Page last updated: 2024-08-21

amiloride and methyldopa

amiloride has been researched along with methyldopa in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199013 (56.52)18.7374
1990's1 (4.35)18.2507
2000's3 (13.04)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Avdeef, A; Tam, KY1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Goldet, L; Jouve, A; Mathieu, M1
Bernardi, P; Bobba, P; Croce, L; Dalla Torre, M; Di Benedetto, A; Galassi, A; Lombardo, M; Masacci, E; Montemartini, C; Mussari, A; Ricciardi, S; Santucci, F1
Diakos, A; Kontoyannis, DA; Kontoyannis, SA; Moulopoulos, SD; Sideris, DA1
Fidel, J; Glikberg, F1
Dzúrik, R; Dzúriková, V; Krechnáková, A; Szalayová, V1
Brunner, HR; Graf, HJ; Jaussi, A; Porchet, M; Rion, F; Waeber, B1
Naidoo, DN; Seedat, YK1
Hilewitz, H; Rogel, S; Weinstein, M1
Bolzano, K; Krempler, F; Sandhofer, F1
Obel, AO1
Hwang, IK; Moncloa, F; Muccilli, AC1
Boehringer, K; Meier, A; Mordasini, R; Riesen, W; Schiffl, H; Weidmann, P1
Assandri, J; Cobelli, F; Opasich, C; Vecchio, C1
Hall, DR; Odendaal, HJ1
Agatonovic-Kustrin, S; Minic, D; Zecević, M; Zivanović, L1
Agbani, EO; Bolaji, EE; Erhun, WO1

Reviews

1 review(s) available for amiloride and methyldopa

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

8 trial(s) available for amiloride and methyldopa

ArticleYear
Results of a national therapeutic trial conducted in 10,000 hypertensive patients by 2000 general practitioners.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Drug Tolerance; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Timolol

1978
[Usefulness of ambulatory registration of arterial pressure in therapeutic trials of antihypertensive agents].
    Schweizerische medizinische Wochenschrift, 1985, Dec-14, Volume: 115, Issue:50

    Topics: Adult; Aged; Ambulatory Care; Amiloride; Antihypertensive Agents; Blood Pressure Determination; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Private Practice; Timolol

1985
[A combination of methyldopa, hydrochlorothiazide and amiloride in the treatment of essential hypertension].
    Acta medica Austriaca, 1984, Volume: 11, Issue:2

    Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Posture; Pulse; Pyrazines; Urea; Uric Acid

1984
A comparison of timolol plus hydrochlorothiazide plus amiloride and methyldopa in essential hypertension in Black Africans.
    Tropical and geographical medicine, 1983, Volume: 35, Issue:3

    Topics: Adult; Amiloride; Antihypertensive Agents; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Kenya; Male; Methyldopa; Middle Aged; Pyrazines; Random Allocation; Timolol

1983
Multiclinic evaluation of the antihypertensive effect of a methyldopa, hydrochlorothiazine, and amiloride combination.
    Clinical therapeutics, 1980, Volume: 3, Issue:3

    Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Pyrazines; Random Allocation; Time Factors

1980
[The effect of hydrochlorothiazide/amiloride alone or in combination with alpha-methyldopa on serum lipoproteins].
    Schweizerische medizinische Wochenschrift, 1981, Apr-11, Volume: 111, Issue:15

    Topics: Adult; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Methyldopa; Pyrazines

1981
The addition of a diuretic to anti-hypertensive therapy for early severe hypertension in pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1998, Volume: 60, Issue:1

    Topics: Adult; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Gestational Age; Humans; Hydrochlorothiazide; Hypertension; Length of Stay; Methyldopa; Nifedipine; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Treatment Outcome

1998
Positive benefits of a pharmacist-managed hypertension clinic in Nigeria.
    Public health, 2005, Volume: 119, Issue:9

    Topics: Aged; Amiloride; Antihypertensive Agents; Community Health Centers; Counseling; Diuretics; Drug Monitoring; Drug Therapy, Combination; Female; Health Services Accessibility; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Nigeria; Patient Education as Topic; Pharmacists; Program Evaluation; Treatment Outcome

2005

Other Studies

14 other study(ies) available for amiloride and methyldopa

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[The combination of hydrochlorothiazide, amiloride and alpha-methyldopa in the treatment of arterial hypertension. Clinical evaluation of a multicentric study].
    Minerva cardioangiologica, 1979, Volume: 27, Issue:12

    Topics: Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines

1979
Antihypertensive treatment for the management of premature ventricular complexes. Pilot study.
    Acta cardiologica, 1988, Volume: 43, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Infusions, Intravenous; Male; Metaraminol; Methyldopa; Middle Aged; Nitroprusside

1988
The effect of a single daily low dose of methyldopa and K+ sparing diuretic on blood pressure in the elderly.
    The British journal of clinical practice, 1988, Volume: 42, Issue:12

    Topics: Aged; Aged, 80 and over; Amiloride; Blood Pressure; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged

1988
[Combination of methyldopa and diuretics in the treatment of hypertensive disease].
    Vnitrni lekarstvi, 1985, Volume: 31, Issue:1

    Topics: Aged; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines

1985
Evaluation of amiloride combined with hydrochlorothiazide (Moduretic) in the treatment of hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Jul-21, Volume: 47, Issue:28

    Topics: Adult; Aged; Amiloride; Benzothiadiazines; Diuretics; Drug Combinations; Female; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Propranolol; Pyrazines; Urea; Uremia

1973
The effect of single-dose methyldopa and diuretic on BP and left ventricular mass.
    Archives of internal medicine, 1984, Volume: 144, Issue:8

    Topics: Adult; Aged; Amiloride; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines; Stroke Volume; Time Factors

1984
[The syndrome of hypertension of effort in the rehabilitation of patients with recent myocardial infarct. Problems of drug therapy].
    Bollettino della Societa italiana di cardiologia, 1980, Volume: 25, Issue:5

    Topics: Amiloride; Antihypertensive Agents; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Infarction; Physical Exertion

1980
The use of a response surface methodology on HPLC analysis of methyldopa, amiloride and hydrochlorothiazide in tablets.
    Journal of pharmaceutical and biomedical analysis, 2001, Volume: 24, Issue:5-6

    Topics: Amiloride; Calibration; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Methyldopa; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tablets

2001