amantadine has been researched along with morphine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (42.86) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gressier, H; Malecot, E; Poignant, JC | 1 |
| Lahti, RA; McAllister, B; Wozniak, J | 1 |
| Spoerlein, MT; VanderWende, C | 1 |
| Frohberg, H | 1 |
| Spoerlein, MT; Vallano, ML; VanderWende, C | 1 |
| Katz, J; Koren, G; Snijdelaar, DG | 1 |
| Meert, TF; Snijdelaar, DG; van Rijn, CM; Vinken, P | 1 |
| Babapour, V; Cheraghiyan, S; Maleki, SA; Mehr, SE; Nouri, MH; Samini, M | 1 |
| Bujak-Gizycka, B; Korbut, R; Madej, J; Olszanecki, R; Suski, M | 1 |
| Bujak-Giżycka, B; Dobrogowski, J; Kącka, K; Korbut, R; Madej, J; Olszanecki, R; Suski, M | 1 |
| Klambeck, M; Kopf, A; Mousa, SA; Schäfer, M; Treskatsch, S | 1 |
| Kolik, LG; Konstantinopolsky, MA | 1 |
2 review(s) available for amantadine and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Present position of the toxicology of drugs].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amantadine; Aminopterin; Animals; Animals, Newborn; Aspirin; Carcinogens; Codeine; Dogs; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Female; Fertility; Haplorhini; Humans; Indomethacin; Male; Meclizine; Methods; Mice; Morphine; Mutation; Nalidixic Acid; Neoplasms; Neoplasms, Experimental; Pharmacogenetics; Pregnancy; Pregnancy Complications; Rabbits; Rats; Reproduction; Sex Factors; Statistics as Topic; Time Factors | 1970 |
3 trial(s) available for amantadine and morphine
| Article | Year |
|---|---|
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study.
Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Biotransformation; Double-Blind Method; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain Threshold; Pain, Postoperative; Patient Satisfaction; Pilot Projects; Postoperative Nausea and Vomiting; Prostatectomy; Pruritus; Surveys and Questionnaires; Treatment Outcome | 2004 |
Beneficial effect of amantadine on postoperative pain reduction and consumption of morphine in patients subjected to elective spine surgery.
Topics: Adolescent; Amantadine; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Double-Blind Method; Female; Fentanyl; Humans; Male; Morphine; Narcotics; Orthopedic Procedures; Pain, Postoperative; Spine | 2012 |
Influence of high-dose intraoperative remifentanil with or without amantadine on postoperative pain intensity and morphine consumption in major abdominal surgery patients: a randomised trial.
Topics: Abdomen; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Pain, Postoperative; Piperidines; Remifentanil | 2014 |
16 other study(ies) available for amantadine and morphine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Comparative effects of apomorphine, piribedil and other neurotropic agents on central analgesic-induced catatonia in the rat.
Topics: Amantadine; Analgesics, Opioid; Animals; Antiparkinson Agents; Apomorphine; Atropine; Benserazide; Benzyl Compounds; Catatonia; Dextroamphetamine; Dextromoramide; Dihydroxyphenylalanine; Dioxoles; Dose-Response Relationship, Drug; Humans; Male; Morphine; Piperazines; Pyrimidines; Rats; Time Factors; Trihexyphenidyl | 1974 |
Apomorphine antagonism of the elevation of homovanillic acid induced by antipsychotic drugs.
Topics: Amantadine; Animals; Apomorphine; Brain; Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Haloperidol; Homovanillic Acid; Mice; Morphine; Phenylacetates; Receptors, Adrenergic; Structure-Activity Relationship; Synaptic Transmission; Thiothixene; Tranquilizing Agents; Trifluoperazine | 1972 |
Role of dopaminergic receptors in morphine analgesia and tolerance.
Topics: Amantadine; Analgesia; Animals; Apomorphine; Dibenzothiazepines; Dopamine; Drug Synergism; Drug Tolerance; Male; Mice; Mice, Inbred Strains; Morphine; Perphenazine; Phenoxybenzamine; Receptors, Adrenergic; Serine; Spiro Compounds | 1973 |
Morphine enhances high-affinity choline uptake in mouse striatum.
Topics: Amantadine; Animals; Behavior, Animal; Choline; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Haloperidol; Male; Mice; Morphine; Sodium | 1982 |
Effects of pre-treatment with amantadine on morphine induced antinociception during second phase formalin responses in rats.
Topics: Amantadine; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Motor Activity; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rotarod Performance Test; Treatment Outcome | 2005 |
Potentiation of morphine-induced conditioned place preference with concurrent use of amantadine and fluvoxamine by the intraperitoneal and intracerebroventricular injection in rat.
Topics: Amantadine; Animals; Association Learning; Behavior, Animal; Conditioning, Classical; Dopamine Agents; Drug Synergism; Fluvoxamine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Morphine; Narcotics; Rats; Rats, Wistar; Reward; Selective Serotonin Reuptake Inhibitors | 2008 |
[Evaluation of morphine metabolism in presence of amantadine and dextromethorphan in human serum by high performance liquid chromatography coupled with mass spectrometry (LC/MS) method].
Topics: Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Chromatography, High Pressure Liquid; Dextromethorphan; Dose-Response Relationship, Drug; Drug Interactions; Humans; Mass Spectrometry; Morphine; Pain; Pain Threshold | 2008 |
Comparative Assessment of the Effectiveness of Noncompetitive NMDA Receptor Antagonists Amantadine and Hemantane in Morphine Withdrawal Syndrome Model.
Topics: Adamantane; Amantadine; Animals; Gene Expression; Hyperalgesia; Injections, Intraperitoneal; Male; Morphine; Morphine Dependence; Motor Activity; Narcotic Antagonists; Rats; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Weight Loss | 2019 |