Page last updated: 2024-08-23

amikacin and piperidines

amikacin has been researched along with piperidines in 82 studies

Research

Studies (82)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	40 (48.78)	24.3611
2020's	42 (51.22)	2.80

Authors

Authors	Studies
Hamagami, K; Honma, T; Iwabu, M; Kadowaki, T; Kimura-Someya, T; Matsuda, K; Nagano, T; Ogata, H; Okada-Iwabu, M; Shirouzu, M; Tanabe, H; Tanaka, A; Tokuyama, K; Ueki, K; Yamaguchi, M; Yamauchi, T; Yokoyama, S	1
Holland, WL; Scherer, PE	1
Gao, EH; Koch, WJ; Lau, WB; Li, R; Liang, B; Ma, XL; Wang, YJ; Yuan, YX; Zhang, Y; Zhao, J	1
Schänzer, W; Thevis, M	1
Malih, S; Najafi, R	1
Hill, MA; Hong, K; Lee, S; Li, R; Tanner, MA; Wu, J; Yang, Y	1
Delahaut, P; Dib, J; Fichant, E; Schänzer, W; Thevis, M; Thomas, A	1
Wan, Y; Wang, P; Wang, Y; Wu, G; Xue, X; Ye, B; Ye, G	1
Malih, S; Mansouri, K; Najafi, R; Pourjafar, M; Saidijam, M; Tafakh, MS; Talebzadeh, F	1
Mango, D; Mercuri, NB; Ngomba, RT; Nicoletti, F; Nisticò, R; Piccinin, S; Weisz, F	1
Fairaq, A; Osman, I; Pichavaram, P; Segar, L; Shawky, NM	1
Gordillo, R; Holland, WL; Johnson, JA; Pearson, MJ; Quittner-Strom, E; Scherer, PE; Sharma, AX; Sun, K; Tippetts, TS; Xia, JY	1
Chen, Y; Duan, Y; Han, J; Li, Q; Li, X; Li, Y; Liu, L; Liu, Y; Ma, C; Miao, QR; Sun, L; Yang, X; Yu, M; Zeng, P; Zhang, R; Zhu, Y	1
Du, Y; Gan, L; Gao, E; Guo, R; Koch, W; Lau, WB; Liang, B; Ma, XL; Wang, Y; Yan, W; Yan, Z; Zhao, J	1
Liu, KY; Lu, WY; Wang, SJ	1
Choi, BS; Choi, SR; Kim, EN; Kim, HW; Kim, MJ; Kim, MY; Kim, Y; Kim, YS; Lim, JH; Lim, KM; Park, CW	1
Hu, M; Huang, W; Li, J; Ma, X; Wang, X; Wang, Y; Xu, Q; Zhu, P	1
Chen, H; Jin, LQ; Qu, XH; Xiao, M	1
Li, CX; Lv, JP; Qu, XH; Shi, Y; Xiao, M; Xie, KJ	1
Cai, QJ; Chen, H; Qu, XH; Xiao, M; Xie, KJ	1
Akimoto, M; Kawabata, Y; Maruyama, R; Tajima, Y; Takenaga, K	1
Asano, Y; Fang, F; Hong, W; Lakota, K; Sato, S; Sodin-Semrl, S; Taniguchi, T; Varga, J; Yamashita, T; Yoshizaki, A; Zhou, X	1
Bayer, P; Béchade, C; Chabry, J; Debayle, D; Gay, AS; Guyon, A; Heurteaux, C; Maroteaux, L; Nicolas, S	1
Chen, X; Chi, Y; Guo, J; Huang, Z; Li, A; Lin, W; Ren, Y; So, KF; Sun, X; Wang, P; Xiang, H; Xiang, K; Xu, Y; Zhou, L; Zhou, Q	1
Aoshima, M; Egawa, T; Goto, A; Goto, K; Higa, M; Ikuta, A; Ito, R; Miyata, H; Ohashi, K; Ohno, Y; Yokoyama, S	1
Deng, W; Hu, C; Liao, HH; Tang, QZ; Wang, SS; Wei, WY; Yang, Z; Zhang, N	1
Hu, X; Li, T; Liu, J; Ou-Yang, Q; Wang, L; Xie, X	1
Che, L; Fang, Z; Feng, B; Hua, L; Huang, X; Jiang, D; Jiang, X; Jin, C; Li, J; Li, Z; Lin, Y; Xu, S; Yan, L; Zhu, Y; Zhuo, Y	1
Kim, Y; Park, CW	1
Lu, J; Sun, Z; Wang, Z; Yu, J; Zhang, J; Zheng, J	1
Chen, H; Huang, L; Qu, XH; Xiao, M; Xie, KJ	1
Liang, F; Lu, J; Shao, A; Shi, L; Sun, Z; Xu, W; Yu, J; Zhang, J; Zheng, J	1
Huang, L; Li, X; Qu, XH; Wang, SJ; Xiao, M; Xie, KJ	1
Bauman, WA; Cardozo, CP; Liu, XH; Pan, JP	1
Barner, K; Behbakht, K; Bitler, BG; Hicks, D; Jansson, T; Powell, T; Qamar, L; Ramzan, AA; Wilson, H	1
Ge, Y; Li, X; Liu, Q; Yu, Y; Zhang, Y	1
Aihara, M; Honjo, M; Uchida, T; Ueta, T	1
Chen, J; Chen, Y; Li, PL; Li, X; Umetani, M; Wang, YT; Zhang, Y	1
Edwards, CM; Edwards, JR; Gooding, S; Javaid, MK; Leung, SK; Lwin, ST; Nador, G; Olechnowicz, SWZ; Ramasamy, K; Rao, SR; Weivoda, MM	1
Chapkin, RS; Choate, R; Fuentes, NR; McMurray, DN; Salinas, ML; Wright, RC	1
Bhat, IA; Dar, MO; Kabeer, SW; Mir, RH; Reza, MI	1
Xiao, WZ; Zhang, L	1
Chabry, J; Gautier, N; Nicolas, S; Pisani, DF; Rochet, N	1
Chen, J; Guo, Y; Li, Y; Tang, J; Tu, Q; Wang, C; Wang, Y; Wang, Z	1
Abdel-Rahman, AA; Leffler, KE	1
Duan, ZX; Li, SQ; Li, YH; Li, ZH; Liu, Q; Tu, C; Xie, P	1
Deng, C; Gao, Y; Hu, X; Sha, M; Wan, Y; Wang, Y; Zhuang, Y	1
Abou-Samra, M; Boursereau, R; Brichard, SM; Lecompte, S; Noel, L; Selvais, CM	1
Hao, QQ; Liu, YF; Wang, C; Wang, SJ; Wang, WQ	1
Liu, B; Liu, CL; Liu, J; Wang, JG; Yan, HJ	1
Bunting, M; Chan, KH; Chan, PK; Chu, LW; Chung, SK; Festenstein, R; Iyaswamy, A; Jian, M; Kumar Durairajan, SS; Kwan, JS; Lam, KS; Leung, KM; Li, M; Ma, OK; Ng, RC; Senthilkumar, K; Zhou, GJ	1
Byeon, S; Choi, SK; Haam, CE; Kwon, Y; Lee, YH	1
Chen, C; Cheng, K; Cheng, Y; Dai, L; Li, H; Qian, M; Sun, G; Wang, P; Wen, X; Xu, QL; You, Y; Yuan, H; Zhou, X	1
Botta, A; Elizbaryan, K; Lam, NH; Sweeney, G; Tashakorinia, P	1
Gong, Z; Gu, D; Han, Y; He, D; Ren, H; Shi, Y; Xia, T; Yang, J; Zeng, C	1
Cersosimo, E; Dong, LQ; Terasawa, T; Xu, X	1
Gao, P; Han, Y; Jiang, N; Sun, L; Xiong, S; Zhao, H	1
Li, Y; Ruan, C; Song, B; Xue, W; Zhao, J	1
Dupont, J; Estienne, A; Froment, P; Grandhaye, J; Guerif, F; Hmadeh, S; Jeanpierre, E; LeGuevel, R; Levasseur, F; Levern, Y; Plotton, I; Ramé, C	1
Adjaye, J; Beller, M; Bohndorf, M; Czekelius, C; Fiszl, AR; Graffmann, N; Martins, S; Ncube, A; Reuther, P; Wruck, W	1
Iwabu, M; Kadowaki, T; Kadowaki, Y; Kobori, T; Miyata, K; Odawara, S; Ohuchi, N; Okada-Iwabu, M; Tanabe, H; Yamauchi, T; Yokoyama, S	1
Akimoto, M; Koshikawa, N; Nagase, H; Takenaga, K	1
Akhyari, P; Boeken, U; Chekhoeva, A; Immohr, MB; Jenke, A; Kistner, J; Lichtenberg, A; Miyahara, S; Yazdanyar, M	1
Christie, BR; Lee, TH; Lin, K; Siu, PM; So, KF; van Praag, H; Xu, A; Yau, SY	1
Hu, P; Ji, H; Liu, H; Liu, S; Liu, Y; Luo, E; Zhao, Q	1
Bouslama, R; Forsgård, R; Groop, PH; Lehto, M; Lehtonen, E; Lehtonen, S; Lindfors, S; Mannerla, M; Mirtti, T; Nisen, H; Polianskyte-Prause, Z; Salmenkari, H; Tienari, J	1
Binienda, A; Fichna, J; Kordek, R; Majchrzak, K; Małecka-Panas, E; Salaga, M; Zatorski, H; Zielińska, M	1
Daniele, A; Naviglio, S; Nigro, E; Ragone, A; Salzillo, A; Sapio, L	1
Bossios, A; Malmhäll, C; Rådinger, M; Ramos-Ramírez, P; Tliba, O	1
Albaladejo-Otón, MD; Arnao, MB; Gázquez, A; Larqué, E; Martínez-Gascón, LE; Rodríguez, F; Sánchez-Campillo, M; Saura-Garre, P	1
Christie, BR; Komal, P; Lee, TH; Lin, K; Siu, PM; So, KF; Xu, A; Yau, SY; Yuan, TF; Zhang, L	1
Ghazvini Zadeh, E; Gordillo, R; Guo, Z; Joffin, N; Li, WH; Onodera, T; Scherer, PE; Xu, P; Yu, B	1
Costagliola, C; Daniele, A; Mallardo, M; Nigro, E	1
Gao, P; Han, Y; Jiang, N; Sun, L; Wei, L; Xiao, Y; Xiong, S; Xiong, X; Yang, M; Yang, S; Zhao, H; Zhu, X	1
Liu, X; Niu, Y; Shen, C; Sun, J; Zhang, W	1
El-Sherbiny, M; Helal, MG; Said, E; Salem, HA; Samaha, MM	1
Liu, H; Lu, J; Peng, L; Wang, Y; Wu, J; Xia, B; Xiang, Y; Zhang, R	1
Ambrose, J; Anant, S; Bye, BA; Eades, AE; Jack, JL; Manley, SJ; Messaggio, F; Olou, AA; Ruckert, MT; VanSaun, MN; Walsh, RM	1
Cao, Z; Cui, C; Gao, M; Liu, S; Luan, X; Ma, B; Qiu, Y; Zhao, J; Zheng, Y	1
Anderson, RM; Balasubramanian, P; Baum, S; Colman, RJ; Diffee, GM; Greenman, A; Gustafson, GE; Howell, PR; Lamming, DW; Schaar, AE; Smith, AB	1
Dai, L; Duan, M; Feng, Z; Sun, G; Tai, L; Wang, P; Wang, Q; Xu, X; Yuan, H; Zhang, S	1
Abdel, MP; Berry, DJ; Bettencourt, JW; Carstens, MF; Dudakovic, A; Gow, C; Limberg, AK; Morrey, ME; Payne, AN; Salmons, HI; Sanchez-Sotelo, J	1

Reviews

4 review(s) available for amikacin and piperidines

Article	Year
Human sports drug testing by mass spectrometry. Mass spectrometry reviews, 2017, Volume: 36, Issue:1 Topics: Anabolic Agents; Chromatography, Liquid; Doping in Sports; Gas Chromatography-Mass Spectrometry; Germany; Growth Hormone-Releasing Hormone; Humans; Mass Spectrometry; Peptide Fragments; Phosphodiesterase 4 Inhibitors; Piperidines; Recombinant Fusion Proteins; Somatostatin; Tandem Mass Spectrometry; Testosterone Congeners	2017
Mechanisms of Adiponectin Action: Implication of Adiponectin Receptor Agonism in Diabetic Kidney Disease. International journal of molecular sciences, 2019, Apr-10, Volume: 20, Issue:7 Topics: Adiponectin; Animals; Diabetes Mellitus, Type 2; Humans; Kidney; Lipid Metabolism; Obesity; Oxidative Stress; Piperidines; Receptors, Adiponectin	2019
AdipoRon: A Novel Insulin Sensitizer in Various Complications and the Underlying Mechanisms: A Review. Current molecular pharmacology, 2020, Volume: 13, Issue:2 Topics: Animals; Behavior; Disease; Humans; Insulin; Piperidines; Signal Transduction	2020
AdipoRon and Other Adiponectin Receptor Agonists as Potential Candidates in Cancer Treatments. International journal of molecular sciences, 2021, May-25, Volume: 22, Issue:11 Topics: Animals; Bone Neoplasms; Humans; Neoplasm Proteins; Osteosarcoma; Piperidines; Receptors, Adiponectin	2021

Other Studies

78 other study(ies) available for amikacin and piperidines

Article	Year
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature, 2013, Nov-28, Volume: 503, Issue:7477 Topics: Adenylate Kinase; Adiponectin; Adipose Tissue, White; Administration, Oral; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Evaluation, Preclinical; Dyslipidemias; Enzyme Activation; Glucose Intolerance; Inflammation; Insulin Resistance; Liver; Longevity; Mice; Mitochondria; Muscle Fibers, Skeletal; Muscles; Obesity; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Piperidines; PPAR alpha; Receptors, Adiponectin; Signal Transduction; Small Molecule Libraries; Transcription Factors; Triglycerides	2013
Cell Biology. Ronning after the adiponectin receptors. Science (New York, N.Y.), 2013, Dec-20, Volume: 342, Issue:6165 Topics: Adiponectin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Apoptosis; Ceramidases; Diabetes Mellitus, Experimental; Disease Models, Animal; Hypoglycemic Agents; Insulin Resistance; Mice; Molecular Mimicry; Molecular Targeted Therapy; Obesity; Piperidines; Receptors, Adiponectin	2013
AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent signalings. American journal of physiology. Endocrinology and metabolism, 2015, Aug-01, Volume: 309, Issue:3 Topics: Adiponectin; Administration, Oral; AMP-Activated Protein Kinases; Animals; Apoptosis; Cardiotonic Agents; Heart Ventricles; Hypoglycemic Agents; Male; Mice, Knockout; Mice, Transgenic; Mutant Proteins; Myocardial Ischemia; Myocardial Reperfusion Injury; Oxidative Stress; Piperidines; Random Allocation; Receptors, Adiponectin; Signal Transduction	2015
AdipoRon: a possible drug for colorectal cancer prevention? Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:9 Topics: Adiponectin; AMP-Activated Protein Kinases; Colorectal Neoplasms; Humans; Piperidines; Receptors, Adiponectin; Signal Transduction	2015
Adiponectin Receptor Agonist, AdipoRon, Causes Vasorelaxation Predominantly Via a Direct Smooth Muscle Action. Microcirculation (New York, N.Y. : 1994), 2016, Volume: 23, Issue:3 Topics: Animals; Calcium Signaling; Male; Mice; Muscle, Smooth, Vascular; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Vasodilation	2016
Identification and characterization of in vitro and in vivo generated metabolites of the adiponectin receptor agonists AdipoRon and 112254. Journal of pharmaceutical and biomedical analysis, 2016, Jun-05, Volume: 125 Topics: Animals; In Vitro Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Tandem Mass Spectrometry	2016
Hepatoprotective effects of AdipoRon against d-galactosamine-induced liver injury in mice. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Oct-10, Volume: 93 Topics: Animals; Cell Line, Transformed; Galactosamine; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Piperidines	2016
Promigratory and proangiogenic effects of AdipoRon on bone marrow-derived mesenchymal stem cells: an in vitro study. Biotechnology letters, 2017, Volume: 39, Issue:1 Topics: Animals; Bone Marrow Cells; Cells, Cultured; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mesenchymal Stem Cells; Piperidines; Rats; Rats, Wistar; Receptors, CCR2; Receptors, CXCR4	2017
The role of adiponectin receptors in the regulation of synaptic transmission in the hippocampus. Synapse (New York, N.Y.), 2017, Volume: 71, Issue:5 Topics: Animals; CA1 Region, Hippocampal; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Piperidines; Receptors, Adiponectin; Synaptic Transmission	2017
AdipoRon, an adiponectin receptor agonist, attenuates PDGF-induced VSMC proliferation through inhibition of mTOR signaling independent of AMPK: Implications toward suppression of neointimal hyperplasia. Pharmacological research, 2017, Volume: 119 Topics: AMP-Activated Protein Kinases; Animals; Arteries; Cell Line; Cell Proliferation; Humans; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Neointima; Piperidines; Platelet-Derived Growth Factor; Receptors, Adiponectin; Signal Transduction; TOR Serine-Threonine Kinases	2017
Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis. Molecular metabolism, 2017, Volume: 6, Issue:3 Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Ceramidases; Fatty Liver; Glucose; Hepatocytes; Homeostasis; Insulin; Insulin Resistance; Leptin; Lipid Metabolism; Lipids; Liver; Mice; Mice, Transgenic; Piperidines; Receptors, Adiponectin	2017
Activation of Adiponectin Receptor Regulates Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Inhibits Lesions in ApoE-Deficient Mice. Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:7 Topics: AMP-Activated Protein Kinases; Animals; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Biomarkers; Cholesterol, LDL; Disease Models, Animal; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Hep G2 Cells; Humans; Hypolipidemic Agents; Liver; Male; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Phenotype; Piperidines; Plaque, Atherosclerotic; PPAR gamma; Proprotein Convertase 9; Receptors, Adiponectin; Receptors, LDL; Response Elements; RNA Interference; Signal Transduction; Sterol Regulatory Element Binding Protein 2; Transcriptional Activation; Transfection; Up-Regulation	2017
Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling. Autophagy, 2017, Volume: 13, Issue:11 Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Autophagosomes; Autophagy; Beclin-1; Cells, Cultured; Diabetes Mellitus, Experimental; Lysosomal-Associated Membrane Protein 2; Metalloporphyrins; Mice; Mice, Knockout; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphorylation; Piperidines; Receptors, Adiponectin	2017
Adiponectin receptor agonist AdipoRon suppresses adipogenesis in C3H10T1/2 cells through the adenosine monophosphate‑activated protein kinase signaling pathway. Molecular medicine reports, 2017, Volume: 16, Issue:5 Topics: Acetyl-CoA Carboxylase; Adipogenesis; Adiponectin; AMP-Activated Protein Kinases; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Cell Line; Cell Survival; Fatty Acid-Binding Proteins; Leptin; Mice; Phosphorylation; Piperidines; PPAR gamma; Receptors, Adiponectin; RNA, Messenger; Signal Transduction; Stearoyl-CoA Desaturase	2017
Adiponectin receptor agonist AdipoRon decreased ceramide, and lipotoxicity, and ameliorated diabetic nephropathy. Metabolism: clinical and experimental, 2018, Volume: 85 Topics: Adiponectin; Albuminuria; Animals; Apoptosis; Ceramides; Diabetic Nephropathies; Energy Metabolism; Kidney; Lipid Metabolism; Male; Mice; Oxidative Stress; Phosphorylation; Piperidines; Podocytes	2018
Design, synthesis chalcone derivatives as AdipoR agonist for type 2 diabetes. Chemical biology & drug design, 2018, Volume: 92, Issue:2 Topics: AMP-Activated Protein Kinases; Animals; Cell Line; Chalcones; Cholesterol; Diabetes Mellitus, Experimental; Drug Design; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Piperidines; PPAR alpha; Receptors, Adiponectin; Triglycerides	2018
[The effect of AdipoRon on insulin sensitivity of mouse skeletal muscle cells and its mechanism]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2017, Apr-08, Volume: 33, Issue:4 Topics: Animals; Cell Line; Cell Proliferation; Glucose; Glucose Transporter Type 4; Insulin; Insulin Resistance; Mice; Muscle Fibers, Skeletal; Myoblasts; Phosphoinositide-3 Kinase Inhibitors; Piperidines	2017
[AdipoRon for the treatment of type 2 diabetes in mice and its possible mechanism of the liver]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2016, Mar-08, Volume: 32, Issue:3 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Liver; Male; Mice; Mice, Inbred C57BL; Piperidines	2016
[Intervention effects of oral active AdipoRon on liver oxidative stress in type 2 diabetic mice]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2017, Feb-08, Volume: 33, Issue:2 Topics: Animals; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Piperidines; Receptors, Adiponectin; Superoxide Dismutase	2017
Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis. Cell death & disease, 2018, 07-23, Volume: 9, Issue:8 Topics: Apoptosis; Calcium; Calcium Channels; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Mitochondria; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Piperidines; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, Adiponectin; RNA Interference; RNA, Small Interfering; Signal Transduction; Superoxides	2018
An orally-active adiponectin receptor agonist mitigates cutaneous fibrosis, inflammation and microvascular pathology in a murine model of systemic sclerosis. Scientific reports, 2018, 08-07, Volume: 8, Issue:1 Topics: Administration, Oral; Animals; Bleomycin; Disease Models, Animal; Female; Fibrosis; Humans; Inflammation; Mice, Inbred C57BL; Piperidines; Receptors, Adiponectin; Scleroderma, Systemic; Signal Transduction; Skin; Vascular System Injuries	2018
Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression. Translational psychiatry, 2018, 08-16, Volume: 8, Issue:1 Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Corticosterone; Cytokines; Depression; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Receptors, Adiponectin	2018
Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury. Journal of neurotrauma, 2019, 03-19, Volume: 36, Issue:6 Topics: Adiponectin; Animals; Inflammation; Lipids; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Sheath; Piperidines; Receptors, Adiponectin; Signal Transduction; Spinal Cord Injuries	2019
Activation of adiponectin receptors has negative impact on muscle mass in C2C12 myotubes and fast-type mouse skeletal muscle. PloS one, 2018, Volume: 13, Issue:10 Topics: AMP-Activated Protein Kinases; Animals; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Gene Knockdown Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Muscle, Skeletal; Piperidines; Real-Time Polymerase Chain Reaction; Receptors, Adiponectin	2018
AdipoRon, an adiponectin receptor agonist, attenuates cardiac remodeling induced by pressure overload. Journal of molecular medicine (Berlin, Germany), 2018, Volume: 96, Issue:12 Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cell Differentiation; Fibroblasts; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Rats, Sprague-Dawley; Receptors, Adiponectin; Transforming Growth Factor beta1; Ventricular Remodeling	2018
AdipoRon prevents l-thyroxine or isoproterenol-induced cardiac hypertrophy through regulating the AMPK-related pathway. Acta biochimica et biophysica Sinica, 2019, Jan-01, Volume: 51, Issue:1 Topics: AMP-Activated Protein Kinases; Animals; Atrial Natriuretic Factor; Body Weight; Cardiomegaly; Gene Expression; Isoproterenol; Male; Natriuretic Peptide, Brain; Organ Size; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Piperidines; Rats, Sprague-Dawley; Signal Transduction; Thyroxine	2019
Fibroblast growth factor 21 coordinates adiponectin to mediate the beneficial effects of low-protein diet on primordial follicle reserve. EBioMedicine, 2019, Volume: 41 Topics: Adiponectin; Administration, Oral; Animals; Diet, Protein-Restricted; Female; Fibroblast Growth Factors; In Vitro Techniques; Liver; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Oocytes; Organ Culture Techniques; Ovarian Follicle; Ovary; Piperidines; RNA, Messenger; Signal Transduction	2019
AdipoRon Protects Against Secondary Brain Injury After Intracerebral Hemorrhage via Alleviating Mitochondrial Dysfunction: Possible Involvement of AdipoR1-AMPK-PGC1α Pathway. Neurochemical research, 2019, Volume: 44, Issue:7 Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Brain Injuries; Cerebral Hemorrhage; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria; Necrosis; Neurons; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Piperidines; Reactive Oxygen Species; Receptors, Adiponectin; Signal Transduction	2019
[The intervention effects of AdipoRon on renal injury in type 2 diabetic mice]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2018, Jun-08, Volume: 34, Issue:6 Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Kidney; Male; Mice; Piperidines	2018
AdipoRon Attenuates Neuroinflammation After Intracerebral Hemorrhage Through AdipoR1-AMPK Pathway. Neuroscience, 2019, 08-01, Volume: 412 Topics: Adenylate Kinase; Animals; Anti-Inflammatory Agents; Cerebral Hemorrhage; Disease Models, Animal; Encephalitis; Male; Mice; Neurons; Phosphorylation; Piperidines; Receptors, Adiponectin; Signal Transduction	2019
[Effects of AdipoRon orally on the functions of spleen and pancreas in type 2 diabetic mice]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2019, Volume: 35, Issue:1 Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Inflammation; Insulin; Insulin Receptor Substrate Proteins; Male; Mice; Pancreas; Piperidines; Random Allocation; Receptor, Insulin; Spleen	2019
AdipoRon prevents myostatin-induced upregulation of fatty acid synthesis and downregulation of insulin activity in a mouse hepatocyte line. Physiological reports, 2019, Volume: 7, Issue:13 Topics: AMP-Activated Protein Kinase Kinases; Animals; Cell Line; Fatty Acids; Hepatocytes; Insulin; Mice; Myostatin; Piperidines; PPAR alpha; Protein Kinases; Signal Transduction; Smad Proteins	2019
Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells. Molecular and cellular biochemistry, 2019, Volume: 461, Issue:1-2 Topics: AMP-Activated Protein Kinases; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mechanistic Target of Rapamycin Complex 1; Mitosis; Models, Biological; Neoplasm Grading; Neoplasms, Cystic, Mucinous, and Serous; Ovarian Neoplasms; Piperidines; Receptors, Adiponectin	2019
Characterization of the metabolite of AdipoRon in rat and human liver microsomes by ultra-high-performance liquid chromatography combined with Q-Exactive Orbitrap tandem mass spectrometry. Biomedical chromatography : BMC, 2019, Volume: 33, Issue:11 Topics: Animals; Chromatography, High Pressure Liquid; Humans; Microsomes, Liver; Piperidines; Rats; Tandem Mass Spectrometry	2019
The Neuroprotective Effect of the Adiponectin Receptor Agonist AdipoRon on Glutamate-Induced Cell Death in Rat Primary Retinal Ganglion Cells. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2019, Volume: 35, Issue:10 Topics: Animals; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Neuroprotective Agents; Piperidines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Adiponectin; Retinal Ganglion Cells; Structure-Activity Relationship	2019
Contribution of transcription factor EB to adipoRon-induced inhibition of arterial smooth muscle cell proliferation and migration. American journal of physiology. Cell physiology, 2019, 11-01, Volume: 317, Issue:5 Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Movement; Cell Proliferation; Cells, Cultured; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Piperidines	2019
Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment. Scientific reports, 2019, 10-02, Volume: 9, Issue:1 Topics: Adiponectin; Animals; Bone Marrow; Cell Proliferation; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mice; Multiple Myeloma; Nerve Growth Factor; Neuroglia; NF-kappa B; Osteoblasts; Pain; Peptides; Piperidines; Quinoxalines; Stromal Cells; Tumor Microenvironment; Tumor Necrosis Factor-alpha	2019
AdipoRon Attenuates Wnt Signaling by Reducing Cholesterol-Dependent Plasma Membrane Rigidity. Biophysical journal, 2020, 02-25, Volume: 118, Issue:4 Topics: Animals; Cell Membrane; Cholesterol; Mice; Piperidines; Receptors, Adiponectin; Wnt Signaling Pathway	2020
Adiponectin receptor agonist AdipoRon relieves endotoxin-induced acute hepatitis in mice. Chinese medical journal, 2019, Oct-20, Volume: 132, Issue:20 Topics: Acute Disease; Animals; Apoptosis; Caspases; Disease Models, Animal; Galactosamine; Hepatitis; Hepatocytes; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Piperidines; Receptors, Adiponectin; Transforming Growth Factor alpha	2019
The adiponectin receptor agonist AdipoRon normalizes glucose metabolism and prevents obesity but not growth retardation induced by glucocorticoids in young mice. Metabolism: clinical and experimental, 2020, Volume: 103 Topics: Abdominal Fat; Animals; Bone Development; Carbohydrate Metabolism; Disease Models, Animal; Disease Progression; Glucocorticoids; Glucose; Growth Disorders; Male; Mice; Mice, Inbred C57BL; Obesity; Piperidines; Receptors, Adiponectin	2020
AdipoRon promotes diabetic fracture repair through endochondral ossification-based bone repair by enhancing survival and differentiation of chondrocytes. Experimental cell research, 2020, 02-15, Volume: 387, Issue:2 Topics: Animals; Apoptosis; Bone and Bones; Bone Regeneration; Cartilage; Cell Differentiation; Cell Line; Chondrocytes; Chondrogenesis; Diabetes Mellitus, Type 2; Fracture Healing; Fractures, Bone; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Osteogenesis; Piperidines	2020
Restoration of Adiponectin-Connexin43 Signaling Mitigates Myocardial Inflammation and Dysfunction in Diabetic Female Rats. Journal of cardiovascular pharmacology, 2020, Volume: 75, Issue:3 Topics: Adiponectin; Animals; Arginine; Connexin 43; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Estradiol; Estrogen Receptor alpha; Female; Heme Oxygenase (Decyclizing); Hypertrophy, Left Ventricular; Ovariectomy; Piperidines; Rats, Wistar; Receptors, Adiponectin; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling	2020
Adiponectin receptor agonist AdipoRon attenuates calcification of osteoarthritis chondrocytes by promoting autophagy. Journal of cellular biochemistry, 2020, Volume: 121, Issue:5-6 Topics: Adiponectin; Adolescent; Adult; Aged; AMP-Activated Protein Kinases; Apoptosis; Autophagy; Calcification, Physiologic; Cartilage; Cartilage, Articular; Chondrocytes; Female; Humans; Knee; Male; Microscopy, Fluorescence; Osteoarthritis; Piperidines; Pyrazoles; Pyrimidines; Receptors, Adiponectin; Signal Transduction; TOR Serine-Threonine Kinases; Young Adult	2020
Therapeutic effects of AdipoRon on liver inflammation and fibrosis induced by CCl International immunopharmacology, 2020, Volume: 79 Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Female; Fibrosis; Fluorocarbons; Hepatic Stellate Cells; Hepatitis, Animal; Humans; Inflammation Mediators; Liver; Mice; Mice, Inbred C57BL; Piperidines	2020
AdipoRon, a new therapeutic prospect for Duchenne muscular dystrophy. Journal of cachexia, sarcopenia and muscle, 2020, Volume: 11, Issue:2 Topics: Animals; Female; Humans; Male; Mice; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Piperidines; Survival Analysis	2020
[Adiponectin Receptor Agonist AdipoRon Inhibits the Proliferation of Myeloma Cells via the AMPK/Autophagy Pathway]. Zhongguo shi yan xue ye xue za zhi, 2020, Volume: 28, Issue:1 Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Cell Proliferation; Humans; Multiple Myeloma; Piperidines; Receptors, Adiponectin; Signal Transduction	2020
AdipoRon improves cognitive dysfunction of Alzheimer's disease and rescues impaired neural stem cell proliferation through AdipoR1/AMPK pathway. Experimental neurology, 2020, Volume: 327 Topics: Alzheimer Disease; AMP-Activated Protein Kinases; Animals; Cell Proliferation; Cognition; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Mice; Mice, Transgenic; Neural Stem Cells; Piperidines; Receptors, Adiponectin; Signal Transduction	2020
Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer's disease mouse model. Molecular psychiatry, 2021, Volume: 26, Issue:10 Topics: Administration, Oral; Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Piperidines	2021
AdipoRon, adiponectin receptor agonist, improves vascular function in the mesenteric arteries of type 2 diabetic mice. PloS one, 2020, Volume: 15, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; Insulin Resistance; Male; Mesenteric Arteries; Mice; Mice, Inbred Strains; Nitric Oxide Synthase Type III; Phosphorylation; Piperidines; Receptors, Adiponectin	2020
Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I. European journal of medicinal chemistry, 2020, Aug-15, Volume: 200 Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Electron Transport Complex I; Humans; Mice; Mitochondria; Molecular Structure; Piperidines; Structure-Activity Relationship	2020
An adiponectin-S1P autocrine axis protects skeletal muscle cells from palmitate-induced cell death. Lipids in health and disease, 2020, Jul-01, Volume: 19, Issue:1 Topics: Adiponectin; Animals; Cell Death; Cells, Cultured; Lysophospholipids; Muscle, Skeletal; Myoblasts, Skeletal; Palmitates; Piperidines; Rats; Reactive Oxygen Species; Receptors, Adiponectin; Sphingosine	2020
AdipoRon, an adiponectin receptor agonist, protects contrast-induced nephropathy by suppressing oxidative stress and inflammation via activation of the AMPK pathway. Clinical and experimental nephrology, 2020, Volume: 24, Issue:11 Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Blood Urea Nitrogen; Cell Adhesion Molecules; Cell Line; Contrast Media; Creatinine; Disease Models, Animal; Inflammation; Iohexol; Kidney Diseases; Lactate Dehydrogenases; Male; Oxidative Stress; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Signal Transduction	2020
Anti-inflammatory and anti-proliferative action of adiponectin mediated by insulin signaling cascade in human vascular smooth muscle cells. Molecular biology reports, 2020, Volume: 47, Issue:9 Topics: Adiponectin; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Glucose; Humans; I-kappa B Proteins; Inflammation; Insulin; MAP Kinase Signaling System; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Palmitates; Phosphorylation; Piperidines; Proto-Oncogene Proteins c-akt; Receptors, Adiponectin; Toll-Like Receptor 4; TOR Serine-Threonine Kinases	2020
AdipoRon Protects against Tubular Injury in Diabetic Nephropathy by Inhibiting Endoplasmic Reticulum Stress. Oxidative medicine and cellular longevity, 2020, Volume: 2020 Topics: Animals; Diabetic Nephropathies; Disease Models, Animal; Endoplasmic Reticulum Stress; Humans; Male; Mice; Piperidines	2020
AdipoRon Attenuates Hypertension-Induced Epithelial-Mesenchymal Transition and Renal Fibrosis via Promoting Epithelial Autophagy. Journal of cardiovascular translational research, 2021, Volume: 14, Issue:3 Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Cell Line; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Mice, Inbred C57BL; Phosphorylation; Piperidines	2021
The adiponectin agonist, AdipoRon, inhibits steroidogenesis and cell proliferation in human luteinized granulosa cells. Molecular and cellular endocrinology, 2021, 01-15, Volume: 520 Topics: Adiponectin; AMP-Activated Protein Kinases; Cell Cycle; Cell Proliferation; Cell Survival; Cells, Cultured; Enzyme Activation; Female; Granulosa Cells; Humans; Luteinization; Mitochondria; Models, Biological; Peroxisome Proliferator-Activated Receptors; Piperidines; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Steroids	2021
A stem cell based Biology open, 2021, 01-25, Volume: 10, Issue:1 Topics: Adaptation, Biological; Adiponectin; Biomarkers; Cell Differentiation; Cells, Cultured; Diet, High-Fat; Energy Metabolism; Gene Expression Regulation; Gluconeogenesis; Hepatocytes; Humans; Induced Pluripotent Stem Cells; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Piperidines; Signal Transduction; Stem Cells	2021
AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice. Communications biology, 2021, 01-08, Volume: 4, Issue:1 Topics: Animals; Drug Evaluation, Preclinical; Exercise Tolerance; Insulin Resistance; Male; Mice; Mice, Knockout; Obesity; Piperidines; Receptors, Adiponectin	2021
Obesity reduces the anticancer effect of AdipoRon against orthotopic pancreatic cancer in diet-induced obese mice. Scientific reports, 2021, 02-03, Volume: 11, Issue:1 Topics: Animals; Cell Line, Tumor; Diet, High-Fat; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Male; Mice; Obesity; Pancreatic Neoplasms; Piperidines; Receptors, Adiponectin	2021
AdipoRon Attenuates Inflammation and Impairment of Cardiac Function Associated With Cardiopulmonary Bypass-Induced Systemic Inflammatory Response Syndrome. Journal of the American Heart Association, 2021, 03-16, Volume: 10, Issue:6 Topics: Animals; Cardiopulmonary Bypass; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Male; Myocardial Reperfusion Injury; Piperidines; Rats; Rats, Wistar; Systemic Inflammatory Response Syndrome; Ventricular Function	2021
AdipoRon Treatment Induces a Dose-Dependent Response in Adult Hippocampal Neurogenesis. International journal of molecular sciences, 2021, Feb-19, Volume: 22, Issue:4 Topics: Adiponectin; Aging; Animals; Blood Glucose; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Proliferation; Corticosterone; Dentate Gyrus; Hippocampus; Male; Mice, Inbred C57BL; Models, Biological; Neural Stem Cells; Neurogenesis; Neurons; Piperidines; Spatial Memory	2021
An adiponectin receptor agonist promote osteogenesis via regulating bone-fat balance. Cell proliferation, 2021, Volume: 54, Issue:6 Topics: 3T3 Cells; Animals; Bone and Bones; Bone Regeneration; Cells, Cultured; Disease Models, Animal; Fats; Male; Mice; Osteogenesis; Piperidines; Rats, Sprague-Dawley; Receptors, Adiponectin	2021
Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo. Diabetologia, 2021, Volume: 64, Issue:8 Topics: Aged; Aged, 80 and over; Animals; Calcium-Binding Proteins; Cytokines; Diet, High-Fat; Disease Models, Animal; Endotoxins; Female; Humans; Immunoblotting; Immunohistochemistry; Kidney Glomerulus; Lipopolysaccharides; Male; Mice; Mice, Inbred DBA; Mice, Knockout; Middle Aged; Nephritis; Piperidines; Receptors, Adiponectin; Receptors, G-Protein-Coupled; Transcription Factor RelA	2021
AdipoRon, an Orally Active, Synthetic Agonist of AdipoR1 and AdipoR2 Receptors Has Gastroprotective Effect in Experimentally Induced Gastric Ulcers in Mice. Molecules (Basel, Switzerland), 2021, May-15, Volume: 26, Issue:10 Topics: Administration, Oral; Animals; Catalase; Diclofenac; Disease Models, Animal; Ethanol; Male; Mice; Omeprazole; Oxidative Stress; Peroxidase; Piperidines; Receptors, Adiponectin; Stomach Ulcer; Superoxide Dismutase; Treatment Outcome	2021
Adiponectin/AdipoR1 Axis Promotes IL-10 Release by Human Regulatory T Cells. Frontiers in immunology, 2021, Volume: 12 Topics: Adiponectin; Blood Donors; Cells, Cultured; Forkhead Transcription Factors; Humans; Ikaros Transcription Factor; Inflammation; Interleukin-10; Ligands; p38 Mitogen-Activated Protein Kinases; Piperidines; Receptors, Adiponectin; Signal Transduction; T-Lymphocytes, Regulatory	2021
Adiponectin agonist treatment in diabetic pregnant rats. The Journal of endocrinology, 2021, 07-22, Volume: 251, Issue:1 Topics: Adiponectin; Adiposity; Animals; Birth Weight; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes, Gestational; Female; Male; Oxidative Stress; Piperidines; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats	2021
Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice. Molecular neurobiology, 2021, Volume: 58, Issue:9 Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Proliferation; Dendritic Spines; Diabetes Mellitus, Experimental; Hippocampus; Mice; Neurogenesis; Neuronal Plasticity; Phosphorylation; Physical Conditioning, Animal; Piperidines; Spatial Memory	2021
PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions. Journal of lipid research, 2021, Volume: 62 Topics: Animals; Diet, High-Fat; Glucose; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Piperidines; Polyethylene Glycols	2021
AdipoRon negatively regulates proliferation and migration of ARPE-19 human retinal pigment epithelial cells. Peptides, 2021, Volume: 146 Topics: Adiponectin; Cell Line; Cell Movement; Cell Proliferation; Cytokines; Humans; Piperidines; Retinal Pigment Epithelium	2021
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy. Cell death & disease, 2021, 10-30, Volume: 12, Issue:11 Topics: Adult; AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagosomes; Autophagy; Autophagy-Related Protein-1 Homolog; Cell Line; Diabetic Nephropathies; Enzyme Activators; Female; Fibrosis; Gene Ontology; Glucose; Humans; Intracellular Signaling Peptides and Proteins; Kidney Tubules; Lipid Droplets; Lipid Metabolism; Male; Mice, Inbred C57BL; Microtubule-Associated Proteins; Middle Aged; Oxidative Stress; Phosphorylation; Piperidines; rab7 GTP-Binding Proteins; Receptors, Adiponectin	2021
Adiponectin receptor agonist AdipoRon blocks skin inflamm-ageing by regulating mitochondrial dynamics. Cell proliferation, 2021, Volume: 54, Issue:12 Topics: Animals; Inflammation; Male; Mice; Mitochondria; Mitochondrial Dynamics; Piperidines; Receptors, Adiponectin; Skin Aging	2021
Diacerein versus adipoRon as adiponectin modulators in experimentally-induced end-stage type 2 diabetes mellitus in rats. Environmental toxicology and pharmacology, 2022, Volume: 90 Topics: Adiponectin; Adipose Tissue; Animals; Anthraquinones; Anti-Inflammatory Agents; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Insulin; Male; Muscle, Skeletal; Piperidines; Rats, Sprague-Dawley	2022
AdipoRon exerts opposing effects on insulin sensitivity via fibroblast growth factor 21-mediated time-dependent mechanisms. The Journal of biological chemistry, 2022, Volume: 298, Issue:3 Topics: Animals; Diet, High-Fat; Fibroblast Growth Factors; Glucose Clamp Technique; Insulin; Insulin Resistance; Liver; Mice; Piperidines	2022
Synthetic adiponectin-receptor agonist, AdipoRon, induces glycolytic dependence in pancreatic cancer cells. Cell death & disease, 2022, 02-04, Volume: 13, Issue:2 Topics: Adiponectin; Fatty Acids; Glycolysis; Humans; Pancreatic Neoplasms; Piperidines; Receptors, Adiponectin; Receptors, Artificial	2022
Protective effects of AdipoRon on the liver of Huoyan goose fed a high-fat diet. Poultry science, 2022, Volume: 101, Issue:4 Topics: Adiponectin; Animals; Chickens; Diet, High-Fat; Geese; Inflammation; Lipids; Liver; Piperidines; Receptors, Adiponectin; Transcription Factors	2022
Adiponectin receptor agonist AdipoRon improves skeletal muscle function in aged mice. eLife, 2022, 03-17, Volume: 11 Topics: Adiponectin; Animals; Male; Mice; Muscle, Skeletal; Piperidines; Primates; Quality of Life; Receptors, Adiponectin	2022
Discovery of novel AdipoRon analogues as potent anti-inflammatory agents against nonalcoholic steatohepatitis. European journal of medicinal chemistry, 2022, Dec-15, Volume: 244 Topics: Animals; Anti-Inflammatory Agents; Inflammation; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Piperidines	2022
The Safety of Adiponectin Receptor Agonist AdipoRon in a Rabbit Model of Arthrofibrosis. Tissue engineering. Part C, Methods, 2023, Volume: 29, Issue:4 Topics: Adiponectin; Animals; Dimethyl Sulfoxide; Female; Humans; Mice; Piperidines; Rabbits; Receptors, Adiponectin	2023