Page last updated: 2024-08-21

amiloride and ibuprofen

amiloride has been researched along with ibuprofen in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's2 (12.50)18.2507
2000's6 (37.50)29.6817
2010's7 (43.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Avdeef, A; Tam, KY1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lund, C; Lynagh, T; Pless, SA; Romero-Rojo, JL1
Boer, P; Dorhout Mees, EJ; Geyskes, GG; Radó, JP; Simatupang, TA; Vos, J1
Brady, HR; Brenner, BM; Gunning, ME; Otuechere, G; Zeidel, ML1
Bełtowski, J; Górny, D; Marciniak, A1
Cadiou, H; Jones, NG; McMahon, SB; McNaughton, P; Slater, R1
Hegazy, MA1

Reviews

1 review(s) available for amiloride and ibuprofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for amiloride and ibuprofen

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Molecular Basis for Allosteric Inhibition of Acid-Sensing Ion Channel 1a by Ibuprofen.
    Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19

    Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Allosteric Regulation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chick Embryo; Ibuprofen; Models, Molecular; Protein Conformation; Rats; Structure-Activity Relationship; Xenopus laevis

2017
Pharmacologic studies in Bartter's syndrome: opposite effects of treatment with antikaliuretic and antiprostaglandin drugs. Part I.
    International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:1

    Topics: Adult; Amiloride; Bartter Syndrome; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Male; Potassium; Propranolol; Prostaglandin Antagonists; Renin; Sodium; Spironolactone; Time Factors

1978
Atrial natriuretic peptide(31-67) inhibits Na+ transport in rabbit inner medullary collecting duct cells. Role of prostaglandin E2.
    The Journal of clinical investigation, 1992, Volume: 89, Issue:5

    Topics: Amiloride; Animals; Atrial Natriuretic Factor; Biological Transport; Cells, Cultured; Dinoprostone; Ibuprofen; In Vitro Techniques; Kidney Medulla; Kidney Tubules, Collecting; Natriuresis; Ouabain; Oxygen Consumption; Peptide Fragments; Rabbits; Sodium; Structure-Activity Relationship

1992
Biphasic effect of protein kinase C on rat renal cortical Na+, K+-ATPase.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:4

    Topics: Amiloride; Amphotericin B; Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; Kidney Cortex; Male; Oxazines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate

1998
Acid-induced pain and its modulation in humans.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Dec-01, Volume: 24, Issue:48

    Topics: Acid Sensing Ion Channels; Administration, Cutaneous; Adult; Amiloride; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Diclofenac; Female; Forearm; Hot Temperature; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Hyperalgesia; Ibuprofen; Injections, Subcutaneous; Ion Channels; Iontophoresis; Male; Membrane Proteins; Middle Aged; Nerve Tissue Proteins; Pain; Pain Measurement; Pain Threshold; Refractory Period, Electrophysiological; Single-Blind Method; Sodium Channels; TRPV Cation Channels

2004
A novel pure component contribution algorithm (PCCA) for extracting components' contribution from severely overlapped signals; an application to UV-spectrophotometric data.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Volume: 151

    Topics: Acetaminophen; Algorithms; Amiloride; Atenolol; Capsules; Hydrochlorothiazide; Ibuprofen; Spectrophotometry, Ultraviolet; Tablets

2015