amiloride has been researched along with 5-dimethylamiloride in 231 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (15.15) | 18.7374 |
| 1990's | 122 (52.81) | 18.2507 |
| 2000's | 66 (28.57) | 29.6817 |
| 2010's | 7 (3.03) | 24.3611 |
| 2020's | 1 (0.43) | 2.80 |
| Authors | Studies |
|---|---|
| Conway, SJ; Ganapathy, V; George, RL; Huang, W; Leibach, FH; Wang, H; Wu, X | 1 |
| Bilodeau, MT; Bock, MG; Cato, MJ; Chang, RK; Cook, SP; Di Marco, CN; Dipardo, RM; Hartman, GD; Jovanovska, A; Kane, SA; Kuduk, SD; Leitl, M; Spencer, RH; Urban, MO | 1 |
| Crandall, ED; Lubman, RL; Russo, RM | 1 |
| Lang, HJ; Popp, R; Schmid, A; Scholz, W | 1 |
| Gist, ID; Kiang, JG; Smallridge, RC | 1 |
| Foster, CD; Honeyman, TW; Scheid, CR | 1 |
| Häussinger, D; Lang, F; Ritter, M; Wöll, E | 1 |
| Bolard, J; Cybulska, B; Czerwinski, A; Henry-Toulme, N; Seksek, O | 1 |
| Chambers, TJ; Hall, TJ; Schaeublin, M | 1 |
| Asher, C; Dascal, N; Eren, R; Garty, H; Singer, D; Yeger, O | 1 |
| Cocks, BG; Cragoe, EJ; Hamilton, JA; Vairo, G | 1 |
| Asawa, T; Komiya, I; Nagasawa, Y; Shimizu, Y; Takasu, N; Yamada, T | 1 |
| Cragoe, EJ; Pollard, HB; Rosario, LM; Stutzin, A | 1 |
| Helmle-Kolb, C; Krapf, R; Krayer-Pawlowska, D; Montrose, MH; Murer, H | 1 |
| Lonsberry, BB; Meng, HP; Pierce, GN | 1 |
| Burns, KD; Harris, RC; Homma, T | 1 |
| Cragoe, EJ; Momma, K; Nakanishi, T; Seguchi, M; Takao, A; Tsuchiya, T | 1 |
| Allen, JC; Cragoe, EJ; Kahn, AM; Seidel, CL; Shelat, H | 1 |
| Hamm, LL; Herndon, J; Vehaskari, VM | 1 |
| Hales, CA; Honeyman, TW; Joseph, PM; Quinn, DA; Scheid, CR; Thompson, BT | 1 |
| Budreau, A; Chesney, RW; Lohstroh, P; Stejskal, E; Zelikovic, I | 1 |
| Jinnai, Y; Kume, S; Ozaki, Y; Yatomi, Y | 1 |
| Hemsworth, PD; Rasmussen, HH; Whalley, DW | 2 |
| Andersson, RG; Cragoe, EJ; Grundström, N; Karlsson, JO; Mårtensson, LG; Svensson, SP | 1 |
| Bobik, A; Little, PJ; Neylon, CB | 1 |
| Agulian, S; Capasso, G; Giebisch, G; Unwin, R | 1 |
| Imai, S; Ishibashi, T; Nakazawa, M; Shi, AY | 1 |
| Abel, KC; Bourke, JR; Brown, L; Cragoe, EJ; Manley, SW | 1 |
| Cragoe, EJ; McArdle, CA; Poch, A | 1 |
| Battistini, B; Cragoe, EJ; Filep, JG; Fournier, A; Sirois, P | 1 |
| Aronson, JK; Brearley, CJ; Jenkins, RJ | 1 |
| Morgenstern, E; Osswald, U; Rosskopf, D; Scholz, W; Siffert, W | 1 |
| Canessa, M; Morgan, K | 1 |
| Bobik, A; Cragoe, EJ; Grinpukel, S; Grooms, A; Little, PJ | 1 |
| Meng, H; Pierce, GN | 1 |
| Clemens, N; Scheid, P; Siffert, W | 1 |
| Cragoe, EJ; Lechene, CP; Schwartz, MA | 1 |
| Kakkar, VV; Krishnamurthi, S; Morgan, WA | 1 |
| Hesketh, TR; Metcalfe, JC; Moore, JP; Pennington, SR | 1 |
| Chambers, TJ; Hall, TJ | 1 |
| Cragoe, EJ; Holsey, C; Nair, CN | 1 |
| Derian, CK; Friedman, PA; Gould, RJ | 1 |
| Bosia, A; Bussolino, F; Caracciolo, D; Gallo, E; Ghigo, D; Pannocchia, A; Tamponi, G; Tarella, C; Treves, S; Turrini, F | 1 |
| Grunicke, H; Hochleitner, BW; Maly, K | 1 |
| Canessa, ML; Conlin, PR; Kim, SY; Williams, GH | 1 |
| Cingolani, HE; Koretsune, Y; Marban, E | 1 |
| Argyriou, S; Bordun, AM; Cragoe, EJ; Gonda, TJ; Hamilton, JA; Vairo, G | 1 |
| Brock, TA; Cragoe, EJ; Danthuluri, NR; Escobales, N; Longo, E | 1 |
| Anderson, SE; Cala, PM; London, RE; Murphy, E; Steenbergen, C | 1 |
| Astarie, C; David-Dufilho, M; Devynck, MA | 1 |
| Meng, HP; Pierce, GN | 1 |
| Barbry, P; Cragoe, EJ; Frelin, C; Lazdunski, M; Vigne, P | 1 |
| Dornand, J; el Moatassim, C; Mani, JC | 1 |
| Cragoe, EJ; Lake, JR; Renner, EL; Scharschmidt, BF | 1 |
| Cragoe, EJ; Harvey, RD; Rasmussen, HH; ten Eick, RE | 1 |
| Boron, WF; Boyarsky, G; Ganz, MB; Sterzel, RB | 1 |
| Bobik, A; Cragoe, EJ; Little, PJ; Weissberg, PL | 2 |
| Doppler, W; Groner, B; Grunicke, HH; Loferer, H; Maly, K; Oberhuber, H; Uberall, F | 1 |
| Amiel, C; Bernard, C; Ferrary, E; Oudar, O; Sterkers, O | 1 |
| Banga, HS; Feinstein, MB; Halenda, SP; Lau, LF; Zavoico, GB | 1 |
| Cragoe, EJ; Gesek, FA; Strandhoy, JW | 1 |
| Beeker, TG; Muallem, S; Pandol, SJ | 1 |
| Bonanno, JA; Cragoe, EJ; Klyce, SD | 1 |
| Balkovetz, DF; Ganapathy, V; Leibach, FH; Mahesh, VB; Miyamoto, Y; Tiruppathi, C | 1 |
| Balkovetz, DF; Ganapathy, V; Hanano, M; Iwatsubo, T; Leibach, FH; Miyamoto, Y | 1 |
| Costa-Casnellie, MR; Lichtman, MA; Segel, GB | 1 |
| Fredette, JP; Griffin, JD; Horne, JH; Lazzari, KG; Leavitt, JL; Lyman, CA; Melnick, DA; Simons, ER; Sullivan, R; Wright, J | 1 |
| Bobik, A; Grinpukel, S; Grooms, A; Little, PJ | 1 |
| Aalkjaer, C; Cragoe, EJ | 1 |
| Besterman, JM; Cragoe, EJ; Cuatrecasas, P; LeVine, H; May, WS | 1 |
| Frelin, C; Lazdunski, M; Vigne, P | 1 |
| Bastie, MJ; Creach, Y; Dufresne, M; Hollande, E; Ribet, A; Vaysse, N | 1 |
| Cantley, LC; Rosoff, PM | 1 |
| Frelin, C; Green, RD; Lazdunski, M; Vigne, P | 1 |
| Cragoe, EJ; Feinstein, MB; Zavoico, GB | 1 |
| Balkovetz, DF; Cragoe, EJ; Devoe, LD; Ganapathy, V; Leibach, FH; Mahesh, VB | 1 |
| Costa-Casnellie, MR; Cragoe, EJ; Lichtman, MA; Segel, GB | 1 |
| Adelberg, EA; Agarwal, N; Amsler, K; Haggerty, JG; Slayman, CW | 1 |
| Escobales, N; Rivera, A | 1 |
| Cragoe, EJ; Ehrenfeld, J; Harvey, BJ | 1 |
| Blissard, D; Cragoe, EJ; Muallem, S; Sachs, G | 1 |
| Doppler, W; Grunicke, HH; Hofmann, J; Maly, K | 1 |
| Doppler, W; Grunicke, H; Hofmann, J; Maly, K | 1 |
| Besterman, JM; Cragoe, EJ; Cuatrecasas, P; Tyrey, SJ | 1 |
| Li, JH; Lindemann, B | 1 |
| Khimenko, PL; Moore, TM; Taylor, AE | 1 |
| Loh, TT; Zhu, WH | 1 |
| Bonventre, JV; Hales, CA; Kinane, TB; Quinn, DA; Silverman, ES; Thompson, BT | 1 |
| Crane, FL; Lawrence, J; MacKellar, WC; Morré, DJ; Morré, DM; Sun, E; Sun, I | 1 |
| Curry, M; Martinez, JR; Seagrave, JC | 1 |
| Azimi, S; Hamdani, S; Laborde, K; Sachs, C; Shahedi, M | 1 |
| Czarnowska, E; Karwatowska-Prokopczuk, E; Prokopczuk, A | 1 |
| Cagliero, E; Canessa, M; Doria, A; Lorenzi, M; Podestá, F; Roth, T; Zerbini, G | 1 |
| Bernardo, J; Brunkhorst, BA; Seetoo, KF; Simons, ER; Strohmeier, GR; Weil, GJ | 1 |
| Chao, DC; Crandall, ED; Lubman, RL | 1 |
| Doi, Y; Marunaka, Y | 1 |
| Cascio, WE; Gilliam, DE; Kaplan, SH; Lemasters, JJ; Shen, J; Yang, H | 1 |
| Abe, K; Fujiwara, I; Igarashi, Y; Ito, O; Kondo, Y; Takahashi, N | 1 |
| Delamere, NA; Dong, J | 1 |
| Lapadula, M; Storelli, C; Verri, T; Vilella, S; Zonno, V | 1 |
| Saab, EM; Vender, RL | 1 |
| Crandall, ED; Lubman, RL | 1 |
| Bizal, GL; Bookstein, C; Chang, EB; Hattabaugh, YJ; Howard, RL; McAteer, JA; Musch, MW; Rao, MC; Soleimani, M; Villereal, M | 1 |
| Counillon, L; Lang, HJ; Pouysségur, J; Scholz, W | 1 |
| Bond, JM; Chacon, E; Herman, B; Lemasters, JJ | 1 |
| Cragoe, EJ; Maidorn, RP; Tannock, IF | 1 |
| Canessa, ML; Cirillo, M; Conlin, PR; Williams, GH; Zerbini, G | 1 |
| Curry, MS; Edwards, BS; Hoffman, RR | 1 |
| Hamilton, JA; Vairo, G | 1 |
| Betz, AL; Ennis, SR; Ren, XD | 1 |
| Bonventre, JP; Dahlberg, CG; Hales, CA; Honeyman, T; Joseph, PM; Quinn, DA; Scheid, CR; Thompson, BT | 1 |
| Ho, MM; Ingrosso, L; Marsigliante, S; Muscella, A; Storelli, C; Vilella, S; Vinson, GP; Zonno, V | 1 |
| Elnageh, N; Harrington, MG | 1 |
| Azoui, R; Cuche, JL; Dagher, G; Renaud, JF; Safar, M | 1 |
| Chander, A; Spitzer, A; Wadsworth, S; Wu, AM | 1 |
| Cragoe, EJ; Filonzi, EL; Hamilton, JA; Novak, U; Royston, AK; Vadiveloo, PK; Vairo, G; Whitty, G | 1 |
| Avkiran, M; Hearse, DJ; Shimada, Y | 1 |
| Abe, T; Akita, T; Hotta, Y; Kodama, I; Koike, A; Murase, M; Takeya, K; Toyama, J | 1 |
| Clanachan, AS; Liu, B; Lopaschuk, GD; Schulz, R | 1 |
| Csar, XF; Hamilton, JA; Hoffmann, BW; Ward, AC | 1 |
| Jo, D; Thomas, AG; Vornov, JJ | 1 |
| Fukuta, M; Iwa, T; Kobayashi, T; Uesugi, M; Wakida, Y | 1 |
| Mountian, I; Van Driessche, W | 1 |
| Arai, T; Araki, T; Arbab, AS; Koizumi, K; Toyama, K | 3 |
| Doohan, MM; Gray, DF; Hool, LC; Rasmussen, HH; Robinson, BG | 1 |
| Davies, SE; Gotoh, M; Obrenovitch, TP | 1 |
| Inagaki, N; Kitai, H; Kuji, N; Nakatogawa, N; Nozawa, S; Suzuki, S | 1 |
| Ayajiki, K; Okamura, T; Toda, N | 1 |
| Hata, K; Kloner, RA; Przyklenk, K | 1 |
| Cox, T | 1 |
| Maddaford, TG; Pierce, GN | 1 |
| Cross, HR; Gabel, SA; London, RE; Murphy, E; Steenbergen, C | 1 |
| Delamere, NA; Hou, Y; Pierce, WM | 1 |
| Contreras, RJ; Lundy, RF; Pittman, DW | 1 |
| Christ, MJ; de Silva, A; Iwamoto, LM; Lavallee, SL; Nakamura, KT | 1 |
| Abete, P; Bianco, S; Cacciatore, F; Calabrese, C; Ferrara, N; Ferrara, P; Napoli, C; Rengo, F | 1 |
| Ingrosso, L; Storelli, C; Verri, T; Vilella, S; Zonno, V | 1 |
| Fukuta, Y; Hori, T; Houchi, H; Itoh, K; Katoh, I; Kitagawa, T; Tamaki, T; Yoshizumi, M | 1 |
| Cook, DI; Dinudom, A; Komwatana, P; Young, JA | 1 |
| Du, HK; Hales, CA; Quinn, DA; Thompson, BT | 1 |
| Mangili, R; Pozza, G; Zerbini, G | 1 |
| Casavola, V; Di Sole, F; Guerra, L; Perlino, E; Reshkin, SJ; Ronco, PM; Valenti, G | 1 |
| Fitzgerald, RC; Omary, MB; Triadafilopoulos, G | 1 |
| Reinach, PS; Torres-zamorano, V; Wu, X; Yang, H | 1 |
| Gewirtz, AT; Seetoo, KF; Simons, ER | 1 |
| Bookstein, C; Chang, EB; McSwine, RL; Musch, MW; Rao, M; Xie, Y | 1 |
| Ballard, ST; Gatzy, JT; Trout, L | 1 |
| Maestroni, A; Mangili, R; Pozza, G; Zerbini, G | 1 |
| Akiba, Y; Kaunitz, JD | 1 |
| Chiu, HM; Lin, HH; Tang, MJ | 1 |
| Betz, AL; Ennis, SR; Keep, RF; Shakui, P; Si, X | 1 |
| Abiko, Y; Arakawa, J; Hara, A; Hashizume, H; Ushikubi, F; Xiao, CY | 1 |
| Arakawa, J; Hara, A | 1 |
| Kocisová, E; Mirossay, A; Mirossay, L; Miskovský, P; Mojzis, J; Radváková, I | 1 |
| Albarani, V; Bellizzi, A; Casavola, V; Guerra, L; Paradiso, A; Reshkin, SJ; Tommasino, M | 1 |
| Barrigon, S; Gil-Loyzaga, P; Salinas, P | 1 |
| O'Brien, PJ; Pourahmad, J | 1 |
| Bachmann, O; Gregor, M; Mack, A; Rossmann, H; Seidler, U; Siegel, WK; Sonnentag, T; Wagner, HJ | 1 |
| Bock, C; Pörtner, HO; Reipschläger, A | 1 |
| Bonnet, U; Leniger, T; Wiemann, M | 1 |
| Khoury, J; Langleben, D | 1 |
| Benos, DJ; Benveniste, EN; Bubien, JK; Patton, HK; Zhou, ZH | 1 |
| Conway, SJ; Ganapathy, ME; Ganapathy, V; Huang, W; Kekuda, R; Leibach, FH; Wang, H; Wu, X | 1 |
| Hurtado, C; Pierce, GN | 1 |
| Albarani, V; Alunni-Fabbroni, M; Bellizzi, A; Caldeira, S; Casavola, V; Malanchi, I; Poignee, M; Reshkin, SJ; Tommasino, M | 1 |
| Choi, HS; Eisner, DA; Orchard, CH; Trafford, AW | 1 |
| Kajiwara, H; Takasaki, A; Takeo, S; Tanonaka, K | 1 |
| Keller, PA; Kleinman, JG; Madden, JA; Ray, DE | 1 |
| Descroix-Vagne, M; Grishina, O; Pansu, D; Volant, K | 1 |
| Inagaki, K; Kihara, Y; Sasayama, S; Takeuchi, Y; Yoneda, T | 1 |
| Akagawa, Y; Hirono, C; Iwasa, Y; Nakamoto, T; Shiba, Y; Sugita, M | 1 |
| Jiang, L; Li, YY; Liang, NC; Lin, XY; Wu, T | 1 |
| Akiba, Y; Engel, E; Furukawa, O; Guth, PH; Kaunitz, JD; Nastaskin, I | 1 |
| Hattori, R; Imamura, H; Matsubara, H; Moriguchi, Y; Nakao, Y; Omiya, H; Osako, M; Otani, H; Yamamura, T | 1 |
| Deitch, EA; Haskó, G; Mabley, JG; Németh, ZH; Szabó, C | 1 |
| Baron, O; Rebeyka, IM; Saiki, Y | 1 |
| Carr, MJ; Gover, TD; Undem, BJ; Weinreich, D | 1 |
| Mirossay, A; Mirossay, L; Mojzis, J; Radváková, I | 1 |
| Digerness, SB; Goldberg, SP; Holman, WL; Katholi, CR; Killingsworth, CR; Skinner, JL | 1 |
| Gaston, JS; Matyszak, MK; Young, JL | 1 |
| Burvall, K; Larsson, K; Palmberg, L | 1 |
| Avila, MY; Civan, MM; Seidler, RW; Stone, RA | 1 |
| Cox, GB; Ewart, GD; Gage, PW; Mills, K | 1 |
| Chen, HZ; Cui, XL; Wu, BW; Wu, DM | 1 |
| Delamere, NA; Hou, Y | 1 |
| Ballard, ST; Inglis, SK; Mehta, A; Trout, L | 1 |
| Murashita, T; Yasuda, K | 1 |
| Bailey, E; Gibbs, DM; Robinson, JH; von Delwig, A | 1 |
| Avila, MY; Civan, MM; Mitchell, CH; Stone, RA | 1 |
| Adamson, TP; Begay, RS; Hempleman, SC; Solomon, IC | 1 |
| Cannizzaro, C; Martire, M; Monastero, R; Vacca, M | 1 |
| Carretero, OA; Garvin, JL; Wang, H | 1 |
| Inglis, SK; Olver, RE; Wilson, SM | 1 |
| Bell, SP; Chen, Z; LeWinter, MM; Noguchi, T; Nyland, L | 1 |
| Cox, GB; Cunningham, AL; Ewart, GD; Gage, PW; Naif, H; Nasr, N | 1 |
| Furlow, JD; Waddell, DS; Weidner, WJ | 1 |
| Akiba, Y; Engel, E; Guth, PH; Kaunitz, JD; Lee, P; Lim, S; Meyerowitz, J; Mizumori, M; Supuran, CT; Takeuchi, T | 1 |
| Fernández, MA; García, JV; Marina Prendes, MG; Perazzo, JC; Savino, EA; Testoni, G; Varela, A | 1 |
| Chang, C; Chen, XH; Kong, PY; Liang, X; Liu, H; Liu, L; Peng, XG; Wang, QY; Zeng, DF | 1 |
| Akiba, Y; Engel, E; Ghayouri, S; Guth, PH; Kaunitz, JD; Mizumori, M; Swenson, ER; Takeuchi, T | 1 |
| Bachmann, O; Heinzmann, A; Mack, A; Manns, MP; Seidler, U | 1 |
| Gupta, S; Knowlton, AA | 1 |
| Aguirre, N; Di Palma, R; Goñi-Allo, B; Hervias, I; Lasheras, B; Puerta, E; Ramos, M | 1 |
| Chang, CP; Chien, EJ; Hsieh, DJ; Hsu, MT; Liao, CF; Lu, LM; Pu, HF; Shie, MC | 1 |
| Civan, MM; Macknight, AD; McLaughlin, CW; Zellhuber-McMillan, S | 1 |
| Fernández, MA; González, M; Perazzo, JC; Prendes, MG; Savino, EA; Torresín, E; Varela, A | 1 |
| Fujiki, S; Kawakami, Y; Kawanishi, T; Moriwaki, R; Namekata, I; Shigenobu, K; Takahara, A; Takeda, K; Tanaka, H | 1 |
| Akiba, Y; Engel, E; Guth, PH; Ham, M; Kaunitz, JD; Mizumori, M; Takeuchi, T | 1 |
| Gunawardana, SC; Head, WS; Piston, DW | 1 |
| Delamere, NA; Mandal, A; Shahidullah, M | 1 |
| Foskett, JK; Harlow, JM; Lee, RJ; Limberis, MP; Wilson, JM | 1 |
| Ananth, S; Ganapathy, V; Hooks, JJ; Karunakaran, S; Martin, PM; Nagineni, CN; Prasad, PD; Smith, SB | 1 |
| Candia, OA; Law, CS; To, CH | 1 |
| Arreola, J; Kaba, NK; Kim, M; Knauf, PA; Law, FY; Lefort, CT; Martel-Gallegos, G; Schultz, J; Waugh, RE | 1 |
| Arvans, DL; Chang, EB; Musch, MW; Wu, GD | 1 |
| Ambriz-Tututi, M; Araiza-Saldaña, CI; Caram-Salas, NL; Castañeda-Corral, G; Granados-Soto, V; Murbartián, J; Rocha-González, HI; Torres-López, JE | 1 |
| Soliman, M | 1 |
| Delamere, NA; Mandal, A; Shahidullah, M; Terán, MA | 1 |
| Aihara, E; Ohashi, Y; Okuda, S; Sasaki, Y; Takahashi, K; Takasuka, H; Takeuchi, K | 1 |
| Chang, CP; Chien, CH; Chien, EJ; Huang, MI; Huang, ZL; Lu, LM; Tarng, DC; Wang, OY; Wang, SW | 1 |
| Bucchieri, F; Burgio, G; Campanella, C; Cappello, F; Conway de Macario, E; Corona, DF; David, S; Macario, AJ; Marcianò, V; Merendino, AM; Ribbene, A; Zummo, G | 1 |
| Castañeda-Corral, G; Godínez-Chaparro, B; Granados-Soto, V; Jiménez-Andrade, JM; Rocha-González, HI | 1 |
| Matsuzaki, T; Okamoto, H; Sasahara, T; Tsutsui, M; Yayama, K | 1 |
| Behan, AT; Breen, B; Coughlan, K; Hogg, M; Mitchem, M; Prehn, JH; Woods, I | 1 |
| Chen, CJ; Fichna, J; Gu, Y; Hao, CM; Lai, LY; Li, K; Li, M; Li, YY; Lin, SY; Liu, SJ; Peng, A; Su, W; Zhang, MM | 1 |
| Abdullah, LH; Ballard, ST; Coakley, RD; Davis, CW; Evans, JR; Ford, AA; Griffith, JD; Kesimer, M; Makhov, AM; Nguyen, K; Wang, TT | 1 |
| Bonet, S; Maside, C; Pinart, E; Recuero, S; Salas-Huetos, A; Yeste, M | 1 |
1 review(s) available for amiloride and 5-dimethylamiloride
| Article | Year |
|---|---|
Ionic mechanisms regulating sodium entry into vascular smooth muscle.
Topics: Amiloride; Animals; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Hypertension; Ion Exchange; Muscle, Smooth, Vascular; Sodium | 1991 |
230 other study(ies) available for amiloride and 5-dimethylamiloride
| Article | Year |
|---|---|
Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carnitine; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Proteins; Structure-Activity Relationship; Symporters; Tetraethylammonium; Tissue Distribution | 2000 |
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3).
Topics: Acid Sensing Ion Channels; Acidosis; Amiloride; Amines; Animals; Chemistry, Pharmaceutical; Drug Design; Electrophysiology; Inhibitory Concentration 50; Male; Models, Chemical; Nerve Tissue Proteins; Pain; Pyrazines; Rats; Rats, Sprague-Dawley; Sodium Channels | 2009 |
Evidence for amiloride-sensitive sodium channels in alveolar epithelial cells.
Topics: Acids; Amiloride; Animals; Epithelial Cells; Epithelium; Glucose; Intracellular Membranes; Ouabain; Pulmonary Alveoli; Sodium; Sodium Channels | 1992 |
Na+/H+ exchange in porcine cerebral capillary endothelial cells is inhibited by a benzoylguanidine derivative.
Topics: Amiloride; Animals; Capillaries; Carrier Proteins; Cells, Cultured; Cerebrovascular Circulation; Endothelium, Vascular; Fluoresceins; Fluorescent Dyes; Guanidines; Hydrogen-Ion Concentration; Kinetics; Sodium; Sodium-Hydrogen Exchangers; Sulfones; Swine | 1992 |
Na+-H+ antiport and monensin effects on cytosolic pH and iodide transport in FRTL-5 rat thyroid cells.
Topics: Amiloride; Ammonium Chloride; Animals; Carrier Proteins; Cell Line; Cytosol; Hydrogen-Ion Concentration; Iodides; Kinetics; Monensin; Ouabain; Rats; Sodium; Sodium-Hydrogen Exchangers; Thyroid Gland | 1992 |
Alterations in Na(+)-H+ exchange in mesenteric arteries from spontaneously hypertensive rats.
Topics: Amiloride; Animals; Blood Pressure; Buffers; Carrier Proteins; Extracellular Space; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Mesenteric Arteries; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1992 |
Effects of bradykinin on cell volume and intracellular pH in NIH 3T3 fibroblasts expressing the ras oncogene.
Topics: 3T3 Cells; Amiloride; Animals; Bradykinin; Carrier Proteins; Fluoresceins; Gene Expression; Genes, ras; Hydrogen-Ion Concentration; Ion Channel Gating; Mice; Potassium Channels; Sodium-Hydrogen Exchangers; Transfection | 1992 |
Polyene macrolide antibiotics: indirect stimulation of the Na+/H+ exchanger of BALB/c B lymphoid cell line, A20.
Topics: Amiloride; Animals; Anti-Bacterial Agents; B-Lymphocytes; Candicidin; Carrier Proteins; Cell Division; Dose-Response Relationship, Drug; Fluoresceins; Fluorescence; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Polyenes; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1992 |
Na+/H(+)-antiporter activity is essential for the induction, but not the maintenance of osteoclastic bone resorption and cytoplasmic spreading.
Topics: Amiloride; Animals; Animals, Newborn; Anti-Bacterial Agents; Antifungal Agents; Bone Resorption; Carrier Proteins; In Vitro Techniques; Macrolides; Osteoclasts; Rats; Sodium-Hydrogen Exchangers; Time Factors | 1992 |
NaCl-dependent expression of amiloride-blockable Na+ channel in Xenopus oocytes.
Topics: Amiloride; Animals; Cell Membrane Permeability; Chickens; Diet, Sodium-Restricted; Electrophysiology; Female; Intestinal Mucosa; Microinjections; Oocytes; RNA; Sodium; Sodium Channels; Sodium Chloride; Xenopus laevis | 1992 |
Selective suppression of growth factor-induced cell cycle gene expression by Na+/H+ antiport inhibitors.
Topics: Amiloride; Animals; Carrier Proteins; Cell Cycle; Cells, Cultured; Cyclins; DNA; DNA Replication; Gene Expression; In Vitro Techniques; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Mice, Inbred Strains; Nuclear Proteins; Proliferating Cell Nuclear Antigen; RNA; RNA, Messenger; Sodium-Hydrogen Exchangers | 1992 |
Interrelationship between insulin-like growth factor I-induced activation of the Na+/H(+)-antiporter and intracellular Ca(2+)-mobilization in thyroid cells.
Topics: Amiloride; Animals; Calcium; Carrier Proteins; Cells, Cultured; Cytoplasm; Fluoresceins; Fluorescent Dyes; Fura-2; Hydrogen-Ion Concentration; Insulin-Like Growth Factor I; Kinetics; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Swine; Thyroid Gland | 1991 |
Modulation of intracellular pH by secretagogues and the Na+/H+ antiporter in cultured bovine chromaffin cells.
Topics: Adrenal Medulla; Amiloride; Animals; Calcium; Calcium Channel Blockers; Carrier Proteins; Cattle; Cells, Cultured; Epinephrine; Fluoresceins; Hydrogen-Ion Concentration; Intracellular Fluid; Parasympathomimetics; Potassium; Secretory Rate; Sodium-Hydrogen Exchangers | 1991 |
Studies on the kinetics of Na+/H+ exchange in OK cells: introduction of a new device for the analysis of polarized transport in cultured epithelia.
Topics: Amiloride; Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Epithelium; Fluoresceins; Hydrogen-Ion Concentration; Ion Exchange; Kidney; Kinetics; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Influence of perfusate pH on the postischemic recovery of cardiac contractile function: involvement of sodium-hydrogen exchange.
Topics: Amiloride; Animals; Carrier Proteins; Creatine Kinase; Heart Ventricles; Hydrogen-Ion Concentration; Male; Myocardial Contraction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers; Ventricular Function; Ventricular Function, Right | 1991 |
Regulation of Na(+)-H+ exchange by ATP depletion and calmodulin antagonism in renal epithelial cells.
Topics: Adenosine Triphosphate; Amiloride; Animals; Calmodulin; Carrier Proteins; Cell Membrane; Cells, Cultured; Cytosol; Epithelial Cells; Epithelium; Hydrogen-Ion Concentration; Kidney; Protein Kinase C; Sodium-Hydrogen Exchangers; Sulfonamides | 1991 |
Effect of partial Na pump and Na-H exchange inhibition on [Ca]i during acidosis in cardiac cells.
Topics: Acidosis; Amiloride; Animals; Calcium; Carrier Proteins; Cell Separation; Hydrogen-Ion Concentration; Myocardial Contraction; Myocardium; Osmolar Concentration; Ouabain; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1991 |
Effects of pHi on Na(+)-H+, Na(+)-dependent, and Na(+)-independent C1(-)-HCO3-exchangers in vascular smooth muscle.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Carrier Proteins; Cells, Cultured; Chloride-Bicarbonate Antiporters; Dogs; Female; Fluoresceins; Hydrogen-Ion Concentration; Male; Muscle, Smooth, Vascular; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Mechanism of sodium transport inhibition by epidermal growth factor in cortical collecting ducts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport, Active; Calcium; Carrier Proteins; Desoxycorticosterone; Epidermal Growth Factor; Indomethacin; Isoquinolines; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Piperazines; Protein Kinase C; Rabbits; Reference Values; Sodium; Sodium-Hydrogen Exchangers; Virulence Factors, Bordetella | 1991 |
Contribution of Na+/H+ exchange to pH regulation in pulmonary artery smooth muscle cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bicarbonates; Carrier Proteins; Cells, Cultured; Fluoresceins; Guinea Pigs; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Developmental maturation of Na(+)-H+ exchange in rat renal tubular brush-border membrane.
Topics: Aging; Amiloride; Animals; Biological Transport; Carrier Proteins; Hydrogen-Ion Concentration; Kidney Tubules; Kinetics; Microvilli; Protons; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Role of sodium ion gradient in facilitating extracellular calcium influx.
Topics: Amiloride; Aniline Compounds; Calcium; Carrier Proteins; Flow Cytometry; Fluorescent Dyes; Fura-2; Humans; Platelet Activation; Sodium; Sodium-Hydrogen Exchangers; Thrombin; Xanthenes | 1991 |
Sodium-hydrogen exchange in guinea-pig ventricular muscle during exposure to hyperosmolar solutions.
Topics: Acidosis; Alkalosis; Amiloride; Animals; Guinea Pigs; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange; Microelectrodes; Muscles; Osmolar Concentration; Protons; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Solutions; Ventricular Function | 1991 |
Antagonistic effect of amiloride on alpha-2 adrenoceptor-mediated pigment aggregation: pharmacological heterogeneity between B-HT 920 and noradrenaline.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Azepines; Cyclic AMP; Fishes; Norepinephrine; Pigments, Biological; Receptors, Adrenergic, alpha; Sodium | 1991 |
Bicarbonate transport along the loop of Henle. I. Microperfusion studies of load and inhibitor sensitivity.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Absorption; Acid-Base Equilibrium; Amiloride; Animals; Anti-Bacterial Agents; Bicarbonates; Biological Transport; Bumetanide; Furosemide; Loop of Henle; Macrolides; Male; Methazolamide; Nitrobenzoates; Perfusion; Permeability; Rats; Rats, Inbred Strains | 1991 |
Na+/H+ exchange is not operative under low-flow ischemic conditions.
Topics: Amiloride; Ammonium Chloride; Animals; Blood Pressure; Coronary Disease; Energy Metabolism; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange; Magnetic Resonance Spectroscopy; Male; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Inbred Strains; Sodium | 1991 |
Amiloride analogues induce responses in isolated rat cardiovascular tissues by inhibition of Na+/Ca2+ exchange.
Topics: Amiloride; Animals; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Heart Rate; In Vitro Techniques; Myocardial Contraction; Rats; Sodium; Vasodilation | 1991 |
Na+ dependence of gonadotropin-releasing hormone action: characterization of the Na+/H+ antiport in pituitary gonadotropes.
Topics: Amiloride; Animals; Basophils; Bicarbonates; Buserelin; Calcimycin; Carrier Proteins; Female; Gonadotropin-Releasing Hormone; Gonadotropins; Luteinizing Hormone; Pituitary Gland, Anterior; Rats; Sodium; Sodium-Hydrogen Exchangers | 1991 |
A role for Na+/H+ exchange in contraction of guinea pig airways by endothelin-1 in vitro.
Topics: Amiloride; Animals; Biological Transport; Bronchoconstriction; Carrier Proteins; Dose-Response Relationship, Drug; Endothelins; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Increases in Na/K pump numbers in isolated human lymphocytes exposed to lithium in vitro. Reversal by myo-inositol and by inhibitors of protein kinase C and the Na/H antiport.
Topics: Adult; Alkaloids; Amiloride; Carrier Proteins; Female; Humans; Inositol; Lithium; Lymphocytes; Male; Ouabain; Potassium; Protein Kinase C; Rubidium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Staurosporine | 1991 |
Rapid determination of the elevated Na(+)-H+ exchange in platelets of patients with essential hypertension using an optical swelling assay.
Topics: Adult; Amiloride; Blood Platelets; Carrier Proteins; Female; Humans; Hypertension; Male; Microscopy, Electron; Optics and Photonics; Osmosis; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Interactions of external and internal H+ and Na+ with Na+/Na+ and Na+/H+ exchange of rabbit red cells: evidence for a common pathway.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Biological Transport; Carrier Proteins; Erythrocytes; Hydrogen-Ion Concentration; Kinetics; Male; Protons; Rabbits; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Ethylisopropylamiloride-sensitive pH control mechanisms modulate vascular smooth muscle cell growth.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Aorta; Blood; Cattle; Cell Division; Cells, Cultured; Culture Media; DNA Replication; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1991 |
Involvement of sodium in the protective effect of 5-(N,N-dimethyl)-amiloride on ischemia-reperfusion injury in isolated rat ventricular wall.
Topics: Amiloride; Animals; Coronary Disease; Heart; Heart Ventricles; Male; Myocardial Reperfusion Injury; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium; Spectrophotometry, Atomic | 1991 |
Thrombin-induced cytosolic alkalinization in human platelets occurs without an apparent involvement of HCO3-/Cl- exchange.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Bicarbonates; Blood Platelets; Bumetanide; Cytosol; Humans; Hydrogen-Ion Concentration; Kinetics; Thrombin | 1990 |
pH regulation in spread cells and round cells.
Topics: Amiloride; Bicarbonates; Carrier Proteins; Cell Adhesion; Cell Physiological Phenomena; Cells; Chlorides; Hydrogen-Ion Concentration; Sodium-Hydrogen Exchangers | 1990 |
Extracellular Na+, but not Na+/H+ exchange, is necessary for receptor-mediated arachidonate release in platelets.
Topics: Adenosine Diphosphate; Amiloride; Arachidonic Acids; Blood Platelets; Carrier Proteins; Humans; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Ionomycin; Sodium; Sodium-Hydrogen Exchangers; Thrombin | 1990 |
Mitogen-stimulated activation of the Na+/H+ antiporter does not regulate S6 phosphorylation or protein synthesis in murine thymocytes or Swiss 3T3 fibroblasts.
Topics: Amiloride; Animals; Carrier Proteins; Cell Cycle; Cells, Cultured; DNA Replication; Fibroblasts; Growth Substances; Hydrogen-Ion Concentration; Lymphocyte Activation; Mice; Mitogens; Phosphorylation; Protein Biosynthesis; Protein Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Ribosomal Protein S6 Kinases; Ribosomal Proteins; Sodium-Hydrogen Exchangers; T-Lymphocytes | 1990 |
Na+/H+ antiporter is the primary proton transport system used by osteoclasts during bone resorption.
Topics: Adenosine Triphosphatases; Amiloride; Animals; Animals, Newborn; Biological Transport; Bone Resorption; Carrier Proteins; H(+)-K(+)-Exchanging ATPase; Omeprazole; Osteoclasts; Protons; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers | 1990 |
Evidence for poliovirus-induced cytoplasmic alkalinization in HeLa cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Biological Transport; Carrier Proteins; Cytoplasm; Dimethadione; HeLa Cells; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Nigericin; Poliovirus; Sodium-Hydrogen Exchangers; Virus Replication | 1990 |
Proaggregatory effect of epinephrine on rabbit platelets inhibited by ticlopidine.
Topics: Adenosine Diphosphate; Amiloride; Animals; Aspirin; Drug Interactions; Epinephrine; Hydrogen-Ion Concentration; Male; Methylamines; Monensin; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Receptors, Adrenergic, alpha; Sodium; Thromboxane A2; Ticlopidine | 1990 |
Role of Na+/H+ exchange in the granulocyte-macrophage colony-stimulating factor-dependent growth of a leukemic cell line.
Topics: Amiloride; Carrier Proteins; Cell Division; Cell Survival; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Hydrogen-Ion Concentration; Leukemia, Monocytic, Acute; Monensin; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1990 |
Interrelationship between growth factor-induced activation of the Na+/H(+)-antiporter and mobilization of intracellular Ca2+ in NIH3T3-fibroblasts.
Topics: Amiloride; Animals; Bombesin; Calcium; Carrier Proteins; Cells, Cultured; Cytosol; Fibroblasts; Growth Substances; Hydrogen-Ion Concentration; Kinetics; Mice; Sodium-Hydrogen Exchangers | 1990 |
Na(+)-H+ exchanger kinetics in adrenal glomerulosa cells and its activation by angiotensin II.
Topics: Aldosterone; Amiloride; Angiotensin II; Animals; Carrier Proteins; Cattle; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchangers; Zona Glomerulosa | 1990 |
Recovery of contractility and pHi during respiratory acidosis in ferret hearts: role of Na(+)-H+ exchange.
Topics: Acidosis, Respiratory; Amiloride; Animals; Carrier Proteins; Ferrets; Hydrogen; Hydrogen-Ion Concentration; Hypercapnia; Intracellular Membranes; Male; Myocardial Contraction; Myocardium; Sodium-Hydrogen Exchangers | 1990 |
Na+/H+ exchange involvement in colony-stimulating factor-1-stimulated macrophage proliferation. Evidence for a requirement during late G1 of the cell cycle but not for early growth factor responses.
Topics: Amiloride; Animals; Bone Marrow Cells; Carrier Proteins; Cells, Cultured; DNA Replication; Female; G1 Phase; Hydrogen-Ion Concentration; Kinetics; Lithium; Macrophage Activation; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Inbred CBA; Potassium; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1990 |
Osmotic activation of Na(+)-H+ exchange in human endothelial cells.
Topics: Amiloride; Carrier Proteins; Cells, Cultured; Endothelium, Vascular; Humans; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Na-H exchange in myocardium: effects of hypoxia and acidification on Na and Ca.
Topics: Amiloride; Animals; Calcium; Carrier Proteins; Heart; Hydrogen-Ion Concentration; Hypoxia; Kinetics; Magnetic Resonance Spectroscopy; Myocardium; Rabbits; Reference Values; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Direct characterization of the Na+/H+ exchanger in human platelets.
Topics: Amiloride; Blood Platelets; Carrier Proteins; Fluoresceins; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Nigericin; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Protective effects of 5-(N,N-dimethyl)amiloride on ischemia-reperfusion injury in hearts.
Topics: Amiloride; Animals; Coronary Disease; Creatine Kinase; Heart; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred Strains | 1990 |
[3H]phenamil, a radiolabelled diuretic for the analysis of the amiloride-sensitive Na+ channels in kidney membranes.
Topics: Amiloride; Animals; Binding Sites; Dose-Response Relationship, Drug; Epithelium; In Vitro Techniques; Ion Channels; Kidney; Sodium; Swine; Tritium | 1986 |
Amiloride-induced suppression of lymphocyte proliferation: inhibition of IL 2 receptor expression after blockade of early sodium influx.
Topics: Amiloride; Humans; Ion Channels; Lymphocyte Activation; Phytohemagglutinins; Potassium; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes | 1987 |
Amiloride and amiloride analogs inhibit Na+/K+-transporting ATPase and Na+-coupled alanine transport in rat hepatocytes.
Topics: Adenosine Triphosphate; Alanine; Amiloride; Animals; Biological Transport; Cell Membrane; Cells, Cultured; Ion Channels; Liver; Male; Ouabain; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Sodium; Sodium Radioisotopes; Sodium-Potassium-Exchanging ATPase | 1988 |
5-(N,N-dimethyl)amiloride-sensitive Na-Li exchange in isolated specimens of human atrium.
Topics: Amiloride; Antiporters; Carrier Proteins; Heart Atria; Humans; Intracellular Fluid; Ion Channels; Kinetics; Lithium; Membrane Potentials; Potassium Channels; Sodium; Sodium Channels; Sodium-Hydrogen Exchangers | 1988 |
Arginine vasopressin enhances pHi regulation in the presence of HCO3- by stimulating three acid-base transport systems.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonia; Animals; Arginine Vasopressin; Bicarbonates; Biological Transport; Cells, Cultured; Glomerular Mesangium; Hydrogen-Ion Concentration; Kinetics; Male; Rats | 1989 |
The pH of spontaneously beating cultured rat heart cells is regulated by an ATP-calmodulin-dependent Na+/H+ antiport.
Topics: Adenosine Triphosphate; Amiloride; Animals; Calmodulin; Cells, Cultured; Culture Media; Deoxyglucose; Female; Heart Ventricles; Hydrogen; Hydrogen-Ion Concentration; Myocardium; Rats; Sodium; Trifluoperazine | 1989 |
Ha-ras activates the Na+/H+ antiporter by a protein kinase C-independent mechanism.
Topics: Alkaloids; Amiloride; Bombesin; Carrier Proteins; Cells, Cultured; Fibroblasts; Genes, ras; Growth Substances; Hydrogen-Ion Concentration; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1989 |
Sodium transfer from endolymph through a luminal amiloride-sensitive channel.
Topics: Amiloride; Animals; Bumetanide; Ear, Inner; Endolymph; Epithelium; Furosemide; Labyrinthine Fluids; Membrane Potentials; Models, Biological; Ouabain; Perilymph; Rana esculenta; Sodium; Sodium Channels | 1989 |
Synergistic release of arachidonic acid from platelets by activators of protein kinase C and Ca2+ ionophores. Evidence for the role of protein phosphorylation in the activation of phospholipase A2 and independence from the Na+/H+ exchanger.
Topics: Adenosine Triphosphate; Alkaloids; Amiloride; Arachidonic Acids; Aspirin; Blood Platelets; Calcimycin; Carrier Proteins; Enzyme Activation; Humans; Indoles; Ionomycin; Ionophores; Kinetics; Lactams; Phospholipases; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1989 |
Synergistic alpha-1 and alpha-2 adrenergic stimulation of rat proximal nephron Na+/H+ exchange.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Carrier Proteins; Drug Synergism; In Vitro Techniques; Ion Exchange; Kidney Tubules, Proximal; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium Radioisotopes; Sodium-Hydrogen Exchangers | 1989 |
Modulation of agonist-activated calcium influx by extracellular pH in rat pancreatic acini.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetates; Acetic Acid; Amiloride; Ammonium Chloride; Animals; Atropine; Calcium; Calcium Radioisotopes; Carbachol; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lanthanum; Pancreas; Rats; Rats, Inbred Strains; Sincalide | 1989 |
Mechanism of chloride uptake in rabbit corneal epithelium.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Barium; Barium Compounds; Bicarbonates; Biological Transport, Active; Cell Membrane; Chlorides; Colforsin; Cornea; Epithelium; Furosemide; In Vitro Techniques; Kinetics; Potassium; Rabbits; Sodium; Theophylline | 1989 |
Inhibition of brush-border membrane Na+-H+ exchanger by loperamide.
Topics: Amiloride; Carrier Proteins; Drug Interactions; Female; Humans; Kinetics; Loperamide; Microvilli; Naloxone; Piperidines; Placenta; Reference Values; Sodium-Hydrogen Exchangers | 1987 |
Effects of phenothiazines on the Na+-H+ exchanger of the brush-border membrane from the proximal small intestine of the rabbit.
Topics: Amiloride; Animals; Carrier Proteins; Chlorpromazine; Glucose; In Vitro Techniques; Intestine, Small; Kinetics; Microvilli; Phenothiazines; Potassium Chloride; Proline; Rabbits; Sodium; Sodium-Hydrogen Exchangers | 1988 |
The Na+/H+ exchanger in immature and mature granulocytic HL-60 cells. Property changes induced by intracellular acidification and cell maturation.
Topics: Amiloride; Carrier Proteins; Cytoplasm; Dimethadione; Dimethyl Sulfoxide; Fluoresceins; Fluorescent Dyes; Granulocytes; Hydrogen-Ion Concentration; Kinetics; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1988 |
Effects of recombinant human granulocyte-macrophage colony-stimulating factor on intracellular pH in mature granulocytes.
Topics: Amiloride; Antibodies, Monoclonal; Carrier Proteins; Colony-Stimulating Factors; Cytosol; Glycolysis; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Growth Substances; Hydrogen-Ion Concentration; Mitochondria; N-Formylmethionine Leucyl-Phenylalanine; Ouabain; Receptors, Formyl Peptide; Receptors, Immunologic; Recombinant Proteins; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1988 |
Dependence of Na+/H+ antiport activation in cultured rat aortic smooth muscle on calmodulin, calcium, and ATP. Evidence for the involvement of calmodulin-dependent kinases.
Topics: Adenosine Triphosphate; Amiloride; Ammonium Chloride; Animals; Calcium; Calmodulin; Carrier Proteins; Deoxyglucose; Ethers; Hydrogen-Ion Concentration; Ionomycin; Muscle, Smooth, Vascular; Protein Kinases; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers | 1988 |
The effects of alterations in membrane sodium transport on rat aortic smooth muscle proliferation.
Topics: Amiloride; Animals; Aorta; Carrier Proteins; Cell Division; Cell Membrane; Cells, Cultured; In Vitro Techniques; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1988 |
Intracellular pH regulation in resting and contracting segments of rat mesenteric resistance vessels.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Fluoresceins; Hydrogen-Ion Concentration; In Vitro Techniques; Isometric Contraction; Mesenteric Arteries; Muscle, Smooth, Vascular; Nigericin; Norepinephrine; Rats; Vascular Resistance; Vasoconstriction | 1988 |
Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.
Topics: Amiloride; Carrier Proteins; Cell Adhesion; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Pyrazines; Receptors, Cell Surface; Receptors, Transferrin; Sodium-Hydrogen Exchangers | 1985 |
The Na+/H+ antiport is activated by serum and phorbol esters in proliferating myoblasts but not in differentiated myotubes. Properties of the activation process.
Topics: Amiloride; Animals; Blood; Carrier Proteins; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Epidermal Growth Factor; Hydrogen-Ion Concentration; Kinetics; Muscle Development; Phorbol Esters; Phorbols; Rats; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1985 |
The amiloride sensitive Na+/H+ antiport in guinea pig pancreatic acini. Characterization and stimulation by caerulein.
Topics: Amiloride; Animals; Carrier Proteins; Ceruletide; Dose-Response Relationship, Drug; Guinea Pigs; Kinetics; Pancreas; Potassium; Pyrazines; Sodium; Sodium-Hydrogen Exchangers | 1985 |
Stimulation of the T3-T cell receptor-associated Ca2+ influx enhances the activity of the Na+/H+ exchanger in a leukemic human T cell line.
Topics: Amiloride; Antibodies, Monoclonal; Antigens, Surface; Calcium; Carrier Proteins; Cell Line; Humans; Hydrogen-Ion Concentration; Lanthanum; Leukemia, Lymphoid; Phorbol Esters; Receptors, Immunologic; Sodium-Hydrogen Exchangers; T-Lymphocytes | 1985 |
The activity of the Na+/H+ antiporter in cultured cardiac cells is dependent on the culture conditions used.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Chickens; Culture Media; Enzyme Activation; Hydrogen-Ion Concentration; Myocardium; Nigericin; Phosphatidylinositols; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1986 |
Regulation of intracellular pH in human platelets. Effects of thrombin, A23187, and ionomycin and evidence for activation of Na+/H+ exchange and its inhibition by amiloride analogs.
Topics: Amiloride; Blood Platelets; Body Fluids; Calcimycin; Carrier Proteins; Ethers; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ionomycin; Nigericin; Prostaglandin D2; Prostaglandins D; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thrombin; Time Factors | 1986 |
Na+-H+ exchanger of human placental brush-border membrane: identification and characterization.
Topics: Amiloride; Carrier Proteins; Cations, Monovalent; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Microvilli; Placenta; Pregnancy; Sodium; Sodium-Hydrogen Exchangers | 1986 |
Characterization of the Na+/H+ exchanger during maturation of HL-60 cells induced by dimethyl sulfoxide.
Topics: Amiloride; Carrier Proteins; Cell Line; Dimethyl Sulfoxide; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia, Myeloid, Acute; Lithium; Ouabain; Sodium; Sodium-Hydrogen Exchangers | 1987 |
Stimulation by serum of the Na+/H+ antiporter in quiescent pig kidney epithelial (LLC-PK1) cells and role of the antiporter in the reinitiation of DNA synthesis.
Topics: Amiloride; Animals; Blood; Carrier Proteins; DNA Replication; Hydrogen-Ion Concentration; Kidney; Sodium-Hydrogen Exchangers; Swine; Thymidine | 1987 |
Na+ for H+ exchange in rabbit erythrocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Animals; Bumetanide; Carrier Proteins; Cesium; Choline; Drug Resistance; Erythrocytes; Hydrogen-Ion Concentration; Lithium; Male; Ouabain; Phloretin; Potassium; Rabbits; Sodium; Sodium-Hydrogen Exchangers | 1987 |
Evidence for a Na+/H+ exchanger at the basolateral membranes of the isolated frog skin epithelium: effect of amiloride analogues.
Topics: Amiloride; Animals; Biological Transport; Carrier Proteins; Epithelium; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Ouabain; Protons; Rana esculenta; Skin; Sodium; Sodium-Hydrogen Exchangers | 1987 |
Activation of the Na+/H+ and Cl-/HCO3- exchange by stimulation of acid secretion in the parietal cell.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Aminacrine; Animals; Anti-Ulcer Agents; Bicarbonates; Cell Membrane; Chlorides; Cimetidine; Cytosol; Gastric Acid; Histamine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Kinetics; Parietal Cells, Gastric; Rabbits; Sodium | 1988 |
Protection of Ehrlich ascites tumor cells against the antiproliferative effect of mechlorethamine (nitrogen mustard) by 5-N,N-dimethylamiloride.
Topics: Amiloride; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Division; Choline; DNA, Neoplasm; Mechlorethamine; Tumor Cells, Cultured | 1988 |
Amiloride and 5-N,N-dimethylamiloride inhibit the carrier mediated uptake of choline in Ehrlich ascites tumor cells.
Topics: Amiloride; Animals; Binding, Competitive; Carcinoma, Ehrlich Tumor; Carrier Proteins; Choline; Choline Kinase; Kinetics; Sodium | 1987 |
Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange.
Topics: Amiloride; Animals; Carrier Proteins; Cell Line; Epidermal Growth Factor; Humans; Kinetics; Mice; Mice, Inbred BALB C; Mitosis; Protein Biosynthesis; Protons; Pyrazines; RNA; Sodium; Sodium-Hydrogen Exchangers | 1984 |
Chemical stimulation of Na transport through amiloride-blockable channels of frog skin epithelium.
Topics: 4-Chloromercuribenzenesulfonate; Amiloride; Animals; Binding, Competitive; Epithelium; Guanidines; In Vitro Techniques; Ion Channels; Pyrazines; Rana ridibunda; Skin; Sodium; Trinitrobenzenesulfonic Acid | 1983 |
Restoration of normal pH triggers ischemia-reperfusion injury in lung by Na+/H+ exchange activation.
Topics: Amiloride; Animals; Capillary Permeability; Hemodynamics; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Microcirculation; Pulmonary Circulation; Rats; Rats, Inbred Strains; Reperfusion Injury; Sodium-Hydrogen Exchangers | 1995 |
Effects of Na+/H+ antiport and intracellular pH in the regulation of HL-60 cell apoptosis.
Topics: Amiloride; Apoptosis; DNA Damage; Enzyme Inhibitors; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Indoles; Ionophores; Maleimides; Monensin; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1995 |
Na+/H+ exchange in pulmonary artery smooth muscle from spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Amiloride; Animals; Aorta; Hydrogen-Ion Concentration; Hypertension; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Hydrogen Exchangers; Temperature | 1995 |
Proton release from HeLa cells and alkalization of cytoplasm induced by diferric transferrin or ferricyanide and its inhibition by the diarylsulfonylurea antitumor drug N-(4-methylphenylsulfonyl)-N'-(4-cholorophenyl) urea (LY181984).
Topics: Amiloride; Antineoplastic Agents; Calibration; Cytoplasm; Drug Interactions; Ferricyanides; Fluoresceins; Fluorescence; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Protons; Sodium; Stimulation, Chemical; Sulfonylurea Compounds; Transferrin | 1995 |
Responses of salivary acinar cells to intracellular alkalinization.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Ammonium Chloride; Animals; Bumetanide; Butyrates; Butyric Acid; Calcium; Cells, Cultured; Charybdotoxin; Hydrogen-Ion Concentration; Kinetics; Male; Nigericin; Ouabain; Potassium; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Submandibular Gland; Time Factors; Valinomycin | 1994 |
Mechanisms of dopamine effects on Na-K-ATPase activity in Madin-Darby canine kidney (MDCK) epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3',5'-Cyclic-AMP Phosphodiesterases; Amiloride; Animals; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dogs; Domperidone; Dopamine; Dopamine D2 Receptor Antagonists; Epithelium; Ergolines; Furosemide; Isoquinolines; Kidney; Kidney Tubules, Collecting; Piperazines; Protein Kinase C; Quinpirole; Receptors, Dopamine D1; Sodium-Potassium-Exchanging ATPase | 1995 |
Combined therapy with dimethylthiourea, diltiazem and amiloride/dimethylamiloride in the ischemic/reperfused heart.
Topics: Amiloride; Animals; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endocardium; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Thiourea | 1995 |
Activity and expression of the Na+/H+ exchanger in human endothelial cells cultured in high glucose.
Topics: Amiloride; Cell Division; Cells, Cultured; Culture Techniques; Diabetic Nephropathies; Diuretics; Endothelium, Vascular; Fibronectins; Gene Expression; Glucose; Humans; Hypertonic Solutions; RNA, Messenger; Signal Transduction; Sodium; Sodium-Hydrogen Exchangers; Umbilical Veins | 1995 |
Neutrophil functional responses depend on immune complex valency.
Topics: Amiloride; Antibodies; Antigen-Antibody Complex; Calcium; Cells, Cultured; Cytochrome c Group; Cytoplasmic Granules; Cytosol; Flow Cytometry; Fluorescence; Humans; Hydrogen-Ion Concentration; Leukocyte Elastase; Membrane Potentials; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Pancreatic Elastase; Receptors, IgG; Respiratory Burst; Signal Transduction; Stimulation, Chemical; Superoxide Dismutase | 1995 |
Basolateral localization of Na(+)-HCO3- cotransporter activity in alveolar epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Carrier Proteins; Cell Membrane; Cell Size; Cells, Cultured; Epithelium; Hydrogen-Ion Concentration; Male; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Sodium; Sodium Bicarbonate; Sodium-Bicarbonate Symporters | 1995 |
Antidiuretic hormone decreases the intracellular pH in distal nephron epithelium (A6) by inhibiting Na+/H+ exchange.
Topics: Amiloride; Amphibians; Animals; Bicarbonates; Bucladesine; Cyclic AMP; Epithelium; Hydrogen-Ion Concentration; Microscopy, Fluorescence; Nephrons; Sodium-Hydrogen Exchangers; Vasotocin | 1995 |
Hypercapnic acidosis and dimethyl amiloride reduce reperfusion induced cell death in ischaemic ventricular myocardium.
Topics: Acidosis; Amiloride; Animals; Cell Death; Hydrogen-Ion Concentration; Hypercapnia; In Vitro Techniques; Myocardial Reperfusion Injury; Myocardium; Papillary Muscles; Rabbits; Sodium-Hydrogen Exchangers | 1995 |
Characterization of Na+ transport across the cell membranes of the ascending thin limb of Henle's loop.
Topics: Amiloride; Animals; Cell Membrane; Cell Membrane Permeability; Cricetinae; Furosemide; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Loop of Henle; Male; Mesocricetus; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Trichlormethiazide | 1995 |
Protein kinase C inhibits Na(+)-K(+)-2Cl- cotransporter activity in cultured rabbit nonpigmented ciliary epithelium.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Chlorides; Ciliary Body; Potassium; Protein Kinase C; Rabbits; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1994 |
Characterization of plasma membrane Na+/H+ exchange in eel (Anguilla anguilla) intestinal epithelial cells.
Topics: Amiloride; Animals; Buffers; Cell Membrane; Cell Survival; Eels; Epithelial Cells; Epithelium; Hydrogen-Ion Concentration; Intestinal Mucosa; Potassium; Sodium; Sodium-Hydrogen Exchangers | 1995 |
Prolonged hypoxia increases pulmonary vascular smooth muscle cytosolic calcium.
Topics: Amiloride; Amlodipine; Animals; Calcium; Cattle; Cytosol; Hypoxia; In Vitro Techniques; Muscle, Smooth, Vascular; Pulmonary Artery | 1994 |
Polarized distribution of Na(+)-H+ antiport activity in rat alveolar epithelial cells.
Topics: Amiloride; Animals; Buffers; Cell Polarity; Epithelial Cells; Epithelium; Homeostasis; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Tissue Distribution | 1994 |
Regulation of intracellular pH in cardiac muscle during cell shrinkage and swelling in anisosmolar solutions.
Topics: Amiloride; Animals; Cells, Cultured; Electric Stimulation; Female; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Hypertonic Solutions; Male; Membrane Potentials; Microelectrodes; Myocardium; Osmolar Concentration | 1994 |
Effect of high osmolality on Na+/H+ exchange in renal proximal tubule cells.
Topics: Amiloride; Animals; Blotting, Western; Cell Line; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Hypertonic Solutions; Immunoblotting; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Male; Microvilli; Molecular Weight; Rabbits; Recombinant Fusion Proteins; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 1994 |
Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties.
Topics: Amiloride; Animals; Cell Line; Cricetinae; Cricetulus; DNA, Complementary; Guanidines; Myocardial Ischemia; Recombinant Proteins; Sodium-Hydrogen Exchangers; Sulfones; Transfection | 1993 |
Intracellular pH and Ca2+ homeostasis in the pH paradox of reperfusion injury to neonatal rat cardiac myocytes.
Topics: Amiloride; Animals; Animals, Newborn; Calcium; Cells, Cultured; Coronary Disease; Homeostasis; Hydrogen-Ion Concentration; Intracellular Membranes; Myocardial Reperfusion Injury; Myocardium; Rats | 1993 |
Therapeutic potential of analogues of amiloride: inhibition of the regulation of intracellular pH as a possible mechanism of tumour selective therapy.
Topics: Amiloride; Animals; Carrier Proteins; Cell Survival; Cricetinae; Cricetulus; Fluorometry; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Mice; Neoplasms, Experimental; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1993 |
Calcium-mediated intracellular acidification and activation of Na(+)-H+ exchange in adrenal glomerulosa cells stimulated with potassium.
Topics: Aldosterone; Amiloride; Angiotensin II; Animals; Calcium; Carrier Proteins; Cattle; Cells, Cultured; Cytosol; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Potassium; Sodium; Sodium-Hydrogen Exchangers; Zona Glomerulosa | 1993 |
Calcium mobilization-associated and independent cytosolic acidification elicited in tandem with Na+/H+ exchanger activation in target cell-adherent human NK cells.
Topics: Amiloride; Bicarbonates; Calcium; Carrier Proteins; Cell Adhesion; Chlorides; Cytosol; Cytotoxicity, Immunologic; Humans; Hydrogen-Ion Concentration; Killer Cells, Natural; Lymphocyte Activation; Sodium; Sodium-Hydrogen Exchangers | 1993 |
Evidence against a requirement for Na+/H+ exchange activity for proliferation or differentiation of HL60 leukemic cells.
Topics: Amiloride; Bicarbonates; Calcitriol; Carrier Proteins; Cell Adhesion; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Interferon-gamma; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Mechanisms of sodium transport at the blood-brain barrier studied with in situ perfusion of rat brain.
Topics: Amiloride; Animals; Biological Transport; Blood-Brain Barrier; Brain; Bumetanide; Carrier Proteins; Cerebrovascular Circulation; Frontal Lobe; Hydrochlorothiazide; Kinetics; Perfusion; Plasma Volume; Rats; Rats, Inbred Strains; Sodium; Sodium Channels; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters | 1996 |
The role of Na+/H+ exchange and growth factors in pulmonary artery smooth muscle cell proliferation.
Topics: Alkalies; Amiloride; Animals; Cattle; Cell Division; Epidermal Growth Factor; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Pulmonary Artery; Sodium-Hydrogen Exchangers | 1996 |
Angiotensin II stimulation of the basolateral located Na+/H+ antiporter in eel (Anguilla anguilla) enterocytes.
Topics: Amiloride; Amino Acid Sequence; Angiotensin II; Anguilla; Animals; Antibodies, Monoclonal; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Mucosa; Kinetics; Mammals; Molecular Sequence Data; Receptors, Angiotensin; Sodium-Hydrogen Exchangers | 1996 |
A possible mechanism for the inhibition of blood platelet aggregation by pyridoxal-5'-phosphate.
Topics: Adenosine Diphosphate; Amiloride; Aniline Compounds; Blood Platelets; Calcimycin; Calcium; Cytosol; Fluorescent Dyes; Humans; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Spectrometry, Fluorescence; Thrombin; Xanthenes | 1996 |
A dopamine transporter in human erythrocytes: modulation by insulin.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Biological Transport; Carrier Proteins; Catecholamines; Choline; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Epinephrine; Erythrocytes; Humans; Hydrogen-Ion Concentration; Insulin; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Piperazines; Probenecid; Reserpine; Time Factors | 1996 |
Protein kinase C in intracellular pH regulation in alveolar type II cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acids; Amiloride; Animals; Bicarbonates; Buffers; Extracellular Space; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Sodium; Tetradecanoylphorbol Acetate | 1996 |
Differential regulation of cell cycle machinery by various antiproliferative agents is linked to macrophage arrest at distinct G1 checkpoints.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Antineoplastic Agents; Base Sequence; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; DNA; DNA-Binding Proteins; E2F Transcription Factors; G1 Phase; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Molecular Sequence Data; Oncogene Proteins; Phosphorylation; Proto-Oncogene Proteins; Retinoblastoma Protein; Retinoblastoma-Binding Protein 1; Transcription Factor DP1; Transcription Factors | 1996 |
Impact of extracellular buffer composition on cardioprotective efficacy of Na+/H+ exchanger inhibitors.
Topics: Amiloride; Animals; Bicarbonates; Buffers; Dose-Response Relationship, Drug; Extracellular Space; Guanidines; Heart; HEPES; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones | 1996 |
Protective effects of dimethyl amiloride against postischemic myocardial dysfunction in rabbit hearts: phosphorus 31-nuclear magnetic resonance measurements of intracellular pH and cellular energy.
Topics: Acidosis; Adenosine Triphosphate; Amiloride; Animals; Bicarbonates; Calcium; Calcium Chloride; Cardioplegic Solutions; Diastole; Energy Metabolism; Heart; Heart Arrest, Induced; Hydrogen-Ion Concentration; Ischemia; Magnesium; Magnetic Resonance Spectroscopy; Myocardial Contraction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Phosphates; Phosphocreatine; Phosphorus Isotopes; Potassium Chloride; Rabbits; Sodium; Sodium Chloride; Sodium-Hydrogen Exchangers; Ventricular Function, Left; Ventricular Pressure | 1996 |
Cardiac efficiency is improved after ischemia by altering both the source and fate of protons.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Amiloride; Animals; Dichloroacetic Acid; Glucose; Glycolysis; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Oxidation-Reduction; Palmitic Acid; Protons; Rats; Rats, Sprague-Dawley; Time Factors; Tricarboxylic Acids | 1996 |
Granulocyte colony-stimulating factor-stimulated proliferation of myeloid cells: mode of cell cycle control by a range of inhibitors.
Topics: Amiloride; Animals; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cell Division; Cell Line; Cyclic AMP; DNA; Granulocyte Colony-Stimulating Factor; Interferon-alpha; Interferon-gamma; Lipopolysaccharides; Mice; Phosphorylation; Protein Binding; Recombinant Proteins; Stimulation, Chemical | 1996 |
Protective effects of extracellular acidosis and blockade of sodium/hydrogen ion exchange during recovery from metabolic inhibition in neuronal tissue culture.
Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Extracellular Space; Female; Hydrogen; Hydrogen-Ion Concentration; Ionophores; Neuroprotective Agents; Pregnancy; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium-Hydrogen Exchangers | 1996 |
Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model.
Topics: Action Potentials; Amiloride; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Pacing, Artificial; Coloring Agents; Disease Models, Animal; Diuretics; Electrocardiography; Eosine Yellowish-(YS); Hematoxylin; Hemodynamics; Hydrogen; Infusions, Intravenous; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Necrosis; Pericardium; Phosphotungstic Acid; Sodium; Swine; Tachycardia, Ventricular; Tetrazolium Salts | 1996 |
Isovolumetric regulation of C6 rat glioma cells in hyperosmotic media.
Topics: Acids; Amiloride; Animals; Bumetanide; Carrier Proteins; Culture Media; Enzyme Inhibitors; Extracellular Space; Glioma; Osmolar Concentration; Ouabain; Rats; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Temperature; Tumor Cells, Cultured | 1997 |
Ion transport systems in the uptake of 99Tcm-tetrofosmin, 99Tcm-MIBI and 201Tl in a tumour cell line.
Topics: Amiloride; Biological Transport; Bumetanide; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carrier Proteins; Contrast Media; Humans; Kinetics; Organophosphorus Compounds; Organotechnetium Compounds; Ouabain; Potassium; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Technetium Tc 99m Sestamibi; Thallium Radioisotopes; Tumor Cells, Cultured | 1997 |
Thyroid status and regulation of intracellular sodium in rabbit heart.
Topics: Amiloride; Animals; Cells, Cultured; Heart; Heart Ventricles; Homeostasis; Hydrogen-Ion Concentration; Hypothyroidism; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Myocardium; Ouabain; Papillary Muscles; Propylthiouracil; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin; Thyroid Gland; Triiodothyronine | 1997 |
Brain tissue acidosis: effects on the extracellular concentration of N-acetylaspartate.
Topics: Acid-Base Equilibrium; Acidosis; Amiloride; Ammonium Chloride; Animals; Aspartic Acid; Brain; Electric Conductivity; Extracellular Space; Hydrogen-Ion Concentration; Hypercapnia; Lactic Acid; Male; Microdialysis; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley | 1997 |
Egg activation induced by osmotic pressure change and the effects of amiloride on the cryopreservation of mouse oocytes.
Topics: Amiloride; Animals; Cell Nucleus; Cell Survival; Chromosome Aberrations; Cryopreservation; Dimethyl Sulfoxide; Exocytosis; Female; Fertilization in Vitro; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Transport; Mice; Mice, Inbred ICR; Oocytes; Osmotic Pressure; Phosphorylation; Proteins; Sodium-Hydrogen Exchangers | 1996 |
Hypoxia-induced inhibition of the response to nitroxidergic nerve stimulation in canine cerebral arteries.
Topics: Acidosis; Amiloride; Animals; Cerebral Arteries; Dogs; Female; Hypoxia; Male; Nervous System Physiological Phenomena; Neural Inhibition; Nitric Oxide; Stimulation, Chemical; Substance P; Superoxide Dismutase | 1997 |
Is calcium a mediator of infarct size reduction with preconditioning in canine myocardium?
Topics: Amiloride; Animals; Calcium; Calcium Chloride; Coronary Circulation; Dogs; Hemodynamics; Ischemic Preconditioning, Myocardial; Myocardial Infarction | 1997 |
Amiloride analog stimulation of short-circuit current in larval frog skin epithelium.
Topics: Amiloride; Animals; In Vitro Techniques; Ion Channels; Ion Transport; Larva; Nystatin; Rana catesbeiana; Skin; Structure-Activity Relationship | 1997 |
Myocardial dysfunction is associated with activation of Na+/H+ exchange immediately during reperfusion.
Topics: Amiloride; Animals; Cardiotonic Agents; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Time Factors; Ventricular Dysfunction; Ventricular Function | 1997 |
Decreased intracellular pH is not due to increased H+ extrusion in preconditioned rat hearts.
Topics: Amiloride; Animals; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Protons; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Time Factors | 1997 |
The influence of ascorbic acid on active sodium transport in cultured rabbit nonpigmented ciliary epithelium.
Topics: Amiloride; Animals; Ascorbic Acid; Biological Transport, Active; Cell Line; Cells, Cultured; Ciliary Body; Enzyme Inhibitors; Epithelium; Ouabain; Phlorhizin; Pigment Epithelium of Eye; Potassium; Rabbits; Rubidium Radioisotopes; Sodium; Sodium-Potassium-Exchanging ATPase; Spectrophotometry, Atomic | 1998 |
Role for epithelial Na+ channels and putative Na+/H+ exchangers in salt taste transduction in rats.
Topics: Amiloride; Ammonium Chloride; Animals; Chorda Tympani Nerve; Epithelial Cells; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Salts; Signal Transduction; Sodium Channel Blockers; Sodium Channels; Sodium Chloride; Sodium-Hydrogen Exchangers; Taste | 1997 |
Amiloride-induced contraction of isolated guinea pig, mouse, and human fetal airways.
Topics: Acetylcholine; Amiloride; Animals; Animals, Newborn; Cattle; Dogs; Enzyme Inhibitors; Fetus; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Isometric Contraction; Maleimides; Mice; Mice, Inbred C57BL; Muscle, Smooth; Protein Kinase C; Sodium-Hydrogen Exchangers; Species Specificity; Staurosporine; Trachea | 1998 |
Age-related effects of acidosis in isolated cardiac muscle.
Topics: Acidosis; Aging; Amiloride; Analysis of Variance; Animals; Arrhythmias, Cardiac; Diastole; Diuretics; Electrocardiography; Heart; Hydrogen-Ion Concentration; Hypercapnia; Male; Myocardial Contraction; Myocardial Ischemia; Papillary Muscles; Rats; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers; Ventricular Dysfunction, Left; Ventricular Pressure | 1998 |
Technetium-99m-tetrofosmin, technetium-99m-MIBI and thallium-201 uptake in rat myocardial cells.
Topics: Amiloride; Animals; Bumetanide; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Survival; Cells, Cultured; Heart; Ion Transport; Membrane Potentials; Mitochondria, Heart; Monensin; Myocardium; Nigericin; Organophosphorus Compounds; Organotechnetium Compounds; Ouabain; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Sodium; Technetium Tc 99m Sestamibi; Tetrodotoxin; Thallium Radioisotopes | 1998 |
Electroneutral Na+/H+ exchange in brush-border membrane vesicles from Penaeus japonicus hepatopancreas.
Topics: Amiloride; Animals; Calcium; Chlorides; Digestive System; Electrochemistry; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Lithium; Microvilli; Penaeidae; Sodium; Sodium-Hydrogen Exchangers | 1998 |
Extracellulary administered lysophosphatidylcholine causes Ca2+ efflux from freshly isolated adult rat cardiomyocytes.
Topics: Adenosine Triphosphate; Amiloride; Angiotensin II; Animals; Calcium; Cell Membrane; Heart; Lysophosphatidylcholines; Male; Myocardial Contraction; Myocardium; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Calcium Exchanger; Vasoconstrictor Agents | 1998 |
Activators of epithelial Na+ channels inhibit cytosolic feedback control. Evidence for the existence of a G protein-coupled receptor for cytosolic Na+.
Topics: 4-Chloromercuribenzenesulfonate; Amiloride; Animals; Anions; Cells, Cultured; Cytosol; Epithelial Cells; Epithelium; GTP-Binding Proteins; Guanidines; Male; Mice; Receptors, Cell Surface; Salivary Ducts; Sodium Channels; Sulfhydryl Reagents | 1998 |
Amiloride analogs inhibit chronic hypoxic pulmonary hypertension.
Topics: Amiloride; Animals; Blood Pressure; Cell Division; Chronic Disease; Hematocrit; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Vascular Resistance | 1998 |
Independence of dimethylamiloride-sensitive Li+ efflux pathways and Na+-Li+ countertransport in human erythrocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Anions; Antiporters; Bumetanide; Choline; Erythrocytes; Humans; Ion Transport; Lithium; Osmotic Pressure; Ouabain; Phloretin; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1998 |
Polarized distribution of Na+/H+ exchanger isoforms in rabbit collecting duct cells.
Topics: Amiloride; Animals; Base Sequence; Cell Line; Cell Membrane; Cell Polarity; Cimetidine; Clonidine; DNA Primers; Guanidines; Hydrogen-Ion Concentration; Intracellular Fluid; Kidney Tubules, Collecting; Kinetics; Polymerase Chain Reaction; Protein Kinases; Rabbits; Sodium-Hydrogen Exchangers; Sulfones | 1998 |
Altered sodium-hydrogen exchange activity is a mechanism for acid-induced hyperproliferation in Barrett's esophagus.
Topics: Amiloride; Barrett Esophagus; Cell Division; Cell Line; Esophagus; Humans; Hydrogen-Ion Concentration; Kinetics; Mucous Membrane; Organ Culture Techniques; Sodium; Sodium-Hydrogen Exchangers | 1998 |
ETA receptor mediated inhibition of intracellular pH regulation in cultured bovine corneal epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclosporine; Diuretics; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epithelium, Corneal; Hydrogen-Ion Concentration; Immunosuppressive Agents; Intracellular Fluid; Naphthalenes; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Endothelin; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1998 |
Neutrophil degranulation and phospholipase D activation are enhanced if the Na+/H+ antiport is blocked.
Topics: Amiloride; Antigen-Antibody Complex; Cell Degranulation; Cells, Cultured; Cytoplasmic Granules; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Neutrophils; Phospholipase D; Sodium-Hydrogen Exchangers; Superoxides | 1998 |
Regulation of apical membrane Na+/H+ exchangers NHE2 and NHE3 in intestinal epithelial cell line C2/bbe.
Topics: Amiloride; Cell Line; Cell Membrane; Cyclic AMP; Cyclic GMP; Guanidines; Humans; Intestinal Mucosa; Kinetics; Phenotype; Recombinant Proteins; Second Messenger Systems; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones; Tetradecanoylphorbol Acetate; Thapsigargin; Thionucleotides; Time Factors; Transfection | 1998 |
Acetylcholine-induced liquid secretion by bronchial epithelium: role of Cl- and HCO3- transport.
Topics: Acetylcholine; Amiloride; Animals; Bicarbonates; Biological Transport; Bronchi; Bumetanide; Chlorides; Drug Synergism; Epithelium; Swine | 1998 |
Amiloride-insensitive Na+-H+ exchange: a candidate mediator of erythrocyte Na+-Li+ countertransport.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Antiporters; Binding, Competitive; Drug Synergism; Erythrocytes; Humans; Hydrogen-Ion Concentration; Ion Transport; Lithium; Membrane Potentials; Phloretin; Protein Isoforms; Sodium; Sodium-Hydrogen Exchangers; Valinomycin | 1998 |
Regulation of intracellular pH and blood flow in rat duodenal epithelium in vivo.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Amiloride; Ammonium Chloride; Animals; Duodenum; Epithelium; Fluorescent Dyes; Hydrogen; Hydrogen-Ion Concentration; Intestinal Mucosa; Intracellular Membranes; Ionophores; Male; Nigericin; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1999 |
Ethyl isopropylamiloride downregulates Na,K-ATPase gene expression which confers cytotoxicity in primary proximal tubule cell cultures.
Topics: Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Blotting, Northern; Cell Survival; Cells, Cultured; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Rabbits; RNA, Messenger; Sodium-Potassium-Exchanging ATPase | 1998 |
Effects of ion channel modulators in the influx and efflux of Tc-99m-MIBI.
Topics: Adrenal Cortex Neoplasms; Amiloride; Calcium; Calcium Channel Blockers; Calcium Channels; Carcinoma, Small Cell; Flunarizine; Humans; Monensin; Sodium; Sodium Channels; Technetium Tc 99m Sestamibi; Tumor Cells, Cultured; Verapamil | 1999 |
Effect of amiloride analogs on DOCA-salt-induced hypertension in rats.
Topics: Amiloride; Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1999 |
Inhibition of Na+ channel or Na+/H+ exchanger attenuates the hydrogen peroxide-induced derangements in isolated perfused rat heart.
Topics: Amiloride; Analysis of Variance; Animals; Energy Metabolism; Heart; Hydrogen Peroxide; Lipid Peroxidation; Male; Myocardium; Oxidants; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium-Hydrogen Exchangers; Tetrodotoxin | 1999 |
Effect of 5-(N,N-Dimethyl)-amiloride, a specific inhibitor of Na(+)/H(+) exchanger, on the palmitoyl-L-carnitine-induced mechanical and metabolic derangements in the isolated perfused rat heart.
Topics: Amiloride; Animals; Blood Pressure; Energy Metabolism; Enzyme Inhibitors; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Palmitoylcarnitine; Perfusion; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Ventricular Function, Left | 1999 |
Hypericin-induced phototoxicity of human leukemic cell line HL-60 is potentiated by omeprazole, an inhibitor of H+K+-ATPase and 5'-(N,N-dimethyl)-amiloride, an inhibitor of Na+/H+ exchanger.
Topics: Amiloride; Anthracenes; Antineoplastic Agents; Drug Synergism; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia; Omeprazole; Perylene; Radiation-Sensitizing Agents; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1999 |
Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation.
Topics: Adenosine Triphosphate; Amiloride; Ammonium Chloride; Androstadienes; Blood; Blotting, Western; Breast Neoplasms; Cell Line; Cell Movement; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Sodium-Hydrogen Exchangers; Time Factors; Transfection; Tumor Cells, Cultured; Up-Regulation; Wortmannin | 2000 |
Ultrastructural evidence of the protective effect of Na+/H+ exchange inhibition on the in vitro damage induced by ischaemia reperfusion in the interventricular septum of the rabbit heart.
Topics: Amiloride; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Heart Septum; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Rabbits; Sodium-Hydrogen Exchangers | 2000 |
Contrasting role of Na(+) ions in modulating Cu(+2) or Cd(+2) induced hepatocyte toxicity.
Topics: Amiloride; Animals; Cadmium; Calcium; Cell Survival; Cells, Cultured; Copper; Cytosol; Egtazic Acid; Kinetics; Liver; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Sodium | 2000 |
Agonist-induced cytoplasmic volume changes in cultured rabbit parietal cells.
Topics: Amiloride; Animals; Antiporters; Barium; Bumetanide; Carbachol; Carrier Proteins; Cell Size; Cells, Cultured; Chloride-Bicarbonate Antiporters; Cholinergic Agonists; Colforsin; Cytoplasm; Diuretics; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Gastric Acid; Membrane Potentials; Microscopy, Confocal; Osmolar Concentration; Parietal Cells, Gastric; Rabbits; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters | 2000 |
Modulation of the cost of pHi regulation during metabolic depression: a (31)P-NMR study in invertebrate (Sipunculus nudus) isolated muscle.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Carbon Dioxide; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Transport; Magnetic Resonance Spectroscopy; Muscles; Nematoda; Oxygen Consumption | 2000 |
Alteration of intracellular pH and activity of CA3-pyramidal cells in guinea pig hippocampal slices by inhibition of transmembrane acid extrusion.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Amiloride; Animals; Carrier Proteins; Cell Membrane; Fluoresceins; Guinea Pigs; Harmaline; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Membrane Potentials; Pyramidal Cells; Sodium Chloride Symporters; Sodium-Hydrogen Exchangers; Symporters | 2000 |
Heparin-like molecules inhibit pulmonary vascular pericyte proliferation in vitro.
Topics: Amiloride; Animals; Apoptosis; Basement Membrane; Blotting, Western; Cell Cycle; Cell Division; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Glycosaminoglycans; Heparan Sulfate Proteoglycans; Heparin; Lung; Male; Microcirculation; Pericytes; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers | 2000 |
gp120-induced alterations of human astrocyte function: Na(+)/H(+) exchange, K(+) conductance, and glutamate flux.
Topics: Amiloride; Astrocytes; Cells, Cultured; Electric Conductivity; Extracellular Space; Glutamic Acid; HIV Envelope Protein gp120; Humans; Potassium; Protein Isoforms; Sodium; Sodium-Hydrogen Exchangers | 2000 |
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Binding, Competitive; Carbon Radioisotopes; Cations; Cloning, Molecular; DNA-Binding Proteins; DNA, Complementary; Dopamine Agents; Exons; Gene Expression Regulation; HeLa Cells; Herbicides; Humans; In Situ Hybridization; Introns; Kidney; Mice; Niacinamide; Octamer Transcription Factor-3; Oocytes; Pigment Epithelium of Eye; RNA, Messenger; Tetraethylammonium; Transcription Factors; Tritium; Xenopus laevis | 2000 |
Inhibition of Na(+)/H(+) exchange at the beginning of reperfusion is cardioprotective in isolated, beating adult cardiomyocytes.
Topics: Amiloride; Animals; Cell Survival; Cells, Cultured; Hydrogen-Ion Concentration; Myocardial Reperfusion; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Time Factors | 2000 |
Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.
Topics: 3T3 Cells; Amiloride; Animals; Binding Sites; Binding, Competitive; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Culture Media, Serum-Free; Cyclin E; Glycolysis; Humans; Hydrogen-Ion Concentration; Keratinocytes; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Phenotype; S Phase; Sodium-Hydrogen Exchangers; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2000 |
The effect of acidosis on systolic Ca2+ and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes.
Topics: Acidosis; Amiloride; Animals; Butyrates; Caffeine; Calcium; Calcium Channels, L-Type; Cell Separation; Heart Ventricles; Hydrogen-Ion Concentration; Myocardium; Rats; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Systole | 2000 |
Contribution of sodium channel and sodium/hydrogen exchanger to sodium accumulation in the ischemic myocardium.
Topics: Amiloride; Animals; In Vitro Techniques; Ions; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Hydrogen Exchangers; Tetrodotoxin; Ventricular Function, Left | 2000 |
Ion exchange activity in pulmonary artery smooth muscle cells: the response to hypoxia.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Analysis of Variance; Animals; Antiporters; Cats; Cell Hypoxia; Chloride-Bicarbonate Antiporters; Cytoplasm; Female; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Transport; Male; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Pulmonary Artery; Sodium; Sodium-Hydrogen Exchangers | 2001 |
5-(N,N-Dimethyl)-amiloride to discriminate the Unidirectional electrolyte transports in rat small intestine and proximal colon in vivo.
Topics: Amiloride; Animals; Biological Transport; Chlorides; Colon; Duodenum; Electrolytes; Hydrogen-Ion Concentration; Ileum; Intestine, Small; Ion Transport; Jejunum; Male; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers | 1998 |
Endothelin-1 has a unique oxygen-saving effect by increasing contractile efficiency in the isolated rat heart.
Topics: Amiloride; Animals; Antihypertensive Agents; Caffeic Acids; Cardiotonic Agents; Drug Interactions; Endothelin-1; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Oleanolic Acid; Oligopeptides; Oxygen; Perfusion; Piperidines; Rats; Rats, Sprague-Dawley | 2001 |
Gramicidin-perforated patch analysis on HCO3- secretion through a forskolin-activated anion channel in rat parotid intralobular duct cells.
Topics: Amiloride; Animals; Anions; Bicarbonates; Bumetanide; Chlorides; Colforsin; Glyburide; Gramicidin; In Vitro Techniques; Male; Membrane Potentials; Methazolamide; Parotid Gland; Patch-Clamp Techniques; Rats; Rats, Wistar | 2001 |
Dimethylamiloride-induced differentiation of HL-60 cells.
Topics: Amiloride; Cell Division; Cell Transformation, Neoplastic; HL-60 Cells; Humans; Inhibitory Concentration 50 | 2000 |
Acute adaptive cellular base uptake in rat duodenal epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Adaptation, Physiological; Amiloride; Animals; Bicarbonates; Carbon Dioxide; Diffusion; Duodenum; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Mucosa; Rats; Regional Blood Flow | 2001 |
NHE and ICAM-1 expression in hypoxic/reoxygenated coronary microvascular endothelial cells.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Carbocyanines; Cell Hypoxia; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Flow Cytometry; Guanidines; Hydrogen-Ion Concentration; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Male; Microcirculation; Myocardial Reperfusion Injury; Oxygen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Inhibition of the Na(+)/H(+) antiporter suppresses IL-12 p40 production by mouse macrophages.
Topics: Amiloride; Animals; Chemokine CCL4; Chemokine CXCL2; Chemokines; Diuretics; Drug Interactions; Enzyme Activation; Gene Silencing; Interleukin-12; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophage Inflammatory Proteins; Macrophages, Peritoneal; Male; Methacrylates; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Sodium-Hydrogen Exchangers | 2001 |
pH paradox and neonatal heart.
Topics: Acidosis; Amiloride; Animals; Animals, Newborn; Blood Pressure; Calcium; Diastole; Female; Heart Arrest, Induced; Hydrogen; Hydrogen-Ion Concentration; Male; Myocardial Reperfusion Injury; Myocardium; Rabbits; Sodium; Sodium-Hydrogen Exchangers; Temperature | 2001 |
Inhibition of mechanical activation of guinea-pig airway afferent neurons by amiloride analogues.
Topics: Adenosine Triphosphate; Amiloride; Animals; Bronchi; Electrophysiology; Epithelium; Gadolinium; Guinea Pigs; Ion Channel Gating; Mechanoreceptors; Neurons, Afferent; Patch-Clamp Techniques; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Trachea; Vagus Nerve | 2001 |
The effect of 5'-(N,N-dimethyl)-amiloride on cytotoxic activity of doxorubicin and vincristine in CEM cell lines.
Topics: Amiloride; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Humans; Hydrogen-Ion Concentration; Lymphocytes; Sodium-Calcium Exchanger; Tumor Cells, Cultured; Vincristine | 2001 |
Ischemic preconditioning and Na+/H+ exchange inhibition improve reperfusion ion homeostasis.
Topics: Amiloride; Animals; Electrocardiography; Female; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Sodium; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Spectrophotometry, Atomic; Swine | 2002 |
Uptake and processing of Chlamydia trachomatis by human dendritic cells.
Topics: Amiloride; Antigen Presentation; Antigens, Bacterial; Bacterial Adhesion; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Compartmentation; Cells, Cultured; Chaperonin 60; Chlamydia Infections; Chlamydia trachomatis; Clone Cells; Cytokines; Dendritic Cells; Flow Cytometry; Fluorescent Antibody Technique, Indirect; HeLa Cells; Heparin; Heparitin Sulfate; Humans; Lymphocyte Activation; Microscopy, Confocal; Microscopy, Fluorescence; Phagocytosis; Receptors, Antigen, T-Cell, alpha-beta; Vacuoles | 2002 |
Metabolic activation of A549 human airway epithelial cells by organic dust: a study based on microphysiometry.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Bronchi; Cells, Cultured; Cyclic AMP; Drug Interactions; Epithelial Cells; Humans; Lipopolysaccharides; Pertussis Toxin; Sodium-Hydrogen Exchangers; Virulence Factors, Bordetella | 2002 |
Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure.
Topics: Administration, Topical; Amiloride; Animals; Antihypertensive Agents; Aqueous Humor; Bumetanide; Diuretics; Electrophysiology; Female; Intraocular Pressure; Male; Mice; Sodium-Hydrogen Exchangers; Sulfonamides; Thiophenes | 2002 |
Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by HIV-1 protein Vpu.
Topics: Amiloride; Amino Acid Sequence; Anti-HIV Agents; Base Sequence; Biophysical Phenomena; Biophysics; DNA, Viral; HeLa Cells; HIV-1; Human Immunodeficiency Virus Proteins; Humans; Ion Channels; Microscopy, Electron; Molecular Sequence Data; Peptide Fragments; Recombinant Proteins; Viral Regulatory and Accessory Proteins | 2002 |
Enhancement of Ca(2+) transients and contraction of single ventricular myocytes of rats by 5-(N,N-dimethyl) amiloride.
Topics: Amiloride; Animals; Calcium; Cardiomyopathy, Hypertrophic; Heart Ventricles; Myocardial Contraction; Myocytes, Cardiac; Rats; Rats, Wistar; Sodium-Calcium Exchanger | 2002 |
Influence of ANG II on cytoplasmic sodium in cultured rabbit nonpigmented ciliary epithelium.
Topics: Amiloride; Angiotensin II; Animals; Anti-Bacterial Agents; Cells, Cultured; Ciliary Body; Cytoplasm; Enzyme Inhibitors; Epithelial Cells; Hydrogen-Ion Concentration; Macrolides; Osmolar Concentration; Proton-Translocating ATPases; Rabbits; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase | 2002 |
Liquid secretion inhibitors reduce mucociliary transport in glandular airways.
Topics: Acetylcholine; Amiloride; Animals; Anions; Bicarbonates; Bumetanide; Chlorides; In Vitro Techniques; Ion Channels; Mucociliary Clearance; Nitrobenzoates; Swine; Trachea | 2002 |
The role of Na+/H+ exchange in the efficacy of multidose hypothermic cardioplegia in immature rabbit hearts.
Topics: Amiloride; Animals; Animals, Newborn; Cardiac Output; Cardioplegic Solutions; Creatine Kinase; Female; Heart Arrest, Induced; Hemodynamics; Hydrogen-Ion Concentration; Hypothermia, Induced; Male; Myocardial Reperfusion; Myocardium; Organ Culture Techniques; Rabbits; Sodium-Hydrogen Exchangers | 2002 |
The route of bacterial uptake by macrophages influences the repertoire of epitopes presented to CD4 T cells.
Topics: Amiloride; Amino Acid Sequence; Animals; Antigen Presentation; Antigens, Bacterial; Antigens, CD; B7-1 Antigen; B7-2 Antigen; Cadaverine; CD4-Positive T-Lymphocytes; CD40 Antigens; Cell Line; Cytochalasin D; Epitopes; Histocompatibility Antigens Class II; Macrophages; Membrane Glycoproteins; Mice; Microscopy, Electron; Molecular Sequence Data; Streptococcus pyogenes | 2002 |
Noninvasive assessment of aqueous humor turnover in the mouse eye.
Topics: Amiloride; Animals; Aqueous Humor; Female; Fluorescein; Fluorophotometry; Intraocular Pressure; Latanoprost; Levobunolol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pilocarpine; Prostaglandins F, Synthetic; Sodium-Calcium Exchanger | 2003 |
CO2 transduction in avian intrapulmonary chemoreceptors is critically dependent on transmembrane Na+/H+ exchange.
Topics: Amiloride; Animals; Carbon Dioxide; Chemoreceptor Cells; Ducks; Hydrogen-Ion Concentration; Logistic Models; Lung; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 2003 |
[3H]-DA release evoked by low pH medium and internal H+ accumulation in rat hypothalamic synaptosomes: involvement of calcium ions.
Topics: Amiloride; Animals; Calcium; Dopamine; Extracellular Space; Hydrogen-Ion Concentration; Hypothalamus; In Vitro Techniques; Ionophores; Male; Neuroprotective Agents; Nigericin; Potassium Chloride; Protons; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Synaptosomes | 2003 |
Inhibition of apical Na+/H+ exchangers on the macula densa cells augments tubuloglomerular feedback.
Topics: Amiloride; Animals; Arterioles; Cell Polarity; Culture Techniques; Enzyme Inhibitors; Feedback, Physiological; Indazoles; Kidney Glomerulus; Kidney Tubules, Distal; Male; Nitric Oxide Synthase; Rabbits; Renal Circulation; Sodium Chloride; Sodium-Hydrogen Exchangers | 2003 |
Secretion of acid and base equivalents by intact distal airways.
Topics: Acetylcholine; Acid-Base Equilibrium; Acids; Alkalies; Amiloride; Animals; Anti-Bacterial Agents; Biological Transport; Bronchi; Buffers; Chlorides; Enzyme Inhibitors; Hydrogen-Ion Concentration; Macrolides; Sodium Bicarbonate; Swine | 2003 |
Endothelin receptor blockade has an oxygen-saving effect in Dahl salt-sensitive rats with heart failure.
Topics: Amiloride; Animals; Bosentan; Cardiac Output, Low; Echocardiography; Endothelin Receptor Antagonists; Energy Metabolism; Heart Function Tests; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Peptides, Cyclic; Rats; Rats, Inbred Dahl; Receptor, Endothelin A; Receptor, Endothelin B; Sodium-Hydrogen Exchangers; Sulfonamides | 2003 |
Potential new anti-human immunodeficiency virus type 1 compounds depress virus replication in cultured human macrophages.
Topics: Amiloride; Anti-HIV Agents; Cell Division; Cell Survival; Cells, Cultured; DNA, Viral; HIV Core Protein p24; HIV-1; Human Immunodeficiency Virus Proteins; Humans; Macrophages; RNA, Viral; Viral Regulatory and Accessory Proteins; Virus Replication | 2004 |
Measurement of the filtration coefficient (Kfc) in the lung of Gallus domesticus and the effects of increased microvascular permeability.
Topics: Amiloride; Animals; Cadherins; Capillary Permeability; Chickens; Filtration; In Vitro Techniques; Lung; Oleic Acid; Permeability; Respiratory Distress Syndrome; Species Specificity | 2006 |
Epithelial carbonic anhydrases facilitate PCO2 and pH regulation in rat duodenal mucosa.
Topics: Acid-Base Equilibrium; Amiloride; Animals; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Duodenum; Hydrogen-Ion Concentration; Intestinal Mucosa; Male; Methazolamide; Perfusion; Protons; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 2006 |
Influence of fasting on the effects of dimethylamiloride and oxfenicine on ischaemic-reperfused rat hearts.
Topics: Amiloride; Animals; Carnitine O-Palmitoyltransferase; Cell Survival; Enzyme Inhibitors; Fasting; Fatty Acids; Female; Glycine; Glycolysis; In Vitro Techniques; Ion Transport; Ischemic Preconditioning, Myocardial; Lactic Acid; Lipid Metabolism; Male; Muscle Cells; Myocardial Contraction; Myocardial Ischemia; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury | 2006 |
[Effect of the NHE-1-specific inhibitor DMA on pHi, proliferation and apoptosis of HL-60/ADM cells in vitro].
Topics: Amiloride; Apoptosis; Cell Cycle; Cell Proliferation; Doxorubicin; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Sodium-Hydrogen Exchangers | 2006 |
Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum.
Topics: Amiloride; Animals; Benzolamide; Blood Flow Velocity; Capsaicin; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, Animal; Duodenum; Epithelial Cells; Gene Expression; Hydrogen-Ion Concentration; Hyperemia; Intestinal Mucosa; Intracellular Fluid; Laser-Doppler Flowmetry; Male; Methazolamide; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sodium-Calcium Exchanger; TRPV Cation Channels | 2006 |
Mechanisms of secretion-associated shrinkage and volume recovery in cultured rabbit parietal cells.
Topics: Adenosine Triphosphatases; Amiloride; Animals; Carbachol; Cell Size; Cells, Cultured; Charybdotoxin; Chloride Channels; Chromans; Colforsin; Enzyme Inhibitors; Guanidines; Hydrogen-Ion Concentration; Imidazoles; Ion Channels; KCNQ1 Potassium Channel; Nitrobenzoates; Parietal Cells, Gastric; Potassium Channel Blockers; Rabbits; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sulfonamides; Sulfones | 2007 |
HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway.
Topics: Amiloride; Animals; beta-Cyclodextrins; Brefeldin A; Caveolin 1; Cell Hypoxia; Chaperonin 60; Golgi Apparatus; HSC70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Male; Membrane Microdomains; Myocytes, Cardiac; Protein Transport; Rats; Rats, Sprague-Dawley; Secretory Vesicles; Subcellular Fractions | 2007 |
Studies on the mechanisms underlying amiloride enhancement of 3,4-methylenedioxymethamphetamine-induced serotonin depletion in rats.
Topics: Amiloride; Animals; Body Temperature; Corpus Striatum; Drug Synergism; Fever; Hallucinogens; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Serotonin; Serotonin Agents; Sodium Channel Blockers; Sodium-Hydrogen Exchangers | 2007 |
The non-genomic effects on Na+/H+-exchange 1 by progesterone and 20alpha-hydroxyprogesterone in human T cells.
Topics: 20-alpha-Dihydroprogesterone; Adult; Amiloride; Binding, Competitive; Cation Transport Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Immunologic Factors; Intracellular Fluid; Lymphocyte Activation; Male; Mitogens; Phytohemagglutinins; Progesterone; RNA, Messenger; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; T-Lymphocytes; Time Factors | 2007 |
Electron microprobe analysis of rabbit ciliary epithelium indicates enhanced secretion posteriorly and enhanced absorption anteriorly.
Topics: Amiloride; Animals; Aqueous Humor; Cell Size; Chlorides; Ciliary Body; Electron Probe Microanalysis; Enzyme Inhibitors; Epithelial Cells; Gap Junctions; Heptanol; Hypotonic Solutions; In Vitro Techniques; Ouabain; Permeability; Pigment Epithelium of Eye; Potassium; Rabbits; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Time Factors | 2007 |
Protection of ischaemic-reperfused rat heart by dimethylamiloride is associated with inhibition of mitochondrial permeability transition.
Topics: Amiloride; Animals; Cardiovascular Agents; Cell Survival; Cyclosporine; Female; Glycolysis; In Vitro Techniques; Lactic Acid; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Perfusion; Permeability; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2008 |
Intracellular mechanisms and receptor types for endothelin-1-induced positive and negative inotropy in mouse ventricular myocardium.
Topics: Amiloride; Analysis of Variance; Aniline Compounds; Animals; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Endothelin-1; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Mice, Inbred Strains; Myocardial Contraction; Myocytes, Cardiac; Oligopeptides; Peptides, Cyclic; Phenyl Ethers; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers | 2008 |
Solute diffusion through stripped mouse duodenum.
Topics: Amiloride; Animals; Anions; Biological Transport; Carbon Dioxide; Diffusion; Duodenum; Epithelial Cells; Fluoresceins; Fluorescent Dyes; Guanidines; Hydrogen-Ion Concentration; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Pyrazoles; Serotonin; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers; Solutions; Stilbenes | 2007 |
Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes.
Topics: Amiloride; Amino Acids, Cyclic; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Synergism; Homeostasis; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Insulin-Secreting Cells; Keto Acids; Ketoglutarate Dehydrogenase Complex; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Sodium-Calcium Exchanger | 2008 |
Ouabain-induced stimulation of sodium-hydrogen exchange in rat optic nerve astrocytes.
Topics: Amiloride; Ammonium Chloride; Animals; Astrocytes; Boron Compounds; Calcium; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Imidazoles; Ion Channel Gating; Isoquinolines; Optic Nerve; Ouabain; Rats; Sodium; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfonamides | 2008 |
HCO3(-) secretion by murine nasal submucosal gland serous acinar cells during Ca2+-stimulated fluid secretion.
Topics: Amiloride; Animals; Bicarbonates; Calcium Signaling; Carbachol; Cation Transport Proteins; Cell Size; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Cytoplasm; Epithelial Cells; Exocrine Glands; Guanidines; Hydrogen-Ion Concentration; Mice; Mice, Inbred C57BL; Mice, Knockout; Nasal Mucosa; Niflumic Acid; Protein Isoforms; Sodium; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Sulfones | 2008 |
Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE.
Topics: Amiloride; Animals; Biological Transport; Cell Line; Conjunctiva; Enkephalin, Leucine-2-Alanine; Epithelial Cells; Naloxone; Oligopeptides; Opioid Peptides; Organic Anion Transporters; Rabbits; Sodium-Potassium-Exchanging ATPase | 2009 |
Inhibitions of chloride transport and gap junction reduce fluid flow across the whole porcine ciliary epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Aqueous Humor; Bicarbonates; Biological Transport, Active; Blood; Blood-Aqueous Barrier; Bumetanide; Chloride-Bicarbonate Antiporters; Chlorides; Ciliary Body; Gap Junctions; Heptanol; Ion Transport; Niflumic Acid; Pigment Epithelium of Eye; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Calcium Exchanger; Swine | 2009 |
Inhibition of Na+/H+ exchanger enhances low pH-induced L-selectin shedding and beta2-integrin surface expression in human neutrophils.
Topics: Amiloride; Ammonium Chloride; CD11b Antigen; CD18 Antigens; Cell Membrane; Guanidines; Humans; Hydrogen-Ion Concentration; L-Selectin; Lactic Acid; Macrophage-1 Antigen; Metalloproteases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Kinase Inhibitors; Reperfusion Injury; Sodium-Hydrogen Exchangers; Sulfones; Time Factors | 2008 |
Functional coupling of the downregulated in adenoma Cl-/base exchanger DRA and the apical Na+/H+ exchangers NHE2 and NHE3.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Antiporters; Caco-2 Cells; Calcium; Chloride-Bicarbonate Antiporters; Chlorides; Clathrin; Cyclic AMP; Endocytosis; Epithelial Cells; Humans; Intestine, Small; Methazolamide; Mice; Niflumic Acid; Protein Transport; RNA, Messenger; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfate Transporters; Synaptotagmin I; Transfection | 2009 |
Identification of the Na+/H+ exchanger 1 in dorsal root ganglion and spinal cord: its possible role in inflammatory nociception.
Topics: Amiloride; Animals; Behavior, Animal; Blotting, Western; Dose-Response Relationship, Drug; Female; Ganglia, Spinal; Pain; Protein Isoforms; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channel Blockers; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spinal Cord; Time Factors | 2009 |
Dimethyl amiloride, a Na+-H+ exchange inhibitor, and its cardioprotective effects in hemorrhagic shock in in vivo resuscitated rats.
Topics: Amiloride; Animals; Dose-Response Relationship, Drug; Heart Failure; Male; Models, Animal; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Sodium-Hydrogen Exchangers; Time Factors | 2009 |
Elevated hydrostatic pressure activates sodium/hydrogen exchanger-1 in rat optic nerve head astrocytes.
Topics: Amiloride; Animals; Animals, Newborn; Astrocytes; Butadienes; Cells, Cultured; Hydrogen-Ion Concentration; Hydrostatic Pressure; Kidney; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Opossums; Optic Disk; Phosphorylation; Protein Kinase Inhibitors; Rats; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Time Factors | 2009 |
Stimulation by sparkling water of gastroduodenal HCO3- secretion in rats.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Afferent Pathways; Amiloride; Animals; Bicarbonates; Capsaicin; Carbonated Beverages; Dinoprostone; Duodenum; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Water | 2009 |
Non-genomic rapid inhibition of Na+/H+-exchange 1 and apoptotic immunosuppression in human T cells by glucocorticoids.
Topics: Adult; Amiloride; Apoptosis; Cation Transport Proteins; Cell Survival; Dexamethasone; Dose-Response Relationship, Drug; Genome, Human; Glucocorticoids; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Immunosuppression Therapy; Interleukin-2; Interleukin-4; Lymphocyte Activation; Male; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine; Tritium; Young Adult | 2010 |
Hsp60 is actively secreted by human tumor cells.
Topics: Acetylcholinesterase; Amiloride; Apoptosis; beta-Cyclodextrins; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Survival; Chaperonin 60; Culture Media, Conditioned; Exosomes; Extracellular Space; Humans; K562 Cells; Microscopy, Electron, Transmission; Neoplasms | 2010 |
Role of the spinal Na+/H+ exchanger in formalin-induced nociception.
Topics: Amiloride; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Guanidines; Neurons; Pain; Pain Measurement; Pain Threshold; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium-Hydrogen Exchangers; Spinal Cord | 2011 |
Na(+)/H(+) exchanger inhibitor induces vasorelaxation through nitric oxide production in endothelial cells via intracellular acidification-associated Ca2(+) mobilization.
Topics: Amiloride; Animals; Aorta, Thoracic; Calcium; Calmodulin; Cattle; Endoplasmic Reticulum; Endothelial Cells; Guanidines; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sulfones; Vasodilation | 2013 |
Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration.
Topics: Acid Sensing Ion Channels; Acids; Amiloride; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Humans; Longevity; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Motor Neurons; Mutation; Superoxide Dismutase; Superoxide Dismutase-1 | 2013 |
Acid loading stimulates rat glomerular mesangial cells proliferation through Na(+)-H (+) exchanger isoform 1 (NHE1)-dependent pathway.
Topics: Acidosis; Amiloride; Animals; Blotting, Western; Cell Cycle; Cell Proliferation; Disease Progression; Flow Cytometry; Fluoresceins; Hydrogen-Ion Concentration; Mesangial Cells; Rats; Renal Insufficiency, Chronic; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2013 |
Defective postsecretory maturation of MUC5B mucin in cystic fibrosis airways.
Topics: Amiloride; Animals; Bronchi; Bumetanide; Cells, Cultured; Cystic Fibrosis; Humans; In Vitro Techniques; Mucin-5B; Swine; Trachea | 2017 |
Blocking NHE Channels Reduces the Ability of In Vitro Capacitated Mammalian Sperm to Respond to Progesterone Stimulus.
Topics: Acrosome Reaction; Amiloride; Animals; Biomechanical Phenomena; Cell Membrane; Male; Membrane Potential, Mitochondrial; Progesterone; Reactive Oxygen Species; Sodium-Hydrogen Exchangers; Sperm Capacitation; Sperm Motility; Swine | 2021 |