ambamustine has been researched along with melphalan in 4 studies
*Melphalan: An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen. [MeSH]
*Melphalan: An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen. [MeSH]
| Studies (ambamustine) | Trials (ambamustine) | Recent Studies (post-2010) (ambamustine) | Studies (melphalan) | Trials (melphalan) | Recent Studies (post-2010) (melphalan) |
|---|---|---|---|---|---|
| 28 | 1 | 0 | 8,134 | 1,351 | 1,972 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boschi, S; Cavo, M; Guidi, A; Tosi, P; Tura, S; Verlicchi, F; Visani, G | 1 |
| Bekesi, JG; Holland, JF; Houghton, JA; Houghton, PJ; Tharp, R | 1 |
| Bekesi, JG; Chin, SE; Holland, JF; Scanlon, KJ; Yagi, MJ | 2 |
4 other study(ies) available for ambamustine and melphalan
| Article | Year |
|---|---|
Evidence for increased intracellular transport of m-sarcolysine (alkylating moiety) when combined with two amino acid analogs (PTT-119).
Topics: Amino Acids; Biological Transport; Drug Combinations; Humans; Intracellular Membranes; Melphalan; Nitrogen Mustard Compounds; Osmolar Concentration | 1990 |
Evaluation of 3-(p-fluorophenyl)-L-alanyl-3-[m-bis-(2-chloroethyl) aminophenyl]-L-alanyl-L-methionine ethyl ester HCl (PTT.119) against xenografts of human rhabdomyosarcoma.
Topics: Animals; Antineoplastic Agents; Cell Line; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Immunosuppression Therapy; Leukocyte Count; Melphalan; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Nitrogen Mustard Compounds; Platelet Count; Rhabdomyosarcoma | 1988 |
Multiple transport pathways for L1210 cells: uptake of PTT.119, a bifunctional alkylator with carrier amino acids.
Topics: Alkylating Agents; Amino Acids; Animals; Biological Transport, Active; Leukemia L1210; Melphalan; Nitrogen Mustard Compounds; Sodium; Tumor Cells, Cultured | 1988 |
PTT.119, p-F-Phe-m-bis-(2-chloroethyl)amino-L-Phe-Met ethoxy HCl, a new chemotherapeutic agent active against drug-resistant tumor cell lines.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance; Leukemia L1210; Melphalan; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1985 |