amantadine and procyclidine

amantadine has been researched along with procyclidine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hecht, P; Kornhuber, J; Koutsilieri, E; Kroemer, RT; Liedl, KR; Riederer, P1
Topliss, JG; Yoshida, F1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Mindham, RH1
Taylor, J1
Butzer, JF; Sahs, AL; Silver, DE1
Parkenberg, H1
Benesová, O1

Reviews

2 review(s) available for amantadine and procyclidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Review of current pharmacotherapy of Parkinsonism. Comprehensive review].
    Ceskoslovenska neurologie, 1973, Volume: 36, Issue:3

    Topics: 5-Hydroxytryptophan; Amantadine; Anticonvulsants; Apomorphine; Benztropine; Carboxy-Lyases; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Humans; Parasympatholytics; Parkinson Disease; Procyclidine; Trihexyphenidyl

1973

Trials

2 trial(s) available for amantadine and procyclidine

ArticleYear
Assessment of drugs in schizophrenia. Asessment of drug-induced extrapyramidal reactions and of drugs given for their control.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:3 Suppl 2

    Topics: Amantadine; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Clinical Trials as Topic; Drug Evaluation; Fluphenazine; Humans; Orphenadrine; Parkinson Disease, Secondary; Piribedil; Procyclidine

1976
Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up.
    Neurology, 1975, Volume: 25, Issue:7

    Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine; Drug Evaluation; Female; Follow-Up Studies; Humans; Locomotion; Long-Term Care; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Procyclidine; Time Factors; Tremor; Trihexyphenidyl

1975

Other Studies

9 other study(ies) available for amantadine and procyclidine

ArticleYear
Quantitative analysis of the structural requirements for blockade of the N-methyl-D-aspartate receptor at the phencyclidine binding site.
    Journal of medicinal chemistry, 1998, Jan-29, Volume: 41, Issue:3

    Topics: Binding Sites; Excitatory Amino Acid Antagonists; Humans; Molecular Structure; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Parkinson's disease.
    The Australian nurses' journal. Royal Australian Nursing Federation, 1977, Volume: 7, Issue:5

    Topics: Amantadine; Benztropine; Humans; Levodopa; Parkinson Disease; Procyclidine; Trihexyphenidyl

1977
[Treatment of parkinsonism].
    Ugeskrift for laeger, 1976, Apr-26, Volume: 138, Issue:18

    Topics: Amantadine; Benztropine; Biperiden; Humans; Levodopa; Orphenadrine; Parkinson Disease; Procyclidine; Trihexyphenidyl

1976