amantadine and topiramate

amantadine has been researched along with topiramate in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Sanders, TA; Taylor, D; Werneke, U1
Hadjikoutis, S; Morgan, JE; Smith, PE; Wild, JM1
Crossman, AR; Hill, MP; Kobylecki, C; Ravenscroft, P1
Chung, KA; Goetz, CG; Hauser, RA; Merkitch, D; Nicholas, AP; Stacy, MA; Stebbins, GT1
Aktas, F; Erdoğan, E; Gündüz, ZB; Solmaz, M; Vatansev, H1

Reviews

3 review(s) available for amantadine and topiramate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Options for pharmacological management of obesity in patients treated with atypical antipsychotics.
    International clinical psychopharmacology, 2002, Volume: 17, Issue:4

    Topics: Amantadine; Antipsychotic Agents; Cimetidine; Cyclobutanes; Fluoxetine; Fructose; Humans; Lactones; Metformin; Nizatidine; Obesity; Orlistat; Topiramate; Weight Gain

2002
Ocular complications of neurological therapy.
    European journal of neurology, 2005, Volume: 12, Issue:7

    Topics: Acetazolamide; Adrenal Cortex Hormones; Amantadine; Anticonvulsants; Antitubercular Agents; Cholinergic Antagonists; Dopamine Agents; Ethambutol; Eye Diseases; Female; Fructose; Humans; Isoniazid; Male; Radiotherapy; Topiramate; Vigabatrin

2005

Trials

1 trial(s) available for amantadine and topiramate

ArticleYear
Topiramate as an adjunct to amantadine in the treatment of dyskinesia in parkinson's disease: A randomized, double-blind, placebo-controlled multicenter study.
    Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:9

    Topics: Amantadine; Anticonvulsants; Antiparkinson Agents; Dose-Response Relationship, Drug; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Follow-Up Studies; Humans; Male; Parkinson Disease; Seveso Accidental Release; Topiramate; Treatment Outcome

2017

Other Studies

6 other study(ies) available for amantadine and topiramate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Synergistic antidyskinetic effects of topiramate and amantadine in animal models of Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2011, Volume: 26, Issue:13

    Topics: Amantadine; Animals; Antiparkinson Agents; Behavior, Animal; Callithrix; Disease Models, Animal; Dopamine Agonists; Drug Synergism; Dyskinesia, Drug-Induced; Fructose; Levodopa; Male; MPTP Poisoning; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Sprague-Dawley; Topiramate

2011
Effects of amantadine and topiramate on neuronal damage in rats with experimental cerebral ischemia-reperfusion.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2021, Volume: 30, Issue:10

    Topics: Amantadine; Animals; Antioxidants; Biomarkers; Brain Ischemia; Male; Oxidative Stress; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Serum Albumin; Topiramate

2021