amantadine and riluzole

amantadine has been researched along with riluzole in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's8 (53.33)29.6817
2010's5 (33.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Vale, S1
Hersch, SM1
Gu, ZL; Qin, ZH; Wang, J1
Carta, M; Cenci, MA; Fisone, G; HÃ¥kansson, K; Lundblad, M; Usiello, A1
Bonelli, RM; Hofmann, P1
Howland, RH1
Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Oishi, R; Okuno, R1
Nag, N; Storey, E; Tarlac, V1
Armstrong, MJ; Miyasaki, JM1
Aksinenko, AY; Bachurin, SO; Dubrovskaya, ES; Epishina, TA; Fisenko, VP; Goreva, TV; Grigoriev, VV; Lapshina, MA; Makhaeva, GF; Maleev, GV; Shevtsova, EF; Steinberg, DA; Ustyugov, AA; Veselov, IM; Vinogradova, DV; Zamoyski, VL1

Reviews

5 review(s) available for amantadine and riluzole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Huntington's disease: prospects for neuroprotective therapy 10 years after the discovery of the causative genetic mutation.
    Current opinion in neurology, 2003, Volume: 16, Issue:4

    Topics: Amantadine; Anti-Dyskinesia Agents; Antiparkinson Agents; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Humans; Huntingtin Protein; Huntington Disease; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Point Mutation; Riluzole; Tetrabenazine; Time Factors

2003
Development of novel therapies for Huntington's disease: hope and challenge.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:2

    Topics: Amantadine; Animals; Cell Transplantation; Drugs, Chinese Herbal; Humans; Huntingtin Protein; Huntington Disease; Mutation; Neostriatum; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Riluzole

2005
A systematic review of the treatment studies in Huntington's disease since 1990.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:2

    Topics: Amantadine; Antipsychotic Agents; Chorea; Depression; Humans; Huntington Disease; Neuroprotective Agents; Riluzole; Sexual Dysfunctions, Psychological; Tetrabenazine

2007
Glutamate-modulating drugs & the treatment of mental disorders.
    Journal of psychosocial nursing and mental health services, 2007, Volume: 45, Issue:1

    Topics: Acamprosate; Amantadine; Cycloserine; Glutamic Acid; Humans; Ketamine; Lamotrigine; Memantine; Mental Disorders; Psychotropic Drugs; Riluzole; Taurine; Triazines

2007

Other Studies

10 other study(ies) available for amantadine and riluzole

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
Drug treatments of levodopa-induced dyskinesias.
    Lancet (London, England), 1999, Aug-07, Volume: 354, Issue:9177

    Topics: Amantadine; Antiparkinson Agents; Dopamine Agents; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Humans; Levodopa; Patient Selection; Receptors, N-Methyl-D-Aspartate; Riluzole; Treatment Outcome

1999
Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia.
    Experimental neurology, 2005, Volume: 194, Issue:1

    Topics: Adenosine A2 Receptor Agonists; Adrenergic Agents; Amantadine; Animals; Antiparkinson Agents; Basal Ganglia; Buspirone; Disease Models, Animal; Disease Progression; Dopamine Agonists; Drug Administration Schedule; Dyskinesia, Drug-Induced; Indoles; Levodopa; Male; Mice; Mice, Inbred C57BL; Oxidopamine; Parkinsonian Disorders; Purines; Receptor, Adenosine A2A; Receptors, Dopamine D2; Reproducibility of Results; Riluzole; Treatment Outcome

2005
Effects of glutamate-related drugs on marble-burying behavior in mice: implications for obsessive-compulsive disorder.
    European journal of pharmacology, 2008, May-31, Volume: 586, Issue:1-3

    Topics: Acoustic Stimulation; Amantadine; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memantine; Mice; Mice, Inbred ICR; Motor Activity; Obsessive-Compulsive Disorder; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Riluzole

2008
Assessing the efficacy of specific cerebellomodulatory drugs for use as therapy for spinocerebellar ataxia type 1.
    Cerebellum (London, England), 2013, Volume: 12, Issue:1

    Topics: Amantadine; Animals; Ataxin-1; Ataxins; Buspirone; Disease Models, Animal; Dopamine Agents; Genotype; Hypnotics and Sedatives; Kyphosis; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Phenotype; Purkinje Cells; Pyridines; Riluzole; Serotonin Receptor Agonists; Spinocerebellar Ataxias; Zolpidem

2013
Evidence-based guideline: pharmacologic treatment of chorea in Huntington disease: report of the guideline development subcommittee of the American Academy of Neurology.
    Neurology, 2012, Aug-07, Volume: 79, Issue:6

    Topics: Adult; Amantadine; Anticonvulsants; Chorea; Evidence-Based Medicine; Humans; Huntington Disease; Riluzole

2012
New Adamantane-Containing Edaravone Conjugates as Potential Neuroprotective Agents for ALS Treatments.
    Molecules (Basel, Switzerland), 2023, Nov-13, Volume: 28, Issue:22

    Topics: Adamantane; Amantadine; Amyotrophic Lateral Sclerosis; Edaravone; Humans; Neuroprotective Agents; Riluzole

2023