Page last updated: 2024-08-21

amiloride and glyburide

amiloride has been researched along with glyburide in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (19.35)18.2507
2000's17 (54.84)29.6817
2010's8 (25.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Husted, RF; Sigmund, RD; Stokes, JB; Volk, KA1
Boutellier, S; Lutz, TA; Rossi, R; Scharrer, E; Seebacher, MC; Sutter, DA1
DeLano, FA; Moazzam, F; Schmid-Schönbein, GW; Zweifach, BW1
Campos, Y; Fernandez, M; Mendoza-León, A; Moll, H; Ponte-Sucre, A1
Matthay, MA; Nakada, T; Ohya, N; Sakuma, T; Takahashi, K1
Chrabi, A; Horisberger, JD1
Bridges, RJ; Devor, DC; Gerlach, AC; Gondor, M; Pilewski, JM; Singh, AK1
Kang, YY; Kim, JA; Lee, YS1
Akagawa, Y; Hirono, C; Iwasa, Y; Nakamoto, T; Shiba, Y; Sugita, M1
Grantham, JJ; Rome, LA; Sullivan, LP; Wallace, DP1
Ingbar, DH; Jiang, X; O'Grady, SM1
Bens, M; Cluzeaud, F; Duong Van Huyen, JP; Teulon, J; Vandewalle, A1
Ago, T; Ibayashi, S; Iida, M; Kamouchi, M; Kitazono, T; Ooboshi, H; Santa, N; Wakisaka, M1
Lazrak, A; Matalon, S1
Berthiaume, Y; Brochiero, E; Dagenais, A; Leroy, C1
Kontos, HA; Rosenblum, WI; Wei, EP1
Finkbeiner, WF; Muanprasat, C; Nielson, DW; Pedemonte, N; Salinas, DB; Verkman, AS1
Hanafusa, T; Ito, S; Kishima, G; Kubota, T; Marunaka, Y; Murao, H; Nakahari, T; Niisato, N; Shimamoto, C; Sugimoto, T; Tokuda, S; Yoshida, H1
Jonker, DM; Karlsson, MO; Kerbusch, T; Savic, RM1
Chraibi, A; Renauld, S1
Assa, S; Dehpour, AR; Elmi, A; Emami, H; Nezami, BG; Ostovaneh, MR; Talab, SS1
Deachapunya, C; Poonyachoti, S1
Binder, HJ; Cheng, CY; Cheng, SX; Fang, X; Rivkees, SA; Tang, L; Winesett, SP1

Reviews

2 review(s) available for amiloride and glyburide

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

29 other study(ies) available for amiloride and glyburide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Anion secretion by the inner medullary collecting duct. Evidence for involvement of the cystic fibrosis transmembrane conductance regulator.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Analysis of Variance; Animals; Anions; Base Sequence; Bicarbonates; Bumetanide; Cells, Cultured; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Primers; Epithelium; Female; Glyburide; Glycolates; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Membrane Proteins; Molecular Sequence Data; Nitrobenzoates; Ouabain; Patch-Clamp Techniques; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Rats, Wistar

1995
Hyperpolarization of hepatocytes by 2,5-AM: implications for hepatic control of food intake.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2

    Topics: Amiloride; Animals; Apamin; Appetite; Azepines; Barium; Bicarbonates; Chlorides; Female; Flufenamic Acid; Glyburide; Homeostasis; In Vitro Techniques; Liver; Male; Mannitol; Membrane Potentials; Mice; Mice, Inbred ICR; Ouabain; Potassium Channel Blockers; Potassium Channels; Quinine; Rats; Rats, Sprague-Dawley; Sodium

1997
The leukocyte response to fluid stress.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, May-13, Volume: 94, Issue:10

    Topics: Amiloride; Analysis of Variance; Animals; Calcium Channel Blockers; Cell Adhesion; Cell Membrane; Cell Movement; Choline; Glyburide; Humans; Leukocytes; Male; Microcirculation; Monocytes; Neutrophils; Ouabain; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium Channel Blockers; Splanchnic Circulation; Stress, Mechanical; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Venules

1997
Leishmania sp.: growth and survival are impaired by ion channel blockers.
    Experimental parasitology, 1998, Volume: 88, Issue:1

    Topics: 4-Aminopyridine; Amiloride; Animals; Anthracenes; Cell Line; Cells, Cultured; Glyburide; Humans; Ion Channels; Leishmania; Macrophages; Mice

1998
Effects of ATP-sensitive potassium channel opener on potassium transport and alveolar fluid clearance in the resected human lung.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:1

    Topics: Adenosine Triphosphate; Aged; Amiloride; Benzoxazines; Body Fluids; Cyclic N-Oxides; Epithelium; Extracellular Space; Glyburide; Humans; Ion Transport; Lung; Middle Aged; Oxazines; Pneumonectomy; Potassium; Potassium Channels; Pulmonary Alveoli

1998
Stimulation of epithelial sodium channel activity by the sulfonylurea glibenclamide.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1

    Topics: Amiloride; Animals; Biological Transport; Cells, Cultured; Epithelial Cells; Epithelial Sodium Channels; Glyburide; Humans; In Vitro Techniques; Oocytes; Patch-Clamp Techniques; Rats; Sodium; Sodium Channels; Stimulation, Chemical; Xenopus laevis

1999
Stimulation of Cl(-) secretion by chlorzoxazone.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2

    Topics: Amiloride; Anions; Bronchi; Bumetanide; Cell Membrane; Cells, Cultured; Charybdotoxin; Chlorine; Chlorzoxazone; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Interactions; Epithelium; Glyburide; Humans; Isoproterenol; Nasal Mucosa; Nystatin; Potassium Channel Blockers; Rubidium; Zoxazolamine

2000
Activation of Na(+), K(+), Cl(-)-cotransport mediates intracellular Ca(2+) increase and apoptosis induced by Pinacidil in HepG2 human hepatoblastoma cells.
    Biochemical and biophysical research communications, 2001, Feb-23, Volume: 281, Issue:2

    Topics: Adenosine Triphosphate; Amiloride; Apoptosis; Bepridil; Bumetanide; Calcium; Carrier Proteins; DNA Fragmentation; Dose-Response Relationship, Drug; Furosemide; Glyburide; Hepatoblastoma; Humans; Pinacidil; Potassium; Potassium Channel Blockers; Potassium Channels; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Chloride Symporters; Time Factors; Tolbutamide; Tumor Cells, Cultured

2001
Gramicidin-perforated patch analysis on HCO3- secretion through a forskolin-activated anion channel in rat parotid intralobular duct cells.
    The Journal of membrane biology, 2001, Mar-01, Volume: 180, Issue:1

    Topics: Amiloride; Animals; Anions; Bicarbonates; Bumetanide; Chlorides; Colforsin; Glyburide; Gramicidin; In Vitro Techniques; Male; Membrane Potentials; Methazolamide; Parotid Gland; Patch-Clamp Techniques; Rats; Rats, Wistar

2001
cAMP-dependent fluid secretion in rat inner medullary collecting ducts.
    American journal of physiology. Renal physiology, 2001, Volume: 280, Issue:6

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Barium; Biological Transport; Blood Proteins; Calcium Channel Blockers; Chlorides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Dissection; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Isoquinolines; Kidney Medulla; Kidney Tubules, Collecting; Male; ortho-Aminobenzoates; Ouabain; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Vanadates; Water; Water-Electrolyte Balance

2001
Adrenergic regulation of ion transport across adult alveolar epithelial cells: effects on Cl- channel activation and transport function in cultures with an apical air interface.
    The Journal of membrane biology, 2001, Jun-01, Volume: 181, Issue:3

    Topics: Adrenergic Agents; Adrenergic beta-Agonists; Air; Amiloride; Animals; Cell Membrane Permeability; Cell Polarity; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Glyburide; Immunohistochemistry; Inhibitory Concentration 50; Ion Channel Gating; Ion Transport; Male; Nitrobenzoates; Patch-Clamp Techniques; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Sodium; Terbutaline

2001
CFTR disruption impairs cAMP-dependent Cl(-) secretion in primary cultures of mouse cortical collecting ducts.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:3

    Topics: Amiloride; Animals; Cells, Cultured; Chloride Channels; Chlorides; Crosses, Genetic; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Deamino Arginine Vasopressin; Epithelial Sodium Channels; Glyburide; Homozygote; Isoproterenol; Kidney Cortex; Kidney Tubules, Collecting; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrobenzoates; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channel Blockers; Sodium Channels; Sodium Chloride; Transcription, Genetic

2001
ATP-sensitive potassium channels mediate dilatation of basilar artery in response to intracellular acidification in vivo.
    Stroke, 2003, Volume: 34, Issue:5

    Topics: Amiloride; Animals; ATP-Binding Cassette Transporters; Basilar Artery; Cells, Cultured; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Glyburide; Hydrogen-Ion Concentration; Indomethacin; Intracellular Fluid; Ion Transport; Macromolecular Substances; Male; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Organ Specificity; Pancreas; Peptides; Potassium; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Drug; Sodium-Hydrogen Exchangers; Sulfonylurea Receptors; Vasodilation

2003
cAMP-induced changes of apical membrane potentials of confluent H441 monolayers.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 285, Issue:2

    Topics: Amiloride; Cell Culture Techniques; Cell Line; Cell Membrane; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Sodium Channels; Glyburide; Humans; Kinetics; Lung; Membrane Potentials; Patch-Clamp Techniques; Respiratory Mucosa; Sodium Channels

2003
Molecular identity and function in transepithelial transport of K(ATP) channels in alveolar epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 286, Issue:5

    Topics: Amiloride; Animals; ATP-Binding Cassette Transporters; Base Sequence; Colforsin; DNA; DNA Primers; Glyburide; Kinetics; Male; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, Drug; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Sulfonylurea Receptors

2004
Vasodilation of brain surface arterioles by blockade of Na-H+ antiport and its inhibition by inhibitors of KATP channel openers.
    Brain research, 2004, Apr-16, Volume: 1005, Issue:1-2

    Topics: Amiloride; Animals; Arterioles; Brain; Dose-Response Relationship, Drug; Glyburide; Male; Pia Mater; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Vasodilation

2004
CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:5

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Benzoates; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Female; Glyburide; Hypoglycemic Agents; Male; Membrane Potentials; Mice; Mice, Inbred CFTR; Nasal Mucosa; Sus scrofa; Thiazoles; Thiazolidines

2004
HCO(-3)-dependent pHi recovery and overacidification induced by NH+4 pulse in rat lung alveolar type II cells: HCO(-3)-dependent NH3 excretion from lungs?
    Pflugers Archiv : European journal of physiology, 2007, Volume: 455, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Ammonia; Animals; Bicarbonates; Bumetanide; Carbonic Anhydrases; Chloride Channels; Enzyme Inhibitors; Glyburide; Hydrogen-Ion Concentration; Macrolides; Male; Nitrobenzoates; Pulmonary Alveoli; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters

2007
Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies.
    Journal of pharmacokinetics and pharmacodynamics, 2007, Volume: 34, Issue:5

    Topics: Absorption; Adult; Aged; Aged, 80 and over; Amiloride; Female; Furosemide; Glyburide; Humans; Imidazoles; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Pharmacokinetics

2007
Role of the C-terminal part of the extracellular domain of the alpha-ENaC in activation by sulfonylurea glibenclamide.
    The Journal of membrane biology, 2009, Volume: 230, Issue:3

    Topics: Amiloride; Amino Acid Sequence; Animals; Electrophysiology; Epithelial Sodium Channel Agonists; Epithelial Sodium Channels; Glyburide; Guinea Pigs; Humans; Hypoglycemic Agents; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Sodium Channel Blockers; Xenopus

2009
Na(+)-H+ exchange inhibition attenuates ischemic injury in rat random pattern skin flap: the role of mitochondrial ATP-sensitive potassium channels.
    European journal of pharmacology, 2013, Jan-05, Volume: 698, Issue:1-3

    Topics: Amiloride; Animals; Dermatologic Surgical Procedures; Diazoxide; Glyburide; Ion Channel Gating; Ischemia; KATP Channels; Male; Mitochondria; Postoperative Complications; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Surgical Flaps; Tissue Survival

2013
Activation of chloride secretion by isoflavone genistein in endometrial epithelial cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 32, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Bumetanide; Cell Membrane Permeability; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Endometrium; Epithelial Cells; Estradiol; Female; Fulvestrant; Genistein; Glyburide; Swine; Uridine Triphosphate

2013
Bumetanide increases Cl--dependent short-circuit current in late distal colon: Evidence for the presence of active electrogenic Cl- absorption.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Amiloride; Animals; Barium; Bumetanide; Chlorides; Colon; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Epithelium; Gene Expression Regulation; Glyburide; Male; Organ Culture Techniques; Rats, Sprague-Dawley; Sodium

2017