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amiloride and phenylamil

amiloride has been researched along with phenylamil in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199014 (15.73)18.7374
1990's30 (33.71)18.2507
2000's17 (19.10)29.6817
2010's24 (26.97)24.3611
2020's4 (4.49)2.80

Authors

AuthorsStudies
Astakhova, N; Boucher, RC; Geiss, WB; Hirsh, AJ; Johnson, MR; Molino, BF; Sargent, BJ; Smith, RT; Swenson, BD; Usyatinsky, A; Wyle, MJ; Zamurs, A; Zhang, J1
Bianchi, G; Ferrandi, M; Ferrari, P; Hanozet, GM; Parenti, P1
Hannam, V; O'Brodovich, H; Rafii, B1
Lazdunski, M; Van Renterghem, C1
Armstrong, J; Bourke, JR; Cragoe, EJ; Huxham, GJ; Manley, SW; Matainaho, T1
Abel, KC; Bourke, JR; Brown, L; Cragoe, EJ; Manley, SW1
Atsumi, T; Cragoe, EJ; Imae, Y; Sugiyama, S1
Cragoe, EJ; Erickson, RP; Schiffman, SS; Suggs, MS1
Barbry, P; Champe, M; Champigny, G; Chassande, O; Frelin, C; Lingueglia, E; Maes, P; Munemitsu, S; Tartar, A; Ullrich, A1
Cragoe, EJ; Simchowitz, L1
Cragoe, EJ; Garvin, JL; Mandel, LJ; Simon, SA2
Barbry, P; Cragoe, EJ; Frelin, C; Lazdunski, M; Vigne, P1
Barbry, P; Chassande, O; Cragoe, EJ; Ellory, C; Frelin, C; Lazdunski, M; Vigne, P1
Barbry, P; Champigny, G; Frelin, C; Lazdunski, M; Marsault, R; Vigne, P1
Cragoe, EJ; Oyarzabal, H; Potter, GD; Sellin, JH1
Barbry, P; Chassande, O; Duval, D; Frelin, C; Lazdunski, M; Rousseau, B1
Barbry, P; Champigny, G; Gerard, C; Lazdunski, M; Mauchamp, J; Verrier, B1
Cragoe, EJ; Oyarzabal, H; Sellin, JH1
Asher, C; Cragoe, EJ; Garty, H; Moran, A1
Barbry, P; Chassande, O; Frelin, C; Lazdunski, M; Vigne, P1
Benos, DJ; Bridges, RJ; Cragoe, EJ; Frizzell, RA1
Cragoe, EJ; Ehrenfeld, J; Harvey, BJ1
Bennington, JB; Cragoe, EJ; Knauf, PA; Lannigan, DA1
Dubinsky, WP; Sellin, JH1
Guggino, WB; Li, XJ; Snyder, SH; Xu, RH1
Bose, R; Guia, A; Leblanc, N1
Frelin, C; van Renterghem, C1
Baldwin, ML; Brasitus, TA; Cragoe, EJ; Dudeja, PK; Harig, JM; Ramaswamy, K1
Baker, M; Barbry, P; Chassande, O; Lazdunski, M; Novotny, WF1
Cragoe, EJ; Dubinsky, WP; Hall, A; Sellin, JH1
Asher, C; Barbry, P; Clauss, W; Cragoe, E; Garty, H; Goldstein, O1
Armstrong, JW; Bourke, JR; Cragoe, EJ; Huxham, GJ; Manley, SW; Yap, AS1
Betz, AL; Ennis, SR; Ren, XD1
Bose, D; Bose, R; Chau, T; Guia, A1
Homma, M; Imae, Y; Kawagishi, I; Kudo, S; Magariyama, Y; Muramoto, K; Sugiyama, S1
Homma, M; Imae, Y; Imagawa, M; Kawagishi, I; McCarter, L1
Atsumi, T; Homma, M; Kawagishi, I; Kojima, S; Kudo, S; Muramoto, K1
Blank, U; Clauss, W; Hofmann, T; Lindemann, H; Münker, G; Rückes, C; Weber, W1
Boucher, RC; Hofmann, T; Knowles, MR; Lindemann, H; Rückes, C; Stutts, MJ; Weber, WM; Ziersch, A1
Asai, Y; Atsumi, T; Homma, M; Kawagishi, I; Kojima, S1
Abdulnour-Nakhoul, S; Bor, S; Imeryuz, N; Orlando, RC1
Jaques, S; Kim, YK; McCarter, LL1
Martens, H; Schultheiss, G1
Bury, NR; Wood, CM1
Estrela, RC; Ponte, CG; Suarez-Kurtz, G1
Homma, M; Sato, K1
Alrefai, WA; Dudeja, PK; Gill, RK; Joshi, V; Ramaswamy, K; Tyagi, S1
Grosell, M; Wood, CM1
Galvez, F; Goss, GG; Hawkings, GS; Reid, SD1
Kita-Tsukamoto, K; Kogure, K; Nishino, T; Wada, M; Yao, K1
Abraham, WM; Boucher, RC; Hirsh, AJ; Hopkins, S; Paradiso, AM; Sabater, JR; Smith, RT; Zamurs, A1
Burke, J; Handy, RD1
Brown, S; Dunbar, M; Hughes, C; Klinck, J; Nichols, J; Playle, RC; Winter, A1
Diecke, FP; Fischbarg, J1
Chifflet, S; Grasso, S; Hernández, JA1
Gilmour, KM; Patel, M; Rogers, JT; Wood, CM1
Goss, GG; Parks, SK; Tresguerres, M1
Grosell, M; Nadella, SR; Wood, CM1
Davies, BS; Kim, WK; Parhami, F; Park, KW; Tontonoz, P; Waki, H; Young, SG1
Araki, M; Inui, T; Kubota, T; Miyamoto, M; Mori, Y; Nimura, Y; Takenaka, H; Watanabe, M1
Choi, SP; Park, KM; Park, KW; Tontonoz, P; Waki, H1
Chan, MC; Hata, A; Hickman, T; Hill, NS; Kang, H; Lagna, G; Mecker, SV; Nguyen, PH; Weisman, AS1
Auer, S; Ibañez-Tallon, I; Santos-Torres, J; Ślimak, MA1
Del Duca, O; Donini, A; Galperin, V; Nasirian, A1
Brix, KV; Grosell, M1
Ashe, KM; Kan, HM; Laurencin, CT; Lo, KW; Ulery, BD1
Kan, HM; Laurencin, CT; Lo, KW1
Kim, JG; Kwon, JH; Park, HC; Son, KM; Yang, HC; Zhu, T1
Brauner, CJ; Wood, CM; Zimmer, AM1
Defoirdt, T; Yang, Q1
Nadella, SR; Ng, A; Patel, D; Wood, CM1
Aghaloo, T; Bezouglaia, O; Cui, ZK; Fan, J; Fartash, A; Guo, M; Im, CS; Lee, JY; Lee, M; Nguyen, J; Wu, BM1
Fliegel, L; Goss, GG; Guffey, SC1
Aghaloo, TL; Bezouglaia, O; Cui, ZK; Fan, J; Fartash, A; Guo, M; Im, CS; Kim, S; Lee, M; Patel, N; Wang, CY; Wu, BM1
Aractingi, S; Desposito, D; Farman, N; Jaisser, F; Maubec, E; Nassar, D; Nguyen, VT; Waeckel, L1
Gonzales, EB; Snell, HD1
Kim, WK; Park, KW; Regassa, A1
Aghaloo, TL; Cui, ZK; Fan, J; Guo, M; Im, CS; Kim, S; Lee, M; Pi-Anfruns, J; Wu, BM1
Hong, C; Kang, MK; Kim, RH; Lee, C; Park, NH; Phung, S; Shin, KH; Song, M; Stevenson, RG; Yi, JK1
Leyva-Jimenez, H; Moncada, K; Park, KW; Price, TR; Tontonoz, P; Walzem, RL1
El-Fiqi, A; Kim, HW; Lee, JH; Mandakhbayar, N1
Aghaloo, TL; Cui, ZK; Fan, J; Guo, M; Im, DCS; Kim, S; Lee, M; Pi-Anfruns, J; Wu, BM1
Baker, MAB; Clark, J; Ishida, T; Ito, R; Matzke, NJ; Sowa, Y1
Bagheri, F; Fink, T; Jahed, V; Lambertsen Larsen, K; Vasheghani-Farahani, E; Zarrabi, A1
Hu, J; Liu, Y; Sun, H1
Liu, Y; Miszuk, JM; Pan, Y; Sun, H; Yao, Q1
Fong, H; Hong, Z; Hu, J; Liang, Z; Miszuk, J; Sanyour, H; Sun, H1
Atyabi, F; Damoogh, S; Dinarvand, R; Farokhi, M; Gholami, M; Motasadizadeh, H; Mottaghitalab, F; Tavakoli, M1

Other Studies

89 other study(ies) available for amiloride and phenylamil

ArticleYear
Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis.
    Journal of medicinal chemistry, 2006, Jul-13, Volume: 49, Issue:14

    Topics: Animals; Bronchi; Bronchitis, Chronic; Combinatorial Chemistry Techniques; Cystic Fibrosis; Dogs; Epithelial Sodium Channels; Guanidines; Models, Molecular; Pyrazines; Respiratory Mucosa; Sodium Channel Blockers; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tissue Culture Techniques

2006
Effect of amiloride analogues on sodium transport in renal brush border membrane vesicles from Milan hypertensive rats.
    Biochemical and biophysical research communications, 1992, Feb-28, Volume: 183, Issue:1

    Topics: Amiloride; Animals; Biological Transport, Active; Hypertension; Kidney; Membrane Potentials; Microvilli; Rats; Rats, Mutant Strains; Sodium

1992
Sodium channel but neither Na(+)-H+ nor Na-glucose symport inhibitors slow neonatal lung water clearance.
    American journal of respiratory cell and molecular biology, 1991, Volume: 5, Issue:4

    Topics: Amiloride; Animals; Animals, Newborn; Body Water; Carrier Proteins; Electricity; Guinea Pigs; Lung; Monosaccharide Transport Proteins; Phlorhizin; Sodium Channels; Sodium-Hydrogen Exchangers

1991
A new non-voltage-dependent, epithelial-like Na+ channel in vascular smooth muscle cells.
    Pflugers Archiv : European journal of physiology, 1991, Volume: 419, Issue:3-4

    Topics: Amiloride; Animals; Aorta; Cell Line; Epithelium; Kinetics; Muscle, Smooth, Vascular; Portal Vein; Sodium Channels

1991
Bidirectional ion transport in thyroid: secretion of anions by monolayer cultures that absorb sodium.
    The American journal of physiology, 1992, Volume: 262, Issue:1 Pt 1

    Topics: Absorption; Amiloride; Animals; Anions; Bicarbonates; Biological Transport; Bumetanide; Cells, Cultured; Chlorides; Cytological Techniques; Dinoprostone; Drug Resistance; Electrophysiology; Epithelial Cells; Epithelium; Ions; Sodium; Thyroid Gland

1992
Amiloride analogues induce responses in isolated rat cardiovascular tissues by inhibition of Na+/Ca2+ exchange.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:2

    Topics: Amiloride; Animals; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Heart Rate; In Vitro Techniques; Myocardial Contraction; Rats; Sodium; Vasodilation

1991
Specific inhibition of the Na(+)-driven flagellar motors of alkalophilic Bacillus strains by the amiloride analog phenamil.
    Journal of bacteriology, 1990, Volume: 172, Issue:3

    Topics: Amiloride; Aminoisobutyric Acids; Bacillus; Cell Membrane; Cell Movement; Drug Resistance, Microbial; Flagella; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Sodium; Sodium Channels

1990
Inhibition of taste responses to Na+ salts by epithelial Na+ channel blockers in gerbil.
    Physiology & behavior, 1990, Volume: 47, Issue:3

    Topics: Amiloride; Animals; Electrophysiology; Epithelium; Female; Gerbillinae; Sodium; Sodium Channels; Taste

1990
Human kidney amiloride-binding protein: cDNA structure and functional expression.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:19

    Topics: Amiloride; Amine Oxidase (Copper-Containing); Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cell Line; Cell Membrane; Cloning, Molecular; DNA; Gene Library; Humans; Kinetics; Molecular Sequence Data; Oligonucleotide Probes; Peptide Mapping; Recombinant Proteins; RNA, Messenger; Sequence Homology, Nucleic Acid; Swine; Transfection

1990
Polyvalent cations inhibit human neutrophil chemotaxis by interfering with the polymerization of actin.
    The Journal of biological chemistry, 1990, Aug-15, Volume: 265, Issue:23

    Topics: Actins; Amiloride; Calcium; Cations; Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Kinetics; Macromolecular Substances; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nickel

1990
Phenamil: an irreversible inhibitor of sodium channels in the toad urinary bladder.
    The Journal of membrane biology, 1985, Volume: 87, Issue:1

    Topics: Amiloride; Animals; Binding, Competitive; Bufo marinus; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Drug Interactions; Drug Synergism; Ion Channels; Kinetics; Mucous Membrane; Sodium; Urinary Bladder

1985
[3H]phenamil, a radiolabelled diuretic for the analysis of the amiloride-sensitive Na+ channels in kidney membranes.
    Biochemical and biophysical research communications, 1986, Feb-26, Volume: 135, Issue:1

    Topics: Amiloride; Animals; Binding Sites; Dose-Response Relationship, Drug; Epithelium; In Vitro Techniques; Ion Channels; Kidney; Sodium; Swine; Tritium

1986
Binding of 3H-phenamil, an irreversible amiloride analog, to toad urinary bladder: effects of aldosterone and vasopressin.
    The Journal of membrane biology, 1986, Volume: 90, Issue:2

    Topics: Aldosterone; Amiloride; Animals; Bufo marinus; In Vitro Techniques; Ion Channels; Kinetics; Urinary Bladder; Vasopressins

1986
Purification and subunit structure of the [3H]phenamil receptor associated with the renal apical Na+ channel.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:14

    Topics: Amiloride; Animals; Binding Sites; Cell Membrane; Chromatography, Affinity; Chromatography, Ion Exchange; Epithelium; Ion Channels; Kidney Tubules; Kidney Tubules, Distal; Molecular Weight; Receptors, Drug; Sodium Channels; Swine

1987
A new type of amiloride-sensitive cationic channel in endothelial cells of brain microvessels.
    The Journal of biological chemistry, 1989, May-05, Volume: 264, Issue:13

    Topics: Amiloride; Animals; Binding Sites; Blood-Brain Barrier; Cattle; Electric Conductivity; Endothelium, Vascular; In Vitro Techniques; Ion Channels; Potassium; Sodium

1989
Phenamil inhibits electrogenic sodium absorption in rabbit ileum.
    Gastroenterology, 1989, Volume: 96, Issue:4

    Topics: Amiloride; Animals; Chlorides; Ileum; In Vitro Techniques; Intestinal Absorption; Male; Ouabain; Rabbits; Sodium; Sodium Channels; Theophylline

1989
Biochemical identification of two types of phenamil binding sites associated with amiloride-sensitive Na+ channels.
    Biochemistry, 1989, May-02, Volume: 28, Issue:9

    Topics: Amiloride; Animals; Cell Membrane; Kidney; Kinetics; Mathematics; Receptors, Drug; Sodium Channels; Swine

1989
Identification and properties of a novel type of Na+-permeable amiloride-sensitive channel in thyroid cells.
    European journal of biochemistry, 1989, Aug-15, Volume: 183, Issue:3

    Topics: Amiloride; Animals; Cell Membrane; Cells, Cultured; Kinetics; Membrane Potentials; Sodium; Sodium Channels; Swine; Thyroid Gland

1989
Electrogenic sodium absorption in rabbit cecum in vitro.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Bicarbonates; Biological Transport; Cecum; Chlorides; Cyclic GMP; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Epinephrine; Furosemide; Intestinal Absorption; Male; Potassium; Rabbits; Sodium; Sulfhydryl Reagents; Water-Electrolyte Balance

1988
Conductive sodium pathway with low affinity to amiloride in LLC-PK1 cells and other epithelia.
    The Journal of biological chemistry, 1988, Dec-25, Volume: 263, Issue:36

    Topics: Amiloride; Animals; Cell Line; Cell Membrane; Epithelium; Erythrocyte Membrane; Female; Humans; Kidney Cortex; Kinetics; Male; Membrane Potentials; Microvilli; Rabbits; Rana ridibunda; Rats; Rats, Inbred Strains; Sodium; Sodium Channels; Valinomycin

1988
The structure of the amiloride sensitive apical Na+ channel from pig kidney.
    Kidney international. Supplement, 1988, Volume: 26

    Topics: Amiloride; Animals; Kidney; Sodium Channels; Swine

1988
Inhibition of colonic Na+ transport by amiloride analogues.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Amiloride; Animals; Biological Transport; Colon; Dexamethasone; Electric Conductivity; Electrophysiology; Epithelium; Female; Kinetics; Rats; Rats, Inbred Strains; Sodium

1989
Evidence for a Na+/H+ exchanger at the basolateral membranes of the isolated frog skin epithelium: effect of amiloride analogues.
    Pflugers Archiv : European journal of physiology, 1987, Volume: 409, Issue:1-2

    Topics: Amiloride; Animals; Biological Transport; Carrier Proteins; Epithelium; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Ouabain; Protons; Rana esculenta; Skin; Sodium; Sodium-Hydrogen Exchangers

1987
Phenamil, an amiloride analogue, inhibits differentiation of Friend murine erythroleukemic cells.
    The American journal of physiology, 1988, Volume: 254, Issue:1 Pt 1

    Topics: Amiloride; Animals; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Mice; Osmolar Concentration; Ouabain; Rubidium; Sodium

1988
Apical nonspecific cation conductances in rabbit cecum.
    The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 1

    Topics: Amiloride; Animals; Barium; Calcium; Cations, Divalent; Cecum; Cell Membrane; Colon; Dose-Response Relationship, Drug; Electric Conductivity; Ion Channels; Magnesium; Microelectrodes; Rabbits; Sodium; Sodium Channels; Solutions

1994
Alternatively spliced forms of the alpha subunit of the epithelial sodium channel: distinct sites for amiloride binding and channel pore.
    Molecular pharmacology, 1995, Volume: 47, Issue:6

    Topics: Alternative Splicing; Amiloride; Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Cell Line; Cloning, Molecular; DNA, Complementary; Epithelium; Molecular Sequence Data; Oocytes; Polymerase Chain Reaction; Protein Binding; Rats; Ribonucleases; Sodium Channels; Xenopus

1995
Effects of phenamil on potassium and calcium channels of guinea pig ventricular myocytes.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2

    Topics: Action Potentials; Amiloride; Animals; Calcium Channels; Guinea Pigs; Heart; Potassium Channels; Sodium Channel Blockers

1995
3,4 dichlorobenzamil-sensitive, monovalent cation channel induced by palytoxin in cultured aortic myocytes.
    British journal of pharmacology, 1993, Volume: 109, Issue:3

    Topics: Acrylamides; Amiloride; Animals; Aorta, Thoracic; Calcium; Cells, Cultured; Cnidarian Venoms; Electrophysiology; In Vitro Techniques; Ion Channels; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Wistar; Sodium; Sodium Channels; Sodium Radioisotopes

1993
Mechanisms of Na+ transport in human distal colonic apical membrane vesicles.
    Biochimica et biophysica acta, 1994, Jul-13, Volume: 1193, Issue:1

    Topics: Amiloride; Biological Transport; Colon; Dose-Response Relationship, Drug; Humans; Intestinal Mucosa; Kinetics; Osmolar Concentration; Sodium; Sodium Channels; Sodium Radioisotopes; Sodium-Hydrogen Exchangers

1994
Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues.
    The Journal of biological chemistry, 1994, Apr-01, Volume: 269, Issue:13

    Topics: Amiloride; Amine Oxidase (Copper-Containing); Amino Acid Sequence; Animals; Antibodies, Monoclonal; Carrier Proteins; Colon; DNA, Complementary; Female; Humans; Kidney; Kinetics; Molecular Sequence Data; Molecular Weight; Placenta; Pregnancy; Sequence Homology, Amino Acid; Swine; Transfection

1994
Characterization of an apical sodium conductance in rabbit cecum.
    The American journal of physiology, 1993, Volume: 264, Issue:1 Pt 1

    Topics: Amiloride; Animals; Cecum; Cell Membrane; Chlorides; Colon; Electric Conductivity; Hydrogen-Ion Concentration; Potassium; Rabbits; Sodium; Sodium Channels

1993
An epithelial high-affinity amiloride-binding site, different from the Na+ channel.
    The Journal of biological chemistry, 1993, Apr-15, Volume: 268, Issue:11

    Topics: Aldosterone; Amiloride; Animals; Binding Sites; Binding, Competitive; Bufo marinus; Cell Membrane; Chickens; Colon; Epithelium; Intestine, Large; Kinetics; Sodium; Sodium Channels; Sodium, Dietary; Urinary Bladder

1993
Activation of sodium transport mediates regulation of thyroid follicle volume in response to hypotonic media.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Amiloride; Animals; Cells, Cultured; Culture Media; Epithelium; Hypotonic Solutions; Kinetics; Membrane Potentials; Sodium; Sodium Channels; Swine; Thyroid Gland; Thyrotropin; Time Factors

1993
Mechanisms of sodium transport at the blood-brain barrier studied with in situ perfusion of rat brain.
    Journal of neurochemistry, 1996, Volume: 66, Issue:2

    Topics: Amiloride; Animals; Biological Transport; Blood-Brain Barrier; Brain; Bumetanide; Carrier Proteins; Cerebrovascular Circulation; Frontal Lobe; Hydrochlorothiazide; Kinetics; Perfusion; Plasma Volume; Rats; Rats, Inbred Strains; Sodium; Sodium Channels; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters

1996
Mechanism of cardiac inotropy by phenamil, and epithelial sodium channel blocker.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1

    Topics: Amiloride; Animals; Carrier Proteins; Dogs; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Myocardial Contraction; Rats; Sarcoplasmic Reticulum; Sodium Channel Blockers; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase

1996
Rotational fluctuation of the sodium-driven flagellar motor of Vibrio alginolyticus induced by binding of inhibitors.
    Journal of molecular biology, 1996, Jun-21, Volume: 259, Issue:4

    Topics: Amiloride; Cell Division; Computer Simulation; Flagella; Microscopy; Models, Biological; Molecular Structure; Movement; Protein Binding; Sodium; Sodium Channel Blockers; Sodium Channels; Vibrio

1996
The sodium-driven polar flagellar motor of marine Vibrio as the mechanosensor that regulates lateral flagellar expression.
    Molecular microbiology, 1996, Volume: 20, Issue:4

    Topics: Amiloride; Bacterial Proteins; Dose-Response Relationship, Drug; Flagella; Flagellin; Gene Expression Regulation, Bacterial; Membrane Proteins; Sodium Channels; Vibrio parahaemolyticus; Viscosity

1996
Vibrio alginolyticus mutants resistant to phenamil, a specific inhibitor of the sodium-driven flagellar motor.
    Journal of molecular biology, 1997, Jan-24, Volume: 265, Issue:3

    Topics: Amiloride; Drug Resistance, Microbial; Flagella; Mutation; Sodium; Vibrio

1997
Cystic fibrosis and non-cystic-fibrosis human nasal epithelium show analogous Na+ absorption and reversible block by phenamil.
    Pflugers Archiv : European journal of physiology, 1997, Volume: 434, Issue:1

    Topics: Amiloride; Cells, Cultured; Cystic Fibrosis; Dose-Response Relationship, Drug; Epithelium; Humans; Nasal Mucosa; Sodium

1997
Effects of topically delivered benzamil and amiloride on nasal potential difference in cystic fibrosis.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:6 Pt 1

    Topics: Administration, Intranasal; Adolescent; Adult; Aerosols; Amiloride; Cells, Cultured; Cystic Fibrosis; Epithelium; Female; Humans; In Vitro Techniques; Male; Membrane Potentials; Nasal Mucosa; Sodium Channel Blockers; Sodium Channels

1998
Na+-driven flagellar motor resistant to phenamil, an amiloride analog, caused by mutations in putative channel components.
    Journal of molecular biology, 1999, Jan-29, Volume: 285, Issue:4

    Topics: Amiloride; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; DNA Primers; Drug Resistance, Microbial; Flagella; Genes, Bacterial; Models, Molecular; Molecular Motor Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Sodium; Sodium Channels; Vibrio

1999
Mechanisms of basolateral Na+ transport in rabbit esophageal epithelial cells.
    The American journal of physiology, 1999, Volume: 276, Issue:2

    Topics: Amiloride; Ammonia; Animals; Bicarbonates; Biological Transport; Bumetanide; Chlorides; Epithelial Cells; Esophagus; Homeostasis; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Isotonic Solutions; Rabbits; Sodium

1999
Mutations conferring resistance to phenamil and amiloride, inhibitors of sodium-driven motility of Vibrio parahaemolyticus.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, May-11, Volume: 96, Issue:10

    Topics: Amiloride; Amino Acid Sequence; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cell Movement; Conserved Sequence; Membrane Proteins; Molecular Sequence Data; Mutation; Phenotype; Sodium; Vibrio parahaemolyticus

1999
Ca-sensitive Na transport in sheep omasum.
    The American journal of physiology, 1999, Volume: 276, Issue:6

    Topics: Aldosterone; Amiloride; Animals; Biological Transport; Calcium; Electric Conductivity; Feedback; Female; Magnesium; Male; Mannitol; Microelectrodes; Omasum; Serous Membrane; Sheep; Sodium; Theophylline

1999
Mechanism of branchial apical silver uptake by rainbow trout is via the proton-coupled Na(+) channel.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Amiloride; Animals; Anti-Bacterial Agents; Binding, Competitive; Biological Transport; Cations; Cell Membrane; Enzyme Inhibitors; Gills; Kinetics; Macrolides; Oncorhynchus mykiss; Protons; Silver Nitrate; Sodium Channel Blockers; Sodium Channels; Time Factors

1999
Modulation of the Ca(2+) release channel of sarcoplasmic reticulum by amiloride analogs.
    European journal of pharmacology, 2000, Mar-10, Volume: 391, Issue:1-2

    Topics: Amiloride; Animals; Caffeine; Calcium; Calcium Channels; Cetomacrogol; Diuretics; Electrophysiology; In Vitro Techniques; Isometric Contraction; Magnesium; Membranes; Muscle Fibers, Skeletal; Phosphodiesterase Inhibitors; Rabbits; Ruthenium Red; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sodium Channels; Solutions

2000
Multimeric structure of PomA, a component of the Na+-driven polar flagellar motor of vibrio alginolyticus.
    The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26

    Topics: Amiloride; Bacterial Proteins; Cell Membrane; Cell Movement; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Flagella; Mutation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sodium; Sodium Channels; Sodium Chloride; Vibrio

2000
Evidence for a Na+-H+ exchange across human colonic basolateral plasma membranes purified from organ donor colons.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:12

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Biological Transport; Bumetanide; Carbonic Anhydrase Inhibitors; Cell Membrane; Colon; Humans; Hydrogen; In Vitro Techniques; Ion Exchange; Sodium; Sodium-Potassium-Exchanging ATPase; Tissue Donors

2000
Copper uptake across rainbow trout gills: mechanisms of apical entry.
    The Journal of experimental biology, 2002, Volume: 205, Issue:Pt 8

    Topics: Amiloride; Animals; Anti-Bacterial Agents; Biological Transport; Calcium; Copper; Copper Radioisotopes; Gills; Kinetics; Macrolides; Oncorhynchus mykiss; Potassium; Proton Pump Inhibitors; Sodium; Sodium Channel Blockers

2002
Localization and characterization of phenamil-sensitive Na+ influx in isolated rainbow trout gill epithelial cells.
    The Journal of experimental biology, 2003, Volume: 206, Issue:Pt 3

    Topics: Amiloride; Animals; Anti-Bacterial Agents; Biological Transport; Bumetanide; Epithelial Cells; Female; Gills; Guanidines; Hydrogen-Ion Concentration; Macrolides; Male; Mitochondria; Models, Biological; Oncorhynchus mykiss; Ouabain; Peanut Agglutinin; Sodium; Sodium Radioisotopes; Sulfones

2003
Flagellar motors of marine bacteria Halomonas are driven by both protons and sodium ions.
    Canadian journal of microbiology, 2004, Volume: 50, Issue:5

    Topics: Adaptation, Biological; Amiloride; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Flagella; Halomonas; Microscopy, Electron; Movement; Proton Pumps; Seawater; Sodium-Potassium-Exchanging ATPase; Uncoupling Agents; Water Microbiology

2004
Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:3

    Topics: Absorption; Amiloride; Animals; Bronchi; Cystic Fibrosis; Electrophysiology; Epithelial Cells; Epithelial Sodium Channels; Epithelium; Female; Humans; In Vitro Techniques; Lung Diseases; Mannitol; Microscopy, Confocal; Mucus; Muscle Contraction; Sheep; Sodium; Sodium Channel Blockers; Sodium Channels; Viscosity

2004
Sodium-sensitive and -insensitive copper accumulation by isolated intestinal cells of rainbow trout Oncorhynchus mykiss.
    The Journal of experimental biology, 2005, Volume: 208, Issue:Pt 2

    Topics: Amiloride; Analysis of Variance; Animals; Cells, Cultured; Chlorides; Copper; Hydrogen-Ion Concentration; Intestinal Mucosa; Oncorhynchus mykiss; Sodium; Sodium Channel Blockers; Sodium Channels

2005
Influence of water chemistry and natural organic matter on active and passive uptake of inorganic mercury by gills of rainbow trout (Oncorhynchus mykiss).
    Aquatic toxicology (Amsterdam, Netherlands), 2005, Mar-25, Volume: 72, Issue:1-2

    Topics: Amiloride; Animals; Biological Transport; Biological Transport, Active; Cysteine; Dose-Response Relationship, Drug; Edetic Acid; Ethylenediamines; Fresh Water; Gills; Ions; Lanthanum; Mercury; Models, Biological; Nitrilotriacetic Acid; Oncorhynchus mykiss; Ontario; Spectrophotometry, Atomic; Verapamil

2005
A mathematical model of electrolyte and fluid transport across corneal endothelium.
    The Journal of membrane biology, 2005, Volume: 203, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Biological Transport, Active; Chloride Channels; Computer Simulation; Electrolytes; Endothelium, Corneal; Ion Channels; Kinetics; Models, Biological; Osmosis; Ouabain; Permeability; Proton-Translocating ATPases; Sodium-Potassium-Exchanging ATPase; Symporters

2005
A possible role for membrane depolarization in epithelial wound healing.
    American journal of physiology. Cell physiology, 2005, Volume: 288, Issue:6

    Topics: Actins; Amiloride; Animals; Cattle; Cells, Cultured; Choline; Endothelium, Corneal; Epithelial Cells; Membrane Potentials; Sodium; Wound Healing

2005
Mechanisms behind Pb-induced disruption of Na+ and Cl- balance in rainbow trout (Oncorhynchus mykiss).
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 289, Issue:2

    Topics: Amiloride; Animals; Carbonic Anhydrases; Chlorides; Enzyme Inhibitors; Gills; Lead; Macrolides; Oncorhynchus mykiss; Proton-Translocating ATPases; Sodium; Sodium Channel Blockers; Sodium-Potassium-Exchanging ATPase; Time Factors; Water-Electrolyte Balance

2005
Interactions between Na+ channels and Na+-HCO3- cotransporters in the freshwater fish gill MR cell: a model for transepithelial Na+ uptake.
    American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Cell Survival; Epithelial Cells; Fluoresceins; Fluorescent Dyes; Gills; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channel Gating; Ion Transport; Membrane Potentials; Mitochondria; Models, Animal; Oncorhynchus mykiss; Sodium; Sodium Channels; Sodium-Bicarbonate Symporters

2007
Mechanisms of dietary Cu uptake in freshwater rainbow trout: evidence for Na-assisted Cu transport and a specific metal carrier in the intestine.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2007, Volume: 177, Issue:4

    Topics: Amiloride; Animals; Carbon Dioxide; Chlorides; Copper; Hydrogen-Ion Concentration; Hypercapnia; Intestinal Absorption; Intestinal Mucosa; Microvilli; Oncorhynchus mykiss; Osmolar Concentration; Osmotic Pressure; Silver; Sodium; Sodium Channel Blockers; Sulfates

2007
The small molecule phenamil induces osteoblast differentiation and mineralization.
    Molecular and cellular biology, 2009, Volume: 29, Issue:14

    Topics: Amiloride; Animals; Base Sequence; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 7; Bone Remodeling; Cell Cycle Proteins; Cell Differentiation; Cell Line; DNA Primers; Gene Expression; Mesenchymal Stem Cells; Mice; Minerals; Organ Culture Techniques; Osteoblasts; Recombinant Proteins; RNA, Small Interfering; Signal Transduction; Smad Proteins

2009
Ca(2+) regulation of endocochlear potential in marginal cells.
    The journal of physiological sciences : JPS, 2009, Volume: 59, Issue:5

    Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cochlea; Egtazic Acid; Endolymph; Epithelial Sodium Channels; Evoked Potentials, Auditory; Furosemide; Guinea Pigs; Imidazoles; Nifedipine; Sodium Channel Blockers; Sodium Potassium Chloride Symporter Inhibitors; Thapsigargin; TRPC Cation Channels

2009
The small molecule phenamil is a modulator of adipocyte differentiation and PPARgamma expression.
    Journal of lipid research, 2010, Volume: 51, Issue:9

    Topics: 3T3 Cells; Adipocytes; Amiloride; Animals; CCAAT-Enhancer-Binding Protein-delta; Cell Differentiation; DNA-Binding Proteins; Gene Expression Regulation; Harmine; Mice; Molecular Structure; Monoamine Oxidase Inhibitors; Oxazoles; PPAR gamma; Proto-Oncogene Proteins c-ets; Signal Transduction; Sodium Channel Blockers; Transcription Factors; Tyrosine

2010
The amiloride derivative phenamil attenuates pulmonary vascular remodeling by activating NFAT and the bone morphogenetic protein signaling pathway.
    Molecular and cellular biology, 2011, Volume: 31, Issue:3

    Topics: Acid Sensing Ion Channels; Amiloride; Animals; Base Sequence; Binding Sites; Bone Morphogenetic Proteins; Cell Proliferation; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Models, Biological; Molecular Sequence Data; Muscle Contraction; Nerve Tissue Proteins; NFATC Transcription Factors; Promoter Regions, Genetic; Protein Kinases; Protein Serine-Threonine Kinases; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Channels; Transcriptional Activation

2011
Cross-reactivity of acid-sensing ion channel and Na⁺-H⁺ exchanger antagonists with nicotinic acetylcholine receptors.
    The Journal of physiology, 2011, Nov-01, Volume: 589, Issue:Pt 21

    Topics: Acid Sensing Ion Channels; Amiloride; Animals; Brain; Cell Line; Guanidines; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Nicotine; Nicotinic Agonists; Oocytes; Pyrazoles; Receptors, Nicotinic; Sodium Channel Blockers; Sodium Channels; Sodium-Hydrogen Exchangers; Synaptic Transmission; Xenopus

2011
Pharmacological characterisation of apical Na+ and Cl- transport mechanisms of the anal papillae in the larval mosquito Aedes aegypti.
    The Journal of experimental biology, 2011, Dec-01, Volume: 214, Issue:Pt 23

    Topics: Aedes; Amiloride; Anal Canal; Animals; Bumetanide; Carbonic Anhydrases; Chlorides; Ion Transport; Ion-Selective Electrodes; Larva; Macrolides; Methazolamide; Microelectrodes; Models, Biological; Ouabain; Sodium; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Vacuolar Proton-Translocating ATPases

2011
Comparative characterization of Na+ transport in Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi: a model species complex for studying teleost invasion of freshwater.
    The Journal of experimental biology, 2012, Apr-01, Volume: 215, Issue:Pt 7

    Topics: Acclimatization; Amiloride; Animals; Cell Size; Chlorides; Epithelium; Fresh Water; Gills; Introduced Species; Ion Transport; Killifishes; Kinetics; Macrolides; Metolazone; Mitochondria; Models, Animal; Sodium; Species Specificity; Time Factors

2012
Evaluating the feasibility of utilizing the small molecule phenamil as a novel biofactor for bone regenerative engineering.
    Journal of tissue engineering and regenerative medicine, 2014, Volume: 8, Issue:9

    Topics: Alkaline Phosphatase; Amiloride; Animals; Biocompatible Materials; Bone Matrix; Bone Regeneration; Calcification, Physiologic; Cell Adhesion; Cell Line; Cell Proliferation; Feasibility Studies; Lactic Acid; Mice; Microspheres; Osteoblasts; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Small Molecule Libraries; Tissue Engineering; Tissue Scaffolds

2014
Short-term administration of small molecule phenamil induced a protracted osteogenic effect on osteoblast-like MC3T3-E1 cells.
    Journal of tissue engineering and regenerative medicine, 2016, Volume: 10, Issue:6

    Topics: Amiloride; Animals; Antigens, Differentiation; Cell Differentiation; Cell Line; Drug Carriers; Lactic Acid; Mice; Osteoblasts; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2016
Stimulating effects of quercetin and phenamil on differentiation of human dental pulp cells.
    European journal of oral sciences, 2013, Volume: 121, Issue:6

    Topics: Alkaline Phosphatase; Amiloride; Antioxidants; Cell Differentiation; Cells, Cultured; Dental Pulp; Dentinogenesis; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; MAP Kinase Signaling System; Osteoblasts; Osteocalcin; Phosphoproteins; Quercetin; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sialoglycoproteins

2013
Ammonia transport across the skin of adult rainbow trout (Oncorhynchus mykiss) exposed to high environmental ammonia (HEA).
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2014, Volume: 184, Issue:1

    Topics: Amiloride; Ammonia; Animals; Body Surface Area; Cation Transport Proteins; Environment; Fish Proteins; In Vitro Techniques; Oncorhynchus mykiss; Proton-Translocating ATPases; RNA, Messenger; Skin; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchangers

2014
Quorum sensing positively regulates flagellar motility in pathogenic Vibrio harveyi.
    Environmental microbiology, 2015, Volume: 17, Issue:4

    Topics: Amiloride; Animals; Aquatic Organisms; Artemia; Bacterial Proteins; Flagella; Quorum Sensing; Repressor Proteins; Sodium Channels; Trans-Activators; Transcription Factors; Vibrio; Virulence Factors

2015
An in vitro investigation of gastrointestinal Na(+) uptake mechanisms in freshwater rainbow trout.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2014, Volume: 184, Issue:8

    Topics: Amiloride; Animals; Biological Transport; Fresh Water; Furosemide; Gastrointestinal Tract; Hydrochlorothiazide; In Vitro Techniques; Kinetics; Macrolides; Models, Biological; Oncorhynchus mykiss; Osmolar Concentration; Osmoregulation; Regression Analysis; Sodium Radioisotopes

2014
Delivery of Phenamil Enhances BMP-2-Induced Osteogenic Differentiation of Adipose-Derived Stem Cells and Bone Formation in Calvarial Defects.
    Tissue engineering. Part A, 2015, Volume: 21, Issue:13-14

    Topics: Adipose Tissue; Amiloride; Animals; Bone Morphogenetic Protein 2; Bone Regeneration; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Lactic Acid; Mice, Inbred C57BL; Mice, Nude; Microscopy, Electron, Scanning; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skull; Smad Proteins; Stem Cells; Tissue Scaffolds; Ubiquitin-Protein Ligases; X-Ray Microtomography

2015
Cloning and characterization of Na(+)/H(+) Exchanger isoforms NHE2 and NHE3 from the gill of Pacific dogfish Squalus suckleyi.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2015, Volume: 188

    Topics: Amiloride; Animals; Biological Transport, Active; Cell Line; Cloning, Molecular; Cricetinae; Dogfish; Epithelial Sodium Channel Blockers; Fish Proteins; Gills; Inhibitory Concentration 50; Protein Isoforms; Sodium-Hydrogen Exchangers

2015
Enhanced Osteogenesis of Adipose-Derived Stem Cells by Regulating Bone Morphogenetic Protein Signaling Antagonists and Agonists.
    Stem cells translational medicine, 2016, Volume: 5, Issue:4

    Topics: Adipose Tissue; Adult Stem Cells; Amiloride; Animals; Bone Morphogenetic Proteins; Carrier Proteins; Cell Differentiation; Cells, Cultured; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Osteogenesis; Signal Transduction; Smad Proteins

2016
Re-Epithelialization of Pathological Cutaneous Wounds Is Improved by Local Mineralocorticoid Receptor Antagonism.
    The Journal of investigative dermatology, 2016, Volume: 136, Issue:10

    Topics: Administration, Cutaneous; Amiloride; Animals; Clobetasol; Epidermis; Glucocorticoids; Humans; Keratinocytes; Mice; Mineralocorticoid Receptor Antagonists; Ointments; Re-Epithelialization; Receptors, Mineralocorticoid; Skin; Wound Healing

2016
5-(N, N-Hexamethylene) amiloride is a GABA-A ρ1 receptor positive allosteric modulator.
    Channels (Austin, Tex.), 2016, Volume: 10, Issue:6

    Topics: Allosteric Regulation; Amiloride; Binding Sites; Electrophysiology; gamma-Aminobutyric Acid; Guanidine; HEK293 Cells; Humans; Mutagenesis, Site-Directed; Receptors, GABA-B

2016
Phenamil enhances the adipogenic differentiation of hen preadipocytes.
    Cell biology international, 2016, Volume: 40, Issue:10

    Topics: Adipocytes; Adipogenesis; Amiloride; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cells, Cultured; Chickens; Fatty Acid-Binding Proteins; Female; Oleic Acid; PPAR gamma

2016
Enhanced Mandibular Bone Repair by Combined Treatment of Bone Morphogenetic Protein 2 and Small-Molecule Phenamil.
    Tissue engineering. Part A, 2017, Volume: 23, Issue:5-6

    Topics: Amiloride; Animals; Bone Morphogenetic Protein 2; Drug Implants; Humans; Mandible; Mandibular Injuries; Mesenchymal Stem Cells; Rats, Sprague-Dawley

2017
Effects of Bioactive Compounds on Odontogenic Differentiation and Mineralization.
    Journal of dental research, 2017, Volume: 96, Issue:1

    Topics: Amiloride; Animals; Calcification, Physiologic; Dental Pulp; Dose-Response Relationship, Drug; Genistein; Metformin; Mice; Mice, Nude; Morpholines; Odontogenesis; Purines; Stem Cell Transplantation

2017
Phenamil, an amiloride derivative, restricts long bone growth and alters keeled-sternum bone architecture in growing chickens.
    Poultry science, 2017, Jul-01, Volume: 96, Issue:7

    Topics: Amiloride; Animal Feed; Animals; Avian Proteins; Calcification, Physiologic; Chickens; Female; Male; Osteogenesis; Sternum; Tibia

2017
Intracellular co-delivery of Sr ion and phenamil drug through mesoporous bioglass nanocarriers synergizes BMP signaling and tissue mineralization.
    Acta biomaterialia, 2017, 09-15, Volume: 60

    Topics: Amiloride; Bone Morphogenetic Proteins; Calcification, Physiologic; Cell Culture Techniques; Cells, Cultured; Drug Carriers; Humans; Mesenchymal Stem Cells; Nanoparticles; Odontogenesis; Osteogenesis; Porosity; Signal Transduction; Strontium

2017
Small molecule-mediated tribbles homolog 3 promotes bone formation induced by bone morphogenetic protein-2.
    Scientific reports, 2017, 08-08, Volume: 7, Issue:1

    Topics: Adipogenesis; Amiloride; Animals; Bone Density Conservation Agents; Bone Morphogenetic Protein 2; Bone Regeneration; Cell Differentiation; Drug Synergism; Drug Therapy, Combination; Enzyme Activation; Gene Expression Regulation; Inflammation; Male; Mandible; Mandibular Injuries; Mesenchymal Stem Cells; NF-kappa B; Osteoblasts; Osteogenesis; PPAR gamma; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Treatment Outcome

2017
Sodium-powered stators of the bacterial flagellar motor can generate torque in the presence of phenamil with mutations near the peptidoglycan-binding region.
    Molecular microbiology, 2019, Volume: 111, Issue:6

    Topics: Amiloride; ATP-Binding Cassette Transporters; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Flagella; Molecular Motor Proteins; Peptidoglycan; Phylogeny; Point Mutation; Sodium; Sodium Channel Blockers; Sodium Channels; Torque; Vibrio alginolyticus

2019
Enhanced Cellular Uptake Of Phenamil Through Inclusion Complex With Histidine Functionalized β-Cyclodextrin As Penetrative Osteoinductive Agent.
    International journal of nanomedicine, 2019, Volume: 14

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adipose Tissue; Amiloride; Calcification, Physiologic; Cell Survival; Endocytosis; Histidine; Humans; Molecular Docking Simulation; Osseointegration; Osteogenesis; Particle Size; Proton Magnetic Resonance Spectroscopy; Solubility; Spectroscopy, Fourier Transform Infrared; Static Electricity; Stem Cells

2019
Mineralized nanofibrous scaffold promotes phenamil-induced osteoblastic differentiation while mitigating adipogenic differentiation.
    Journal of tissue engineering and regenerative medicine, 2020, Volume: 14, Issue:3

    Topics: Adipogenesis; Amiloride; Animals; Cell Differentiation; Cell Line; Mice; Nanofibers; Osteoblasts; Tissue Scaffolds

2020
One-pot porogen free method fabricated porous microsphere-aggregated 3D PCL scaffolds for bone tissue engineering.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2020, Volume: 108, Issue:6

    Topics: Amiloride; Apatites; Biocompatible Materials; Bone Morphogenetic Protein 2; Bone Regeneration; Cell Differentiation; Cell Survival; Drug Liberation; Gene Expression; Humans; Microspheres; Nanostructures; Polyesters; Porosity; Recombinant Proteins; Tissue Engineering; Tissue Scaffolds; Transforming Growth Factor beta

2020
An Elastic Mineralized 3D Electrospun PCL Nanofibrous Scaffold for Drug Release and Bone Tissue Engineering.
    ACS applied bio materials, 2021, 04-19, Volume: 4, Issue:4

    Topics: Amiloride; Animals; Bone Regeneration; Cell Differentiation; Cell Line; Durapatite; Elastic Modulus; Extracellular Matrix; Mice; Minerals; Nanofibers; Osteoclasts; Osteogenesis; Polyesters; Porosity; Printing, Three-Dimensional; Serum Albumin, Bovine; Surface Properties; Tissue Engineering

2021
Dual drug delivery system of teicoplanin and phenamil based on pH-sensitive silk fibroin/sodium alginate hydrogel scaffold for treating chronic bone infection.
    Biomaterials advances, 2022, Volume: 139

    Topics: Alginates; Amiloride; Animals; Anti-Bacterial Agents; Drug Delivery Systems; Fibroins; Hydrogels; Hydrogen-Ion Concentration; Methicillin-Resistant Staphylococcus aureus; Osteomyelitis; Rats; Teicoplanin

2022