Page last updated: 2024-08-21

amiloride and eplerenone

amiloride has been researched along with eplerenone in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's8 (61.54)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kusano, E; Miyata, Y; Muto, S1
Griffon, C; Miternique-Grosse, A; Neuville, A; Siegel, L; Stephan, D; Weltin, D1
Gabor, A; Leenen, FH1
Stowasser, M1
Ecker, G; Masilamani, SM; West, C; Zhang, Z1
Brownstein, DG; Chapman, K; Deuchar, GA; Hadoke, PWF; Kotelevtsev, YV; McLean, D; Mullins, JJ; Seckl, JR; Webb, DJ1
Kumagai, H; Nishida, Y; Oda, T; Onimaru, H; Oshima, N; Takechi, H; Uchida, T; Watanabe, A; Yamamoto, K1
Carretero, OA; D'Ambrosio, MA; Garvin, JL; Kutskill, K; Leung, P; Peterson, EL; Ren, Y; Wang, H1
Allard, J; Azizi, M; Baron, S; Bergerot, D; Blanchard, A; Bridoux, F; Caumont-Prim, A; Desport, E; Dubourg, L; Essig, M; Monge, M; Tack, I; Vallet, M; Vargas-Poussou, R1
Chudek, J; Maruniak-Chudek, I; Olszanecka-Glinianowicz, M; Sikora, J; Wyskida, K; Wyskida, M1
Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Yeasmin, S1
Brown, JM; Heydarpour, M; Mannstadt, M; Parksook, WW; Turchin, A; Vaidya, A1

Reviews

3 review(s) available for amiloride and eplerenone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Hypertension in the course of primary aldosteronism during pregnancy].
    Postepy higieny i medycyny doswiadczalnej (Online), 2015, Feb-15, Volume: 69

    Topics: Acid Sensing Ion Channel Blockers; Aldosterone; Amiloride; Antihypertensive Agents; Eplerenone; Female; Humans; Hyperaldosteronism; Hypertension; Poland; Pregnancy; Pregnancy Complications; Progesterone; Spironolactone

2015
Dose doubling, relative potency, and dose equivalence of potassium-sparing diuretics affecting blood pressure and serum potassium: systematic review and meta-analyses.
    Journal of hypertension, 2016, Volume: 34, Issue:1

    Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Eplerenone; Humans; Hyperkalemia; Potassium; Sodium Chloride Symporter Inhibitors; Spironolactone; Therapeutic Equivalency; Triamterene

2016

Trials

2 trial(s) available for amiloride and eplerenone

ArticleYear
Indomethacin, amiloride, or eplerenone for treating hypokalemia in Gitelman syndrome.
    Journal of the American Society of Nephrology : JASN, 2015, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Amiloride; Blood Pressure; Body Weight; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Eplerenone; Female; Gitelman Syndrome; Glomerular Filtration Rate; Heart Rate; Humans; Hypokalemia; Indomethacin; Male; Middle Aged; Potassium; Renin; Spironolactone; Treatment Outcome; Young Adult

2015
Evaluating the clinical and mechanistic effects of eplerenone and amiloride monotherapy, and combination therapy with cinacalcet, in primary hyperparathyroidism: A placebo-controlled randomized trial.
    Clinical endocrinology, 2023, Volume: 98, Issue:4

    Topics: Aldosterone; Amiloride; Calcium; Cinacalcet; Eplerenone; Female; Humans; Hyperparathyroidism, Primary; Male; Parathyroid Hormone; Renin

2023

Other Studies

8 other study(ies) available for amiloride and eplerenone

ArticleYear
Mechanisms for nongenomic and genomic effects of aldosterone on Na+/H+ exchange in vascular smooth muscle cells.
    Journal of hypertension, 2005, Volume: 23, Issue:12

    Topics: Aldosterone; Amiloride; Animals; Cells, Cultured; Eplerenone; Fluorescent Dyes; Genome; Hydrogen-Ion Concentration; Ion Transport; Kinetics; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Rats; Sodium-Hydrogen Exchangers; Spironolactone

2005
Antiangiogenic effects of spironolactone and other potassium-sparing diuretics in human umbilical vein endothelial cells and in fibrin gel chambers implanted in rats.
    Journal of hypertension, 2006, Volume: 24, Issue:11

    Topics: Amiloride; Angiogenesis Inhibitors; Animals; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Eplerenone; Fibrin; Humans; Male; Neovascularization, Physiologic; Rats; Rats, Wistar; Sodium Channel Blockers; Spironolactone; Umbilical Veins

2006
Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:3

    Topics: Aldosterone; Amiloride; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cerebrospinal Fluid; Diuretics; Dose-Response Relationship, Drug; Eplerenone; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Ouabain; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Sodium; Spironolactone

2009
Update in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:10

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Amiloride; Antihypertensive Agents; Chromosomes, Human, Pair 7; Cytochrome P-450 CYP11B2; Diagnosis, Differential; Drug Administration Schedule; Eplerenone; Genetic Linkage; Glucocorticoids; Humans; Hyperaldosteronism; Hypertension; Lod Score; Mineralocorticoid Receptor Antagonists; Spironolactone

2009
Increased renal alpha-epithelial sodium channel (ENAC) protein and increased ENAC activity in normal pregnancy.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:5

    Topics: Amiloride; Animals; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Eplerenone; Female; Immunoblotting; Kidney; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Natriuresis; Plasma Volume; Pregnancy; Proteomics; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; Spironolactone; Up-Regulation

2010
11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice.
    Endocrinology, 2011, Volume: 152, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Amiloride; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Line; Endothelium, Vascular; Eplerenone; Gene Expression Regulation, Enzymologic; Inflammation; Male; Mice; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Sodium Channel Blockers; Spironolactone

2011
Aldosterone is synthesized in and activates bulbospinal neurons through mineralocorticoid receptors and ENaCs in the RVLM.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:6

    Topics: Aldosterone; Amiloride; Animals; Aromatase Inhibitors; Calcium; Diuretics; Epithelial Sodium Channels; Eplerenone; Excitatory Postsynaptic Potentials; Fadrozole; Magnesium; Medulla Oblongata; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spinal Cord; Spironolactone; Tissue Fixation

2013
Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30.
    American journal of physiology. Renal physiology, 2014, Aug-15, Volume: 307, Issue:4

    Topics: Aldosterone; Amiloride; Animals; Arterioles; Cycloheximide; Dactinomycin; Epithelial Sodium Channels; Eplerenone; Feedback; Kidney Tubules; Male; Rabbits; Receptors, G-Protein-Coupled; Receptors, Mineralocorticoid; Spironolactone

2014