Page last updated: 2024-08-21

amiloride and metformin

amiloride has been researched along with metformin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's8 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Blomgren, A; Börjesson, L; Gustavsson, L; Hendrickx, R; Jenvert, RM; Johansson, JG; Lohmann, C1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Saito, T; Yoshida, S1
Baines, DL; Hardie, DG; Kalsi, KK; Mustard, KJ; Pellatt, LJ; Pucovsky, V; Scott, JW; Sivagnanasundaram, J; Woollhead, AM1
Albert, AP; Baines, DL; Mace, OJ; Woollhead, AM1
Hong, C; Kang, MK; Kim, RH; Lee, C; Park, NH; Phung, S; Shin, KH; Song, M; Stevenson, RG; Yi, JK1

Reviews

2 review(s) available for amiloride and metformin

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for amiloride and metformin

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Identification of novel substrates and structure-activity relationship of cellular uptake mediated by human organic cation transporters 1 and 2.
    Journal of medicinal chemistry, 2013, Sep-26, Volume: 56, Issue:18

    Topics: Biological Transport; Chemical Phenomena; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Pharmaceutical Preparations; Reproducibility of Results; Structure-Activity Relationship; Substrate Specificity

2013
Effects of biguanides on short-circuit current in frog skin.
    The American journal of physiology, 1984, Volume: 247, Issue:2 Pt 2

    Topics: Amiloride; Animals; Biguanides; Buformin; Galvanic Skin Response; Metformin; Mucous Membrane; Phenformin; Rana pipiens; Serous Membrane; Skin; Sodium; Time Factors

1984
Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells.
    British journal of pharmacology, 2007, Volume: 151, Issue:8

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Amiloride; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cell Line; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelial Sodium Channels; Fluorescence; Humans; Hypoglycemic Agents; Lung; Metformin; Microscopy, Confocal; Multienzyme Complexes; Ouabain; Phenformin; Protein Serine-Threonine Kinases; Ribonucleotides; Sodium

2007
AICAR decreases the activity of two distinct amiloride-sensitive Na+-permeable channels in H441 human lung epithelial cell monolayers.
    American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:5

    Topics: Amiloride; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biophysical Phenomena; Cell Line; Cell Membrane; Cyclic Nucleotide-Gated Cation Channels; Epithelial Cells; Epithelial Sodium Channels; Humans; Ion Channel Gating; Lung; Metformin; Patch-Clamp Techniques; Permeability; Ribonucleotides

2008
Effects of Bioactive Compounds on Odontogenic Differentiation and Mineralization.
    Journal of dental research, 2017, Volume: 96, Issue:1

    Topics: Amiloride; Animals; Calcification, Physiologic; Dental Pulp; Dose-Response Relationship, Drug; Genistein; Metformin; Mice; Mice, Nude; Morpholines; Odontogenesis; Purines; Stem Cell Transplantation

2017