; Aged; Amiloride; Blood Proteins; Blood Urea Nitrogen; Cholesterol; Clinical Trials as Topic; Creatinine; Drug Combinations; Electrolytes; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Time Factors | 1981 |
[Moduretic in the treatment of cardiac failure].
Topics: Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Female; Follow-Up Studies; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Pyrazines | 1981 |
Amiloride--a potassium-sparing diuretic.
Topics: Amiloride; Clinical Trials as Topic; Heart Failure; Humans; Hypertension; Hypokalemia; Pyrazines | 1981 |
A double-blind, crossover study of acebutolol and hydrochlorothiazide/amiloride diuretic in Sudanese patients with essential hypertension.
Topics: Acebutolol; Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Pulse; Pyrazines; Sudan | 1982 |
Potassium conservation with amiloride/hydrochlorothiazide ("Moduret') in thiazide-induced hypokalaemia in hypertension.
Topics: Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Potassium; Pyrazines | 1982 |
Antihypertensive, saluretic and hypokalaemic effects of cyclothiazide in comparison with hydrochlorthiazide with amiloride supplement.
Topics: Adult; Amiloride; Antihypertensive Agents; Benzothiadiazines; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Middle Aged; Natriuresis; Pyrazines | 1982 |
[The effect of hydrochlorothiazide/amiloride alone or in combination with alpha-methyldopa on serum lipoproteins].
Topics: Adult; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Methyldopa; Pyrazines | 1981 |
Effects of tienilic acid used alone and in association with triamterene or amiloride on urinary excretion of electrolytes.
Topics: Amiloride; Diuresis; Drug Interactions; Electrolytes; Female; Glycolates; Humans; Male; Middle Aged; Pyrazines; Ticrynafen; Triamterene; Uric Acid | 1981 |
[Hypertension treated with hydrochlorothiazide/amilorid and timolol maleate].
Topics: Adult; Amiloride; Blood Pressure; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Propanolamines; Pyrazines; Timolol | 1980 |
Indacrinone: modification of diuretic, uricosuric, and kaliuretic actions by amiloride.
Topics: Adult; Amiloride; Calcium; Chlorides; Creatinine; Diuretics; Double-Blind Method; Drug Synergism; Electrolytes; Humans; Indans; Indenes; Male; Phosphates; Potassium; Pyrazines; Sodium; Uricosuric Agents | 1980 |
TRPA1 and TRPV1 Antagonists Do Not Inhibit Human Acidosis-Induced Pain.
Topics: Acid Sensing Ion Channel Blockers; Acidosis; Adult; Amiloride; Analgesics; Analysis of Variance; Capsaicin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Oximes; Pain; Pain Measurement; Pyrazines; Pyridines; TRPA1 Cation Channel; TRPV Cation Channels | 2017 |
412 other study(ies) available for amiloride and pyrazines
| Article | Year |
|---|---|
Effect of amiloride and some of its analogues of cation transport in isolated frog skin and thin lipid membranes.
Topics: Amiloride; Animals; Biological Transport; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Membrane Potentials; Membranes; Membranes, Artificial; Pyrazines; Skin; Sodium | 1976 |
Importance of guanidinium groups of blocking sodium channels in epithelia.
Topics: Amidines; Amiloride; Animals; Benzimidazoles; Biological Transport; Chemical Phenomena; Chemistry; Epithelium; Guanidines; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Pyrazines; Rana temporaria; Receptors, Drug; Skin; Sodium; Tetrodotoxin; Triamterene | 1976 |
The effect of external Na and amiloride on pHi recovery in mouse soleus muscle [proceedings].
Topics: Amiloride; Hydrogen-Ion Concentration; Muscles; Pyrazines; Sodium | 1977 |
Fertilization acid production in Psammechinus eggs under pH clamp conditions, and the effects of some pyrazine derivatives.
Topics: Acids; Amiloride; Animals; Female; Fertilization; Hydrogen-Ion Concentration; Kinetics; Pyrazines; Sea Urchins; Zygote | 1978 |
K+ deprivation potentiates the renal acid excretory effect of mineralocorticoid: obliteration by amiloride.
Topics: Acid-Base Equilibrium; Acids; Amiloride; Ammonia; Animals; Bicarbonates; Desoxycorticosterone; Dogs; Hydrogen-Ion Concentration; Potassium; Pyrazines | 1979 |
Interaction of amiloride and lithium on distal urinary acidification.
Topics: Amiloride; Animals; Bicarbonates; Electrolytes; Hydrogen-Ion Concentration; Lithium; Pyrazines; Rats; Urine | 1979 |
The effects of amiloride and ouabain on urinary acidification by turtle bladder.
Topics: Acid-Base Equilibrium; Amiloride; Animals; Bicarbonates; Biological Transport; Drug Interactions; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Ouabain; Pyrazines; Sodium; Turtles; Urinary Bladder; Urine | 1979 |
Synthesis, properties and biological activity of tritiated N-benzylamidino-3,5-diamino-6-chloro-pyrazine carboxamide -- a new ligand for epithelial sodium channels.
Topics: Amiloride; Animals; Anura; Chromatography, Thin Layer; Drug Stability; Electrophoresis, Paper; Epithelium; In Vitro Techniques; Ion Channels; Ligands; Pyrazines; Rana temporaria; Sodium | 1979 |
Effect of amiloride on chloride transport across amphibian epithelia.
Topics: Amiloride; Animals; Anura; Biological Transport; Biological Transport, Active; Bufo bufo; Chlorides; Epithelium; In Vitro Techniques; Pyrazines; Rana temporaria; Skin; Sodium | 1978 |
Evidence for a transcellular component to the transepithelial sodium efflux in toad skin.
Topics: Amiloride; Animals; Biological Transport, Active; Bufo marinus; Epithelium; In Vitro Techniques; Membrane Potentials; Ouabain; Oxygen Consumption; Pyrazines; Skin; Skin Physiological Phenomena; Sodium | 1978 |
On the mechanism of the amiloride-sodium entry site interaction in anuran skin epithelia.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Bufo marinus; Calcium; Epithelium; In Vitro Techniques; Pyrazines; Rana catesbeiana; Rana pipiens; Skin; Sodium | 1979 |
Effects of ouabain and amiloride on Na pathways in turtle bladders.
Topics: Adenosine Triphosphatases; Amiloride; Animals; Biological Transport, Active; Cell Membrane Permeability; In Vitro Techniques; Membrane Potentials; Microsomes; Ouabain; Pyrazines; Sodium; Time Factors; Turtles; Urinary Bladder | 1975 |
Comparison of the local effects of amiloride hydrochloride on the isotonic fluid absorption in the distal and proximal convoluted tubule.
Topics: Absorption; Amiloride; Animals; Kidney Tubules; Kidney Tubules, Distal; Kidney Tubules, Proximal; Male; Pyrazines; Rats; Specific Pathogen-Free Organisms | 1975 |
Non-specific inhibition of membrane-ATPase by amiloride: a comparative in vivo and in vitro study with ouabain.
Topics: 4-Nitrophenylphosphatase; Adenosine Triphosphatases; Amiloride; Animals; Bicarbonates; Biological Transport, Active; In Vitro Techniques; Magnesium; Membrane Potentials; Ouabain; Potassium; Pyrazines; Rabbits; Rats; Sodium; Submandibular Gland | 1976 |
P-chloromercuribenzene sulfonate blocks and reverses the effect of amiloride on sodium transport across rabbit colon in vitro.
Topics: 4-Chloromercuribenzenesulfonate; Amiloride; Animals; Biological Transport, Active; Colon; In Vitro Techniques; Phenylmercury Compounds; Pyrazines; Rats; Sodium | 1978 |
The excretion of hydrogen ion by the isolated amphibian skin: effects of antidiuretic hormone and amiloride.
Topics: Amiloride; Animals; Biological Transport, Active; Bufo bufo; Chlorides; Hydrogen-Ion Concentration; Magnesium; Pyrazines; Ranidae; Skin; Sodium; Species Specificity; Sulfates; Time Factors; Vasopressins | 1975 |
Effects of vasopressin and aldosterone on amiloride binding in toad bladder epithelial cells.
Topics: Aldosterone; Amiloride; Animals; Biological Transport, Active; Bufo marinus; Cycloheximide; Dactinomycin; Epithelial Cells; In Vitro Techniques; Pyrazines; Sodium; Triamterene; Urinary Bladder; Vasopressins | 1975 |
Effects of an acetyl-coenzyme A carboxylase inhibitor and a sodium-sparing diuretic on aldosterone-stimulated sodium transport, lipid synthesis, and phospholipid fatty acid composition in the toad urinary bladder.
Topics: Acetates; Acetyl-CoA Carboxylase; Aldosterone; Amiloride; Animals; Biological Transport, Active; Bufo marinus; Fatty Acids; Female; Leucine; Ligases; Lipids; Nafenopin; Phospholipids; Propionates; Protein Biosynthesis; Pyrazines; RNA; Sodium; Uridine; Urinary Bladder | 1975 |
The separate modes and sites of action of furosemide and amiloride.
Topics: Amiloride; Animals; Bicarbonates; Binding Sites; Biological Transport, Active; Epithelium; Furosemide; Hydrogen-Ion Concentration; Kidney Concentrating Ability; Loop of Henle; Male; Perfusion; Potassium; Pyrazines; Rats; Sodium; Submandibular Gland; Vasopressins | 1975 |
[Drug information. Therapeutic main group: diuretics. 13. Combination preparations with potassium-preserving diuretics: amiloride and hydrochlorothiazide (Moduretic)].
Topics: Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Potassium; Pyrazines | 1979 |
Amiloride as a probe for sodium entry sites in frog skin epithelium [proceedings].
Topics: Amiloride; Animals; Anura; Binding Sites; Epithelium; In Vitro Techniques; Membrane Potentials; Pyrazines; Rana temporaria; Skin; Sodium | 1977 |
Irreversible inhibition of sodium entry sites in frog skin by a photosensitive amiloride analog.
Topics: Amiloride; Animals; Anura; Biological Transport; Depression, Chemical; Pyrazines; Rana catesbeiana; Skin; Sodium; Ultraviolet Rays | 1978 |
Reduction of chloride fluxes by amiloride across the short-circuited frog skin.
Topics: Amiloride; Animals; Anura; Chlorides; Depression, Chemical; Drug Interactions; Electric Conductivity; In Vitro Techniques; Membrane Potentials; Models, Biological; Pyrazines; Rana catesbeiana; Rana pipiens; Skin; Sodium; Theophylline | 1978 |
The effects of 2,4,6-triaminopyrimidine (TAP) on sodium and potassium excretion by the rat kidney: comparison with amiloride.
Topics: Amiloride; Animals; Anura; Electric Conductivity; Gallbladder; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Male; p-Aminohippuric Acid; Potassium; Pyrazines; Pyrimidines; Rana catesbeiana; Rats; Sodium | 1978 |
Effect of amiloride on catecholamine-induced changes in ion transport in short-circuited frog skin.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Chlorides; Epinephrine; In Vitro Techniques; Isoproterenol; Pyrazines; Rana temporaria; Skin; Sodium | 1978 |
On the cross-reactivity of amiloride and 2,4,6 triaminopyrimidine (TAP) for the cellular entry and tight junctional cation permeation pathways in epithelia.
Topics: Amiloride; Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Epithelium; Gallbladder; Ion Channels; Membrane Potentials; Pyrazines; Pyrimidines; Rana catesbeiana; Skin; Sodium | 1979 |
Potassium sparing effect of amiloride in patients receiving diuretics: a quantitative study.
Topics: Adult; Amiloride; Body Weight; Diuretics; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Pyrazines; Sodium; Time Factors | 1979 |
Estimation of the density of sodium entry sites in frog skin epithelium from the uptake of [3H]benzamil.
Topics: Amiloride; Animals; Anura; Binding Sites; Binding, Competitive; Biological Transport; Depression, Chemical; Epithelium; Kinetics; Membrane Potentials; Methods; Mucous Membrane; Osmolar Concentration; Pyrazines; Rana temporaria; Skin; Skin Physiological Phenomena; Sodium | 1979 |
Uptake of [3H]benzamil at different sodium concentrations. Inferences regarding the regulation of sodium permeability.
Topics: Amiloride; Animals; Anura; Benzamides; Binding Sites; Binding, Competitive; Biological Transport; Cell Membrane Permeability; Epithelium; Kinetics; Membrane Potentials; Pyrazines; Rana temporaria; Skin; Skin Physiological Phenomena; Sodium | 1979 |
Coupled transepithelial sodium and potassium transport across isolated frog skin: effect of ouabain, amiloride and the polyene antibiotic filipin.
Topics: Amiloride; Animals; Anura; Barium; Biological Transport, Active; Cell Membrane Permeability; Epithelium; Female; Filipin; Male; Models, Biological; Ouabain; Polyenes; Potassium; Pyrazines; Rana temporaria; Skin; Sodium | 1979 |
[Use and abuse of potassium-saving diuretics].
Topics: Amiloride; Humans; Hypertension; Pyrazines; Spironolactone; Substance-Related Disorders | 1979 |
The influence of ions, ouabain, propranolol and amiloride on the transepithelial potential and resistance of rabbit cornea.
Topics: Amiloride; Animals; Chlorides; Cornea; Electric Conductivity; Epithelium; Intraocular Pressure; Membrane Potentials; Ouabain; Potassium; Propranolol; Pyrazines; Rabbits; Sodium; Time Factors | 1979 |
Inhibitory and stimulatory effects of amiloride analogues on sodium transport in frog skin.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Drug Interactions; In Vitro Techniques; Lanthanum; Oxytocin; Propranolol; Pyrazines; Ranidae; Skin; Sodium; Structure-Activity Relationship | 1979 |
Severe hyperkalaemia with Moduretic.
Topics: Aged; Amiloride; Arrhythmias, Cardiac; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Middle Aged; Pyrazines | 1979 |
Renal sodium and potassium excretion in sheep given amiloride.
Topics: Amiloride; Animals; Female; Injections, Intravenous; Potassium; Pyrazines; Sheep; Sodium | 1979 |
Urinary magnesium excretion during amiloride administration in saline-loaded rats [proceedings].
Topics: Amiloride; Animals; Magnesium; Male; Pyrazines; Rats; Sodium Chloride | 1979 |
Time-related changes in urinary aldosterone and electrolyte excretion during amiloride administration to congestive heart failure patients [proceedings].
Topics: Aldosterone; Amiloride; Electrolytes; Heart Failure; Humans; Pyrazines; Time Factors | 1979 |
Total body potassium and long-term treatment with amiloride HCL and/or hydrochlorothiazide.
Topics: Amiloride; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Potassium; Pyrazines; Time Factors | 1979 |
Effect of amiloride on the apical cell membrane cation channels of a sodium-absorbing, potassium-secreting renal epithelium.
Topics: Absorption; Amiloride; Animals; Cell Membrane; Electric Conductivity; Female; In Vitro Techniques; Ion Channels; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Membrane Potentials; Potassium; Pyrazines; Rabbits; Sodium | 1979 |
[Results of a field study with Moducrin in 12596 hypertensive patients].
Topics: Amiloride; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol | 1979 |
[The mechanism of the increase in potassium excretion produced by furosemide (author's transl)].
Topics: Amiloride; Animals; Furosemide; Glomerular Filtration Rate; Inulin; Kidney Tubules; Kidney Tubules, Collecting; Loop of Henle; Male; Potassium; Pyrazines; Rats; Sodium | 1979 |
Effect of amiloride on isolated guinea-pig atrium.
Topics: Amiloride; Animals; Calcium; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Potassium; Pyrazines; Sodium; Stimulation, Chemical; Time Factors | 1979 |
Thiazide diuretics in renal hypercalciuria.
Topics: Adult; Amiloride; Calcium; Diuretics; Humans; Hydrochlorothiazide; Parathyroid Glands; Pyrazines; Sodium Chloride Symporter Inhibitors; Urinary Bladder Calculi | 1979 |
[The combination of hydrochlorothiazide, amiloride and alpha-methyldopa in the treatment of arterial hypertension. Clinical evaluation of a multicentric study].
Topics: Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines | 1979 |
Electrical properties of amphibian urinary bladder epithelia. III. The cell membrane resistances and the effect of amiloride.
Topics: Amiloride; Amphibians; Animals; Biological Transport, Active; Cell Membrane; Epithelium; In Vitro Techniques; Mathematics; Membrane Potentials; Pyrazines; Sodium; Urinary Bladder | 1977 |
Effects of amiloride on the response of human platelets to bovine alphathrombin.
Topics: Amiloride; Animals; Cattle; Dose-Response Relationship, Drug; Humans; Membrane Potentials; Platelet Aggregation; Pyrazines; Serotonin; Thrombin | 1978 |
Amiloride-sensitive rheogenic Na+ transport in rabbit blastocyst.
Topics: Amiloride; Animals; Biological Transport; Blastocyst; Ectoderm; Electric Conductivity; Gestational Age; Membrane Potentials; Pyrazines; Rabbits; Sodium; Trophoblasts | 1977 |
[Hyperkalemia caused by hyporeninism: role of the hydrochlorothiazide-amiloride combination].
Topics: Aged; Aldosterone; Amiloride; Diabetes Complications; Female; Heart Failure; Humans; Hydrochlorothiazide; Hyperkalemia; Pyrazines; Renin | 1977 |
[Variations of the threshold of endocardial electric stimulation in pacemaker patients treated with amiloride].
Topics: Amiloride; Heart Conduction System; Humans; Pacemaker, Artificial; Potassium; Pyrazines | 1977 |
Changes in ionic conductances and in sensitivity to amiloride during the natural moulting cycle of toad skin (Bufo viridis, L.).
Topics: Amiloride; Animals; Bufonidae; Cell Membrane Permeability; Electric Conductivity; Potassium; Pyrazines; Skin; Skin Physiological Phenomena; Sodium | 1978 |
Effect of amiloride on the renal response to saline expansion in new-born dogs.
Topics: Absorption; Amiloride; Animals; Animals, Newborn; Dogs; Female; Kidney; Male; Natriuresis; Nephrons; Potassium; Pyrazines; Sodium; Sodium Chloride | 1978 |
Interaction between cell sodium and the amiloride-sensitive sodium entry step in rabbit colon.
Topics: Amiloride; Amphotericin B; Animals; Biological Transport, Active; Colon; Electric Conductivity; Female; Male; Ouabain; Pyrazines; Rabbits; Sodium | 1978 |
Effects of some pyrazinecarboxamides on sodium transport in frog skin.
Topics: Amiloride; Animals; Anura; Biological Transport; Dose-Response Relationship, Drug; In Vitro Techniques; Pyrazines; Skin; Sodium | 1978 |
Concomitant administration of timolol and hydrochlorothiazide/amiloride in hypertensive patients. Results of a titration study.
Topics: Adult; Aged; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol | 1978 |
Amiloride-induced stimulation of HCO-3 reabsorption in turtle bladder.
Topics: Amiloride; Animals; Bicarbonates; Biological Transport, Active; Chlorides; Electric Conductivity; In Vitro Techniques; Ouabain; Pyrazines; Sodium; Turtles; Urinary Bladder | 1978 |
Ion transport by rabbit colon: II. Unidirectional sodium influx and the effects of amphotericin B and amiloride.
Topics: Amiloride; Amphotericin B; Animals; Biological Transport, Active; Colon; In Vitro Techniques; Potassium; Pyrazines; Rabbits; Sodium | 1978 |
Isolation of amiloride-resistant clones from dog kidney epithelial cells.
Topics: Amiloride; Biological Transport; Cell Communication; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Epithelium; Mitochondria; Mutation; Pyrazines; Sodium | 1978 |
A comparison of methods for measurement of rectal potential difference in man: effects of rectal infusion of amiloride.
Topics: Adult; Amiloride; Depression, Chemical; Dose-Response Relationship, Drug; Humans; Intestinal Mucosa; Male; Membrane Potentials; Methods; Pyrazines; Rectum | 1978 |
Amiloride and calcium effect on the outer barrier of the frog skin.
Topics: Amiloride; Animals; Anura; Calcium; Epithelium; In Vitro Techniques; Pyrazines; Skin; Sodium; Time Factors | 1978 |
Sodium uptake across the apical border of the isolated turtle colon: confirmation of the two-barrier model.
Topics: Amiloride; Animals; Biological Transport, Active; Colon; Epithelium; In Vitro Techniques; Intestinal Mucosa; Models, Biological; Ouabain; Pyrazines; Sodium; Time Factors; Turtles | 1978 |
The effect of clonidine, triamterene, and amiloride on pharmacokinetics and cardiotoxicity of ouabain in rabbits.
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Clonidine; Electrocardiography; Heart Rate; Kinetics; Male; Myocardium; Ouabain; Pyrazines; Rabbits; Time Factors; Triamterene | 1978 |
A new ligand for epithelial sodium channels [proceedings].
Topics: Amiloride; Animals; Anura; Biological Transport; Epithelium; In Vitro Techniques; Ion Channels; Ligands; Pyrazines; Skin; Sodium | 1978 |
[Long-term treatment of hypertension with the combination of hydrochlorothiazine and amiloride. Results of a multi-center study of 277 patients].
Topics: Adult; Aged; Amiloride; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines | 1978 |
Total exchangeable potassium in response to amiloride.
Topics: Amiloride; Body Weight; Carbon Dioxide; Humans; Hypertension; Hypokalemia; Potassium; Pyrazines; Time Factors | 1978 |
[Comparison of spironolactone and amiloride combined with hydrochlorothiazide in the treatment of slight or moderate hypertension].
Topics: Amiloride; Blood Glucose; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Spironolactone; Uric Acid | 1978 |
[Spirolactones and potassium-sparing diuretics].
Topics: Amiloride; Edema; Humans; Hyperaldosteronism; Hypertension; Pyrazines; Spironolactone; Triamterene | 1978 |
Estimation of the lifespan of amiloride binding sites in the membranes of toad bladder epithelial cells.
Topics: Aldosterone; Amiloride; Animals; Binding Sites; Bufo marinus; Cycloheximide; Epithelial Cells; Epithelium; In Vitro Techniques; Pyrazines; Regression Analysis; Sodium; Urinary Bladder | 1976 |
Effects of 2-deoxy-D-glucose, amiloride, vasopressin, and ouabain on active conductance and ENa in the toad bladder.
Topics: Amiloride; Animals; Biological Transport, Active; Bufo marinus; Deoxy Sugars; Deoxyglucose; Female; Membrane Potentials; Ouabain; Pyrazines; Sodium; Urinary Bladder; Vasopressins | 1976 |
Effect of amiloride on electrical activity and electrolyte transport in human colon.
Topics: Adult; Aged; Amiloride; Biological Transport, Active; Cell Membrane Permeability; Chlorides; Colon; Colon, Sigmoid; Drug Evaluation; Humans; Intestinal Absorption; Intestinal Mucosa; Membrane Potentials; Middle Aged; Pyrazines; Rectum; Sodium; Time Factors | 1977 |
Effect of inhibitors on transepithelial efflux of Na and nonelectrolytes in frog skin.
Topics: Amiloride; Animals; Biological Transport; Dinitrophenols; Epithelium; In Vitro Techniques; Mannitol; Ouabain; Polyethylene Glycols; Pyrazines; Skin; Sodium; Sucrose | 1977 |
[Clinico-functional evaluation of a new potassium-sparing diuretic: amiloride].
Topics: Acid-Base Equilibrium; Amiloride; Diuresis; Humans; Hyperaldosteronism; Hypokalemia; Natriuresis; Potassium; Pyrazines; Water-Electrolyte Balance | 1977 |
Effects of Ag+ on frog skin: interactions with oxytocin, amiloride and ouabain.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Electric Conductivity; Ouabain; Oxytocin; Permeability; Pyrazines; Ranidae; Silver; Skin; Skin Physiological Phenomena; Sodium | 1977 |
Mode of action of amiloride in toad urinary bladder. An electrophysiological study of the drug action on sodium permeability of the mucosal border.
Topics: Amiloride; Animals; Bufonidae; Cell Membrane Permeability; Dose-Response Relationship, Drug; Electric Conductivity; In Vitro Techniques; Membrane Potentials; Pyrazines; Sodium; Urinary Bladder | 1977 |
Amiloride in the treatment of primary hyperaldosteronism and essential hypertension.
Topics: Adult; Aged; Amiloride; Angiotensin II; Electrolytes; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Pyrazines; Renin | 1977 |
[Moduretic in ambulatory treatment of hypertension].
Topics: Adult; Amiloride; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines | 1977 |
Effects of anions on amiloride-sensitive, active sodium transport across rabbit colon, in vitro. Evidence for "trans-inhibition" of the Na entry mechanism.
Topics: Amiloride; Animals; Anions; Biological Transport, Active; Colon; Female; Kinetics; Male; Pyrazines; Rabbits; Sodium; Sulfates | 1977 |
The effect of poly-L-lysine, amiloride and methyl-L-lysine on gill ion transport and permeability in the rainbow trout.
Topics: Amiloride; Animals; Biological Transport, Active; Cell Membrane Permeability; Chlorides; Gills; Kinetics; Lysine; Peptides; Polylysine; Pyrazines; Sodium; Time Factors; Trout | 1976 |
Paradoxical reversal of the suppressed potassium secretion during treatment with combinations of antikaluretic agents (spironolactone, canrenone, triamterene, amiloride); a possible site of action in Henle's loop.
Topics: Amiloride; Canrenone; Humans; Kidney Tubules; Liver Cirrhosis; Loop of Henle; Male; Middle Aged; Potassium; Pregnadienes; Pyrazines; Sodium; Spironolactone; Triamterene | 1976 |
The effect of amiloride on the transepithelial potential difference of the distal tubule of the rat kidney.
Topics: Amiloride; Animals; Epithelium; Kidney Tubules, Distal; Male; Membrane Potentials; Microelectrodes; Potassium; Pyrazines; Rats; Rats, Inbred Strains | 1976 |
Influence of vasopressin and amiloride on shunt pathways of frog skin.
Topics: Amiloride; Animals; Biological Transport, Active; Epithelial Cells; Epithelium; Pyrazines; Skin; Sodium; Vasopressins | 1976 |
Opposite effects of spironolactone and amiloride on potassium excretion in a patient with ascites due to liver cirrhosis.
Topics: Amiloride; Ascites; Drug Interactions; Female; Humans; Liver Cirrhosis; Middle Aged; Potassium; Pyrazines; Spironolactone | 1976 |
Long-term effects of an amiloride/hydrochlorothiazide combination ('Moduretic') on electrolyte balance.
Topics: Adult; Aged; Amiloride; Drug Combinations; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines | 1976 |
Inhibition by amiloride of sodium-dependent fluid reabsorption in the rat isolated caudal epididymis.
Topics: Amiloride; Animals; Body Fluids; Depression, Chemical; Epididymis; In Vitro Techniques; Male; Pyrazines; Rats; Sodium | 1976 |
Fluid secretion by the malpighian tubules of the tsetse fly Glossina morsitans: the effects of ouabain, ethacrynic acid and amiloride.
Topics: Amiloride; Animals; Biological Transport; Cloaca; Dose-Response Relationship, Drug; Ethacrynic Acid; In Vitro Techniques; Malpighian Tubules; Ouabain; Pyrazines; Secretory Rate; Sodium; Tsetse Flies | 1976 |
[Treatment of oedematous conditions in combining amilorid and hydrochlorothiazid (author's transl)].
Topics: Amiloride; Drug Therapy, Combination; Edema; Humans; Hydrochlorothiazide; Pyrazines | 1976 |
[Combination of amiloride chlorhydrate and hydrochlorothiazide in the ambulatory treatment of mild and moderate hypertension].
Topics: Adult; Ambulatory Care; Amiloride; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines | 1976 |
[Potassium-saving effects of amiloride, triamterene and spironolactone].
Topics: Amiloride; Animals; Potassium; Pyrazines; Rats; Spironolactone; Triamterene | 1976 |
Characteristics of the entry process for sodium in transporting epithelia as revealed with amiloride.
Topics: Amiloride; Animals; Binding Sites; Epithelium; In Vitro Techniques; Membrane Potentials; Mucous Membrane; Pyrazines; Rana temporaria; Skin; Sodium; Triamterene | 1976 |
[Comparative clinical investigation of furosemide and moduretic in the treatment of cardiac failure].
Topics: Aged; Amiloride; Female; Furosemide; Heart Diseases; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Pyrazines | 1975 |
Diuretic effect of combined thiazide and amiloride.
Topics: Adult; Amiloride; Diuretics; Drug Combinations; Drug Therapy, Combination; Heart Failure; Humans; Hydrochlorothiazide; Middle Aged; Pyrazines | 1975 |
Increasing the inotropic effect and toxic dose of digitalis by the administration of antikaliuretic drugs--further evidence for a cardiac effect of diuretic agents.
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Dogs; Dose-Response Relationship, Drug; Heart; Myocardial Contraction; Myocardium; Potassium; Pyrazines; Strophanthidin; Strophanthins; Triamterene | 1975 |
The effect of aldosterone on amiloride binding sites in toad bladder epithelial cells.
Topics: Aldosterone; Amiloride; Animals; Anura; Binding Sites; Epithelial Cells; Epithelium; In Vitro Techniques; Pyrazines; Urinary Bladder | 1975 |
[The connection between Moduretic and diabetes mellitus. A case report].
Topics: Aged; Amiloride; Diabetes Mellitus; Female; Humans; Hydrochlorothiazide; Pyrazines | 1975 |
Proceedings: Local effects of amiloride hydrochloride on the isotonic fluid absorption in the distal tubule of the rat kidney.
Topics: Absorption; Amiloride; Animals; Isotonic Solutions; Kidney Tubules; Kidney Tubules, Distal; Pyrazines; Rats | 1975 |
Effect of amiloride on digitalis-induced electrocardiographic changes.
Topics: Adult; Amiloride; Depression, Chemical; Digoxin; Drug Evaluation; Electrocardiography; Exercise Test; Female; Heart; Heart Rate; Humans; Male; Potassium; Pyrazines | 1975 |
[Use of amiloride in diuretic treatment (author's transl)].
Topics: Amiloride; Diuresis; Edema; Glomerular Filtration Rate; Humans; Pyrazines | 1975 |
[Amiloride (Nilurid, M.S.D.)].
Topics: Amiloride; Humans; Potassium; Pyrazines | 1975 |
[Animal experiments on the effect of triamterene and amiloride on heart and circulation and the toxicity of digoxin (author's transl)].
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Digoxin; Drug Evaluation, Preclinical; Female; Guinea Pigs; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Ouabain; Pyrazines; Triamterene | 1975 |
Molecular recognition of amiloride analogs: a molecular electrostatic potential analysis. 1. Pyrazine ring modifications.
Topics: Amiloride; Animals; Electricity; Pyrazines; Rana ridibunda; Sodium Channels; Structure-Activity Relationship | 1992 |
Identification of a processed protein related to the human chaperonins (hsp 60) protein in mammalian kidney.
Topics: Amiloride; Amino Acid Sequence; Animals; Cattle; Chaperonins; Chromatography, Affinity; Heat-Shock Proteins; Kidney; Molecular Sequence Data; Peptide Fragments; Proteins; Pyrazines | 1992 |
Inhibition of urea transport across renal tubules by pyrazinoylguanidine and analogs.
Topics: Amiloride; Animals; Biological Transport, Active; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Guanidines; Kidney Tubules; Potassium; Pyrazines; Sodium; Structure-Activity Relationship; Urea | 1992 |
Vascular effects of tetramethylpyrazine: direct interaction with smooth muscle alpha-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amiloride; Animals; Azepines; Binding, Competitive; Dogs; In Vitro Techniques; Microsomes; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Pyrazines; Radioligand Assay; Receptors, Adrenergic, alpha; Vasodilator Agents | 1991 |
Renal and antihypertensive effects of a novel eukalemic diuretic, ICI 207,828.
Topics: Amiloride; Animals; Antihypertensive Agents; Bufonidae; Cornea; Diuretics; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Furosemide; Hydrochlorothiazide; In Vitro Techniques; Indomethacin; Kidney; Male; Potassium; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Urinary Bladder | 1992 |
Evaluation of the renal site of action of a novel, eukalemic diuretic, ICI 207,828.
Topics: Amiloride; Animals; Diuretics; Furosemide; Male; Nephrons; Potassium; Pyrazines; Rats; Rats, Inbred Strains; Sodium | 1992 |
Autoregulation of apical membrane Na+ permeability of tight epithelia. Noise analysis with amiloride and CGS 4270.
Topics: Amiloride; Animals; Cell Membrane Permeability; Electricity; Epithelium; Homeostasis; Ion Channels; Physiology; Pyrazines; Quinidine; Quinine; Rana pipiens; Skin; Sodium | 1985 |
Analysis of amiloride inhibition of chorda tympani taste response of rat to NaCl.
Topics: Amiloride; Animals; Chorda Tympani Nerve; Dose-Response Relationship, Drug; Ion Channels; Kinetics; Male; Neural Pathways; Pyrazines; Rats; Sodium Chloride; Stimulation, Chemical; Taste; Taste Buds; Time Factors | 1985 |
Cortical collecting tubule potassium secretion: effect of amiloride, ouabain, and luminal sodium concentration.
Topics: Adrenal Glands; Adrenalectomy; Amiloride; Animals; Biological Transport, Active; Desoxycorticosterone; Female; Ion Channels; Kidney Tubules; Kidney Tubules, Collecting; Ouabain; Potassium; Pyrazines; Rabbits; Sodium; Stimulation, Chemical | 1985 |
Single-channel recordings from amiloride-sensitive epithelial sodium channel.
Topics: Amiloride; Animals; Cell Line; Electric Conductivity; Epithelium; Ion Channels; Kidney; Kinetics; Pyrazines; Sodium; Xenopus | 1985 |
Electrophysiologic effects of amiloride in canine Purkinje fibers: evidence for a delayed effect on repolarization.
Topics: Action Potentials; Amiloride; Animals; Calcium; Dogs; Electrophysiology; Female; Heart; In Vitro Techniques; Ion Channels; Male; Manganese; Myocardium; Nifedipine; Nisoldipine; Purkinje Fibers; Pyrazines; Sodium; Tetrodotoxin | 1985 |
Inhibition of Na+/Ca2+ exchange in pituitary plasma membrane vesicles by analogues of amiloride.
Topics: Amiloride; Animals; Calcium; Calcium-Transporting ATPases; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ion Channels; Pituitary Gland; Potassium; Pyrazines; Sodium; Thyrotropin-Releasing Hormone | 1985 |
Structure-activity relationship of amiloride analogs as blockers of epithelial Na channels: I. Pyrazine-ring modifications.
Topics: Amiloride; Animals; Epithelium; Hydrogen-Ion Concentration; Ion Channels; Kinetics; Models, Biological; Pyrazines; Rana ridibunda; Skin; Sodium; Structure-Activity Relationship; Thermodynamics | 1985 |
Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.
Topics: Amiloride; Carrier Proteins; Cell Adhesion; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Pyrazines; Receptors, Cell Surface; Receptors, Transferrin; Sodium-Hydrogen Exchangers | 1985 |
Amiloride directly inhibits growth factor receptor tyrosine kinase activity.
Topics: Adenosine Triphosphate; Amiloride; Animals; Binding, Competitive; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Histones; Humans; Kinetics; Mice; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazines; Receptor, Insulin; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Sodium | 1985 |
Na+/H+ exchanger activity in the pig kidney epithelial cell line, LLC-PK1: inhibition by amiloride and its derivatives.
Topics: Amiloride; Ammonium Chloride; Animals; Binding, Competitive; Carrier Proteins; Cell Line; Epithelium; Kidney; Kinetics; Nigericin; Pyrazines; Sodium; Sodium-Hydrogen Exchangers; Swine | 1985 |
Amiloride inhibition of proximal tubular acidification.
Topics: Absorption; Acid-Base Equilibrium; Amiloride; Animals; Bicarbonates; Carrier Proteins; Glucose; Kidney Tubules, Proximal; Male; Mathematics; Perfusion; Pyrazines; Rats; Rats, Inbred Strains; Sodium Chloride; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1985 |
Amiloride-sensitive Na+-H+ antiporter in Escherichia coli.
Topics: Amiloride; Carrier Proteins; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Pyrazines; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence | 1985 |
The amiloride sensitive Na+/H+ antiport in guinea pig pancreatic acini. Characterization and stimulation by caerulein.
Topics: Amiloride; Animals; Carrier Proteins; Ceruletide; Dose-Response Relationship, Drug; Guinea Pigs; Kinetics; Pancreas; Potassium; Pyrazines; Sodium; Sodium-Hydrogen Exchangers | 1985 |
Mg2+ efflux is accomplished by an amiloride-sensitive Na+/Mg2+ antiport.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Chloromercuribenzenesulfonate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Antiporters; Calcium; Carrier Proteins; Chickens; Erythrocytes; Ethylmaleimide; Kinetics; Lithium; Magnesium; Pyrazines; Sodium; Sodium-Hydrogen Exchangers | 1985 |
Addition of functional amiloride-sensitive components to the receptor membrane: a possible mechanism for altered taste responses during development.
Topics: Age Factors; Amiloride; Ammonium Chloride; Animals; Chlorides; Chorda Tympani Nerve; Lithium; Lithium Chloride; Pyrazines; Rats; Sodium Chloride; Taste; Taste Buds | 1985 |
Active transport of urea by mammalian kidney.
Topics: Amiloride; Animals; Biological Transport, Active; Diuresis; Dogs; Guanidines; Kidney; Mannitol; Pyrazines; Urea | 1988 |
Synthesis and biological activity of 3-amino-5-(3,5-diamino-6-chloropyrazin-2-yl)-1,2,4-oxadiazole: an amiloride prodrug.
Topics: Amiloride; Animals; Chlorides; Diuresis; Dogs; Dosage Forms; Magnetic Resonance Spectroscopy; Natriuresis; Potassium; Pyrazines; Rats; Structure-Activity Relationship | 1986 |
Effects of hydrochlorothiazide and amiloride in renal hypophosphatemic rickets.
Topics: Adolescent; Alkaline Phosphatase; Amiloride; Bone and Bones; Calcium; Child; Child, Preschool; Chronic Kidney Disease-Mineral and Bone Disorder; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney; Male; Parathyroid Hormone; Phosphates; Pyrazines; Radiography, Abdominal; Time Factors; Ultrasonography; X Chromosome | 1985 |
Regulation of amiloride-sensitive electrogenic sodium transport in the rat colon by steroid hormones.
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Biological Transport, Active; Colon; Corticosterone; Diabetes Mellitus, Experimental; Estradiol; Glucocorticoids; Intestinal Mucosa; Kinetics; Progesterone; Pyrazines; Rats; Rats, Inbred Strains; Sodium; Testosterone | 1985 |
Amiloride-sensitive salt and fluid absorption in small intestine of sodium-depleted rats.
Topics: Adrenalectomy; Amiloride; Animals; Body Water; Colon; Diet, Sodium-Restricted; Electric Conductivity; Hyperaldosteronism; Intestinal Absorption; Intestine, Small; Intestines; Male; Membrane Potentials; Pyrazines; Rats; Rats, Inbred Strains; Sodium Chloride; Spironolactone | 1985 |
Amelioration of polyuria by amiloride in patients receiving long-term lithium therapy.
Topics: Adult; Amiloride; Body Water; Electrolytes; Female; Follow-Up Studies; Humans; Kidney Concentrating Ability; Kidney Tubules, Collecting; Lithium; Male; Middle Aged; Mood Disorders; Osmolar Concentration; Polyuria; Pyrazines | 1985 |
[Combination of methyldopa and diuretics in the treatment of hypertensive disease].
Topics: Aged; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines | 1985 |
Hydrochlorothiazide-amiloride in the treatment of congenital nephrogenic diabetes insipidus.
Topics: Adult; Alkalosis; Amiloride; Body Weight; Child; Diabetes Insipidus; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypokalemia; Kidney Tubules; Male; Pyrazines; Tolmetin | 1985 |
Extreme hyperkalemia associated with amiloride.
Topics: Aged; Amiloride; Humans; Hyperkalemia; Male; Pyrazines | 1985 |
Limitation on the use of amiloride in early renal failure.
Topics: Adult; Aged; Amiloride; Calcium; Female; Humans; Kidney Failure, Chronic; Kinetics; Magnesium; Male; Middle Aged; Potassium; Pyrazines; Sodium; Spectrometry, Fluorescence; Time Factors | 1985 |
Inhibition of synaptosomal membrane Na+-Ca2+ exchange transport by amiloride and amiloride analogues.
Topics: Adenosine Triphosphate; Amiloride; Animals; Biological Transport; Calcium; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange; Membrane Potentials; Pyrazines; Rats; Sodium; Structure-Activity Relationship; Synaptosomes | 1985 |
Amiloride inhibits the PHA-evoked mouse splenic lymphocyte proliferation.
Topics: Amiloride; Animals; Hydrogen; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Phytohemagglutinins; Potassium; Pyrazines; Sodium; Thymidine | 1985 |
Inhibition by amiloride of chorda tympani responses evoked by monovalent salts.
Topics: Amiloride; Animals; Chorda Tympani Nerve; Depression, Chemical; Evoked Potentials; Lithium; Male; Pyrazines; Rats; Rats, Inbred Strains; Sodium; Taste; Taste Buds | 1985 |
Amiloride in the treatment of lithium-induced diabetes insipidus.
Topics: Amiloride; Diabetes Insipidus; Humans; Lithium; Pyrazines | 1985 |
Effect of amiloride on experimental gentamicin nephrotoxicity.
Topics: Amiloride; Animals; Diet; Drug Interactions; Gentamicins; Inulin; Kidney; Kidney Cortex; Kidney Diseases; Kidney Tubules; Magnesium; Male; Necrosis; Potassium; Pyrazines; Rats; Rats, Inbred F344; Risk | 1985 |
Amiloride inhibition of Na+-entry into corneal endothelium.
Topics: Amiloride; Animals; Cattle; Cornea; Corneal Stroma; Electric Conductivity; Electrophysiology; Endothelium; Ouabain; Pyrazines; Sodium; Time Factors | 1985 |
Inhibition of potassium-induced contracture of the isolated rat aorta by amiloride.
Topics: Amiloride; Animals; Aorta; Calcium; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Potassium; Potassium Chloride; Pyrazines; Rats; Rats, Inbred Strains; Sodium | 1985 |
Evidence for multiple forms of receptors for amiloride in transporting epithelia.
Topics: Amiloride; Animals; Biological Transport; Bufo marinus; Colon; Diuretics; Dose-Response Relationship, Drug; Epithelium; In Vitro Techniques; Mathematics; Pyrazines; Receptors, Drug; Sodium; Time Factors | 1973 |
Plasma membranes of the kidney. 3. Influence of diuretics on ATPase activity.
Topics: Absorption; Adenosine Triphosphatases; Amiloride; Animals; Cell Membrane; Diuretics; Ethacrynic Acid; Furosemide; In Vitro Techniques; Injections, Intravenous; Kidney; Kidney Concentrating Ability; Magnesium; Male; Methods; Natriuresis; Pyrazines; Rats; Rats, Inbred Strains | 1972 |
A clinical study of Co-hydroDiuril a combination of an antikaliuretic (amiloride) and hydrochlorothiazide.
Topics: Adult; Aged; Amiloride; Blood Pressure; Blood Urea Nitrogen; Body Weight; Diuretics; Drug Combinations; Drug Eruptions; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Urinary Incontinence; Vertigo | 1972 |
Diuretics and carbohydrate metabolism: the effects of furosemide and amiloride on blood glucose, plasma insulin and cations in the rat.
Topics: Adrenalectomy; Amiloride; Animals; Blood Glucose; Chemical Phenomena; Chemistry; Diabetes Mellitus; Disease Models, Animal; Diuretics; Erythrocytes; Furosemide; Glucose Tolerance Test; Hyperkalemia; Insulin; Male; Potassium; Pyrazines; Rats; Sodium; Streptozocin | 1973 |
Effect of furosemide on sodium transport in frog skin. Interaction with amiloride and ouabain.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Diuretics; Drug Interactions; Electrophysiology; Furosemide; Ouabain; Pyrazines; Rana esculenta; Skin; Sodium | 1973 |
Amiloride and the sodium channel.
Topics: Amiloride; Animals; Anura; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Diuretics; In Vitro Techniques; Mucous Membrane; Protein Binding; Pyrazines; Rana temporaria; Skin; Sodium; Triamterene; Vasopressins | 1974 |
Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and related syndromes.
Topics: Adrenocortical Hyperfunction; Amiloride; Angiotensin II; Body Water; Corticosterone; Diuretics; Extracellular Space; Humans; Hyperaldosteronism; Hypertension; Plasma Volume; Potassium; Pyrazines; Renin; Secretory Rate; Sodium; Spironolactone; Urea | 1973 |
Adaptation to the natriuretic actions of hydrochlorothiazide, frusemide and amiloride, by rats.
Topics: Adaptation, Physiological; Adrenal Glands; Adrenalectomy; Aldosterone; Amiloride; Animals; Corticosterone; Diuresis; Diuretics; Female; Furosemide; Hydrochlorothiazide; Juxtaglomerular Apparatus; Natriuresis; Potassium; Pyrazines; Rats; Renin; Sodium; Sodium Chloride; Spironolactone; Time Factors | 1972 |
Amiloride and sodium fluxes across fish gills in fresh water and in sea water.
Topics: Amiloride; Anguilla; Animals; Biological Transport; Diuretics; Fishes; Fresh Water; Gills; Potassium; Pyrazines; Seawater; Sodium; Sodium Isotopes; Stimulation, Chemical | 1972 |
Effects of amiloride and dibucaine on a model phospholipid membrane--structure-activity relationships.
Topics: Amiloride; Calcium; Chemical Phenomena; Chemistry; Cholesterol; Dibucaine; Diuretics; Eggs; Electrophoresis; Guanidines; Kinetics; Liposomes; Membranes, Artificial; Models, Chemical; Permeability; Phosphatidylcholines; Phospholipids; Pyrazinamide; Pyrazines; Radioisotopes; Sodium Isotopes; Structure-Activity Relationship; Surface Properties | 1974 |
Tolerance and side-effects of the association hydrochlorothiazide-amiloride in long-term treatment of arterial hypertension.
Topics: Adult; Aged; Amiloride; Calcium; Creatinine; Drug Combinations; Drug Tolerance; Humans; Hydrochlorothiazide; Hypercalcemia; Hypertension; Hypocalcemia; Middle Aged; Potassium; Pyrazines; Sodium; Time Factors; Urea; Uric Acid | 1974 |
Proceedings: Effect of diuretics and vagus blockade on the release of avian prolactin.
Topics: Amiloride; Animals; Ducks; Electric Stimulation; Electrophoresis, Polyacrylamide Gel; Lidocaine; Pituitary Gland; Prolactin; Pyrazines; Salt Gland; Vagus Nerve | 1974 |
[Electrophysiologic studies on the cardiac effect of amiloride].
Topics: Amiloride; Animals; Electrophysiology; Guinea Pigs; Heart; Pyrazines | 1974 |
[Letter: Potassium retaining diuretics].
Topics: Amiloride; Humans; Potassium; Pyrazines; Spironolactone; Stimulation, Chemical; Triamterene | 1974 |
Submandibular secretion in the dog after intraluminal injections of amiloride.
Topics: Amiloride; Animals; Chlorides; Diuretics; Dogs; Female; Injections; Male; Osmosis; Pilocarpine; Potassium; Pyrazines; Saliva; Salivation; Sodium; Submandibular Gland | 1974 |
Effect of amiloride on sodium transport across body surfaces of freshwater animals.
Topics: Amiloride; Ammonia; Animals; Anura; Astacoidea; Biological Transport, Active; Chlorides; Diuretics; Hydrogen-Ion Concentration; Pyrazines; Rana pipiens; Salmonidae; Sodium; Sodium Isotopes; Urine | 1973 |
Effects of amiloride on the in vitro frog gastric mucosa.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Cell Membrane Permeability; Diuretics; Gastric Juice; Gastric Mucosa; In Vitro Techniques; Membrane Potentials; Potassium; Pyrazines; Rana pipiens; Secretory Rate | 1973 |
Some aspects of the use of Moduretic in the treatment of patients with mild hypertension.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines | 1973 |
[The treatment of cardiac edemas with a new diuretic (combination of amiloride and hydrochlorothiazide)].
Topics: Adult; Aged; Amiloride; Diuretics; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Pyrazines | 1973 |
[Potassium depletion in cardiology. Action of amiloride, a potassium sparing diuretic].
Topics: Adult; Aged; Amiloride; Arrhythmias, Cardiac; Coronary Disease; Digitalis Glycosides; Diuretics; Female; Heart Diseases; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Potassium Deficiency; Pyrazines | 1973 |
[Comparison of the combination of hydrochlorothiazide and amiloride (Moduretic) and furosemide in the treatment of cardiac edema].
Topics: Aged; Amiloride; Diuretics; Drug Combinations; Female; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Pyrazines | 1973 |
Antikaluretic action of amiloride.
Topics: Amiloride; Animals; Calcium; Diuretics; Furosemide; Hydrochlorothiazide; Kidney; Potassium; Pyrazines; Rats; Spironolactone | 1973 |
Prevention of diuretic-induced electrolyte disturbances by amiloride in patients with ascites due to cirrhosis of the liver.
Topics: Acidosis; Alkalosis; Amiloride; Ascites; Diuretics; Humans; Hypokalemia; Hyponatremia; Liver Cirrhosis; Pyrazines; Water-Electrolyte Balance | 1973 |
The importance of the guanidine group in the insulin-stimulatory effect of amiloride hydrochloride.
Topics: Amiloride; Amines; Animals; Diuretics; Guanidines; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organ Culture Techniques; Pyrazines; Rats; Secretory Rate; Structure-Activity Relationship; Time Factors | 1973 |
Effect of amiloride and hydrochlorothiazide on body fluids and electrolytes in geriatric patients with congestive cardiac failure.
Topics: Aged; Amiloride; Body Fluids; Diuretics; Electrolytes; Heart Failure; Humans; Hydrochlorothiazide; Potassium; Pyrazines; Radioisotope Dilution Technique; Sodium; Water-Electrolyte Balance | 1974 |
Effect of ADH, aldosterone, ouabain, and amiloride on toad bladder epithelial cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aldosterone; Amiloride; Animals; Biological Transport, Active; Bufo marinus; Carbon Isotopes; Creatine; Diuretics; Epithelial Cells; Epithelium; Glucose; In Vitro Techniques; Ouabain; Phosphocreatine; Pyrazines; Pyruvates; Sodium; Stimulation, Chemical; Urinary Bladder; Vasopressins | 1972 |
The role of calcium ions in the interaction of amiloride with membrane receptors.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Bufo marinus; Calcium; Cell Membrane; Diuretics; Drug Interactions; In Vitro Techniques; Kinetics; Lanthanum; Membrane Potentials; Protein Binding; Pyrazines; Rana temporaria; Receptors, Drug; Skin; Sodium; Urinary Bladder | 1972 |
The effects of acetazolamide and amiloride on tissue electrolytes, with reference to the teratogenesis of carbonic anhydrase inhibition.
Topics: Acetazolamide; Acid-Base Equilibrium; Amiloride; Animals; Bicarbonates; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Diuretics; Hydrogen-Ion Concentration; Liver; Muscles; Potassium; Pyrazines; Rats; Sodium; Water-Electrolyte Balance | 1972 |
[Treatment of the edemato-ascitic syndrome in cirrhotics, role of amiloride (MK870)].
Topics: Adult; Aged; Amiloride; Ascites; Diuretics; Edema; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Pyrazines | 1972 |
[Diuretic treatment of arterial hypertension. Value of potassium sparing].
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines | 1972 |
The effect of amiloride on sodium and potassium fluxes in red cells.
Topics: Amiloride; Biological Transport, Active; Cell Membrane Permeability; Diuretics; Erythrocytes; Humans; In Vitro Techniques; Ouabain; Potassium; Potassium Isotopes; Pyrazines; Sodium; Sodium Isotopes | 1973 |
Amiloride in primary hyperaldosteronism with chronic peptic ulceration.
Topics: Aged; Amiloride; Bicarbonates; Blood Pressure; Body Water; Chlorides; Chronic Disease; Diuretics; Female; Humans; Hyperaldosteronism; Hypertension; Peptic Ulcer; Potassium; Pyrazines; Sodium; Spironolactone; Urea | 1973 |
Use of amiloride as a potassium conserving agent in severe cardiac disease.
Topics: Adult; Aged; Amiloride; Bicarbonates; Chlorides; Diuretics; Female; Furosemide; Heart Diseases; Humans; Male; Middle Aged; Potassium; Pyrazines; Sodium; Time Factors; Urea | 1973 |
Potassium-escape phenomenon in rats during continuous application of amiloride. IV. Etiology of the escape phenomenon.
Topics: Amiloride; Animals; Body Weight; Diet; Diuretics; Feces; Male; Potassium; Pyrazines; Rats | 1973 |
A comparison of moduretic and hydrochlorothiazide in the treatment of hypertension in African patients.
Topics: Adult; Aged; Amiloride; Blood Pressure; Diuretics; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium Chloride; Pyrazines; Urea; Uric Acid | 1973 |
Evaluation of amiloride combined with hydrochlorothiazide (Moduretic) in the treatment of hypertension.
Topics: Adult; Aged; Amiloride; Benzothiadiazines; Diuretics; Drug Combinations; Female; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Propranolol; Pyrazines; Urea; Uremia | 1973 |
Teratogenic effects of intrauterine injection of acetazolamide and amiloride in hamsters.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Amiloride; Animals; Cricetinae; Diuretics; Female; Forelimb; Hindlimb; Injections, Intraperitoneal; Pyrazines; Uterus | 1973 |
Effects of hydrochlorothiazide and amiloride on potassium distribution in skeletal muscle of the rat.
Topics: Amiloride; Animals; Body Weight; Chlorides; Diuretics; Extracellular Space; Hydrochlorothiazide; Male; Muscles; Potassium; Pyrazines; Rats; Sodium; Water | 1973 |
Influence of amphotericin, amiloride, ionophores, and 2,4-dinitrophenol on the secretion of the isolated cat's pancreas.
Topics: Amiloride; Amphotericin B; Animals; Anti-Bacterial Agents; Biological Transport, Active; Cats; Cell Membrane; Cell Membrane Permeability; Dinitrophenols; Female; In Vitro Techniques; Male; Mitochondria; Pancreas; Perfusion; Pyrazines; Tyrothricin; Valinomycin | 1973 |
[Renal uptake and intrarenal distribution of amiloride].
Topics: Amiloride; Animals; Autoradiography; Carbon Isotopes; Diuretics; Female; Freezing; Kidney; Mice; Pyrazines | 1973 |
New drugs--no. 9, amiloride hydrochloride.
Topics: Amiloride; Animals; Diuretics; Humans; Potassium; Pyrazines | 1973 |
Kinetics and bioavailability of two formulations of amiloride in man.
Topics: Adult; Amiloride; Biological Transport; Biopharmaceutics; Carbon Radioisotopes; Diuretics; Dose-Response Relationship, Drug; Half-Life; Humans; Kidney Tubules, Distal; Kinetics; Male; Middle Aged; Pyrazines; Sodium | 1973 |
[Treatment of chronic low serum potassium levels in potassium losing kidney by amiloride (author's transl)].
Topics: Administration, Oral; Adult; Amiloride; Chronic Disease; Diuretics; Drug Evaluation; Humans; Hypokalemia; Kidney; Kidney Diseases; Male; Potassium; Potassium Chloride; Pyrazines | 1974 |
Effect of amiloride, furosemide, and ethacrynic acid on Na transport in the rat kidney.
Topics: Amiloride; Animals; Biological Transport; Diuresis; Diuretics; Ethacrynic Acid; Furosemide; Inulin; Kidney Tubules, Proximal; Pyrazines; Radioisotopes; Rats; Sodium; Sodium Isotopes; Tritium | 1974 |
Effect of intraluminal amiloride on Na transport in the rat proximal tubule.
Topics: Amiloride; Animals; Biological Transport; Carbon Radioisotopes; Depression, Chemical; Diuretics; Kidney Tubules, Proximal; Perfusion; Pyrazines; Radioisotopes; Rats; Sodium; Sodium Isotopes; Water | 1974 |
[Effect of amiloride on electrolyte transport in the rat colon and its dependency from mineral corticoids].
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Biological Transport, Active; Colon; Dexamethasone; Diuretics; Intestinal Absorption; Male; Mineralocorticoids; Pyrazines; Rats; Sodium Chloride; Water | 1974 |
Effect of amiloride on metabolic alkalosis and hypokalaemia after cardiopulmonary bypass surgery.
Topics: Adult; Alkalosis; Amiloride; Ammonia; Carbon Dioxide; Cardiac Surgical Procedures; Chlorides; Diuretics; Extracorporeal Circulation; Female; Humans; Hydrogen-Ion Concentration; Hypokalemia; Male; Middle Aged; Postoperative Complications; Potassium; Pyrazines; Sodium; Urine | 1974 |
Ion transport in cortical collecting tubule; effect of amiloride.
Topics: Absorption; Amiloride; Animals; Biological Transport, Active; Chlorides; Diuretics; Electrophysiology; Hydrogen-Ion Concentration; Kidney Cortex; Kidney Tubules; Loop of Henle; Permeability; Potassium; Pyrazines; Rabbits; Sodium | 1974 |
[New drugs registered in Austria: Amiloride-HCl].
Topics: Amiloride; Diuresis; Diuretics; Humans; Kidney Tubules; Pyrazines | 1972 |
Inhibition of lithium transport across toad bladder by amiloride.
Topics: Amiloride; Animals; Anura; Biological Transport; Biological Transport, Active; Bufonidae; Diuretics; In Vitro Techniques; Lithium; Membrane Potentials; Mucous Membrane; Potassium; Pyrazines; Serous Membrane; Sodium; Urinary Bladder; Water | 1972 |
[The effect of amiloride on electrolyte transport in rat colon].
Topics: Adrenalectomy; Amiloride; Animals; Bicarbonates; Biological Transport; Chlorides; Colon; Diuretics; Ion Exchange; Membrane Potentials; Potassium; Pyrazines; Rats; Sodium | 1972 |
[Effects of amphotericin, amiloride, ionophores and 2-4 dinitrophenol on the secretory rate of the isolated cat pancreas].
Topics: Aerobiosis; Amiloride; Amphotericin B; Anaerobiosis; Animals; Anti-Bacterial Agents; Cats; Cell Membrane Permeability; Dinitrophenols; Diuretics; Ion Exchange; Mitochondria; Pancreas; Perfusion; Pyrazines; Secretory Rate; Tyrothricin; Valinomycin | 1972 |
Exchangeable potassium in heart disease: long-term effects of potassium supplements and amiloride.
Topics: Adult; Aged; Amiloride; Coronary Disease; Diuretics; Erythrocytes; Female; Furosemide; Heart Diseases; Heart Valve Diseases; Humans; Male; Middle Aged; Potassium; Potassium Isotopes; Pyrazines; Uric Acid | 1972 |
Effects of the chronic administration of amiloride hydrochloride (N-amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate) on electrolyte balance in the dog.
Topics: Amiloride; Animals; Bicarbonates; Calcium; Carbon Dioxide; Chlorides; Diuretics; Dogs; Feces; Female; Heart Atria; Heart Ventricles; Hematocrit; Hemoglobins; Ileum; Magnesium; Male; Muscles; Phosphorus; Potassium; Pyrazines; Sodium; Time Factors; Water-Electrolyte Balance | 1971 |
Potassium-escape-phenomenon in rats during continuous application of amiloride. II. Influence of pretreatment with diets of different potassium content and of adrenalectomy.
Topics: Adrenal Glands; Adrenalectomy; Amiloride; Animals; Diet; Diuresis; Diuretics; Kidney; Male; Muscles; Potassium; Pyrazines; Rats; Rats, Inbred Strains; Sodium | 1971 |
Potassium-escape-phenomenon in rats during continuous application of amiloride. 3. Influence of acid and alkali loading.
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Amiloride; Ammonium Chloride; Animals; Bicarbonates; Diuresis; Diuretics; Hydrogen-Ion Concentration; Male; Nephrectomy; Potassium; Pyrazines; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Urea | 1971 |
[Role of antikaliuretics and catecholamines in the prevention of cardiac necroses of metabolic origin].
Topics: Adrenal Cortex Hormones; Amiloride; Animals; Catecholamines; Digitoxin; Diuretics; Epinephrine; Heart Diseases; Kidney; Magnesium; Metabolic Diseases; Necrosis; Oils; Phenoxybenzamine; Potassium; Potassium Chloride; Propranolol; Pyrazines; Rats; Sodium; Stress, Physiological | 1971 |
[Prevention of electrolyte-steroid cardiopathy with amiloride. Light- and electron microscopic studies].
Topics: Amiloride; Animals; Diuretics; Heart; Heart Diseases; Microscopy, Electron; Myocardium; Pyrazines; Rats | 1971 |
[Effect of amiloride (MK-870 or 3-carboguanidino-2,6-diamino-5-chloropyrazine) on urinary electrolyte excretion].
Topics: Amiloride; Animals; Diuresis; Diuretics; Electrolytes; Male; Osmolar Concentration; Potassium; Pyrazines; Rats; Sodium; Water-Electrolyte Balance | 1971 |
The amiloride receptor.
Topics: Amiloride; Animals; Anura; Biological Transport; Calcium; Diuretics; In Vitro Techniques; Oxygen Consumption; Pyrazines; Receptors, Drug; Skin; Sodium; Urinary Bladder | 1971 |
Absorption, distribution and elimination of 14 C-amiloride in normal human subjects.
Topics: Amiloride; Carbon Isotopes; Diuretics; Humans; Intestinal Absorption; Pyrazines | 1971 |
The use of amiloride hydrochloride in the correction of hypokalaemic alkalosis induced by diuretics.
Topics: Alkalosis; Amiloride; Bicarbonates; Diuretics; Humans; Hypokalemia; Potassium; Pyrazines | 1971 |
Amiloride, Ca 2+ and oxygen consumption of the urinary bladders of toads.
Topics: Acetates; Amiloride; Animals; Anura; Biological Transport; Calcium Chloride; Chelating Agents; Diuretics; Drug Synergism; Ethers; Europium; In Vitro Techniques; Lanthanum; Mathematics; Oxygen Consumption; Polarography; Pyrazines; Sodium; Sodium Chloride; Urinary Bladder | 1971 |
The role of the Na+/H+ exchange system in cardiac cells in relation to the control of the internal Na+ concentration. A molecular basis for the antagonistic effect of ouabain and amiloride on the heart.
Topics: Amiloride; Animals; Biological Transport, Active; Carrier Proteins; Cells, Cultured; Chick Embryo; Drug Antagonism; Heart; Hydrogen-Ion Concentration; Kinetics; Myocardium; Ouabain; Pyrazines; Rats; Sodium; Sodium-Hydrogen Exchangers | 1984 |
Amiloride-sensitive Na+/H+ exchange in human neutrophils: mechanism of activation by chemotactic factors.
Topics: Amiloride; Ammonia; Carrier Proteins; Choline; Humans; Hydrogen-Ion Concentration; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyrazines; Sodium-Hydrogen Exchangers | 1984 |
Activation of amiloride-sensitive sodium transport in C6 glioma cells.
Topics: Amiloride; Animals; Biological Transport, Active; Bradykinin; Bucladesine; Cell Line; Colchicine; Diglycerides; Epidermal Growth Factor; Glioma; Protons; Pyrazines; Rats; Sodium; Tetradecanoylphorbol Acetate | 1984 |
Amiloride-sensitive Na+-H+ exchange in platelets and leukocytes: detection by electronic cell sizing.
Topics: Amiloride; Animals; Blood Platelets; Cell Count; Culture Media; Cytoplasm; Humans; Hydrogen-Ion Concentration; Ion Channels; Leukocytes; Lymphocytes; Macrophages; Neutrophils; Osmosis; Propionates; Pyrazines; Rats; Sodium | 1984 |
Stimulation of Na-K-ATPase in the rat collecting tubule by two diuretics: furosemide and amiloride.
Topics: Adenosine Triphosphatases; Aldosterone; Amiloride; Animals; Diuretics; Furosemide; Kidney Tubules; Kidney Tubules, Collecting; Male; Pyrazines; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical | 1984 |
Voltage-dependent block by amiloride and other monovalent cations of apical Na channels in the toad urinary bladder.
Topics: Amiloride; Animals; Binding Sites; Binding, Competitive; Bufo marinus; Cesium; Electrophysiology; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Potassium; Pyrazines; Rubidium; Sodium; Urinary Bladder | 1984 |
Characterization of potent Na+/H+ exchange inhibitors from the amiloride series in A431 cells.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Dogs; Epidermal Growth Factor; Hydrogen-Ion Concentration; Intracellular Fluid; Kinetics; Leucine; Ouabain; Potassium; Pyrazines; Rabbits; Rubidium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1984 |
Effect of arterial carbon dioxide tension on amiloride-sensitive sodium absorption in the colon.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Amiloride; Animals; Carbon Dioxide; Colon; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Ion Channels; Pyrazines; Rats; Rats, Inbred Strains; Sodium Chloride; Water-Electrolyte Balance | 1984 |
The interaction of amiloride analogues with the Na+/H+ exchanger in kidney medulla microsomes.
Topics: Amiloride; Animals; Carrier Proteins; Glucose; Hydrogen-Ion Concentration; Kidney Medulla; Microsomes; Pyrazines; Rabbits; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchangers | 1984 |
Identification of apical membranes from tight epithelia using spin-labeled amiloride and electron paramagnetic resonance spectroscopy.
Topics: Amiloride; Animals; Biological Transport; Cell Fractionation; Cell Membrane; Electron Spin Resonance Spectroscopy; Epithelium; Gills; Kidney; Pyrazines; Rana pipiens; Sarcolemma; Sodium; Spin Labels | 1984 |
Apical membrane properties and amiloride binding kinetics of the human descending colon.
Topics: Adult; Aged; Amiloride; Colon; Electric Conductivity; Humans; Intracellular Membranes; Ion Channels; Kinetics; Membrane Potentials; Middle Aged; Osmolar Concentration; Pyrazines | 1984 |
[3H]ethylpropylamiloride, a radio-labelled diuretic for the analysis of the Na+/H+ exchange system. Its use with kidney cell membranes.
Topics: Amiloride; Animals; Binding, Competitive; Carrier Proteins; Cell Membrane; Kidney; Kinetics; Microvilli; Pyrazines; Rabbits; Sodium-Hydrogen Exchangers; Structure-Activity Relationship; Tritium | 1984 |
Saturation behavior of single, amiloride-sensitive Na+ channels in planar lipid bilayers.
Topics: Amiloride; Animals; Cell Line; Electric Conductivity; Ion Channels; Kidney; Lipid Bilayers; Pyrazines; Sodium; Xenopus | 1984 |
Ion transport and metabolic effects of amiloride in canine tracheal mucosa.
Topics: Amiloride; Animals; Cell Membrane Permeability; Chlorides; Dogs; Epithelium; Ion Channels; Mucous Membrane; Pyrazines; Sodium; Trachea | 1984 |
Amiloride blockable sodium fluxes in toad bladder membrane vesicles.
Topics: Amiloride; Animals; Biological Transport; Bufo marinus; Calcimycin; Calcium Chloride; Cell Membrane; Cell-Free System; Diffusion; Dose-Response Relationship, Drug; Ion Channels; Kinetics; Pyrazines; Sodium; Urinary Bladder | 1984 |
Differential antihypertensive effect of acebutolol and hydrochlorothiazide/amiloride hydrochloride combination on elevated exercise blood pressures in hypertensive patients.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Exercise Test; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Sodium Chloride Symporter Inhibitors | 1980 |
[Determination of trimepranol, chlorthalidone, DH-ergocristine and amiloride simultaneously].
Topics: Amiloride; Chlorthalidone; Chromatography, Thin Layer; Drug Combinations; Ergolines; Metipranolol; Propanolamines; Pyrazines; Spectrophotometry | 1980 |
[Physiopathological basis for a tailored management of essential hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Locomotion; Male; Middle Aged; Potassium; Pyrazines; Renin; Sodium | 1981 |
Malignant hyperkalaemia after amiloride/hydrochlorothiazide treatment.
Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Potassium; Pyrazines | 1981 |
Seasonal changes in sodium transport and amiloride sensitivity in the isolated intestine of the earthworm, Lumbricus terrestris (L.).
Topics: Amiloride; Animals; Biological Transport, Active; Drug Resistance; Electric Conductivity; Electrophysiology; Intestinal Absorption; Intestines; Oligochaeta; Pyrazines; Seasons; Sodium | 1984 |
Amiloride inhibits protein synthesis in isolated rat hepatocytes.
Topics: Adenosine Triphosphate; Amiloride; Amino Acids; Animals; Depression, Chemical; In Vitro Techniques; Liver; Male; Protein Biosynthesis; Pyrazines; Rats; RNA; Sodium; Time Factors | 1981 |
Amiloride is a cholinergic antagonist in the rabbit pancreas.
Topics: Acetylcholine; Amiloride; Amylases; Animals; Calcium; Carbachol; In Vitro Techniques; Kinetics; Pancreas; Pancreatic Juice; Pyrazines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic | 1984 |
Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Epidermal Growth Factor; Humans; Kinetics; Mice; Mice, Inbred BALB C; Mitosis; Protein Biosynthesis; Protons; Pyrazines; RNA; Sodium; Sodium-Hydrogen Exchangers | 1984 |
[Efficacy of the association of atenolol with an amiloride-hydrochlorothiazide combination in the treatment of persistent arterial hypertension].
Topics: Adult; Aged; Amiloride; Atenolol; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Retrospective Studies | 1984 |
The effect of single-dose methyldopa and diuretic on BP and left ventricular mass.
Topics: Adult; Aged; Amiloride; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines; Stroke Volume; Time Factors | 1984 |
Multicompartment kinetic analysis of the amiloride block of Na+ fluxes in frog skin.
Topics: Amiloride; Animals; Anura; Computers; Ion Channels; Kinetics; Pyrazines; Skin; Sodium | 1980 |
Amiloride-resistant Madin-Darby canine kidney (MDCK) cells exhibit decreased cation transport.
Topics: Amiloride; Animals; Biological Transport, Active; Cations; Cell Line; Dogs; Drug Resistance; Ion Channels; Kidney; Mutation; Ouabain; Pyrazines; Pyruvates; Sodium | 1981 |
The effect of amiloride on hormonal regulation of amino acid transport in isolated and cultured adult rat hepatocytes.
Topics: Amiloride; Aminoisobutyric Acids; Animals; Biological Transport; Bucladesine; Cells, Cultured; Glucagon; Insulin; Kinetics; Liver; Male; Pyrazines; Rats | 1981 |
Chemotactic factors activate differentiable permeation pathways for sodium and calcium in rabbit neutrophils. Effect of amiloride.
Topics: Amiloride; Animals; Ascitic Fluid; Calcium; Cell Membrane Permeability; Chemotactic Factors; In Vitro Techniques; Ion Channels; Neutrophils; Pyrazines; Rabbits; Sodium | 1981 |
Inhibition by amiloride of sodium transport into rabbit kidney medulla microsomes.
Topics: Amiloride; Animals; Biological Transport, Active; Cell Fractionation; Kidney Medulla; Kinetics; Microscopy, Electron; Microsomes; Pyrazines; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions; Succinate Dehydrogenase | 1982 |
Induction of amiloride-sensitive sodium transport in the intestines by adrenal steroids.
Topics: Adrenal Cortex Hormones; Amiloride; Animals; Biological Transport; Intestinal Mucosa; Intestines; Male; Pyrazines; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase | 1981 |
Inhibition of mouse mastocytoma protein kinases by amiloride.
Topics: Amiloride; Animals; Calcium; Cyclic AMP; Mast-Cell Sarcoma; Mice; Ouabain; Protein Kinase Inhibitors; Pyrazines | 1982 |
Inhibition of amiloride-sensitive sodium conductance by indoleamines.
Topics: Amiloride; Animals; Bronchi; Colon; Epithelium; In Vitro Techniques; Intestinal Mucosa; Ion Channels; Melatonin; Papio; Pyrazines; Rats; Serotonin; Structure-Activity Relationship; Trachea | 1982 |
Na+ channels and amiloride-induced noise in the mammalian colon epithelium.
Topics: Amiloride; Animals; Colon; Electric Conductivity; Intestinal Mucosa; Ion Channels; Kinetics; Pyrazines; Rabbits; Sodium | 1982 |
The amiloride-sensitive Na+/H+ exchange system in skeletal muscle cells in culture.
Topics: Amiloride; Animals; Biological Transport; Cells, Cultured; Chick Embryo; Hydrogen-Ion Concentration; Ion Exchange; Kinetics; Muscles; Protons; Pyrazines; Sodium | 1982 |
Amiloride-sensitive sodium channels in rabbit and guinea-pig gall-bladder.
Topics: Amiloride; Animals; Electric Conductivity; Epithelium; Gallbladder; Guinea Pigs; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Potassium; Pyrazines; Rabbits; Sodium | 1982 |
Growth factor activation of an amiloride-sensitive Na+/H+ exchange system in quiescent fibroblasts: coupling to ribosomal protein S6 phosphorylation.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Cell Membrane; Cricetinae; Cricetulus; DNA Replication; Fibroblasts; Insulin; Kinetics; Lung; Phosphorylation; Pyrazines; Ribosomal Protein S6; Ribosomal Proteins; Rubidium; Sodium; Sodium-Hydrogen Exchangers | 1982 |
Insulin enhances protein phosphorylation in isolated hepatocytes by inhibiting an amiloride sensitive phosphatase.
Topics: Amiloride; Animals; Glucagon; Insulin; Liver; Male; Phosphoric Monoester Hydrolases; Phosphorylation; Proteins; Pyrazines; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1982 |
Stimulation of transepithelial sodium and chloride transport by ascorbic acid. Induction of Na+ channels is inhibited by amiloride.
Topics: Amiloride; Animals; Ascorbic Acid; Biological Transport, Active; Bufo marinus; Chlorides; Cornea; Epithelium; Ion Channels; Kinetics; Pyrazines; Sodium | 1982 |
A fluctuation analysis study of the development of amiloride-sensitive Na+ transport in the skin of larval bullfrogs (Rana catesbeiana).
Topics: Amiloride; Animals; Biological Transport, Active; Ion Channels; Kinetics; Larva; Pyrazines; Rana catesbeiana; Skin; Sodium | 1982 |
Amiloride, protein synthesis, and activation of quiescent cells.
Topics: Amiloride; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Cell Line; Cell-Free System; Cycloheximide; Interphase; Mice; Peptide Chain Elongation, Translational; Protein Biosynthesis; Pyrazines; Sodium; Sodium-Potassium-Exchanging ATPase | 1982 |
Effect of amiloride on potential difference across rectal mucosa in cystic fibrosis patients.
Topics: Adolescent; Adult; Amiloride; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans; Infant; Intestinal Mucosa; Ion Channels; Membrane Potentials; Pyrazines; Rectum; Sodium; Water-Electrolyte Balance | 1982 |
Bretylium opens mucosal amiloride-sensitive sodium channels.
Topics: Amiloride; Animals; Bretylium Compounds; Bretylium Tosylate; Ion Channels; Membrane Potentials; Mucous Membrane; Pyrazines; Rana pipiens; Skin; Sodium | 1982 |
[Effect of nucleotides, amiloride and ions on active ion transport by the frog skin. A single-membrane model].
Topics: Adenine Nucleotides; Amiloride; Animals; Biological Transport, Active; In Vitro Techniques; Ion Channels; Ions; Pyrazines; Rana ridibunda; Skin Absorption; Sodium | 1983 |
Evidence that amiloride antagonises insulin-stimulated protein phosphorylation by inhibiting protein kinase activity.
Topics: Amiloride; Animals; ATP Citrate (pro-S)-Lyase; Insulin Antagonists; Liver; Male; Molecular Weight; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Pyrazines; Rabbits; Rats; Rats, Inbred Strains | 1983 |
Biochemical characterization of the amiloride-sensitive Na+/H+ antiport in Chinese hamster lung fibroblasts.
Topics: Amiloride; Animals; Blood Platelets; Carrier Proteins; Cattle; Cell Line; Cricetinae; Cricetulus; Digitonin; Endothelium; Epithelium; Humans; Hydrogen-Ion Concentration; Kinetics; Lithium; Lung; Models, Biological; Muscle, Smooth, Vascular; Pyrazines; Sodium-Hydrogen Exchangers | 1983 |
Epidermal growth factor stimulates amiloride-sensitive 22Na+ uptake in A431 cells. Evidence for Na+/H+ exchange.
Topics: Amiloride; Calcium; Carcinoma, Squamous Cell; Carrier Proteins; Cell Line; Dose-Response Relationship, Drug; Epidermal Growth Factor; Humans; Ouabain; Pyrazines; Sodium; Sodium-Hydrogen Exchangers | 1983 |
Amiloride directly inhibits the Na,K-ATPase activity of rabbit kidney proximal tubules.
Topics: Amiloride; Animals; Dose-Response Relationship, Drug; Female; Ion Channels; Kidney Tubules, Proximal; Nystatin; Ouabain; Oxygen Consumption; Pyrazines; Rabbits; Rats; Sodium; Sodium-Potassium-Exchanging ATPase | 1983 |
Apparent inhibition of Na+/H+ exchange by amiloride and harmaline in acridine orange studies.
Topics: Acridine Orange; Alkaloids; Amiloride; Animals; Carrier Proteins; Cell Membrane; Harmaline; Hydrogen-Ion Concentration; Kidney Cortex; Kinetics; Microvilli; Potassium; Pyrazines; Rats; Sodium-Hydrogen Exchangers | 1983 |
The intracellular localization of amiloride in frog skin.
Topics: Amiloride; Animals; Cell Membrane; Cytoplasm; Epidermis; In Vitro Techniques; Ion Channels; Microscopy, Fluorescence; Pyrazines; Rana pipiens; Skin; Sodium | 1983 |
The amiloride-sensitive Na+/H+ antiport in 3T3 fibroblasts.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Fetal Blood; Fibroblasts; Hydrogen-Ion Concentration; Kinetics; Mice; Mice, Inbred BALB C; Nigericin; Pyrazines; Quaternary Ammonium Compounds; Sodium; Sodium-Hydrogen Exchangers | 1983 |
Competitive blocking of apical sodium channels in epithelia.
Topics: Amiloride; Animals; Epithelium; Ion Channels; Kinetics; Mathematics; Models, Biological; Pyrazines; Rana catesbeiana; Skin; Sodium; Triamterene | 1983 |
Amiloride-sensitive trypsinization of apical sodium channels. Analysis of hormonal regulation of sodium transport in toad bladder.
Topics: Aldosterone; Amiloride; Animals; Biological Transport; Bufo marinus; Ion Channels; Pyrazines; Pyruvates; Stimulation, Chemical; Trypsin; Urinary Bladder; Vasopressins | 1983 |
Amiloride-inhibited Na+ uptake into toad bladder microsomes is Na+-H+ exchange.
Topics: Amiloride; Animals; Biological Transport, Active; Bufo marinus; Carrier Proteins; Hydrogen-Ion Concentration; Kinetics; Microsomes; Pyrazines; Sodium; Sodium-Hydrogen Exchangers; Urinary Bladder | 1983 |
[Suppression of Na, K-ATPase in the rat kidney by the sodium channel inhibitor amiloride].
Topics: Amiloride; Animals; Ion Channels; Kidney Cortex; Pyrazines; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Triamterene | 1983 |
Mixed type inhibition of the renal Na+/H+ antiporter by Li+ and amiloride. Evidence for a modifier site.
Topics: Amiloride; Animals; Carrier Proteins; Female; Kidney; Kinetics; Lithium; Mathematics; Pyrazines; Rabbits; Sodium; Sodium-Hydrogen Exchangers | 1983 |
Chemical stimulation of Na transport through amiloride-blockable channels of frog skin epithelium.
Topics: 4-Chloromercuribenzenesulfonate; Amiloride; Animals; Binding, Competitive; Epithelium; Guanidines; In Vitro Techniques; Ion Channels; Pyrazines; Rana ridibunda; Skin; Sodium; Trinitrobenzenesulfonic Acid | 1983 |
Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Chickens; Dose-Response Relationship, Drug; Mice; Pyrazines; Sodium-Hydrogen Exchangers; Structure-Activity Relationship | 1983 |
Reconstituted amiloride-inhibited sodium transporter from rabbit kidney medulla is responsible for Na+-H+ exchange.
Topics: Amiloride; Animals; Bicarbonates; Biological Transport, Active; Calcium; Carrier Proteins; Chlorides; Kidney Medulla; Magnesium; Microsomes; Potassium; Pyrazines; Rabbits; Sodium; Sodium-Hydrogen Exchangers; Valinomycin | 1984 |
Amiloride and other blockers of electrolyte flux as inhibitors of progesterone-stimulated meiotic maturation in Xenopus oocytes.
Topics: Amiloride; Animals; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Female; Ion Channels; Meiosis; Oocytes; Pyrazines; Structure-Activity Relationship; Xenopus laevis | 1984 |
Blockade of the Na+/H+ antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Cricetinae; Cricetulus; DNA Replication; Growth Substances; Interphase; Kinetics; Lung; Pyrazines; Sodium; Sodium-Hydrogen Exchangers; Structure-Activity Relationship | 1984 |
Structure-activity relationships of amiloride and certain of its analogues in relation to the blockade of the Na+/H+ exchange system.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Chick Embryo; Kinetics; Mice; Muscles; Pyrazines; Sodium; Sodium-Hydrogen Exchangers; Structure-Activity Relationship | 1984 |
The sinusoidal domain of the plasma membrane of rat hepatocytes contains an amiloride-sensitive Na+/H+ antiport.
Topics: Amiloride; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carrier Proteins; Cell Membrane; Hydrogen-Ion Concentration; Kinetics; Liver; Pyrazines; Rats; Sodium-Hydrogen Exchangers | 1984 |
[Blocking by amiloride of hydrogen ion-activated sodium permeability of sensory neuron membranes].
Topics: Amiloride; Animals; Cell Membrane Permeability; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Neurons, Afferent; Pyrazines; Rats; Trigeminal Nerve | 1984 |
Identification of an amiloride sensitive Na+/H+ exchange system in brain synaptosomes.
Topics: Acid-Base Equilibrium; Amiloride; Animals; Brain; Culture Techniques; Ion Channels; Kinetics; Pyrazines; Rats; Sodium; Synaptosomes | 1984 |
Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line.
Topics: Amiloride; Carrier Proteins; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pyrazines; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1984 |
[Blocking of proton-activated sodium permeability of the membranes of trigeminal ganglion neurons in the rat by organic cations].
Topics: Amiloride; Aminopyridines; Animals; Calcium; Cell Membrane Permeability; Guanidine; Guanidines; Hydrogen-Ion Concentration; Magnesium; Pyrazines; Rats; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Trigeminal Ganglion; Trigeminal Nerve | 1984 |
22Na+ fluxes in thymic lymphocytes. I. Na+/Na+ and Na+/H+ exchange through an amiloride-insensitive pathway.
Topics: Amiloride; Animals; Biological Transport; Electric Conductivity; Hydrogen; Lithium; Male; Potassium; Pyrazines; Radioisotopes; Rats; Rats, Inbred Strains; Rubidium; Sodium; Sodium Radioisotopes; T-Lymphocytes; Temperature; Thymus Gland | 1984 |
22Na+ fluxes in thymic lymphocytes. II. Amiloride-sensitive Na+/H+ exchange pathway; reversibility of transport and asymmetry of the modifier site.
Topics: Amiloride; Animals; Biological Transport; Hydrogen; Hydrogen-Ion Concentration; Lithium; Male; Osmolar Concentration; Pyrazines; Rats; Rats, Inbred Strains; Sodium; Sodium Radioisotopes; T-Lymphocytes; Temperature; Thymus Gland | 1984 |
Sodium-selective micro-electrode study of apical permeability in frog skin: effects of sodium, amiloride and ouabain.
Topics: Amiloride; Animals; Biological Transport; Cell Membrane Permeability; Electrochemistry; Epithelium; In Vitro Techniques; Membrane Potentials; Microelectrodes; Ouabain; Pyrazines; Rana temporaria; Skin; Skin Physiological Phenomena; Sodium | 1984 |
Metabolic effects of high dose amiloride and spironolactone: a comparative study in normal subjects.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Dose-Response Relationship, Drug; Endocrine Glands; Humans; Male; Metabolism; Mineralocorticoids; Potassium; Pyrazines; Renin; Sodium; Spironolactone; Time Factors | 1984 |
Characteristics of an amiloride-sensitive sodium entry pathway in cultured rodent glial and neuroblastoma cells.
Topics: Amiloride; Animals; Biological Transport; Blood; Calcimycin; Cell Division; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Fenfluramine; Glioma; Kinetics; Mice; Neuroblastoma; Neurons; Pyrazines; Rats; Sodium | 1983 |
Cellular Li+ opens paracellular path in toad skin: amiloride blockable effect.
Topics: Amiloride; Animals; Bufo marinus; Calcium; Cell Membrane Permeability; Lithium; Potassium; Pyrazines; Skin; Sodium; Sucrose | 1983 |
Thiazides and amiloride in treatment of moderate hypertension.
Topics: Amiloride; Benzothiadiazines; Diuretics; Humans; Hypertension; Pyrazines; Sodium Chloride Symporter Inhibitors | 1983 |
Comparison of thiazides and amiloride in treatment of moderate hypertension.
Topics: Amiloride; Blood Glucose; Humans; Hydrochlorothiazide; Hypertension; Pyrazines | 1983 |
Hyponatraemia during treatment with chlorpropamide and Moduretic (amiloride plus hydrochlorothiazide).
Topics: Aged; Amiloride; Chlorpropamide; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hyponatremia; Male; Middle Aged; Pyrazines | 1984 |
Effects of amiloride on calcium uptake by myocytes isolated from adult rat hearts.
Topics: Amiloride; Animals; Calcium; Egtazic Acid; Myocardium; Pyrazines; Rats; Sarcolemma; Sodium; Time Factors | 1984 |
Hyponatraemia and Moduretic (amiloride plus hydrochlorothiazide)
Topics: Aged; Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines | 1984 |
Hyponatraemia associated with trimethoprim and a diuretic.
Topics: Aged; Amiloride; Body Weight; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines; Trimethoprim; Urinary Tract Infections; Urodynamics | 1984 |
Effect of amiloride on cisternal fluid [HCO3-] in acute respiratory acidosis.
Topics: Acidosis, Respiratory; Acute Disease; Amiloride; Animals; Bicarbonates; Carbon Dioxide; Dogs; Electrolytes; Injections, Intraventricular; Ion Exchange; Pyrazines | 1984 |
Benzamil binding to kidney cell membranes.
Topics: Amiloride; Animals; Binding Sites; Cell Membrane; Chickens; Fishes; Guinea Pigs; In Vitro Techniques; Kidney; Microvilli; Niacinamide; Pyrazines; Rabbits; Ranidae; Rats; Species Specificity | 1981 |
Oral potassium chloride and amiloride in hydrochlorothiazide-induced potassium loss.
Topics: Administration, Oral; Adult; Aldosterone; Amiloride; Biological Availability; Creatinine; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Kinetics; Male; Middle Aged; Potassium; Pyrazines; Sodium | 1984 |
[Photosensitivity due to combined hydrochlorothiazide and amiloride].
Topics: Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Middle Aged; Photosensitivity Disorders; Pyrazines; Ultraviolet Rays | 1984 |
Amiloride, a diuretic with in vitro antimicrobial activity.
Topics: Amiloride; Anti-Bacterial Agents; Bacteria; Microbial Sensitivity Tests; Pyrazines | 1984 |
[Combination of carbonated baths with potassium-sparing diuretics].
Topics: Adult; Amiloride; Balneology; Carbonates; Diuresis; Drug Combinations; Humans; Hydrochlorothiazide; Male; Middle Aged; Natriuresis; Potassium; Pyrazines | 1984 |
Regulation of the permeability of the medaka fish embryo chorion by exogeneous sodium and calcium ions.
Topics: Amiloride; Animals; Calcium; Chorion; Electron Probe Microanalysis; Fishes; Microscopy, Electron, Scanning; Permeability; Pyrazines; Sodium | 1984 |
Amiloride: relationship between cardiac effects and inhibition of Na+/Ca2+ exchange.
Topics: Amiloride; Animals; Calcium; Cattle; Digitalis; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Pyrazines; Sarcolemma; Sodium | 1984 |
Amiloride inhibition of triiodothyronine stimulated hepatocyte proliferation in vivo, and involvement of the intracellular Na+ content in mitotic regulation: an X-ray microanalytic study.
Topics: Amiloride; Animals; Cell Division; Cell Nucleus; Chlorides; DNA Replication; Electron Probe Microanalysis; Female; Liver; Mitosis; Potassium; Pyrazines; Rats; Rats, Inbred Strains; Sodium; Triiodothyronine | 1984 |
Magnesium- and potassium-sparing effects of amiloride. Review and recent findings.
Topics: Amiloride; Animals; Homeostasis; Humans; Kidney; Kidney Tubules, Distal; Kidney Tubules, Proximal; Kinetics; Loop of Henle; Magnesium; Potassium; Pyrazines; Rats; Reference Values; Water-Electrolyte Balance | 1984 |
Additive hypocalciuric effects of amiloride and hydrochlorothiazide in patients treated with calcitriol.
Topics: Absorption; Adolescent; Adult; Amiloride; Calcitriol; Calcium; Child; Child, Preschool; Diuretics; Drug Interactions; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypophosphatemia, Familial; Male; Pseudohypoparathyroidism; Pyrazines; Rickets; Sodium | 1984 |
Effect of pH and amiloride on the intrarenal formation of kinins.
Topics: Amiloride; Animals; Dogs; Hydrogen-Ion Concentration; Kallikreins; Kidney; Kinetics; Kinins; Male; Pyrazines; Rats; Rats, Inbred Strains; Species Specificity | 1983 |
Amiloride reduces the taste intensity of Na+ and Li+ salts and sweeteners.
Topics: Amiloride; Humans; Lithium; Neurons; Pyrazines; Salts; Sodium; Structure-Activity Relationship; Sweetening Agents; Taste; Tongue | 1983 |
Amiloride potentiation of differentiation of human promyelocytic cell line HL-60.
Topics: Amiloride; Cell Line; Dimethyl Sulfoxide; Drug Synergism; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Pyrazines; Structure-Activity Relationship | 1984 |
Inhibition of Na+/Ca2+ exchange in membrane vesicle and papillary muscle preparations from guinea pig heart by analogs of amiloride.
Topics: Amiloride; Animals; Calcium; Carrier Proteins; Cell Membrane; Guinea Pigs; Heart Ventricles; Kinetics; Myocardial Contraction; Myocardium; Pyrazines; Sarcolemma; Sodium; Sodium-Calcium Exchanger; Structure-Activity Relationship | 1984 |
Sodium flux ratio through the amiloride-sensitive entry pathway in frog skin.
Topics: Amiloride; Amphotericin B; Animals; Nystatin; Pyrazines; Rana catesbeiana; Skin; Skin Physiological Phenomena; Sodium | 1983 |
Amiloride inhibits anti-Ig induction of proliferation in a human B-lymphoma cell population.
Topics: Amiloride; Antibodies, Anti-Idiotypic; B-Lymphocytes; Biological Transport; DNA; Humans; Lymphocyte Activation; Lymphoma; Pyrazines; Rubidium; Tetradecanoylphorbol Acetate; Thymidine | 1983 |
Intracellular ion activities in frog skin in relation to external sodium and effects of amiloride and/or ouabain.
Topics: Amiloride; Animals; Chlorides; Epithelium; Membrane Potentials; Microelectrodes; Ouabain; Potassium; Pyrazines; Rana temporaria; Skin; Skin Physiological Phenomena; Sodium | 1984 |
Amiloride fluxes across erythrocyte membranes.
Topics: Amiloride; Cell Membrane Permeability; Erythrocyte Membrane; Humans; Mathematics; Pyrazines; Sodium | 1983 |
Effect of amiloride with or without hydrochlorothiazide on urinary calcium and saturation of calcium salts.
Topics: Adult; Aged; Amiloride; Calcium; Calcium Oxalate; Calcium Phosphates; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Potassium; Pyrazines | 1983 |
Sodium transport from blood to brain: inhibition by furosemide and amiloride.
Topics: Amiloride; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Furosemide; Hydrogen-Ion Concentration; Male; Pyrazines; Radioisotopes; Rats; Rats, Inbred Strains; Rubidium; Sodium | 1983 |
Effect of amiloride on electrolyte transport parameters of the main duct of the rabbit mandibular salivary gland.
Topics: Amiloride; Animals; Biological Transport; Dose-Response Relationship, Drug; Electrolytes; Epithelium; In Vitro Techniques; Mandible; Ouabain; Pyrazines; Rabbits; Salivary Glands; Sodium Chloride | 1983 |
Inhibition of Na+-dependent Ca2+ efflux from heart mitochondria by amiloride analogues.
Topics: Amiloride; Animals; Biological Transport, Active; Calcium; Cattle; In Vitro Techniques; Mitochondria, Heart; Pyrazines; Sodium | 1983 |
Demonstration of a late amiloride-sensitive event as a necessary step in initiation of DNA synthesis by thrombin.
Topics: Amiloride; Animals; Biological Transport, Active; Cell Cycle; Cell Line; DNA Replication; Embryo, Mammalian; Humans; Kinetics; Mice; Pyrazines; Rubidium; Thrombin | 1983 |
Dose-dependent reduction in renal magnesium clearance by amiloride during frusemide-induced diuresis in rats.
Topics: Amiloride; Animals; Calcium; Diuresis; Dose-Response Relationship, Drug; Furosemide; Kidney; Magnesium; Male; Potassium; Pyrazines; Rats; Rats, Inbred Strains; Sodium | 1983 |
[Current aspects of hypertension treatment. Symposium 10 years Moduretic, Budapest 9-12 June 1983].
Topics: Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Pyrazines | 1983 |
Evidence for a magnesium-sparing action by amiloride during renal clearance studies in rats.
Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Electrolytes; Glomerular Filtration Rate; Hematocrit; Kidney; Magnesium; Male; Pyrazines; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Evidence for an amiloride sensitive Na+ pathway in the amphibian diluting segment induced by K+ adaptation.
Topics: Adaptation, Physiological; Aldosterone; Amiloride; Animals; Biological Transport; Cell Membrane; Diet; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Distal; Membrane Potentials; Potassium; Pyrazines; Sodium; Urodela | 1983 |
Effects of hydrochlorothiazide combined with amiloride in atenolol-resistant hypertensive patients.
Topics: Adult; Amiloride; Atenolol; Blood Pressure; Drug Combinations; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines | 1983 |
Pressure and humoral changes induced by atenolol and hydrochlorothiazide + amiloride, alone and in free combination. A comparative between-patient study.
Topics: Adult; Amiloride; Atenolol; Blood Pressure; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Pyrazines | 1983 |
Mucosal irritant potential of a potassium-sparing diuretic and of wax-matrix potassium chloride.
Topics: Amiloride; Delayed-Action Preparations; Drug Combinations; Duodenal Ulcer; Endoscopy; Esophageal Diseases; Gastroscopy; Humans; Hydrochlorothiazide; Irritants; Male; Potassium Chloride; Pyrazines; Stomach Ulcer; Ulcer; Waxes | 1984 |
Salt taste transduction occurs through an amiloride-sensitive sodium transport pathway.
Topics: Amiloride; Animals; Biological Transport; Epithelium; Potassium Chloride; Pyrazines; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Taste; Taste Buds | 1984 |
Amiloride and diltiazem inhibition of microsomal and mitochondrial Na+ and Ca2+ transport.
Topics: Amiloride; Animals; Benzazepines; Biological Transport, Active; Calcium; Diltiazem; Intracellular Membranes; Kidney Medulla; Kinetics; Membrane Potentials; Microsomes; Mitochondria, Heart; Pyrazines; Rabbits; Sodium | 1984 |
Amiloride sensitive and insensitive sodium pathways and the cellular sodium transport pool of colonic epithelium in rats.
Topics: Amiloride; Animals; Biological Transport; Colon; Epithelial Cells; Epithelium; Intestinal Absorption; Male; Pyrazines; Rats; Sodium; Sulfates | 1984 |
Do elderly patients respond differently to treatment with Moducren?
Topics: Adult; Age Factors; Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Timolol | 1984 |
Pathways of K+ permeation across the rabbit cortical collecting tubule: effect of amiloride.
Topics: Amiloride; Animals; Biological Transport; Electric Conductivity; Female; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Mathematics; Perfusion; Permeability; Potassium; Pyrazines; Rabbits | 1984 |
Regulation of mucociliary transport. Response of mucous cells to stimulation by amiloride applied to the frog palate in vitro.
Topics: Amiloride; Animals; Biological Transport; Cilia; Electrophoresis, Polyacrylamide Gel; Epithelium; In Vitro Techniques; Membrane Potentials; Mouth Mucosa; Mucus; Palate; Pyrazines; Ranidae | 1984 |
Amiloride and glucose effects on the intracellular pH of Yoshida rat ascites hepatoma AH-130 cells grown in vivo.
Topics: Amiloride; Animals; Ascites; Cell Division; Female; Glucose; Hydrogen-Ion Concentration; Liver Neoplasms, Experimental; Pyrazines; Rats; Rats, Inbred Strains | 1984 |
High-performance liquid chromatographic analysis of amiloride in plasma and urine.
Topics: Amiloride; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Kidney; Kinetics; Male; Pyrazines; Rabbits | 1984 |
Hyponatremia induced by a combination of amiloride and hydrochlorothiazide.
Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia; Pyrazines | 1984 |
Comparison of calcium and sodium transport in early and late rat distal tubules: effect of amiloride.
Topics: Amiloride; Animals; Biological Transport, Active; Calcium; Glomerular Filtration Rate; Kidney Tubules; Kidney Tubules, Distal; Male; Organ Specificity; Perfusion; Pyrazines; Rats; Rats, Inbred Strains; Sodium | 1984 |
Effect of amiloride on conductance of toad urinary bladder.
Topics: Amiloride; Animals; Bufo marinus; Electric Conductivity; Female; Membrane Potentials; Pyrazines; Urinary Bladder | 1980 |
[Reliable lowering of blood pressure with one tablet of Moducrin daily (author's transl)].
Topics: Amiloride; Blood Pressure; Circadian Rhythm; Drug Combinations; Drug Evaluation; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol | 1980 |
Decreased sensitivity to amiloride of amphibian epithelia treated with aldosterone. Further evidence for an apical hormonal effect.
Topics: Aldosterone; Amiloride; Animals; Biological Transport, Active; Bufo marinus; Epithelium; Glucose; In Vitro Techniques; Insulin; Pyrazines; Skin; Sodium; Triamterene; Urinary Bladder | 1980 |
Inhibition by amiloride of 22Na+ transport into toad bladder microsomes.
Topics: Amiloride; Animals; Biological Transport, Active; Bufo marinus; Intracellular Membranes; Kinetics; Microsomes; Nigericin; Pyrazines; Sodium; Urinary Bladder | 1980 |
Amiloride inhibits mammalian renal kallikrein and a kallikrein-like enzyme from toad bladder and skin.
Topics: Amiloride; Animals; Bufo marinus; Depression, Chemical; Kallikreins; Kidney Tubules, Distal; Pyrazines; Rats; Skin; Urinary Bladder | 1980 |
Inhibition of urea-linked water flux and [14C]urea transport across the toad bladder by amiloride.
Topics: Amiloride; Animals; Biological Transport, Active; Bufo marinus; Inulin; Osmosis; Permeability; Pyrazines; Urea; Urinary Bladder; Vasopressins; Water | 1981 |
Renal tubular secretion and effects of the alkaline diuretics amiloride, tizolemide (Hoe 740) and 2-aminomethyl-4(1,1-dimethylethyl)-6-iodophenol hydrochloride (MK-447).
Topics: Amiloride; Animals; Butylated Hydroxytoluene; Chickens; Diuretics; Edetic Acid; Electrolytes; Iodohippuric Acid; Kidney Tubules; Pyrazines; Sulfonamides; Thiazolidines | 1981 |
On the mechanism of diminished urinary carbon dioxide tension caused by amiloride.
Topics: Acidosis, Renal Tubular; Amiloride; Animals; Carbon Dioxide; Carbonic Anhydrases; Disease Models, Animal; Dogs; Partial Pressure; Pyrazines | 1982 |
Inhibition of the serum-dependent, amiloride-sensitive sodium transport pathway in human fibroblasts by extracellular divalent cations.
Topics: Amiloride; Biological Transport; Blood; Calcium; Cell Line; Culture Media; Dose-Response Relationship, Drug; Edetic Acid; Fibroblasts; Humans; Kinetics; Magnesium; Pyrazines; Sodium | 1982 |
Amiloride stimulation of sodium transport in the presence of calcium and a divalent cation chelator.
Topics: Amiloride; Animals; Biological Transport; Bufo marinus; Calcium; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Electrophysiology; Epithelium; Pyrazines; Sodium; Urinary Bladder | 1982 |
Effect of cancer cachexia and amiloride treatment on the intracellular sodium content in tissue cells.
Topics: Amiloride; Animals; Cachexia; Chlorine; Duodenum; Liver; Liver Neoplasms, Experimental; Male; Mice; Phosphorus; Potassium; Pyrazines; Sodium | 1983 |
In vitro block of murine L 1210 leukemia cell growth by amiloride, an inhibitor of passive Na+ influx.
Topics: Amiloride; Animals; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Leukemia L1210; Male; Mice; Pyrazines; Sodium | 1983 |
[Therapy of hypertension with timolol, hydrochlorothiazide and amiloride].
Topics: Amiloride; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol | 1983 |
Effects of amiloride on tumor growth and intracellular element content of tumor cells in vivo.
Topics: Adenocarcinoma; Amiloride; Animals; Body Weight; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Liver Neoplasms, Experimental; Male; Mice; Pyrazines; Sodium | 1983 |
The transmural potential of the newt ureter: evidence for amiloride-sensitive active sodium transport.
Topics: Amiloride; Animals; Biological Transport, Active; Epithelium; In Vitro Techniques; Male; Membrane Potentials; Ouabain; Pyrazines; Sodium; Triturus; Ureter | 1983 |
[Use of antipotassiuretic diuretic amiloride in patients with chronic cardiac failure].
Topics: Amiloride; Chronic Disease; Diuresis; Heart Failure; Humans; Potassium; Potassium Deficiency; Pyrazines | 1983 |
Indomethacin- and Moduretic--induced hyperkalemia.
Topics: Aged; Amiloride; Diabetes Complications; Diabetes Mellitus; Drug Combinations; Drug Interactions; Female; Heart Failure; Humans; Hydrochlorothiazide; Hyperkalemia; Indomethacin; Pyrazines | 1983 |
Antihypertensive and metabolic effects of hydrochlorothiazide, amiloride-hydrochlorothiazide, and timolol.
Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Potassium; Propanolamines; Pyrazines; Timolol | 1983 |
A novel effect of amiloride on H+-dependent Na+ transport.
Topics: Amiloride; Animals; Biological Transport, Active; Cell Membrane; Hydrogen-Ion Concentration; Ileum; Intestinal Mucosa; Kinetics; Liposomes; Microvilli; Pyrazines; Rabbits; Sodium | 1983 |
Inhibition of Na+ influx and DNA synthesis in human fibroblasts and neuroblastoma-glioma hybrid cells by amiloride analogs.
Topics: Amiloride; Animals; Cell Line; DNA Replication; Fibroblasts; Glioma; Humans; Hybrid Cells; Neuroblastoma; Pyrazines; Sodium | 1983 |
Effect of amiloride on sodium and water reabsorption in the rabbit gall-bladder.
Topics: Absorption; Amiloride; Animals; Biological Transport; Calcium; Depression, Chemical; Dose-Response Relationship, Drug; Female; Gallbladder; In Vitro Techniques; Membrane Potentials; Pyrazines; Rabbits; Sodium; Time Factors; Water | 1983 |
Inhibition of Na+-Ca2+ exchange in rat brain by amiloride.
Topics: Adenosine Triphosphate; Amiloride; Animals; Biological Transport, Active; Brain; Calcium; In Vitro Techniques; Male; Microsomes; Pyrazines; Rats; Sodium | 1983 |
Amiloride inhibits murine erythroleukemia cell differentiation: evidence for a Ca2+ requirement for commitment.
Topics: Amiloride; Animals; Calcium; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Dimethyl Sulfoxide; Erythropoiesis; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Pyrazines; Sodium; Water | 1980 |
Effects of chemical group specific reagents on sodium entry and the amiloride binding site in frog skin: evidence for separate sites.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Binding Sites; Biological Transport, Active; In Vitro Techniques; Membrane Potentials; Methylene Blue; Pyrazines; Rana catesbeiana; Skin; Skin Physiological Phenomena; Sodium; Sulfhydryl Compounds; Trinitrobenzenesulfonic Acid | 1980 |
Sodium fluxes in human fibroblasts: effect of serum, Ca+2, and amiloride.
Topics: Amiloride; Blood; Calcium; Cells, Cultured; Epidermal Growth Factor; Fibroblasts; Humans; Male; Penis; Pyrazines; Sodium | 1981 |
Inferences on the nature of the apical sodium entry site in frog skin epithelium.
Topics: Amiloride; Animals; Benzimidazoles; Biological Transport; Epithelium; In Vitro Techniques; Oxadiazoles; Pyrazines; Rana catesbeiana; Skin; Sodium; Structure-Activity Relationship | 1981 |
Interaction of cadmium, calcium, and amiloride in the kinetics of active sodium transport through frog skin.
Topics: Amiloride; Animals; Biological Transport, Active; Cadmium; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Female; Kinetics; Male; Pyrazines; Rana catesbeiana; Regression Analysis; Skin; Sodium | 1981 |
Effect of ouabain, amiloride, and antidiuretic hormone on the sodium-transport pool in isolated epithelia from frog skin (Rana temporaria).
Topics: Amiloride; Animals; Biological Transport, Active; Epithelium; Kinetics; Mathematics; Ouabain; Pyrazines; Rana temporaria; Skin; Sodium; Vasopressins | 1982 |
Effect of amiloride, ouabain and Ba++ on the nonsteady-state Na - K pump flux and short-circuit current in isolated frog skin epithelia.
Topics: Amiloride; Animals; Barium; Biological Transport, Active; Epithelium; Kinetics; Ouabain; Potassium; Pyrazines; Rana temporaria; Skin; Sodium | 1982 |
Spironolactone and amiloride in hypertensive patients with and without aldosterone excess.
Topics: Adult; Amiloride; Blood Pressure; Body Weight; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Renin; Spironolactone; Urea | 1980 |
Effects of amiloride on oral glucose loading, serum potassium, renin, and aldosterone in diet-controlled diabetes.
Topics: Aldosterone; Amiloride; Blood Glucose; Blood Pressure; Diabetes Mellitus; Diet, Diabetic; Glucose Tolerance Test; Humans; Hyperkalemia; Insulin; Posture; Potassium; Pyrazines; Renin; Triamterene | 1980 |
Effects of amiloride on insulin release, serum glucose and insulin, and glucose tolerance of mice.
Topics: Amiloride; Animals; Blood Glucose; Female; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Pyrazines; Secretory Rate; Time Factors | 1980 |
[Antihypertensive effects of timolol and of the combination timolol, amiloride and hydrochlorothiazide].
Topics: Adult; Amiloride; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propanolamines; Pyrazines; Renin; Sodium; Timolol | 1981 |
A comparison between the natriuretic response to potassium in lithium- and amiloride-treated rats.
Topics: Amiloride; Animals; Body Weight; Dose-Response Relationship, Drug; Drinking; Lithium; Male; Natriuresis; Potassium; Pyrazines; Rats; Rats, Inbred Strains; Renin; Sodium; Time Factors | 1981 |
Amiloride in primary hyperaldosteronism.
Topics: Adult; Aged; Amiloride; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium; Prospective Studies; Pyrazines | 1982 |
Relative potency of amiloride and spironolactone in healthy man.
Topics: Adult; Amiloride; Dose-Response Relationship, Drug; Humans; Male; Potassium; Pyrazines; Sodium; Spironolactone | 1982 |
Kinetics of amiloride action in the hen coprodaeum in vitro.
Topics: Amiloride; Animals; Chickens; Cloaca; Electric Conductivity; Female; In Vitro Techniques; Kinetics; Pyrazines; Sodium | 1982 |
Sodium transport inhibition by amiloride reduces basolateral membrane potassium conductance in tight epithelia.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Epithelium; Membrane Potentials; Potassium; Pyrazines; Sodium; Urinary Bladder | 1982 |
Amiloride in Bartter's syndrome.
Topics: Adult; Amiloride; Female; Humans; Hypokalemia; Inappropriate ADH Syndrome; Magnesium; Male; Pyrazines | 1982 |
A stage-specific inhibitory effect of benzamil on Xenopus oocyte maturation located at the cell surface.
Topics: Amiloride; Animals; Biological Transport; Cell Membrane; Female; Oocytes; Ovum; Progesterone; Pyrazines; Sodium; Xenopus laevis | 1982 |
A comparative study of Moducren and Moduretic and their effect on plasma potassium in essential hypertension.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Body Weight; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propanolamines; Pyrazines; Random Allocation; Timolol | 1982 |
Solubilization and reconstitution of an amiloride-inhibited sodium transporter from rabbit kidney medulla.
Topics: Amiloride; Biological Transport, Active; Kidney Medulla; Liposomes; Microsomes; Nigericin; Pyrazines; Sodium; Solubility | 1982 |
[Severe hyperkalemia during treatment with Moduretic].
Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Pyrazines | 1982 |
[Photodermatitis during treatment with Moduretic].
Topics: Adult; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Photosensitivity Disorders; Pyrazines | 1982 |
Functional importance of sodium and potassium in the guinea pig cochlea studied with amiloride and tetraethylammonium.
Topics: Action Potentials; Amiloride; Animals; Cell Membrane Permeability; Cochlea; Cochlear Microphonic Potentials; Electrophysiology; Endolymph; Guinea Pigs; Perilymph; Potassium; Pyrazines; Sodium; Tetraethylammonium; Tetraethylammonium Compounds | 1982 |
Effect of Cl-, Na+, and amiloride on the electrical properties of dog tracheal epithelium, in vitro.
Topics: Amiloride; Animals; Chlorides; Dogs; Electrophysiology; Epithelium; In Vitro Techniques; Membrane Potentials; Pyrazines; Sodium; Trachea | 1982 |
The effect of a combination of timolol, hydrochlorothiazide and amiloride on 24 hour blood pressure control using ambulatory intra-arterial monitoring.
Topics: Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Drug Combinations; Humans; Hydrochlorothiazide; Male; Middle Aged; Monitoring, Physiologic; Propanolamines; Pyrazines; Timolol | 1982 |
Amiloride blocks cell-free protein synthesis at levels attained inside cultured rat hepatocytes.
Topics: Amiloride; Animals; Cell-Free System; Cells, Cultured; DNA; In Vitro Techniques; Kinetics; Liver; Male; Mitogens; Protein Biosynthesis; Pyrazines; Rabbits; Rats; Reticulocytes; Sodium | 1982 |
[Fluorimetric determination of amiloride in human plasma using thin-layer chromatography].
Topics: Amiloride; Chromatography, Thin Layer; Fluorometry; Humans; Pyrazines; Time Factors | 1982 |
Membrane potential and sodium flux in neuroblastoma X glioma hybrid cells: effects of amiloride and serum.
Topics: Amiloride; Animals; Blood; Cell Line; Dose-Response Relationship, Drug; Glioma; Hybrid Cells; Membrane Potentials; Mice; Neuroblastoma; Pyrazines; Rats; Sodium; Thymidine | 1982 |
Irreversible inhibition of sodium transport by the toad urinary bladder following photolysis of amiloride analogs.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; In Vitro Techniques; Pyrazines; Sodium; Ultraviolet Rays; Urinary Bladder | 1981 |
The effects of sodium and amiloride on the motility of the caudal epididymal spermatozoa of the rat.
Topics: Amiloride; Animals; Dose-Response Relationship, Drug; Epididymis; Male; Pyrazines; Rats; Sodium; Sperm Motility | 1981 |
[Diuretic therapy in the aged. A clinical comparison between two diuretic compounds].
Topics: Aged; Amiloride; Diuretics; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Pyrazines; Quinazolines; Sulfonamides | 1981 |
The effects of amiloride and triamterene on urinary magnesium excretion in conscious saline-loaded rats.
Topics: Amiloride; Animals; Electrolytes; Furosemide; Magnesium; Male; Pyrazines; Rats; Triamterene | 1981 |
Amiloride-induced changes in digoxin dynamics and kinetics: abolition of digoxin-induced inotropism with amiloride.
Topics: Adult; Amiloride; Digoxin; Female; Hemodynamics; Humans; Kidney; Kinetics; Male; Myocardial Contraction; Pyrazines | 1981 |
Extraction of a [3H]benzamil binding component from kidney cell membranes.
Topics: Amiloride; Animals; Cell Membrane; Digitonin; Kidney Cortex; Molecular Weight; Pyrazines; Rats; Receptors, Drug | 1981 |
Effects of amiloride on contractions and the release of tritium from rat vas deferens preloaded with [3H]-noradrenaline.
Topics: Amiloride; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Potassium Chloride; Pyrazines; Rats; Tyrosine; Vas Deferens | 1981 |
New drug evaluations amiloride (Midamor, Merck, Sharp and Dohme).
Topics: Amiloride; Half-Life; Humans; Hypertension; Kinetics; Potassium; Pyrazines | 1981 |
Effects of amiloride and SITS on branchial ion fluxes in rainbow trout, Salmo gairdneri.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Biological Transport; Chlorides; Epithelium; Gills; Hydrogen-Ion Concentration; Pyrazines; Stilbenes; Trout | 1981 |
Amiloride sensitivity of the transepithelial electrical potential and of sodium and potassium transport in rat distal colon in vivo.
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Biological Transport; Colon; Epithelium; Male; Membrane Potentials; Potassium; Pyrazines; Rats; Sodium | 1981 |
Prevention of calcium nephrolithiasis with low-dose thiazide, amiloride and allopurinol.
Topics: Adult; Allopurinol; Amiloride; Calcium; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Pyrazines; Uric Acid | 1981 |
Renal tubule transport and electrolyte effects of amiloride in the chicken.
Topics: Amiloride; Animals; Biological Transport, Active; Chickens; Electrolytes; Female; Kidney Tubules; p-Aminohippuric Acid; Pyrazines | 1981 |
[Moducrin--a new combined preparation in the treatment of hypertension (author's transl)].
Topics: Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Prospective Studies; Pyrazines; Timolol | 1981 |
Amiloride-sensitive ammonium and sodium ion transport in the blue crab.
Topics: Acclimatization; Amiloride; Ammonia; Animals; Biological Transport, Active; Brachyura; Gills; Kinetics; Oxygen Consumption; Pyrazines; Sodium | 1981 |
Amiloride inhibition of the Na+-H+ exchanger in renal microvillus membrane vesicles.
Topics: Amiloride; Animals; Bicarbonates; Biological Transport, Active; Glucose; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Microvilli; Pyrazines; Rabbits; Sodium | 1981 |
Effects of spironolactone and amiloride on corticosteroid-induced changes in colonic function.
Topics: Adrenal Cortex Hormones; Amiloride; Animals; Biological Transport, Active; Colon; In Vitro Techniques; Jejunum; Male; Perfusion; Pyrazines; Rats; Sodium; Spironolactone; Water | 1981 |
Amiloride treatment in patients with potassium-losing nephropathy.
Topics: Aged; Amiloride; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Potassium; Pyrazines | 1981 |
Kinetic analysis of the amiloride-sodium entry site interaction in rabbit colon.
Topics: Amiloride; Animals; Binding Sites; Chemical Phenomena; Chemistry; Colon; Epithelium; Female; In Vitro Techniques; Kinetics; Male; Ouabain; Pyrazines; Rabbits; Sodium | 1981 |
Mechanism of potassium secretion in chronic renal failure studied by means of amiloride.
Topics: Amiloride; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Kidney Tubules, Distal; Nephrons; Potassium; Pyrazines; Sodium | 1981 |
[Hyponatremia associated with diuretic therapy in an elderly patient].
Topics: Aged; Amiloride; Female; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines | 1981 |
[Treatment of arterial hypertension: comparative study of atenolol + chlorthalidone vs. timolol maleate-hydrochlorthiazide-amiloride association].
Topics: Adult; Aged; Amiloride; Atenolol; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol | 1981 |
Voltage-dependent distal acidification defect induced by amiloride.
Topics: Acidosis; Amiloride; Ammonium Chloride; Animals; Electrochemistry; Potassium; Pyrazines; Rats; Sodium; Turtles; Urinary Bladder | 1980 |
Amiloride handling in renal failure.
Topics: Adult; Aged; Amiloride; Feces; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Pyrazines | 1980 |
[Value of combining amiloride with furosemide chlorthalidone in diuretic treatment].
Topics: Amiloride; Chlorthalidone; Diuresis; Drug Combinations; Furosemide; Humans; Pyrazines | 1980 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Diuretics; Female; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Potassium; Potassium Chloride; Pyrazines; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone | 1980 |
Pathophysiology of chronic renal tubular acidosis induced by administration of amiloride.
Topics: Acidosis, Renal Tubular; Adrenalectomy; Amiloride; Animals; Cell Membrane Permeability; Chronic Disease; Diet, Sodium-Restricted; Dogs; Female; Membrane Potentials; Potassium; Pyrazines; Sodium | 1980 |
Plasma potassium levels in hypertensive patients receiving fixed-combination diuretic therapy.
Topics: Adult; Aged; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Potassium; Pyrazines | 1980 |
A fixed combination of hydrochlorothiazide and amiloride for the treatment of essential hypertension.
Topics: Adolescent; Adult; Aged; Amiloride; Blood Chemical Analysis; Blood Pressure; Body Weight; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Hydrochlorothiazide; Hyperglycemia; Hypertension; Male; Middle Aged; Pyrazines; Uric Acid | 1980 |
[Comparative evaluation of the anti-hypertensive effect of moduretic and thiazides].
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Sodium Chloride Symporter Inhibitors | 1980 |
Moduretic-induced metabolic acidosis and hyperkalaemia.
Topics: Acidosis; Aged; Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Pyrazines | 1980 |
[Light-induced dermatoses during moduretic therapy].
Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Photosensitivity Disorders; Pyrazines | 1980 |
Attenuation of the lithium-induced diabetes-insipidus-like syndrome by amiloride in rats.
Topics: Amiloride; Animals; Diabetes Insipidus; Lithium; Male; Polyuria; Potassium; Pyrazines; Rats; Sodium; Syndrome; Thirst; Water | 1981 |
Saliva from patients with cystic fibrosis inhibits amiloride-sensitive sodium transport.
Topics: Amiloride; Animals; Colon; Cystic Fibrosis; Electrophysiology; In Vitro Techniques; Intestinal Absorption; Male; Pyrazines; Rats; Saliva; Sodium | 1980 |
[Inhibition of sodium transport in the colon by the diuretic amiloride (author's transl)].
Topics: Amiloride; Animals; Colon; Epithelium; In Vitro Techniques; Pyrazines; Rabbits; Sodium | 1980 |
Amiloride-induced hyponatremia.
Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines | 1980 |
Urea transport in toad skin (Bufo marinus)
Topics: Amiloride; Animals; Arginine Vasopressin; Biological Transport; Bufo marinus; Guanidines; Hydrogen-Ion Concentration; Kinetics; Ouabain; Phloretin; Pyrazines; Skin; Sodium Chloride; Urea; Urinary Bladder | 1993 |
Photolabile amiloride derivatives as cation site probes of the Na,K-ATPase.
Topics: Affinity Labels; Amiloride; Animals; Binding Sites; Cations; Dogs; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kidney; Photochemistry; Pyrazines; Sodium-Potassium-Exchanging ATPase | 1996 |
Block by amiloride derivatives of odor-evoked discharge in lobster olfactory receptor neurons through action on a presumptive TRP channel.
Topics: Amiloride; Animals; Inhibitory Concentration 50; Nephropidae; Odorants; Olfactory Receptor Neurons; Pyrazines; Signal Transduction; Structure-Activity Relationship; Transient Receptor Potential Channels | 2007 |
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3).
Topics: Acid Sensing Ion Channels; Acidosis; Amiloride; Amines; Animals; Chemistry, Pharmaceutical; Drug Design; Electrophysiology; Inhibitory Concentration 50; Male; Models, Chemical; Nerve Tissue Proteins; Pain; Pyrazines; Rats; Rats, Sprague-Dawley; Sodium Channels | 2009 |
TRPV1 controls acid- and heat-induced calcitonin gene-related peptide release and sensitization by bradykinin in the isolated mouse trachea.
Topics: Amiloride; Animals; Boron Compounds; Bradykinin; Calcitonin Gene-Related Peptide; Calcium; Extracellular Space; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Protons; Pyrazines; Pyridines; Ruthenium Red; Sensory System Agents; Sodium Channel Blockers; Trachea; TRPV Cation Channels | 2009 |
ENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration.
Topics: Administration, Inhalation; alpha 1-Antitrypsin; Amiloride; Animals; Aprotinin; Body Water; Cystic Fibrosis; Dose-Response Relationship, Drug; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Extravascular Lung Water; Fluid Shifts; Guanidines; Lung; Magnetic Resonance Imaging; Male; Mucociliary Clearance; Protease Inhibitors; Pyrazines; Rats; Rats, Inbred BN; Respiratory Mucosa; Saline Solution, Hypertonic; Sodium Channel Blockers; Time Factors | 2010 |
Calcium entry via TRPV1 but not ASICs induces neuropeptide release from sensory neurons.
Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acids; Amiloride; Animals; Calcitonin Gene-Related Peptide; Calcium; Calcium Channel Blockers; Cell Count; Cells, Cultured; GABA Antagonists; Ganglia, Spinal; Hydrogen-Ion Concentration; Phosphopyruvate Hydratase; Picrotoxin; Pyrazines; Pyridines; Rats; Sensory Receptor Cells; Substance P; TRPV Cation Channels | 2014 |
NVP-QBE170: an inhaled blocker of the epithelial sodium channel with a reduced potential to induce hyperkalaemia.
Topics: Administration, Inhalation; Amiloride; Animals; Epithelial Cells; Epithelial Sodium Channel Blockers; Guanidines; Guinea Pigs; Hyperkalemia; In Vitro Techniques; Mucociliary Clearance; Phenyl Ethers; Piperidines; Pyrazines; Rats; Respiratory Mucosa; Sheep | 2015 |