Page last updated: 2024-08-21

amiloride and lactic acid

amiloride has been researched along with lactic acid in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19907 (15.91)18.7374
1990's15 (34.09)18.2507
2000's12 (27.27)29.6817
2010's9 (20.45)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Best, L; Tomlinson, S; Trebilcock, R1
Arnolda, L; Aronson, JK; Grahame-Smith, DG; Green, Y; Radda, GK; Syme, PD1
McBride, DE; McLaughlin, ML; Perrone, RD1
Broxterman, HJ; Kuiper, CM; Lankelma, J; Pinedo, HM; Schuurhuis, GJ1
Hundal, HS; Kuret, CM; MacLennan, PA; Rennie, MJ; Watt, PW1
Vaughan-Jones, RD1
Tokuda, H; Udagawa, T; Unemoto, T1
Doppler, W; Grunicke, H; Maly, K1
Brezis, M; Epstein, FH; Silva, P; Spokes, K1
Boonstra, J; de Laat, SW; Moolenaar, WH; van der Saag, PT1
Agius, L; Tosh, D1
Moffat, MP; Ward, CA1
Bernard, M; Cozzone, P; Feuvray, D; Khandoudi, N1
Allen, DG; Turvey, SE1
Cragoe, EJ; Soler, C; Soley, M1
Kemp, GJ; Radda, GK; Sanderson, AL; Thompson, CH1
Karmazyn, M1
Hoque, AN; Karmazyn, M1
Bird, I; Farnoud, R; Montcourrier, P; Rochefort, H; Silver, I1
Davies, SE; Gotoh, M; Obrenovitch, TP1
Boutellier, S; Lutz, TA; Scharrer, E; Sutter, D; Volkert, M; Wild, S1
Baethmann, A; Haberstok, J; Kölbl, I; Peters, J; Plesnila, N; Staub, F1
Albarani, V; Bellizzi, A; Casavola, V; Guerra, L; Paradiso, A; Reshkin, SJ; Tommasino, M1
O'Regan, MH; Phillis, JW; Ren, J1
del Nido, PJ; McGowan, FX; Simplaceanu, E; Takeuchi, K; Tsushima, T1
Benos, DJ; Ji, HL1
Gitterman, DP; Randall, AD; Wilson, J1
Fernández, MA; García, JV; Marina Prendes, MG; Perazzo, JC; Savino, EA; Testoni, G; Varela, A1
McCleskey, EW; Naves, LA; Wenk, HN; Yagi, J1
Hayes, SG; Kaufman, MP; Kindig, AE1
Fernández, MA; González, M; Perazzo, JC; Prendes, MG; Savino, EA; Torresín, E; Varela, A1
Hughen, RW; Lee, J; Light, AR; Liu, Z; Rainier, J; Zhang, J1
Hayes, SG; Kaufman, MP; McCord, JL1
Arreola, J; Kaba, NK; Kim, M; Knauf, PA; Law, FY; Lefort, CT; Martel-Gallegos, G; Schultz, J; Waugh, RE1
Bonanno, JA; Nguyen, TT1
Kaufman, MP; McCord, JL; Tsuchimochi, H; Yamauchi, K1
Ashe, KM; Kan, HM; Laurencin, CT; Lo, KW; Ulery, BD1
Bainbridge, A; Cady, E; Chandrasekaran, M; Cheong, J; Faulkner, S; Hristova, M; Iwata, O; Iwata, S; Kapetanakis, A; Kato, T; Raivich, G; Robertson, NJ1
Chen, Y; Dong, Q; Feng, J; Gu, T; Kong, W; Sun, Y; Wang, M; Wu, Y; Yang, X; Zhang, Y1
Kan, HM; Laurencin, CT; Lo, KW1
Delay, ER; Kondoh, T1
Aghaloo, T; Bezouglaia, O; Cui, ZK; Fan, J; Fartash, A; Guo, M; Im, CS; Lee, JY; Lee, M; Nguyen, J; Wu, BM1
Barber, DL; Kisor, K; Manoli, SS; Webb, BA1

Other Studies

44 other study(ies) available for amiloride and lactic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Lactate transport in insulin-secreting beta-cells: contrast between rat islets and HIT-T15 insulinoma cells.
    Molecular and cellular endocrinology, 1992, Volume: 86, Issue:1-2

    Topics: 4-Chloromercuribenzenesulfonate; Amiloride; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Coumaric Acids; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Lactates; Lactic Acid; Monocarboxylic Acid Transporters; Pancreatic Neoplasms; Quercetin; Rats; Tumor Cells, Cultured

1992
Evidence for increased in vivo Na(+)-H+ antiporter activity and an altered skeletal muscle contractile response in the spontaneously hypertensive rat.
    Journal of hypertension, 1990, Volume: 8, Issue:11

    Topics: Amiloride; Animals; Carrier Proteins; Cytosol; Glycogen; Hypertension; Isometric Contraction; Lactates; Lactic Acid; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Hydrogen Exchangers

1990
Secondary hyperaldosteronism stimulates acidification in rat distal colon.
    Pflugers Archiv : European journal of physiology, 1990, Volume: 416, Issue:6

    Topics: Adenosine Triphosphatases; Amiloride; Animals; Carrier Proteins; Colon; Diet; Electric Stimulation; Hydrogen; Hydrogen-Ion Concentration; Hyperaldosteronism; Lactates; Lactic Acid; Male; Membrane Potentials; Ouabain; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers; Vanadates

1990
Glycolysis in P-glycoprotein-overexpressing human tumor cell lines. Effects of resistance-modifying agents.
    FEBS letters, 1989, Apr-24, Volume: 247, Issue:2

    Topics: Adenosine Triphosphate; Amiloride; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Proteins; Chloroquine; Cytochalasin B; Drug Resistance; Energy Metabolism; Glutathione Transferase; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Membrane Glycoproteins; Monensin; Nigericin; Oxygen Consumption; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil

1989
L(+)-lactate transport in perfused rat skeletal muscle: kinetic characteristics and sensitivity to pH and transport inhibitors.
    Biochimica et biophysica acta, 1988, Oct-06, Volume: 944, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Chloromercuribenzenesulfonate; Amiloride; Animals; Carrier Proteins; Cinnamates; Coumaric Acids; Female; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Monocarboxylic Acid Transporters; Muscles; Perfusion; Rats; Rats, Inbred Strains

1988
Regulation of intracellular pH in cardiac muscle.
    Ciba Foundation symposium, 1988, Volume: 139

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acid-Base Equilibrium; Amiloride; Ammonium Chloride; Animals; Carrier Proteins; Cell Membrane; Chloride-Bicarbonate Antiporters; Glycolysis; Guinea Pigs; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Myocardium; Protons; Sarcolemma; Sheep; Sodium-Hydrogen Exchangers

1988
Generation of Na+ electrochemical potential by the Na+-motive NADH oxidase and Na+/H+ antiport system of a moderately halophilic Vibrio costicola.
    The Journal of biological chemistry, 1986, Feb-25, Volume: 261, Issue:6

    Topics: Amiloride; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carrier Proteins; Electrochemistry; Lactates; Lactic Acid; Membrane Potentials; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxygen Consumption; Sodium; Sodium-Hydrogen Exchangers; Tetraethylammonium Compounds; Valinomycin; Vibrio

1986
Role of the Na+/H+ antiport in the regulation of the internal pH of Ehrlich ascites tumor cells in culture.
    The Journal of membrane biology, 1986, Volume: 91, Issue:2

    Topics: Amiloride; Animals; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Carrier Proteins; Cell Division; Cells, Cultured; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Mice; Protons; Sodium; Sodium-Hydrogen Exchangers

1986
Lactate increases potassium secretion by perfused rat kidney.
    The American journal of physiology, 1986, Volume: 251, Issue:5 Pt 2

    Topics: Amiloride; Animals; Anions; In Vitro Techniques; Kidney; Lactates; Lactic Acid; Perfusion; Potassium; Rats; Stimulation, Chemical

1986
Sodium/proton exchange in mouse neuroblastoma cells.
    The Journal of biological chemistry, 1981, Dec-25, Volume: 256, Issue:24

    Topics: Amiloride; Animals; Anions; Biological Transport, Active; Cell Line; Hydrogen-Ion Concentration; Ion Exchange; Lactates; Lactic Acid; Mice; Monensin; Neuroblastoma; Sodium

1981
Lactate and pyruvate stimulate the conversion of glucose to glycogen in hepatocytes by a mechanism that does not involve gluconeogenic flux.
    Biochimica et biophysica acta, 1995, Aug-31, Volume: 1268, Issue:2

    Topics: Amiloride; Animals; Glucose; Glycogen; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Male; Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1995
Modulation of sodium-hydrogen exchange activity in cardiac myocytes during acidosis and realkalinisation: effects on calcium, pHi, and cell shortening.
    Cardiovascular research, 1995, Volume: 29, Issue:2

    Topics: Acidosis; Amiloride; Animals; Calcium; Cell Size; Cells, Cultured; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Myocardium; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1995
Mechanisms of intracellular pH regulation during postischemic reperfusion of diabetic rat hearts.
    Diabetes, 1995, Volume: 44, Issue:2

    Topics: Amiloride; Animals; Bicarbonates; Diabetes Mellitus, Experimental; HEPES; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Wistar; Sarcolemma; Sodium-Hydrogen Exchangers; Ventricular Function, Left

1995
Changes in myoplasmic sodium concentration during exposure to lactate in perfused rat heart.
    Cardiovascular research, 1994, Volume: 28, Issue:7

    Topics: Amiloride; Animals; Benzofurans; Ethers, Cyclic; Female; Fluorescent Dyes; Hydrogen-Ion Concentration; In Vitro Techniques; Indicators and Reagents; Lactates; Lactic Acid; Myocardium; Myofibrils; Perfusion; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers

1994
Effects of epidermal growth factor on gluconeogenesis and cellular redox state do not require Na+/H+ exchange or Na+/K(+)-ATPase activities.
    Regulatory peptides, 1994, Jun-16, Volume: 52, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amiloride; Animals; Cell Survival; Cells, Cultured; Epidermal Growth Factor; Gluconeogenesis; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Male; Ouabain; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase

1994
pH control in rat skeletal muscle during exercise, recovery from exercise, and acute respiratory acidosis.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis, Respiratory; Acute Disease; Adenosine Diphosphate; Amiloride; Animals; Buffers; Carbon Dioxide; Carbonates; Electric Stimulation; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Muscles; Phosphocreatine; Phosphorus; Physical Exertion; Rats; Rats, Wistar; Rest; Sciatic Nerve

1994
Na+/H+ exchange inhibitors reverse lactate-induced depression in postischaemic ventricular recovery.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Amiloride; Animals; Carrier Proteins; Heart; Hydrogen; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers

1993
Effect of sodium-hydrogen exchange inhibition on functional and metabolic impairment produced by oxidative stress in the isolated rat heart.
    Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:4

    Topics: Amiloride; Animals; Free Radicals; Glycogen; Guanidines; Heart; Hydrogen Peroxide; In Vitro Techniques; Lactic Acid; Male; Myocardium; Oxidants; Oxidative Stress; Purines; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones; Xanthine Oxidase

1997
Breast cancer cells have a high capacity to acidify extracellular milieu by a dual mechanism.
    Clinical & experimental metastasis, 1997, Volume: 15, Issue:4

    Topics: Acids; Amiloride; Anti-Bacterial Agents; Breast; Breast Neoplasms; Cells, Cultured; Extracellular Space; Glucose; Humans; Hydrogen-Ion Concentration; Lactic Acid; Macrolides; Macrophages; Microelectrodes; Oligomycins; Proton Pump Inhibitors; Proton-Translocating ATPases; Tumor Cells, Cultured

1997
Brain tissue acidosis: effects on the extracellular concentration of N-acetylaspartate.
    Journal of neurochemistry, 1997, Volume: 69, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis; Amiloride; Ammonium Chloride; Animals; Aspartic Acid; Brain; Electric Conductivity; Extracellular Space; Hydrogen-Ion Concentration; Hypercapnia; Lactic Acid; Male; Microdialysis; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley

1997
Hyperpolarization of the cell membrane of mouse hepatocytes by lactate, pyruvate, and fructose is due to Ca2+-dependent activation of K+ channels and of the Na+/K+-ATPase.
    Biochimica et biophysica acta, 1998, Jul-17, Volume: 1372, Issue:2

    Topics: Amiloride; Animals; Calcium; Cell Membrane; Electrophysiology; Enzyme Activation; Enzyme Inhibitors; Female; Fructose; Gluconeogenesis; Lactic Acid; Liver; Mice; Mice, Inbred ICR; Ouabain; Potassium Channel Blockers; Potassium Channels; Pyruvic Acid; Sodium-Potassium-Exchanging ATPase; Tetraethylammonium; Thapsigargin

1998
Effect of lactacidosis on cell volume and intracellular pH of astrocytes.
    Journal of neurotrauma, 1999, Volume: 16, Issue:9

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acidosis; Amiloride; Animals; Animals, Newborn; Astrocytes; Cell Size; Cells, Cultured; Diuretics; Hydrogen-Ion Concentration; Intracellular Fluid; Lactic Acid; Rats; Rats, Sprague-Dawley

1999
Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation.
    The Journal of biological chemistry, 2000, Feb-25, Volume: 275, Issue:8

    Topics: Adenosine Triphosphate; Amiloride; Ammonium Chloride; Androstadienes; Blood; Blotting, Western; Breast Neoplasms; Cell Line; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Sodium-Hydrogen Exchangers; Time Factors; Transfection; Tumor Cells, Cultured; Up-Regulation; Wortmannin

2000
Inhibition of Na(+)/H(+) exchange by 5-(N-ethyl-N-isopropyl)-amiloride reduces free fatty acid efflux from the ischemic reperfused rat cerebral cortex.
    Brain research, 2000, Nov-24, Volume: 884, Issue:1--2

    Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cardiovascular Physiological Phenomena; Cerebral Cortex; Electroencephalography; Fatty Acids, Nonesterified; Glucose; Lactic Acid; Male; Neuroprotective Agents; Phospholipases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Hydrogen Exchangers

2000
L-arginine potentiates negative inotropic and metabolic effects to myocardium partly through the amiloride sensitive mechanism.
    The Japanese journal of physiology, 2002, Volume: 52, Issue:2

    Topics: Adenosine Triphosphate; Amiloride; Animals; Arginine; Blood Pressure; Caustics; Diuretics; Drug Synergism; Energy Metabolism; Glucose; Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Lysine; Myocardial Contraction; Myocardium; Nitric Oxide; Oxygen Consumption; Perfusion; Rabbits; Sodium Hydroxide; Sodium-Hydrogen Exchangers

2002
Degenerin sites mediate proton activation of deltabetagamma-epithelial sodium channel.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Acid Sensing Ion Channels; Amiloride; Amino Acid Substitution; Animals; Degenerin Sodium Channels; Edetic Acid; Epithelial Sodium Channels; Formates; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Channels; Lactic Acid; Membrane Potentials; Nerve Tissue Proteins; Oocytes; Patch-Clamp Techniques; Protein Subunits; Protons; Pyruvic Acid; Recombinant Proteins; Sodium; Sodium Channels; Structure-Activity Relationship; Xenopus

2004
Functional properties and pharmacological inhibition of ASIC channels in the human SJ-RH30 skeletal muscle cell line.
    The Journal of physiology, 2005, Feb-01, Volume: 562, Issue:Pt 3

    Topics: Acid Sensing Ion Channels; Acids; Amiloride; Cell Line; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Lactic Acid; Membrane Potentials; Membrane Proteins; Muscle Fibers, Skeletal; Nerve Tissue Proteins; Peptides; Protein Subunits; Sodium Channels; Spider Venoms

2005
Influence of fasting on the effects of dimethylamiloride and oxfenicine on ischaemic-reperfused rat hearts.
    Archives of physiology and biochemistry, 2006, Volume: 112, Issue:1

    Topics: Amiloride; Animals; Carnitine O-Palmitoyltransferase; Cell Survival; Enzyme Inhibitors; Fasting; Fatty Acids; Female; Glycine; Glycolysis; In Vitro Techniques; Ion Transport; Ischemic Preconditioning, Myocardial; Lactic Acid; Lipid Metabolism; Male; Muscle Cells; Myocardial Contraction; Myocardial Ischemia; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury

2006
Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia.
    Circulation research, 2006, Sep-01, Volume: 99, Issue:5

    Topics: Acid Sensing Ion Channels; Amiloride; Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Electric Conductivity; Heart; Hydrogen-Ion Concentration; Lactic Acid; Membrane Proteins; Myocardial Ischemia; Nerve Tissue Proteins; Neurons, Afferent; Protons; Rats; Sodium Channel Blockers; Sodium Channels

2006
Blockade of acid sensing ion channels attenuates the exercise pressor reflex in cats.
    The Journal of physiology, 2007, Jun-15, Volume: 581, Issue:Pt 3

    Topics: Acid Sensing Ion Channels; Action Potentials; Amiloride; Animals; Blood Pressure; Capsaicin; Cats; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Lactic Acid; Membrane Proteins; Muscle Contraction; Muscle, Skeletal; Nerve Tissue Proteins; Neural Conduction; Neurons, Afferent; Physical Exertion; Reflex; Reflex, Stretch; Sodium Channels

2007
Protection of ischaemic-reperfused rat heart by dimethylamiloride is associated with inhibition of mitochondrial permeability transition.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:2

    Topics: Amiloride; Animals; Cardiovascular Agents; Cell Survival; Cyclosporine; Female; Glycolysis; In Vitro Techniques; Lactic Acid; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Perfusion; Permeability; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Time Factors; Ventricular Function, Left; Ventricular Pressure

2008
Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1.
    Journal of neurophysiology, 2008, Volume: 100, Issue:3

    Topics: Acid Sensing Ion Channels; Adenosine Triphosphate; Amiloride; Analysis of Variance; Animals; Calcium; Capsaicin; Cells, Cultured; Cnidarian Venoms; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Hydrogen-Ion Concentration; Lactic Acid; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Nerve Tissue Proteins; Neurons; Protons; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Sodium Channels; TRPV Cation Channels

2008
Acid-sensing ion and epithelial sodium channels do not contribute to the mechanoreceptor component of the exercise pressor reflex.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:3

    Topics: Acid Sensing Ion Channels; Amiloride; Animals; Blood Pressure; Cats; Decerebrate State; Diuretics; Epithelial Cells; Epithelial Sodium Channels; Female; Heart Rate; Kidney; Lactic Acid; Male; Mechanoreceptors; Muscle Contraction; Nerve Tissue Proteins; Physical Exertion; Sodium Channels; Tendons

2008
Inhibition of Na+/H+ exchanger enhances low pH-induced L-selectin shedding and beta2-integrin surface expression in human neutrophils.
    American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:5

    Topics: Amiloride; Ammonium Chloride; CD11b Antigen; CD18 Antigens; Cell Membrane; Guanidines; Humans; Hydrogen-Ion Concentration; L-Selectin; Lactic Acid; Macrophage-1 Antigen; Metalloproteases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Kinase Inhibitors; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones; Time Factors

2008
Bicarbonate, NBCe1, NHE, and carbonic anhydrase activity enhance lactate-H+ transport in bovine corneal endothelium.
    Investigative ophthalmology & visual science, 2011, Oct-17, Volume: 52, Issue:11

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Blotting, Western; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cattle; Cells, Cultured; Endothelium, Corneal; Fluorescent Antibody Technique, Indirect; Hydrogen-Ion Concentration; Lactic Acid; Monocarboxylic Acid Transporters; Niflumic Acid; Real-Time Polymerase Chain Reaction; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers

2011
Blockade of acid sensing ion channels attenuates the augmented exercise pressor reflex in rats with chronic femoral artery occlusion.
    The Journal of physiology, 2011, Dec-15, Volume: 589, Issue:Pt 24

    Topics: Acid Sensing Ion Channels; Amiloride; Animals; Baroreflex; Blood Pressure; Capsaicin; Cnidarian Venoms; Femoral Artery; Heart Rate; Hindlimb; Lactic Acid; Ligation; Male; Muscle Contraction; Muscle, Skeletal; Nerve Tissue Proteins; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sodium Channel Agonists; Sodium Channel Blockers; Sodium Channels

2011
Evaluating the feasibility of utilizing the small molecule phenamil as a novel biofactor for bone regenerative engineering.
    Journal of tissue engineering and regenerative medicine, 2014, Volume: 8, Issue:9

    Topics: Alkaline Phosphatase; Amiloride; Animals; Biocompatible Materials; Bone Matrix; Bone Regeneration; Calcification, Physiologic; Cell Adhesion; Cell Line; Cell Proliferation; Feasibility Studies; Lactic Acid; Mice; Microspheres; Osteoblasts; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Small Molecule Libraries; Tissue Engineering; Tissue Scaffolds

2014
Methyl-isobutyl amiloride reduces brain Lac/NAA, cell death and microglial activation in a perinatal asphyxia model.
    Journal of neurochemistry, 2013, Volume: 124, Issue:5

    Topics: Amiloride; Animals; Aspartic Acid; Asphyxia; Brain; Cell Death; Disease Models, Animal; Hypoxia-Ischemia, Brain; Immunohistochemistry; In Situ Nick-End Labeling; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Microglia; Neuroprotective Agents; Swine

2013
Preparation, characterization, and in vitro and in vivo investigation of chitosan-coated poly (d,l-lactide-co-glycolide) nanoparticles for intestinal delivery of exendin-4.
    International journal of nanomedicine, 2013, Volume: 8

    Topics: Amiloride; Animals; Cell Survival; Chitosan; Chlorpromazine; Dogs; Drug Carriers; Exenatide; Intestinal Absorption; Lactic Acid; Madin Darby Canine Kidney Cells; Male; Models, Biological; Nanoparticles; Particle Size; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Spectrometry, Fluorescence; Venoms

2013
Short-term administration of small molecule phenamil induced a protracted osteogenic effect on osteoblast-like MC3T3-E1 cells.
    Journal of tissue engineering and regenerative medicine, 2016, Volume: 10, Issue:6

    Topics: Amiloride; Animals; Antigens, Differentiation; Cell Differentiation; Cell Line; Drug Carriers; Lactic Acid; Mice; Osteoblasts; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2016
Dried bonito dashi: taste qualities evaluated using conditioned taste aversion methods in wild-type and T1R1 knockout mice.
    Chemical senses, 2015, Volume: 40, Issue:2

    Topics: Amiloride; Amino Acids; Animals; Avoidance Learning; Citric Acid; Conditioning, Classical; Cooking; Dose-Response Relationship, Drug; Food; Glutamic Acid; Hydrogen-Ion Concentration; Inosine Monophosphate; Lactic Acid; Male; Mice, Inbred C57BL; Mice, Knockout; Quinine; Receptors, G-Protein-Coupled; Sodium Glutamate; Sucrose; Taste Perception

2015
Delivery of Phenamil Enhances BMP-2-Induced Osteogenic Differentiation of Adipose-Derived Stem Cells and Bone Formation in Calvarial Defects.
    Tissue engineering. Part A, 2015, Volume: 21, Issue:13-14

    Topics: Adipose Tissue; Amiloride; Animals; Bone Morphogenetic Protein 2; Bone Regeneration; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Lactic Acid; Mice, Inbred C57BL; Mice, Nude; Microscopy, Electron, Scanning; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skull; Smad Proteins; Stem Cells; Tissue Scaffolds; Ubiquitin-Protein Ligases; X-Ray Microtomography

2015
Ethyl isopropyl amiloride decreases oxidative phosphorylation and increases mitochondrial fusion in clonal untransformed and cancer cells.
    American journal of physiology. Cell physiology, 2021, 07-01, Volume: 321, Issue:1

    Topics: Amiloride; Cell Line; Cell Line, Tumor; Clone Cells; Epithelial Cells; Epithelial Sodium Channel Blockers; Gene Expression; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Dynamics; Oxidative Phosphorylation; Oxygen Consumption; Phosphofructokinase-1; Pyruvic Acid; Sodium-Hydrogen Exchanger 1

2021