amifostine anhydrous and fluorouracil

amifostine anhydrous has been researched along with fluorouracil in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's7 (28.00)18.2507
2000's14 (56.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gyergyay, F; Peters, GJ; Pinedo, HM; Treskes, M; van der Vijgh, WJ; van der Wilt, CL; van Laar, JA1
Gyergyay, F; Peters, GJ; Smid, K; van der Wilt, CL; van Laar, JA1
Peters, GJ; Treskes, M; van der Vijgh, WJ; van der Wilt, CL; van Laar, JA1
Rivoire, M1
Byfield, JE1
Bearman, SI; Jones, RB; Myers, S; Purdy, M; Shpall, EJ; Stemmer, SM1
Fahlke, J; Lippert, H; Ridwelski, K1
Altmann, S; Hoffmanns, H1
Fuhlroth, J; Martens-Lobenhoffer, J; Ridwelski, K1
Dunst, J; Müller, AC; Pigorsch, S; Reese, T; Semlin, S1
Genvresse, I; Harder, H; Lange, C; Possinger, K; Schanz, J; Schweigert, M; Späth-Schwalbe, E1
Frangiadaki, C; Georgoulias, V; Giatromanolaki, A; Kakolyris, S; Koukourakis, MI; Kouroussis, C; Retalis, G; Sivridis, E1
Myerson, R1
Birnbaum, E; Dietz, D; Fleshman, J; Kodner, I; Myerson, R; Picus, J; Ratkin, G; Zobeiri, I1
Claussen, U; Dreidax, M; Dunst, J; Kuechler, A; Liehr, T; Pigorsch, SU; Wendt, TG1
Kosmas, C; Koufos, C; Margaris, H; Papalambros, E; Papantoniou, N; Retalis, G; Rokana, S; Tsavaris, N; Vadiaka, M; Zografos, G; Zonios, D1
Chalian, AA; Hershock, D; Lustig, R; Machtay, M; Miller, L; Rosenthal, DI; Weber, RS; Weinstein, GS1
Mazeron, JJ1
Abdel-Wahab, M; Abitbol, A; Hamilton-Nelson, K; Harvey, M; Lewin, A; Markoe, A; Troner, M; Wu, J1
Kaji, H; Maiguma, T; Makino, K; Teshima, D1
Chloropoulou, PA; Giatromanolaki, A; Kouklakis, G; Koukourakis, MI; Lyratzopoulos, N; Manolas, K; Pitiakoudis, M; Sivridis, E; Tsoutsou, P1
Alencar, NMN; Barbosa, CRN; Barbosa, SCM; Brito, GAC; Callado, RB; Carvalho, LL; Lima-Júnior, RCP; Lopes, CDH; Lucetti, LT; Pereira, VBM; Santana, APM; Silva, CAA; Wong, DVT1

Reviews

1 review(s) available for amifostine anhydrous and fluorouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

8 trial(s) available for amifostine anhydrous and fluorouracil

ArticleYear
New strategies in marrow purging for breast cancer patients receiving high-dose chemotherapy with autologous bone marrow transplantation.
    Breast cancer research and treatment, 1993, Volume: 26 Suppl

    Topics: Amifostine; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Stem Cells

1993
High-dose therapy with combined 5-fluorouracil and folinic acid with and without amifostine in the treatment of patients with metastatic colorectal carcinoma.
    International journal of colorectal disease, 1999, Volume: 14, Issue:2

    Topics: Amifostine; Antidotes; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Mucous Membrane; Prospective Studies; Radiation-Protective Agents

1999
[Cytoprotection with amifostine in radiotherapy or radio-chemotherapy of head and neck tumors].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1999, Volume: 175 Suppl 4

    Topics: Adult; Aged; Amifostine; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Cytoprotection; Fluorouracil; Head and Neck Neoplasms; Humans; Middle Aged; Mouth Mucosa; Postoperative Care; Preoperative Care; Radiation-Protective Agents; Radiotherapy; Radiotherapy Dosage; Retrospective Studies; Stomatitis; Time Factors

1999
Intermittent use of amifostine during postoperative radiochemotherapy and acute toxicity in rectal cancer patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2000, Volume: 176, Issue:9

    Topics: Amifostine; Chemotherapy, Adjuvant; Combined Modality Therapy; Dose Fractionation, Radiation; Fluorouracil; Humans; Neoplasm Staging; Radiation Injuries; Radiation-Protective Agents; Radiotherapy, Adjuvant; Rectal Neoplasms

2000
Early results from a phase I/II radiation dose-escalation study with concurrent amifostine and infusional 5-fluorouracil chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma.
    Seminars in oncology, 2002, Volume: 29, Issue:6 Suppl 19

    Topics: Adenocarcinoma; Amifostine; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytoprotection; Fluorouracil; Humans; Neoplasm Recurrence, Local; Radiation Injuries; Radiation-Protective Agents; Radiotherapy Dosage; Rectal Neoplasms

2002
Residual chromosomal damage after radiochemotherapy with and without amifostine detected by 24-color FISH.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2003, Volume: 179, Issue:7

    Topics: Aged; Amifostine; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Chromosome Aberrations; Chromosome Painting; Combined Modality Therapy; DNA Damage; Dose-Response Relationship, Drug; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Lymphocytes; Male; Middle Aged; Radiation-Protective Agents; Radiotherapy, Adjuvant; Rectal Neoplasms

2003
Phase II study of tolerance and efficacy of hyperfractionated radiation therapy and 5-fluorouracil, cisplatin, and paclitaxel (taxol) and amifostine (ethyol) in head and neck squamous cell carcinomas: A-3 protocol.
    American journal of clinical oncology, 2005, Volume: 28, Issue:5

    Topics: Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Paclitaxel

2005
Bevacizumab, capecitabine, amifostine, and preoperative hypofractionated accelerated radiotherapy (HypoArc) for rectal cancer: a Phase II study.
    International journal of radiation oncology, biology, physics, 2011, Jun-01, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amifostine; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dose Fractionation, Radiation; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Radiography; Rectal Neoplasms; Young Adult

2011

Other Studies

16 other study(ies) available for amifostine anhydrous and fluorouracil

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Protection by WR-2721 of the toxicity induced by the combination of cisplatin and 5-fluorouracil.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:4

    Topics: Amifostine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Tumor Cells, Cultured

1992
Biochemical modification of the toxicity and the anti-tumour effect of 5-fluorouracil and cis-platinum by WR-2721 in mice.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:12

    Topics: Amifostine; Animals; Cisplatin; Colonic Neoplasms; Female; Fluorouracil; Leukopenia; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Thrombocytopenia; Thymidylate Synthase; Time Factors; Weight Loss

1992
Effect of WR-2721 on the toxicity and antitumor activity of the combination of carboplatin and 5-fluorouracil.
    Cancer chemotherapy and pharmacology, 1992, Volume: 31, Issue:2

    Topics: Amifostine; Anemia; Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Colonic Neoplasms; Female; Fluorouracil; Leukopenia; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Random Allocation; Thrombocytopenia; Weight Loss

1992
[Cancers of the colon and the rectum: news in 1992].
    Pathologie-biologie, 1992, Volume: 40, Issue:9 Pt 2

    Topics: Amifostine; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Leucovorin; Levamisole; Rectal Neoplasms

1992
Combined use of drugs and radiation in the treatment of liver metastases.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1986, Volume: 100

    Topics: Amifostine; Bromodeoxyuridine; Combined Modality Therapy; Floxuridine; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver; Liver Neoplasms

1986
Influence of the administration of amifostine on the pharmacokinetics of 5-fluorouracil in patients with metastatic colorectal carcinoma.
    International journal of clinical pharmacology and therapeutics, 2000, Volume: 38, Issue:1

    Topics: Aged; Amifostine; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Interactions; Female; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Middle Aged

2000
Tolerability of the cytoprotective agent amifostine in elderly patients receiving chemotherapy: a comparative study.
    Anti-cancer drugs, 2001, Volume: 12, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amifostine; Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cyclophosphamide; Deoxycytidine; Doxorubicin; Epirubicin; Esophageal Neoplasms; Female; Fluorouracil; Gemcitabine; Humans; Hypertension; Hypocalcemia; Hypotension; Infusions, Intravenous; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Nausea; Paclitaxel; Pancreatic Neoplasms; Platinum; Prednisone; Premedication; Retrospective Studies; Vincristine

2001
Hypofractionated and accelerated radiotherapy with cytoprotection (HypoARC): a short, safe, and effective postoperative regimen for high-risk breast cancer patients.
    International journal of radiation oncology, biology, physics, 2002, Jan-01, Volume: 52, Issue:1

    Topics: Adult; Aged; Alkaline Phosphatase; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Cyclophosphamide; Dose Fractionation, Radiation; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Mastectomy; Mastectomy, Modified Radical; Middle Aged; Nausea; Radiation Pneumonitis; Radiation-Protective Agents; Radiobiology; Radiodermatitis; Radiotherapy, Adjuvant; Survival Analysis; Vomiting

2002
Rationale for a phase I/II radiation dose-escalation study with concurrent amifostine (Ethyol) and infusional 5-FU chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma.
    Seminars in radiation oncology, 2002, Volume: 12, Issue:1 Suppl 1

    Topics: Adenocarcinoma; Amifostine; Antimetabolites, Antineoplastic; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intravenous; Male; Neoplasm Recurrence, Local; Radiation Injuries; Radiation-Protective Agents; Radiotherapy Dosage; Radiotherapy, Conformal; Rectal Neoplasms

2002
Amifostine, in a reduced dose, protects against severe diarrhea associated with weekly fluorouracil and folinic acid chemotherapy in advanced colorectal cancer: a pilot study.
    Journal of pain and symptom management, 2003, Volume: 26, Issue:3

    Topics: Aged; Aged, 80 and over; Amifostine; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Pilot Projects; Severity of Illness Index

2003
Pilot study of postoperative reirradiation, chemotherapy, and amifostine after surgical salvage for recurrent head-and-neck cancer.
    International journal of radiation oncology, biology, physics, 2004, May-01, Volume: 59, Issue:1

    Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Child; Cisplatin; Combined Modality Therapy; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Prospective Studies; Radiation-Protective Agents; Radiotherapy Dosage; Survival Analysis

2004
[Minutes of the 23th meeting of the European Society for Therapeutic Radiology and Oncology (ESTRO). Amsterdam, 24-28 October 2004].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2005, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amifostine; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Mastectomy; Methotrexate; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation-Protective Agents; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Rectal Neoplasms; Time Factors

2005
Protective effects of amifostine and cyclooxygenase-1 inhibitor against normal human epidermal keratinocyte toxicity induced by methotrexate and 5-fluorouracil.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 105, Issue:1

    Topics: Allopurinol; Amifostine; Antimetabolites, Antineoplastic; Calcium; Cell Line; Cell Proliferation; Cell Survival; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Fibroblasts; Fluorouracil; Free Radical Scavengers; Glutamine; Humans; Keratinocytes; Methotrexate; Periodontal Ligament; Protective Agents; Pyrazoles; Reactive Oxygen Species; Stomatitis

2009
Amifostine reduces inflammation and protects against 5-fluorouracil-induced oral mucositis and hyposalivation.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2019, Feb-25, Volume: 52, Issue:3

    Topics: Amifostine; Animals; Cricetinae; Disease Models, Animal; Fluorouracil; Inflammation; Male; Protective Agents; Stomatitis; Xerostomia

2019