amantadine and propranolol

amantadine has been researched along with propranolol in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199016 (37.21)18.7374
1990's2 (4.65)18.2507
2000's13 (30.23)29.6817
2010's11 (25.58)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Agnoli, A; Carolei, A; Casacchia, M; Fazio, C; Zamponi, A1
Stone, TW1
Eisdorfer, C1
McKinney, AS1
Bergen, D; Goetz, C; Klawans, HL1
Salvador, AM1
Camanni, F; Isaia, GC; Massara, F; Molinatti, GM1
Culvenor, AJ; Dawson, RM; Freeman, SE; Keeghan, AM1
Casey, DE; Keepers, GA1
Young, RR1
Jan, JE; Wilson, RA1
Schwab, RS; Young, RR1
Kubo, T; Takagi, H1
Bauman, AW; Hammond, EJ; Karas, BJ; Wilder, BJ1
Goetz, CG; Klawans, HL; Tanner, CM1
Hostetler, KY; Matsuzawa, Y1
Ahlskog, JE1
Guin-Renfroe, S; Meythaler, JM; Wilkinson, R1
Koller, W; Marjama-Lyons, J1
Fleminger, S; Greenwood, RJ; Oliver, DL2
Schmidt, JG; Schneider, WN1
Atzram, M; Dackis, C; Gariti, P; Kampman, KM; Lynch, KG; O'Brien, CP; Pettinati, H; Sparkman, T; Tirado, C1
Aschermann, Z; Horváth, K; Komoly, S; Kovács, A; Kovács, N1
Lerner, PP; Lerner, V; Miodownik, C1

Reviews

8 review(s) available for amantadine and propranolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical management of acute neuroleptic-induced extrapyramidal syndromes.
    Current psychiatric therapies, 1986, Volume: 23

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Akathisia, Drug-Induced; Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Child; Disease Susceptibility; Double-Blind Method; Dystonia; Female; Humans; Male; Middle Aged; Parasympatholytics; Parkinson Disease, Secondary; Propranolol; Psychomotor Agitation; Risk

1986
Medical treatment of later-stage motor problems of Parkinson disease.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:12

    Topics: Amantadine; Antiparkinson Agents; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Cholinergic Antagonists; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Combinations; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Humans; Levodopa; Nitriles; Nitrophenols; Parkinson Disease, Secondary; Propranolol; Randomized Controlled Trials as Topic; Selegiline; Tolcapone

1999
Tremor-predominant Parkinson's disease. Approaches to treatment.
    Drugs & aging, 2000, Volume: 16, Issue:4

    Topics: Acetates; Amantadine; Amines; Antiparkinson Agents; Botulinum Toxins; Cholinergic Antagonists; Clonazepam; Clozapine; Cyclohexanecarboxylic Acids; Dopamine Agonists; Electric Stimulation Therapy; Gabapentin; Gamma Rays; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Neurosurgical Procedures; Parkinson Disease; Propranolol; Radiosurgery; Thalamus; Tremor

2000
Pharmacological management for agitation and aggression in people with acquired brain injury.
    The Cochrane database of systematic reviews, 2003, Issue:1

    Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidate; Neuroprotective Agents; Pindolol; Propranolol; Randomized Controlled Trials as Topic

2003
Pharmacological management for agitation and aggression in people with acquired brain injury.
    The Cochrane database of systematic reviews, 2006, Oct-18, Issue:4

    Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidate; Neuroprotective Agents; Pindolol; Propranolol; Psychomotor Agitation; Randomized Controlled Trials as Topic

2006
[Treatment of tardive syndromes].
    Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirata, 2014, Volume: 29, Issue:2

    Topics: Amantadine; Antipsychotic Agents; Botulinum Toxins; Central Nervous System Agents; Cholinergic Antagonists; Clinical Trials as Topic; Clonazepam; Deep Brain Stimulation; Dopamine Antagonists; Ginkgo biloba; Humans; Levetiracetam; Movement Disorders; Nootropic Agents; Piracetam; Primary Prevention; Propranolol; Syndrome; Tetrabenazine; Vitamin E

2014
Tardive dyskinesia (syndrome): Current concept and modern approaches to its management.
    Psychiatry and clinical neurosciences, 2015, Volume: 69, Issue:6

    Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; alpha-Tocopherol; Amantadine; Anticonvulsants; Antioxidants; Antipsychotic Agents; Clonazepam; Dopamine Agents; Drugs, Chinese Herbal; Fatty Acids, Omega-3; Ginkgo biloba; Humans; Isoleucine; Isoxazoles; Leucine; Levetiracetam; Melatonin; Movement Disorders; Nootropic Agents; Piracetam; Plant Extracts; Propranolol; Pyridoxine; Resveratrol; Stilbenes; Tetrabenazine; Valine; Vitamins; Zonisamide

2015

Trials

2 trial(s) available for amantadine and propranolol

ArticleYear
Treatment of valproate tremors.
    Neurology, 1983, Volume: 33, Issue:10

    Topics: Amantadine; Cyproheptadine; Diphenhydramine; Humans; Propranolol; Tremor; Valproic Acid

1983
A double-blind, placebo-controlled trial of amantadine, propranolol, and their combination for the treatment of cocaine dependence in patients with severe cocaine withdrawal symptoms.
    Drug and alcohol dependence, 2006, Nov-08, Volume: 85, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Amantadine; Analgesics, Non-Narcotic; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Neurologic Examination; Patient Dropouts; Propranolol; Substance Abuse Detection; Substance Withdrawal Syndrome

2006

Other Studies

33 other study(ies) available for amantadine and propranolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
[Therapy of Parkinson's disease. Practical criteria of treatment].
    Recenti progressi in medicina, 1976, Volume: 60, Issue:5

    Topics: Amantadine; Antiparkinson Agents; Benserazide; Carbidopa; Cyproheptadine; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Levodopa; Parasympatholytics; Parkinson Disease; Piribedil; Pizotyline; Propranolol

1976
Comparison of neuronal responses to amantadine and rimantadine: use of alpha-flupenthixol.
    Experimental neurology, 1978, Volume: 62, Issue:2

    Topics: Adamantane; Amantadine; Animals; Bridged-Ring Compounds; Cerebral Cortex; Dopamine Antagonists; Flupenthixol; Male; Neurons; Phentolamine; Propranolol; Rats; Synaptic Transmission; Thioxanthenes

1978
Observations on the psychopharmacology of the aged.
    Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:2

    Topics: Aged; Amantadine; Antidepressive Agents; Antipsychotic Agents; Basal Ganglia Diseases; Butyrophenones; Cognition; Cognition Disorders; Creutzfeldt-Jakob Syndrome; Dementia; Humans; Lithium; Movement Disorders; Phenothiazines; Phytotherapy; Plants, Medicinal; Propranolol; Psychotic Disorders; Psychotropic Drugs; Rauwolfia; Thiothixene

1975
The shaking patient. Diagnosis and management of tremor.
    Postgraduate medicine, 1977, Volume: 61, Issue:2

    Topics: Amantadine; Carbidopa; Cerebellar Diseases; Humans; Levodopa; Parkinson Disease; Propranolol; Tremor

1977
Levodopa-induced myoclonus.
    Archives of neurology, 1975, Volume: 32, Issue:5

    Topics: 5-Hydroxytryptophan; Aged; Amantadine; Amphetamine; Animals; Benztropine; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Levodopa; Male; Methysergide; Middle Aged; Movement Disorders; Myoclonus; Parkinson Disease; Propranolol; Serotonin; Serotonin Antagonists; Sleep; Trihexyphenidyl

1975
The action of amantadine on the rat uterus: its interaction with oxytocin and the effects of several ionic modifications of the medium.
    European journal of pharmacology, 1975, Volume: 31, Issue:1

    Topics: Amantadine; Animals; Calcium; Drug Interactions; Female; In Vitro Techniques; Magnesium; Oxytocin; Potassium; Propranolol; Rats; Theophylline; Uterus

1975
Dopaminergic control of growth hormone secretion in normal and acromegalic subjects.
    Panminerva medica, 1975, Volume: 17, Issue:4

    Topics: Acromegaly; Amantadine; Bromocriptine; Ergolines; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Levodopa; Phentolamine; Pituitary Gland; Propranolol

1975
Interactions of amantadine with the cardiac muscarinic receptor.
    Journal of molecular and cellular cardiology, 1985, Volume: 17, Issue:1

    Topics: Acetylcholine; Amantadine; Animals; Binding, Competitive; Dihydroalprenolol; Electrocardiography; Guinea Pigs; Heart Atria; Heart Conduction System; Ion Channels; Myocardial Contraction; Nifedipine; Nitrendipine; Propranolol; Quinuclidinyl Benzilate; Receptors, Muscarinic

1985
Treatment of parkinsonism.
    The New England journal of medicine, 1972, Nov-16, Volume: 287, Issue:20

    Topics: Amantadine; Dihydroxyphenylalanine; Humans; Parkinson Disease; Phenothiazines; Propranolol

1972
Unusual late neurological sequelae in galactosaemia.
    Developmental medicine and child neurology, 1973, Volume: 15, Issue:1

    Topics: Adult; Age Factors; Amantadine; Bender-Gestalt Test; Cerebellar Diseases; Diet Therapy; Erythrocytes; Functional Laterality; Galactosemias; Humans; Intellectual Disability; Lactose; Male; Movement Disorders; Muscle Tonus; Nucleotidyltransferases; Propranolol; Speech Disorders

1973
Non-resting tremor in Parkinson's disease.
    Transactions of the American Neurological Association, 1971, Volume: 96

    Topics: Aged; Amantadine; Dihydroxyphenylalanine; Humans; Male; Parkinson Disease; Propranolol; Tremor

1971
A possible mechanism of arrhythmia induced by 1-adamantanamine.
    Japanese journal of pharmacology, 1967, Volume: 17, Issue:4

    Topics: Amantadine; Animals; Arrhythmias, Cardiac; Catecholamines; Cocaine; Electrocardiography; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Norepinephrine; Propranolol; Rabbits; Reserpine; Ventricular Fibrillation

1967
The pharmacology of olivopontocerebellar atrophy.
    Advances in neurology, 1984, Volume: 41

    Topics: Adult; Amantadine; Atrophy; Baclofen; Brain Diseases; Carbidopa; Cerebellar Ataxia; Female; Humans; Levodopa; Male; Middle Aged; Olivary Nucleus; Pons; Propranolol; Syndrome

1984
Studies on the mechanism of drug-induced lipidosis. Cationic amphiphilic drug inhibition of lysosomal phospholipases A and C.
    Biochemical pharmacology, 1981, May-15, Volume: 30, Issue:10

    Topics: Amantadine; Aniline Compounds; Animals; Chlorphentermine; Chlorpromazine; Heptanes; Imipramine; Lipidoses; Liver; Lysosomes; Male; Pharmacology; Phospholipases; Phospholipases A; Propranolol; Rats; Tripelennamine; Type C Phospholipases

1981
Neuroleptic malignant syndrome induced by haloperidol following traumatic brain injury.
    Brain injury, 1999, Volume: 13, Issue:12

    Topics: Adolescent; Amantadine; Brain Injuries; Dopamine Agents; Dopamine Antagonists; Fever; Haloperidol; Humans; Male; Neuroleptic Malignant Syndrome; Propranolol; Treatment Outcome; Vasodilator Agents

1999
Pharmacologic treatment of cognitive deficits and hypersexuality due to "shaken-baby syndrome".
    Neurorehabilitation and neural repair, 2000, Volume: 14, Issue:2

    Topics: Adrenergic beta-Antagonists; Amantadine; Child; Child Behavior Disorders; Cognition Disorders; Dopamine Agents; Female; Humans; Propranolol; Sexual Behavior; Shaken Baby Syndrome; Treatment Outcome

2000