amikacin has been researched along with kanamycin a in 875 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 722 (82.51) | 18.7374 |
| 1990's | 13 (1.49) | 18.2507 |
| 2000's | 45 (5.14) | 29.6817 |
| 2010's | 80 (9.14) | 24.3611 |
| 2020's | 15 (1.71) | 2.80 |
| Authors | Studies |
|---|---|
| Brasseur, R; Constantinou-Kokotou, V; Georgiadis, MP; Kotretsou, S; Mingeot-Leclercq, MP; Tulkens, PM | 1 |
| Chaturvedi, AK; Shukla, PK; Singh, RV; Tandon, VK; Yadav, DB | 1 |
| Avison, MB; Okazaki, A | 1 |
| El'Garch, F; Hocquet, D; Jeannot, K; Llanes-Barakat, C; Plésiat, P | 1 |
| Barth, AL; Castanheira, M; Gales, AC; Nicoletti, AG; Pereira, AS; Pignatari, AC | 1 |
| Chen, JH; Shen, GH; Wu, BD; Wu, KM | 1 |
| Au, TK; Chan, EW; Chan, RC; Chin, ML; Chow, VC; Fung, DK; Hawkey, PM | 1 |
| Courvalin, P; Galimand, M; Périchon, B | 1 |
| Castanheira, M; Jones, RN; Mendes, RE; Sader, HS; Toleman, MA; Walsh, TR | 1 |
| Liu, Y; Shi, W; Wang, M; Wu, S; Xu, X; Ye, X; Zhang, Y | 1 |
| Arakawa, Y; Ike, Y; Kimura, K; Kurokawa, H; Shibata, N; Shibayama, K; Suzuki, S; Wachino, J; Yamane, K | 1 |
| Andres, P; Centrón, D; Galas, M; Guerriero, L; Petroni, A; Quiroga, C; Quiroga, MP; Soler Bistué, AJ; Tokumoto, M; Tolmasky, ME; Vargas, LJ; Zorreguieta, A | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L | 1 |
| Connell, TG; Curtis, N; Ritz, N; Robins-Browne, R; Sievers, A; Tebruegge, M | 1 |
| Maurya, HK; Mishra, NN; Shukla, PK; Tandon, VK | 2 |
| Kirikae, T; Kitao, T; Miyoshi-Akiyama, T | 1 |
| Barzilay, EJ; Folster, JP; Rickert, R; Whichard, JM | 1 |
| Govender, K; Govender, P; Govender, T; Kruger, HG; Maguire, GE; Muthusamy, K; Onajole, OK; Pillay, M; van Helden, PD; Wiid, I | 1 |
| Abe, C; Chiba, T; Horita, Y; Inagaki, E; Kuroishi, R; Kurono, Y; Maeda, Y; Mori, M; Nishimura, K; Onozaki, K; Takii, T; Yamamoto, Y | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Kumar, R; Maurya, HK; Shukla, PK; Tandon, VK; Verma, MK | 1 |
| Blango, MG; Mulvey, MA | 1 |
| Brown, JM; Gonoi, T; Ishikawa, J; Kogure, T; Mikami, Y; Shimada, R; Yazawa, K | 1 |
| Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ | 1 |
| Bogaerts, P; Buvens, G; Glupczynski, Y; Lauwers, S; Piérard, D | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Dhamdhere, G; Krishnamoorthy, G; Zgurskaya, HI | 1 |
| Chan, KY; Chang, CW; Litke, AP; Redman, N; Zeng, J; Zhan, J; Zhang, J | 1 |
| Chiba, T; Hasegawa, T; Horita, Y; Kremer, L; Kuroishi, R; Lee, Y; Ogawa, K; Onozaki, K; Sato, Y; Takii, T | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Cai, G; Cho, S; Franzblau, SG; Jaki, BU; Lee, IA; McAlpine, JB; Napolitano, JG; Pauli, GF; Suh, JW; Wang, Y; Yang, SH | 1 |
| Garneau-Tsodikova, S; Green, KD; Houghton, JL; Thamban Chandrika, N | 1 |
| Centárová, I; Cole, ST; Čonka, P; Hrabálek, A; Karabanovich, G; Klimešová, V; Mikušová, K; Němeček, J; Pávek, P; Pávková, I; Roh, J; Šarkan, M; Smutný, T; Stolaříková, J; Székely, R; Vávrová, K; Vejsová, M; Vocat, A; Zemanová, J | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Fridman, M; Herzog, IM; Louzoun Zada, S | 1 |
| Baker, C; Chang, CT; Kawasaki, Y; Shrestha, JP; Subedi, YP; Takemoto, JY; Vincent de Paul, NN | 1 |
| Baasov, T; Belakhov, V; Pokrovskaya, V; Shavit, M | 1 |
| Ashenden, S; Bender, A; Cokol, M; Karakoc, I; Kuru, N; Mason, DJ; Meral, S; Stott, I; Weinstein, ZB | 1 |
| Domalaon, R; Gorityala, BK; Goswami, S; Idowu, T; Lyu, Y; Schweizer, F; Shan, A; Yang, X; Zhanel, GG | 1 |
| Bishai, WR; Duan, G; Gunosewoyo, H; Liu, LL; Lun, S; Tang, J; Xiao, S; Yang, F; Yu, LF; Zhang, W | 1 |
| Bera, S; Mondal, D | 1 |
| Mabhula, A; Singh, V | 1 |
| Canaan, S; Cavalier, JF; Magrioti, V; Mallick, I; Mavrikaki, V; Pagonis, A; Poncin, I | 1 |
| Coppola, WP; Granatek, AP; Kaplan, MA; Nunning, BC | 1 |
| Granatek, AP; Nunning, BC | 2 |
| Harvey, AL; Marshall, IG; Singh, YN | 2 |
| Dahlager, J; Milman, N | 1 |
| Baltar, I; Esplugues, J; Marti, JL; Orts, A | 1 |
| Kondo, S; Takeuchi, T; Umezawa, H; Yagisawa, M | 1 |
| Witchitz, JL | 1 |
| DeFuria, MD; Price, KE; Pursiano, TA | 1 |
| Brumfitt, W; Hamilton-Miller, JM; Reyonolds, AV | 1 |
| Beck, H; Freiesleben, H; Sack, K; Schulz, E; Züllich, B | 1 |
| Amirak, ID; Noone, P; Williams, RJ; Wills, MR | 1 |
| Gutschik, E; Jepsen, OB; Mortensen, I | 1 |
| Block, CS; Cassel, R; Koornhof, HJ; Lewer-Allen, CM; Robinson, RG | 1 |
| Eikenberg, P; Sack, K; Züllich, B | 1 |
| Chudzik, GM; Price, KA | 1 |
| Borowiecka, B; Chojnowski, W | 1 |
| Garcia Rodriguez, JA; Martin Luengo, F; Saenz Gonzalez, MC | 1 |
| Shibata, SA; Yoshikawa, TT | 1 |
| Andrews, JM; Wise, R | 1 |
| Davis, SD; Hyndiuk, RA; Sarff, LD | 1 |
| Knothe, H; Krcméry, V | 1 |
| Okuyama, T; Shimizu, T; Yoshida, U | 1 |
| Babić, I; Hajsig, D; Mostovac, D; Skalova, R | 1 |
| Izawa, T; Katakura, K | 1 |
| Courtieu, AL; Drugeon, HB | 1 |
| Ichiman, Y; Narikawa, S; Takahashi, M; Usui, Y; Yoshida, K | 1 |
| Hirai, CK; Takenaka, IM; Ximenes, J | 1 |
| Hofherr, L; Meyer, M | 1 |
| Gismondo, MR; Nicoletti, G; Russo, G; Toscano, MA | 1 |
| Theopold, HM | 1 |
| Granatek, AP; Nunning, BC; Ricci, RA | 1 |
| Kosakai, N; Oguri, T | 2 |
| Fillastre, JP; Humbert, G; Leroy, A; Oksenhendler, G | 3 |
| Hoogkamp-Korstanje, JA; Westerdaal, NA | 1 |
| Maderazo, EG; Quintiliani, R; Seklecki, MM | 1 |
| Bermúdez, RH; de Brau, CJ; Pérez-Rodríguez, F | 1 |
| Hasegawa, Y; Masaoka, T; Nakamura, H; Shibata, H; Takubo, T; Ueda, T; Yoshitake, J | 1 |
| Forgan-Smith, WR; McSweeney, RJ | 1 |
| Kimura, I; Kitagawa, N; Kitajima, K; Koui, F; Rai, MY; Takahashi, I; Tokioka, M; Yasui, M; Yorimitsu, S; Yoshizawa, K | 1 |
| Coiffier, B; Espinouse, D; Felman, P; Fiere, D; Reynaud, J; Vialard, L; Vu Van, H | 1 |
| Baughman, KL; Edwards, CQ; Lietman, PS; Rogers, JF; Smith, CR | 2 |
| Mandaleris, CD; Sande, MA; Strausbaugh, LJ | 1 |
| Craven, PC; Drutz, DJ; Jorgensen, JH; Kaspar, RL | 1 |
| De Kock, MA; Theron, FP | 1 |
| Axline, SG; Pesanti, EL; Rhame, FS; Yu, VL | 1 |
| Harrison, LH | 1 |
| Bint, AJ; Speller, DC; Stephens, M | 1 |
| Minshew, BH; Schoenknecht, FD; Swanzy, SR | 1 |
| Fortner, CL; Hahn, DM; Schimpff, SC; Standiford, HC; Wiernik, PH; Young, VM | 1 |
| Brewer, NS | 1 |
| Edwards, CQ; Lietman, PS; Maxwell, RR; Rogers, JF; Smith, CR | 1 |
| Dalovisio, JR; Pankey, GA | 3 |
| Fu, KP; Neu, HC | 1 |
| Greenman, RL; Hoffman, TA; Sklaver, AR | 1 |
| Ichikawa, T; Kawada, Y; Kumamoto, Y; Nakano, I; Nishiura, T; Shishido, S; Tsuji, I | 1 |
| Bettelheim, KA; Humble, MW | 1 |
| Armani, U; Astengo, F; Azzena, D | 1 |
| Agudelo, N; de Vidal, EL; Manotas, R; Ramirez, JI; Trujillo, H; Uribe, A; Zapata, CT; Zuluaga, AI | 1 |
| Aboul-Enein, M; Sherif, M; Soliman, O | 1 |
| Frimodt-Möller, N; Madsen, PO; Maigaard, S | 1 |
| McGee, ZA; Meacham, WF; Oldfield, EH; Wirt, TC | 1 |
| Höffler, D | 2 |
| Gioannini, P | 1 |
| Guze, LB; Maitra, SK; Schotz, MC; Steyn, CM; Yoshikawa, TT | 1 |
| Bender, JF; Fortner, CL; Hahn, DM; Love, LJ; Schimpff, SC; Standiford, HC; Wiernik, PH; Young, VM | 1 |
| Federspil, P; Schätzle, W; Schindler, K; Tiesler, E; Weich, C; Ziegler, M | 1 |
| Guze, LB; Maitra, SK; Schotz, MC; Yoshikawa, TT | 1 |
| Fukushima, PI; Traub, WH | 1 |
| Shah, PM; Stille, W | 1 |
| Berger, MB; Martin, RR; Musher, DM; Septimus, EJ; Wallace, RJ | 1 |
| Ball, P; Gray, J | 1 |
| Aguirre, M; Ales, JM; Torres, A | 1 |
| Bartlett, M; Crane, JK; Griffin, PS; Miller, MA; Yousuf, M | 1 |
| Lerner, SA; Perlin, MH | 3 |
| Yoshikawa, TT | 1 |
| Courtieu, AL; Drugeon, HB; Maurisset, B | 1 |
| Tsuchiya, T | 1 |
| Bodey, GP; Feld, R; Rodriguez, V; Valdivieso, M | 3 |
| Ziv, G | 1 |
| Beert, J; Eyckmans, L | 1 |
| Ishigami, J; Kataoka, N; Mayumi, K; Mita, T | 1 |
| Heetderks, G; Shah, RM; Stille, W | 1 |
| Candler, ER; Gangadharam, PR | 1 |
| Dooley, RR; Lau, WK; Osher, AB; Young, LS | 1 |
| Meyer, RD | 2 |
| Glicksman, C; Parsley, TL; Provonchee, RB; Zinner, SH | 1 |
| Minshew, BH; Pollock, HM; Schoenknecht, FD; Sherris, JC | 1 |
| Ilstrup, DM; Kohner, PC; McCall, JT; Snyder, RJ; Washington, JA; Wiltse, CG | 1 |
| Alford, RH; Leonard, JM; McGee, ZA | 1 |
| Agudelo, N; Luisa de Vidal, E; Salgado, H; Trujillo, H; Uribe, A; Zapata, CT; Zuluaga, AI | 1 |
| Curtis, JE; Feld, R; Hasselback, R; Messner, HA; Tuffnell, PG | 1 |
| Chang, CT; Evans, HE; Glass, L; Khan, AJ; Khan, P; Nair, SR | 1 |
| Bodey, GP; Keating, MJ; Rodriguez, V; Valdivieso, M | 1 |
| Kittikul, J; Limsuwan, A; Proomjanyakul, K; Saegcham, K; Siristonpun, Y; Tanpaichritr, D | 1 |
| Garretson, HD; Noonan, JD; Reid, KH; Shields, CB | 1 |
| Kafetzis, DA; Kosmidis, J; Papadatos, CJ; Sinaniotis, CA | 1 |
| De Castro, S; Domínguez-Gil, A; Lanao, JM; Tabernero, JM | 1 |
| Berman, SJ; Boughton, MT; Boughton, WH | 1 |
| Ho, PW; Kominami, N; Pien, FD | 1 |
| Gavan, TL; Schoenknecht, FD; Thornsberry, C; Washington, JA; Yu, PK | 1 |
| Dugal, R; Pechere, JC; Pechere, MM | 1 |
| Coleman, MW; Kinns, M; Sewell, MJ | 1 |
| Fujisawa, K; Kawaguchi, H; Naito, T; Nakagawa, S; Toda, S | 1 |
| Harada, Y; Ishibashi, T; Takamoto, M; Yamada, H | 1 |
| Leidenfrost, U; Nöske, HD; Schröder, R; Sziegoleit, A; Weidner, W | 1 |
| Northrop, DB; Scarbrough, E; Williams, JW | 1 |
| Dominguez-Gil, A; Lanao, JM; Sanchez Tomero, JA; Tabernero, JM | 1 |
| Klastersky, J; Levy, J | 2 |
| Barriere, SL; Conte, JE | 1 |
| Cleary, T; Frankel, LS; Kohl, S; Kramer, WG; Pickering, LK | 1 |
| Darrell, JH; Jones, AK; Want, SV | 1 |
| Duangmani, C; Lexomboon, U; Srimunta, C | 1 |
| Carter, AJ | 1 |
| Auboyer, C; Bouletreau, P; Ducluzeau, R; Etienne, J; Flandrois, JP; Muchada, R | 1 |
| Aranyosi, J; Faragó, E; Gömöry, A; Juhász, I; Kiss, J; Mihóczy, L | 1 |
| Fabre, J; Rudhardt, M | 1 |
| Borowski, J; Dzierzanowska, D; Gruszecki, W; Musierowicz, A; Niedźwiecka, M | 1 |
| Dinwiddie, CB; Isaacs, LL; Luft, FC; Rankin, LI; Sloan, RS; Yum, MN | 1 |
| Alexander, MR; Dull, WL; Kasik, JE | 1 |
| Barry, AL; Fuchs, PC; Gavan, TL; Gerlach, EH; Jones, RN; Sommers, HM | 1 |
| Cleary, TG; Culbert, S; Frankel, LS; Kohl, S; Kramer, WG; Pickering, LK | 1 |
| Gailliard, MC; Kazmierczak, A; Portier, H; Pothier, P; Siebor, E | 1 |
| Acar, JF; Christol, D; Golstein, FW; Pangon, B; Witchitz, JL | 1 |
| Latrille, J; Leng, B; Saux, MC | 1 |
| Humbert, G; Leroy, A; Leroy, J; Moirot, E | 1 |
| Balmayer, B; Despaux, E; Liendo-Liendo, C; Mion, C; Perez, C; Slingeneyer, A | 1 |
| Bergogne-Berezin, E; Berthelot, G; Even, P; Reynaud, P | 1 |
| Bendirjian, JP; Fillastre, JP; Godin, M; Morin, JP | 1 |
| Beaucaire, G; Brion, M; Desaulty, A; Fourrier, A; Marcolin, M; Mouton, Y | 1 |
| Durand, L; Freydiere, AM; Gille, Y; Perrin, P; Vincent, P | 1 |
| Beaufils, F; Chapman, A; David, R; Himmich, H; Loirat, P; Rohan, J; Walme, N | 1 |
| Beck, G; Girard, F; Polu, JM; Puchelle, E; Sadoul, P; Westphal, JC | 1 |
| Gisselbrecht, C; Marty, M; Samson-Lepors, MJ | 1 |
| Doutre, LP; Gomez, E; Roche, MC | 1 |
| Bouvet, A; Desdoits, JM; Morel, CL; Souloy, J | 1 |
| Brunel, D; Despaux, E; Hichri, H; Michel, D; Rodiere, M | 1 |
| Beaufils, F; Binger, E; Blum, C; Guillot, M; Lambert-Zechovsky, N; Mathieu, H | 1 |
| Canton, Ph; Dureux, JB; Etienne, Y; Neiman, L | 1 |
| Bertrand, A; Lepeu, G | 1 |
| Aparicio, M; Aubertin, J; Lacut, JY; Lafontaine, N; Loste, P; Quentin, C; Ragnaud, JM | 1 |
| Ceyrat, J; Flandrois, JP; Marichy, J | 1 |
| Caniggia, M; Garabedian, M; Kiegel, P; Lombard, C; Manelli, JC; Palayret, D; Perez-Cappellano, R | 1 |
| Auboyer, C; Bouletreau, P; Broussole, C; Flandrois, JP; Latarjet, J | 1 |
| Cartier, F; Cormier, M; Dien, G; Guivarch, G; Hoel, JC | 1 |
| Hashimoto, Y; Matsukawa, S; Shima, T | 1 |
| Berger, SA; Pollock, AA; Rahal, JJ; Richmond, AS; Simberkoff, MS | 1 |
| Schiffman, DO | 1 |
| Federspil, P; Schätzle, W; Tiesler, E | 2 |
| Sack, K; Züllich, B | 1 |
| Schassan, HH; Witt, U | 1 |
| Krasemann, C; Mester, U; Stein, HJ | 1 |
| Dusehu, E; Lavalard, JF; Lehtihet, R; Manuel, C; Pangon, B; Preux, MC; Veyssier, P | 1 |
| Hamada, M; Jikihara, T; Miyake, T; Tsuchiya, T; Umezawa, H; Umezawa, S | 1 |
| Black, RE; Hewitt, WL; Lau, WK; Linne, SR; Weinstein, RJ; Winston, DJ; Young, LS | 1 |
| Jevons, S; Moore, JW; Richardson, K; Ross, BC; Wright, JR | 1 |
| Seligman, SJ | 1 |
| Hefelfinger, DC | 1 |
| Hayashi, I; Kaishio, K; Kawamorida, K; Konno, K; Kudo, S; Kurita, K; Nagai, K; Oizumi, K; Watanabe, A | 1 |
| Agbayani, MM; Jhaveri, RC; Khan, AJ | 1 |
| Bergan, T; Melby, K | 1 |
| Finegold, SM; Lewis, RP; Meyer, RD | 2 |
| Bendrick, TW; Brummett, RE; Fox, KE; Himes, DL | 1 |
| Neal, J; Sexton, DJ; Smith, DL | 1 |
| Block, CS; Fabian, B; Robinson, RG | 1 |
| Hashimoto, Y; Matsukawa, S; Satou, M; Shima, T | 2 |
| Naumann, P; Rosin, H | 1 |
| Grunert, K; Kemmerich, B; Koeppe, P; Lode, H | 1 |
| Briedis, DJ; Robson, HG | 2 |
| Mitchard, M; Yates, RA | 1 |
| Andrews, JM; Bedford, KA; Kendall, MJ; Wise, R | 1 |
| Iwao, N; Konya, H; Kuroda, J; Morita, M | 1 |
| Ito, T | 3 |
| Ashby, CD; Lewis, JE; Nelson, JC | 1 |
| Fuchs, P; Lüthy, R; Siegenthaler, W | 1 |
| Gregory, D; Hirschmann, JV | 1 |
| Mirhij, NJ; Myers, MG; Roberts, RJ | 2 |
| Bloch, R; Costello, R; Luft, FC; Maxwell, DR; Sloan, RS; Yum, MN | 1 |
| Sawchuk, RJ; Strate, RG; Zaske, DE | 1 |
| Hull, JH; Sarubbi, FA | 1 |
| Long, CI; Vannatta, JB | 1 |
| Garcia-Rodriguez, JA; Martin-Luengo, F | 1 |
| Kabins, SA; Nathan, C | 1 |
| Borkowski, A; Czaplicki, M; Malewski, AW; Wencel, J | 1 |
| Anttila, M; Kangas, L; Kasanen, A; Nieminen, L; Sairio, E | 1 |
| Kangas, L; Kasanen, A; Nieminen, AL; Nieminen, L; Sairio, E | 1 |
| Finkelstein, E; Hall, K | 1 |
| Mitchard, M; Walker, JM; Wise, R | 2 |
| Spaepen, J; Vandepitte, J; Verbist, L | 1 |
| De Temmerman, P; Klastersky, J; Schoutens, E; Van Beerse, D; Yourassowsky, E | 1 |
| Vander Linden, MP; Yourassowsky, E | 1 |
| Hull, R; Klinger, JD; Moody, EE | 1 |
| Grunert, K; Koeppe, P; Langmaack, H; Lode, H | 3 |
| Hofstetter, A; Staehler, G | 1 |
| Hamory, B; Ignatiadis, P; Sande, MA | 1 |
| Schassan, HH | 2 |
| Cox, CE | 1 |
| Hensgens, C; Klastersky, J; Meunier-Carpentier, F | 1 |
| Agre, K; Berman, E; Gooding, PG; Lane, AZ | 1 |
| Lerner, SA; Pogwizd, SM | 1 |
| Becerra-Muñoz, E; Bravo-Sandoval, J; Cinco-Espinoza, G; Flores-Mercado, F; Galindo-Hernández, E; Ramírez-López, D | 1 |
| Schoutens, E; Vanderlinden, MP; Yourassowsky, E | 2 |
| Hasegawa, Y; Kobayashi, Y; Morishita, T; Tamatani, S; Tomioka, H | 1 |
| Kameyama, A; Maruta, H; Minami, K | 1 |
| Inoue, I; Sakurai, H; Yamagami, K; Yamamoto, K | 1 |
| Kagan, K; Moldover, NH; Rahal, JJ; Simberkoff, MS | 1 |
| Elias, KS; Peter, G; Provonchee, RB; Zinner, SH | 1 |
| Heetderks, G; Shah, PM; Stille, W | 1 |
| Köhler, M; Naumann, P; Reintjens, E; Rosin, H | 1 |
| Kawaguchi, H | 1 |
| Linzenmeier, G; Naumann, P; Neussel, H; Rosin, H | 1 |
| Knothe, H | 1 |
| Acar, JF; Goldstein, F; Le Goffic, F; Talbot, JN; Witchitz, JL | 1 |
| Finland, M; Garner, C; Sabath, LD; Wilcox, C | 1 |
| Berger, J; Cates, CY; Fox, LM; Gurwith, MJ; Lank, BA; Mathias, RG; McCullough, DW; Ronald, AR; Stiver, HG | 1 |
| Dámaso, D; García-Iglesias, MC; Martínez-Beltrán, J; Moreno-López, M | 2 |
| Marget, W; Reindke, B; Versmold, H | 1 |
| Bassoi, ON; de Menezes, JP; Fry, W; Ximenes, J | 1 |
| Kobayashi, Y | 1 |
| Colding, H; Jensen, H; Kampmann, JP; Regeur, L | 1 |
| Carey, JT; Wichter, MD | 1 |
| Courvalin, P; Davies, J | 1 |
| Akiyoshi, M; Akutsu, S; Matsuzaki, M; Tajima, T; Yano, S | 1 |
| Abate, M; Attar, H; Ballard, CA; Bernard, B; Thielen, PF; Wehrle, PF | 1 |
| Hewitt, WL; Young, LS | 1 |
| Kunz, LJ; Moellering, RC; Poitras, JW; Wennersten, C | 1 |
| Cushing, RD; Jauregui, L; Lerner, AM | 1 |
| Doughty, SC; Greenberg, SB; Martin, RR | 1 |
| Blair, DC; Lane, AZ; Wright, GE | 1 |
| Lerner, SA; Matz, GJ; Seligsohn, R | 1 |
| Eubanks, N; Gilbert, DN; Jackson, J | 1 |
| Gorbach, SL; Tally, FP | 2 |
| Bartlett, JG | 1 |
| Levin, S; McKellar, PP; Rivera, N; Trenholme, GM | 1 |
| Yow, MD | 1 |
| Kowarski, A; Lietman, PS; Vogelstein, B | 1 |
| Lietman, PS; McCracken, GH | 1 |
| Ehret, JM; Eickhoff, TC | 1 |
| Daschner, F; Engert, J; Reiss, E | 1 |
| Kornguth, ML; Kunin, CM | 1 |
| Diaz-Gonzales, C; Estopier-Jáuregui, C; Flores-Mercado, F; Galindo-Hernández, E; García-Mercado, JL | 1 |
| Seneca, H | 1 |
| Brummett, RE; Fox, KE | 1 |
| Christensen, EF; Madissoo, H; Reiffenstein, JC | 1 |
| Dzierzanowska, D | 1 |
| Kobayashi, Y; Shigeta, Y; Tomioka, H | 1 |
| de Vidal, EL; García, G; Trujillo, H | 1 |
| Black, RE; Hewitt, WL; Lau, WK; Weinstein, RJ; Young, LS | 1 |
| Sachs, T; Yeivin, R | 1 |
| Hofstetter, A | 1 |
| Klastersky, J; Meunier-Carpentier, F; Prevost, JM; Staquet, M | 1 |
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| Guo, Y; Huang, C; Sha, W; Tan, G; Wu, X; Yang, J; Yu, F | 1 |
| Conkle-Gutierrez, D; Hoffner, SE; Kim, C; Mansjö, M; Modlin, SJ; Ramirez-Busby, SM; Rigouts, L; Valafar, F; Werngren, J | 1 |
| Feng, Z; Gao, Y; Lyu, Y; Rong, Y; Wang, S; Wei, L; Zha, Z | 1 |
| Doustdar, F; Eslami, G; Ghalavand, Z; Habibnia, S; Karami-Zarandi, M; Kazemian, H; Zaker, S | 1 |
| Catanzaro, A; Catanzaro, DG; Chiles, P; Ciobanu, N; Codreanu, A; Colman, RE; Cooney, CG; Crudu, V; Hillery, N; Holmberg, RC; Kukhtin, AV; Linger, Y; Norville, R; Rodwell, TC; Seifert, M; Syed, RR | 1 |
| De Tarafder, A; Gagnon, MG; Ge, X; Parajuli, NP; Sanyal, S; Seely, SM | 1 |
| Berge, I; Bogdanova, I; Freimane, L; Norvaiša, I; Ozere, I; Ranka, R; Sadovska, D; Vaivode, A; Vīksna, A | 1 |
| Jia, AQ; Liu, JS; Wang, W; Zhou, JW | 1 |
24 review(s) available for amikacin and kanamycin a
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Drug-resistance in
Topics: | 2019 |
Antimicrobial agents--Part II. The aminoglycosides: streptomycin, kanamycin, gentamicin, tobramycin, amikacin, neomycin.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Drug Interactions; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Streptomycin; Tobramycin | 1977 |
[Recent views concerning urinary tract infections].
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Sulfonamides; Urinary Tract Infections | 1978 |
[Antibiotic-induced diseases. Aminoglycoside-induced renal lesions].
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Bacterial Infections; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans; Kanamycin; Kidney Diseases; Kidney Function Tests; Sisomicin; Streptomycin; Tobramycin | 1978 |
Determination of aminoglycoside antibiotics in biological fluids: a review.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Biological Assay; Chromatography, Gas; Chromatography, High Pressure Liquid; Gentamicins; Humans; Isotope Labeling; Kanamycin; Mass Spectrometry; Radioimmunoassay; Structure-Activity Relationship; Tobramycin | 1979 |
Deoxygenation of aminoglycosides.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Kanamycin; Molecular Conformation; Structure-Activity Relationship; Tobramycin | 1979 |
[Aminoglycoside antibiotics from clinical viewpoint].
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Combinations; Enterobacteriaceae Infections; Escherichia coli Infections; Gentamicins; Glomerular Filtration Rate; Kanamycin; Klebsiella Infections; Proteus Infections; Providencia; Pseudomonas Infections; Serratia; Sisomicin; Streptomycin; Tobramycin | 1975 |
Aminoglycoside toxicity in infants and children.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Bacterial Infections; Child; Clinical Trials as Topic; Evoked Potentials, Auditory; Gentamicins; Hearing; Humans; Infant; Infant, Newborn; Kanamycin; Kidney; Prospective Studies; Risk; Streptomycin; Tobramycin; Vestibule, Labyrinth | 1986 |
Aminoglycoside antibiotics in infectious diseases. An overview.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Microbial; Drug Therapy, Combination; Endocarditis, Bacterial; Gentamicins; Humans; Kanamycin; Kinetics; Neomycin; Netilmicin; Pneumonia; Sepsis; Sisomicin; Streptomycin; Tobramycin | 1986 |
In vitro evaluations of amikacin: an assessment of the currently used methods of disk diffusion and dilution susceptibility, antimicrobial synergy, and the measurement of amikacin concentrations.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Culture Media; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans; Kanamycin; Lactams; Microbial Sensitivity Tests; Tobramycin | 1986 |
An overview of amikacin.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Proteins; Drug Synergism; Humans; Kanamycin; Lactams; Penicillin Resistance; Penicillins | 1985 |
Role of amikacin in the management of intra-abdominal sepsis.
Topics: Abdomen; Abscess; Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Disease Models, Animal; Drug Resistance, Microbial; Drug Therapy, Combination; Gram-Negative Bacteria; Humans; Kanamycin; Lactams; Peritonitis; Wound Infection | 1985 |
Non-genetic factors affecting hearing development.
Topics: Adult; Age Factors; Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Cochlea; Deafness; Female; Guinea Pigs; Hearing Loss; Hearing Loss, Noise-Induced; Humans; Hyperbilirubinemia; Hypothyroidism; Infant; Infant, Newborn; Kanamycin; Maternal-Fetal Exchange; Pregnancy; Rats | 1985 |
Antimicrobial spectrum, pharmacology, adverse effects, and therapeutic use of amikacin sulfate.
Topics: Amikacin; Bacteria; Drug Resistance, Microbial; Hearing Disorders; Humans; Kanamycin; Kidney Diseases; Kinetics; Neuromuscular Junction | 1981 |
Amikacin.
Topics: Amikacin; Ear Diseases; Humans; Kanamycin; Kidney Diseases; Kinetics | 1981 |
Amikacin: pharmacology, indications and cautions for use, and dose recommendations.
Topics: Amikacin; Central Nervous System; Drug Resistance, Microbial; Female; Half-Life; Humans; Intestinal Absorption; Kanamycin; Kinetics; Pregnancy; Tissue Distribution | 1982 |
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis | 2010 |
Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.
Topics: Acetyltransferases; Amikacin; Anti-Bacterial Agents; Antigens, Bacterial; Bacterial Proteins; Capreomycin; Drug Resistance, Multiple, Bacterial; Humans; Kanamycin; Methyltransferases; Mutation; Mycobacterium tuberculosis; Promoter Regions, Genetic; Tuberculosis, Multidrug-Resistant | 2012 |
Rapid diagnosis of drug resistance to fluoroquinolones, amikacin, capreomycin, kanamycin and ethambutol using genotype MTBDRsl assay: a meta-analysis.
Topics: Amikacin; Antitubercular Agents; Area Under Curve; Capreomycin; Drug Resistance, Bacterial; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Genotype; Humans; Kanamycin; Likelihood Functions; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Odds Ratio; Sensitivity and Specificity | 2013 |
Diagnosis of Drug Resistance to Fluoroquinolones, Amikacin, Capreomycin, Kanamycin and Ethambutol with Genotype MTBDRsl Assay: a Meta-Analysis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple, Bacterial; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Genotyping Techniques; Humans; Kanamycin; Kanamycin Resistance; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant | 2015 |
The safety and tolerability of the second-line injectable antituberculosis drugs in children.
Topics: Adult; Amikacin; Animals; Antitubercular Agents; Capreomycin; Child; Drug Monitoring; Humans; Injections; Kanamycin; Risk Factors; Tuberculosis, Multidrug-Resistant | 2016 |
Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Carbapenems; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Fluoroquinolones; Humans; Kanamycin; Levofloxacin; Linezolid; Moxifloxacin; Recurrence; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2018 |
64 trial(s) available for amikacin and kanamycin a
| Article | Year |
|---|---|
Controlled comparison of amikacin and gentamicin.
Topics: Adult; Aged; Amikacin; Bacteria; Bacterial Infections; Clinical Trials as Topic; Drug Evaluation; Drug Resistance, Microbial; Gentamicins; Hearing Disorders; Humans; Kanamycin; Kidney; Middle Aged; Prospective Studies; Sepsis; Urinary Tract Infections | 1977 |
Treatment of complicated urinary tract infections with amikacin: comparison of low and high dosage.
Topics: Adolescent; Adult; Aged; Amikacin; Escherichia coli; Female; Humans; Kanamycin; Male; Middle Aged; Proteus; Pseudomonas; Urinary Tract Infections | 1977 |
Nephrotoxicity induced by gentamicin and amikacin.
Topics: Adult; Aged; Amikacin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gentamicins; Humans; Kanamycin; Kidney Diseases; Male; Middle Aged; Prospective Studies | 1978 |
[Comparative clinical effect of amikacin and gentamicin on complicated urinary tract infections by doubld-blind method (author's transl)].
Topics: Adult; Aged; Amikacin; Clinical Trials as Topic; Double-Blind Method; Female; Gentamicins; Humans; Kanamycin; Male; Middle Aged; Urinary Tract Infections | 1978 |
Comparison of netilmicin and amikacin in treatment of complicated urinary tract infections.
Topics: Adult; Aged; Amikacin; Clinical Trials as Topic; Gentamicins; Humans; Kanamycin; Kidney; Male; Middle Aged; Netilmicin; Urinary Tract Infections | 1978 |
[Amikacin and gentamicin: a controlled comparison (author's transl)].
Topics: Amikacin; Clinical Trials as Topic; Double-Blind Method; Female; Gentamicins; Humans; Kanamycin; Male; Urinary Tract Infections | 1978 |
Randomized trial of empiric antibiotic therapy with ticarcillin in combination with gentamicin, amikacin or netilmicin in febrile patients with granulocytopenia and cancer.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Gentamicins; Humans; Infections; Kanamycin; Male; Middle Aged; Neoplasms; Penicillin Resistance; Penicillins; Sepsis; Ticarcillin | 1979 |
[Clinical efficacy, nephrotoxicity and ototoxicity of amikacin].
Topics: Adult; Aged; Amikacin; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Female; Hearing; Humans; Kanamycin; Kidney; Male; Middle Aged; Time Factors; Urinary Tract Infections; Vestibule, Labyrinth | 1979 |
[The antibiotic amikacin in various types of infections].
Topics: Adolescent; Adult; Aged; Amikacin; Child; Clinical Trials as Topic; Enterobacteriaceae Infections; Female; Humans; Kanamycin; Male; Middle Aged | 1979 |
Amikacin in the treatment of pyelonephritis.
Topics: Aged; Amikacin; Clinical Trials as Topic; Double-Blind Method; Female; Gentamicins; Glomerular Filtration Rate; Humans; Kanamycin; Kinetics; Male; Pyelonephritis | 1979 |
Comparison of amikacin and tobramycin in the treatment of infection in patients with cancer.
Topics: Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Escherichia coli; Escherichia coli Infections; Female; Humans; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Neoplasms; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Tobramycin; Urinary Tract Infections | 1977 |
A randomized comparative trial of three aminoglycosides--comparison of continuous infusions of gentamicin, amikacin and sisomicin combined with carbenicillin in the treatment of infections in neutropenic patients with malignancies.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Carbenicillin; Drug Therapy, Combination; Female; Gentamicins; Humans; Infusions, Parenteral; Kanamycin; Kidney; Male; Middle Aged; Neoplasms; Neutropenia; Uremia | 1979 |
Comparative efficacy and toxicity of amikacin/carbenicillin versus gentamicin/carbenicillin in leukopenic patients: a randomized prospective trail.
Topics: Adult; Amikacin; Bacterial Infections; Carbenicillin; Drug Synergism; Gentamicins; Hearing Disorders; Humans; Kanamycin; Kidney Diseases; Leukopenia; Penicillin Resistance; Sepsis | 1977 |
[Pharmacologic studies or aminoglycoside antibiotics (amikacin, gentamicin, sisomicin, tobramycin)].
Topics: Adult; Amikacin; Anti-Bacterial Agents; Female; Gentamicins; Humans; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Kinetics; Male; Middle Aged; Sisomicin; Tobramycin | 1978 |
The pharmacokinetics of amikacin and gentamicin in volunteers: a comparison of individual differences.
Topics: Adult; Amikacin; Female; Gentamicins; Half-Life; Humans; Injections, Intravenous; Kanamycin; Kinetics; Male | 1979 |
Clinical and bacteriological evaluation of amikacin in severe gram-negative infections.
Topics: Adult; Aged; Amikacin; Bacteria; Bacterial Infections; Clinical Trials as Topic; Female; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged | 1976 |
[Pharmacokinetics and clinical experience with amikacin. A new aminoglycoside antibiotic].
Topics: Adult; Aged; Amikacin; Aminoglycosides; Biological Availability; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Kanamycin; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Peritonitis; Respiratory Tract Infections; Urinary Tract Infections | 1976 |
[Amikacin in urinary tract infections with so-called problem pathogens].
Topics: Amikacin; Clinical Trials as Topic; Drug Evaluation; Escherichia coli Infections; Humans; Kanamycin; Proteus Infections; Pseudomonas Infections; Urinary Tract Infections | 1976 |
Amikacin Therapy of Urinary tract infections.
Topics: Adolescent; Adult; Aged; Amikacin; Clinical Trials as Topic; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Kanamycin; Male; Middle Aged; Pseudomonas Infections; Urinary Tract Infections | 1976 |
Comparative effectiveness of combinations of amikacin with penicillin G and amikacin with carbenicillin in gram-negative septicemia: double-blind clinical trial.
Topics: Amikacin; Bacterial Infections; Blood Bactericidal Activity; Carbenicillin; Clinical Trials as Topic; Drug Therapy, Combination; Enterobacteriaceae Infections; Humans; Kanamycin; Penicillin G; Pseudomonas Infections; Sepsis | 1976 |
A review of results of clinical trials with amikacin.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Bone Diseases; Child; Child, Preschool; Clinical Trials as Topic; Drug Resistance, Microbial; Enterobacteriaceae Infections; Humans; Infant; Infant, Newborn; Kanamycin; Middle Aged; Pseudomonas Infections; Respiratory Tract Infections; Sepsis; Skin Diseases, Infectious; Urinary Tract Infections | 1976 |
Comparative clinical studies of ototoxicity and nephrotoxicity of amikacin and gentamicin.
Topics: Adult; Amikacin; Gentamicins; Hearing; Humans; Kanamycin; Kidney; Middle Aged | 1977 |
Comparison of amikacin and gentamicin in the treatment of urinary tract infections.
Topics: Adolescent; Adult; Aged; Amikacin; Female; Gentamicins; Humans; Kanamycin; Male; Middle Aged; Prospective Studies; Pyelonephritis; Urinary Tract Infections | 1977 |
Synergism between amikacin and cefazolin against Klebsiella: in vitro studies and effect on the bactericidal activity of serum.
Topics: Aged; Amikacin; Blood Bactericidal Activity; Cefazolin; Cephalosporins; Drug Evaluation; Drug Synergism; Humans; Kanamycin; Klebsiella; Male; Middle Aged; Species Specificity | 1976 |
Amikacin therapy for severe gram-negative sepsis. Emphasis on infections with gentamicin-resistant organisms.
Topics: Aged; Amikacin; Clinical Trials as Topic; Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Gentamicins; Humans; Kanamycin; Male; Middle Aged; Pseudomonas; Pseudomonas Infections | 1975 |
Correlation of serum creatinine concentration and amikacin half-life.
Topics: Adult; Amikacin; Clinical Trials as Topic; Creatinine; Half-Life; Humans; Kanamycin; Kidney Diseases | 1975 |
Enzymuria in aminoglycoside-induced kidney damage. Comparative study of gentamicin, amikacin, sisomicin and netilmicin.
Topics: Adolescent; Adult; Aged; alpha-Glucosidases; Amikacin; Creatinine; Female; gamma-Glutamyltransferase; Gentamicins; Glucosidases; Humans; Kanamycin; Kidney; Male; Middle Aged; Muramidase; Netilmicin; Proteinuria; Sisomicin; Urinary Tract Infections | 1985 |
Aminoglycoside resistance: a worldwide perspective.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Clinical Trials as Topic; Cross Infection; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Kidney; Klebsiella pneumoniae; Lactams; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin | 1986 |
Resistance surveillance programs and the incidence of gram-negative bacillary resistance to amikacin from 1967 to 1985.
Topics: Amikacin; Aminoglycosides; Clinical Trials as Topic; Cross Infection; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Klebsiella; Microbial Sensitivity Tests; Prospective Studies; Pseudomonas aeruginosa; Serratia; Tobramycin; United States | 1986 |
[Comparative clinical trial of HBK and amikacin (AMK) in the treatment of respiratory infections].
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Dibekacin; Double-Blind Method; Female; Humans; Kanamycin; Male; Middle Aged; Respiratory Tract Infections | 1987 |
A double beta-lactam combination versus an aminoglycoside-containing regimen as empiric antibiotic therapy for febrile granulocytopenic cancer patients.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Blood Bactericidal Activity; Blood Coagulation Disorders; Clinical Trials as Topic; Drug Hypersensitivity; Drug Synergism; Drug Therapy, Combination; Fever; Hearing Disorders; Humans; Infections; Kanamycin; Kidney Diseases; Microbial Sensitivity Tests; Middle Aged; Moxalactam; Neoplasms; Piperacillin; Random Allocation | 1986 |
Prospective randomized comparison of three antibiotic regimens for empirical therapy of suspected bacteremic infection in febrile granulocytopenic patients.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Azlocillin; Cefotaxime; Child; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fever; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Kanamycin; Male; Middle Aged; Penicillins; Prospective Studies; Random Allocation; Regression Analysis; Sepsis; Ticarcillin | 1986 |
Aminoglycoside toxicity in infants and children.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Bacterial Infections; Child; Clinical Trials as Topic; Evoked Potentials, Auditory; Gentamicins; Hearing; Humans; Infant; Infant, Newborn; Kanamycin; Kidney; Prospective Studies; Risk; Streptomycin; Tobramycin; Vestibule, Labyrinth | 1986 |
Comparative study of ototoxicity and nephrotoxicity in patients randomly assigned to treatment with amikacin or gentamicin.
Topics: Adolescent; Adult; Aged; Amikacin; Aminoglycosides; Bacterial Infections; Child; Child, Preschool; Clinical Trials as Topic; Female; Gentamicins; Hearing; Humans; Kanamycin; Kidney; Male; Middle Aged; Prospective Studies; Random Allocation | 1986 |
A prospective randomized study comparing the efficacy of Timentin alone or in combination with amikacin in the treatment of febrile neutropenic patients.
Topics: Adolescent; Adult; Aged; Amikacin; Bacteria; Bacterial Infections; Clavulanic Acids; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Fever; Humans; Kanamycin; Male; Middle Aged; Penicillin Resistance; Penicillins; Prospective Studies; Random Allocation; Sepsis; Ticarcillin | 1986 |
Prospective controlled evaluation of auditory function in neonates given netilmicin or amikacin.
Topics: Amikacin; Audiometry, Evoked Response; Bilirubin; Clinical Trials as Topic; Creatinine; Female; Follow-Up Studies; Gentamicins; Hearing Loss, Sensorineural; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Longitudinal Studies; Male; Netilmicin; Prospective Studies | 1985 |
Review of amikacin usage in the EORTC trials.
Topics: Agranulocytosis; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Drug Therapy, Combination; Fever; Gentamicins; Humans; International Cooperation; Kanamycin; Kidney Diseases; Lactams; Neoplasms; Neutropenia | 1985 |
[Use of amikacin in surgical wound infections].
Topics: Amikacin; Bacterial Infections; Clinical Trials as Topic; Humans; Kanamycin; Surgical Wound Infection | 1985 |
Tobramycin and amikacin nephrotoxicity. Value of serum creatinine versus urinary concentration of beta-2-microglobulin.
Topics: Adult; Aged; Amikacin; beta 2-Microglobulin; Clinical Trials as Topic; Creatinine; Humans; Kanamycin; Kidney Diseases; Middle Aged; Prospective Studies; Random Allocation; Tobramycin | 1985 |
Antibiotic resistance patterns during aminoglycoside restriction.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Cross Infection; Drug Resistance, Microbial; Drug Utilization; Escherichia coli; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Pseudomonas aeruginosa; Time Factors | 1985 |
Laboratory and clinical studies on amikacin.
Topics: Amikacin; Bacterial Infections; Clinical Trials as Topic; Drug Resistance, Microbial; Gram-Negative Bacteria; Humans; Kanamycin; Pyelonephritis; Sepsis; Staphylococcus aureus | 1985 |
[Antibiotic therapy of infections in cancer patients with leukopenia].
Topics: Amikacin; Bacterial Infections; gamma-Globulins; Humans; Kanamycin; Leukemia; Leukopenia; Lymphoma; Penicillin G; Sulbenicillin | 1983 |
Empiric antibiotic therapy for suspected infection in granulocytopenic cancer patients: a comparison between the combination of moxalactam plus amikacin and ticarcillin plus amikacin.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Cephalosporins; Cephamycins; Child; Double-Blind Method; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Kanamycin; Male; Middle Aged; Moxalactam; Neoplasms; Penicillins; Prospective Studies; Random Allocation; Ticarcillin | 1982 |
Piperacillin plus amikacin therapy v carbenicillin plus amikacin therapy in febrile, granulocytopenic patients.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Carbenicillin; Child; Child, Preschool; Drug Therapy, Combination; Female; Fever; Humans; Kanamycin; Male; Middle Aged; Penicillins; Piperacillin; Prospective Studies | 1982 |
Single-dose amikacin treatment of first childhood E. coli lower urinary tract infections.
Topics: Amikacin; Child; Child, Preschool; Clinical Trials as Topic; Escherichia coli Infections; Female; Humans; Infant; Injections, Intramuscular; Kanamycin; Sulfisoxazole; Urinary Tract Infections | 1983 |
Combination of amikacin and carbenicillin with or without cefazolin as empirical treatment of febrile neutropenic patients. The International Antimicrobial Therapy Project Group of the European Organization for Research and Treatment of Cancer.
Topics: Agranulocytosis; Amikacin; Bacterial Infections; Carbenicillin; Cefazolin; Clinical Trials as Topic; Drug Therapy, Combination; Fever; Humans; Kanamycin; Kidney Diseases; Neoplasms; Neutropenia | 1983 |
Piperacillin or ticarcillin plus amikacin. A double-blind prospective comparison of empiric antibiotic therapy for febrile granulocytopenic cancer patients.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Fever; Humans; Kanamycin; Leukemia; Male; Middle Aged; Neoplasms; Penicillins; Piperacillin; Prospective Studies; Random Allocation; Ticarcillin | 1981 |
Comparison of the nephrotoxicity and auditory toxicity of tobramycin and amikacin.
Topics: Adult; Aged; Amikacin; Anti-Bacterial Agents; Auditory Threshold; Creatinine; Ear; Female; Humans; Kanamycin; Kidney; Male; Middle Aged; Tobramycin | 1983 |
Reproducibility study of the pharmacokinetics of amikacin, gentamicin and tobramycin; a three-way crossover study.
Topics: Amikacin; Bacteria; Gentamicins; Half-Life; Humans; Kanamycin; Kinetics; Microbial Sensitivity Tests; Tobramycin | 1983 |
A prospective, randomized study of amikacin and gentamicin in serious infections with focus on efficacy, toxicity and duration of serum levels above the MIC.
Topics: Adolescent; Adult; Aged; Amikacin; Bacteria; Bacterial Infections; Ear; Female; Gentamicins; Humans; Kanamycin; Kidney; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Random Allocation | 1983 |
Risk factors for the development of auditory toxicity in patients receiving aminoglycosides.
Topics: Amikacin; Body Temperature; Female; Gentamicins; Hearing Loss; Humans; Kanamycin; Male; Probability; Risk; Sepsis; Statistics as Topic; Time Factors; Tobramycin | 1984 |
Combination of amikacin and either ampicillin or cephalotin as initial treatment of febrile neutropenic patients.
Topics: Adult; Aged; Agranulocytosis; Amikacin; Ampicillin; Bacterial Infections; Cephalothin; Clinical Trials as Topic; Drug Combinations; Female; Fever; Hematologic Diseases; Humans; Kanamycin; Male; Middle Aged; Neutropenia; Prospective Studies; Random Allocation | 1982 |
Short-course aminoglycoside therapy in patients with spinal cord injury. Standard dose versus low dose.
Topics: Adult; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Humans; Injections, Intramuscular; Kanamycin; Proteus Infections; Providencia; Pseudomonas Infections; Random Allocation; Recurrence; Spinal Cord Injuries; Tobramycin; Urinary Bladder, Neurogenic; Urinary Tract Infections | 1980 |
Comparison of standard versus pharmacokinetically adjusted amikacin dosing in granulocytopenic cancer patients.
Topics: Agranulocytosis; Amikacin; Bacterial Infections; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fever; Hearing Loss; Humans; Kanamycin; Kidney; Kinetics; Moxalactam; Neoplasms; Piperacillin; Ticarcillin | 1982 |
Comparative study of the antibacterial activity of amikacin and tobramycin during Pseudomonas pulmonary infection in patients with cystic fibrosis.
Topics: Amikacin; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Kanamycin; Kinetics; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 1982 |
Ocular penetration of amikacin following intramuscular injection.
Topics: Adult; Aged; Amikacin; Aqueous Humor; Bacterial Infections; Eye; Eye Diseases; Female; Humans; Injections, Intramuscular; Kanamycin; Male; Middle Aged | 1983 |
Prospective comparative study of efficacy and toxicity of netilmicin and amikacin.
Topics: Adult; Aged; Amikacin; Bacterial Infections; Clinical Trials as Topic; Drug Resistance, Microbial; Female; Gentamicins; Humans; Kanamycin; Lung Diseases; Male; Middle Aged; Netilmicin; Sepsis; Urinary Tract Infections | 1980 |
Prospective, randomized trial of netilmicin and amikacin, with emphasis on eighth-nerve toxicity.
Topics: Aged; Amikacin; Audiometry, Pure-Tone; Bacterial Infections; Caloric Tests; Clinical Trials as Topic; Creatinine; Female; Gentamicins; Hearing; Humans; Kanamycin; Kidney; Male; Middle Aged; Netilmicin; Random Allocation; Sex Factors; Vestibule, Labyrinth; Vestibulocochlear Nerve | 1980 |
A randomized comparison of cefoxitin with or without amikacin and clindamycin plus amikacin in surgical sepsis.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Cefoxitin; Clindamycin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Kanamycin; Male; Middle Aged; Postoperative Complications; Prospective Studies | 1981 |
The pharmacokinetics and efficacy of an aminoglycoside administered into the cerebral ventricles in neonates: implications for further evaluation of this route of therapy in meningitis.
Topics: Amikacin; Citrobacter; Escherichia coli Infections; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Injections, Intraventricular; Kanamycin; Kinetics; Male; Meningitis; Meningomyelocele; Retrospective Studies | 1981 |
A comparison of the pharmacokinetics of amikacin and gentamicin.
Topics: Adult; Amikacin; Female; Gentamicins; Humans; Kanamycin; Kinetics; Male | 1981 |
Serum pharmacokinetics of antimycobacterial drugs in patients with multidrug-resistant tuberculosis during therapy.
Topics: Adult; Amikacin; Antitubercular Agents; Female; Humans; Kanamycin; Male; Middle Aged; Tuberculosis, Multidrug-Resistant | 1999 |
Aminoglycoside toxicity: daily versus thrice-weekly dosing for treatment of mycobacterial diseases.
Topics: Adult; Aged; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Kanamycin; Kidney; Male; Middle Aged; Mycobacterium Infections; Streptomycin; Tuberculosis; Vestibule, Labyrinth | 2004 |
Adjuvant interferon gamma in patients with drug - resistant pulmonary tuberculosis: a pilot study.
Topics: Adjuvants, Immunologic; Adult; Amikacin; Antitubercular Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; Follow-Up Studies; Humans; Interferon-gamma; Kanamycin; Male; Middle Aged; Mycobacterium tuberculosis; Pilot Projects; Pyrazinamide; Radiography; Recombinant Proteins; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary | 2004 |
788 other study(ies) available for amikacin and kanamycin a
| Article | Year |
|---|---|
Synthesis and antimicrobial and toxicological studies of amino acid and peptide derivatives of kanamycin A and netilmicin.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Gentamicins; Kanamycin; Lysosomes; Molecular Conformation; Netilmicin; Peptides; Phosphatidylcholines; Phospholipases A; Phospholipases A1; Rats; Thermodynamics | 1995 |
Synthesis and biological evaluation of novel (L)-alpha-amino acid methyl ester, heteroalkyl, and aryl substituted 1,4-naphthoquinone derivatives as antifungal and antibacterial agents.
Topics: Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Fungi; Methyl Ethers; Molecular Structure; Naphthoquinones | 2005 |
Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia.
Topics: Aminoglycosides; Anti-Bacterial Agents; Butirosin Sulfate; Drug Resistance, Multiple, Bacterial; Escherichia coli; Gram-Negative Bacterial Infections; Humans; Kanamycin; Kanamycin Kinase; Microbial Sensitivity Tests; Mutation; Neomycin; Stenotrophomonas maltophilia | 2007 |
Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides.
Topics: Aminoglycosides; Anti-Bacterial Agents; Biological Evolution; DNA Transposable Elements; DNA, Bacterial; Drug Resistance, Bacterial; Gene Silencing; Genes, Bacterial; Microbial Sensitivity Tests; Mutagenesis, Insertional; Mutation; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Conjugation, Genetic; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Integrons; Latin America; Molecular Sequence Data; Plasmids | 2007 |
In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan.
Topics: Aminoglycosides; Anti-Bacterial Agents; Capreomycin; Gentamicins; Humans; Microbial Sensitivity Tests; Mycobacterium chelonae; Mycobacterium fortuitum; Nontuberculous Mycobacteria | 2007 |
High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus.
Topics: Anti-Bacterial Agents; Base Sequence; DNA Transposable Elements; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Gentamicins; Hospitals; Humans; Microbial Sensitivity Tests; Polymerase Chain Reaction; Retrospective Studies; Streptococcus | 2007 |
Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Conjugation, Genetic; Conserved Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Genes, rRNA; Methylation; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Norfloxacin; Plasmids; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2007 |
Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital.
Topics: Acinetobacter; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Brazil; Codon, Terminator; Cross Infection; Drug Resistance, Multiple, Bacterial; Gene Transfer, Horizontal; Genes, Bacterial; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Pseudomonas putida; Transcription, Genetic | 2007 |
Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1.
Topics: Anti-Infective Agents; Base Sequence; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae; Gene Expression Regulation, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid | 2007 |
Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides.
Topics: Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Methyltransferases; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Plasmids; Protein Binding; Ribosome Subunits, Small; RNA, Ribosomal, 16S; Sequence Homology, Amino Acid | 2007 |
Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina.
Topics: Alleles; Amino Acid Sequence; Argentina; Bacterial Proteins; Base Sequence; beta-Lactamases; Cross Infection; DNA Transposable Elements; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey.
Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey | 2008 |
Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics.
Topics: Antitubercular Agents; BCG Vaccine; Microbial Sensitivity Tests; Mycobacterium bovis | 2009 |
Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Drug Design; Fungi; Microbial Sensitivity Tests; Naphthoquinones; Nitrogen; Sulfur | 2009 |
AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.
Topics: Acetylation; Acetyltransferases; Aminoglycosides; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2009 |
Identification of the aminoglycoside resistance determinants armA and rmtC among non-Typhi Salmonella isolates from humans in the United States.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Gentamicins; Humans; India; Infant; Kanamycin; Male; Microbial Sensitivity Tests; Molecular Sequence Data; Salmonella; United States | 2009 |
Pentacyclo-undecane derived cyclic tetra-amines: synthesis and evaluation as potent anti-tuberculosis agents.
Topics: Alkanes; Animals; Antitubercular Agents; Cattle; Cell Line; Cell Survival; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Prenylation | 2009 |
Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Carbohydrates; Chemistry, Pharmaceutical; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Sulfides | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
'On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Fungi; Green Chemistry Technology; Microbial Sensitivity Tests; Naphthoquinones; Nitrogen; Sulfur; Water | 2010 |
Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Membrane Permeability; Cells, Cultured; Drug Resistance, Bacterial; Endosomes; Escherichia coli; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Recurrence; Urinary Bladder; Urinary Tract Infections; Urothelium | 2010 |
Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Base Sequence; Canada; Cattle; DNA Primers; Drug Resistance, Bacterial; Female; Genes, Bacterial; Homozygote; In Vitro Techniques; Mastitis, Bovine; Microbial Sensitivity Tests; Nocardia; Nocardia Infections; Point Mutation; RNA, Bacterial; RNA, Ribosomal, 16S | 2010 |
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin | 2010 |
Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26.
Topics: Adhesins, Bacterial; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Humans; Plasmids; Shiga Toxins | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antioxidants; Erythromycin; Escherichia coli; Glutathione; Kanamycin; Microbial Sensitivity Tests; Novobiocin; Spermidine | 2010 |
Synthesis and antibacterial activity study of a novel class of cationic anthraquinone analogs.
Topics: Anthraquinones; Anti-Bacterial Agents; Cations; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization | 2011 |
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
Topics: Antitubercular Agents; Carbohydrates; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxidoreductases; Thiocarbamates; Thioglucosides | 2011 |
Micelles catalyzed chemoselective synthesis 'in water' and biological evaluation of oxygen containing hetero-1,4-naphthoquinones as potential antifungal agents.
Topics: Antifungal Agents; Candida; Catalysis; Drug Evaluation, Preclinical; Micelles; Microbial Sensitivity Tests; Naphthoquinones; Oxygen; Sporothrix; Trichophyton; Water | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Streptomyces; Vero Cells | 2013 |
Synthesis and Biological Activity of Mono- and Di-N-acylated Aminoglycosides.
Topics: | 2015 |
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Multiple, Bacterial; Fungi; Humans; Latent Tuberculosis; Microbial Sensitivity Tests; Microsomes; Mutagens; Mycobacterium tuberculosis; Oxazoles; Primary Cell Culture; Rifampin; Structure-Activity Relationship; Thiadiazoles | 2016 |
Effects of 5-O-Ribosylation of Aminoglycosides on Antimicrobial Activity and Selective Perturbation of Bacterial Translation.
Topics: Aminoglycosides; Anti-Bacterial Agents; Escherichia coli Proteins; Framycetin; Gram-Negative Bacteria; Kanamycin; Microbial Sensitivity Tests; Ribose; Structure-Activity Relationship; Trisaccharides | 2016 |
Synthesis and bioactivity investigation of quinone-based dimeric cationic triazolium amphiphiles selective against resistant fungal and bacterial pathogens.
Topics: Anti-Bacterial Agents; Antifungal Agents; Azoles; Benzoquinones; Cell Line, Tumor; Drug Design; Drug Resistance, Bacterial; Drug Resistance, Fungal; Humans; Sensitivity and Specificity; Surface-Active Agents; Triazoles | 2017 |
Covalently linked kanamycin - Ciprofloxacin hybrid antibiotics as a tool to fight bacterial resistance.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Kanamycin; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2017 |
Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure.
Topics: Anti-Bacterial Agents; Drug Interactions; Molecular Structure | 2017 |
Amphiphilic Tobramycin-Lysine Conjugates Sensitize Multidrug Resistant Gram-Negative Bacteria to Rifampicin and Minocycline.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Hemolysis; Lysine; Microbial Sensitivity Tests; Minocycline; Models, Biological; Rifampin; Tobramycin | 2017 |
Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Coumarins; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Polyketide Synthases; Structure-Activity Relationship; Vero Cells | 2019 |
Design, synthesis and antibacterial activity against pathogenic mycobacteria of conjugated hydroxamic acids, hydrazides and O-alkyl/O-acyl protected hydroxamic derivatives.
Topics: Animals; Anti-Bacterial Agents; Hydrazines; Hydroxamic Acids; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Structure-Activity Relationship | 2022 |
Pharmaceutical properties and stability of amikacin - part I.
Topics: Amikacin; Biological Assay; Drug Stability; Drug Storage; Escherichia coli; Hot Temperature; Hydrogen-Ion Concentration; Kanamycin; Osmolar Concentration; Powders; Sodium; Solubility; Solutions | 1976 |
Physical compatibility and chemical stability of amikacin sulfate in large-volume parenteral solutions - part II.
Topics: Amikacin; Drug Incompatibility; Drug Stability; Drug Storage; Freezing; Hydrogen-Ion Concentration; Injections, Intravenous; Kanamycin; Solutions; Time Factors | 1976 |
Physical compatibility and chemical stability of amikacin sulfate in combination with non-antibiotic drugs in large-volume parenteral solutions - part IV.
Topics: Amikacin; Drug Combinations; Drug Incompatibility; Drug Stability; Hydrogen-Ion Concentration; Injections, Intravenous; Kanamycin; Solutions; Time Factors | 1976 |
The effects of amikacin on autonomic and neuromuscular transmission [proceedings].
Topics: Amikacin; Animals; Autonomic Nervous System; Cats; Chickens; Depression, Chemical; In Vitro Techniques; Kanamycin; Mice; Muscle Contraction; Neuromuscular Junction; Rats; Synaptic Transmission | 1977 |
The pH-dependent influence of aminoglycoside antibiotics on iodohippurate accumulation in rabbit renal cortical slices.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Hydrogen-Ion Concentration; In Vitro Techniques; Iodohippuric Acid; Kanamycin; Kidney Cortex; Rabbits; Streptomycin; Tobramycin | 1978 |
[Neuromuscular inhibition of new aminoglycoside antibiotics].
Topics: Amikacin; Animals; Apnea; Dibekacin; Dose-Response Relationship, Drug; Gentamicins; Kanamycin; Mice; Neuromuscular Blocking Agents; Phrenic Nerve; Sisomicin; Streptomycin | 1979 |
[12th Bristol Symposium. Amikacin: its role in hospital antibiotic therapy. Monte-Carlo, 1-3 March 1979].
Topics: Amikacin; Animals; Bacterial Infections; Congresses as Topic; France; Humans; Kanamycin | 1979 |
Aminoglycoside 6'-N-acetyl-transferase of Pseudomonas aeruginosa: structural requirements of substrate.
Topics: Acetylation; Acetyltransferases; Amikacin; Aminoglycosides; Butirosin Sulfate; Chemical Phenomena; Chemistry; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Neomycin; Pseudomonas aeruginosa; Ribostamycin; Tobramycin | 1975 |
[Mechanisms of inactivation of aminosides. Relationship to phenotype in Gram negative bacilli].
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Butirosin Sulfate; Drug Resistance, Microbial; Enterobacteriaceae; Framycetin; Gentamicins; Kanamycin; Paromomycin; Phenotype; R Factors; Sisomicin; Structure-Activity Relationship; Tobramycin | 1975 |
Amikacin, an aminoglycoside with marked activity against antibiotic-resistant clinical isolates.
Topics: Acinetobacter; Alcaligenes; Amikacin; Bacteria; Butirosin Sulfate; Dibekacin; Drug Resistance, Microbial; Enterobacteriaceae; Flavobacterium; Gentamicins; Kanamycin; Neomycin; Paromomycin; Pseudomonas; Ribostamycin; Staphylococcus; Tobramycin | 1976 |
In vitro activity of amikacin and ten other aminoglycoside antibiotics against gentamicin-resistant bacterial strains.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Butirosin Sulfate; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Kanamycin; Neomycin; Paromomycin; Pseudomonas aeruginosa; Ribostamycin; Sisomicin; Streptomycin; Tobramycin | 1976 |
[Side effects of aminoglycosides: nephrotoxicity (author's transl)].
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Aspartate Aminotransferases; Butirosin Sulfate; Creatinine; Dose-Response Relationship, Drug; Female; Gentamicins; Guinea Pigs; Humans; Kanamycin; Kidney Tubules; L-Lactate Dehydrogenase; Rats; Sisomicin; Tobramycin | 1976 |
Amikacin resistance developing in patients with Pseudomonas aeruginosa bronchopneumonia.
Topics: Amikacin; Bronchopneumonia; Drug Resistance, Microbial; Female; Humans; Kanamycin; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections | 1977 |
Effect of combinations of penicillin and aminoglycosides on Streptococcus faecalis: a comparative study of seven aminoglycoside antibiotics.
Topics: Amikacin; Aminoglycosides; Butirosin Sulfate; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecalis; Gentamicins; Humans; Kanamycin; Penicillin Resistance; Penicillins; Sisomicin; Streptomycin | 1977 |
Amikacin.
Topics: Amikacin; Bacterial Infections; Drug Evaluation; Gentamicins; Humans; Kanamycin | 1977 |
Klebsiella meningitis treated with intrathecal amikacin.
Topics: Adult; Amikacin; Carbenicillin; Humans; Injections, Intravenous; Injections, Spinal; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Male; Meningitis | 1977 |
[Comparative studies on the problem of nephrotoxicity of the aminoglycosides: kanamycin, amikacin, butirosin and kanendomycin].
Topics: Amikacin; Animals; Anti-Bacterial Agents; Butirosin Sulfate; Female; Kanamycin; Kidney Diseases; Rats | 1976 |
Amikacin.
Topics: Amikacin; Bacterial Infections; Biological Availability; Gentamicins; Humans; Kanamycin | 1977 |
Amikacin.
Topics: Acetyltransferases; Amikacin; Bacteria; Drug Resistance, Microbial; Gentamicins; Kanamycin | 1975 |
[Spectrophotometric and chromatographic studies of amikacin and butyrosine].
Topics: Amikacin; Anti-Bacterial Agents; Butirosin Sulfate; Chromatography, Thin Layer; Colorimetry; Kanamycin | 1978 |
Activity of amikacin against Mycobacterium tuberculosis.
Topics: Amikacin; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis | 1978 |
In vitro antibacterial activity of amikacin and ticarcillin, alone and in combination, against Pseudomonas aerurginosa.
Topics: Amikacin; Drug Interactions; Kanamycin; Microbial Sensitivity Tests; Penicillins; Pseudomonas aeruginosa; Ticarcillin | 1978 |
UK-18892, a new aminoglycoside: an in vitro study.
Topics: Acetylation; Amikacin; Blood Proteins; Enterobacteriaceae; Gentamicins; Humans; In Vitro Techniques; Kanamycin; Microbial Sensitivity Tests; Protein Binding; Pseudomonas aeruginosa; Staphylococcus aureus | 1978 |
Therapeutic effect of topical antibiotic on untreated eye in experimental keratitis.
Topics: Absorption; Administration, Topical; Amikacin; Animals; Anti-Bacterial Agents; Biological Availability; Cornea; Drug Evaluation, Preclinical; Guinea Pigs; Kanamycin; Keratitis; Male; Ophthalmic Solutions; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors; Tobramycin | 1978 |
Amikacin and netilmicin resistance in Pseudomonas aeruginosa: incidence and transfer.
Topics: Amikacin; Drug Resistance, Microbial; Gentamicins; Kanamycin; Lysogeny; Microbial Sensitivity Tests; Netilmicin; Pseudomonas aeruginosa; Sisomicin; Tobramycin | 1979 |
[Effect of amikacin on experimental tuberculosis of mice (author's transl)].
Topics: Amikacin; Animals; Kanamycin; Male; Mice; Mycobacterium tuberculosis; Tuberculosis | 1979 |
[Antibacterial activity of gentamicin, tobramycin, amikacin, and sisomicin in vitro (author's transl)].
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Gentamicins; Kanamycin; Proteus mirabilis; Pseudomonas aeruginosa; Sisomicin; Staphylococcus aureus; Tobramycin | 1978 |
[Treatment of Pseudomonas aeruginosa pneumonia with amikacin (author's transl)].
Topics: Adult; Amikacin; Female; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections | 1979 |
[Comparison of bactericidal effects of four aminoglycoside antibiotics: amikacin, gentamicin, kanamycin and tobramycin (author's transl)].
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Escherichia coli; Gentamicins; Kanamycin; Kinetics; Klebsiella; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Serratia; Tobramycin | 1979 |
[Effect of combination of hetacillin, cephapirin and amikacin (author's transl)].
Topics: Amikacin; Bacteria; Cephalosporins; Cephapirin; Drug Combinations; Drug Synergism; Escherichia coli; Kanamycin; Klebsiella pneumoniae; Penicillin Resistance; Penicillins; Proteus mirabilis; Pseudomonas aeruginosa; Staphylococcus | 1979 |
Global and effective synergism of amikacin, gentamicin or tobramycin when combined with carbenicillin against Pseudomonas aeruginosa.
Topics: Amikacin; Anti-Bacterial Agents; Carbenicillin; Drug Synergism; Gentamicins; Kanamycin; Pseudomonas aeruginosa; Tobramycin | 1979 |
A broth-disc technique for the assay of antibiotic synergism.
Topics: Amikacin; Anti-Bacterial Agents; Carbenicillin; Drug Synergism; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Streptococcus; Tobramycin | 1979 |
[Antibacterial activity of amikacin towards gentamicin-resistant, Gram-negative bacilli].
Topics: Amikacin; Drug Resistance, Microbial; Escherichia coli; Gentamicins; Kanamycin; Klebsiella; Microbial Sensitivity Tests; Proteus; Pseudomonas aeruginosa; Serratia; Sisomicin; Tobramycin | 1979 |
[Animal experiments concerning the neurotoxicity of aminoglycosid antibiotics. Electron microscopic findings regarding dose--depending mitochondrial damage in the cochlear nucleus of the guinea pig (author's transl)].
Topics: Amikacin; Animals; Anti-Bacterial Agents; Cochlear Nerve; Gentamicins; Guinea Pigs; Kanamycin; Mitochondria; Nerve Degeneration; Tobramycin | 1976 |
Physical compatibility and chemical stability of amikacin sulfate in combination with antibiotics in large-volume parenteral solutions - part III.
Topics: Amikacin; Amphotericin B; Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Drug Combinations; Drug Incompatibility; Drug Stability; Erythromycin; Injections, Intravenous; Kanamycin; Lincomycin; Novobiocin; Penicillins; Polymyxins; Solutions; Tetracyclines; Time Factors; Vancomycin | 1976 |
Some effects of the aminoglycoside antibiotic amikacin on neuromuscular and autonomic transmission.
Topics: Amikacin; Animals; Autonomic Nervous System; Calcium; Cats; Chickens; Drug Interactions; Female; In Vitro Techniques; Kanamycin; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Motor Endplate; Neuromuscular Junction; Rats; Synaptic Transmission; Tubocurarine | 1978 |
[Comparison of the antibacterial activity of amikacin (BB-K8) with other aminoglycosides against pathogens recently isolated from clinical materials (author's transl) ].
Topics: Amikacin; Enterobacteriaceae; Escherichia coli; Gentamicins; Kanamycin; Klebsiella; Proteus; Pseudomonas aeruginosa; Serratia; Staphylococcus; Streptococcus; Streptococcus pneumoniae; Tobramycin | 1975 |
[Pharmacokinetics of lividomycin, aminkacin and sisomicin in patients with chronic renal insufficiency].
Topics: Amikacin; Gentamicins; Humans; Kanamycin; Kidney Failure, Chronic; Kinetics; Paromomycin; Sisomicin | 1977 |
In vitro susceptibility of pseudomonas to four beta-lactamantibiotics (ampicillin, cephalothin, carbenicillin, piperacillin), to four aminoglycosides (kanamycin, amikacin, gentamicin, tobramycin) and to colimycin.
Topics: Amikacin; Aminoglycosides; Ampicillin; Carbenicillin; Cephalothin; Child; Colistin; Cystic Fibrosis; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pseudomonas; Sputum; Tobramycin | 1979 |
Aminoglycoside antibiotics moderately impair granulocyte function.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Chemotaxis, Leukocyte; Gentamicins; Granulocytes; Kanamycin; Netilmicin; Phagocytosis; Tobramycin | 1978 |
Comparative study of Amikacin (BB-K8) and gentamicin activity in vitro against Proteus rettgeri.
Topics: Amikacin; Animals; Drug Evaluation; Drug Resistance, Microbial; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Proteus | 1977 |
[Intravenous administration of amikacin sulfate for the infections complicated with hematologic disorders (author's transl)].
Topics: Adolescent; Adult; Amikacin; Anemia, Aplastic; Female; Hematologic Diseases; Humans; Infections; Injections, Intravenous; Kanamycin; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Middle Aged; Pneumonia; Sepsis | 1977 |
Gentamicin and amikacin---an in vitro comparison using 1000 clinical isolates.
Topics: Amikacin; Bacteria; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Haemophilus; Humans; Kanamycin; Klebsiella; Microbial Sensitivity Tests; Providencia; Pseudomonas; Staphylococcus; Streptococcus | 1978 |
[Experience in combination therapy with amikacin, mainly by intravenous drip infusion of a large dose, for infections in acute leukaemia patients (author's transl)].
Topics: Adult; Aged; Amikacin; Bacterial Infections; Cephacetrile; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Kanamycin; Leukemia, Myeloid, Acute; Male; Middle Aged; Pneumonia; Sulbenicillin | 1979 |
[Amikacin in the treatment of febrile complications occurring during the neutropenic phase of acute hemopathies].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Female; Fever; Humans; Kanamycin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia | 1979 |
Comparison of four aminoglycoside antibiotics in the therapy of experimental E. coli meningitis.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Escherichia coli; Escherichia coli Infections; Gentamicins; Kanamycin; Meningitis; Rabbits; Sisomicin; Tobramycin | 1977 |
Amikacin therapy of patients with multiply antibiotic-resistant Serratia marcescens infections: development of increasing resistance during therapy.
Topics: Adult; Aged; Amikacin; Cross Infection; Disease Outbreaks; Drug Resistance, Microbial; Enterobacteriaceae Infections; Female; Humans; Kanamycin; Male; Middle Aged; Serratia marcescens; Urinary Tract Infections | 1977 |
Clinical experience with amikacin, a new aminoglycoside antibiotic.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Enterobacteriaceae Infections; Female; Humans; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Lung Diseases; Male; Middle Aged; Pseudomonas Infections | 1977 |
Amikacin therapy. Use against infections caused by gentamicin- and tobramycin-resistant organisms.
Topics: Adult; Aged; Amikacin; Bacterial Infections; Child, Preschool; Drug Evaluation; Drug Resistance, Microbial; Ear; Gentamicins; Humans; Kanamycin; Middle Aged; Pseudomonas; Sepsis; Serratia marcescens; Tobramycin | 1977 |
Experience with amikacin and colistin in an outbreak of infection by resistant Klebsiella aerogenes.
Topics: Aged; Amikacin; Colistin; Cross Infection; Disease Outbreaks; Drug Administration Schedule; Drug Resistance, Microbial; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Urinary Tract Infections | 1977 |
Inhibition of acetylating activity in an enzymatic assay for aminoglycoside antibiotics.
Topics: Acetylation; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteriological Techniques; Gentamicins; In Vitro Techniques; Kanamycin; Tobramycin | 1977 |
Amikacin and cephalothin: empiric regimen for granulocytopenic cancer patients.
Topics: Adult; Agranulocytosis; Amikacin; Cephalothin; Drug Therapy, Combination; Escherichia coli Infections; Female; Humans; Kanamycin; Male; Neoplasms; Pseudomonas Infections | 1977 |
In vitro susceptibility of Nocardia asteroides to amikacin.
Topics: Amikacin; In Vitro Techniques; Kanamycin; Nocardia asteroides | 1978 |
The comparative synergistic activity of amikacin, gentamicin, netilmicin and azlocillin, mezlocillin, carbenicillin and ticarcillin against Serratia marcescens.
Topics: Amikacin; Carbenicillin; Drug Synergism; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Penicillins; Serratia marcescens; Sisomicin; Ticarcillin; Time Factors | 1978 |
Amikacin therapy of gram-negative bacteremia and meningitis. Treatment in diseases due to multiple resistant bacilli.
Topics: Adolescent; Adult; Aged; Amikacin; Cross Infection; Drug Resistance, Microbial; Enterobacteriaceae Infections; Escherichia coli Infections; Humans; Kanamycin; Klebsiella Infections; Meningitis; Proteus Infections; Sepsis; Serratia marcescens | 1978 |
Rapid development of resistance of gentamicin, tobramycin and amikacin by E. coli 07..
Topics: Adult; Amikacin; Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Gentamicins; Humans; Kanamycin; Male; Tobramycin | 1978 |
Amikacin in gram-negative paediatric infections.
Topics: Adolescent; Amikacin; Bacterial Infections; Child; Child, Preschool; Escherichia coli Infections; Female; Gastrointestinal Diseases; Humans; Infant; Infant, Newborn; Kanamycin; Klebsiella Infections; Male; Respiratory Tract Infections; Skin Diseases; Urinary Tract Infections | 1978 |
Amikacin in the treatment of genito-urinary tract infections in cancer patients.
Topics: Adult; Aged; Amikacin; Cystitis; Escherichia coli Infections; Female; Humans; Kanamycin; Male; Middle Aged; Pseudomonas Infections; Pyelonephritis; Urinary Bladder Neoplasms | 1978 |
Intraventricular administration of amikacin for complicated Gram-negative meningitis and ventriculitis.
Topics: Acinetobacter Infections; Amikacin; Child, Preschool; Encephalitis; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Humans; Infant; Infant, Newborn; Injections, Intraventricular; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Male; Meningitis; Serratia marcescens | 1979 |
Amikacin assay in serum by high-performance liquid chromatography.
Topics: Amikacin; Chromatography, Liquid; Kanamycin; Microbiological Techniques | 1978 |
Nonspecific aminoglycoside cross-resistance of Serratia marcescens.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Microbial; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Neomycin; Netilmicin; Phenotype; Serratia marcescens; Sisomicin; Streptomycin | 1979 |
[Bactericidal kinetics of cefazolin, cefoxitin and amikacin alone and in combination (author's transl)].
Topics: Amikacin; Bacteria; Bacterial Infections; Cefazolin; Cefoxitin; Cephalosporins; Drug Synergism; Escherichia coli; Humans; Kanamycin; Klebsiella pneumoniae; Microbial Sensitivity Tests; Proteus vulgaris; Time Factors | 1978 |
Treatment of experimental nocardiosis in mice: comparison of amikacin and sulfonamide.
Topics: Amikacin; Animals; Chronic Disease; Kanamycin; Mice; Mice, Inbred BALB C; Nocardia asteroides; Nocardia Infections; Sulfonamides | 1979 |
Activity of cefuroxime, cefoxitin and amikacin against Serratia marcesens.
Topics: Amikacin; Cefoxitin; Cefuroxime; Cephalosporins; Kanamycin; Microbial Sensitivity Tests; Serratia marcescens | 1979 |
In vitro activity of cefamandole, cefoxitin, cefuroxime, and carbenicillin, alone and in combination with aminoglycosides against Serratia marcescens.
Topics: Amikacin; Aminoglycosides; Carbenicillin; Cefamandole; Cefoxitin; Cefuroxime; Cephalosporins; Drug Synergism; Drug Therapy, Combination; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Serratia marcescens; Tobramycin | 1979 |
Amikacin resistance associated with a plasmid-borne aminoglycoside phosphotransferase in Escherichia coli.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Microbial Sensitivity Tests; Mutation; Phosphotransferases; R Factors | 1979 |
Klebsiella pneumoniae: in vitro antibacterial activity of cefoxitin and amikacin, alone and in combination.
Topics: Amikacin; Cefoxitin; Drug Interactions; Kanamycin; Klebsiella pneumoniae; Microbial Sensitivity Tests | 1979 |
[Bactericidal activity of aminosides in a static system and in a dynamic model].
Topics: Amikacin; Aminoglycosides; Escherichia coli; Gentamicins; Kanamycin; Klebsiella; Methods; Microbial Sensitivity Tests; Pseudomonas; Serratia; Tobramycin | 1979 |
Comparative clinical pharmacology of amikacin and kanamycin in dairy calves.
Topics: Amikacin; Animals; Cattle; Escherichia coli; Kanamycin; Pseudomonas aeruginosa; Salmonella | 1977 |
Sensitivity of gram-negative bacteria to six aminoglycoside antibiotics.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Gentamicins; Gram-Negative Aerobic Bacteria; Gram-Negative Anaerobic Bacteria; Humans; Kanamycin; Klebsiella; Proteus mirabilis; Pseudomonas aeruginosa; Sisomicin; Tobramycin | 1977 |
[Fundamental and clinical studies on amikacin (BB-K8) in complicated urinary tract infections (author's transl)].
Topics: Adult; Aged; Amikacin; Drug Evaluation; Drug Resistance, Microbial; Female; Humans; Kanamycin; Male; Middle Aged; Pseudomonas aeruginosa; Serratia marcescens; Urinary Tract Infections | 1977 |
Bactericidal activity of amikacin and gentamicin.
Topics: Amikacin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gentamicins; Kanamycin; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1977 |
In vitro anti-mycobacterial activity of some new amino-glycoside antibiotics.
Topics: Amikacin; Gentamicins; Kanamycin; Mycobacterium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Sisomicin; Tobramycin | 1977 |
Amikacin therapy of exacerbations of Pseudomonas aeruginosa infections in patients with cystic fibrosis.
Topics: Acute Disease; Adolescent; Adult; Amikacin; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Kanamycin; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections | 1977 |
Patterns and mechanisms of emergence of resistance to amikacin.
Topics: Aged; Amikacin; Drug Resistance, Microbial; Humans; Kanamycin; Klebsiella pneumoniae; Male; Middle Aged; Proteus; Pseudomonas aeruginosa; Serratia marcescens | 1977 |
Synergistic activity of trimethoprim and amikacin against gram-negative bacilli.
Topics: Amikacin; Drug Synergism; Escherichia coli; Kanamycin; Klebsiella pneumoniae; Pseudomonas aeruginosa; Serratia marcescens; Species Specificity; Trimethoprim | 1977 |
Emergence in a burn center of populations of bacteria resistant to gentamicin, tobramycin, and amikacin: evidence for the need for changes in zone diameter interpretative standards.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Burns; Drug Resistance, Microbial; Escherichia coli; Gentamicins; Kanamycin; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin | 1977 |
Effect of cation content of agar on the activity of gentamicin, tobramycin, and amikacin against Pseudomonas aeruginosa.
Topics: Agar; Amikacin; Anti-Bacterial Agents; Calcium; Depression, Chemical; Drug Synergism; Gentamicins; Kanamycin; Magnesium; Pseudomonas aeruginosa; Tobramycin | 1978 |
Gentamicin-resistant bacillary infection. Clinical features and amikacin therapy.
Topics: Adult; Aged; Amikacin; Bacterial Infections; Cross Infection; Drug Resistance, Microbial; Enterobacteriaceae Infections; Female; Gentamicins; Humans; In Vitro Techniques; Infant; Kanamycin; Male; Middle Aged; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Serratia marcescens; Urinary Tract Infections | 1978 |
Amikacin concentration in the cerebrospinal fluid of children with acute bacterial meningitis.
Topics: Acute Disease; Amikacin; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Kanamycin; Kinetics; Male; Meningitis | 1979 |
Empiric therapy for infections in granulocytopenic cancer patients: continuous infusion of amikacin plus cephalothin.
Topics: Acute Disease; Amikacin; Bacterial Infections; Cephalothin; Drug Therapy, Combination; Gram-Negative Aerobic Bacteria; Gram-Negative Anaerobic Bacteria; Hodgkin Disease; Humans; Infusions, Parenteral; Kanamycin; Leukemia | 1979 |
Abnormal neutrophil chemotaxis and random migration induced by aminoglycoside antibiotics.
Topics: Adult; Amikacin; Aminoglycosides; Cell Movement; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Female; Gentamicins; Humans; Infusions, Parenteral; Kanamycin; Leukocytes; Male; Time Factors | 1979 |
Antibiotic level by radioimmunoassay: part one-amikacin.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Child; Child, Preschool; Female; Humans; Infant; Kanamycin; Male; Middle Aged; Radioimmunoassay | 1979 |
The effect of topical application of antibiotics on the cerebral cortex: an experimental update.
Topics: Administration, Topical; Amikacin; Animals; Anti-Bacterial Agents; Carbenicillin; Cats; Cephalothin; Cerebral Cortex; Electroencephalography; Gentamicins; Kanamycin; Methicillin; Neomycin; Penicillins; Seizures; Time Factors; Tobramycin | 1979 |
Pharmacokinetics of amikacin in infants and pre-school children.
Topics: Age Factors; Amikacin; Bacterial Infections; Body Weight; Child; Child, Preschool; Female; Half-Life; Humans; Infant; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Male; Time Factors | 1979 |
Pharmacokinetics of Amikacin (BB-K8) in patients with normal or impaired renal function.
Topics: Adolescent; Adult; Aged; Amikacin; Female; Half-Life; Humans; Kanamycin; Kidney Diseases; Kidney Function Tests; Kinetics; Male; Middle Aged; Models, Biological | 1979 |
Laboratory evaluation of amikacin susceptibility testing by the AutoBac I system.
Topics: Amikacin; Bacteria; Bacterial Infections; Drug Resistance, Microbial; Humans; Kanamycin; Microbial Sensitivity Tests; Species Specificity | 1979 |
[Current drugs. Amikacin].
Topics: Amikacin; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Half-Life; Humans; Kanamycin | 1979 |
Massive amikacin "overdose".
Topics: Acute Disease; Amikacin; Female; Humans; Injections, Intravenous; Kanamycin; Kidney; Medication Errors; Middle Aged; Renal Dialysis | 1979 |
Interpretation of the disk diffusion susceptibility test for amikacin: report of a collaborative study.
Topics: Amikacin; Bacteria; Kanamycin; Methods; Microbial Sensitivity Tests | 1979 |
Pharmacokinetics of intravenous amikacin after rapid and slow infusion with special reference to hemodialysis.
Topics: Adult; Amikacin; Biotransformation; Female; Half-Life; Humans; Infusions, Parenteral; Injections, Intravenous; Kanamycin; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Renal Dialysis; Time Factors | 1979 |
13C-NMR studies on 1-N-[(S)-4-amino-2-hydroxybutyl]kanamycin A (butikacin) and related aminoglycosides.
Topics: Alkylation; Amikacin; Chemical Phenomena; Chemistry; Kanamycin; Magnetic Resonance Spectroscopy | 1979 |
Aminoglycoside antibiotics. XIII. Synthesis and activity of 4-deoxy-6'-n-methylamikacin and related compounds.
Topics: Amikacin; Chemical Phenomena; Chemistry; Kanamycin; Methylation; Microbial Sensitivity Tests; Oxidation-Reduction; Structure-Activity Relationship | 1979 |
[Clinical evaluation of amikacin for respiratory infections (author's transl)].
Topics: Adult; Aged; Amikacin; Female; Humans; Kanamycin; Male; Middle Aged; Pleural Effusion; Respiratory Tract Infections | 1979 |
[Treatment of hospital-acquired urinary infections with amikacin (author's transl)].
Topics: Amikacin; Cross Infection; Drug Evaluation; Drug Resistance, Microbial; Female; Hearing Disorders; Humans; Kanamycin; Male; Middle Aged; Urinary Tract Infections | 1979 |
Spectrophotometric assay for amikacin using purified kanamycin acetyltransferase.
Topics: Acetyltransferases; Amikacin; Kanamycin; Methods; Spectrophotometry | 1979 |
Pharmacokinetics of amikacin (BB-K8) in patients undergoing hemodialysis.
Topics: Adult; Amikacin; Female; Humans; Kanamycin; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Renal Dialysis; Time Factors | 1979 |
Synergism between amikacin and cefazolin against Staphylococcus aureus: a comparative study of oxacillin-sensitive and oxacillin-resistant strains.
Topics: Amikacin; Cefazolin; Drug Synergism; Humans; Kanamycin; Male; Oxacillin; Penicillin Resistance; Staphylococcus aureus; Time Factors | 1979 |
Aminoglycoside use monitored by clinical pharmaceutical services.
Topics: Amikacin; Anti-Bacterial Agents; California; Drug Utilization; Hospital Departments; Hospitals, University; Humans; Infections; Kanamycin; Pharmacy Service, Hospital; Tobramycin; Utilization Review | 1979 |
Multiple-dose amikacin kinetics in pediatric oncology patients.
Topics: Adolescent; Amikacin; Child; Child, Preschool; Drug Administration Schedule; Humans; Infant; Kanamycin; Kinetics; Mathematics; Neoplasms | 1979 |
Amikacin dosage in the preterm newborn.
Topics: Amikacin; Bacterial Infections; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Male; Radioimmunoassay | 1979 |
The susceptibility of recently isolates of gram-negative bacteria to amikacin and other aminoglycosides.
Topics: Amikacin; Aminoglycosides; Bacteria; Kanamycin; Microbial Sensitivity Tests | 1979 |
Cochlear toxicity of butikacin (UK-18,892), a new semisynthetic aminoglycoside antibiotic, in guinea pigs.
Topics: Amikacin; Animals; Auditory Threshold; Cochlea; Female; Guinea Pigs; Hearing Disorders; Kanamycin; Labyrinth Diseases; Male; Time Factors | 1979 |
Accidental amikacin overdose in man: emergency therapy by extrarenal dialysis.
Topics: Accidents; Adult; Aged; Amikacin; Child; Emergencies; Humans; Kanamycin; Poisoning; Renal Dialysis | 1979 |
Amikacin: in vitro bacteriological studies, levels in human serum, lung and heart tissue, and clinical results.
Topics: Amikacin; Bacteria; Bacterial Infections; Drug Resistance, Microbial; Female; Gentamicins; Humans; Kanamycin; Lung; Male; Myocardium | 1979 |
Behavior of amikacin in renal parenchyma of normal rats and of rats with acute obstructive renal insufficiency.
Topics: Amikacin; Animals; Half-Life; Kanamycin; Kidney Cortex; Kidney Diseases; Kinetics; Rats | 1979 |
[Clinical and laboratory evaluation of amikacin].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Child; Child, Preschool; Drug Evaluation; Female; Humans; Infant; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged | 1979 |
Comparative nephrotoxicity of SCH 21420 and amikacin in rats.
Topics: Amikacin; Animals; Creatinine; Enzymes; Gentamicins; Kanamycin; Kidney Diseases; Male; Proteinuria; Rats; Time Factors | 1979 |
Bronchial secretion levels of amikacin.
Topics: Aged; Amikacin; Bronchi; Half-Life; Humans; Kanamycin; Male; Middle Aged; Time Factors | 1979 |
Fortimicin A: collaborative in vitro susceptibility. Comparison with amikacin and gentamicin against 11,840 clinical bacterial isolates.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Staphylococcus; Streptococcus | 1979 |
Amikacin pharmacokinetics in pediatric patients with malignancy.
Topics: Adolescent; Amikacin; Bacterial Infections; Blood Urea Nitrogen; Child; Child, Preschool; Creatinine; Female; Half-Life; Humans; Infant; Infusions, Parenteral; Kanamycin; Kinetics; Male; Neoplasms | 1979 |
[Enterobacteria isolated in hospitals. Comparison of the bacteriostatic and bactericidal activity of amikacin, gentamicin and tobramycin].
Topics: Amikacin; Anti-Bacterial Agents; Cross Infection; Enterobacteriaceae; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Species Specificity; Tobramycin | 1979 |
[Phenotypes of resistance to aminosides and sensitivity of amikacin in hospitals].
Topics: Amikacin; Aminoglycosides; Cross Infection; Drug Resistance, Microbial; Enterobacteriaceae; Gram-Negative Anaerobic Bacteria; Humans; Kanamycin; Phenotype; Species Specificity; Staphylococcus aureus | 1979 |
[Comparative pharmacokinetics of amikacin after intravenous, intramuscular and subcutaneous administration].
Topics: Adult; Amikacin; Humans; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Kanamycin; Kinetics; Middle Aged | 1979 |
[Pharmacokinetics of amikacin in subjects with normal renal function, in chronic renal failure and during hemodialysis].
Topics: Adult; Amikacin; Half-Life; Humans; Kanamycin; Kidney; Kidney Failure, Chronic; Kinetics; Renal Dialysis | 1979 |
[Peritoneal dialysis and amikacin].
Topics: Acute Kidney Injury; Amikacin; Humans; Kanamycin; Kidney Failure, Chronic; Kinetics; Peritoneal Dialysis | 1979 |
[Peritoneal transfer of amikacin: its use in peritoneal dialysis. Preliminary study].
Topics: Aged; Amikacin; Biological Transport; Female; Humans; Kanamycin; Kinetics; Male; Middle Aged; Peritoneal Dialysis | 1979 |
[Pharmacokinetics of amikacin in bronchial secretions].
Topics: Adult; Aged; Amikacin; Humans; Injections, Intramuscular; Kanamycin; Kinetics; Lung; Middle Aged | 1979 |
[Renal toxicity of amikacin].
Topics: Amikacin; Aminoglycosides; Animals; Humans; Kanamycin; Kidney; Rats | 1979 |
[Auditory tolerance of amikacin. 223 observations].
Topics: Adult; Aged; Amikacin; Drug Tolerance; Ear, Inner; Female; Humans; Kanamycin; Male; Middle Aged | 1979 |
[Serum levels in the surveillance of treatment with amikacin in urology].
Topics: Amikacin; Humans; Kanamycin; Kinetics; Urinary Tract Infections | 1979 |
[Amikacin in reanimation during acute anuric kidney failure].
Topics: Acute Kidney Injury; Adult; Aged; Amikacin; Enuresis; Humans; Kanamycin; Kinetics; Middle Aged; Renal Dialysis | 1979 |
[Pharmacokinetics, bacteriologic and clinical study of amikacin in chronic respiratory failure].
Topics: Amikacin; Chronic Disease; Humans; Kanamycin; Respiratory Insufficiency | 1979 |
[Treatment of febrile episodes in the neutropenic subject: use of the combination of amikacin-colistin-trimethoprim-sulphamethoxazole].
Topics: Agranulocytosis; Amikacin; Colistin; Drug Therapy, Combination; Fever; Humans; Kanamycin; Neutropenia; Sulfamethoxazole; Trimethoprim | 1979 |
[Our experience with amikacin in gastrointestinal surgery].
Topics: Amikacin; Bacterial Infections; Digestive System Surgical Procedures; Humans; Kanamycin; Microbial Sensitivity Tests; Postoperative Complications | 1979 |
[Amikacin in oncologic pelvic surgery].
Topics: Amikacin; Bacterial Infections; Female; Humans; Kanamycin; Male; Middle Aged; Postoperative Complications; Rectal Neoplasms; Urologic Neoplasms; Uterine Neoplasms | 1979 |
[Clinical and pharmacokinetic study of amikacin in pediatrics].
Topics: Amikacin; Child; Cross Infection; Humans; Kanamycin; Microbial Sensitivity Tests; Pediatrics | 1979 |
[Amikacin in the child: efficacy, tolerance, effects on the intestinal microbial ecosystem].
Topics: Amikacin; Bacterial Infections; Child; Child, Preschool; Drug Tolerance; Humans; Infant; Infant, Newborn; Intestines; Kanamycin; Microbial Sensitivity Tests | 1979 |
[Amikacin, in association, in severe infections due to Gram-negative bacteria].
Topics: Adult; Aged; Amikacin; Cross Infection; Drug Tolerance; Female; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Postoperative Complications | 1979 |
[Use of amikacin in a clinic for infectious diseases].
Topics: Amikacin; Communicable Diseases; Humans; Kanamycin | 1979 |
[Effect of infusion of amino acids on the renal elimination of amikacin].
Topics: Amikacin; Amino Acids; Humans; Infusions, Parenteral; Kanamycin; Kinetics | 1979 |
[Pharmacokinetics of amikacin in burn patients (preliminary results)].
Topics: Adolescent; Adult; Amikacin; Burns; Humans; Kanamycin; Kinetics; Middle Aged | 1979 |
[Clinical and pharmacokinetic study of amikacin in septicemia complicating major burns].
Topics: Adolescent; Adult; Aged; Amikacin; Burns; Humans; Kanamycin; Kinetics; Microbial Sensitivity Tests; Middle Aged; Sepsis | 1979 |
[Value of measurement of amikacin levels in the management of antibiotic therapy in intensive care (71 estimations)].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Child; Creatinine; Critical Care; Female; Humans; Kanamycin; Kinetics; Male; Middle Aged | 1979 |
[Amikacin in the treatment of Gram negative bacilli septicemias].
Topics: Amikacin; Critical Care; Enterobacteriaceae; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Sepsis; Tobramycin | 1979 |
[The neuromuscular blocking property of amikacin (author's transl)].
Topics: Adult; Amikacin; Animals; Calcium; Dose-Response Relationship, Drug; Drug Evaluation; Drug Synergism; Edrophonium; Humans; In Vitro Techniques; Kanamycin; Neuromuscular Blocking Agents; Rabbits; Succinylcholine; Tubocurarine | 1977 |
Amikacin therapy for serious gram-negative infection.
Topics: Adult; Aged; Amikacin; Bacterial Infections; Enterobacteriaceae; Enterobacteriaceae Infections; Gentamicins; Humans; Kanamycin; Kidney; Klebsiella Infections; Middle Aged; Pseudomonas Infections; Sepsis | 1977 |
Evaluation of amikacin sulfate (Amikin). A new aminoglycoside antibiotic.
Topics: Amikacin; Bacteria; Bacterial Infections; Drug Evaluation; Drug Resistance, Microbial; Drug Synergism; Humans; Immunosuppression Therapy; Kanamycin | 1977 |
[Pharmacokinetical, histological, and histochemical investigation on the ototoxicity of gentamicin, tobramycin, and amikacin (author's transl)].
Topics: Amikacin; Animals; Anti-Bacterial Agents; Cochlea; Ear, Inner; Endolymph; Gentamicins; Guinea Pigs; Kanamycin; Tobramycin | 1977 |
[Amikacin and kanamycin. Comparative experimental studies on nephrotoxicity].
Topics: Amikacin; Animals; Blood Urea Nitrogen; Enzymes; Female; Glycosuria; Kanamycin; Kidney Diseases; Proteinuria; Rats; Time Factors | 1978 |
[Dibekacin--a novel aminoglycoside antibioticl. Antimicrobial activity and parallel resistance in vitro].
Topics: Amikacin; Bacteria; Dibekacin; Drug Resistance, Microbial; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Sisomicin; Tobramycin | 1979 |
[Experimental studies on topic application of amikacin to the eye (author's transl)].
Topics: Administration, Topical; Amikacin; Animals; Aqueous Humor; Conjunctiva; Cornea; Eye; Injections; Kanamycin; Ophthalmic Solutions; Rabbits | 1978 |
[Amikacin in lumbar and ventricular cerebrospinal fluid: Concentrations after intramuscular or intrathecal injection. Study of 16 patients. Therapeutic implications].
Topics: Adolescent; Adult; Aged; Amikacin; Child; Child, Preschool; Humans; Injections, Intramuscular; Injections, Spinal; Kanamycin; Kinetics; Middle Aged | 1979 |
3'-Deoxyamikacin and 3',4'-dideoxyamikacin and their antibacterial activities.
Topics: Amikacin; Bacteria; Bacterial Infections; Humans; Kanamycin; Microbial Sensitivity Tests | 1979 |
Synthesis and antibacterial activities of 1-N [(S)-omega-amino-2-hydroxyalkyl] kanamycin A derivatives.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Resistance, Microbial; Female; Kanamycin; Mice; Microbial Sensitivity Tests | 1977 |
Frequency of resistance to kanamycin, tobramycin, netilmicin, and amikacin in gentamicin-resistant gram-negative bacteria.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Gentamicins; Kanamycin; Sisomicin; Tobramycin | 1978 |
Amikacin sulfate.
Topics: Amikacin; Bacteria; Drug Resistance, Microbial; Kanamycin; United States | 1978 |
In vitro susceptiiblity of Mycobacterium fortuitum and Mycobacterium chelonei to amikacin.
Topics: Amikacin; Kanamycin; Microbial Sensitivity Tests; Mycobacterium; Species Specificity | 1978 |
[Therapeutic effect of amikacin for infections with gram-negative bacilli, especially for stubborn respiratory infections (author's transl)].
Topics: Adult; Aged; Amikacin; Bronchiectasis; Chronic Disease; Drug Evaluation; Empyema; Female; Humans; Kanamycin; Lung Neoplasms; Male; Middle Aged; Pneumonia; Respiratory Tract Infections; Tuberculosis, Pulmonary; Urinary Tract Infections | 1978 |
Problems in diagnosis and therapy of Mycobacterium fortuitum infections.
Topics: Adolescent; Adult; Amikacin; Doxycycline; Female; Humans; Kanamycin; Lymphadenitis; Male; Meningitis; Middle Aged; Mycobacterium Infections; Wound Infection | 1978 |
Antimicrobial therapy in the neonate.
Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Gentamicins; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Meningitis; Penicillins; Skin Diseases, Infectious; Tobramycin; Urinary Tract Infections | 1978 |
[Amikacin and tobramycin].
Topics: Amikacin; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Drug Resistance; Humans; Kanamycin; Tobramycin | 1978 |
Amikacin therapy of serious gram-negative bacillary infections in chronic hemodialysis patients.
Topics: Amikacin; Bacterial Infections; Female; Humans; Kanamycin; Male; Middle Aged; Renal Dialysis | 1978 |
Ototoxicity of tobramycin, gentamicin, amikacin and sisomicin in the guinea pig.
Topics: Acoustic Stimulation; Amikacin; Animals; Anti-Bacterial Agents; Cochlea; Evoked Potentials; Gentamicins; Guinea Pigs; Hearing Disorders; Kanamycin; Reflex; Sisomicin; Time Factors; Tobramycin | 1978 |
Newer antibiotics.
Topics: Amikacin; Humans; Kanamycin; Penicillins; Ticarcillin | 1978 |
Gentamicin-resistant gram-negative bacilli in hospital patients. Part II. In vitro aspects including susceptibility to tobramycin and amikacin.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Tobramycin | 1978 |
Neuromuscular blocking property of amikacin in man.
Topics: Adult; Amikacin; Calcium Chloride; Edrophonium; Female; Humans; Kanamycin; Male; Middle Aged; Neuromuscular Blocking Agents; Neuromuscular Junction | 1978 |
[Microbiology and pharmacokinetics of gentamicin, sisomicin, netilmicin and amikacin].
Topics: Amikacin; Bacteria; Gentamicins; Humans; Kanamycin; Kinetics; Sisomicin | 1978 |
Cerebrospinal fluid penetration of amikacin.
Topics: Adult; Amikacin; Humans; Kanamycin; Time Factors | 1978 |
A possible hazard of prolonged neuromuscular blockade by amikacin.
Topics: Adult; Amikacin; Anesthesia; Female; Humans; Kanamycin; Male; Neuromuscular Blocking Agents; Time Factors | 1978 |
Disposition studies with amikacin after rapid intravenous and intramuscular administration to human volunteers.
Topics: Adult; Amikacin; Female; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Kinetics; Male; Time Factors | 1978 |
A pharmacological study of UK-18,892 and amikacin.
Topics: Adult; Amikacin; Half-Life; Humans; Kanamycin; Male | 1978 |
[Clinical experience with amikacin for chronic complicated urinary tract infections in myelopathogenic bladder. Clinical effect against gentamicin-resistant bacteria (author's transl)].
Topics: Adult; Aged; Amikacin; Chronic Disease; Drug Evaluation; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Male; Middle Aged; Spinal Cord Injuries; Urinary Bladder, Neurogenic; Urinary Tract Infections | 1978 |
[Clinical experience with amikacin for respiratory infections due to gentamicin-resistant bacteria (author's transl)].
Topics: Aged; Amikacin; Drug Resistance, Microbial; Empyema; Female; Gentamicins; Humans; Kanamycin; Lung Abscess; Middle Aged; Respiratory Tract Infections | 1978 |
Measurement of three aminoglycosiee antibiotics with a single radioimmunoassay system.
Topics: Amikacin; Anti-Bacterial Agents; Gentamicins; Humans; Immune Sera; Kanamycin; Radioimmunoassay; Tobramycin | 1978 |
[New antibiotics in the treatment of urinary tract infections].
Topics: Amikacin; Amoxicillin; Ampicillin; Carbenicillin; Humans; Kanamycin; Pivampicillin; Sulfamethoxazole; Trimethoprim; Urinary Tract Infections | 1978 |
Prudent use of the aminoglycosides.
Topics: Amikacin; Aminoglycosides; Bacteria; Bacterial Infections; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Drug Therapy, Combination; Ear; Gentamicins; Humans; Kanamycin; Kidney; Tobramycin | 1978 |
Effects of hypoxemia upon aminoglycoside serum pharmacokinetics in animals.
Topics: Amikacin; Animals; Animals, Newborn; Gentamicins; Half-Life; Hypoxia; Kanamycin; Male; Rabbits; Rats | 1978 |
Comparative nephrotoxicity of aminoglycoside antibiotics in rats.
Topics: Amikacin; Aminoglycosides; Animals; Blood Urea Nitrogen; Dose-Response Relationship, Drug; Gentamicins; Kanamycin; Kidney; Male; Osmolar Concentration; Potassium; Proteinuria; Rats; Sisomicin; Sodium | 1978 |
The necessity of increased doses of amikacin in burn patients.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Burns; Creatinine; Half-Life; Humans; Infant; Kanamycin; Middle Aged | 1978 |
Amikacin serum concentrations: prediction of levels and dosage guidelines.
Topics: Adult; Amikacin; Body Weight; Computers; Creatinine; Humans; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Kidney Diseases; Mathematics | 1978 |
Antibiotic-associated colitis: report of a case.
Topics: Amikacin; Enterobacteriaceae Infections; Enterocolitis, Pseudomembranous; Humans; Injections, Intraperitoneal; Kanamycin; Male; Middle Aged; Peritonitis; Vancomycin | 1978 |
Activity of amikacin, erythromycin and doxycyline against Mycobacterium chelonei and Mycobacterium fortuitum.
Topics: Amikacin; Doxycycline; Erythromycin; Humans; Kanamycin; Mycobacterium; Mycobacterium Infections | 1978 |
In vitro activity of Sch 21420, derivative of gentamicin B, compared to that of amikacin.
Topics: Acetyltransferases; Amikacin; Aminoglycosides; Bacteria; Drug Resistance, Microbial; Gentamicins; Kanamycin; Microbial Sensitivity Tests | 1978 |
[Clinical and bacteriological evaluation of Amikin (Amikacin sulfate) by Bristol-Myers].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Drug Resistance, Microbial; Female; Gentamicins; Humans; Kanamycin; Male; Middle Aged | 1978 |
Renal accumulation of amikacin, tobramycin and gentamycin in the rat.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Female; Gentamicins; Kanamycin; Kidney; Kidney Diseases; Rats; Solubility; Tobramycin | 1978 |
The nephrotoxicity and renal accumulation of amikacin, tobramycin and gentamycin in rats, rabbits and guinea pigs.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Female; Gentamicins; Guinea Pigs; Kanamycin; Kidney; Organ Size; Rabbits; Rats; Tobramycin | 1978 |
Aminoglycoside clearance in patients with cystic fibrosis.
Topics: Amikacin; Child; Cystic Fibrosis; Humans; Kanamycin; Kidney | 1979 |
In vitro sensitivity of hospital strains of Serratia marcescens to chemotherapeutic agents.
Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Carbenicillin; Chloramphenicol; Cross Infection; Erythromycin; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Nalidixic Acid; Novobiocin; Rifampin; Serratia marcescens; Sputum; Streptomycin; Sulfamethoxazole; Tetracycline; Trimethoprim; Urine; Wound Infection | 1976 |
Antibacterial activity of ribostamycin on Enterobacteriaceae.
Topics: Amikacin; Anti-Bacterial Agents; Citrobacter; Enterobacteriaceae; Escherichia coli; Gentamicins; Kanamycin; Klebsiella pneumoniae; Microbial Sensitivity Tests; Proteus mirabilis; Ribostamycin | 1976 |
Isolation and characterization of mutants of Escherichia coli K12 resistant to the new aminoglycoside antibiotic, amikacin.
Topics: Amikacin; Chromosome Mapping; Drug Resistance, Microbial; Escherichia coli; Gentamicins; Kanamycin; Mutation; Neomycin; Transduction, Genetic | 1976 |
Intrathecal amikacin administration. Use in the treatment of gentamicin-resistant Klebsiella pneumoniae meningitis.
Topics: Adult; Amikacin; Craniocerebral Trauma; Drug Resistance, Microbial; Gentamicins; Humans; Injections, Spinal; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Male; Meningitis | 1976 |
[Antimicrobial effectiveness of sisomicin. I: In vitro activity of sisomicin compared with gentamicin, tobramycin, amikacin and kanamycin (author's transl)].
Topics: Amikacin; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; Gentamicins; Kanamycin; Klebsiella; Microbial Sensitivity Tests; Proteus; Pseudomonas; Serratia marcescens; Sisomicin; Staphylococcus aureus; Tobramycin | 1976 |
In vitro activity of gentamicin, amikacin and netilmicin alone and in combination with carbenicillin against Serratia marcescens.
Topics: Amikacin; Anti-Bacterial Agents; Carbenicillin; Drug Synergism; Gentamicins; Kanamycin; Serratia marcescens; Sisomicin | 1976 |
Efficacy of amikacin in septic abortion: serum and urine antibiotic concentrations.
Topics: Abortion, Septic; Adolescent; Adult; Amikacin; Curettage; Escherichia coli Infections; Female; Humans; Kanamycin; Pregnancy | 1976 |
Comparison of the in vitro activities of BB-K8 and three other aminoglycosides against 215 strains of Pseudomonas and Enterobacteriaceae with variable sensitivity to kanamycin and gentamicin.
Topics: Amikacin; Aminoglycosides; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; Gentamicins; Kanamycin; Klebsiella; Klebsiella pneumoniae; Microbial Sensitivity Tests; Proteus mirabilis; Providencia; Pseudomonas; Pseudomonas aeruginosa; Serratia marcescens | 1975 |
[Amikacin treatment of septicemia due to gentamicin-resistant gram-negative bacilli (author's transl)].
Topics: Aged; Amikacin; Aorta, Thoracic; Aortic Aneurysm; Cephaloridine; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Parkinson Disease; Proteus Infections; Proteus mirabilis; Pseudomonas aeruginosa; Pseudomonas Infections; Subarachnoid Hemorrhage | 1975 |
[Treatment of dermatological cases with BB-K8 (author's transl)].
Topics: Adolescent; Adult; Aged; Amikacin; Child, Preschool; Drug Evaluation; Erythema Induratum; Female; Furunculosis; Humans; Infant; Kanamycin; Male; Panniculitis, Nodular Nonsuppurative; Pressure Ulcer; Pseudomonas aeruginosa; Skin Diseases, Infectious; Staphylococcus | 1975 |
[Experimental studies on the anti-tuberculous effect of BB-K8 (author's transl)].
Topics: Amikacin; Animals; Kanamycin; Male; Mice; Mycobacterium tuberculosis; Tuberculosis | 1975 |
Bactericidal efficacy of Sch 20569 and amikacin against gentamicin-sensitive and -resistant organisms.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Citrobacter; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; Gentamicins; Kanamycin; Klebsiella; Proteus; Pseudomonas aeruginosa; Serratia; Sisomicin; Staphylococcus aureus | 1976 |
Effect of clindamycin on the in vitro activity of amikacin and gentamicin against gram-negative bacilli.
Topics: Amikacin; Clindamycin; Culture Media; Drug Interactions; Escherichia coli; Gentamicins; Kanamycin; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Time Factors | 1976 |
Activity of amikacin at sub-inhibitory levels.
Topics: Amikacin; Kanamycin; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Time Factors | 1976 |
Comparative evaluation of five aminoglycosides for treatment.
Topics: Amikacin; Aminoglycosides; Enterobacter; Escherichia coli; Gentamicins; Humans; Kanamycin; Kinetics; Klebsiella; Microbial Sensitivity Tests; Providencia; Pseudomonas aeruginosa; Serratia marcescens; Sisomicin; Tobramycin | 1976 |
Comparative activity of netilmicin, gentamicin, amikacin, and tobramycin against Pseudomonas aeruginosa and Enterobacteriaceae.
Topics: Amikacin; Anti-Bacterial Agents; Carbenicillin; Enterobacteriaceae; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Sisomicin; Tobramycin | 1976 |
Discovery, chemistry, and activity of amikacin.
Topics: Amikacin; Chemical Phenomena; Chemistry; Enterobacteriaceae; Kanamycin; Mycobacterium tuberculosis; Staphylococcus; Streptococcus | 1976 |
In vitro susceptibility of clinically important bacteria to amikacin: correlation of results of broth dilution and disk sensitivity tests and effect of medium composition.
Topics: Amikacin; Carbenicillin; Culture Media; Enterobacteriaceae; Escherichia coli; Gentamicins; Kanamycin; Klebsiella; Microbial Sensitivity Tests; Providencia; Pseudomonas aeruginosa; Serratia; Sisomicin; Staphylococcus aureus; Tobramycin | 1976 |
In vitro susceptibility of recently isolated gram-negative bacteria to gentamicin, sisomicin, tobramycin, and amikacin.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Enterobacteriaceae; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Sisomicin; Staphylococcus aureus; Tobramycin | 1976 |
A Rapid, simple method for demonstrating synergy of amikacin and penicillin against various microorganisms.
Topics: Amikacin; Ampicillin; Carbenicillin; Drug Synergism; Enterococcus faecalis; Kanamycin; Microbial Sensitivity Tests; Penicillin G; Penicillins; Proteus mirabilis | 1976 |
Suceptibility of aminoglycoside-resistant gram-negative bacilli to amikacin: delineation of individual resistance patterns.
Topics: Amikacin; Aminoglycosides; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Kanamycin; Moraxella; Neomycin; Paromomycin; Pseudomonas aeruginosa; Tobramycin | 1976 |
Susceptibility of recently isolated bacteria to amikacin in vitro: comparisons with four other aminoglycoside antibiotics.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Haemophilus influenzae; Kanamycin; Neisseria gonorrhoeae; Neomycin; Pseudomonas aeruginosa; Staphylococcus; Streptococcus; Streptomycin | 1976 |
Pharmacokinetic and clinical studies with amikacin, a new aminoglycoside antibiotic.
Topics: Adult; Aged; Amikacin; Bacterial Infections; Bronchitis; Chronic Disease; Enterobacteriaceae Infections; Female; Humans; Kanamycin; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Urinary Tract Infections | 1976 |
Clinical evaluation of amikacin in treatment of infections due to gram-negative aerobic bacilli.
Topics: Adolescent; Adult; Aged; Amikacin; Aminoglycosides; Bacterial Infections; Enterobacteriaceae Infections; Humans; Kanamycin; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Urinary Tract Infections | 1976 |
Susceptibility of current clinical isolates of Pseudomonas aeruginosa and enteric gram-negative bacilli to amikacin and other aminoglycoside antibiotics.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Enterobacteriaceae; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Paromomycin; Pseudomonas aeruginosa; Streptomycin; Tobramycin | 1976 |
Use of Amikacin in a hospital for children: microbiological and clinical studies.
Topics: Amikacin; Aminoglycosides; Bacterial Infections; Child; Child, Preschool; Cross Infection; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Kanamycin; Kidney Failure, Chronic; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Urinary Tract Infections | 1976 |
Activity of amikacin, gentamicin and kanamycin against Pseudomonas aeruginosa.
Topics: Adult; Amikacin; Gentamicins; Humans; Injections, Intramuscular; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Time Factors | 1976 |
Effect of combined use of antibiotics against Pseudomonas aeruginosa in vitro.
Topics: Amikacin; Colistin; Drug Combinations; Drug Resistance, Microbial; Gentamicins; Kanamycin; Pseudomonas aeruginosa | 1976 |
Pharmacokinetics of amikacin during hemodialysis and peritoneal dialysis.
Topics: Adult; Amikacin; Female; Half-Life; Humans; Kanamycin; Kinetics; Male; Middle Aged; Peritoneal Dialysis; Renal Dialysis | 1977 |
Testing for ototoxicity: amikacin and gentamicin.
Topics: Amikacin; Cochlea; Gentamicins; Humans; Kanamycin; Vestibular Nerve | 1977 |
Plasmid-medicated aminoglycoside phosphotransferase of broad substrate range that phosphorylates amikacin.
Topics: Amikacin; Aminoglycosides; Extrachromosomal Inheritance; Kanamycin; Phosphotransferases; Plasmids; Staphylococcus | 1977 |
[Ototoxic effect of BB-K8 administered to pregnant guinea pigs on development of inner ear of intrauterine litters (author's transl)].
Topics: Amikacin; Animals; Animals, Newborn; Body Weight; Ear, Inner; Female; Fetus; Guinea Pigs; Kanamycin; Maternal-Fetal Exchange; Pregnancy; Reflex | 1977 |
Maternal-fetal pharmacological activity of amikacin.
Topics: Amikacin; Amniotic Fluid; Embryo, Mammalian; Female; Fetal Blood; Fetus; Gestational Age; Humans; Kanamycin; Kidney; Lung; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second | 1977 |
Symposium perspective.
Topics: Amikacin; Bacterial Infections; Drug Resistance, Microbial; Humans; Kanamycin | 1977 |
Resistance to gentamicin, tobramycin and amikacin among clinical isolates of bacteria.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Streptomycin; Tobramycin | 1977 |
Gentamicin/amikacin-resistant gram-negative bacilli at Detroit General Hospital, 1975-1976.
Topics: Amikacin; Bacteria; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin | 1977 |
Treatment of hospita-acquired infections with amikacin.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Cross Infection; Female; Humans; Kanamycin; Male; Middle Aged; Proteus; Proteus Infections; Urinary Tract Infections | 1977 |
Ototoxicity and nephrotoxicity of amikacin: an overview of phase II and phase III experience in the United States.
Topics: Adult; Aged; Amikacin; Audiometry; Child; Creatinine; Ear; Hearing Disorders; Humans; Kanamycin; Kidney; Kidney Diseases; Middle Aged; United States; Vestibulocochlear Nerve | 1977 |
Amikacin therapy for gram-negative septicemia.
Topics: Adult; Aged; Amikacin; Creatinine; Drug Resistance, Microbial; Female; Hearing Disorders; Humans; Kanamycin; Kidney Diseases; Male; Middle Aged; Sepsis | 1977 |
Amikacin therapy of gram-negative bacteremia.
Topics: Amikacin; Gentamicins; Hearing Disorders; Humans; Kanamycin; Sepsis | 1977 |
Review of 152 patients with bacteremias treated with amikacin.
Topics: Adult; Aged; Amikacin; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Middle Aged; Sepsis | 1977 |
Amikacin treatment of pulmonary infections involving gentamicin-resistant gram-negative bacilli.
Topics: Amikacin; Bacteria; Bacterial Infections; Cross Infection; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Lung Diseases | 1977 |
Amikacin in the treatment of gram-negative pneumonia.
Topics: Adult; Aged; Amikacin; Gentamicins; Humans; Kanamycin; Middle Aged; Pneumonia | 1977 |
An overview of pediatric experience with amikacin.
Topics: Amikacin; Bacterial Infections; Child; Cross Infection; Enterobacteriaceae Infections; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin | 1977 |
The pharmacokinetics of amikacin in children.
Topics: Adolescent; Amikacin; Anemia, Aplastic; Appendicitis; Child; Child, Preschool; Cystic Fibrosis; Female; Half-Life; Humans; Kanamycin; Kidney; Leukemia; Male; Metabolic Clearance Rate; Neoplasms; Neutropenia; Pelvic Inflammatory Disease | 1977 |
Commentary: assessment of amikacin for pediatric usage.
Topics: Adult; Age Factors; Amikacin; Child; Humans; Infant; Infant, Newborn; Kanamycin; Microbial Sensitivity Tests | 1977 |
In vitro activity of netilmicin compared with gentamicin, tobramycin, amikacin, and kanamycin.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Sisomicin; Tobramycin | 1977 |
Effects of gestational age, birth weight, and hypoxemia on pharmacokinetics of amikacin in serum of infants.
Topics: Amikacin; Bacterial Infections; Birth Weight; Female; Gestational Age; Humans; Hypoxia; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Male | 1977 |
Distribution of amikacin in serum, muscle, and fat in children after a single intramuscular injection.
Topics: Adipose Tissue; Amikacin; Child; Female; Humans; Injections, Intramuscular; Kanamycin; Male; Muscles; Time Factors | 1977 |
Distribution of gentamicin and amikacin in rabbit tissues.
Topics: Amikacin; Animals; Female; Gentamicins; Kanamycin; Kidney; Male; Rabbits | 1977 |
Clinical pharmacology of amikacin sulphate: blood, urinary and tissue concentrations in the terminal stage of pregnancy.
Topics: Amikacin; Female; Humans; Kanamycin; Pregnancy; Pregnancy Trimester, Third | 1977 |
Gram-negative sepsis: part II. Management.
Topics: Acidosis; Adult; Amikacin; Child; Chloramphenicol; Clindamycin; Disseminated Intravascular Coagulation; Dopamine; Gentamicins; Heart Failure; Humans; Isoproterenol; Kanamycin; Kidney Diseases; Metaraminol; Phenoxybenzamine; Respiratory Insufficiency; Sepsis; Tobramycin | 1977 |
Amikacin--the latest aminoglycoside.
Topics: Amikacin; Humans; Kanamycin; Kinetics | 1977 |
Comparative ototoxicity of BB-K8 (amikacin), gentamicin, sisomicin and tobramycin in the guinea pig.
Topics: Acoustic Stimulation; Amikacin; Animals; Anti-Bacterial Agents; Cochlea; Electrophysiology; Gentamicins; Guinea Pigs; Hearing Disorders; Kanamycin; Reflex; Sisomicin; Tobramycin | 1977 |
Comparative ototoxicity of amikacin and gentamicin in cats.
Topics: Acoustic Stimulation; Action Potentials; Amikacin; Animals; Behavior, Animal; Cats; Ear Diseases; Female; Gentamicins; Hearing Disorders; Kanamycin; Labyrinth Diseases; Male; Time Factors | 1977 |
[New aminoglycoside antibiotics].
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Enterobacteriaceae Infections; Humans; Kanamycin; Pseudomonas Infections; Tobramycin | 1977 |
[Therapeutic experience of Proteus morganii septicemia with amikacin (author's transl)].
Topics: Amikacin; Humans; Intracranial Aneurysm; Kanamycin; Male; Middle Aged; Proteus Infections; Sepsis | 1977 |
Serum levels and urinary concentrations of kanamicin, bekanamicin and amikacin (BB-K8) in diabetic children and a control group.
Topics: Adolescent; Amikacin; Child; Diabetes Mellitus, Type 1; Humans; Kanamycin | 1977 |
Concentrations of gentamicin and amikacin in human kidneys.
Topics: Aged; Amikacin; Creatine; Gentamicins; Humans; In Vitro Techniques; Infant, Newborn; Kanamycin; Kidney; Kidney Cortex; Kidney Medulla; Middle Aged | 1976 |
Ototoxicity of amikacin.
Topics: Amikacin; Cochlea; Hearing Disorders; Hearing Tests; Humans; Kanamycin; Risk | 1976 |
[Clinical results with amikacin (BB-K8) in respiratory infections (author's transl)].
Topics: Aged; Amikacin; Female; Humans; Kanamycin; Male; Middle Aged; Respiratory Tract Infections | 1976 |
[Amikacin].
Topics: Amikacin; Kanamycin | 1976 |
Pharmacokinetics and ototoxicity of gentamicin, tobramycin, and amikacin.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Ear; Endolymph; Female; Gentamicins; Guinea Pigs; Kanamycin; Kinetics; Male; Perilymph; Tobramycin | 1976 |
[New drugs: Amikacin].
Topics: Adult; Amikacin; Child; Drug Therapy, Combination; Humans; Infant, Newborn; Kanamycin; Respiratory Tract Infections; Skin Diseases, Infectious; Urinary Tract Infections | 1976 |
Amikacin.
Topics: Amikacin; Bacteria; Drug Resistance, Microbial; Humans; Infant, Newborn; Kanamycin; Sepsis | 1976 |
[The antibacterial activity of amikacin in comparison with four other aminoglycoside antibiotics (proceedings)].
Topics: Amikacin; Aminoglycosides; Bacteria; Kanamycin; Microbial Sensitivity Tests | 1976 |
Amikacin in newborn infants: comparative pharmacology with kanamycin and clinical efficacy in 45 neonates with bacterial diseases.
Topics: Amikacin; Bacterial Infections; Humans; Infant, Newborn; Kanamycin | 1976 |
Effect of renal failure and dialysis on the serum concentration of the aminoglycoside amikacin.
Topics: Adult; Amikacin; Female; Half-Life; Humans; Infusions, Parenteral; Kanamycin; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Renal Dialysis | 1976 |
Selection and characterization of strains of Staphylococcus aureus displaying unusual resistance to aminoglycosides.
Topics: Amikacin; Aminoglycosides; Drug Resistance, Microbial; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Sisomicin; Staphylococcus aureus; Time Factors; Tobramycin | 1976 |
Amikacin in treatment of infections caused by gram-negative bacteria resistant to gentamicin and other aminoglycosides: clinical and bacteriologic results.
Topics: Adolescent; Adult; Aged; Amikacin; Aminoglycosides; Bacterial Infections; Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Kanamycin; Male; Micrococcus; Middle Aged; Respiratory Tract Infections; Urinary Tract Infections | 1976 |
Clinical pharmacology of amikacin and kanamycin.
Topics: Adult; Amikacin; Blood Proteins; Humans; Kanamycin; Male; Protein Binding | 1976 |
Pharmacokinetics of amikacin in patients with normal or impaired renal function: radioenzymatic acetylation assay.
Topics: Acetylation; Adolescent; Adult; Aged; Amikacin; Coenzyme A; Creatinine; Female; Humans; Kanamycin; Kidney Failure, Chronic; Male; Middle Aged | 1976 |
Pharmacokinetics of amikacin in patients with renal insufficiency: relation of half-life and creatinine clearance.
Topics: Aged; Amikacin; Creatinine; Female; Half-Life; Humans; Kanamycin; Kidney Failure, Chronic; Male; Middle Aged | 1976 |
Pharmacokinetics of amikacin in patients with impaired renal function.
Topics: Adolescent; Adult; Aged; Amikacin; Creatinine; Female; Half-Life; Humans; Kanamycin; Kidney Failure, Chronic; Male; Middle Aged | 1976 |
Pharmacokinetics of amikacin for treatment of urinary tract infections in patients with reduced renal function.
Topics: Aged; Amikacin; Chronic Disease; Drug Evaluation; Glomerular Filtration Rate; Half-Life; Humans; Kanamycin; Kidney Diseases; Male; Middle Aged; Urinary Tract Infections | 1976 |
Amikacin in obstetric, gynecologic, and neonatal infections: laboratory and clinical studies.
Topics: Amikacin; Bacterial Infections; Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Fetal Blood; Gentamicins; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Kidney Failure, Chronic; Pregnancy; Pregnancy Complications, Infectious; Pseudomonas Infections; Urinary Tract Infections | 1976 |
Amikacin for treatment of septic abortions: summary.
Topics: Abortion, Septic; Amikacin; Enterobacteriaceae Infections; Female; Humans; Kanamycin; Pregnancy; Sepsis | 1976 |
Preliminary clinical trial with amikacin in chronic recurrent gram-negative bacterial infections refractory to other antimicrobial agents.
Topics: Adult; Aged; Amikacin; Bacterial Infections; Chronic Disease; Enterobacteriaceae Infections; Female; Humans; Kanamycin; Male; Middle Aged; Peritonitis; Pseudomonas Infections; Recurrence; Respiratory Tract Infections; Sepsis; Urinary Tract Infections | 1976 |
Clinical and laboratory studies with amikacin in newborns, infants, and children.
Topics: Adolescent; Amikacin; Bacterial Infections; Child; Child, Preschool; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Male; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas Infections | 1976 |
Amikacin for treatment of infections in patients with malignant diseases.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Blood Cell Count; Enterobacteriaceae Infections; Female; Humans; Kanamycin; Male; Middle Aged; Neoplasms; Neutrophils; Pseudomonas Infections | 1976 |
Amikacin therapy for severe gram-negative sepsis: efficacy in infections involving gentamicin-resistant organisms.
Topics: Amikacin; Bacterial Infections; Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Kanamycin; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas Infections; Sepsis | 1976 |
Amikacin pharmacokinetics in the therapy of childhood urinary tract infection.
Topics: Amikacin; Child; Child, Preschool; Female; Humans; Kanamycin; Recurrence; Urinary Tract Infections | 1976 |
Bacterial prostatitis treated by local antibiotics.
Topics: Amikacin; Bacterial Infections; Cefazolin; Cephalosporins; Follow-Up Studies; Gentamicins; Humans; Injections; Kanamycin; Male; Prostatitis | 1976 |
Amikacin.
Topics: Amikacin; Bacterial Infections; Drug Resistance, Microbial; Gentamicins; Gram-Negative Aerobic Bacteria; Humans; Kanamycin; Leukopenia; Tobramycin | 1976 |
Tobramycin, amikacin, sissomicin, and gentamicin resistant Gram-negative rods.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Gentamicins; Kanamycin; Sisomicin; Tobramycin | 1976 |
Hemodialyzer clearances of gentamicin, kanamycin, tobramycin, amikacin, ethambutol, procainamide, and flucytosine, with a technique for planning therapy.
Topics: Amikacin; Creatinine; Drug Therapy; Ethambutol; Flucytosine; Gentamicins; Humans; Kanamycin; Models, Biological; Pentetic Acid; Pharmaceutical Preparations; Procainamide; Renal Dialysis; Tobramycin | 1976 |
[Study of the microbiological activity in vitro of BB-K-8, a new aminoglycoside antibiotic].
Topics: Amikacin; Bacteria; Kanamycin; Microbial Sensitivity Tests | 1976 |
Amikacin (BBK8) in infections due to gram-negative organisms in children over the age of one month.
Topics: Adolescent; Amikacin; Child; Child, Preschool; Drug Administration Schedule; Drug Evaluation; Enterobacteriaceae Infections; Female; Humans; Infant; Injections, Intramuscular; Kanamycin; Male; Microbial Sensitivity Tests; Pseudomonas Infections | 1976 |
[Pharmacokinetics and clinical experiences with a new aminoglycoside antibioticum: amikacin].
Topics: Adult; Amikacin; Bacterial Infections; Cross Infection; Drug Evaluation; Female; Humans; Kanamycin; Male; Middle Aged | 1976 |
125I-Radioimmunoassay of amikacin and comparison with a microbioassay.
Topics: Amikacin; Animals; Antibody Specificity; Biological Assay; Immunization; Iodine Radioisotopes; Kanamycin; Methods; Rabbits; Radioimmunoassay | 1976 |
Effects of ampicillin-amikacin and ampicillin-rifampin on enterococci.
Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Drug Antagonism; Kanamycin; Penicillin Resistance; Rifampin; Streptococcus | 1976 |
[Drug sensitivity of Yersinia enterocolitica and Yersinia pseudotuberculosis].
Topics: Amikacin; Animals; Antibiotics, Antitubercular; Cephalosporins; Chloramphenicol; Dogs; Gentamicins; Humans; Kanamycin; Mice; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Tetracyclines; Tobramycin; Yersinia | 1976 |
Multidrug-resistant Proteus rettgeri: an emerging problem.
Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Cephalothin; Cross Infection; Gentamicins; Humans; Kanamycin; Penicillin Resistance; Proteus; Proteus Infections; R Factors; Urinary Tract Infections | 1976 |
Comparative pharmacokinetics of lividomycin, amikacin and sisomicin in normal subjects and in uraemic patients.
Topics: Adult; Amikacin; Biological Assay; Gentamicins; Half-Life; Humans; Kanamycin; Kinetics; Middle Aged; Paromomycin; Sisomicin; Uremia | 1976 |
Penetration of amikacin into the aphakic eye.
Topics: Absorption; Amikacin; Animals; Aqueous Humor; Cataract Extraction; Endophthalmitis; Kanamycin; Lens, Crystalline; Ophthalmic Solutions; Postoperative Complications; Pseudomonas Infections; Rats; Vitreous Body | 1975 |
Amikacin in the treatment of gram-negative bronchopulmonary infections.
Topics: Acute Disease; Adult; Aged; Amikacin; Enterobacteriaceae Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Kanamycin; Middle Aged; Pseudomonas Infections; Respiratory Tract Infections | 1976 |
[A case of E. coli septicemia successfully treated with amikacin (author's transl)].
Topics: Amikacin; Carbenicillin; Cefazolin; Drug Therapy, Combination; Escherichia coli Infections; Gentamicins; Humans; Kanamycin; Male; Middle Aged; Sepsis | 1975 |
Effectiveness of carbenicillin - aminoglycoside and of cephalothin-aminoglycoside combinations against enterococci in vitro.
Topics: Amikacin; Aminoglycosides; Carbenicillin; Cephalothin; Drug Antagonism; Drug Synergism; Gentamicins; Humans; Intestines; Kanamycin; Microbial Sensitivity Tests; Sisomicin; Streptococcus; Tobramycin | 1975 |
In vitro antibacterial activity of amikacin, a new aminoglycoside, against clinical bacterial isolates from children.
Topics: Amikacin; Bacteria; Child; Humans; Infections; Kanamycin; Microbial Sensitivity Tests | 1975 |
Improved acetylating radioenzymatic assay of amikacin, tobramycin, and sisomicin in serum.
Topics: Amikacin; Anti-Bacterial Agents; Coenzyme A; Kanamycin; Methods; Sisomicin; Tobramycin | 1975 |
Scientific commentary. Drug absorption and disposition as monitors of safety and efficacy.
Topics: Absorption; Amikacin; Animals; Biological Availability; Dogs; Drug Evaluation, Preclinical; Humans; Hypnotics and Sedatives; Kanamycin; Kinetics; Monitoring, Physiologic; Pharmaceutical Preparations; Solubility; United States; United States Food and Drug Administration | 1975 |
[Comparison of absorption and excretion of powdery preparation for injection and liquid preparation of BB-K8 (amikacin) (author's transl)].
Topics: Adult; Aged; Amikacin; Bronchitis; Cystitis; Drug Evaluation; Female; Humans; Injections, Intramuscular; Kanamycin; Male; Middle Aged; Pneumonia; Powders; Solutions | 1975 |
[Evaluation of ototoxicity of amikacin (BB-K8) by animal test (author's transl)].
Topics: Amikacin; Animals; Auditory Threshold; Body Weight; Gentamicins; Guinea Pigs; Hearing; Hearing Disorders; Injections, Intramuscular; Kanamycin; Organ of Corti | 1975 |
[Teratological studies of amikacin (BB-K8) in rabbit (author's transl)].
Topics: Abnormalities, Drug-Induced; Amikacin; Animals; Body Weight; Embryo Implantation; Female; Fetus; Injections, Intramuscular; Kanamycin; Osteogenesis; Pregnancy; Rabbits | 1975 |
[Teratological studies of amikacin (BB-K8) in mice and rats (author's transl)].
Topics: Abnormalities, Drug-Induced; Amikacin; Animals; Animals, Newborn; Body Weight; Drinking; Feeding Behavior; Female; Fetus; Growth; Injections, Intradermal; Kanamycin; Kidney Diseases; Mice; Osteogenesis; Pregnancy; Rats | 1975 |
[Pharmacological studies of amikacin (BB-K8) (author's transl)].
Topics: Amikacin; Analgesics; Anesthetics, Local; Animals; Blood Coagulation; Blood Pressure; Capillary Permeability; Cats; Central Nervous System; Gastrointestinal Motility; Heart; Heart Rate; In Vitro Techniques; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Kanamycin; Male; Mice; Muscle, Smooth; Neuromuscular Junction; Rabbits; Rats; Respiration | 1975 |
Comparative effects of kanamycin and amikacin on aortic blood pressure, cardiac rate and surface electrocardiogram in the conscious dog.
Topics: Amikacin; Animals; Behavior, Animal; Blood Pressure; Dogs; Electrocardiography; Heart Rate; Kanamycin | 1975 |
[Studies on the toxicity of amikacin (BB-K8), I. Acute toxicity and subacute toxicity in rats (author's transl)].
Topics: Administration, Oral; Amikacin; Animals; Blood Urea Nitrogen; Body Weight; Dilatation, Pathologic; Drinking; Feeding Behavior; Female; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Kanamycin; Kidney; Kidney Tubules; Lethal Dose 50; Male; Mice; Organ Size; Rabbits; Rats | 1975 |
[Studies on the toxicity of amikacin (BB-K8).II. Chronic toxicity in rats (author's transl)].
Topics: Amikacin; Animals; Blood Urea Nitrogen; Body Weight; Dilatation, Pathologic; Drinking; Drug Evaluation, Preclinical; Feeding Behavior; Female; Injections, Subcutaneous; Kanamycin; Kidney; Kidney Tubules; Male; Organ Size; Rats; Sex Factors | 1975 |
[Studies on the toxicity of amikacin (BB-K8),III. Subacute toxicity of amikacin (BB-K8) in dogs (author's transl)].
Topics: Acute Disease; Amikacin; Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Dilatation, Pathologic; Dogs; Drinking; Drug Evaluation, Preclinical; Feeding Behavior; Female; Injections, Intramuscular; Kanamycin; Kidney Diseases; Kidney Tubules; Male; Sex Factors | 1975 |
[Studies on the toxicity of amikacin (BB-K8). Chronic toxicity in dogs (author's transl)].
Topics: Amikacin; Animals; Anorexia; Blood Urea Nitrogen; Body Weight; Creatinine; Dogs; Drinking; Drug Evaluation, Preclinical; Feeding Behavior; Female; Injections, Intramuscular; Kanamycin; Leukocyte Count; Male; Sex Factors | 1975 |
Pharmacological evaluation of amikacin in neonates.
Topics: Amikacin; Enterobacteriaceae; Half-Life; Humans; Infant, Newborn; Infusions, Parenteral; Injections, Intramuscular; Kanamycin; Pseudomonas; Staphylococcus aureus | 1975 |
Nephrotoxicity of amikacin (BB-K8), an aminoglycoside antibiotic.
Topics: Amikacin; Animals; Dogs; Kanamycin; Kidney; Kidney Diseases; Rats; Saimiri | 1975 |
Amikacin: a rapid and sensitive radioimmunoassay.
Topics: Amikacin; Animals; Kanamycin; Rabbits; Radioimmunoassay | 1975 |
Amikacin therapy for serious gram-negative bacillary infections.
Topics: Adult; Aged; Amikacin; Bacterial Infections; Ear, Inner; Female; Humans; Kanamycin; Kidney; Male; Middle Aged; Osteomyelitis; Peritonitis; Pneumonia; Sepsis; Urinary Tract Infections | 1975 |
Emergence of resistance to amikacin during treatment of burn wounds: the role of antimicrobial susceptibility testing.
Topics: Adolescent; Adult; Aged; Amikacin; Burns; Child; Child, Preschool; Drug Resistance, Microbial; Humans; Kanamycin; Microbial Sensitivity Tests; Middle Aged; Providencia; R Factors; Wound Infection | 1976 |
In vitro activity, synergism, and testing parameters of amikacin, with comparisons to other aminoglycoside antibiotics.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Carbenicillin; Drug Synergism; Gentamicins; Kanamycin; Species Specificity; Tobramycin | 1976 |
Kinetics and dose calculations of amikacin in the newborn.
Topics: Absorption; Aging; Amikacin; Drug Administration Schedule; Humans; Infant; Infant, Newborn; Infusions, Parenteral; Injections, Intramuscular; Kanamycin; Kinetics; Models, Biological | 1976 |
[Cloning and expression of alpha-hydroxy-gamma-aminobutyl acylase gene of Bacillus circulans NRRL-B3312].
Topics: Acyltransferases; Amikacin; Bacillus; Cloning, Molecular; Gene Expression; Genes, Bacterial; Kanamycin; Plasmids | 1992 |
[Study of possible biological transformation of kanamycin to amikacin].
Topics: Acylation; Amikacin; Anti-Bacterial Agents; Bacillus; Butirosin Sulfate; Culture Media; Hexosamines; In Vitro Techniques; Kanamycin; Mutation | 1992 |
Maintenance requirements of Escherichia coli ATCC 25922 in the presence of sub-inhibitory concentrations of various antibiotics.
Topics: Amikacin; Anti-Bacterial Agents; Cell Division; Culture Media; Escherichia coli; Kanamycin; Kinetics; Microbial Sensitivity Tests; Models, Biological | 1992 |
High-level amikacin resistance in Escherichia coli due to phosphorylation and impaired aminoglycoside uptake.
Topics: Amikacin; Aminoglycosides; Dihydrostreptomycin Sulfate; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Kanamycin Kinase; Kinetics; Membrane Potentials; Mutation; Phosphorylation; Phosphotransferases; R Factors | 1986 |
MIC as a quantitative measurement of the susceptibility of Mycobacterium avium strains to seven antituberculosis drugs.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Culture Media; Ethionamide; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Rifampin; Streptomycin | 1988 |
Comparison of bactericidal activities of streptomycin, amikacin, kanamycin, and capreomycin against Mycobacterium avium and M. tuberculosis.
Topics: Acquired Immunodeficiency Syndrome; Amikacin; Anti-Bacterial Agents; Capreomycin; Kanamycin; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium Infections; Mycobacterium tuberculosis; Streptomycin | 1989 |
Recurrence of neuromuscular blockade after reversal of vecuronium in a patient receiving polymyxin/amikacin sternal irrigation.
Topics: Aged; Amikacin; Drug Synergism; Humans; Kanamycin; Male; Neuromuscular Blocking Agents; Neuromuscular Junction; Pancuronium; Polymyxins; Sternum; Therapeutic Irrigation; Vecuronium Bromide | 1986 |
Bactericidal activity of ciprofloxacin against amikacin- and cefotaxime-resistant gram-negative bacilli and methicillin-resistant staphylococci.
Topics: Amikacin; Cefotaxime; Ciprofloxacin; Cross Infection; Gram-Negative Bacteria; Humans; Kanamycin; Methicillin; Penicillin Resistance; Quinolines; Staphylococcus | 1986 |
In vivo efficacy of azlocillin and amikacin versus ciprofloxacin with and without amikacin in experimental right-sided endocarditis due to Pseudomonas aeruginosa.
Topics: Amikacin; Animals; Azlocillin; Ciprofloxacin; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Kanamycin; Penicillin Resistance; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Rabbits; Time Factors | 1986 |
Effects of aminoglycosides and spectinomycin on the synthesis and release of lipopolysaccharide by Escherichia coli.
Topics: Amikacin; Anti-Bacterial Agents; Chloramphenicol; Escherichia coli; Gentamicins; Kanamycin; Lipopolysaccharides; Spectinomycin; Tobramycin | 1988 |
Studies on antiviral agents. III. Synthesis and in vitro antiviral activity of 1-N-higher-acyl-3"-N-functionalized acylkanamycin A derivatives.
Topics: Amikacin; Antiviral Agents; Kanamycin; Orthomyxoviridae; Simplexvirus; Structure-Activity Relationship | 1985 |
Inhibition of SV40 DNA replication in vitro by 1-N-acyl-3"-N-(trifluoroacetyl) kanamycin.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Antiviral Agents; Aphidicolin; Deoxycytidine Monophosphate; Dibekacin; Diterpenes; DNA Replication; DNA, Viral; Haplorhini; Hygromycin B; Kanamycin; Nalidixic Acid; Novobiocin; Simian virus 40; Spectrophotometry; Streptomycin | 1986 |
Susceptibility of aerobic gram-negative bacilli to aminoglycosides. Effects of 45 months of amikacin as first-line aminoglycoside therapy.
Topics: Acetyltransferases; Amikacin; Aminoglycosides; Bacterial Infections; Drug Resistance, Microbial; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Kanamycin Kinase; Netilmicin; Nucleotidyltransferases; Phosphotransferases; Population Surveillance; Prospective Studies; Tobramycin | 1986 |
Transfer of amikacin resistance by closely related plasmids in members of the family Enterobacteriaceae isolated in Chile.
Topics: Amikacin; Aminoglycosides; Chile; DNA Restriction Enzymes; DNA, Bacterial; Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Kanamycin; Plasmids | 1986 |
Molecular cloning of amikacin resistance determinants from a Klebsiella pneumoniae plasmid.
Topics: Acetyltransferases; Amikacin; Cloning, Molecular; Conjugation, Genetic; DNA Restriction Enzymes; DNA, Bacterial; Genes, Bacterial; Gentamicins; Kanamycin; Kanamycin Kinase; Klebsiella pneumoniae; Phosphotransferases; R Factors; Tobramycin | 1986 |
[A mathematical study of the mortality curve of Escherichia coli exposed to aminoglycosides].
Topics: Amikacin; Anti-Bacterial Agents; Dibekacin; Dose-Response Relationship, Drug; Escherichia coli; Kanamycin; Netilmicin; Regression Analysis; Software | 1988 |
[Habekacin: a new aminoglycoside. Study of nephrotoxicity in rats in comparison with gentamicin, netilmicin and amikacin].
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Dibekacin; Female; Gentamicins; Kanamycin; Kidney Cortex; Kidney Diseases; Netilmicin; Rats; Rats, Inbred Strains | 1988 |
Serum bactericidal activity of mezlocillin, ceftazidime, mezlocillin/ceftazidime and mezlocillin/amikacin against Klebsiella pneumoniae and Pseudomonas aeruginosa.
Topics: Amikacin; Ceftazidime; Drug Evaluation; Drug Synergism; Humans; Kanamycin; Klebsiella pneumoniae; Mezlocillin; Pseudomonas aeruginosa | 1986 |
Effect of increasing doses of amikacin with or without piperacillin in the serum bactericidal test.
Topics: Adult; Amikacin; Drug Evaluation; Drug Synergism; Escherichia coli; Female; Humans; Kanamycin; Klebsiella pneumoniae; Male; Penicillin Resistance; Piperacillin; Pseudomonas aeruginosa | 1986 |
Emergence of resistance after therapy with antibiotics used alone or combined in a murine model.
Topics: Amikacin; Animals; Bacteria; Bacterial Infections; Ceftriaxone; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacter; Escherichia coli; Female; Kanamycin; Klebsiella pneumoniae; Mice; Norfloxacin; Pefloxacin; Peritonitis; Pseudomonas aeruginosa; Serratia marcescens; Staphylococcus aureus | 1986 |
Bactericidal activity and killing rate of serum from volunteers receiving pefloxacin alone or in combination with amikacin.
Topics: Amikacin; Ampicillin; Cephalothin; Drug Combinations; Drug Interactions; Enterobacteriaceae; Escherichia coli; Female; Humans; Infusions, Parenteral; Kanamycin; Klebsiella pneumoniae; Male; Norfloxacin; Oxacillin; Pefloxacin; Pseudomonas aeruginosa; Staphylococcus aureus; Ticarcillin | 1986 |
Synergistic activity of amikacin with aztreonam against Pseudomonas aeruginosa and other gram-negative organisms.
Topics: Amikacin; Aztreonam; Drug Synergism; Gram-Negative Bacteria; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1986 |
Control of emergence of multi-resistant gram-negative bacilli by exclusive use of amikacin.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Cross Infection; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Klebsiella; Microbial Sensitivity Tests; Prospective Studies; Pseudomonas aeruginosa; Time Factors; Tobramycin | 1986 |
Serum bactericidal activity and killing rate for volunteers receiving imipenem, imipenem plus amikacin, and ceftazidime plus amikacin against Pseudomonas aeruginosa.
Topics: Amikacin; Ceftazidime; Drug Interactions; Female; Humans; Imipenem; Kanamycin; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Thienamycins | 1986 |
Characterization of impermeability variants of Pseudomonas aeruginosa isolated during unsuccessful therapy of experimental endocarditis.
Topics: Amikacin; Animals; Cell Membrane Permeability; Drug Resistance, Microbial; Endocarditis, Bacterial; Freeze Fracturing; Gentamicins; Kanamycin; Microscopy, Electron; Microscopy, Electron, Scanning; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Virulence | 1987 |
Effects of medium and inoculum variations on screening for high-level aminoglycoside resistance in Enterococcus faecalis.
Topics: Amikacin; Anti-Bacterial Agents; Culture Media; Drug Resistance, Microbial; Drug Synergism; Enterococcus faecalis; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Penicillins; Predictive Value of Tests; Streptomycin; Time Factors; Tobramycin | 1988 |
High-content aminoglycoside disks for determining aminoglycoside-penicillin synergy against Enterococcus faecalis.
Topics: Amikacin; Anti-Bacterial Agents; Culture Media; Drug Synergism; Enterococcus faecalis; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Penicillins; Streptomycin; Tobramycin | 1988 |
[Comparative activity of habekacin and 4 other aminoglycosides against gram-negative bacilli. Evolution of resistance].
Topics: Acinetobacter; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Dibekacin; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Netilmicin; Pseudomonas aeruginosa; Tobramycin | 1988 |
In vitro activity of enoxacin compared with norfloxacin and amikacin.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Calcium; Drug Interactions; Drug Resistance, Microbial; Enoxacin; Enterobacteriaceae; Enterococcus faecalis; Kanamycin; Magnesium; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Pseudomonas aeruginosa; Staphylococcus aureus | 1985 |
Comparative uptake of gentamicin, netilmicin, and amikacin in the guinea pig cochlea and vestibule.
Topics: Amikacin; Animals; Cochlea; Gentamicins; Guinea Pigs; Kanamycin; Kinetics; Netilmicin; Vestibule, Labyrinth | 1986 |
[Diffusion of amikacin in the lungs].
Topics: Amikacin; Dibekacin; Diffusion; Humans; Kanamycin; Kinetics; Lung; Netilmicin; Tobramycin | 1986 |
Plasmid-encoded amikacin resistance in multiresistant strains of Klebsiella pneumoniae isolated from neonates with meningitis.
Topics: Acetyltransferases; Amikacin; Ampicillin; Cerebrospinal Fluid; Conjugation, Genetic; Cross Infection; DNA, Bacterial; Electrophoresis, Agar Gel; Escherichia coli; Humans; Infant, Newborn; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Meningitis; Nucleic Acid Hybridization; Penicillin Resistance; R Factors; Tobramycin | 1986 |
Amikacin-induced alterations in the structure of gram-negative bacilli.
Topics: Amikacin; Escherichia coli; Gram-Negative Bacteria; Kanamycin | 1986 |
Successful treatment of a pancreatic Nocardia asteroides abscess with amikacin and surgical drainage.
Topics: Abscess; Aged; Amikacin; Drainage; Humans; Kanamycin; Male; Nocardia asteroides; Nocardia Infections; Pancreatic Diseases | 1986 |
Correlation of antibiotic synergy in vitro and in vivo: use of an animal model of neutropenic gram-negative sepsis.
Topics: Agranulocytosis; Amikacin; Animals; Drug Synergism; Drug Therapy, Combination; Enterobacteriaceae Infections; Imipenem; Kanamycin; Kinetics; Klebsiella Infections; Microbial Sensitivity Tests; Neutropenia; Pseudomonas Infections; Rats; Sepsis; Serratia marcescens; Thienamycins | 1986 |
Efficacy of single-agent therapy with azlocillin, ticarcillin, and amikacin and beta-lactam/amikacin combinations for treatment of Pseudomonas aeruginosa bacteremia in granulocytopenic rats.
Topics: Agranulocytosis; Amikacin; Animals; Azlocillin; Drug Therapy, Combination; Female; Kanamycin; Microbial Sensitivity Tests; Neutropenia; Penicillin Resistance; Penicillins; Pseudomonas Infections; Rats; Rats, Inbred Strains; Sepsis; Ticarcillin | 1986 |
Empirical antimicrobial therapy with Timentin plus amikacin in febrile granulocytopenic cancer patients.
Topics: Adult; Aged; Agranulocytosis; Amikacin; Bacteria; Bacterial Infections; Clavulanic Acids; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Fever; Humans; Kanamycin; Male; Middle Aged; Neoplasms; Penicillin Resistance; Penicillins; Sepsis; Ticarcillin | 1986 |
Amikacin synergism with beta-lactam antibiotics against selected nosocomial pathogens.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; beta-Lactams; Cross Infection; Drug Resistance, Microbial; Drug Synergism; Gram-Negative Bacteria; Humans; Kanamycin; Microbial Sensitivity Tests | 1986 |
Aminoglycoside antibiotics. 6. Chemical reactions of aminoglycosides with disodium carbenicillin.
Topics: Acylation; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Carbenicillin; Chromatography, Thin Layer; Gentamicins; Humans; Kanamycin; Magnetic Resonance Spectroscopy; Tobramycin | 1986 |
[Rapid microdetermination of 2 aminoglycosides by high-performance liquid chromatography in the plasma, bile and urine. Correlation of high-performance liquid chromatography and fluorescence polarization for plasma assays].
Topics: Amikacin; Bile; Chromatography, High Pressure Liquid; Dibekacin; Fluorescence Polarization; Humans; Kanamycin; Microchemistry | 1986 |
Construction and characterization of new cloning vectors derived from Streptomyces griseobrunneus plasmid pBT1 and containing amikacin and sulfomycin resistance genes.
Topics: Amikacin; Anti-Bacterial Agents; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Microbial; Genes, Bacterial; Genetic Vectors; Kanamycin; Nucleic Acid Hybridization; Peptide Biosynthesis; Peptides; Plasmids; Streptomyces; Thiostrepton | 1986 |
In vitro inactivation of aminoglycosides by apalcillin.
Topics: Amikacin; Ampicillin; Drug Combinations; Drug Stability; Gentamicins; Kanamycin; Naphthyridines; Netilmicin; Time Factors; Tobramycin | 1986 |
Treatment of snakes.
Topics: Amikacin; Animals; Kanamycin; Snakes; Temperature | 1986 |
Combination antibiotic therapy in pediatrics.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Cystic Fibrosis; Drug Synergism; Drug Therapy, Combination; Humans; Immunologic Deficiency Syndromes; Infant; Infant, Newborn; Kanamycin; Lactams; Neutropenia; Peritoneal Dialysis, Continuous Ambulatory; Pseudomonas Infections; Risk | 1986 |
Upper and lower urinary tract infections: amikacin's role in managing surgical complications.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Cross Infection; Drug Therapy, Combination; Humans; Kanamycin; Postoperative Complications; Premedication; Risk; Surgical Wound Infection; Urinary Catheterization; Urinary Tract Infections | 1986 |
Antibiotics delivered by an implantable drug pump. A new application for treating osteomyelitis.
Topics: Adult; Amikacin; Anti-Bacterial Agents; Debridement; Drug Implants; Drug Therapy, Combination; Gram-Negative Bacteria; Hearing; Humans; Kanamycin; Kidney; Length of Stay; Middle Aged; Osteomyelitis; Staphylococcal Infections; Time Factors | 1986 |
[Anti-tuberculous activity of amikacin].
Topics: Amikacin; Animals; Antitubercular Agents; Drug Synergism; Drug Therapy, Combination; Kanamycin; Male; Mice; Tuberculosis, Pulmonary | 1986 |
In vitro aminoglycoside resistance of gram-negative bacilli and staphylococci isolated from blood in Sweden 1980-1984.
Topics: Amikacin; Aminoglycosides; Drug Resistance, Microbial; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Microbial Sensitivity Tests; Netilmicin; Staphylococcus; Sweden; Tobramycin | 1986 |
In vitro amikacin sensitivity testing.
Topics: Amikacin; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Streptomycin | 1986 |
Frequency of aminoglycoside 6'-N-acetyltransferase among Serratia species during increased use of amikacin in the hospital.
Topics: Acetyltransferases; Amikacin; DNA, Bacterial; Drug Utilization; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Serratia; Time Factors; Tobramycin | 1986 |
Treatment of cerebrospinal fluid leaks and gram-negative bacillary meningitis with large doses of intrathecal amikacin and systemic antibiotics.
Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Cerebrospinal Fluid; Cerebrospinal Fluid Rhinorrhea; Gram-Negative Bacteria; Humans; Injections, Spinal; Kanamycin; Male; Meningitis; Middle Aged; Spinal Cord Diseases | 1986 |
Antibacterial activity and ototoxicity in guinea pigs, and nephrotoxicity in rats of arbekacin.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Bacterial Infections; Dibekacin; Drug Resistance, Microbial; Ear, Inner; Guinea Pigs; Injections, Intramuscular; Kanamycin; Kidney; Male; Rats; Rats, Inbred Strains; Reflex; Structure-Activity Relationship | 1986 |
Protective activity of habekacin and four other aminoglycosides in mouse septicaemia caused by Enterobacteriaceae.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Dibekacin; Enterobacteriaceae Infections; Female; Gentamicins; Kanamycin; Male; Mice; Microbial Sensitivity Tests; Sepsis; Tobramycin | 1986 |
In vitro susceptibility of gram negative bacteria to amikacin and its comparison with three other aminoglycoside antibiotics.
Topics: Amikacin; Drug Resistance, Microbial; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Microbial Sensitivity Tests; Paromomycin | 1985 |
Three-year experience with amikacin sulfate as an exclusive surgical aminoglycoside in a large acute-care hospital.
Topics: Abdomen; Abscess; Amikacin; Ampicillin; Cefazolin; Clindamycin; Cross Infection; Drug Administration Schedule; Drug Therapy, Combination; Drug Utilization; Gentamicins; Gram-Negative Bacteria; Hospital Bed Capacity, 500 and over; Hospitals, Veterans; Humans; Kanamycin; Male; Middle Aged; Minnesota; Penicillin Resistance; Peritonitis; Postoperative Complications; Premedication; Surgical Wound Infection | 1985 |
Bacteriological efficacy of nafcillin and vancomycin alone or combined with rifampicin or amikacin in experimental meningitis due to methicillin-susceptible or -resistant Staphylococcus aureus.
Topics: Amikacin; Animals; Child; Drug Therapy, Combination; Humans; Kanamycin; Kinetics; Meningitis; Methicillin; Nafcillin; Penicillin Resistance; Rabbits; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 1985 |
Mezlocillin, ceftizoxime, and amikacin alone and in combination against six Enterobacteriaceae in a neutropenic site in rabbits.
Topics: Agranulocytosis; Amikacin; Animals; Cefotaxime; Ceftizoxime; Drug Combinations; Enterobacteriaceae; Female; Hydrogen-Ion Concentration; Kanamycin; Mezlocillin; Microbial Sensitivity Tests; Neutropenia; Rabbits | 1985 |
The predictive value of urinary N-acetyl-beta-D-glucosaminidase in evaluating aminoglycoside nephrotoxicity.
Topics: Acetylglucosaminidase; Adult; Aged; Amikacin; Aminoglycosides; Female; Gentamicins; Hexosaminidases; Humans; Kanamycin; Kidney; Kidney Diseases; Lupus Erythematosus, Systemic; Male; Middle Aged | 1985 |
Serum bactericidal activity as a therapeutic guide in severely granulocytopenic patients with gram-negative septicemia.
Topics: Agranulocytosis; Amikacin; Anti-Bacterial Agents; Ceftazidime; Drug Combinations; Drug Synergism; Gram-Negative Bacteria; Humans; Kanamycin; Leukemia; Microbial Sensitivity Tests; Penicillins; Sepsis; Ticarcillin | 1985 |
[Chronotoxicity of amikacin].
Topics: Amikacin; Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Kanamycin; Mice; Seasons | 1985 |
[New effective therapy of systemic infection with Nocardia asteroides].
Topics: Amikacin; Amoxicillin; Bronchoscopy; Clavulanic Acids; Electrocardiography; Humans; Kanamycin; Lung; Male; Middle Aged; Nocardia asteroides; Nocardia Infections | 1985 |
Efficacy of amikacin and ceftazidime in experimental aortic valve endocarditis due to Pseudomonas aeruginosa.
Topics: Amikacin; Animals; Aortic Valve; Blood Bactericidal Activity; Ceftazidime; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Endocarditis, Bacterial; Female; Heart Valve Diseases; Kanamycin; Microbial Sensitivity Tests; Pseudomonas Infections; Rabbits | 1985 |
[Mycetomas with pulmonary dissemination].
Topics: Administration, Oral; Adult; Amikacin; Drug Combinations; Drug Therapy, Combination; Humans; Injections, Intravenous; Kanamycin; Lung Diseases, Fungal; Male; Middle Aged; Mycetoma; Nocardia Infections; Radiography; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1985 |
Amikacin-resistant gram-negative bacilli: correlation of occurrence with amikacin use.
Topics: Acetyltransferases; Amikacin; Bacterial Infections; Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Gram-Negative Bacteria; Humans; Kanamycin; New York; Pseudomonas aeruginosa; Pseudomonas Infections; R Factors | 1985 |
Transferable amikacin and cefamandole resistance: Pseudomonas maltophilia and Acinetobacter strains as possible reservoirs of R plasmids.
Topics: Acinetobacter; Amikacin; Cefamandole; Enterobacteriaceae; Escherichia coli; Kanamycin; Pseudomonas; Pseudomonas aeruginosa; R Factors; Salmonella typhimurium | 1985 |
Overview of first-line amikacin therapy for urologic infections.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Drug Therapy, Combination; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Kanamycin; Kidney Diseases; Lactams; Sepsis; Urinary Tract Infections | 1985 |
Antagonistic effect of penicillin-amikacin combinations against enterococci.
Topics: Amikacin; Bacterial Proteins; Bacteriolysis; Carrier Proteins; Drug Combinations; Drug Synergism; Enterococcus faecalis; Hexosyltransferases; Humans; Kanamycin; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Phosphorylation; Protein Binding; Ribosomal Proteins; Time Factors | 1985 |
Interaction of third generation cephalosporins combined with amikacin against Pseudomonas aeruginosa.
Topics: Amikacin; Cefoperazone; Cefotaxime; Ceftizoxime; Cephalosporins; Drug Synergism; Kanamycin; Microbial Sensitivity Tests; Moxalactam; Pseudomonas aeruginosa | 1985 |
Interaction of third generation cephalosporins combined with amikacin against Pseudomonas aeruginosa.
Topics: Amikacin; Cephalosporins; Drug Synergism; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1985 |
Aminoglycosides and ampicillin to newborn infants. Kinetics and dosage calculations.
Topics: Amikacin; Amino Acids; Ampicillin; Bacterial Infections; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Stability; Drug Therapy, Combination; Gentamicins; Humans; Infant, Newborn; Kanamycin; Kinetics; Parenteral Nutrition; Prospective Studies | 1985 |
Amikacin + ceftazidime therapy of experimental right-sided Pseudomonas aeruginosa endocarditis in rabbits.
Topics: Amikacin; Animals; Ceftazidime; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Kanamycin; Microbial Sensitivity Tests; Myocardium; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits | 1985 |
Clinical efficacy of a synergistic combination of cefotaxime and amikacin against multiresistant Pseudomonas and Serratia infections.
Topics: Aged; Amikacin; Aminoglycosides; Cefotaxime; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Enterobacteriaceae Infections; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Serratia marcescens | 1985 |
Factors associated with nephrotoxicity and clinical outcome in patients receiving amikacin.
Topics: Adult; Aged; Amikacin; Bacterial Infections; Creatinine; Female; Humans; Kanamycin; Kidney Diseases; Kinetics; Male; Microbial Sensitivity Tests; Middle Aged | 1986 |
Neonatal septicemia due to Pseudomonas aeruginosa.
Topics: Adult; Amikacin; Ampicillin; Female; Humans; Infant, Newborn; Kanamycin; Male; Pregnancy; Pseudomonas Infections; Sepsis; Ticarcillin | 1986 |
Pharmacokinetics of amikacin in pony foals after a single intramuscular injection.
Topics: Amikacin; Animals; Animals, Newborn; Half-Life; Horses; Injections, Intramuscular; Kanamycin; Kinetics; Metabolic Clearance Rate | 1986 |
Clinical and microbiologic consequences of amikacin use during a 42-month period.
Topics: Age Factors; Aged; Amikacin; Bacterial Infections; Catheterization; Drug Resistance, Microbial; Gentamicins; Gram-Negative Bacteria; Hospital Bed Capacity, 500 and over; Hospitalization; Hospitals, Veterans; Humans; Kanamycin; Microbial Sensitivity Tests; Middle Aged; Tennessee; Tobramycin | 1986 |
Compatibility of furosemide with aminoglycoside admixtures.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Chemical Phenomena; Chemistry, Physical; Drug Combinations; Drug Incompatibility; Furosemide; Gentamicins; Hydrogen-Ion Concentration; Kanamycin; Netilmicin; Tobramycin | 1985 |
Amikacin concentrations in serum following intraoperative irrigation of the pleura and peritoneum.
Topics: Absorption; Adult; Amikacin; Humans; Inhalation; Intraoperative Period; Kanamycin; Middle Aged; Peritoneum; Pleura; Therapeutic Irrigation | 1985 |
Gentamicin, tobramycin, amikacin, and netilmicin levels in tears following intravenous administration.
Topics: Adult; Aged; Amikacin; Bacterial Infections; Female; Gentamicins; Humans; Infusions, Parenteral; Kanamycin; Keratitis; Male; Microbial Sensitivity Tests; Middle Aged; Netilmicin; Tears; Tobramycin | 1985 |
Low ototoxicity and its mechanism of netilmicin.
Topics: Amikacin; Aminoglycosides; Animals; Dibekacin; Gentamicins; Hair Cells, Auditory; Kanamycin; Kidney; Labyrinth Diseases; Nerve Degeneration; Netilmicin; Rabbits | 1985 |
The International Standard for Amikacin.
Topics: Amikacin; Diffusion; Kanamycin; Microbial Sensitivity Tests; Nephelometry and Turbidimetry; Reference Standards; United States | 1985 |
Effect of peritoneal dialysis on serum concentrations of three drugs commonly used in pediatric patients.
Topics: Amikacin; Cefazolin; Female; Humans; Infant; Infant, Newborn; Kanamycin; Male; Metabolic Clearance Rate; Peritoneal Dialysis; Phenobarbital | 1985 |
Chemical modification of amikacin at C-4'' with inversion of configuration.
Topics: Amikacin; Binding Sites; Kanamycin; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests | 1985 |
Evaluation of the resistance mechanisms of gentamicin-resistant Gram-negative bacilli and their susceptibility to tobramycin, netilmicin and amikacin.
Topics: Amikacin; Drug Resistance, Microbial; Gentamicins; Gram-Negative Bacteria; Kanamycin; Microbial Sensitivity Tests; Netilmicin; Tobramycin | 1985 |
[Empiric therapy with piperacillin plus amikacin for febrile patients with cancer--with emphasis on granulocytopenia].
Topics: Acute Disease; Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Kanamycin; Leukemia; Leukocyte Count; Lymphoma; Male; Middle Aged; Neoplasms; Piperacillin | 1985 |
Effect of pentobarbital anesthesia on amikacin concentrations in plasma and perilymph and evaluation of multiple sampling in perilymph of guinea pigs.
Topics: Amikacin; Anesthesia; Animals; Drug Interactions; Guinea Pigs; Infusions, Parenteral; Kanamycin; Kinetics; Labyrinthine Fluids; Male; Pentobarbital; Perilymph | 1985 |
Pharmacokinetics of amikacin in the horse following intravenous and intramuscular administration.
Topics: Amikacin; Animals; Body Fluids; Female; Horses; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Kinetics; Male; Synovial Fluid | 1985 |
Aminoglycoside resistance in gram-negative bacilli during increased amikacin use. Comparison of experience in 14 United States hospitals with experience in the Minneapolis Veterans Administration Medical Center.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Utilization; Gentamicins; Gram-Negative Bacteria; Hospitals, Veterans; Humans; Kanamycin; Minnesota; Time Factors; Tobramycin; United States | 1985 |
Treatment of pediatric infections with amikacin as first-line aminoglycoside.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Chicago; Child; Drug Resistance, Microbial; Drug Synergism; Drug Utilization; Gram-Negative Bacteria; Hospitals, Pediatric; Humans; Infant, Newborn; Kanamycin; Microbial Sensitivity Tests; Neutropenia; Pediatrics; Pseudomonas; Staphylococcus | 1985 |
Antibiotic treatment of complicated urologic infections. Six selected case studies.
Topics: Adult; Aged; Amikacin; Combined Modality Therapy; Diabetes Mellitus, Type 1; Female; Gangrene; Genital Diseases, Male; Humans; Ileum; Kanamycin; Kidney; Male; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Scrotum; Urinary Calculi; Urinary Diversion; Urinary Fistula; Urinary Tract Infections | 1985 |
Comparative toxicity of intravitreal aminoglycoside antibiotics.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Basement Membrane; Electroretinography; Gentamicins; Injections; Kanamycin; Microscopy, Electron; Netilmicin; Pigment Epithelium of Eye; Rabbits; Retina; Rod Cell Outer Segment; Tobramycin; Vitreous Body | 1985 |
[Experimental study of the pharmacological properties of amikacin].
Topics: Alanine Transaminase; Alkaline Phosphatase; Amikacin; Animals; Aspartate Aminotransferases; Bilirubin; Blood Cell Count; Blood Urea Nitrogen; Cats; Granulocytes; Guinea Pigs; Kanamycin; Rabbits; Rats | 1985 |
Amikacin therapy for Pseudomonas cellulitis in an Amazon parrot.
Topics: Amikacin; Animals; Bird Diseases; Cellulitis; Kanamycin; Parrots; Pseudomonas Infections; Psittaciformes | 1985 |
Clinical pharmacokinetics of amikacin in dogs.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria; Dogs; Drug Resistance, Microbial; Half-Life; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Kanamycin; Species Specificity | 1985 |
Motility and fertility of frozen bull spermatozoa in tris-yolk and milk extenders containing amikacin sulfate.
Topics: Amikacin; Animals; Cattle; Egg Yolk; Fertility; Freezing; Kanamycin; Male; Milk; Semen Preservation; Sperm Count; Sperm Motility; Spermatozoa; Tromethamine | 1985 |
[Study of the local use of amikacin].
Topics: Adult; Aged; Amikacin; Anti-Infective Agents, Urinary; Catheters, Indwelling; Drug Evaluation; Female; Humans; Kanamycin; Male; Middle Aged; Urinary Tract Infections | 1985 |
Measurement of amikacin in serum by a latex agglutination inhibition test.
Topics: Amikacin; Humans; Infant, Newborn; Kanamycin; Latex Fixation Tests; Radioimmunoassay | 1985 |
Aminoglycoside antibiotics and lysosomal enzymes of human tears.
Topics: Acetylglucosaminidase; Acid Phosphatase; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Depression, Chemical; Dibekacin; Erythromycin; Gentamicins; Hexosaminidases; Humans; Kanamycin; Muramidase; Sulbenicillin; Tears; Tobramycin | 1985 |
Otoconia and neural junctions of type I hair cells in amikacin-treated guinea pigs presenting saccular acoustic responses.
Topics: Amikacin; Animals; Evoked Potentials, Auditory; Guinea Pigs; Hair Cells, Auditory; Hair Cells, Auditory, Inner; Kanamycin; Microscopy, Electron; Microscopy, Electron, Scanning; Otolithic Membrane; Saccule and Utricle; Synapses | 1985 |
Nephrotoxicity of aminoglycosides in young and adult rats.
Topics: Age Factors; Amikacin; Animals; Biological Transport, Active; Body Weight; Gentamicins; Glomerular Filtration Rate; Kanamycin; Kidney; Kidney Tubules, Proximal; Male; Organ Size; Rats; Rats, Inbred Strains | 1985 |
Effects of ambient temperature on the half-life and dosage regimen of amikacin in the gopher snake.
Topics: Amikacin; Animals; Body Temperature; Dose-Response Relationship, Drug; Female; Half-Life; Kanamycin; Male; Metabolic Clearance Rate; Snakes; Temperature | 1985 |
[Clinical evaluation of amikacin by intravenous drip infusion for infections in the field of internal medicine].
Topics: Acinetobacter Infections; Adult; Aged; Amikacin; Bacterial Infections; Cystitis; Female; Humans; Infusions, Parenteral; Kanamycin; Leukemia; Male; Middle Aged; Pneumonia; Respiratory Tract Infections; Sepsis | 1985 |
[Our experience in the treatment of peritonitis in ambulatory chronic peritoneal dialysis with mezlocillin and amikacin].
Topics: Adolescent; Amikacin; Child; Drug Therapy, Combination; Humans; Kanamycin; Male; Mezlocillin; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis | 1985 |
[Ototoxic effect of amikacin].
Topics: Adult; Amikacin; Audiometry, Pure-Tone; Female; Follow-Up Studies; Hearing Loss, Sudden; Humans; Kanamycin; Male; Middle Aged | 1985 |
[Experimental study of the antibacterial activity and chemotherapeutic effectiveness of amikacin sulfate].
Topics: Amikacin; Animals; Bacteria; Bacterial Infections; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Kanamycin; Mice; Microbial Sensitivity Tests | 1985 |
Comparison of penicillin and vancomycin, individually and in combination with gentamicin and amikacin, in the treatment of experimental endocarditis induced by nutritionally variant streptococci.
Topics: Amikacin; Animals; Endocarditis, Bacterial; Female; Gentamicins; Kanamycin; Penicillins; Rabbits; Streptococcal Infections; Time Factors; Vancomycin | 1985 |
Amikacin (BB-K8) treatment of multiple-drug resistant Proteus infections.
Topics: Adult; Aged; Amikacin; Drug Resistance, Microbial; Female; Humans; Kanamycin; Male; Middle Aged; Proteus Infections | 1974 |
Pharmacology of amikacin in humans.
Topics: Amikacin; Humans; Kanamycin; Kinetics | 1974 |
[Ceftriaxone by systemic route combined with amikacin by intraventricular route in the treatment of ventriculitis in children with hydrocephalus].
Topics: Amikacin; Cefotaxime; Ceftriaxone; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Drug Therapy, Combination; Encephalitis; Humans; Hydrocephalus; Injections, Intraventricular; Kanamycin | 1984 |
[Combined effect of cefotaxime and aminoglycoside antibiotics on Pseudomonas strains and group D streptococci].
Topics: Amikacin; Cefotaxime; Drug Synergism; Enterococcus faecalis; Gentamicins; In Vitro Techniques; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Sisomicin | 1984 |
Urinary excretion of N-acetyl-beta-D-glucosaminidase and alanine aminopeptidase in patients receiving amikacin or cis-platinum.
Topics: Acetylglucosaminidase; Adult; Aged; Amikacin; Aminopeptidases; CD13 Antigens; Cisplatin; Creatinine; Female; Hexosaminidases; Humans; Kanamycin; Kidney; Kinetics; Male; Middle Aged; Reference Values | 1981 |
[Serial measurement of serum levels of amikacin. Value in therapy].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Female; Humans; Kanamycin; Kidney Diseases; Male; Middle Aged; Time Factors | 1981 |
[Kinetics of multiple-dose amikacin in the newborn infant].
Topics: Amikacin; Bacterial Infections; Female; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Kanamycin; Kinetics; Pregnancy | 1981 |
Cefoxitin, amikacin, and Pseudomonas aeruginosa resistance.
Topics: Amikacin; Aminoglycosides; Cefoxitin; Drug Resistance, Microbial; Humans; Kanamycin; Pseudomonas aeruginosa; Spain | 1982 |
Effect of amikacin and gentamicin on urinary enzyme excretion.
Topics: Adolescent; Adult; Aged; Amikacin; Female; gamma-Glutamyltransferase; Gentamicins; Humans; Kanamycin; Leucyl Aminopeptidase; Male; Middle Aged | 1983 |
Quantitative histophotometry analysing significant inductive and alterative effects of aminoglycoside application (gentamicin, tobramycin, amikacin) upon tubular kidney proteins.
Topics: Alkaline Phosphatase; Amikacin; Aminoglycosides; Aminopeptidases; Animals; Anti-Bacterial Agents; CD13 Antigens; Computers; Enzyme Induction; Gentamicins; Glucuronidase; Kanamycin; Kidney Tubules, Proximal; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Staining and Labeling; Tobramycin | 1982 |
Amikacin in the treatment of pulmonary tuberculosis.
Topics: Adult; Amikacin; Capreomycin; Drug Resistance, Microbial; Female; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Streptomycin; Tuberculosis, Pulmonary | 1983 |
[Clinical study on effect of local administration of amikacin for complicated cystitis accompanied by residual urine].
Topics: Adult; Aged; Amikacin; Cystitis; Female; Humans; Kanamycin; Male; Middle Aged; Prostatic Hyperplasia; Urinary Bladder; Urinary Bladder Neoplasms; Urination Disorders | 1984 |
In vitro susceptibility of cephalothin-resistant Enterobacteriaceae and Pseudomonas aeruginosa to Amikacin and selected new beta-lactam agents.
Topics: Amikacin; Anti-Bacterial Agents; beta-Lactams; Cefoxitin; Cephalothin; Cephamycins; Drug Resistance, Microbial; Enterobacteriaceae; Kanamycin; Microbial Sensitivity Tests; Moxalactam; Pseudomonas aeruginosa | 1982 |
Serum bactericidal activity of ceftazidime and cefoperazone alone or in combination with amikacin against Pseudomonas aeruginosa and Klebsiella pneumoniae.
Topics: Amikacin; Anti-Bacterial Agents; Blood Bactericidal Activity; Cefoperazone; Ceftazidime; Cephalosporins; Drug Synergism; Humans; Kanamycin; Klebsiella pneumoniae; Pseudomonas aeruginosa | 1983 |
[Spacing doses of amikacin in renal failure patients. Calculation based on blood creatinine expressed in micromoles].
Topics: Amikacin; Creatinine; Humans; Kanamycin; Kidney Diseases; Osmolar Concentration | 1983 |
Moxalactam/amikacin versus ticarcillin/amikacin in granulocytopenic patients.
Topics: Agranulocytosis; Amikacin; Cephalosporins; Cephamycins; Drug Therapy, Combination; Humans; Infections; Kanamycin; Moxalactam; Penicillins; Ticarcillin | 1983 |
Early synergistic interaction between semisynthetic penicillins and aminoglycosidic aminocyclitols against Enterobacteriaceae.
Topics: Amikacin; Aminoglycosides; Drug Synergism; Enterobacteriaceae; Gentamicins; Kanamycin; Penicillins; Piperacillin | 1983 |
[Intracisternal concentrations of vancomycin and amikacin after lumbar injections].
Topics: Amikacin; Humans; Injections, Spinal; Kanamycin; Male; Middle Aged; Vancomycin | 1983 |
Cefotaxime and amikacin: results of in vitro and in vivo studies against Gram-negative bacteria and Staphylococcus aureus. EORTC International Antimicrobial Therapy Project Group.
Topics: Amikacin; Animals; Bacteria; Bacterial Infections; Cefotaxime; Cephalosporins; Drug Synergism; Humans; Kanamycin; Mice; Staphylococcus aureus | 1980 |
Activity of cefotaxime-aminoglycoside combinations against aminoglycoside-resistant Pseudomonas.
Topics: Amikacin; Anti-Bacterial Agents; Cefotaxime; Cephalosporins; Drug Resistance, Microbial; Drug Synergism; Gentamicins; Humans; Kanamycin; Pseudomonas aeruginosa; Tobramycin | 1980 |
Plasmid-mediated resistance to aminocyclitol antibiotics in group D streptococci.
Topics: Acetyltransferases; Amikacin; Enterococcus faecalis; Gentamicins; Kanamycin; Kanamycin Kinase; Nucleotidyltransferases; Phosphotransferases; R Factors; Structure-Activity Relationship | 1980 |
[Combined cefotaxime-amikacin treatment of infectious episodes in acute leukaemia patients with therapeutically-induced bone marrow aplasia (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Cefotaxime; Cephalosporins; Drug Therapy, Combination; Humans; Kanamycin; Leukemia; Middle Aged | 1981 |
Resistance to antibiotic synergism in Streptococcus faecalis: further studies with amikacin and with a new amikacin derivative, 4'-deoxy, 6'-N-methylamikacin.
Topics: Amikacin; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Synergism; Enterococcus faecalis; Kanamycin; Kanamycin Kinase; Microbial Sensitivity Tests; Phosphotransferases | 1981 |
New plasmid-mediated aminoglycoside adenylyltransferase of broad substrate range that adenylylates amikacin.
Topics: Amikacin; Aminoglycosides; Conjugation, Genetic; Cross Infection; Gentamicins; Humans; Hydrogen-Ion Concentration; Kanamycin; Klebsiella pneumoniae; Molecular Weight; Nucleotidyltransferases; Plasmids; Substrate Specificity | 1981 |
Aminoglycoside phosphotransferase-II-mediated amikacin resistance in Escherichia coli.
Topics: Amikacin; Bacterial Proteins; Cell-Free System; Conjugation, Genetic; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Kanamycin Kinase; Microbial Sensitivity Tests; Phosphorylation; Phosphotransferases; Plasmids | 1981 |
Decreased susceptibility to 4'-deoxy-6'-N-methylamikacin (BB-K311) conferred by a mutant plasmid in Escherichia coli.
Topics: Amikacin; Escherichia coli; Genes, Bacterial; Kanamycin; Kanamycin Kinase; Mutation; Phosphotransferases; R Factors | 1982 |
Disk diffusion testing with polymyxin and amikacin for differentiation of Mycobacterium fortuitum and Mycobacterium chelonei.
Topics: Amikacin; Diffusion; Drug Resistance, Microbial; Kanamycin; Microbial Sensitivity Tests; Mycobacterium; Polymyxin B; Polymyxins | 1982 |
Amikacin resistance mediated by multiresistance transposon Tn2424.
Topics: Amikacin; Cloning, Molecular; DNA Restriction Enzymes; DNA Transposable Elements; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Microscopy, Electron; Pseudomonas aeruginosa | 1983 |
Artificial activation and degeneration of the cochlear nerve in guinea pigs.
Topics: Amikacin; Animals; Auditory Cortex; Auditory Perception; Cochlear Nerve; Electric Stimulation; Evoked Potentials, Auditory; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Nerve Degeneration; Organ of Corti; Sisomicin; Spiral Ganglion; Synaptic Transmission | 1983 |
Impairment of membrane phosphoinositide metabolism by aminoglycoside antibiotics: streptomycin, amikacin, kanamycin, dibekacin, gentamicin and neomycin.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Dibekacin; Erythrocyte Membrane; Gentamicins; Kanamycin; Neomycin; Phosphatidylinositols; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Streptomycin | 1983 |
In vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against Pseudomonas aeruginosa.
Topics: Amikacin; Cefotaxime; Ceftriaxone; Drug Synergism; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin | 1983 |
In vitro and in vivo synergy between ceftriaxone and aminoglycosides against Pseudomonas aeruginosa.
Topics: Amikacin; Animals; Cefotaxime; Ceftriaxone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gentamicins; Kanamycin; Leukopenia; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 1983 |
[Antibacterial activities of amicacin, azlocillin and cefotaxim in bronchial secretion and serum of children].
Topics: Amikacin; Anti-Infective Agents; Azlocillin; Bronchi; Cefotaxime; Child; Humans; Kanamycin; Penicillins | 1983 |
In vitro activity of newer beta-lactam agents in combination with amikacin against Pseudomonas aeruginosa, Klebsiella pneumoniae, and Serratia marcescens.
Topics: Amikacin; Anti-Bacterial Agents; Cefoperazone; Cefotaxime; Ceftazidime; Ceftizoxime; Cephalosporins; Drug Synergism; Imipenem; Kanamycin; Klebsiella pneumoniae; Microbial Sensitivity Tests; Moxalactam; Pseudomonas aeruginosa; Serratia marcescens; Thienamycins | 1983 |
Cefoperazone versus cefotaxime, plus amikacin or sisomicin, in fever and infection in hematologic granulocytopenic patients.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Anemia, Aplastic; Cefoperazone; Cefotaxime; Drug Therapy, Combination; Female; Fever; Humans; Immunosuppression Therapy; Infections; Kanamycin; Leukemia; Male; Middle Aged; Random Allocation; Sisomicin | 1984 |
Comparison of azlocillin, ceftizoxime, cefoxitin, and amikacin alone and in combination against Pseudomonas aeruginosa in a neutropenic-site rabbit model.
Topics: Agranulocytosis; Amikacin; Animals; Anti-Bacterial Agents; Azlocillin; Cefotaxime; Cefoxitin; Ceftizoxime; Disease Models, Animal; Drug Combinations; Female; Hydrogen-Ion Concentration; Kanamycin; Microbial Sensitivity Tests; Neutropenia; Penicillins; Protein Binding; Pseudomonas Infections; Rabbits | 1984 |
Enhanced in vitro bactericidal activity of amikacin or gentamicin combined with three new extended-spectrum cephalosporins against cephalothin-resistant members of the family Enterobacteriaceae.
Topics: Amikacin; Cefotaxime; Ceftazidime; Ceftizoxime; Ceftriaxone; Cephalosporins; Cephalothin; Drug Resistance, Microbial; Drug Synergism; Enterobacteriaceae; Gentamicins; Kanamycin; Time Factors | 1984 |
Synergism of imipenem and amikacin in combination with other antibiotics against Nocardia asteroides.
Topics: Amikacin; Anti-Bacterial Agents; Colony-Forming Units Assay; Drug Synergism; Imipenem; Kanamycin; Microbial Sensitivity Tests; Nocardia asteroides; Thienamycins | 1983 |
Aminoglycoside-related nephrotoxicity in the premature newborn.
Topics: Acetylglucosaminidase; Amikacin; beta 2-Microglobulin; Chloramphenicol; Creatinine; Gentamicins; Humans; Infant, Newborn; Infant, Premature; Kanamycin; Kidney Diseases; Prospective Studies; Random Allocation; Sepsis | 1984 |
Comparison of enzyme immunoassay, radioimmunoassay, and microbiologic assay for amikacin in plasma.
Topics: Amikacin; Antibody Specificity; Biological Assay; Cold Temperature; Freezing; Humans; Immunoenzyme Techniques; Kanamycin; Radioimmunoassay | 1984 |
Trimethoprim/sulfamethoxazole-resistant Nocardia asteroides causing multiple hepatic abscesses. Successful treatment with ampicillin, amikacin, and limited computed tomography-guided needle aspiration.
Topics: Amikacin; Ampicillin; Combined Modality Therapy; Drug Combinations; Drug Therapy, Combination; Humans; Kanamycin; Liver Abscess; Male; Middle Aged; Nocardia asteroides; Nocardia Infections; Penicillin Resistance; Suction; Sulfamethoxazole; Tomography, X-Ray Computed; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1984 |
Amikacin assay: correlation between rapid bioassay, enzyme immuno-assay (EMIT) and fluoro-immuno-assay (FIA).
Topics: Amikacin; Biological Assay; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Kanamycin | 1984 |
In vitro evaluation of ceftazidime (GR 20263), amikacin and sisomicin, in a model simulating serum pharmacokinetics of therapeutic doses.
Topics: Amikacin; Bacteria; Ceftazidime; Humans; In Vitro Techniques; Kanamycin; Kinetics; Models, Biological; Sisomicin | 1984 |
Successful treatment of multiresistant pseudomonas peritonitis with combination of azlocillin and amikacin.
Topics: Amikacin; Azlocillin; Female; Humans; Kanamycin; Middle Aged; Penicillin Resistance; Penicillins; Peritonitis; Pseudomonas aeruginosa; Pseudomonas Infections | 1983 |
Synergistic effect of N-formimidoyl thienamycin with gentamicin and amikacin against Streptococcus faecalis.
Topics: Amikacin; Anti-Bacterial Agents; Drug Synergism; Enterococcus faecalis; Gentamicins; Imipenem; Kanamycin; Microbial Sensitivity Tests; Thienamycins | 1983 |
Error rates associated with the use of recently proposed breakpoints for testing Pseudomonas aeruginosa versus gentamicin, tobramycin, and amikacin by the standardized disk agar diffusion test.
Topics: Amikacin; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin | 1983 |
Anti-mycobacterial activity of amikacin.
Topics: Amikacin; Animals; Diabetes Mellitus, Type 1; Guinea Pigs; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Tuberculosis, Pulmonary | 1983 |
Evaluation of the automicrobic system for susceptibility testing of Pseudomonas aeruginosa to gentamicin, tobramycin, and amikacin.
Topics: Amikacin; Evaluation Studies as Topic; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin | 1984 |
[Chemotherapy of leptospirosis--effects of tobramycin, dibekacin and amikacin on the Leptospira].
Topics: Amikacin; Dibekacin; Drug Resistance, Microbial; Humans; Kanamycin; Leptospira; Leptospirosis; Tobramycin | 1984 |
Serum bactericidal activity of aztreonam, cefoperazone, and amikacin, alone or in combination, against Escherichia coli, Klebsiella pneumoniae, Serratia marcescens, and Pseudomonas aeruginosa.
Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Bacteria; Bacteriological Techniques; Cefoperazone; Drug Therapy, Combination; Escherichia coli; Humans; Kanamycin; Klebsiella pneumoniae; Pseudomonas aeruginosa; Serratia marcescens; Time Factors | 1984 |
In vitro activities of ureidopenicillins alone and in combination with amikacin and three cephalosporin antibiotics.
Topics: Amikacin; Anti-Bacterial Agents; Azlocillin; Bacteria; Cephalosporins; Drug Interactions; Kanamycin; Mezlocillin; Microbial Sensitivity Tests; Penicillins; Pseudomonas aeruginosa | 1984 |
Bactericidal activity of ceftazidime in serum compared with that of ticarcillin combined with amikacin.
Topics: Adolescent; Adult; Amikacin; Bacteria; Blood Bactericidal Activity; Ceftazidime; Drug Combinations; Enterobacteriaceae; Humans; Kanamycin; Male; Penicillins; Pseudomonas aeruginosa; Staphylococcus aureus; Ticarcillin | 1984 |
In vitro activity of mezlocillin and azlocillin compared with that of four other penicillins and two aminoglycosides.
Topics: Amikacin; Ampicillin; Azlocillin; Bacteria; Carbenicillin; Gentamicins; Kanamycin; Mezlocillin; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Piperacillin; Ticarcillin | 1980 |
Development of an infection-resistant vascular prosthesis.
Topics: Amikacin; Animals; Aorta, Abdominal; Blood Vessel Prosthesis; Collagen; Dogs; Kanamycin; Polyethylene Terephthalates; Staphylococcal Infections; Surgical Wound Infection; Textiles | 1981 |
Different dose/effects of amikacin ototoxicity on the organ of Corti and the stria vascularis in the guinea pig.
Topics: Amikacin; Animals; Audiometry, Evoked Response; Cochlea; Dose-Response Relationship, Drug; Guinea Pigs; Kanamycin; Microscopy, Electron; Organ of Corti; Stria Vascularis; Vestibulocochlear Nerve | 1984 |
Moxalactam plus piperacillin versus moxalactam plus amikacin in febrile granulocytopenic patients.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Bacteria, Anaerobic; Bacterial Infections; Child; Drug Evaluation; Drug Therapy, Combination; Enterobacteriaceae Infections; Female; Fever; Gram-Positive Bacteria; Humans; Infusions, Parenteral; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Moxalactam; Piperacillin; Pseudomonas Infections; Random Allocation; Staphylococcal Infections | 1984 |
Amikacin sulfate in mares: pharmacokinetics and body fluid and endometrial concentrations after repeated intramuscular administration.
Topics: Amikacin; Animals; Ascitic Fluid; Body Fluids; Endometrium; Female; Horse Diseases; Horses; Injections, Intramuscular; Kanamycin; Meningitis; Pseudomonas Infections; Synovial Fluid | 1984 |
Correlation of amikacin concentrations in perilymph and plasma of continuously infused guinea pigs.
Topics: Amikacin; Animals; Guinea Pigs; Infusions, Parenteral; Kanamycin; Kinetics; Labyrinthine Fluids; Male; Perilymph; Radioimmunoassay | 1984 |
Synergistic activity in vitro of the new cephalosporin antibiotic HR 810 with gentamicin and amikacin against multiresistant pathogens.
Topics: Amikacin; Anti-Bacterial Agents; Cefpirome; Cephalosporins; Drug Resistance, Microbial; Drug Synergism; Gentamicins; Kanamycin | 1984 |
Disseminated disease due to Mycobacterium chelonei treated with amikacin and cefoxitin. Absence of killing with either agent and possible role of granulocytes in clinical response.
Topics: Adult; Amikacin; Cefoxitin; Drug Resistance, Microbial; Granulocytes; Humans; Kanamycin; Lymphoma; Male; Mycobacterium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Neutropenia; Nontuberculous Mycobacteria; Skin Diseases, Infectious | 1984 |
Colorimetric determination of gentamicin, kanamycin, tobramycin, and amikacin aminoglycosides with 2,4-dinitrofluorobenzene.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Colorimetry; Dinitrofluorobenzene; Gentamicins; Kanamycin; Nitrobenzenes; Tobramycin | 1984 |
Inactivation of netilmicin and amikacin by intact or disrupted leucocytes.
Topics: Amikacin; Gentamicins; Humans; In Vitro Techniques; Kanamycin; Leukocytes; Netilmicin; Ultrasonics | 1984 |
Early synergistic interactions between amikacin and six beta-lactam antibiotics against multiply resistant members of the family Enterobacteriaceae.
Topics: Amikacin; Anti-Bacterial Agents; beta-Lactams; Drug Resistance, Microbial; Drug Synergism; Enterobacteriaceae; Kanamycin; Microbial Sensitivity Tests | 1984 |
Influence of dose in the urinary excretion of amikacin.
Topics: Adult; Amikacin; Dose-Response Relationship, Drug; Humans; Kanamycin; Kinetics | 1984 |
[Experience in combination therapy with amikacin and cephapirin for infections complicated with acute leukemia during induction chemotherapy].
Topics: Acute Disease; Adult; Amikacin; Antineoplastic Agents; Bacterial Infections; Cephalosporins; Cephapirin; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Kanamycin; Leukemia; Male; Middle Aged | 1984 |
[Amikacin-induced hearing loss in patients treated with repeated hemodialysis].
Topics: Adult; Amikacin; Endocarditis, Bacterial; Female; Hearing Loss; Hearing Loss, Bilateral; Humans; Kanamycin; Kidney Failure, Chronic; Male; Middle Aged; Pneumonia; Renal Dialysis | 1984 |
[Amikacin concentration in the severely obstructed urinary tract].
Topics: Adult; Amikacin; Female; Humans; Infusions, Parenteral; Kanamycin; Male; Middle Aged; Time Factors; Ureteral Obstruction | 1984 |
Comparative study of cefoperazone and amikacin.
Topics: Amikacin; Bacteria; Cefoperazone; Humans; Kanamycin; Microbial Sensitivity Tests; Surgical Wound Infection | 1984 |
Effect of 'high-dose' amikacin in children.
Topics: Adolescent; Amikacin; Bacterial Infections; Child; Child, Preschool; Creatinine; Deafness; Hearing; Hearing Loss, Bilateral; Humans; Infant; Kanamycin; Kidney; Time Factors | 1984 |
[Penetration of amikacin into the anterior chamber of the human eye].
Topics: Aged; Amikacin; Anterior Chamber; Aqueous Humor; Bacterial Infections; Conjunctiva; Eye Diseases; Female; Humans; Injections; Injections, Intravenous; Kanamycin; Kinetics; Male; Middle Aged | 1984 |
The acetylation of 6'-amino group of amikacin by a new enzyme prepared from serratia sp.
Topics: Acetylation; Acetyltransferases; Amikacin; Animals; Kanamycin; Male; Mice; Mice, Inbred ICR; Serratia | 1984 |
In vitro and in vivo interactions of recent cephalosporins with gentamicin and amikacin.
Topics: Adult; Aged; Amikacin; Cephalosporins; Drug Interactions; Female; Gentamicins; Humans; Kanamycin; Male; Middle Aged | 1984 |
In vitro activity of aztreonam in combination with newer beta-lactams and amikacin against multiply resistant gram-negative bacilli.
Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Drug Resistance, Microbial; Drug Synergism; Gram-Negative Bacteria; Humans; Kanamycin; Microbial Sensitivity Tests | 1984 |
The 6'-amidine derivatives of amikacin and dibekacin.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Dibekacin; Kanamycin; Microbial Sensitivity Tests; Species Specificity; Structure-Activity Relationship | 1984 |
In vitro activities of aztreonam, piperacillin, and ticarcillin combined with amikacin against amikacin-resistant Pseudomonas aeruginosa and P. cepacia isolates from children with cystic fibrosis.
Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Child; Cystic Fibrosis; Drug Therapy, Combination; Humans; Kanamycin; Penicillin Resistance; Piperacillin; Pseudomonas Infections; Ticarcillin | 1984 |
[Antibacterial stability of amikacin in infusional solutions].
Topics: Amikacin; Drug Stability; Infusions, Parenteral; Kanamycin; Solutions; Temperature | 1983 |
Increase of amikacin half-life during therapy in patients with renal insufficiency.
Topics: Adult; Amikacin; Creatinine; Female; Half-Life; Humans; Kanamycin; Kidney Diseases; Male; Middle Aged | 1983 |
Evaluation of cochlear toxicity of aminoglycoside antibiotics in guinea pigs by scanning electron microscopy.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Cochlea; Dibekacin; Gentamicins; Guinea Pigs; Kanamycin; Ribostamycin; Tobramycin | 1983 |
[In vitro susceptibility of Mycobacterium marinum to amikacin sulfate].
Topics: Amikacin; Drug Resistance, Microbial; Kanamycin; Mycobacterium | 1983 |
Determination of amikacin in serum by high-performance liquid chromatography with ultraviolet detection.
Topics: Amikacin; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Kanamycin; Spectrophotometry, Ultraviolet | 1983 |
[Sulbenicillin and amikacin for febrile patients with cancer--with special reference to granulocytopenia].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Drug Therapy, Combination; Female; Fever; Humans; Kanamycin; Male; Middle Aged; Neoplasms; Penicillin G; Sulbenicillin | 1983 |
[Clinical effect of amikacin. Report of 31 cases].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Child; Ear; Female; Humans; Kanamycin; Kidney; Male; Middle Aged | 1983 |
Empiric antibiotic therapy with an amikacin-carbenicillin-cefoxitin combination in granulocytopenic febrile patients--a clinical report.
Topics: Adult; Aged; Agranulocytosis; Amikacin; Bacterial Infections; Carbenicillin; Cefoxitin; Drug Therapy, Combination; Female; Fever; Humans; Kanamycin; Leukemia; Lymphoma; Male; Middle Aged | 1983 |
Replacement of gentamicin by amikacin as a means of decreasing gentamicin resistance of gram-negative rods in a neonatal intensive care unit.
Topics: Amikacin; Bacterial Infections; Cross Infection; Drug Resistance, Microbial; Gentamicins; Humans; Infant, Newborn; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Kanamycin | 1983 |
Quantitation of amikacin, kanamycin, neomycin, and tobramycin in pharmaceutical dosage forms using the Hantzsch reaction.
Topics: Amikacin; Anti-Bacterial Agents; Capsules; Chemistry, Pharmaceutical; Excipients; Injections; Kanamycin; Neomycin; Solutions; Spectrophotometry; Tablets; Tobramycin | 1983 |
Amikacin concentrations in serum and blister fluid in healthy volunteers and in patients with renal impairment.
Topics: Adolescent; Adult; Amikacin; Blister; Exudates and Transudates; Humans; Kanamycin; Kidney Diseases; Kinetics; Middle Aged; Skin Absorption | 1983 |
[Clinical evaluation of ototoxicity associated with intravenous drip infusion of amikacin].
Topics: Adolescent; Adult; Amikacin; Audiometry, Pure-Tone; Bacterial Infections; Child; Ear; Female; Hearing; Humans; Infusions, Parenteral; Kanamycin; Kidney; Male; Middle Aged; Otorhinolaryngologic Diseases | 1983 |
[Combined action of cephamycin and aminoglycoside antibiotics].
Topics: Amikacin; Aminoglycosides; Animals; Bacteria; Cefoxitin; Dibekacin; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Enterobacteriaceae Infections; Gentamicins; Kanamycin; Male; Mice | 1983 |
Amikacin doses in very low birthweight newborns.
Topics: Amikacin; Humans; Infant, Low Birth Weight; Infant, Newborn; Kanamycin; Kinetics | 1983 |
The accuracy of amikacin administration in neonates.
Topics: Amikacin; Birth Weight; Humans; Infant, Newborn; Infusions, Parenteral; Kanamycin | 1983 |
[Clinical pharmacology of the most frequently used aminoglucosides: gentamycin, tobramycin and amikacin].
Topics: Amikacin; Bacteria; Bacterial Infections; Drug Interactions; Drug Resistance, Microbial; Ear; Gentamicins; Humans; Kanamycin; Kidney; Tobramycin | 1983 |
[Comparative study and time changes in the resistance to gentamycin, tobramycin, sisomicin and amikacin of Gram-negative nosocomial bacterial strains isolated from the urinary tract, in relation to the annual use of the aminoglycosides tested].
Topics: Amikacin; Cross Infection; Drug Resistance, Microbial; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Sisomicin; Tobramycin; Urinary Tract Infections | 1983 |
Amikacin levels in human aqueous humor.
Topics: Aged; Amikacin; Aqueous Humor; Humans; Injections, Intramuscular; Kanamycin; Middle Aged | 1983 |
[Intrathecal administration of amikacin in postoperative refractory meningitis].
Topics: Aged; Amikacin; Humans; Injections, Spinal; Kanamycin; Male; Meningitis; Middle Aged; Postoperative Complications | 1983 |
Clinical application of amikacin dosage based upon lean body mass in patients with different renal function.
Topics: Adolescent; Adult; Aged; Amikacin; Anthropometry; Creatinine; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Kanamycin; Kidney Diseases; Kinetics; Male; Middle Aged | 1984 |
Amikacin concentrations in uninfected postthoracotomy pleural fluid and in serum after intravenous and intrapleural injection.
Topics: Adult; Aged; Amikacin; Exudates and Transudates; Humans; Injections; Injections, Intravenous; Kanamycin; Middle Aged; Pleura; Thoracic Surgery | 1984 |
The association of aminoglycoside plasma levels with mortality in patients with gram-negative bacteremia.
Topics: Adult; Aged; Amikacin; Body Temperature; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Kidney Diseases; Leukocyte Count; Middle Aged; Proteus Infections; Sepsis; Statistics as Topic; Tobramycin | 1984 |
Empiric use of aminoglycosides in hospitals.
Topics: Amikacin; Drug Resistance, Microbial; Drug Utilization; Gentamicins; Hospitals; Humans; Kanamycin | 1984 |
An effect of fosfomycin on the pharmacokinetics of amikacin.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Drug Interactions; Fosfomycin; Intestinal Absorption; Kanamycin; Kidney; Kinetics; Lysosomes; Male; Rats; Rats, Inbred Strains | 1984 |
Liquid chromatographic determination of amikacin in serum with spectrophotometric detection.
Topics: Amikacin; Chromatography, Liquid; Humans; Kanamycin; Radioimmunoassay; Reference Values; Spectrometry, Fluorescence | 1984 |
Stability of aminoglycoside resistance in vitro in gentamicin-resistant Staphylococcus aureus.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteriophage Typing; Drug Resistance, Microbial; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Neomycin; Netilmicin; Species Specificity; Staphylococcus aureus; Streptomycin; Temperature | 1984 |
Transduction of amikacin, gentamicin and tobramycin resistance in Pseudomonas aeruginosa.
Topics: Amikacin; Anti-Bacterial Agents; Drug Resistance, Microbial; F Factor; Gentamicins; Kanamycin; Lysogeny; Pseudomonas aeruginosa; Tobramycin; Transduction, Genetic | 1980 |
Amikacin treatment of Pseudomonas-caused corneal ulcer.
Topics: Adolescent; Adult; Amikacin; Burns; Child; Corneal Ulcer; Drug Resistance, Microbial; Eye Injuries; Humans; Kanamycin; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections | 1980 |
[Susceptibility of Pseudomonas aeruginosa recently isolated from clinical specimens to various antimicrobial agents and changes of susceptibility to carbenicillin, gentamicin and amikacin (author's transl)].
Topics: Amikacin; Carbenicillin; Gentamicins; Kanamycin; Penicillin Resistance; Pseudomonas aeruginosa | 1980 |
Compiled data on aminoglycoside, foremost netilmicin susceptibility of bacterial strains.
Topics: Acinetobacter; Amikacin; Anti-Bacterial Agents; Bacteria; Escherichia coli; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Netilmicin; Pseudomonas aeruginosa; Staphylococcus aureus; Tobramycin | 1980 |
Gentamicin and amikacin disk susceptibility tests with Pseudomonas aeruginosa: definition of minimal inhibitory concentration correlates for susceptible and resistant categories.
Topics: Amikacin; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections | 1981 |
Cefoxitin: synergism with aminoglycosides in vitro.
Topics: Amikacin; Cefoxitin; Dibekacin; Drug Synergism; Escherichia coli; Gentamicins; Kanamycin; Pseudomonas aeruginosa; Staphylococcus aureus; Tobramycin | 1981 |
Comparative in vitro synergistic activity of new beta-lactam antimicrobial agents and amikacin against Pseudomonas aeruginosa and Serratia marcescens.
Topics: Amikacin; Anti-Bacterial Agents; beta-Lactams; Drug Synergism; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Serratia marcescens | 1981 |
Amikacin resistance: transfers in Pseudomonas aeruginosa and Enterobacteriaceae.
Topics: Amikacin; Conjugation, Genetic; Enterobacteriaceae; Kanamycin; Pseudomonas aeruginosa; R Factors | 1981 |
Inhibitory effect of amikacin on Mycobacterium tuberculosis in vitro.
Topics: Amikacin; Antitubercular Agents; Culture Media; Kanamycin; Mycobacterium tuberculosis | 1981 |
The influence of ototoxic drugs on brainstem auditory evoked potentials in man.
Topics: Acoustic Stimulation; Adult; Amikacin; Brain Stem; Cochlear Microphonic Potentials; Evoked Potentials, Auditory; Gentamicins; Hearing Loss, Sensorineural; Humans; Kanamycin; Long-Term Care; Male; Middle Aged; Vancomycin | 1981 |
BB-K 122: in vitro and in vivo activity against ocular pathogens.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Bacterial Infections; Eye Diseases; Female; In Vitro Techniques; Kanamycin; Male; Pneumococcal Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Staphylococcus aureus; Streptococcus | 1981 |
Transduction of amikacin, gentamicin and tobramycin resistance in Pseudomonas aeruginosa with phage F 116 and AP 19, a new wildtype phage.
Topics: Amikacin; Anti-Bacterial Agents; Bacteriophages; Genes, Bacterial; Gentamicins; Kanamycin; Pseudomonas aeruginosa; R Factors; Tobramycin; Transduction, Genetic | 1981 |
[Susceptibility of Pseudomonas aeruginosa to aminoglycosides: effect of free calcium and magnesium].
Topics: Amikacin; Anti-Bacterial Agents; Calcium; Culture Media; Dose-Response Relationship, Drug; Gentamicins; Humans; Kanamycin; Magnesium; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin | 1982 |
Long-term amikacin use. Effects on aminoglycoside susceptibility patterns of gram-negative bacilli.
Topics: Amikacin; Aminoglycosides; Bacterial Infections; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Humans; Kanamycin; Neoplasms; Pseudomonas aeruginosa; Time Factors | 1982 |
[The use of amikacin in the treatment of endometritis caused by Pseudomonas aeruginosa in mares].
Topics: Amikacin; Animals; Endometritis; Female; Horse Diseases; Horses; Kanamycin; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors | 1982 |
[Studies on the antimicrobial activities of gentamicin, amikacin, and tobramycin against Pseudomonas aeruginosa isolated at Hokkaido University Hospital].
Topics: Amikacin; Anti-Bacterial Agents; Drug Resistance, Microbial; Gentamicins; Kanamycin; Pseudomonas aeruginosa; Tobramycin | 1982 |
[Amikacin - resistance in some bacteria isolated in Ankara, and its relation to R plasmids].
Topics: Acinetobacter; Amikacin; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Pseudomonas aeruginosa; R Factors | 1982 |
Activity of amikacin against Mycobacteria in vitro and in murine tuberculosis.
Topics: Amikacin; Animals; Female; Isoniazid; Kanamycin; Mice; Mycobacterium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Streptomycin; Tuberculosis, Pulmonary | 1982 |
In vitro evaluation of N-formimidoyl thienamycin (MK0787) combined with amikacin against gram-negative bacilli and Staphylococcus aureus.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Drug Synergism; Enterobacteriaceae; Gentamicins; Imipenem; Kanamycin; Pseudomonas aeruginosa; Staphylococcus aureus; Thienamycins | 1982 |
The aminoglycosides. Streptomycin, kanamycin, gentamicin, tobramycin, amikacin, netilmicin, sisomicin.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Netilmicin; Sisomicin; Streptomycin; Tobramycin | 1983 |
Biological transformation of kanamycin A to amikacin (BBK-8).
Topics: Amikacin; Bacillus; Biotransformation; Kanamycin | 1983 |
Potentiation of magnesium sulfate--induced neuromuscular weakness by gentamicin, tobramycin, and amikacin.
Topics: Adolescent; Amikacin; Animals; Anti-Bacterial Agents; Drug Synergism; Female; Gentamicins; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intubation, Intratracheal; Kanamycin; Magnesium Sulfate; Male; Mice; Mice, Inbred Strains; Neuromuscular Diseases; Rabbits; Respiratory Insufficiency; Tobramycin | 1983 |
Mycobacterium chelonei keratitis: a case report.
Topics: Aged; Amikacin; Cornea; Corneal Ulcer; Female; Humans; Kanamycin; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous | 1983 |
Influence of type of dialyzer on the pharmacokinetics of amikacin.
Topics: Adolescent; Adult; Amikacin; Female; Half-Life; Humans; Kanamycin; Kidney Failure, Chronic; Kidneys, Artificial; Kinetics; Male; Middle Aged | 1983 |
Aqueous-humor concentrations of amikacin.
Topics: Amikacin; Aqueous Humor; Dose-Response Relationship, Drug; Humans; Kanamycin | 1983 |
Degeneration of cochlear neurons after amikacin intoxication in the rat.
Topics: Amikacin; Animals; Cochlea; Ganglia; Kanamycin; Microscopy, Electron; Neurons, Afferent; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Therapy of experimental Pseudomonas endocarditis with high-dose amikacin and ticarcillin.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Endocarditis, Bacterial; Female; Kanamycin; Microbial Sensitivity Tests; Penicillins; Pseudomonas Infections; Rabbits; Ticarcillin | 1983 |
Influence of age on amikacin pharmacokinetics in patients without renal disease. Comparison with gentamicin and tobramycin.
Topics: Adult; Age Factors; Aged; Amikacin; Anti-Bacterial Agents; Creatinine; Female; Gentamicins; Humans; Kanamycin; Kidney Diseases; Kinetics; Male; Middle Aged; Tobramycin | 1983 |
Monitoring of amikacin in the neonate.
Topics: Age Factors; Amikacin; Gestational Age; Humans; Infant, Newborn; Infant, Small for Gestational Age; Kanamycin; Respiratory Distress Syndrome, Newborn; Time Factors | 1983 |
[The effect of intrathecal amikacin in the treatment of postoperative meningitis (author's transl)].
Topics: Adult; Amikacin; Female; Humans; Infant; Injections, Spinal; Kanamycin; Male; Meningitis; Postoperative Complications | 1980 |
[Experience of amikacin intravenous drip infusion (author's transl)].
Topics: Adult; Aged; Amikacin; Bacterial Infections; Drug Evaluation; Female; Humans; Infusions, Parenteral; Kanamycin; Leukemia, Myeloid, Acute; Male; Middle Aged | 1980 |
[Single daily dose of amikacin in the treatment of urinary tract infections].
Topics: Adolescent; Adult; Aged; Amikacin; Drug Resistance, Microbial; Female; Humans; In Vitro Techniques; Kanamycin; Male; Middle Aged; Urinary Tract Infections | 1980 |
The ototoxic potential of netilmicin compared with amikacin. An animal study in guinea pigs.
Topics: Amikacin; Animals; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Hair Cells, Auditory, Inner; Hearing; Kanamycin; Microscopy, Electron; Netilmicin; Vestibule, Labyrinth | 1980 |
Outbreak of amikacin-resistant Enterobacteriaceae in an intensive care nursery.
Topics: Amikacin; Cross Infection; Disease Outbreaks; Drug Resistance, Microbial; Enterobacter; Enterobacteriaceae Infections; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intensive Care Units; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Male; Netilmicin; Nurseries, Hospital; Serratia marcescens; Sisomicin | 1980 |
Successful treatment of Nocardia asteroides infection with amikacin.
Topics: Adolescent; Amikacin; Female; Humans; Kanamycin; Kidney Transplantation; Nocardia asteroides; Nocardia Infections; Transplantation, Homologous | 1980 |
Loss of an aminoglycoside resistance plasmid by Serratia marcescens during treatment of meningitis with amikacin.
Topics: Amikacin; Aminoglycosides; Drug Combinations; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Male; Meningitis; Plasmids; Serratia marcescens; Tobramycin | 1980 |
Escherichia coli infections in knee joints. The pharmacological and antibacterial effects of intramuscular antibiotics.
Topics: Amikacin; Animals; Arthritis, Infectious; Carbenicillin; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Injections, Intramuscular; Kanamycin; Knee Joint; Microbial Sensitivity Tests; Rabbits; Synovial Fluid | 1980 |
Gentamicin-resistant Serratia marcescens endophthalmitis.
Topics: Amikacin; Anti-Bacterial Agents; Bacteriological Techniques; Drug Resistance, Microbial; Endophthalmitis; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Kanamycin; Middle Aged; Serratia marcescens; Tobramycin | 1980 |
Experimental infection in rabbits evoked by Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli and Klebsiella pneumoniae treated with gentamicin, amikacin and sisomicin.
Topics: Amikacin; Animals; Enterobacteriaceae Infections; Escherichia coli Infections; Gentamicins; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Proteus Infections; Proteus mirabilis; Pseudomonas Infections; Rabbits; Sisomicin | 1980 |
[A case of Klebsiella pneumonia with complication of CO2-narcosis successfully treated with amikacin (author's transl)].
Topics: Aged; Amikacin; Cognition Disorders; Humans; Hypercapnia; Infusions, Parenteral; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Male; Pneumonia | 1980 |
Substrate-labeled fluorescent immunoassay for amikacin in human serum.
Topics: Amikacin; Binding, Competitive; Fluorescent Antibody Technique; Humans; Immune Sera; Kanamycin; Radioimmunoassay; Substrate Specificity | 1980 |
Acquired cross resistance to aminoglycosides in gentamicin-sensitive and gentamicin-resistant strains of enterobacteria.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia coli; Gentamicins; Kanamycin; Proteus mirabilis; Providencia; Tobramycin | 1981 |
Fatal pneumonia. Emergence of an amikacin sulfate-resistant strain of Escherichia coli.
Topics: Amikacin; Drug Resistance, Microbial; Escherichia coli; Humans; Kanamycin; Male; Middle Aged; Pneumonia; Sepsis | 1981 |
Amikacin treatment of Serratia septicemia in critically ill patients.
Topics: Adult; Aged; Amikacin; Anti-Bacterial Agents; Critical Care; Drug Resistance, Microbial; Enterobacteriaceae Infections; Female; Humans; Kanamycin; Male; Middle Aged; Sepsis; Serratia marcescens | 1981 |
Amikacin penetration into synovial fluid during treatment of septic arthritis.
Topics: Aged; Amikacin; Arthritis, Infectious; Enterobacteriaceae Infections; Humans; Kanamycin; Male; Serratia marcescens; Synovial Fluid | 1981 |
Synergistic effect of rabbit specific antiserum and amikacin on the treatment of mice with lethal infection due to Klebsiella pneumoniae.
Topics: Amikacin; Animals; Drug Synergism; Female; Immunization, Passive; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Mice; Rabbits | 1981 |
[Intraventricular amikacin in the treatment of meningoventriculitis caused by Gram-negative organisms].
Topics: Amikacin; Cerebrospinal Fluid; Humans; Infant; Injections, Intraventricular; Kanamycin; Klebsiella Infections; Klebsiella pneumoniae; Male; Meningitis | 1981 |
Aminoglycoside dosing in renal transplant patients. Comparison of nomogram and individualized pharmacokinetic methods in patients with shifting renal function.
Topics: Adolescent; Adult; Amikacin; Aminoglycosides; Bacterial Infections; Enterobacteriaceae Infections; Female; Humans; Kanamycin; Kidney Transplantation; Labyrinth Diseases; Male; Middle Aged; Pseudomonas Infections | 1982 |
Evidence for a chromosomal site specifying amikacin resistance in multiresistant Serratia marcescens.
Topics: Acetyltransferases; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Chromosomes, Bacterial; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Plasmids; Serratia marcescens; Substrate Specificity | 1982 |
Intraventricular cerebrospinal fluid antibiotic concentrations in patients with intraventricular infections.
Topics: Amikacin; Bacterial Infections; Brain Diseases; Cephalothin; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Chloramphenicol; Drainage; Female; Humans; Infant; Infant, Newborn; Injections, Intravenous; Kanamycin; Male; Penicillins | 1982 |
Renal and Auditory toxic effects of amikacin in children with cancer.
Topics: Adolescent; Amikacin; Bacterial Infections; Child; Child, Preschool; Hearing Loss; Hearing Loss, High-Frequency; Humans; Infant; Kanamycin; Kidney Diseases; Neoplasms | 1982 |
[CSF levels of amikacin following systemic application in patients with slightly and severely impaired blood cerebrospinal barrier (author's transl)].
Topics: Adult; Aged; Amikacin; Blood-Brain Barrier; Humans; Kanamycin; Meningitis; Meningitis, Viral; Middle Aged | 1982 |
Change in serum pH in the bioassay of aminoglycoside antibiotics.
Topics: Amikacin; Anti-Bacterial Agents; Biological Assay; Gentamicins; Humans; Hydrogen-Ion Concentration; Kanamycin; Tobramycin | 1982 |
[The combination therapy of amikacin and beta-lactam antibiotic in the severe bacterial infections (author's transl)].
Topics: Adult; Aged; Amikacin; Bacterial Infections; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Kanamycin; Male; Middle Aged; Penicillins | 1982 |
[Clinical report of an aged patient with lung abscess who show an excellent response after long-term administration of amikacin (author's transl)].
Topics: Aged; Amikacin; Bacteria; Drug Resistance, Microbial; Female; Humans; Kanamycin; Lung Abscess; Sepsis | 1982 |
[Clinical studies on amikacin for infectious diseases following intravenous drip infusion (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Amikacin; Child; Cholangitis; Cholecystitis; Drug Evaluation; Female; Humans; Infusions, Parenteral; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Male; Middle Aged; Peritonitis | 1982 |
[Control of serum levels of tobramycin and amikacin during clinical routine treatment conditions (author's transl)].
Topics: Amikacin; Anti-Bacterial Agents; Humans; Kanamycin; Kidney Failure, Chronic; Radioimmunoassay; Tobramycin | 1982 |
Disposition kinetics of amikacin in patients with renal impairment after intramuscular administration.
Topics: Adult; Aged; Amikacin; Creatinine; Humans; Injections, Intramuscular; Kanamycin; Kidney Diseases; Kinetics; Middle Aged | 1982 |
Effects of amikacin sulfate on the motility of stallion and bull spermatozoa at different temperatures and intervals of storage.
Topics: Amikacin; Animals; Cattle; Horses; Kanamycin; Male; Semen Preservation; Sperm Motility; Temperature; Time Factors | 1982 |
Rapid bioluminescent assay of serum amikacin.
Topics: Adenosine Triphosphate; Amikacin; Anti-Bacterial Agents; Humans; Kanamycin; Luciferases; Luminescent Measurements; Time Factors | 1982 |
Determination of amikacin in microlitre quantities of biological fluids by high-performance liquid chromatography using 1-fluoro-2,4-dinitrobenzene derivatization.
Topics: Adult; Amikacin; Animals; Child; Chromatography, High Pressure Liquid; Dinitrofluorobenzene; Guinea Pigs; Half-Life; Humans; Kanamycin; Time Factors | 1982 |
[Ototoxicity and nephrotoxicity of netilmicin and other aminoglycoside antibiotics in rabbits].
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Hair Cells, Auditory; Kanamycin; Kidney Tubules, Proximal; Netilmicin; Rabbits | 1982 |
Amikacin is not removed by XAD-4 hemoperfusion.
Topics: Acute Kidney Injury; Aged; Amikacin; Drug Interactions; Hemoperfusion; Humans; Ion Exchange Resins; Kanamycin; Male; Polystyrenes; Polyvinyls | 1982 |
[Experiences with intravenous drip infusion therapy of amikacin for severe infections in patients of hematological disorder].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Drug Evaluation; Female; Hematologic Diseases; Humans; Infusions, Parenteral; Kanamycin; Male; Middle Aged | 1982 |
[Infections during induction chemotherapy of acute leukemia and their control V. Clinical evaluation of a large dose of amikacin injected intravenously].
Topics: Adolescent; Adult; Aged; Amikacin; Antineoplastic Agents; Bacterial Infections; Drug Evaluation; Female; Humans; Infusions, Parenteral; Kanamycin; Leukemia; Male; Middle Aged | 1982 |
Amikacin in experimental tuberculosis of guinea pigs.
Topics: Amikacin; Animals; Guinea Pigs; Kanamycin; Male; Tuberculosis | 1982 |
Inactivation of amikacin and gentamicin by carbenicillin in patients with end-stage renal failure.
Topics: Amikacin; Carbenicillin; Drug Interactions; Gentamicins; Humans; Kanamycin; Kidney Failure, Chronic; Kinetics; Male | 1982 |
Intraocular penetration of amikacin. Iris binding and bioavailability.
Topics: Administration, Topical; Amikacin; Anterior Chamber; Aqueous Humor; Biological Availability; Cornea; Eye; Humans; Infusions, Parenteral; Injections; Iris; Kanamycin; Radioimmunoassay | 1982 |
Modification in the pharmacokinetics of amikacin during development.
Topics: Aging; Amikacin; Child; Child, Preschool; Half-Life; Humans; Infant; Infant, Newborn; Kanamycin; Kinetics | 1982 |
Electron microscopy study of the effects of amikacin and cefadroxil on colonic anastomoses in rabbits.
Topics: Amikacin; Animals; Cefadroxil; Cephalexin; Colon; Inflammation; Kanamycin; Male; Microscopy, Electron; Postoperative Complications; Rabbits | 1982 |
Influence of intrauterine maturation on the pharmacokinetics of amikacin in the neonatal period.
Topics: Amikacin; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Kanamycin; Kinetics | 1982 |
Evaluation of the renal and auditory function of neonates treated with amikacin.
Topics: Acetylglucosaminidase; Aging; Amikacin; Audiometry, Evoked Response; Behavior; Creatinine; Hearing Disorders; Hearing Tests; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Kidney Diseases; Kidney Function Tests | 1982 |
[Absorption, excretion and distribution of amikacin following intravenous drip infusion. Intravenous drip infusion, one shot intravenous injection and intramuscular administration of amikacin in dogs, rabbits and rats].
Topics: Amikacin; Animals; Dogs; Infusions, Parenteral; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Kinetics; Male; Rabbits; Rats; Rats, Inbred Strains; Tissue Distribution | 1982 |
[Toxicological study of amikacin following intravenous drip infusion. 1. Acute toxicity in rats, rabbits and dogs, and subacute toxicity in rabbits].
Topics: Amikacin; Animals; Blood Chemical Analysis; Body Weight; Dogs; Drinking; Eating; Electrocardiography; Female; Hearing; Hematologic Tests; Infusions, Parenteral; Injections, Intravenous; Kanamycin; Kidney; Lethal Dose 50; Male; Organ Size; Rabbits; Rats; Rats, Inbred Strains | 1982 |
[Toxicological study of amikacin following intravenous drip infusion. 2. Subacute toxicity in dogs after intravenous injection].
Topics: Amikacin; Animals; Blood Chemical Analysis; Body Weight; Dogs; Drinking; Eating; Electrocardiography; Female; Hearing; Hematologic Tests; Injections, Intravenous; Kanamycin; Kidney; Kidney Function Tests; Liver Function Tests; Male; Organ Size | 1982 |
[Effects of intravenous infusion of amikacin. Intraperitoneal administration to rats before and in the early stage of pregnancy. Segment 1].
Topics: Amikacin; Animals; Body Weight; Bone and Bones; Drinking; Eating; Female; Fertility; Fetus; Injections, Intraperitoneal; Kanamycin; Kidney; Male; Pregnancy; Rats | 1982 |
[Experimental and clinical studies of intravenous infusion of amikacin in acute respiratory tract infections].
Topics: Acute Disease; Adult; Aged; Amikacin; Drug Evaluation; Female; Hearing Tests; Humans; Infusions, Parenteral; Kanamycin; Male; Middle Aged; Respiratory Tract Infections | 1982 |
Antimicrobial activity of amikacin combinations against Enterobacteriaceae moderately susceptible to third-generation cephalosporins.
Topics: Amikacin; Cephalosporins; Drug Interactions; Drug Resistance, Microbial; Drug Synergism; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Kanamycin; Microbial Sensitivity Tests | 1982 |
Evaluation of ototoxicity of amino-glycoside antibiotics in rabbits.
Topics: Amikacin; Aminoglycosides; Animals; Dibekacin; Gentamicins; Hair Cells, Auditory; Kanamycin; Kidney; Rabbits | 1982 |
Mechanism of aminoglycoside-induced lysosomal phospholipidosis: in vitro and in vivo studies with gentamicin and amikacin.
Topics: Amikacin; Animals; Female; Gentamicins; Kanamycin; Lysosomes; Phospholipids; Rats; Rats, Inbred Strains; Sphingomyelins | 1982 |
Chemical modification of 3'-deoxyamikacin.
Topics: Amikacin; Bacteria; Chemical Phenomena; Chemistry; Kanamycin | 1982 |
[Studies on the in vitro antibacterial activities of homemade amikacin on the common bacterial pathogens].
Topics: Amikacin; Bacteria; Kanamycin; Microbial Sensitivity Tests | 1982 |
[Clinical use of amikacin sulfate in the treatment of bacterial infections and prevention of postoperative infections in the orthopedic field].
Topics: Adolescent; Adult; Aged; Amikacin; Bacteria; Bacterial Infections; Child; Child, Preschool; Drug Evaluation; Drug Resistance, Microbial; Female; Humans; Kanamycin; Male; Middle Aged; Postoperative Complications; Premedication | 1982 |
[Update on antibiotic therapy. 6) Amikacin].
Topics: Amikacin; Drug Therapy; Gram-Negative Bacteria; Humans; Infusions, Parenteral; Injections, Intramuscular; Kanamycin; Pediatrics; Staphylococcal Infections | 1982 |
The effect of chronologic age on the serum concentrations of amikacin in sick term and premature infants.
Topics: Age Factors; Amikacin; Bacterial Infections; Cross Infection; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Injections, Intravenous; Kanamycin; Microbial Sensitivity Tests | 1981 |
[Evaluation of amikacin intravenous therapy in pediatrics (author's transl)].
Topics: Adolescent; Age Factors; Amikacin; Blood Urea Nitrogen; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Infusions, Parenteral; Injections, Intravenous; Kanamycin; Liver; Male; Urinary Tract Infections; Whooping Cough | 1980 |
[Possible errors in the interpretation of bacterial sensitivity to aminoglycoside antibiotics].
Topics: Amikacin; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Hydrogen-Ion Concentration; Kanamycin; Microbial Sensitivity Tests | 1980 |
Amikacin nephrotoxicity in the rat.
Topics: Amikacin; Animals; Blood Urea Nitrogen; Creatinine; Kanamycin; Kidney Diseases; Male; Rats | 1980 |
Case study: Diagnosis and therapy of bacterial osteomyelitis--role of the medical technologist and clinical pharmacist.
Topics: Aged; Amikacin; Carbenicillin; Drug Therapy, Combination; Humans; Kanamycin; Male; Osteomyelitis; Pseudomonas Infections | 1981 |
[Measurement of serum amikacin. Value in therapy].
Topics: Acute Kidney Injury; Amikacin; Humans; Kanamycin | 1981 |
Comparative nephrotoxicities of dibekacin, amikacin, and gentamicin in a rat model.
Topics: Amikacin; Animals; Dibekacin; Gentamicins; Kanamycin; Kidney; Male; Rats | 1980 |
Resistance to aminoglycoside antibiotics of gram-negative bacilli isolated in Canadian hospitals.
Topics: Amikacin; Anti-Bacterial Agents; Canada; Cross Infection; Drug Resistance, Microbial; Gentamicins; Gram-Negative Aerobic Bacteria; Hospitals, Teaching; Humans; Kanamycin; Tobramycin | 1981 |
Evaluation of a method for enzymic radiochemical assay of tobramycin and amikacin in serum.
Topics: Amikacin; Anti-Bacterial Agents; Bilirubin; Carbon Radioisotopes; Cross Reactions; Evaluation Studies as Topic; Hemoglobins; Humans; Kanamycin; Radioimmunoassay; Reagent Kits, Diagnostic; Tobramycin; Triglycerides | 1981 |
Influence of the route of administration on the pharmacokinetics of amikacin.
Topics: Adolescent; Adult; Aged; Amikacin; Creatinine; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Kinetics; Male; Middle Aged; Models, Biological | 1981 |
[Intravenous administration of amikacin sulfate for the severe infections complicated with hematologic malignancies (author's transl)].
Topics: Amikacin; Bacterial Infections; Drug Evaluation; Female; Gentamicins; Hematologic Diseases; Humans; Infusions, Parenteral; Kanamycin; Middle Aged | 1980 |
[Treatment of bacterial infection in acute leukemia, quadruple chemotherapy using CFX, AMK, TIPC and LCM (author's transl)].
Topics: Acute Disease; Adult; Amikacin; Bacterial Infections; Cefoxitin; Drug Therapy, Combination; Humans; Infusions, Parenteral; Kanamycin; Leukemia; Lincomycin; Middle Aged; Penicillins; Ticarcillin | 1980 |
[Aminoglycoside drip intravenous infusion for severe infections due to leukemia and hematopoietic tumor patients (author's transl)].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Drug Evaluation; Female; Humans; Infusions, Parenteral; Kanamycin; Leukemia; Male; Middle Aged | 1981 |
Amikacin and gentamicin accumulation pharmacokinetics and nephrotoxicity in critically ill patients.
Topics: Amikacin; Critical Care; Gentamicins; Half-Life; Humans; Kanamycin; Kidney; Kinetics; Tissue Distribution | 1981 |
Anti-Pseudomonas activity in bronchial secretions of patients receiving amikacin or tobramycin as a continuous infusion.
Topics: Amikacin; Anti-Bacterial Agents; Bronchi; Humans; Infusions, Parenteral; Kanamycin; Pseudomonas; Tobramycin | 1981 |
Comparative study of the effects of sagamicin, 1 N-HABA-sagamicin, UK-4, Sch 21420, gentamicin and amikacin on the respiration activity of isolated rat kidney mitochondria.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; In Vitro Techniques; Kanamycin; Kidney; Mitochondria; Oxygen Consumption; Rats; Structure-Activity Relationship | 1980 |
Syntheses of 1-N-(2-aminoethoxycarbonyl)kanamycin A and 1-N-(3-aminopropoxycarbonyl)kanamycin A.
Topics: Amikacin; Bacteria; Drug Resistance, Microbial; Kanamycin | 1981 |
[Experience with intravenous drip infusion of amikacin in urological field (author's transl)].
Topics: Adult; Aged; Amikacin; Drug Evaluation; Female; Humans; Infusions, Parenteral; Kanamycin; Male; Middle Aged; Urinary Tract Infections | 1981 |
Treatment and prevention of bacterial infections during cytostatic chemotherapy.
Topics: Agranulocytosis; Amikacin; Bacterial Infections; Blood Transfusion; Carbenicillin; Cephalosporins; Drug Synergism; Granulocytes; Humans; Kanamycin; Neutropenia | 1981 |
[Application of amikacin by intravenous drip infusion (author's transl)].
Topics: Adult; Aged; Amikacin; Bacterial Infections; Female; Humans; Infusions, Parenteral; Kanamycin; Male; Middle Aged | 1981 |
[Laboratory and clinical studies of amikacin intravenous drip infusion for the severe infections complicated with hematologic malignancies (author's transl)].
Topics: Adult; Aged; Amikacin; Bacterial Infections; Drug Evaluation; Female; Hematologic Diseases; Humans; Infusions, Parenteral; Kanamycin; Leukemia; Male; Middle Aged | 1981 |
[Amikacin therapy for serious infections in hematopoietic disorders (author's transl)].
Topics: Adolescent; Adult; Aged; Amikacin; Bacteria; Bacterial Infections; Drug Evaluation; Drug Resistance, Microbial; Female; Hematologic Diseases; Humans; Infusions, Parenteral; Kanamycin; Male; Middle Aged | 1981 |
[Clinical experience of amikacin intravenous drip infusion for digestive organ infection (author's transl)].
Topics: Adolescent; Adult; Amikacin; Bacterial Infections; Child, Preschool; Digestive System Diseases; Drug Evaluation; Female; Humans; Infusions, Parenteral; Kanamycin; Male; Middle Aged; Surgical Wound Infection | 1981 |
[Our experience with amikacin administration in severe burns].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Burns; Child; Child, Preschool; Female; Humans; Kanamycin; Male; Middle Aged | 1980 |
Pharmacokinetics of amikacin in children with normal and impaired renal function.
Topics: Amikacin; Child; Child, Preschool; Female; Humans; Kanamycin; Kidney Diseases; Kinetics; Male | 1981 |
Efficacy of amikacin and ticarcillin as empiric therapy in febrile neutropenic children with cancer.
Topics: Adolescent; Agranulocytosis; Amikacin; Bacterial Infections; Child; Child, Preschool; Evaluation Studies as Topic; Female; Humans; Infant; Kanamycin; Male; Neoplasms; Neutropenia; Penicillins; Ticarcillin | 1981 |
[An evaluation of ototoxicity of aminoglycoside antibiotics in rabbits (author's transl)].
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Hair Cells, Auditory; Kanamycin; Rabbits; Tobramycin | 1981 |
An epidemic oc gentamicin/cloxacillin resistant staphylococcal infection in a neonatal unit.
Topics: Amikacin; Clindamycin; Cloxacillin; Cross Infection; Female; Gentamicins; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Kanamycin; Male; Pneumonia, Staphylococcal; R Factors; Staphylococcal Infections; Staphylococcus aureus | 1981 |
[Clinical experience of amikacin eye lotion (author's transl)].
Topics: Adolescent; Adult; Amikacin; Bacterial Infections; Child; Child, Preschool; Drug Evaluation; Eye Diseases; Female; Humans; Infant; Kanamycin; Male; Middle Aged; Ophthalmic Solutions | 1981 |
[Experience with intravenous drip infusion of amikacin (author's transl)].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Drug Evaluation; Female; Humans; Infusions, Parenteral; Kanamycin; Male; Middle Aged | 1981 |
[A study on the disc sensitivity test for amikacin (author's transl)].
Topics: Amikacin; Bacteria; Culture Media; Drug Resistance, Microbial; Kanamycin; Microbial Sensitivity Tests | 1981 |
Urine concentrations of gentamicin, tobramycin, amikacin, and kanamycin after subcutaneous administration to healthy adult dogs.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Dogs; Female; Gentamicins; Injections, Subcutaneous; Kanamycin; Male; Tobramycin | 1981 |
Intraventricular levels of amikacin after intravenous administration.
Topics: Amikacin; Cerebral Ventricles; Child; Child, Preschool; Half-Life; Humans; Hydrocephalus; Infant; Injections, Intravenous; Kanamycin; Kinetics; Time Factors | 1981 |
Predictive pharmacokinetics of amikacin using actually measured and assumed parameters, applied in 1-compartment linear pharmacokinetics.
Topics: Amikacin; Humans; Infusions, Parenteral; Kanamycin; Kinetics; Models, Biological | 1981 |
[Resistance to amikacin of gentamicin-resistant Staphylococcus aureus].
Topics: Amikacin; Cross Reactions; Drug Resistance, Microbial; Gentamicins; Kanamycin; Phenotype; Staphylococcus aureus | 1980 |
Management of amikacin overdose.
Topics: Adult; Amikacin; Diuresis; Female; Humans; Kanamycin; Peritoneal Dialysis; Sodium Chloride | 1981 |
[Clinical evaluation of amikacin in severe infections with hematological malignant diseases (author's transl)].
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Drug Evaluation; Female; Hematologic Diseases; Humans; Infusions, Parenteral; Kanamycin; Leukemia; Lymphoma; Male; Middle Aged | 1981 |
[The study of washing operative wound with amikacin sulfate solution in the orthopedic surgery].
Topics: Adolescent; Adult; Amikacin; Child; Child, Preschool; Drug Evaluation; Female; Humans; Intraoperative Care; Kanamycin; Male; Middle Aged; Orthopedics; Surgical Wound Infection | 1981 |
Concentrations of kanamycin and amikacin in human gallbladder bile and wall.
Topics: Adolescent; Adult; Aged; Amikacin; Bile; Cholecystectomy; Female; Gallbladder; Humans; Injections, Intramuscular; Kanamycin; Male; Middle Aged | 1981 |
The effect of peritoneal dialysis of the pharmacokinetics of amikacin.
Topics: Aged; Amikacin; Bacterial Infections; Body Weight; Female; Half-Life; Humans; Kanamycin; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Peritoneal Dialysis | 1980 |
Amikacin sulfate levels in human serum and bile.
Topics: Adult; Aged; Amikacin; Bile; Cholecystectomy; Humans; Kanamycin; Male; Middle Aged; Time Factors | 1981 |
[Modern trends in antibiotic therapy of difficult infections: amikacin sulfate. A meeting held in Naples with Professor Fernando De Ritis as Chairman].
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Humans; Kanamycin | 1980 |
Comparative ototoxic effects of RU 25434, amikacin and neomycin in guinea-pigs.
Topics: Age Factors; Amikacin; Aminoglycosides; Animals; Animals, Newborn; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Cochlea; Cochlear Microphonic Potentials; Guinea Pigs; Kanamycin; Neomycin; Reflex | 1980 |
The influence of ascites on the pharmacokinetics of amikacin.
Topics: Amikacin; Ascites; Ascitic Fluid; Female; Humans; Kanamycin; Kinetics; Liver Cirrhosis; Male; Models, Biological | 1980 |
[Bacteriological and clinical results of amikacin].
Topics: Amikacin; Drug Evaluation; Female; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Surgical Wound Infection | 1980 |
Amikacin pharmacokinetics in morbidly obese patients.
Topics: Adult; Amikacin; Body Weight; Female; Humans; Kanamycin; Kinetics; Male; Middle Aged; Models, Biological; Obesity | 1980 |
Lean body mass and amikacin dosage.
Topics: Adolescent; Adult; Aged; Amikacin; Body Weight; Humans; Kanamycin; Middle Aged; Skin Physiological Phenomena | 1980 |
In vitro activity of netilmicin, gentamicin, tobramycin and amikacin against glucose fermenting and nonfermenting bacteria.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Enterobacteriaceae; Fermentation; Gentamicins; Glucose; Kanamycin; Microbial Sensitivity Tests; Netilmicin; Pseudomonas; Staphylococcus; Streptococcus; Tobramycin | 1980 |
Comparative in vitro activity of netilmicin, amikacin, tobramycin and sisomicin against gentamicin highly-resistant enterobacteriaceae.
Topics: Amikacin; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Kanamycin; Netilmicin; Sisomicin; Tobramycin | 1980 |
Evaluation of amikacin dosage regimes in the low and very low birthweight newborn.
Topics: Amikacin; Dose-Response Relationship, Drug; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases; Kanamycin; Male; Sepsis | 1980 |
Effect on the renal function of UK 18892.
Topics: Aged; Amikacin; Bacterial Infections; Female; Glomerular Filtration Rate; Humans; Kanamycin; Kidney; Male; Middle Aged | 1980 |
[Blood level of amikacin after drip intravenous infusion (author's transl)].
Topics: Adult; Aged; Amikacin; Female; Humans; Infusions, Parenteral; Injections, Intramuscular; Kanamycin; Kidney Diseases; Kinetics; Male; Time Factors | 1980 |
Comparative low-dose nephrotoxicities of gentamicin, tobramycin, and amikacin.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gentamicins; Kanamycin; Kidney; Male; Rats; Tobramycin | 1980 |
Prevalence of gentamicin- and amikacin-resistant bacteria in sink drains.
Topics: Amikacin; Bacteria; Bacterial Infections; Cross Infection; Disease Reservoirs; Drainage, Sanitary; Drug Resistance, Microbial; Gentamicins; Humans; Kanamycin; Species Specificity; Water Microbiology | 1980 |
[The distribution of aminoglycoside antibiotics into the lymph and pancreatic fluid in dogs (author's transl)].
Topics: Aged; Amikacin; Animals; Anti-Bacterial Agents; Dibekacin; Dogs; Female; Gentamicins; Humans; Kanamycin; Lymph; Male; Pancreatic Juice; Tobramycin | 1980 |
Synergism involving penicillinase-resistant penicillin.
Topics: Amikacin; Cefazolin; Drug Synergism; Humans; Kanamycin; Methicillin; Microbial Sensitivity Tests; Penicillin Resistance; Staphylococcus aureus | 1980 |
In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents.
Topics: Amikacin; Anti-Bacterial Agents; Erythromycin; Kanamycin; Microbial Sensitivity Tests; Mycobacterium; Tetracyclines | 1980 |
Interpretive standards for disk susceptibility tests with Sch 21420 and amikacin.
Topics: Amikacin; Bacteria; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Regression Analysis | 1980 |
[Amikacin in therapy].
Topics: Amikacin; Bacterial Infections; Humans; Kanamycin | 1980 |
[Unexpected infectious syndromes with severe leukopenia during anticancer chemotherapy. Results of antibiotic treatment "on demand"].
Topics: Amikacin; Amoxicillin; Antineoplastic Agents; Bacterial Infections; Humans; Kanamycin; Leukopenia | 1980 |
Supra-normal sensitivity to ototoxic antibiotic of the developing rat cochlea.
Topics: Age Factors; Amikacin; Animals; Auditory Threshold; Cochlea; Dose-Response Relationship, Drug; Kanamycin; Rats | 1980 |
Phage infection, transfection and transformation of Mycobacterium avium complex and Mycobacterium paratuberculosis.
Topics: AIDS-Related Opportunistic Infections; Amikacin; Animals; Bacteriophages; Humans; Kanamycin; Kinetics; Luciferases; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium subsp. paratuberculosis; Plasmids; Recombinant Proteins; Species Specificity; Transfection; Transformation, Bacterial; Tuberculosis | 1995 |
[Detection of the phenotypes of resistance of enterobacteriaceae to aminoglycosides with ATB Plus Expert System].
Topics: Amikacin; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; In Vitro Techniques; Kanamycin; Kanamycin Resistance; Microbiological Techniques; Netilmicin; Phenotype; Tobramycin | 1993 |
Comparison of the effects of amikacin and kanamycins A and B on dimyristoylphosphatidylglycerol bilayers. An infrared spectroscopic investigation.
Topics: Amikacin; Anti-Bacterial Agents; Kanamycin; Lipid Bilayers; Membrane Fluidity; Phosphatidylglycerols; Spectroscopy, Fourier Transform Infrared | 1997 |
The identification of 1,6'- and 1,3"-di-N-(L-4-amino-2-hydroxybutyryl) derivatives of kanamycin as synthetic byproducts of amikacin.
Topics: Amikacin; Kanamycin; Magnetic Resonance Spectroscopy; Molecular Structure | 1997 |
Characterization of mutants of the 6'-N-acetyltransferase encoded by the multiresistance transposon Tn1331: effect of Phen171-to-Leu171 and Tyr80-to-Cys80 substitutions.
Topics: Acetylation; Acetyltransferases; Amikacin; Amino Acid Substitution; Anti-Bacterial Agents; DNA Transposable Elements; Drug Resistance, Multiple; Kanamycin; Kanamycin Resistance; Klebsiella pneumoniae; Microbial Sensitivity Tests; Mutation; Phenylalanine; Sequence Alignment; Substrate Specificity; Tyrosine | 1998 |
Mechanism of resistance to amikacin and kanamycin in Mycobacterium tuberculosis.
Topics: Amikacin; Antitubercular Agents; Drug Resistance, Multiple; Drug Therapy, Combination; Genes, Bacterial; Humans; Kanamycin; Kanamycin Resistance; Mutation; Mycobacterium tuberculosis | 1998 |
Significant increase in antibiotic resistance of Salmonella isolates from human beings and chicken meat in Thailand.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Animals; Anti-Bacterial Agents; Ceftriaxone; Chickens; Child; Child, Preschool; Drug Resistance, Microbial; Female; Gentamicins; Humans; Infant; Kanamycin; Male; Meat; Middle Aged; Nalidixic Acid; Salmonella; Salmonella Infections; Thailand | 1998 |
[Effect of subinhibitory concentrations of antibiotics on the production of enterohemolysin by enterohemorrhagic Escherichia coli O157:H7].
Topics: Amikacin; Anti-Bacterial Agents; Escherichia coli O157; Escherichia coli Proteins; Gentamicins; Hemolysin Proteins; Kanamycin; Streptomycin | 1999 |
Education vs restriction in rational use of antibiotics.
Topics: Amikacin; Boston; Drug Utilization; Education, Medical, Continuing; Humans; Kanamycin; Pharmacy and Therapeutics Committee; Pharmacy Service, Hospital; Utilization Review | 1978 |
A convenient synthetic pathway for multivalent assembly of aminoglycoside antibiotics starting from amikacin.
Topics: Amikacin; Anti-Bacterial Agents; Binding Sites; Cell Wall; Kanamycin; Ligands; Microbial Sensitivity Tests; Ribosomal Proteins; RNA, Ribosomal; Styrene | 2002 |
Hearing loss and nephrotoxicity in long-term aminoglycoside treatment in patients with tuberculosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Audiometry; Child; Creatinine; Female; Hearing Loss, Bilateral; Humans; Kanamycin; Kidney; Kidney Diseases; Male; Middle Aged; Retrospective Studies; Streptomycin; Time Factors; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2002 |
Inhibition of bacterial IF2 binding to fMet-tRNA((fMet)) by aminoglycosides.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Carbohydrate Sequence; Escherichia coli; Kanamycin; Molecular Sequence Data; Prokaryotic Initiation Factor-2; Protein Denaturation; RNA, Transfer, Met | 2003 |
Discordant resistance to kanamycin and amikacin in drug-resistant Mycobacterium tuberculosis.
Topics: Amikacin; Anti-Bacterial Agents; Antibiotics, Antitubercular; Drug Resistance, Bacterial; Estonia; Genes, Bacterial; Genotype; Kanamycin; Mycobacterium tuberculosis; Polymorphism, Restriction Fragment Length; Tuberculosis | 2003 |
A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Chromatography, Micellar Electrokinetic Capillary; Deoxycholic Acid; Gentamicins; Hydrogen-Ion Concentration; Kanamycin; Netilmicin; Sisomicin; Temperature; Tobramycin | 2003 |
Overexpression and characterization of an aminoglycoside 6'-N-acetyltransferase with broad specificity from an epsilon-poly-L-lysine producer, Streptomyces albulus IFO14147.
Topics: Acetyltransferases; Amikacin; Amino Acid Sequence; Catalysis; Chromatography, Thin Layer; Cloning, Molecular; DNA; Electrophoresis, Polyacrylamide Gel; Enterococcus faecium; Escherichia coli; Hydrolysis; Kanamycin; Kinetics; Models, Chemical; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Paromomycin; Plasmids; Polylysine; Salmonella enteritidis; Sequence Homology, Amino Acid; Streptomyces; Substrate Specificity | 2004 |
Rapid and selective micellar electrokinetic chromatography for simultaneous determination of amikacin, kanamycin A, and tobramycin with UV detection and application in drug formulations.
Topics: Alkanesulfonic Acids; Amikacin; Chromatography, Micellar Electrokinetic Capillary; Hydrogen-Ion Concentration; Kanamycin; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet; Tobramycin; Tromethamine | 2005 |
[A case of pulmonary multiresistant Mycobacterium bovis tuberculosis in Madagascar].
Topics: Amikacin; Antitubercular Agents; Capreomycin; Chronic Disease; Ciprofloxacin; Cough; DNA, Bacterial; Drug Therapy, Combination; Ethionamide; Humans; Kanamycin; Madagascar; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Mycobacterium bovis; Ofloxacin; Patient Compliance; Polymorphism, Restriction Fragment Length; Sputum; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2003 |
Second-line drug susceptibilities of Thai multidrug-resistant Mycobacterium tuberculosis isolates.
Topics: Amikacin; Aminosalicylic Acid; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Ethionamide; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Thailand | 2005 |
Intracellular kinase inhibitors selected from combinatorial libraries of designed ankyrin repeat proteins.
Topics: Amikacin; Aminoglycosides; Ankyrins; Anti-Bacterial Agents; Biotinylation; Catalytic Domain; Chromatography; Cloning, Molecular; Drug Resistance, Bacterial; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Gene Library; Kanamycin; Kanamycin Kinase; Kinetics; Models, Chemical; Models, Molecular; Phenotype; Protein Binding; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Ribosomes; Sensitivity and Specificity; Surface Plasmon Resonance | 2005 |
Mutagenesis analysis of a conserved region involved in acetyl coenzyme A binding in the aminoglycoside 6'-N-acetyltransferase type Ib encoded by plasmid pJHCMW1.
Topics: Acetyl Coenzyme A; Acetyltransferases; Alanine; Amikacin; Amino Acid Sequence; Anti-Bacterial Agents; Conserved Sequence; DNA, Bacterial; Escherichia coli; Kanamycin; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Mutagenesis; Plasmids | 2005 |
Tuning the regioselectivity of the Staudinger reaction for the facile synthesis of kanamycin and neomycin class antibiotics with N-1 modification.
Topics: Amikacin; Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Microbial Sensitivity Tests; Molecular Structure; Neomycin; Stereoisomerism; Structure-Activity Relationship | 2005 |
Molecular analysis of cross-resistance to capreomycin, kanamycin, amikacin, and viomycin in Mycobacterium tuberculosis.
Topics: Amikacin; Antibiotics, Antitubercular; Capreomycin; Drug Resistance, Bacterial; Genes, rRNA; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Protein Biosynthesis; RNA, Ribosomal, 16S; Viomycin | 2005 |
Development and validation of a novel LC non-derivatization method for the determination of amikacin in pharmaceuticals based on evaporative light scattering detection.
Topics: Algorithms; Amikacin; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Indicators and Reagents; Kanamycin; Light; Molecular Weight; Reproducibility of Results; Scattering, Radiation; Sulfates | 2006 |
Influence of gene dosing on antibiotic resistance mediated by inactivating enzymes.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Bleomycin; DNA Transposable Elements; Drug Resistance, Bacterial; Escherichia coli; Gene Dosage; Kanamycin; Streptomycin | 1989 |
Comparative evaluation of the in vitro antimycobacterial activities of six aminoglycoside antibiotics using an agar dilution method.
Topics: Amikacin; Aminoglycosides; Antitubercular Agents; Colony Count, Microbial; Dibekacin; Drug Resistance, Multiple, Bacterial; Gentamicins; Humans; Japan; Kanamycin; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium Infections; Mycobacterium tuberculosis; Nocardia asteroides; Nontuberculous Mycobacteria; Prevalence; Streptomycin; Tobramycin | 2006 |
[Treatment and outcomes of tuberculosis with multidrug resistance of MBT in children and adolescents].
Topics: Adolescent; Amikacin; Antitubercular Agents; Child; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Male; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2007 |
[The role of aminoglycoside--modifying enzymes in resistance of Gram-negative rods].
Topics: Acetyltransferases; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Microbial Sensitivity Tests; Neomycin; Netilmicin; Phenotype; Pseudomonas aeruginosa; Tobramycin | 2006 |
Rapid hair cell loss: a mouse model for cochlear lesions.
Topics: Age Factors; Amikacin; Animals; Anti-Bacterial Agents; Bumetanide; Cell Death; Cell Survival; Cochlear Diseases; Disease Models, Animal; Diuretics; Fluorescent Dyes; Gentamicins; Hair Cells, Auditory, Outer; Kanamycin; Mice; Mice, Inbred CBA; Pyridinium Compounds; Quaternary Ammonium Compounds; Stria Vascularis | 2008 |
Determination of kanamycin A, amikacin and tobramycin residues in milk by capillary zone electrophoresis with post-column derivatization and laser-induced fluorescence detection.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Drug Residues; Electrophoresis, Capillary; Fluorescence; Hydrogen-Ion Concentration; Kanamycin; Linear Models; Milk; Sensitivity and Specificity; Tobramycin | 2009 |
Characterization of conjugative plasmids carrying antibiotic resistance genes encoding 16S rRNA methylase, extended-spectrum beta-lactamase, and/or plasmid-mediated AmpC beta-lactamase.
Topics: Amikacin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli Proteins; Gene Transfer, Horizontal; Gentamicins; Humans; Kanamycin; Methyltransferases; Microbial Sensitivity Tests; Plasmids; Polymorphism, Restriction Fragment Length; Tobramycin | 2009 |
Cross-resistance of Mycobacterium tuberculosis isolates among streptomycin, kanamycin and amikacin.
Topics: Amikacin; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Humans; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Streptomycin; Tuberculosis, Multidrug-Resistant | 2009 |
In vitro interference of Hyptis martiusii Benth. & chlorpromazine against an aminoglycoside-resistant Escherichia coli.
Topics: Amikacin; Anti-Bacterial Agents; Chlorpromazine; Drug Synergism; Escherichia coli; Hyptis; In Vitro Techniques; Indicator Dilution Techniques; Kanamycin; Microbial Sensitivity Tests; Plant Extracts; Tobramycin | 2009 |
High level of cross-resistance between kanamycin, amikacin, and capreomycin among Mycobacterium tuberculosis isolates from Georgia and a close relation with mutations in the rrs gene.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Georgia (Republic); Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant | 2009 |
Comparison of different aminoglycoside antibiotic treatments to refine ototoxicity studies in adult mice.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Cochlea; Disease Models, Animal; Dose-Response Relationship, Drug; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Hearing Loss; Kanamycin; Male; Mice; Mice, Inbred C57BL; Mortality; Neomycin | 2010 |
Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis.
Topics: Acetyltransferases; Amikacin; Anti-Bacterial Agents; Antigens, Bacterial; Antitubercular Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Humans; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Promoter Regions, Genetic; Transcription, Genetic; Tuberculosis, Multidrug-Resistant | 2009 |
Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Cations; Framycetin; Kanamycin; Male; Mice; Polymers; Structure-Activity Relationship; Surface-Active Agents | 2010 |
[Occurrence of 16s rRNA methylase ArmA producing Enterobacteriaceae in a general hospital in Warsaw, Poland].
Topics: Amikacin; Drug Resistance, Microbial; Enterobacteriaceae; Environmental Microbiology; Environmental Monitoring; Gentamicins; Hospitals, General; Kanamycin; Methyltransferases; Microbial Sensitivity Tests; Poland | 2010 |
Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Ciprofloxacin; Ethambutol; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin | 2011 |
Comparison of clinical isolates and in vitro selected mutants reveals that tlyA is not a sensitive genetic marker for capreomycin resistance in Mycobacterium tuberculosis.
Topics: Acetyltransferases; Amikacin; Antigens, Bacterial; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA, Bacterial; Drug Resistance, Bacterial; Genetic Markers; Humans; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Point Mutation; Promoter Regions, Genetic; RNA, Ribosomal, 16S; Sensitivity and Specificity; Sequence Analysis, DNA | 2011 |
Linezolid safety, tolerability and efficacy to treat multidrug- and extensively drug-resistant tuberculosis.
Topics: Acetamides; Adult; Amikacin; Antitubercular Agents; Capreomycin; Drug-Related Side Effects and Adverse Reactions; Extensively Drug-Resistant Tuberculosis; Female; Fluoroquinolones; Humans; Infectious Disease Medicine; Isoniazid; Kanamycin; Linezolid; Male; Middle Aged; Oxazolidinones; Rifampin | 2011 |
Streptomycin interference in Jaffe reaction - possible false positive creatinine estimation in excessive dose exposure.
Topics: Amikacin; Anti-Bacterial Agents; Chemistry, Clinical; Creatinine; Dose-Response Relationship, Drug; False Positive Reactions; Gentamicins; Humans; Kanamycin; Netilmicin; Picrates; Streptomycin; Tobramycin | 2013 |
Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea.
Topics: Acetyltransferases; Amidohydrolases; Amikacin; Antigens, Bacterial; Bacterial Proteins; Capreomycin; Catalase; DNA Gyrase; DNA Primers; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Ethambutol; Fluoroquinolones; Genetic Loci; Humans; Isoniazid; Kanamycin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Oxidoreductases; Pentosyltransferases; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyrazinamide; Republic of Korea; Rifampin; Sequence Analysis, DNA; Streptomycin; Tuberculosis, Multidrug-Resistant | 2013 |
Prevalence and genetic characterization of second-line drug-resistant and extensively drug-resistant Mycobacterium tuberculosis in Rural China.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Antitubercular Agents; Capreomycin; China; Cross-Sectional Studies; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Fluoroquinolones; Genes, Bacterial; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Mycobacterium tuberculosis; Prevalence; Rural Population; Young Adult | 2013 |
Mycobacterium tuberculosis rrs A1401G mutation correlates with high-level resistance to kanamycin, amikacin, and capreomycin in clinical isolates from mainland China.
Topics: Amikacin; Antitubercular Agents; Capreomycin; China; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; RNA, Ribosomal, 16S; Tuberculosis | 2013 |
Proteomic analysis of Mycobacterium tuberculosis isolates resistant to kanamycin and amikacin.
Topics: Amikacin; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Iron; Kanamycin; Molecular Docking Simulation; Mycobacterium tuberculosis; Proteome; Proteomics | 2013 |
Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis.
Topics: Acetylation; Acetyltransferases; Amikacin; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Catalytic Domain; Coenzyme A; Crystallography, X-Ray; Drug Resistance, Bacterial; Kanamycin; Molecular Dynamics Simulation; Mycobacterium tuberculosis; Protein Binding; Stereoisomerism; Tobramycin | 2013 |
First proficiency testing of second-line anti-tuberculosis drug susceptibility testing in 12 provinces of China.
Topics: Amikacin; Antitubercular Agents; Capreomycin; China; Drug Resistance, Bacterial; Humans; Kanamycin; Laboratory Proficiency Testing; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Observer Variation; Ofloxacin; Predictive Value of Tests; Quality Control; Quality Indicators, Health Care; Reproducibility of Results; Tuberculosis | 2013 |
Plasma drug activity in patients on treatment for multidrug-resistant tuberculosis.
Topics: Adolescent; Adult; Amikacin; Antitubercular Agents; Cycloserine; Ethionamide; Female; Fluoroquinolones; Humans; Kanamycin; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Sputum; Tanzania; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2014 |
Second-line drug susceptibility breakpoints for Mycobacterium tuberculosis using the MODS assay.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; India; Kanamycin; Microbial Sensitivity Tests; Microscopy; Moldova; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Peru; Predictive Value of Tests; Reproducibility of Results; South Africa; Sputum; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2014 |
Molecular and phenotypic characterization of multidrug-resistant Mycobacterium tuberculosis isolates resistant to kanamycin, amikacin, and capreomycin in China.
Topics: Amikacin; Antitubercular Agents; Capreomycin; China; Drug Resistance, Multiple, Bacterial; Genotype; Humans; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Point Mutation; Tuberculosis, Multidrug-Resistant | 2014 |
Molecular characterization of amikacin, kanamycin and capreomycin resistance in M/XDR-TB strains isolated in Thailand.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Humans; Kanamycin; Mycobacterium tuberculosis; Point Mutation; Sputum; Thailand | 2014 |
Sensitization of intracellular Salmonella enterica serovar Typhimurium to aminoglycosides in vitro and in vivo by a host-targeted antimicrobial agent.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Gentamicins; Injections, Intraperitoneal; Kanamycin; Macrophages; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Microbial Viability; Pyrazoles; Salmonella Infections, Animal; Salmonella typhimurium; Streptomycin; Sulfonamides; Survival Analysis | 2014 |
Quantification of amikacin and kanamycin in serum using a simple and validated LC-MS/MS method.
Topics: Adult; Aged; Amikacin; Anti-Bacterial Agents; Chromatography, Liquid; Drug Monitoring; Female; Humans; Kanamycin; Male; Middle Aged; Tandem Mass Spectrometry; Young Adult | 2014 |
Disparities in capreomycin resistance levels associated with the rrs A1401G mutation in clinical isolates of Mycobacterium tuberculosis.
Topics: Amikacin; Antibiotics, Antitubercular; Capreomycin; Drug Resistance, Multiple, Bacterial; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant | 2015 |
Frequency distribution of genes encoding aminoglycoside modifying enzymes in uropathogenic E. coli isolated from Iranian hospital.
Topics: Amikacin; Anti-Bacterial Agents; Disk Diffusion Antimicrobial Tests; Drug Resistance, Bacterial; Escherichia coli Infections; Gene Expression Regulation, Bacterial; Gene Frequency; Genes, Bacterial; Gentamicins; Hospitals, Teaching; Humans; Iran; Kanamycin; Netilmicin; Tobramycin; Urinary Tract Infections; Uropathogenic Escherichia coli | 2014 |
Transport across the outer membrane porin of mycolic acid containing actinomycetales: Nocardia farcinica.
Topics: Amikacin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Biological Transport; Cell Membrane; Cell Wall; Ertapenem; Escherichia coli; Gene Expression; Hydrophobic and Hydrophilic Interactions; Kanamycin; Liposomes; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Mycolic Acids; Nocardia; Porins; Recombinant Proteins; Static Electricity; Structural Homology, Protein | 2015 |
Limited sampling strategies for therapeutic drug monitoring of amikacin and kanamycin in patients with multidrug-resistant tuberculosis.
Topics: Adult; Amikacin; Antitubercular Agents; Biostatistics; Drug Monitoring; Female; Humans; Kanamycin; Male; Models, Statistical; Retrospective Studies; Specimen Handling; Tuberculosis, Multidrug-Resistant; Young Adult | 2015 |
Comparative Proteomic Analysis of Aminoglycosides Resistant and Susceptible Mycobacterium tuberculosis Clinical Isolates for Exploring Potential Drug Targets.
Topics: Amikacin; Amino Acid Motifs; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Cell Membrane; Conserved Sequence; Drug Delivery Systems; Drug Resistance, Microbial; Electrophoresis, Gel, Two-Dimensional; Humans; Iron; Kanamycin; Kanamycin Resistance; Membrane Proteins; Models, Molecular; Molecular Docking Simulation; Mycobacterium tuberculosis; Protein Conformation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteomics; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Tuberculosis; Ubiquitins | 2015 |
Comparing amikacin and kanamycin-induced hearing loss in multidrug-resistant tuberculosis treatment under programmatic conditions in a Namibian retrospective cohort.
Topics: Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Body Weight; Chi-Square Distribution; Child; Child, Preschool; Coinfection; Hearing Loss; Hearing Tests; HIV Infections; Humans; Incidence; Infant; Infant, Newborn; Kanamycin; Logistic Models; Middle Aged; Namibia; Retrospective Studies; Risk Assessment; Risk Factors; Sex Factors; Tuberculosis, Multidrug-Resistant | 2015 |
Frequency of Aminoglycoside-Modifying Enzymes and ArmA Among Different Sequence Groups of Acinetobacter baumannii in Iran.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Clone Cells; Drug Resistance, Bacterial; Gene Expression; Gene Frequency; Genotype; Gentamicins; Hospitals; Humans; Iran; Kanamycin; Methyltransferases; Microbial Sensitivity Tests; Multilocus Sequence Typing; Netilmicin; Phenotype; Phylogeny; Tobramycin | 2016 |
Drug-resistant tuberculosis plagues India.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; India; Isoniazid; Kanamycin; Medication Adherence; Mycobacterium tuberculosis; Nonprescription Drugs; Rifampin; Tuberculosis, Multidrug-Resistant | 2016 |
Correlating rrs and eis promoter mutations in clinical isolates of Mycobacterium tuberculosis with phenotypic susceptibility levels to the second-line injectables.
Topics: Acetyltransferases; Amikacin; Anti-Bacterial Agents; Antigens, Bacterial; Bacterial Proteins; Capreomycin; Drug Resistance, Multiple, Bacterial; Genes, rRNA; Genotype; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Phenotype; Promoter Regions, Genetic; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant | 2016 |
Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates.
Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Tuberculosis | 2016 |
Performance of the New Version (v2.0) of the GenoType MTBDRsl Test for Detection of Resistance to Second-Line Drugs in Multidrug-Resistant Mycobacterium tuberculosis Complex Strains.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Bacterial; Fluoroquinolones; Genes, Bacterial; Genotyping Techniques; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Sensitivity and Specificity; Tuberculosis, Multidrug-Resistant | 2016 |
Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China.
Topics: Amikacin; China; Extensively Drug-Resistant Tuberculosis; Humans; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sensitivity and Specificity; Sputum; Tuberculosis, Multidrug-Resistant | 2016 |
M. tuberculosis ferritin (Rv3841): Potential involvement in Amikacin (AK) & Kanamycin (KM) resistance.
Topics: Amikacin; Cloning, Molecular; Drug Resistance, Microbial; Ferritins; Genes, Bacterial; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmids; Protein Interaction Mapping; Recombinant Proteins; Restriction Mapping; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transformation, Genetic | 2016 |
Micellar Electrokinetic Chromatography of Aminoglycosides.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Cyclodextrins; Chromatography, Micellar Electrokinetic Capillary; Kanamycin; Micelles; Netilmicin; Sisomicin; Tobramycin | 2016 |
eis Promoter C14G and C15G Mutations Do Not Confer Kanamycin Resistance in Mycobacterium tuberculosis.
Topics: Acetyltransferases; Amikacin; Antigens, Bacterial; Antitubercular Agents; Bacterial Proteins; Gene Expression; Genotype; Kanamycin; Kanamycin Resistance; Mutation; Mycobacterium tuberculosis; Promoter Regions, Genetic; Transduction, Genetic | 2016 |
Detection of Isoniazid-, Fluoroquinolone-, Amikacin-, and Kanamycin-Resistant Tuberculosis in an Automated, Multiplexed 10-Color Assay Suitable for Point-of-Care Use.
Topics: Alleles; Amikacin; Antitubercular Agents; Automation, Laboratory; DNA, Bacterial; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Genes, Bacterial; Humans; Isoniazid; Kanamycin; Molecular Diagnostic Techniques; Mycobacterium tuberculosis; Point-of-Care Systems; Polymerase Chain Reaction; Sensitivity and Specificity | 2017 |
Comprehensive study to investigate the role of various aminoglycoside resistance mechanisms in clinical isolates of Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amikacin; Aminoglycosides; Chi-Square Distribution; Drug Resistance, Bacterial; Gentamicins; Humans; Iran; Kanamycin; Netilmicin; Polymerase Chain Reaction; RNA, Ribosomal, 16S; Tobramycin; tRNA Methyltransferases | 2017 |
Molecular Investigation of Resistance to Second-Line Injectable Drugs in Multidrug-Resistant Clinical Isolates of Mycobacterium tuberculosis in France.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Drug Resistance, Multiple, Bacterial; France; Humans; Kanamycin; Mutation; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant | 2017 |
New aminoglycoside-modifying enzymes APH(3')-VIII and APH(3')-IX in Acinetobacter rudis and Acinetobacter gerneri.
Topics: Acinetobacter; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Kanamycin; Kanamycin Kinase; Microbial Sensitivity Tests | 2017 |
RNA expression analysis of efflux pump genes in clinical isolates of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis in South Korea.
Topics: Adenosine Triphosphatases; Amikacin; Antitubercular Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Capreomycin; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Gene Expression; Genes, Bacterial; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Sequence Analysis, DNA; Tuberculosis, Pulmonary | 2017 |
Reduced Chance of Hearing Loss Associated with Therapeutic Drug Monitoring of Aminoglycosides in the Treatment of Multidrug-Resistant Tuberculosis.
Topics: Adult; Amikacin; Antitubercular Agents; Area Under Curve; Audiometry; Biological Availability; Drug Administration Schedule; Drug Dosage Calculations; Drug Monitoring; Extensively Drug-Resistant Tuberculosis; Female; Hearing Loss; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Retrospective Studies | 2017 |
Dissemination of Genes Encoding Aminoglycoside-Modifying Enzymes and armA Among Enterobacteriaceae Isolates in Northwest Iran.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Gentamicins; Hospitals; Humans; Iran; Kanamycin; Methyltransferases; Microbial Sensitivity Tests; Sequence Analysis, DNA; Streptomycin; Tobramycin | 2017 |
First Insight Into the Fluoroquinolone and Aminoglycoside Resistance of Multidrug-Resistant
Topics: Adult; Aged; Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Fluoroquinolones; Genes, Bacterial; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Molecular Typing; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Retrospective Studies; Risk Factors; Saudi Arabia; Tandem Repeat Sequences; Tuberculosis, Pulmonary | 2017 |
Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Bile Acids and Salts; Biofilms; Chick Embryo; Humans; Kanamycin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Vancomycin | 2017 |
Extensively drug-resistant tuberculosis (XDR-TB) in Morocco.
Topics: Adolescent; Adult; Aged; Amikacin; Extensively Drug-Resistant Tuberculosis; Female; Genotype; Humans; Kanamycin; Male; Microbial Sensitivity Tests; Middle Aged; Morocco; Mutation; Mycobacterium tuberculosis; Ofloxacin; Young Adult | 2017 |
Molecular characterization of mutations associated with resistance to second-line tuberculosis drug among multidrug-resistant tuberculosis patients from high prevalence tuberculosis city in Morocco.
Topics: Amikacin; Antitubercular Agents; Base Sequence; Capreomycin; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Gene Frequency; Humans; Kanamycin; Microbial Sensitivity Tests; Morocco; Mutation; Mycobacterium tuberculosis; Ofloxacin; Prevalence; Tuberculosis, Multidrug-Resistant | 2018 |
Determining Genotypic Drug Resistance by Ion Semiconductor Sequencing With the Ion AmpliSeq™ TB Panel in Multidrug-Resistant Mycobacterium tuberculosis Isolates.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Genotype; Humans; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenotype; Polymerase Chain Reaction; Semiconductors; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant | 2018 |
Overexpression of eis without a mutation in promoter region of amikacin- and kanamycin-resistant Mycobacterium tuberculosis clinical strain.
Topics: Acetyltransferases; Amikacin; Antitubercular Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Gene Expression; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Promoter Regions, Genetic; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant | 2018 |
Role of M.tuberculosis protein Rv2005c in the aminoglycosides resistance.
Topics: Amikacin; Aminoglycosides; Antigens, Bacterial; Antitubercular Agents; Bacterial Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Gene Expression Regulation, Bacterial; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Protein Interaction Maps; Tuberculosis, Multidrug-Resistant | 2019 |
Nephrotoxicity and ototoxic symptoms of injectable second-line anti-tubercular drugs among patients treated for MDR-TB in Ethiopia: a retrospective cohort study.
Topics: Adolescent; Adult; Aged; Amikacin; Antitubercular Agents; Capreomycin; Child; Child, Preschool; Creatinine; Ethiopia; Female; HIV Infections; Humans; Kanamycin; Kidney Diseases; Male; Middle Aged; Ototoxicity; Retrospective Studies; Tuberculosis, Multidrug-Resistant; Young Adult | 2019 |
Frequency and patterns of second-line resistance conferring mutations among MDR-TB isolates resistant to a second-line drug from eSwatini, Somalia and Uganda (2014-2016).
Topics: Amikacin; Antitubercular Agents; Capreomycin; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Eswatini; Fluoroquinolones; Gene Frequency; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Sequence Analysis, DNA; Somalia; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Uganda | 2019 |
Prevalence and molecular characterization of amikacin resistance among Mycobacterium tuberculosis clinical isolates from southern China.
Topics: Amikacin; Capreomycin; China; Drug Resistance, Multiple, Bacterial; Humans; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prevalence | 2020 |
Prevalence of Pre-Existing Hearing Loss Among Patients With Drug-Resistant Tuberculosis in South Africa.
Topics: Adolescent; Adult; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Antitubercular Agents; Audiometry; Auditory Threshold; Cross-Sectional Studies; Female; Hearing Loss; HIV Infections; Humans; Hypoalbuminemia; Kanamycin; Male; Middle Aged; Ototoxicity; Prevalence; Renal Insufficiency; South Africa; Thinness; Tuberculosis, Multidrug-Resistant; Young Adult | 2020 |
Sequence-based detection of first-line and second-line drugs resistance-associated mutations in Mycobacterium tuberculosis isolates in Isfahan, Iran.
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Antitubercular Agents; Capreomycin; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Genetic Variation; Genotype; Humans; Iran; Isoniazid; Kanamycin; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant | 2020 |
Role of Epistasis in Amikacin, Kanamycin, Bedaquiline, and Clofazimine Resistance in Mycobacterium tuberculosis Complex.
Topics: Amikacin; Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Epistasis, Genetic; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant | 2021 |
Detection of isoniazid, fluoroquinolone, ethionamide, amikacin, kanamycin, and capreomycin resistance by the Xpert MTB/XDR assay: a cross-sectional multicentre diagnostic accuracy study.
Topics: Adult; Amikacin; Australia; Capreomycin; Cross-Sectional Studies; Drug Resistance, Bacterial; Ethionamide; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prospective Studies; Rifampin; Sensitivity and Specificity; Sputum; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2022 |
Use of Whole-Genome Sequencing to Predict
Topics: Amikacin; Aminosalicylic Acid; Antitubercular Agents; China; Cycloserine; Drug Resistance; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Rifampin; Streptomycin; Tuberculosis, Multidrug-Resistant | 2022 |
Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS.
Topics: Amikacin; Antitubercular Agents; China; Drug Resistance; Ethambutol; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nucleotides; Ofloxacin; Rifampin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomycin; Tuberculosis, Lymph Node | 2022 |
Distribution of Common and Rare Genetic Markers of Second-Line-Injectable-Drug Resistance in Mycobacterium tuberculosis Revealed by a Genome-Wide Association Study.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple, Bacterial; Genetic Markers; Genome-Wide Association Study; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis | 2022 |
Novel amikacin resistance genes identified from human gut microbiota by functional metagenomics.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gastrointestinal Microbiome; Humans; Kanamycin; Methyltransferases; Microbial Sensitivity Tests; RNA, Ribosomal, 16S | 2022 |
Molecular Characterization of Resistance to Second-Line Anti-Mycobacterial Drugs among Clinical Isolates of Multidrug-Resistant Mycobacterium tuberculosis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Humans; Iran; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant | 2023 |
Clinical Evaluation of the XDR-LFC Assay for the Molecular Detection of Isoniazid, Rifampin, Fluoroquinolone, Kanamycin, Capreomycin, and Amikacin Drug Resistance in a Prospective Cohort.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prospective Studies; Rifampin; Tuberculosis, Multidrug-Resistant | 2023 |
Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome.
Topics: Amikacin; Anti-Bacterial Agents; Kanamycin; Models, Molecular; Ribosomes; RNA, Transfer | 2023 |
Genotypic and phenotypic comparison of drug resistance profiles of clinical multidrug-resistant Mycobacterium tuberculosis isolates using whole genome sequencing in Latvia.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Humans; Isoniazid; Kanamycin; Latvia; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant; Whole Genome Sequencing | 2023 |
Synergistic effect of kanamycin and amikacin with setomimycin on biofilm formation inhibition of Listeria monocytogenes.
Topics: Amikacin; Anti-Bacterial Agents; Biofilms; Hemolysin Proteins; Humans; Kanamycin; Listeria monocytogenes; Listeriosis | 2023 |