amastatin has been researched along with 2-naphthylamide* in 1 studies
1 other study(ies) available for amastatin and 2-naphthylamide
| Article | Year |
|---|---|
Methionine enkephalin is hydrolyzed by aminopeptidase N on CD4+ and CD8+ spleen T cells.
Exogenous methionine enkephalin incubated with CD4+ or CD8+ T cells purified from murine spleen is metabolized primarily, if not exclusively, by aminopeptidase N (aminopeptidase M, EC 3.4.11.2), a membrane-anchored ectopeptidase. The enzyme activity is identified by its substrate specificity, sensitivity to inhibition by amastatin, and immunoreactivity with antibody to rat kidney aminopeptidase N. Activation of CD4+ T cells results in a small increase per cell in aminopeptidase N activity. Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Antibodies; CD13 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; CD8 Antigens; Cell Separation; Enkephalin, Methionine; Hydrolysis; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Peptides; Spleen; Substrate Specificity; T-Lymphocyte Subsets | 1994 |