Compounds > amantadine

amantadine and n-methylaspartate

amantadine has been researched along with n-methylaspartate in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (65.00)18.2507
2000's3 (15.00)29.6817
2010's3 (15.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Feuerstein, TJ; Jackisch, R; Koch, R; Lücking, CH; Lupp, A1
Booij, J; Drukarch, B; Stoof, JC; Wolters, EC1
Vamvakidès, A1
Danysz, W; Dill, D; Gossel, M; Quack, G; Zajaczkowski, W1
Danysz, W; Quack, G; Rogoz, Z; Skuza, G1
Danysz, W; Mobley, SL; Wenk, GL1
Kornhuber, J; Weller, M1
Ferger, D; Krieglstein, J1
Krishtal, OA; Panchenko, VA; Parsons, CG; Pinchenko, VO; Tsyndrenko, AY1
Eckert, J; Fritze, J; Northoff, G1
Aizenman, E; Blanpied, TA; Boeckman, FA; Johnson, JW1
Capelli, AM; Cugola, A; Curcuruto, O; Di Fabio, R; Feriani, A; Gastaldi, P; Gaviraghi, G; Marchioro, C; Micheli, F; Orlandi, A; Pozzan, A; Quaglia, AM; Reggiani, A; van Amsterdam, F1
Bogerts, B; Böker, H; Danos, P; Lins, H; Northoff, G1
Chase, TN; Farmer, C; Gillespie, M; Morris, MJ; Mosby, K; Verhagen Metman, L; Wuu, J1
Storozhuk, VM; Zinyuk, LE1
De Clercq, E; Hay, AJ; Kolocouris, A; López-Querol, M; Martin, SR; Neyts, J; Padalko, E; Spearpoint, P; Sureda, FX1
Büttner, T; Csoti, I; Kassubek, J; Reichmann, H; Riederer, P; Schulz, JB; Wüllner, U1
Nanoff, C; Pifl, C; Rebernik, P; Reither, H; Sommerauer, C1
Dhossche, D; Goetz, M; Hrdlicka, M; Kitzlerova, E1
Akdağlı Ekici, A; Alagöz, A; Ayaz, E; Doğan, G; Karaca, O; Kayır, S; Özcan, O; Yağan, Ö; Yalvaç, M; Zengin, EN; Zengin, M1

Reviews

3 review(s) available for amantadine and n-methylaspartate

ArticleYear
[Action mechanism of adamantamines: do their activity on glutamatergic receptors intervene in the expression of their pharmacological profile?].
    Annales pharmaceutiques francaises, 1991, Volume: 49, Issue:5

    Topics: Amantadine; Antibodies; Antiparkinson Agents; gamma-Aminobutyric Acid; Glycine; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate

1991
[New therapeutic possibilities with low-affinity NMDA receptor antagonists].
    Der Nervenarzt, 1996, Volume: 67, Issue:1

    Topics: Aged; Alzheimer Disease; Amantadine; Antiparkinson Agents; Excitatory Amino Acid Antagonists; Glutamine; Humans; Memantine; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine

1996
[On the role of MAO B inhibitors and NMDA antagonists in the therapy of Parkinson's disease].
    Fortschritte der Neurologie-Psychiatrie, 2010, Volume: 78 Suppl 1

    Topics: Amantadine; Excitatory Amino Acid Antagonists; Humans; Indans; Memantine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; N-Methylaspartate; Parkinson Disease; Piperidines; Selegiline

2010

Trials

2 trial(s) available for amantadine and n-methylaspartate

ArticleYear
Huntington's disease: a randomized, controlled trial using the NMDA-antagonist amantadine.
    Neurology, 2002, Sep-10, Volume: 59, Issue:5

    Topics: Adult; Aged; Amantadine; Chorea; Cognition; Cross-Over Studies; Dopamine Agents; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Huntington Disease; Male; Middle Aged; N-Methylaspartate; Treatment Outcome

2002
Neuroprotective effects of amantadine for experimental acute carbon monoxide poisoning.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:19

    Topics: Amantadine; Animals; Antioxidants; Arginine; Carbon Monoxide; Carbon Monoxide Poisoning; Catalase; D-Aspartic Acid; Formaldehyde; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Paraffin; Rats; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase

2022

Other Studies

15 other study(ies) available for amantadine and n-methylaspartate

ArticleYear
Inhibitory effects of the antiparkinsonian drugs memantine and amantadine on N-methyl-D-aspartate-evoked acetylcholine release in the rabbit caudate nucleus in vitro.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: Acetylcholine; Amantadine; Animals; Caudate Nucleus; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; Memantine; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium

1992
The anti-parkinsonian drug amantadine inhibits the N-methyl-D-aspartic acid-evoked release of acetylcholine from rat neostriatum in a non-competitive way.
    European journal of pharmacology, 1992, Mar-31, Volume: 213, Issue:3

    Topics: Acetylcholine; Amantadine; Animals; Antiparkinson Agents; Binding, Competitive; Corpus Striatum; Dopamine; Male; N-Methylaspartate; Rats; Rats, Inbred Strains

1992
Are NMDA antagonistic properties relevant for antiparkinsonian-like activity in rats?--case of amantadine and memantine.
    Journal of neural transmission. Parkinson's disease and dementia section, 1994, Volume: 7, Issue:3

    Topics: Amantadine; Animals; Catalepsy; Dizocilpine Maleate; Locomotion; Male; Memantine; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra

1994
Memantine, amantadine, and L-deprenyl potentiate the action of L-dopa in monoamine-depleted rats.
    Journal of neural transmission. General section, 1994, Volume: 98, Issue:1

    Topics: Amantadine; Animals; Bromocriptine; Dopamine; Drug Synergism; Levodopa; Male; Memantine; Motor Activity; N-Methylaspartate; Parkinson Disease; Rats; Rats, Wistar; Selegiline

1994
MK-801, memantine and amantadine show neuroprotective activity in the nucleus basalis magnocellularis.
    European journal of pharmacology, 1995, Oct-06, Volume: 293, Issue:3

    Topics: Amantadine; Animals; Basal Ganglia; Cerebral Cortex; Choline O-Acetyltransferase; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Memantine; N-Methylaspartate; Nervous System Diseases; Neuroprotective Agents; Rats; Receptors, N-Methyl-D-Aspartate

1995
Determination of intracellular Ca2+ concentration can be a useful tool to predict neuronal damage and neuroprotective properties of drugs.
    Brain research, 1996, Sep-02, Volume: 732, Issue:1-2

    Topics: Amantadine; Analysis of Variance; Animals; Biomarkers; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Chickens; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Kinetics; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Quinoxalines; Sodium Cyanide; Telencephalon; Time Factors

1996
Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine.
    The European journal of neuroscience, 1996, Volume: 8, Issue:3

    Topics: Amantadine; Animals; Dose-Response Relationship, Drug; Hippocampus; Ketamine; Memantine; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1996
Glutamatergic dysfunction in catatonia? Successful treatment of three acute akinetic catatonic patients with the NMDA antagonist amantadine.
    Journal of neurology, neurosurgery, and psychiatry, 1997, Volume: 62, Issue:4

    Topics: Adult; Amantadine; Catatonia; Glutamic Acid; Humans; Infusions, Intravenous; Male; N-Methylaspartate

1997
Trapping channel block of NMDA-activated responses by amantadine and memantine.
    Journal of neurophysiology, 1997, Volume: 77, Issue:1

    Topics: Amantadine; Animals; Antiparkinson Agents; Cells, Cultured; CHO Cells; Cricetinae; DNA; Excitatory Amino Acid Agonists; Ion Channels; Kinetics; Memantine; Membrane Potentials; Models, Neurological; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

1997
Cycloalkyl indole-2-carboxylates as useful tools for mapping the "north-eastern" region of the glycine binding site associated with the NMDA receptor.
    Archiv der Pharmazie, 1999, Volume: 332, Issue:3

    Topics: Amantadine; Animals; Anticonvulsants; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Ligands; Mice; Models, Molecular; N-Methylaspartate; Norbornanes; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Seizures

1999
Therapeutic efficacy of N-methyl D-aspartate antagonist amantadine in febrile catatonia.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:5

    Topics: Adult; Amantadine; Bipolar Disorder; Catatonia; Dopamine Agents; Excitatory Amino Acid Agonists; Fever; Humans; Male; N-Methylaspartate; Psychotic Disorders

1999
Specific features of sensorimotor cerebral cortex activity modulation by dopamine releaser amantadine.
    Experimental brain research, 2007, Volume: 182, Issue:2

    Topics: Action Potentials; Amantadine; Animals; Behavior, Animal; Cats; Conditioning, Classical; Dopamine; Dopamine Agents; Electric Stimulation; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Movement; N-Methylaspartate; Neurons; Reaction Time; Somatosensory Cortex; Sulpiride; Wakefulness

2007
Comparisons of the influenza virus A M2 channel binding affinities, anti-influenza virus potencies and NMDA antagonistic activities of 2-alkyl-2-aminoadamantanes and analogues.
    Bioorganic & medicinal chemistry letters, 2008, Dec-01, Volume: 18, Issue:23

    Topics: Adamantane; Amantadine; Antiviral Agents; Influenza A virus; Molecular Structure; N-Methylaspartate; Structure-Activity Relationship; Viral Matrix Proteins

2008
The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine.
    Neuropharmacology, 2012, Volume: 62, Issue:4

    Topics: Amantadine; Antiparkinson Agents; Cell Line; Dopamine Plasma Membrane Transport Proteins; HEK293 Cells; Humans; N-Methylaspartate; Norepinephrine Plasma Membrane Transport Proteins; Receptors, Adrenergic, alpha-2

2012
Combined use of electroconvulsive therapy and amantadine in adolescent catatonia precipitated by cyber-bullying.
    Journal of child and adolescent psychopharmacology, 2013, Volume: 23, Issue:3

    Topics: Adolescent; Amantadine; Bullying; Catatonia; Combined Modality Therapy; Dopamine Agents; Electroconvulsive Therapy; Female; Humans; Internet; N-Methylaspartate

2013